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Illumina Body Map 2 (GSE30611)

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Results for MAF_NRL

Z-value: 1.66

Motif logo

Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
ENSG00000178573.7 MAF bZIP transcription factor
ENSG00000129535.13 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NRLhg38_v1_chr14_-_24084625_24084641-0.261.6e-01Click!
MAFhg38_v1_chr16_-_79600698_796007230.096.3e-01Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_116829898 11.38 ENST00000227667.8
ENST00000375345.3
apolipoprotein C3
chr4_+_77605807 10.63 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr1_-_56966133 10.61 ENST00000535057.5
ENST00000543257.5
complement C8 beta chain
chr1_-_56966006 9.97 ENST00000371237.9
complement C8 beta chain
chr11_+_116830529 8.45 ENST00000630701.1
apolipoprotein C3
chr22_+_20774092 7.50 ENST00000215727.10
serpin family D member 1
chr1_+_207104226 6.07 ENST00000367070.8
complement component 4 binding protein alpha
chr1_+_207104287 5.99 ENST00000421786.5
complement component 4 binding protein alpha
chr5_-_156963222 5.80 ENST00000407087.4
ENST00000274532.7
T cell immunoglobulin and mucin domain containing 4
chr19_+_44914247 5.51 ENST00000588750.5
ENST00000588802.5
apolipoprotein C1
chr9_-_114078293 5.45 ENST00000265132.8
alpha-1-microglobulin/bikunin precursor
chr14_-_105771405 5.02 ENST00000641136.1
ENST00000390551.6
immunoglobulin heavy constant gamma 3 (G3m marker)
chr19_+_44914833 4.82 ENST00000589078.1
ENST00000586638.5
apolipoprotein C1
chr9_+_136945234 4.53 ENST00000371634.7
complement C8 gamma chain
chr5_+_132873660 4.35 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr19_+_44914588 4.20 ENST00000592535.6
apolipoprotein C1
chr16_+_176659 4.16 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr10_+_94683722 4.14 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr22_+_22811737 4.04 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr2_-_187554351 3.70 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr6_-_7910776 3.66 ENST00000379757.9
thioredoxin domain containing 5
chr14_-_106538331 3.64 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr11_-_116837586 3.63 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
apolipoprotein A1
chr17_+_42900791 3.55 ENST00000592383.5
ENST00000253801.7
ENST00000585489.1
glucose-6-phosphatase catalytic subunit 1
chr22_+_22880706 3.52 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr10_+_94683771 3.45 ENST00000339022.6
cytochrome P450 family 2 subfamily C member 18
chr14_-_106235582 3.26 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr20_+_46709623 3.22 ENST00000359271.4
solute carrier family 2 member 10
chrX_-_106038721 3.22 ENST00000372563.2
serpin family A member 7
chr3_+_52794768 3.21 ENST00000621946.4
ENST00000416872.6
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr11_+_78063851 2.93 ENST00000281030.2
thyroid hormone responsive
chr12_-_52903648 2.85 ENST00000546900.1
keratin 8
chr6_+_31927683 2.82 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr1_-_153608136 2.76 ENST00000368703.6
S100 calcium binding protein A16
chr2_-_187554473 2.73 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr3_-_50303565 2.72 ENST00000266031.8
ENST00000395143.6
ENST00000457214.6
ENST00000447605.2
ENST00000395144.7
ENST00000418723.1
hyaluronidase 1
chr2_+_88885397 2.67 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr6_+_31927703 2.63 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr6_+_31927486 2.62 ENST00000442278.6
complement C2
chr17_+_6641008 2.51 ENST00000570330.5
thioredoxin domain containing 17
chr9_-_33447553 2.49 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr20_-_49482645 2.49 ENST00000371741.6
potassium voltage-gated channel subfamily B member 1
chr22_+_22380766 2.49 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr3_+_186613052 2.43 ENST00000411641.7
ENST00000273784.5
alpha 2-HS glycoprotein
chr1_-_157841800 2.31 ENST00000368174.5
CD5 molecule like
chr5_+_42756811 2.30 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chr15_-_100341899 2.25 ENST00000568565.2
ENST00000268070.9
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr12_-_102480552 2.15 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr2_+_233671879 2.14 ENST00000354728.5
UDP glucuronosyltransferase family 1 member A9
chr6_+_32038382 2.14 ENST00000478281.5
ENST00000471671.4
ENST00000435122.3
ENST00000644719.2
cytochrome P450 family 21 subfamily A member 2
chr3_+_52779916 2.11 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chr14_-_105743032 2.09 ENST00000390548.6
ENST00000390549.6
ENST00000390542.6
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_31927510 2.08 ENST00000447952.6
complement C2
chr11_-_10568650 2.07 ENST00000256178.8
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_10568571 2.05 ENST00000529598.1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_102917114 2.04 ENST00000550978.6
phenylalanine hydroxylase
chr2_+_127423265 2.03 ENST00000402125.2
protein C, inactivator of coagulation factors Va and VIIIa
chr7_-_100641507 2.01 ENST00000431692.5
ENST00000223051.8
transferrin receptor 2
chr2_+_134838610 2.00 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr22_+_22409755 1.99 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr1_-_201399525 1.99 ENST00000367313.4
ladinin 1
chr9_+_113594118 1.97 ENST00000620489.1
regulator of G protein signaling 3
chr3_-_52826834 1.94 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr2_-_87825952 1.94 ENST00000398146.4
RANBP2 like and GRIP domain containing 2
chr11_+_75151095 1.94 ENST00000289575.10
ENST00000525650.5
ENST00000454962.6
solute carrier organic anion transporter family member 2B1
chr2_+_233691607 1.92 ENST00000373424.5
ENST00000441351.1
UDP glucuronosyltransferase family 1 member A6
chr2_-_89085787 1.92 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr9_+_27109393 1.91 ENST00000406359.8
TEK receptor tyrosine kinase
chr14_+_69398683 1.86 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr12_+_103587266 1.83 ENST00000388887.7
stabilin 2
chr14_-_105940235 1.80 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr1_-_206946448 1.78 ENST00000356495.5
polymeric immunoglobulin receptor
chr4_+_165378998 1.76 ENST00000402744.9
carboxypeptidase E
chr12_-_102480638 1.75 ENST00000392904.5
insulin like growth factor 1
chr18_+_24113341 1.72 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr2_+_119429889 1.72 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr14_-_106771020 1.66 ENST00000617374.2
immunoglobulin heavy variable 2-70
chr9_+_27109441 1.65 ENST00000519080.1
TEK receptor tyrosine kinase
chr2_+_113127588 1.65 ENST00000409930.4
interleukin 1 receptor antagonist
chr12_+_118136086 1.61 ENST00000261313.3
phosphatidylethanolamine binding protein 1
chr22_+_22431949 1.61 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_+_22357739 1.61 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr12_-_95996302 1.61 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr11_-_2903490 1.60 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr4_+_110476133 1.57 ENST00000265162.10
glutamyl aminopeptidase
chr2_-_88979016 1.57 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr14_-_22589157 1.57 ENST00000538631.1
ENST00000543337.1
ENST00000250498.9
defender against cell death 1
chr9_-_125241327 1.55 ENST00000324460.7
ENST00000680272.1
ENST00000680032.1
heat shock protein family A (Hsp70) member 5
chr2_-_89268506 1.54 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr6_-_24489565 1.54 ENST00000230036.2
glycosylphosphatidylinositol specific phospholipase D1
chr3_+_184380207 1.54 ENST00000450923.5
ENST00000348986.3
chordin
chr14_-_105626066 1.53 ENST00000641978.1
ENST00000390543.3
immunoglobulin heavy constant gamma 4 (G4m marker)
chr2_+_90220727 1.52 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr2_-_150487658 1.51 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr9_+_27109200 1.49 ENST00000380036.10
TEK receptor tyrosine kinase
chr2_+_89862438 1.49 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr3_+_184380047 1.44 ENST00000204604.5
chordin
chrX_+_124346544 1.44 ENST00000371139.9
SH2 domain containing 1A
chr22_+_22327298 1.43 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr11_-_57390636 1.42 ENST00000525955.1
ENST00000533605.5
ENST00000311862.10
proteoglycan 2, pro eosinophil major basic protein
chr17_-_36001549 1.41 ENST00000617897.2
C-C motif chemokine ligand 15
chr17_-_75878542 1.41 ENST00000254816.6
tripartite motif containing 47
chr22_+_22668286 1.40 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr17_+_14301069 1.38 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr4_+_39406917 1.38 ENST00000257408.5
klotho beta
chr11_-_5243644 1.35 ENST00000643122.1
hemoglobin subunit delta
chr7_+_116672187 1.35 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr5_+_151020438 1.35 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr6_-_3751703 1.34 ENST00000380283.5
PX domain containing 1
chr17_+_1771688 1.33 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr1_-_201399302 1.33 ENST00000633953.1
ENST00000391967.7
ladinin 1
chr2_+_20667136 1.33 ENST00000272224.5
growth differentiation factor 7
chr9_+_27109135 1.33 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr20_+_35615812 1.32 ENST00000679710.1
ENST00000374273.8
sperm associated antigen 4
chr22_+_22322452 1.31 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr11_+_70085413 1.31 ENST00000316296.9
ENST00000530676.5
anoctamin 1
chr14_-_106675544 1.31 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr10_+_94762673 1.27 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr12_-_14843517 1.27 ENST00000228936.6
ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
chr12_-_102480604 1.27 ENST00000392905.7
insulin like growth factor 1
chr3_+_50155024 1.26 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr1_+_171314171 1.26 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr3_-_120682215 1.24 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr12_+_52233235 1.24 ENST00000331817.6
keratin 7
chr17_+_42851167 1.24 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr12_+_56996151 1.23 ENST00000556850.1
G protein-coupled receptor 182
chr11_-_914774 1.23 ENST00000528154.1
ENST00000525840.1
chitinase domain containing 1
chr1_+_61404076 1.22 ENST00000357977.5
nuclear factor I A
chr19_-_7747511 1.22 ENST00000593660.5
ENST00000204801.12
ENST00000315591.12
ENST00000354397.10
ENST00000394161.9
ENST00000593821.5
ENST00000602261.5
ENST00000601256.1
ENST00000601951.5
ENST00000315599.12
CD209 molecule
chrX_+_17737443 1.20 ENST00000398080.5
ENST00000380045.7
ENST00000380043.7
ENST00000380041.8
Scm polycomb group protein like 1
chr11_-_57237183 1.20 ENST00000606794.1
apelin receptor
chr20_+_46709666 1.19 ENST00000486000.2
solute carrier family 2 member 10
chr19_-_3600581 1.17 ENST00000589966.1
thromboxane A2 receptor
chr11_-_2139382 1.17 ENST00000416167.7
insulin like growth factor 2
chr4_-_57110373 1.13 ENST00000295666.6
ENST00000514062.2
insulin like growth factor binding protein 7
chr3_+_188947199 1.12 ENST00000433971.5
tumor protein p63 regulated 1
chr3_+_100609594 1.11 ENST00000273352.8
adhesion G protein-coupled receptor G7
chr2_-_74529670 1.10 ENST00000377526.4
AUP1 lipid droplet regulating VLDL assembly factor
chr22_+_22343185 1.10 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr2_+_90234809 1.10 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr3_+_38346760 1.09 ENST00000427323.5
ENST00000207870.8
ENST00000650590.1
xylulokinase
chr3_+_186567403 1.06 ENST00000439351.5
DnaJ heat shock protein family (Hsp40) member B11
chr10_-_96271508 1.06 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr11_+_63369779 1.05 ENST00000279178.4
solute carrier family 22 member 9
chr22_+_22375984 1.05 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr3_+_185363129 1.04 ENST00000265026.8
mitogen-activated protein kinase kinase kinase 13
chr2_+_27496830 1.04 ENST00000264717.7
glucokinase regulator
chr7_-_41703062 1.03 ENST00000242208.5
inhibin subunit beta A
chr6_-_25930678 1.03 ENST00000377850.8
solute carrier family 17 member 2
chr17_+_1762052 1.02 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
serpin family F member 1
chr15_-_39920162 1.02 ENST00000299092.3
G protein-coupled receptor 176
chr3_-_150546403 1.02 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr21_-_38661694 1.01 ENST00000417133.6
ENST00000398910.5
ENST00000442448.5
ENST00000429727.6
ETS transcription factor ERG
chr15_+_80152978 1.01 ENST00000561421.6
ENST00000684363.1
fumarylacetoacetate hydrolase
chr2_-_136116165 1.01 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr10_-_11611754 1.01 ENST00000609104.5
USP6 N-terminal like
chr6_-_25930611 0.99 ENST00000360488.7
solute carrier family 17 member 2
chr12_+_55681647 0.99 ENST00000614691.1
methyltransferase like 7B
chr17_+_76540035 0.98 ENST00000592014.6
photoreceptor disc component
chr12_+_111766887 0.97 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr2_+_236569817 0.96 ENST00000272928.4
atypical chemokine receptor 3
chr16_+_8712943 0.96 ENST00000561870.5
ENST00000396600.6
4-aminobutyrate aminotransferase
chr13_+_93226787 0.96 ENST00000377047.9
glypican 6
chr15_+_96332432 0.96 ENST00000559679.1
ENST00000394171.6
nuclear receptor subfamily 2 group F member 2
chr10_+_113553039 0.95 ENST00000351270.4
hyaluronan binding protein 2
chr6_+_33200820 0.95 ENST00000374675.7
solute carrier family 39 member 7
chr2_+_233729042 0.95 ENST00000482026.6
UDP glucuronosyltransferase family 1 member A3
chr2_-_64144411 0.94 ENST00000358912.5
pellino E3 ubiquitin protein ligase 1
chr1_-_42766978 0.94 ENST00000372526.2
ENST00000236040.8
ENST00000296388.10
ENST00000397054.7
prolyl 3-hydroxylase 1
chr9_+_136662907 0.94 ENST00000308874.12
ENST00000406555.7
ENST00000492862.6
EGF like domain multiple 7
chr12_+_55681711 0.94 ENST00000394252.4
methyltransferase like 7B
chr9_-_109498251 0.92 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr3_-_64687992 0.90 ENST00000498707.5
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr22_+_22162155 0.89 ENST00000390284.2
immunoglobulin lambda variable 4-60
chr11_-_124762283 0.89 ENST00000444566.5
ENST00000278927.10
ENST00000435477.1
endothelial cell adhesion molecule
chr7_+_40134966 0.89 ENST00000401647.7
ENST00000628514.3
ENST00000335693.9
ENST00000416370.2
succinyl-CoA:glutarate-CoA transferase
chr3_+_50155305 0.88 ENST00000002829.8
ENST00000426511.5
semaphorin 3F
chr6_-_33329262 0.87 ENST00000494082.3
small integral membrane protein 40
chr3_-_123620571 0.86 ENST00000583087.5
myosin light chain kinase
chr1_-_12616762 0.85 ENST00000464917.5
dehydrogenase/reductase 3
chr11_-_118252279 0.84 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr12_-_11269696 0.83 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr1_-_8879170 0.83 ENST00000489867.2
enolase 1
chr8_+_30387064 0.83 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr10_+_119207560 0.83 ENST00000392870.3
G protein-coupled receptor kinase 5
chr19_-_54257217 0.82 ENST00000345866.10
ENST00000449561.3
leukocyte immunoglobulin like receptor B5
chr19_-_7747559 0.81 ENST00000394173.8
CD209 molecule
chrX_+_129779930 0.81 ENST00000356892.4
SAM and SH3 domain containing 3
chr1_+_212285383 0.81 ENST00000261461.7
protein phosphatase 2 regulatory subunit B'alpha
chr16_+_11965234 0.80 ENST00000562385.1
TNF receptor superfamily member 17
chr19_+_35115912 0.80 ENST00000603181.5
FXYD domain containing ion transport regulator 3
chr20_-_62367304 0.80 ENST00000252999.7
laminin subunit alpha 5
chrX_+_124346525 0.79 ENST00000360027.4
SH2 domain containing 1A
chr7_+_26291850 0.79 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr3_-_64687982 0.78 ENST00000459780.1
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr7_-_120857124 0.78 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr20_+_43558968 0.78 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chr1_-_109392893 0.78 ENST00000633956.1
sortilin 1
chr6_+_33200860 0.78 ENST00000374677.8
solute carrier family 39 member 7
chr15_-_39920248 0.78 ENST00000561100.2
G protein-coupled receptor 176

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 19.8 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
3.6 14.5 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
3.6 3.6 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
2.7 10.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
1.4 25.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.3 12.1 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
1.2 7.5 GO:0008218 bioluminescence(GO:0008218)
1.0 5.2 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 6.5 GO:0048014 Tie signaling pathway(GO:0048014)
0.7 2.0 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.6 6.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.6 1.8 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.6 8.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 2.0 GO:0046968 peptide antigen transport(GO:0046968)
0.5 2.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.5 5.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 2.7 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 5.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.4 2.5 GO:0070295 renal water absorption(GO:0070295)
0.4 2.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.4 1.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.4 1.5 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 3.1 GO:0033504 floor plate development(GO:0033504)
0.4 1.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.4 1.4 GO:0002215 defense response to nematode(GO:0002215)
0.4 8.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 1.8 GO:0030070 insulin processing(GO:0030070)
0.3 1.0 GO:0060279 positive regulation of ovulation(GO:0060279)
0.3 1.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 2.0 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 0.9 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.3 1.6 GO:1903891 regulation of ATF6-mediated unfolded protein response(GO:1903891)
0.3 2.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.3 41.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.3 0.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 2.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 0.8 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 0.7 GO:0046247 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 1.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 1.0 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.5 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.2 1.6 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 0.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 1.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 1.6 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.6 GO:0071650 negative regulation of interleukin-18 production(GO:0032701) negative regulation of cytokine activity(GO:0060302) negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.2 0.9 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.2 3.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.2 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 1.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.4 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 0.8 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 2.1 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 1.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.7 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.5 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.2 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.7 GO:0010193 response to ozone(GO:0010193)
0.2 1.9 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2 2.0 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 1.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 2.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 1.3 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 11.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 1.3 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.2 1.5 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.2 0.3 GO:0071288 cellular response to mercury ion(GO:0071288)
0.2 0.9 GO:0001554 luteolysis(GO:0001554)
0.2 0.5 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 1.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 4.4 GO:0015671 oxygen transport(GO:0015671)
0.1 1.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.1 GO:0051414 response to cortisol(GO:0051414)
0.1 1.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.4 GO:0071529 cementum mineralization(GO:0071529)
0.1 1.7 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.4 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 2.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 0.4 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 1.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.6 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.3 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.6 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.7 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 2.7 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.6 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.7 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:1903414 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.4 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.6 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.4 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.3 GO:0036047 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.1 0.7 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.8 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 4.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 2.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.6 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.6 GO:2000230 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 1.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.1 GO:0015747 urate transport(GO:0015747)
0.1 0.2 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.3 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.1 2.4 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.6 GO:0048539 bone marrow development(GO:0048539)
0.1 0.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.6 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 2.0 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 3.5 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 3.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.1 0.4 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.1 0.7 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 0.9 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.3 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.8 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 12.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.2 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.2 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.3 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 1.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 1.0 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.7 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 4.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.6 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.0 0.2 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 1.3 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.4 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.3 GO:0046102 inosine metabolic process(GO:0046102)
0.0 2.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 2.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.6 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 1.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.4 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 2.2 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.6 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 2.0 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0097503 sialylation(GO:0097503)
0.0 1.2 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.3 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 2.1 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0001971 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.3 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 1.2 GO:0006959 humoral immune response(GO:0006959)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.5 GO:0000305 response to oxygen radical(GO:0000305)
0.0 1.3 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 1.0 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.9 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 23.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.8 25.1 GO:0005579 membrane attack complex(GO:0005579)
1.0 4.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.9 2.7 GO:0036117 hyaluranon cable(GO:0036117)
0.7 14.9 GO:0042627 chylomicron(GO:0042627)
0.4 4.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 1.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 16.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 0.8 GO:0043259 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.3 0.8 GO:1990427 stereocilia tip link(GO:0002140) myosin VII complex(GO:0031477) stereocilia tip-link density(GO:1990427) upper tip-link density(GO:1990435)
0.3 5.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 31.5 GO:0072562 blood microparticle(GO:0072562)
0.2 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0070701 mucus layer(GO:0070701)
0.1 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 8.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.6 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.7 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.6 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.8 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 18.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 61.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.8 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 3.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 1.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.3 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.9 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.1 10.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.8 14.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.8 5.5 GO:0019862 IgA binding(GO:0019862)
0.7 2.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.6 1.9 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 2.7 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 8.9 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 1.2 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.4 1.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.4 1.2 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4 2.5 GO:0015254 glycerol channel activity(GO:0015254)
0.3 2.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.3 3.0 GO:0045545 syndecan binding(GO:0045545)
0.3 1.6 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3 0.6 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.3 1.1 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.3 0.8 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 1.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.7 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 2.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.2 0.9 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.2 1.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 13.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.4 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.6 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.2 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.9 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2 0.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.2 0.6 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 4.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.5 GO:0036332 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.2 6.2 GO:0001972 retinoic acid binding(GO:0001972)
0.2 28.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 0.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 1.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 3.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.6 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 0.8 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 0.5 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 1.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 3.3 GO:0019841 retinol binding(GO:0019841)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 31.2 GO:0003823 antigen binding(GO:0003823)
0.1 0.8 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 2.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.4 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 0.4 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 3.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.0 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 5.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.5 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 1.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.3 GO:0097689 iron channel activity(GO:0097689)
0.1 0.3 GO:0036054 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1 5.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 2.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 1.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 1.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 5.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.2 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 6.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 13.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 3.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 2.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338) pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.0 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 2.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 2.0 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.0 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.9 PID CD40 PATHWAY CD40/CD40L signaling
0.1 10.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 8.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 9.9 PID SHP2 PATHWAY SHP2 signaling
0.1 34.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 7.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 3.7 PID BMP PATHWAY BMP receptor signaling
0.0 2.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.2 PID AURORA B PATHWAY Aurora B signaling
0.0 1.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 23.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.9 44.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 8.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 7.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 5.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 8.5 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 1.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 9.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.0 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.7 REACTOME OPSINS Genes involved in Opsins
0.0 2.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 6.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.5 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation