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Illumina Body Map 2 (GSE30611)

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Results for MBD2

Z-value: 0.75

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Transcription factors associated with MBD2

Gene Symbol Gene ID Gene Info
ENSG00000134046.12 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MBD2hg38_v1_chr18_-_54224578_54224689-0.441.1e-02Click!

Activity profile of MBD2 motif

Sorted Z-values of MBD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17617326 1.43 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr4_-_6472548 1.17 ENST00000382599.9
protein phosphatase 2 regulatory subunit Bgamma
chr2_+_219434825 1.17 ENST00000312358.12
striated muscle enriched protein kinase
chr1_+_109466527 1.17 ENST00000369872.4
synaptophysin like 2
chr9_-_109498251 1.12 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr18_-_28177934 1.12 ENST00000676445.1
cadherin 2
chrX_+_69504320 1.10 ENST00000252338.5
family with sequence similarity 155 member B
chr10_-_17617235 1.07 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr11_-_46918522 1.03 ENST00000378623.6
ENST00000534404.1
LDL receptor related protein 4
chr17_-_39197696 1.02 ENST00000394310.7
ENST00000622445.4
ENST00000344140.5
calcium voltage-gated channel auxiliary subunit beta 1
chr7_-_51316754 1.01 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr3_-_142963663 0.99 ENST00000340634.6
progestin and adipoQ receptor family member 9
chr16_-_51151259 0.98 ENST00000251020.9
spalt like transcription factor 1
chr17_-_29622893 0.91 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr19_+_55283982 0.84 ENST00000309383.6
BR serine/threonine kinase 1
chr7_+_141074038 0.83 ENST00000565468.6
ENST00000610315.1
transmembrane protein 178B
chr18_+_50560070 0.81 ENST00000400384.7
ENST00000540640.3
ENST00000592595.5
mitogen-activated protein kinase 4
chr7_-_100895878 0.81 ENST00000419336.6
ENST00000241069.11
ENST00000411582.4
ENST00000302913.8
acetylcholinesterase (Cartwright blood group)
chr15_-_65422894 0.78 ENST00000352385.3
immunoglobulin superfamily DCC subclass member 4
chr10_+_115093331 0.73 ENST00000609571.5
ENST00000355044.8
ENST00000526946.5
attractin like 1
chr17_-_39197652 0.72 ENST00000394303.8
calcium voltage-gated channel auxiliary subunit beta 1
chr17_-_29622732 0.72 ENST00000683819.1
ENST00000492276.7
coronin 6
chr16_-_51151238 0.72 ENST00000566102.1
spalt like transcription factor 1
chr7_-_150978284 0.72 ENST00000262186.10
potassium voltage-gated channel subfamily H member 2
chr15_-_73753308 0.70 ENST00000569673.3
inhibitory synaptic factor 1
chr15_-_101489697 0.70 ENST00000611967.4
ENST00000615296.4
ENST00000611716.5
ENST00000618548.4
ENST00000619160.4
ENST00000622483.4
ENST00000559417.2
proprotein convertase subtilisin/kexin type 6
chr4_-_52659238 0.67 ENST00000451218.6
ENST00000441222.8
ubiquitin specific peptidase 46
chr16_-_81096163 0.64 ENST00000566566.2
ENST00000569885.6
ENST00000561801.2
ENST00000639689.1
ENST00000638948.1
ENST00000564536.2
ENST00000638192.1
ENST00000640345.1
glycine cleavage system protein H
novel protein
novel protein
chr1_-_231422261 0.62 ENST00000366641.4
egl-9 family hypoxia inducible factor 1
chr7_-_100896123 0.62 ENST00000428317.7
acetylcholinesterase (Cartwright blood group)
chr2_+_100820102 0.61 ENST00000335681.10
neuronal PAS domain protein 2
chr2_+_197804583 0.61 ENST00000428675.6
phospholipase C like 1 (inactive)
chr18_+_8609404 0.60 ENST00000649141.2
RAB12, member RAS oncogene family
chr7_+_74453790 0.60 ENST00000265755.7
ENST00000424337.7
ENST00000455841.6
GTF2I repeat domain containing 1
chr9_+_34989641 0.59 ENST00000453597.8
ENST00000312316.9
ENST00000458263.6
ENST00000537321.5
ENST00000682809.1
ENST00000684748.1
DnaJ heat shock protein family (Hsp40) member B5
chr17_-_6556447 0.59 ENST00000421306.7
PITPNM family member 3
chr1_-_31763866 0.58 ENST00000398547.5
adhesion G protein-coupled receptor B2
chr17_+_50561010 0.58 ENST00000360761.8
ENST00000354983.8
ENST00000352832.9
calcium voltage-gated channel subunit alpha1 G
chr15_-_73633234 0.57 ENST00000562924.5
ENST00000563691.5
ENST00000565325.5
neuroplastin
chr11_+_66258467 0.57 ENST00000394066.6
kinesin light chain 2
chr1_+_52142044 0.56 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr1_-_31764333 0.55 ENST00000398542.5
ENST00000373658.8
adhesion G protein-coupled receptor B2
chr6_+_125154189 0.55 ENST00000532429.5
ENST00000534199.5
TPD52 like 1
chr13_-_75482114 0.54 ENST00000377625.6
ENST00000431480.6
TBC1 domain family member 4
chr11_-_45665578 0.53 ENST00000308064.7
carbohydrate sulfotransferase 1
chr1_-_22143088 0.53 ENST00000290167.11
Wnt family member 4
chr22_+_19714675 0.53 ENST00000412544.5
septin 5
chr1_-_31764035 0.53 ENST00000373655.6
adhesion G protein-coupled receptor B2
chr13_-_75482151 0.52 ENST00000377636.8
TBC1 domain family member 4
chr14_+_52553273 0.52 ENST00000542169.6
ENST00000555622.1
G protein-coupled receptor 137C
chr6_-_46015607 0.52 ENST00000644878.1
ENST00000644324.1
ENST00000672327.1
chloride intracellular channel 5
chr22_+_28883564 0.52 ENST00000544604.7
zinc and ring finger 3
chrX_+_153687918 0.51 ENST00000253122.10
solute carrier family 6 member 8
chr6_+_89433164 0.51 ENST00000369408.9
ENST00000447838.6
ankyrin repeat domain 6
chr1_+_6785437 0.50 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr3_-_51967410 0.50 ENST00000461554.6
ENST00000483411.5
ENST00000461544.2
ENST00000355852.6
poly(rC) binding protein 4
chr6_+_89433127 0.50 ENST00000339746.9
ankyrin repeat domain 6
chr22_-_19431692 0.50 ENST00000340170.8
ENST00000263208.5
histone cell cycle regulator
chr2_+_42048012 0.50 ENST00000294964.6
protein kinase domain containing, cytoplasmic
chr9_+_100427254 0.49 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr2_+_238426920 0.49 ENST00000264607.9
ankyrin repeat and SOCS box containing 1
chr10_-_124744280 0.49 ENST00000337318.8
family with sequence similarity 53 member B
chr22_+_19714450 0.48 ENST00000455784.7
ENST00000406395.5
septin 5
chr20_-_3159844 0.47 ENST00000217173.7
ENST00000449731.1
ENST00000380266.4
U-box domain containing 5
FAST kinase domains 5
chr6_+_163414701 0.47 ENST00000361752.8
QKI, KH domain containing RNA binding
chr11_+_45146631 0.45 ENST00000534751.3
ENST00000683152.1
PR/SET domain 11
chr17_+_50560703 0.44 ENST00000359106.10
calcium voltage-gated channel subunit alpha1 G
chr14_-_77320741 0.44 ENST00000682795.1
ENST00000682247.1
protein O-mannosyltransferase 2
chr2_-_118014125 0.44 ENST00000319432.9
coiled-coil domain containing 93
chr14_-_23578756 0.43 ENST00000397118.7
ENST00000356300.9
junctophilin 4
chr11_-_34357994 0.43 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr20_-_44810539 0.43 ENST00000372851.8
regulating synaptic membrane exocytosis 4
chr1_-_247331743 0.42 ENST00000294753.8
ENST00000682384.1
zinc finger protein 496
chr19_+_36054879 0.42 ENST00000378860.8
ENST00000427823.3
ENST00000681542.1
ENST00000680321.1
ENST00000680359.1
ENST00000680403.1
ENST00000679714.1
ENST00000679682.1
ENST00000401500.7
ENST00000680564.1
WD repeat domain 62
chr16_+_70114306 0.41 ENST00000288050.9
ENST00000398122.7
ENST00000568530.5
pyruvate dehydrogenase phosphatase regulatory subunit
chr20_+_37903104 0.41 ENST00000373459.4
ENST00000373461.9
ENST00000448944.1
V-set and transmembrane domain containing 2 like
chr12_+_125186376 0.40 ENST00000682704.1
transmembrane protein 132B
chr2_-_118014035 0.40 ENST00000376300.7
coiled-coil domain containing 93
chr3_+_54122542 0.39 ENST00000415676.6
ENST00000474759.6
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr8_-_73747458 0.39 ENST00000518767.5
staufen double-stranded RNA binding protein 2
chr19_+_3359563 0.39 ENST00000589123.5
ENST00000395111.7
ENST00000586919.5
nuclear factor I C
chr11_-_18791563 0.39 ENST00000396168.1
protein tyrosine phosphatase non-receptor type 5
chr6_-_46015812 0.39 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr11_-_110296627 0.39 ENST00000533991.1
radixin
chr15_-_42491105 0.38 ENST00000565380.5
ENST00000564754.7
zinc finger protein 106
chr12_+_19129689 0.38 ENST00000429027.7
ENST00000540972.5
pleckstrin homology domain containing A5
chr11_-_27700472 0.38 ENST00000418212.5
ENST00000533246.5
brain derived neurotrophic factor
chr6_-_166308385 0.38 ENST00000322583.5
proline rich 18
chr1_+_6785518 0.38 ENST00000467404.6
calmodulin binding transcription activator 1
chr5_+_176810498 0.37 ENST00000509580.2
unc-5 netrin receptor A
chr18_-_76990002 0.37 ENST00000585201.5
myelin basic protein
chr9_+_135075520 0.37 ENST00000252854.8
olfactomedin 1
chr19_+_3366549 0.37 ENST00000341919.7
ENST00000590282.5
ENST00000443272.3
nuclear factor I C
chr15_-_73633310 0.36 ENST00000345330.9
neuroplastin
chr1_+_3624978 0.36 ENST00000378344.7
ENST00000344579.5
tumor protein p63 regulated 1 like
chr17_-_6556539 0.36 ENST00000262483.13
PITPNM family member 3
chr13_+_34942263 0.35 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr5_+_98773651 0.35 ENST00000513185.3
repulsive guidance molecule BMP co-receptor b
chr15_+_90001300 0.35 ENST00000268154.9
zinc finger protein 710
chr13_+_20703677 0.34 ENST00000682841.1
interleukin 17D
chr3_-_123449083 0.34 ENST00000462833.6
adenylate cyclase 5
chr17_+_76868396 0.34 ENST00000569840.7
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
chr11_-_18791768 0.33 ENST00000358540.7
protein tyrosine phosphatase non-receptor type 5
chr1_-_153946652 0.33 ENST00000361217.9
DENN domain containing 4B
chr11_-_27700447 0.33 ENST00000356660.9
brain derived neurotrophic factor
chr2_-_99489955 0.33 ENST00000393445.7
ENST00000258428.8
REV1 DNA directed polymerase
chr19_-_17334804 0.33 ENST00000630631.1
anoctamin 8
chr11_-_134412234 0.33 ENST00000312527.9
beta-1,3-glucuronyltransferase 1
chrX_-_63755032 0.33 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr17_+_29593468 0.32 ENST00000614878.4
ankyrin repeat domain 13B
chr1_-_35557378 0.32 ENST00000325722.8
ENST00000469892.5
KIAA0319 like
chr16_-_28063704 0.32 ENST00000447459.7
GSG1 like
chr1_-_53328053 0.32 ENST00000371454.6
ENST00000667377.1
ENST00000306052.12
ENST00000668448.1
LDL receptor related protein 8
chr19_+_5805018 0.32 ENST00000303212.3
neurturin
chr22_+_44024269 0.32 ENST00000338758.12
parvin beta
chr1_-_31239880 0.32 ENST00000373736.7
sodium/potassium transporting ATPase interacting 1
chr19_-_11197516 0.32 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr9_+_100427176 0.32 ENST00000398977.2
Myb/SANT DNA binding domain containing 3
chr14_+_73950489 0.32 ENST00000554320.1
coenzyme Q6, monooxygenase
chr17_+_76868410 0.32 ENST00000301618.8
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
chr3_-_197297523 0.32 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr12_+_55743283 0.32 ENST00000546799.1
growth differentiation factor 11
chr3_+_54122636 0.32 ENST00000288197.9
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr22_-_20016807 0.32 ENST00000263207.8
ARVCF delta catenin family member
chr12_-_42238261 0.32 ENST00000380790.4
YY1 associated factor 2
chr2_-_183038405 0.31 ENST00000361354.9
NCK associated protein 1
chr12_-_42238203 0.31 ENST00000327791.8
ENST00000534854.7
YY1 associated factor 2
chrX_+_153072454 0.31 ENST00000421798.5
PNMA family member 6A
chr1_-_154558650 0.31 ENST00000292211.5
ubiquitin conjugating enzyme E2 Q1
chr2_+_26970628 0.31 ENST00000233121.7
ENST00000405074.7
microtubule associated protein RP/EB family member 3
chr18_+_74597850 0.31 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr7_-_28958321 0.31 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr19_+_36054930 0.31 ENST00000679757.1
ENST00000270301.12
WD repeat domain 62
chr14_-_77320813 0.30 ENST00000682467.1
protein O-mannosyltransferase 2
chr13_+_21671067 0.30 ENST00000382353.6
fibroblast growth factor 9
chr10_+_124801799 0.30 ENST00000298492.6
abraxas 2, BRISC complex subunit
chr10_-_103855406 0.30 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr7_+_43112593 0.30 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr12_+_19129779 0.30 ENST00000539256.5
ENST00000299275.10
ENST00000538714.5
pleckstrin homology domain containing A5
chr20_+_62302896 0.30 ENST00000620230.4
ENST00000253003.7
adhesion regulating molecule 1
chr1_+_179025804 0.30 ENST00000440702.5
FAM20B glycosaminoglycan xylosylkinase
chrX_-_63755187 0.29 ENST00000635729.1
ENST00000623566.3
Cdc42 guanine nucleotide exchange factor 9
chr11_-_134411854 0.29 ENST00000392580.5
beta-1,3-glucuronyltransferase 1
chr22_+_43412008 0.29 ENST00000334209.9
ENST00000443721.2
metallophosphoesterase domain containing 1
chr2_+_84971093 0.29 ENST00000456682.1
ENST00000409785.9
potassium channel modulatory factor 1
chr8_+_135458027 0.29 ENST00000524199.5
KH RNA binding domain containing, signal transduction associated 3
chr2_+_238426994 0.29 ENST00000409297.1
ankyrin repeat and SOCS box containing 1
chr9_+_135075422 0.28 ENST00000371799.8
ENST00000277415.15
olfactomedin 1
chr12_+_120640552 0.28 ENST00000316803.7
calcium binding protein 1
chr6_-_90586883 0.28 ENST00000369325.7
ENST00000369327.7
mitogen-activated protein kinase kinase kinase 7
chr4_+_70704713 0.28 ENST00000417478.6
RUN and FYVE domain containing 3
chr1_+_43389889 0.28 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr14_+_52552830 0.28 ENST00000321662.11
G protein-coupled receptor 137C
chr1_-_1540350 0.28 ENST00000624426.1
ENST00000425828.1
ENST00000378733.9
transmembrane protein 240
chr16_-_10942443 0.28 ENST00000570440.2
ENST00000331808.5
Dexi homolog
chr10_-_121598396 0.28 ENST00000336553.10
ENST00000457416.6
fibroblast growth factor receptor 2
chr3_-_53046031 0.28 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr1_-_160070102 0.27 ENST00000638728.1
ENST00000637644.1
potassium inwardly rectifying channel subfamily J member 10
chr2_+_235494024 0.27 ENST00000304032.13
ENST00000409457.5
ENST00000336665.9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_+_71212524 0.27 ENST00000335350.10
unc-5 netrin receptor B
chr10_+_81875173 0.27 ENST00000372141.7
ENST00000404547.5
neuregulin 3
chr14_-_77320855 0.27 ENST00000556394.2
ENST00000261534.9
protein O-mannosyltransferase 2
chr15_+_92393841 0.27 ENST00000268164.8
ENST00000539113.5
ENST00000555434.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr14_+_73950252 0.27 ENST00000629426.2
coenzyme Q6, monooxygenase
chr1_-_150010675 0.27 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr9_+_35829217 0.27 ENST00000439587.6
ENST00000643932.2
ENST00000650015.1
ENST00000377991.9
transmembrane protein 8B
chr4_-_11428868 0.27 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr14_+_103385374 0.27 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
microtubule affinity regulating kinase 3
chr10_+_104641282 0.27 ENST00000369701.8
sortilin related VPS10 domain containing receptor 3
chr10_+_103493931 0.26 ENST00000369780.8
neuralized E3 ubiquitin protein ligase 1
chr3_-_48430045 0.26 ENST00000296440.11
plexin B1
chr5_+_133051983 0.26 ENST00000304858.7
ENST00000617074.4
ENST00000615899.1
heat shock protein family A (Hsp70) member 4
chrX_-_63754664 0.26 ENST00000677315.1
ENST00000636392.1
ENST00000637040.1
ENST00000637178.1
ENST00000637557.1
ENST00000636048.1
ENST00000638021.1
ENST00000672513.1
novel protein
Cdc42 guanine nucleotide exchange factor 9
chr9_-_137221323 0.26 ENST00000391553.2
ENST00000392827.2
ring finger protein 208
chr6_-_90587018 0.26 ENST00000369332.7
ENST00000369329.8
mitogen-activated protein kinase kinase kinase 7
chr3_+_196568611 0.26 ENST00000440469.1
ENST00000311630.7
F-box protein 45
chr1_-_160262540 0.25 ENST00000368074.6
DDB1 and CUL4 associated factor 8
chr2_+_109794263 0.25 ENST00000272454.10
RANBP2 like and GRIP domain containing 5
chr7_+_45574358 0.25 ENST00000297323.12
adenylate cyclase 1
chr4_-_139084191 0.25 ENST00000512627.1
E74 like ETS transcription factor 2
chr3_-_184017863 0.25 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr1_-_160070150 0.25 ENST00000644903.1
potassium inwardly rectifying channel subfamily J member 10
chr10_-_121598234 0.25 ENST00000369058.7
ENST00000369060.8
ENST00000359354.6
fibroblast growth factor receptor 2
chr11_-_110296605 0.25 ENST00000534683.1
ENST00000647231.1
ENST00000645495.2
radixin
chr8_-_12755457 0.25 ENST00000398246.8
LON peptidase N-terminal domain and ring finger 1
chr22_-_31346317 0.25 ENST00000266269.10
POZ/BTB and AT hook containing zinc finger 1
chr1_-_160262407 0.25 ENST00000419626.1
ENST00000610139.5
ENST00000475733.5
ENST00000407642.6
ENST00000368073.7
ENST00000326837.6
DDB1 and CUL4 associated factor 8
chr1_+_35557435 0.25 ENST00000373253.7
neurochondrin
chr16_+_74999003 0.25 ENST00000335325.9
ENST00000320619.10
zinc and ring finger 1
chr4_-_576278 0.24 ENST00000610212.3
transmembrane protein 271
chr16_+_22814154 0.24 ENST00000261374.4
heparan sulfate-glucosamine 3-sulfotransferase 2
chr3_-_18445565 0.24 ENST00000415069.5
SATB homeobox 1
chr7_+_138460238 0.24 ENST00000343526.9
tripartite motif containing 24
chr17_-_65561137 0.24 ENST00000580513.1
axin 2
chr1_+_4654601 0.24 ENST00000378191.5
adherens junctions associated protein 1
chr6_+_139028838 0.24 ENST00000461027.1
ABRA C-terminal like
chr9_-_127854636 0.24 ENST00000344849.4
ENST00000373203.9
endoglin
chr12_-_57430956 0.24 ENST00000347140.7
ENST00000402412.5
R3H domain containing 2
chr3_+_49554436 0.24 ENST00000296452.5
bassoon presynaptic cytomatrix protein
chr13_+_31199959 0.24 ENST00000343307.5
beta 3-glucosyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of MBD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.3 1.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 1.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.7 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.2 0.7 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 0.9 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.5 GO:2000224 renal vesicle induction(GO:0072034) positive regulation of steroid hormone biosynthetic process(GO:0090031) regulation of testosterone biosynthetic process(GO:2000224)
0.2 0.5 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.2 1.0 GO:0001757 somite specification(GO:0001757)
0.1 1.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.6 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 0.9 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.5 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.7 GO:0032902 nerve growth factor production(GO:0032902)
0.1 2.5 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.7 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 0.2 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.2 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.2 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 1.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.1 0.3 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.2 GO:0048561 establishment of organ orientation(GO:0048561)
0.1 0.4 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.5 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 1.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.2 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.7 GO:0008343 adult feeding behavior(GO:0008343)
0.0 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1903570 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.6 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.6 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 1.0 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.2 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0035262 positive regulation of luteinizing hormone secretion(GO:0033686) gonad morphogenesis(GO:0035262) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.4 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.6 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.5 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.8 GO:0030539 male genitalia development(GO:0030539)
0.0 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532) negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.8 GO:0098534 centriole assembly(GO:0098534)
0.0 0.2 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.8 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 1.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.3 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0072560 type B pancreatic cell maturation(GO:0072560)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.6 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.0 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.2 GO:0072563 endothelial microparticle(GO:0072563)
0.1 0.2 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0051286 cell tip(GO:0051286)
0.1 1.1 GO:0016600 flotillin complex(GO:0016600)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.7 GO:0010369 chromocenter(GO:0010369)
0.1 1.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 1.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 2.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0032302 MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:1990032 climbing fiber(GO:0044301) parallel fiber(GO:1990032)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.4 1.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.3 1.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.3 1.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 0.6 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 0.7 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 0.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 0.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.3 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 0.2 GO:0070546 cysteine-S-conjugate beta-lyase activity(GO:0047804) L-phenylalanine aminotransferase activity(GO:0070546)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 1.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0032143 double-strand/single-strand DNA junction binding(GO:0000406) single thymine insertion binding(GO:0032143) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.0 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016) guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.0 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation