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Illumina Body Map 2 (GSE30611)

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Results for MEF2B

Z-value: 1.56

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Transcription factors associated with MEF2B

Gene Symbol Gene ID Gene Info
ENSG00000213999.17 myocyte enhancer factor 2B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MEF2Bhg38_v1_chr19_-_19192122_19192165-0.476.9e-03Click!

Activity profile of MEF2B motif

Sorted Z-values of MEF2B motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_26067622 13.30 ENST00000374272.4
tripartite motif containing 63
chr2_+_169509693 13.22 ENST00000284669.2
kelch like family member 41
chr12_-_110920568 11.60 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr12_-_48999363 11.24 ENST00000421952.3
dendrin
chr16_-_31428325 11.18 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chrX_-_21758097 10.73 ENST00000379494.4
small muscle protein X-linked
chr11_-_19201976 9.84 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr5_+_54455661 9.76 ENST00000302005.3
heat shock protein family B (small) member 3
chr2_+_88067818 9.72 ENST00000444564.2
ENST00000419482.7
SET and MYND domain containing 1
chr4_+_119135825 9.51 ENST00000307128.6
myozenin 2
chr2_-_210303608 9.49 ENST00000341685.8
myosin light chain 1
chr3_+_42685535 9.22 ENST00000287777.5
kelch like family member 40
chrX_-_21758021 8.56 ENST00000646008.1
small muscle protein X-linked
chr3_-_52452828 8.16 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr2_+_238138661 7.99 ENST00000409223.2
kelch like family member 30
chr2_+_167187283 7.72 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr8_+_2045037 7.60 ENST00000262113.9
myomesin 2
chr11_+_1839602 7.12 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr8_+_2045058 6.87 ENST00000523438.1
myomesin 2
chr14_-_93955577 6.70 ENST00000555507.5
ankyrin repeat and SOCS box containing 2
chr2_+_88067849 6.66 ENST00000438570.1
SET and MYND domain containing 1
chr7_-_113919000 6.61 ENST00000284601.4
protein phosphatase 1 regulatory subunit 3A
chr11_+_1838970 6.59 ENST00000381911.6
troponin I2, fast skeletal type
chr2_+_167187364 6.58 ENST00000672671.1
xin actin binding repeat containing 2
chr6_-_123636923 6.56 ENST00000334268.9
triadin
chr1_+_167094049 6.53 ENST00000361200.7
serine/threonine/tyrosine interacting like 2
chr3_-_39192584 6.15 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr11_+_1839452 6.06 ENST00000381906.5
troponin I2, fast skeletal type
chr16_+_31214088 5.99 ENST00000613872.1
tripartite motif containing 72
chr15_+_42359454 5.90 ENST00000349748.8
ENST00000318023.11
ENST00000397163.8
calpain 3
chr5_+_191477 5.87 ENST00000328278.4
leucine rich repeat containing 14B
chr16_+_31214111 5.80 ENST00000322122.8
tripartite motif containing 72
chr10_-_73655984 5.20 ENST00000394810.3
synaptopodin 2 like
chr14_-_93955258 5.19 ENST00000556062.5
ankyrin repeat and SOCS box containing 2
chr11_-_19202004 5.13 ENST00000648719.1
cysteine and glycine rich protein 3
chr5_-_16508812 5.09 ENST00000683414.1
reticulophagy regulator 1
chr3_+_179653032 5.08 ENST00000680587.1
ENST00000681064.1
ENST00000263966.8
ENST00000681358.1
ENST00000679749.1
ubiquitin specific peptidase 13
chr12_+_119178920 5.07 ENST00000281938.7
heat shock protein family B (small) member 8
chr5_-_16508990 5.01 ENST00000399793.6
reticulophagy regulator 1
chr12_-_110920710 4.96 ENST00000546404.1
myosin light chain 2
chr12_+_119178953 4.93 ENST00000674542.1
heat shock protein family B (small) member 8
chr3_+_179653129 4.91 ENST00000680008.1
ubiquitin specific peptidase 13
chr15_+_84817346 4.90 ENST00000258888.6
alpha kinase 3
chr5_-_16508788 4.76 ENST00000682142.1
reticulophagy regulator 1
chr5_-_16508858 4.76 ENST00000684456.1
reticulophagy regulator 1
chr6_-_123636906 4.75 ENST00000628709.2
triadin
chr17_-_9791586 4.73 ENST00000571134.2
dehydrogenase/reductase 7C
chr5_-_16508951 4.64 ENST00000682628.1
reticulophagy regulator 1
chr1_-_146021724 4.58 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr8_-_123653794 4.57 ENST00000684634.1
kelch like family member 38
chr17_+_7281711 4.54 ENST00000317370.13
ENST00000571308.5
solute carrier family 2 member 4
chr15_+_42359577 4.48 ENST00000357568.8
calpain 3
chr19_-_39834127 4.37 ENST00000601972.1
ENST00000430012.6
ENST00000323039.10
ENST00000348817.7
dual specificity tyrosine phosphorylation regulated kinase 1B
chr17_-_29140373 4.34 ENST00000533420.3
myosin XVIIIA
chrX_-_64230600 4.29 ENST00000362002.3
ankyrin repeat and SOCS box containing 12
chr2_+_219434825 4.27 ENST00000312358.12
striated muscle enriched protein kinase
chrX_-_15314543 3.61 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr18_-_3219849 3.52 ENST00000261606.11
myomesin 1
chr6_-_123636966 3.50 ENST00000542443.5
triadin
chr1_-_115768702 3.45 ENST00000261448.6
calsequestrin 2
chr18_-_3219961 3.44 ENST00000356443.9
myomesin 1
chr10_-_67696115 3.42 ENST00000433211.7
catenin alpha 3
chr1_-_23424692 3.38 ENST00000374601.7
ENST00000450454.7
transcription elongation factor A3
chr3_+_159852933 3.19 ENST00000482804.1
schwannomin interacting protein 1
chr22_-_50578417 3.13 ENST00000312108.12
ENST00000395650.6
carnitine palmitoyltransferase 1B
chr1_-_23424618 3.02 ENST00000476978.2
transcription elongation factor A3
chr3_-_57292676 3.01 ENST00000389601.3
ENST00000487349.6
ankyrin repeat and SOCS box containing 14
chr3_-_192727500 2.88 ENST00000430714.5
ENST00000418610.1
ENST00000445105.7
ENST00000684728.1
ENST00000448795.5
ENST00000683935.1
ENST00000684282.1
ENST00000683451.1
fibroblast growth factor 12
chr9_+_97501622 2.64 ENST00000259365.9
tropomodulin 1
chr10_-_75073627 2.63 ENST00000338487.6
dual specificity phosphatase 29
chr20_+_45407207 2.49 ENST00000372712.6
dysbindin domain containing 2
chr17_+_44170695 2.39 ENST00000293414.6
ankyrin repeat and SOCS box containing 16
chr14_+_24132050 2.33 ENST00000559294.1
fat storage inducing transmembrane protein 1
chr19_-_39833615 2.26 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr20_+_10218948 2.24 ENST00000430336.1
synaptosome associated protein 25
chr3_+_35642159 2.20 ENST00000187397.8
cAMP regulated phosphoprotein 21
chr14_-_70080180 2.15 ENST00000394330.6
ENST00000533541.1
ENST00000216568.11
solute carrier family 8 member A3
chr3_+_127915226 2.12 ENST00000405109.5
kelch repeat and BTB domain containing 12
chr7_+_143316105 2.10 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr10_-_95441015 2.05 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr17_-_44111253 2.01 ENST00000591714.5
histone deacetylase 5
chrX_-_143635081 1.99 ENST00000338017.8
SLIT and NTRK like family member 4
chr12_+_78863962 1.98 ENST00000393240.7
synaptotagmin 1
chr5_+_156326735 1.94 ENST00000435422.7
sarcoglycan delta
chr2_-_219253145 1.89 ENST00000456818.5
ENST00000447205.1
tubulin alpha 4a
chr9_-_83267230 1.87 ENST00000328788.5
FERM domain containing 3
chr11_-_47352693 1.85 ENST00000256993.8
ENST00000399249.6
ENST00000545968.6
myosin binding protein C3
chr5_-_88883701 1.81 ENST00000636998.1
myocyte enhancer factor 2C
chr3_+_127915469 1.79 ENST00000407609.7
kelch repeat and BTB domain containing 12
chr20_+_10218808 1.63 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr8_+_141417902 1.60 ENST00000681443.1
protein tyrosine phosphatase 4A3
chr14_-_20436161 1.46 ENST00000636854.3
kelch like family member 33
chr5_-_161547735 1.35 ENST00000675773.1
ENST00000274547.7
gamma-aminobutyric acid type A receptor subunit beta2
chr1_-_156490599 1.28 ENST00000360595.7
myocyte enhancer factor 2D
chr13_+_38687068 1.25 ENST00000280481.9
FRAS1 related extracellular matrix 2
chrX_-_139222777 1.22 ENST00000448673.1
fibroblast growth factor 13
chr14_-_21025000 1.20 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr4_+_41360759 1.18 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr18_-_50266481 1.10 ENST00000398545.5
cilia and flagella associated protein 53
chr3_+_54123452 1.07 ENST00000620722.4
ENST00000490478.5
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr14_-_21025490 1.04 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr17_-_44123628 1.04 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
histone deacetylase 5
chr12_+_25052663 0.97 ENST00000556887.5
inositol 1,4,5-triphosphate receptor associated 2
chr4_+_44678412 0.93 ENST00000281543.6
GTP binding elongation factor GUF1
chr12_+_25052694 0.86 ENST00000554942.5
inositol 1,4,5-triphosphate receptor associated 2
chr10_+_84424919 0.85 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr12_+_52037232 0.83 ENST00000553200.1
nuclear receptor subfamily 4 group A member 1
chr1_+_170664121 0.82 ENST00000239461.11
paired related homeobox 1
chr10_+_116590956 0.76 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr17_-_44123590 0.71 ENST00000336057.9
histone deacetylase 5
chr8_-_27258386 0.66 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chrX_+_71301742 0.64 ENST00000373829.8
ENST00000538820.1
integrin subunit beta 1 binding protein 2
chr10_+_116591010 0.62 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chr20_-_63951122 0.60 ENST00000369908.9
uridine-cytidine kinase 1 like 1
chr10_+_84425148 0.59 ENST00000493409.5
coiled-coil serine rich protein 2
chr17_-_29140400 0.58 ENST00000528564.2
myosin XVIIIA
chr17_+_20155989 0.53 ENST00000395530.6
ENST00000581399.6
ENST00000679819.1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_-_145910031 0.50 ENST00000369304.8
integrin subunit alpha 10
chr20_+_59676661 0.48 ENST00000355648.8
phosphatase and actin regulator 3
chr1_-_145910066 0.43 ENST00000539363.2
integrin subunit alpha 10
chr8_-_27258414 0.43 ENST00000523048.5
stathmin 4
chr1_-_145962581 0.42 ENST00000619813.1
ankyrin repeat domain 34A
chr13_-_44437214 0.39 ENST00000622051.1
TSC22 domain family member 1
chr10_+_116590407 0.33 ENST00000531984.5
pancreatic lipase related protein 1
chr11_+_72223688 0.28 ENST00000540973.1
inositol polyphosphate phosphatase like 1
chr20_+_58907981 0.28 ENST00000656419.1
GNAS complex locus
chr1_-_145962955 0.26 ENST00000619519.1
ankyrin repeat domain 34A
chr4_-_106368772 0.25 ENST00000638719.4
GIMAP family P-loop NTPase domain containing 1
chr1_+_212608628 0.23 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr3_+_8501807 0.19 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr12_-_7747339 0.15 ENST00000543765.1
ENST00000360345.8
ENST00000540085.5
C-type lectin domain family 4 member C
chr1_-_150720842 0.15 ENST00000442853.5
ENST00000368995.8
ENST00000322343.11
ENST00000361824.7
HORMA domain containing 1
chr1_+_160081529 0.14 ENST00000368088.4
potassium inwardly rectifying channel subfamily J member 9
chr7_+_87152599 0.14 ENST00000579592.5
ENST00000434534.5
cyclin D binding myb like transcription factor 1
chr1_+_76867469 0.12 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr15_+_68054308 0.11 ENST00000249636.11
protein inhibitor of activated STAT 1
chr22_+_19719435 0.09 ENST00000395109.6
septin 5
chr7_-_37449174 0.07 ENST00000445322.1
ENST00000448602.5
engulfment and cell motility 1
chr1_-_150720829 0.06 ENST00000368987.5
HORMA domain containing 1
chr14_-_21537064 0.05 ENST00000541965.1
spalt like transcription factor 2
chr5_-_132011580 0.04 ENST00000651250.1
ENST00000434099.6
ENST00000296869.9
ENST00000651356.1
ENST00000651883.2
acyl-CoA synthetase long chain family member 6
chr6_+_27957241 0.02 ENST00000244623.1
olfactory receptor family 2 subfamily B member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of MEF2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 24.3 GO:0061709 reticulophagy(GO:0061709)
3.0 14.8 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
2.7 21.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
2.5 10.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
2.2 13.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.0 8.2 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
1.5 9.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
1.5 15.0 GO:0035995 detection of muscle stretch(GO:0035995)
1.3 16.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.0 10.4 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
1.0 4.9 GO:1903028 positive regulation of opsonization(GO:1903028)
1.0 11.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.0 3.9 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.9 13.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.7 2.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.6 1.8 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.5 3.5 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 11.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 31.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.4 18.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 3.4 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3 2.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 2.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 2.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 1.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 13.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 13.6 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 3.7 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.1 3.1 GO:0006853 carnitine shuttle(GO:0006853)
0.1 2.2 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 2.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 6.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 4.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.6 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 18.7 GO:0006941 striated muscle contraction(GO:0006941)
0.1 4.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 6.8 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 0.2 GO:0051598 meiotic recombination checkpoint(GO:0051598)
0.1 1.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 10.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 5.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.0 3.8 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 3.7 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 29.3 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 2.4 GO:0060047 heart contraction(GO:0060047)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 19.3 GO:0005927 muscle tendon junction(GO:0005927)
2.2 8.8 GO:0005863 striated muscle myosin thick filament(GO:0005863)
1.4 16.6 GO:0097512 cardiac myofibril(GO:0097512)
1.4 8.2 GO:1990584 cardiac Troponin complex(GO:1990584)
1.3 19.8 GO:0005861 troponin complex(GO:0005861)
1.3 18.3 GO:0030314 junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
1.0 11.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.6 41.0 GO:0031430 M band(GO:0031430)
0.6 11.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.6 3.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 11.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 2.1 GO:0005899 insulin receptor complex(GO:0005899)
0.4 4.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 9.5 GO:0005859 muscle myosin complex(GO:0005859)
0.3 9.2 GO:0031672 A band(GO:0031672)
0.3 3.4 GO:0005916 fascia adherens(GO:0005916)
0.3 24.3 GO:0005801 cis-Golgi network(GO:0005801)
0.2 2.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 54.8 GO:0030018 Z disc(GO:0030018)
0.2 17.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 0.9 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 4.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 10.6 GO:0042383 sarcolemma(GO:0042383)
0.0 3.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 4.4 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 27.9 GO:0031014 troponin T binding(GO:0031014)
1.4 24.5 GO:0031433 telethonin binding(GO:0031433)
1.2 10.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.9 21.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.9 25.5 GO:0031432 titin binding(GO:0031432)
0.7 16.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 3.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 3.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 3.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 11.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 14.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 4.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 11.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 2.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 16.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 1.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2 4.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 2.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.9 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 8.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 3.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 56.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 6.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 4.9 GO:0043531 ADP binding(GO:0043531)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 15.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 16.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 5.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID INSULIN PATHWAY Insulin Pathway
0.0 1.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 56.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 5.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 4.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 35.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 3.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation