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Illumina Body Map 2 (GSE30611)
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Results for MEF2D_MEF2A
Z-value: 5.45
Motif logo
Transcription factors associated with MEF2D_MEF2A
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MEF2D
|
ENSG00000116604.18 | myocyte enhancer factor 2D |
|
MEF2A
|
ENSG00000068305.17 | myocyte enhancer factor 2A |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MEF2A | hg38_v1_chr15_+_99566066_99566087 | 0.50 | 3.7e-03 | Click! |
| MEF2D | hg38_v1_chr1_-_156490599_156490625 | 0.43 | 1.3e-02 | Click! |
Activity profile of MEF2D_MEF2A motif
Sorted Z-values of MEF2D_MEF2A motif
Network of associatons between targets according to the STRING database.
First level regulatory network of MEF2D_MEF2A
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 35.1 | 175.4 | GO:1901846 | positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846) |
| 20.8 | 207.6 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 16.3 | 130.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 11.5 | 46.0 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 10.4 | 31.2 | GO:1903280 | negative regulation of calcium:sodium antiporter activity(GO:1903280) |
| 8.1 | 65.2 | GO:0061709 | reticulophagy(GO:0061709) |
| 7.9 | 70.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 7.4 | 44.3 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
| 7.2 | 94.1 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 7.1 | 85.1 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 6.4 | 32.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 6.2 | 24.9 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 5.0 | 24.8 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 4.8 | 48.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 4.7 | 18.8 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 3.6 | 40.0 | GO:0032264 | IMP salvage(GO:0032264) |
| 3.5 | 41.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 3.4 | 20.4 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 3.3 | 23.2 | GO:0010731 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 3.3 | 234.8 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 3.1 | 46.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 3.0 | 12.2 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 3.0 | 18.1 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 2.7 | 16.5 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 2.7 | 16.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 2.6 | 33.2 | GO:0036309 | protein localization to M-band(GO:0036309) |
| 2.5 | 67.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 2.5 | 10.0 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 2.5 | 14.9 | GO:0015853 | adenine transport(GO:0015853) |
| 2.2 | 30.6 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 2.1 | 101.2 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 2.0 | 20.4 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 1.9 | 17.2 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 1.7 | 27.4 | GO:0060297 | regulation of sarcomere organization(GO:0060297) |
| 1.7 | 5.0 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 1.7 | 5.0 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 1.6 | 17.3 | GO:0046087 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 1.5 | 7.7 | GO:0044855 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 1.4 | 4.2 | GO:0070256 | negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 1.2 | 8.5 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 1.2 | 7.3 | GO:0003139 | secondary heart field specification(GO:0003139) |
| 1.2 | 5.9 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 1.1 | 21.7 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 1.1 | 12.4 | GO:0071286 | cellular response to magnesium ion(GO:0071286) |
| 1.1 | 3.2 | GO:1990764 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 1.1 | 2.1 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 1.1 | 117.0 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 1.0 | 36.7 | GO:0045214 | sarcomere organization(GO:0045214) |
| 1.0 | 19.9 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 1.0 | 32.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 1.0 | 93.3 | GO:0055008 | cardiac muscle tissue morphogenesis(GO:0055008) |
| 1.0 | 18.4 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 1.0 | 12.4 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 0.9 | 5.6 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.8 | 20.4 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.8 | 3.3 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 0.8 | 3.2 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.8 | 13.8 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.7 | 5.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.7 | 9.5 | GO:0009128 | purine nucleoside monophosphate catabolic process(GO:0009128) |
| 0.7 | 3.5 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.7 | 6.1 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.7 | 7.2 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.6 | 87.1 | GO:0005977 | glycogen metabolic process(GO:0005977) |
| 0.6 | 26.1 | GO:0010880 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) |
| 0.6 | 5.0 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.6 | 12.5 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.6 | 31.1 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
| 0.6 | 3.6 | GO:0015862 | uridine transport(GO:0015862) |
| 0.6 | 24.6 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.6 | 1.7 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 0.6 | 5.6 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.6 | 2.2 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.6 | 8.9 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.5 | 3.3 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.5 | 11.7 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.5 | 22.9 | GO:0061620 | NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.5 | 1.0 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.5 | 2.6 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.5 | 3.5 | GO:0032484 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.5 | 4.9 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.5 | 3.8 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.5 | 10.4 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.5 | 88.7 | GO:0006941 | striated muscle contraction(GO:0006941) |
| 0.5 | 2.3 | GO:0033058 | directional locomotion(GO:0033058) |
| 0.5 | 1.9 | GO:1903984 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
| 0.5 | 5.4 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.4 | 17.5 | GO:0030239 | myofibril assembly(GO:0030239) |
| 0.4 | 8.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.4 | 17.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.4 | 1.7 | GO:0002188 | formation of cytoplasmic translation initiation complex(GO:0001732) translation reinitiation(GO:0002188) |
| 0.4 | 2.1 | GO:1903525 | regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527) |
| 0.4 | 6.1 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 3.4 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.3 | 4.8 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.3 | 1.6 | GO:0006574 | valine catabolic process(GO:0006574) |
| 0.2 | 4.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.2 | 21.9 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.2 | 1.2 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.2 | 20.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.2 | 5.9 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 3.5 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.2 | 160.7 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.2 | 3.6 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.2 | 4.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.2 | 5.6 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.2 | 23.4 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.2 | 25.0 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.2 | 11.4 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.2 | 7.0 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.2 | 2.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.1 | 3.5 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
| 0.1 | 2.9 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.1 | 2.2 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.1 | 15.6 | GO:0061337 | cardiac conduction(GO:0061337) |
| 0.1 | 3.8 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.1 | 22.3 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.1 | 10.0 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 0.8 | GO:0007512 | adult heart development(GO:0007512) |
| 0.1 | 5.8 | GO:0070570 | regulation of neuron projection regeneration(GO:0070570) |
| 0.1 | 1.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.1 | 1.8 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.1 | 9.3 | GO:0060047 | heart contraction(GO:0060047) |
| 0.1 | 0.4 | GO:0036367 | adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367) |
| 0.1 | 15.8 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.1 | 1.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.1 | 2.2 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 1.2 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.1 | 23.7 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.1 | 2.2 | GO:0010991 | regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 0.8 | GO:0030222 | eosinophil differentiation(GO:0030222) |
| 0.1 | 2.0 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 1.0 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.1 | 0.9 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.1 | 2.0 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.1 | 1.3 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 1.4 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.1 | 16.2 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.1 | 5.6 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
| 0.1 | 4.6 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 3.1 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 0.4 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.1 | 64.4 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.1 | 2.9 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 2.3 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.1 | 1.8 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 1.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.1 | 7.5 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.1 | 0.5 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.0 | 1.6 | GO:0048265 | response to pain(GO:0048265) |
| 0.0 | 1.9 | GO:0015682 | ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512) |
| 0.0 | 9.1 | GO:0071805 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 1.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.5 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.0 | 4.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 1.5 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 1.0 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.0 | 2.6 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 1.0 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.0 | 0.3 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.0 | 2.5 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.0 | 0.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.1 | GO:1901529 | positive regulation of anion channel activity(GO:1901529) |
| 0.0 | 0.6 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 23.8 | 142.7 | GO:0005927 | muscle tendon junction(GO:0005927) |
| 19.2 | 76.9 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 16.7 | 233.8 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 9.2 | 110.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 7.7 | 46.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 6.9 | 186.3 | GO:0032982 | myosin filament(GO:0032982) |
| 6.5 | 97.9 | GO:0005861 | troponin complex(GO:0005861) |
| 4.5 | 13.6 | GO:1990844 | subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844) |
| 3.8 | 67.6 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 3.6 | 172.8 | GO:0031430 | M band(GO:0031430) |
| 3.2 | 22.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 3.1 | 85.9 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 2.3 | 27.3 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 2.2 | 638.3 | GO:0031674 | I band(GO:0031674) |
| 2.1 | 54.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 1.7 | 19.1 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 1.7 | 20.4 | GO:0005916 | fascia adherens(GO:0005916) |
| 1.3 | 11.7 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 1.2 | 13.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 1.1 | 21.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 1.0 | 5.0 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.9 | 24.4 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.8 | 94.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.8 | 8.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.8 | 68.9 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.8 | 12.9 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.7 | 47.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.6 | 39.0 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.6 | 9.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.6 | 1.9 | GO:1990622 | CHOP-ATF3 complex(GO:1990622) |
| 0.5 | 25.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.5 | 21.3 | GO:0016528 | sarcoplasm(GO:0016528) |
| 0.4 | 2.5 | GO:0034680 | integrin alpha10-beta1 complex(GO:0034680) |
| 0.4 | 1.7 | GO:0043614 | multi-eIF complex(GO:0043614) |
| 0.3 | 3.5 | GO:0016589 | NURF complex(GO:0016589) |
| 0.3 | 43.1 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.3 | 15.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 13.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.3 | 10.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 3.2 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 5.9 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 93.1 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.2 | 2.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 4.7 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.2 | 10.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 28.2 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 15.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 4.5 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.1 | 0.3 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.1 | 24.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 2.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.9 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.1 | 3.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 7.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 13.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 18.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 11.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 2.6 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 1.6 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 17.4 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.1 | 0.5 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 6.3 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 1.6 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 1.4 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.8 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 22.1 | GO:0015629 | actin cytoskeleton(GO:0015629) |
| 0.0 | 5.1 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 16.8 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 7.1 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 2.6 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 5.7 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 4.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 1.2 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.0 | GO:0005592 | collagen type XI trimer(GO:0005592) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 14.1 | 113.1 | GO:0051373 | FATZ binding(GO:0051373) |
| 10.9 | 131.1 | GO:0031433 | telethonin binding(GO:0031433) |
| 10.6 | 362.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 7.8 | 31.2 | GO:0050262 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 7.4 | 104.2 | GO:0031014 | troponin T binding(GO:0031014) |
| 6.4 | 146.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 5.9 | 140.6 | GO:0031432 | titin binding(GO:0031432) |
| 5.7 | 22.8 | GO:0030172 | troponin C binding(GO:0030172) |
| 5.4 | 16.2 | GO:0070538 | oleic acid binding(GO:0070538) |
| 4.7 | 18.8 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 4.1 | 20.4 | GO:0004082 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 3.8 | 15.2 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 3.7 | 29.8 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 3.7 | 14.9 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 3.6 | 46.4 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 3.2 | 19.1 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 3.1 | 24.9 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 3.0 | 69.3 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 2.5 | 20.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 2.2 | 19.9 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 2.0 | 20.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 2.0 | 95.6 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 2.0 | 12.2 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 1.9 | 67.6 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 1.9 | 22.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.7 | 17.3 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 1.7 | 31.2 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 1.2 | 13.4 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.2 | 8.5 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 1.1 | 11.4 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 1.1 | 24.8 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 1.1 | 11.0 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 1.1 | 5.4 | GO:0004572 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572) |
| 1.0 | 7.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 1.0 | 91.9 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.9 | 91.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.8 | 4.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.8 | 3.3 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.8 | 7.0 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.8 | 21.0 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.7 | 41.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.7 | 5.0 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.7 | 7.7 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.7 | 11.1 | GO:0042805 | actinin binding(GO:0042805) |
| 0.7 | 12.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.6 | 3.8 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.6 | 2.9 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.6 | 5.0 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.5 | 11.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.5 | 8.2 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.5 | 32.1 | GO:0043531 | ADP binding(GO:0043531) |
| 0.5 | 2.0 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.5 | 152.7 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.5 | 9.6 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.5 | 8.9 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.4 | 9.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.4 | 2.6 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.4 | 6.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.4 | 12.4 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.4 | 1.2 | GO:0046848 | hydroxyapatite binding(GO:0046848) |
| 0.4 | 278.8 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.4 | 2.1 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.4 | 3.5 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.3 | 1.0 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.3 | 1.6 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.3 | 7.0 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.3 | 2.9 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.3 | 15.4 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.3 | 2.5 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.3 | 4.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 3.3 | GO:0015250 | water channel activity(GO:0015250) |
| 0.2 | 3.5 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.2 | 4.7 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.2 | 3.7 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.2 | 1.4 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.2 | 185.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.2 | 15.0 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.2 | 21.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 5.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 26.1 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.2 | 2.0 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 1.5 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.1 | 0.5 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.1 | 2.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.1 | 3.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.1 | 13.8 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 4.5 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 13.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 15.1 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.1 | 3.3 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 3.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 2.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.1 | 0.7 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 8.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 0.3 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) |
| 0.1 | 4.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 2.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 5.9 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 1.3 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 27.9 | GO:0008022 | protein C-terminus binding(GO:0008022) |
| 0.1 | 0.3 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.1 | 1.0 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 0.4 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.1 | 0.3 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 0.1 | 2.9 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.1 | 0.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 2.3 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.1 | 13.5 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 1.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.0 | 3.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 1.5 | GO:0022832 | voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832) |
| 0.0 | 0.3 | GO:0004983 | neuropeptide Y receptor activity(GO:0004983) |
| 0.0 | 0.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 1.2 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.4 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 1.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 2.4 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 94.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.6 | 35.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.5 | 25.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.4 | 19.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.2 | 34.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 28.6 | PID FGF PATHWAY | FGF signaling pathway |
| 0.2 | 7.7 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.2 | 13.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 26.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.2 | 10.3 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.2 | 1.7 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.1 | 11.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.0 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 4.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 12.1 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 4.4 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 1.7 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 2.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.5 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 2.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 1.0 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 1.3 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.7 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 1.6 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.0 | 0.9 | PID MTOR 4PATHWAY | mTOR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 493.3 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 1.5 | 40.0 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 1.2 | 94.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.9 | 28.7 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.9 | 36.9 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.9 | 24.8 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.7 | 35.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.6 | 12.4 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.5 | 9.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.5 | 31.3 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.4 | 7.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.3 | 17.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.3 | 11.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.3 | 22.3 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.2 | 14.4 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.2 | 30.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 80.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 6.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.2 | 7.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 15.4 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 4.2 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 0.9 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 4.4 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 2.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 4.8 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.1 | 5.8 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.0 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 3.3 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.1 | 7.5 | REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | Genes involved in Glucagon signaling in metabolic regulation |
| 0.1 | 1.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 1.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 1.6 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 1.7 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 2.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 5.7 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.8 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 1.9 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 1.0 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 1.7 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 1.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 1.4 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.0 | 0.5 | REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.0 | 0.3 | REACTOME ARMS MEDIATED ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.0 | 0.8 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.8 | REACTOME DEFENSINS | Genes involved in Defensins |