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Illumina Body Map 2 (GSE30611)

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Results for MEIS3_TGIF2LX

Z-value: 1.03

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Transcription factors associated with MEIS3_TGIF2LX

Gene Symbol Gene ID Gene Info
ENSG00000105419.18 Meis homeobox 3
ENSG00000153779.11 TGFB induced factor homeobox 2 like X-linked

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2LXhg38_v1_chrX_+_89921903_899219560.115.5e-01Click!
MEIS3hg38_v1_chr19_-_47419490_47419538-0.105.9e-01Click!

Activity profile of MEIS3_TGIF2LX motif

Sorted Z-values of MEIS3_TGIF2LX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_47190013 4.29 ENST00000294338.7
PDZK1 interacting protein 1
chr17_+_42851167 3.80 ENST00000613571.1
ENST00000308423.7
amine oxidase copper containing 3
chr16_+_1240698 2.61 ENST00000561736.2
ENST00000338844.8
ENST00000461509.6
tryptase alpha/beta 1
chr16_-_1230089 2.56 ENST00000612142.1
ENST00000606293.5
tryptase beta 2
chr11_-_107719657 2.56 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr7_+_76510528 2.47 ENST00000334348.8
uroplakin 3B
chr7_-_27152561 2.37 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
novel transcript
homeobox A3
novel transcript
chr16_+_29778252 2.25 ENST00000400752.6
zymogen granule protein 16
chr1_+_86468902 2.01 ENST00000394711.2
chloride channel accessory 1
chr9_-_22009272 1.99 ENST00000380142.5
ENST00000276925.7
cyclin dependent kinase inhibitor 2B
chr11_-_76669985 1.98 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr1_-_155192867 1.79 ENST00000342482.8
ENST00000343256.9
ENST00000368389.6
ENST00000368390.7
ENST00000368396.8
ENST00000368398.7
ENST00000471283.5
ENST00000337604.6
ENST00000368392.7
ENST00000368393.7
ENST00000438413.5
ENST00000457295.6
ENST00000462215.5
ENST00000620103.4
ENST00000338684.9
ENST00000610359.4
ENST00000611571.4
ENST00000611577.4
ENST00000612778.4
ENST00000614519.4
ENST00000615517.4
mucin 1, cell surface associated
chr12_+_12891554 1.79 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr17_-_44268119 1.71 ENST00000399246.3
ENST00000262418.12
solute carrier family 4 member 1 (Diego blood group)
chr11_-_119317119 1.64 ENST00000264036.6
melanoma cell adhesion molecule
chr2_+_96536743 1.53 ENST00000673792.1
ENST00000357485.8
AT-rich interaction domain 5A
chr21_-_42315336 1.49 ENST00000398431.2
ENST00000518498.3
trefoil factor 3
chr2_+_96537254 1.49 ENST00000454558.2
AT-rich interaction domain 5A
chr17_-_35795592 1.43 ENST00000615136.4
ENST00000605424.6
ENST00000612672.1
matrix metallopeptidase 28
chr17_+_39626702 1.39 ENST00000580825.5
protein phosphatase 1 regulatory inhibitor subunit 1B
chr12_-_10849464 1.37 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr16_+_66376341 1.36 ENST00000562048.5
ENST00000568155.2
cadherin 5
chr17_-_41624541 1.34 ENST00000540235.5
ENST00000311208.13
keratin 17
chr2_+_89913982 1.27 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr1_-_153544997 1.21 ENST00000368715.5
S100 calcium binding protein A4
chr9_-_33447553 1.21 ENST00000645858.1
ENST00000297991.6
aquaporin 3 (Gill blood group)
chr16_+_1256059 1.18 ENST00000397534.6
ENST00000211076.5
tryptase delta 1
chr19_-_51027662 1.18 ENST00000594768.5
kallikrein related peptidase 11
chr18_-_55322334 1.15 ENST00000630720.3
transcription factor 4
chr21_+_29130630 1.14 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr5_+_115962467 1.11 ENST00000357872.9
ENST00000395528.6
laeverin
chr17_-_41624803 1.09 ENST00000463128.5
keratin 17
chr17_-_41624382 1.08 ENST00000577817.3
keratin 17
chr3_+_155083889 1.06 ENST00000680282.1
membrane metalloendopeptidase
chr1_+_99646025 1.06 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr17_+_39626944 1.03 ENST00000582680.5
ENST00000254079.9
protein phosphatase 1 regulatory inhibitor subunit 1B
chr19_-_51026593 1.03 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
kallikrein related peptidase 11
chr11_+_18266254 1.01 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr10_-_7619660 1.00 ENST00000613909.4
inter-alpha-trypsin inhibitor heavy chain 5
chr11_-_76670737 0.99 ENST00000260061.9
ENST00000404995.5
leucine rich repeat containing 32
chr19_-_51028015 0.99 ENST00000319720.11
kallikrein related peptidase 11
chr13_+_77535742 0.92 ENST00000377246.7
sciellin
chr13_+_77535681 0.92 ENST00000349847.4
sciellin
chr13_+_77535669 0.90 ENST00000535157.5
sciellin
chr3_+_155083523 0.90 ENST00000680057.1
membrane metalloendopeptidase
chr5_-_170389349 0.89 ENST00000274629.9
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr9_-_112890868 0.88 ENST00000374228.5
solute carrier family 46 member 2
chr1_+_45913647 0.87 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chr14_-_106627685 0.84 ENST00000390629.3
immunoglobulin heavy variable 4-59
chr2_+_89862438 0.81 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr19_-_51027954 0.81 ENST00000391804.7
kallikrein related peptidase 11
chr15_+_65045377 0.79 ENST00000334287.3
solute carrier family 51 subunit beta
chr3_-_49029378 0.78 ENST00000442157.2
ENST00000326739.9
ENST00000677010.1
ENST00000678724.1
ENST00000429182.6
inosine monophosphate dehydrogenase 2
chrX_+_136536099 0.77 ENST00000440515.5
ENST00000456412.1
vestigial like family member 1
chr2_+_90100235 0.76 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr19_+_1000419 0.73 ENST00000234389.3
glutamate ionotropic receptor NMDA type subunit 3B
chrX_-_11427725 0.72 ENST00000380736.5
Rho GTPase activating protein 6
chr4_-_186596770 0.71 ENST00000512772.5
FAT atypical cadherin 1
chr3_-_134029914 0.71 ENST00000493729.5
ENST00000310926.11
solute carrier organic anion transporter family member 2A1
chr5_+_151020438 0.71 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
glutathione peroxidase 3
chr11_-_35526024 0.70 ENST00000615849.4
peptidase domain containing associated with muscle regeneration 1
chr4_-_18021727 0.70 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr11_+_1099730 0.68 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chr9_-_92536645 0.68 ENST00000395534.2
extracellular matrix protein 2
chrX_-_13817027 0.65 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr1_-_183590596 0.63 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr21_+_29130961 0.63 ENST00000399925.5
MAP3K7 C-terminal like
chr19_+_18419374 0.63 ENST00000270061.12
single stranded DNA binding protein 4
chr11_+_102317492 0.62 ENST00000673846.1
baculoviral IAP repeat containing 3
chr9_+_34990250 0.62 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr13_-_38990824 0.61 ENST00000379631.9
stomatin like 3
chr9_-_83817632 0.60 ENST00000376365.7
ENST00000376371.7
G kinase anchoring protein 1
chr19_+_676385 0.60 ENST00000166139.9
follistatin like 3
chr7_+_76510516 0.60 ENST00000257632.9
uroplakin 3B
chr6_+_34236865 0.59 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr2_-_89117844 0.59 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr10_+_97589715 0.57 ENST00000370640.5
chromosome 10 open reading frame 62
chr1_-_183590439 0.57 ENST00000367535.8
neutrophil cytosolic factor 2
chr11_-_101129806 0.57 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr19_+_18419322 0.56 ENST00000348495.10
single stranded DNA binding protein 4
chr11_-_65557740 0.56 ENST00000526927.5
latent transforming growth factor beta binding protein 3
chr1_+_19596960 0.56 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr11_+_102317542 0.55 ENST00000532808.5
baculoviral IAP repeat containing 3
chr12_+_104064520 0.54 ENST00000229330.9
host cell factor C2
chr11_+_827545 0.53 ENST00000528542.6
calcium release activated channel regulator 2B
chr1_-_201112420 0.52 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr19_+_47256518 0.51 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr1_-_31798755 0.51 ENST00000452755.6
SPOC domain containing 1
chr7_+_134646798 0.50 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr1_+_45913583 0.50 ENST00000372008.6
microtubule associated serine/threonine kinase 2
chr9_+_132978687 0.50 ENST00000372122.4
ENST00000372123.5
growth factor independent 1B transcriptional repressor
chr18_+_3449817 0.50 ENST00000407501.6
TGFB induced factor homeobox 1
chr13_-_77919459 0.49 ENST00000643890.1
endothelin receptor type B
chr22_+_22668286 0.49 ENST00000390304.2
immunoglobulin lambda variable 3-27
chrX_+_23908006 0.49 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr13_-_38990856 0.49 ENST00000423210.1
stomatin like 3
chr1_+_81699665 0.48 ENST00000359929.7
adhesion G protein-coupled receptor L2
chr1_-_183590876 0.47 ENST00000367536.5
neutrophil cytosolic factor 2
chr2_-_217905445 0.47 ENST00000413554.5
tensin 1
chr3_-_64268161 0.47 ENST00000564377.6
prickle planar cell polarity protein 2
chr7_+_76510608 0.47 ENST00000394849.1
uroplakin 3B
chr11_+_828150 0.46 ENST00000450448.5
calcium release activated channel regulator 2B
chr11_+_68008542 0.46 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr12_-_50025394 0.46 ENST00000454520.6
ENST00000546595.5
ENST00000548824.5
ENST00000549777.5
ENST00000546723.5
ENST00000427314.6
ENST00000552157.5
ENST00000552310.5
ENST00000548644.5
ENST00000546786.5
ENST00000550149.5
ENST00000546764.5
ENST00000552004.2
ENST00000548320.5
ENST00000312377.10
ENST00000547905.5
ENST00000550651.5
ENST00000551145.5
ENST00000552921.5
Rac GTPase activating protein 1
chr1_-_201112451 0.46 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr3_+_29280945 0.45 ENST00000434693.6
RNA binding motif single stranded interacting protein 3
chr21_-_46323806 0.44 ENST00000397680.5
ENST00000445935.5
ENST00000291691.12
ENST00000397682.7
chromosome 21 open reading frame 58
chr17_-_19745602 0.44 ENST00000444455.5
ENST00000439102.6
aldehyde dehydrogenase 3 family member A1
chr4_-_183320267 0.44 ENST00000323319.7
claudin 22
chr18_+_3449620 0.44 ENST00000405385.7
TGFB induced factor homeobox 1
chr19_+_18419425 0.44 ENST00000601357.6
single stranded DNA binding protein 4
chr3_-_12841527 0.43 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
ribosomal protein L32
chr7_+_134646845 0.43 ENST00000344924.8
bisphosphoglycerate mutase
chr5_-_59586393 0.43 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chrX_-_118116746 0.43 ENST00000371882.5
ENST00000545703.5
ENST00000540167.5
kelch like family member 13
chr8_+_66043413 0.42 ENST00000522619.1
DnaJ heat shock protein family (Hsp40) member C5 beta
chr16_+_67326808 0.42 ENST00000329956.11
ENST00000569499.6
ENST00000561948.1
leucine rich repeat containing 36
chr2_+_188991663 0.41 ENST00000450867.1
collagen type III alpha 1 chain
chr11_-_2149603 0.41 ENST00000643349.1
novel protein
chr17_+_75093287 0.39 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chrX_+_17737443 0.39 ENST00000398080.5
ENST00000380045.7
ENST00000380043.7
ENST00000380041.8
Scm polycomb group protein like 1
chr3_-_187745460 0.39 ENST00000406870.7
BCL6 transcription repressor
chr10_+_122211175 0.39 ENST00000496913.6
transforming acidic coiled-coil containing protein 2
chr13_+_114179272 0.38 ENST00000646158.1
ENST00000636692.1
CFAP97 domain containing 2
chr1_-_2003808 0.37 ENST00000493964.5
cilia and flagella associated protein 74
chr12_-_25648544 0.37 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
lamin tail domain containing 1
chr2_+_24491860 0.37 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr11_-_78417788 0.36 ENST00000361507.5
GRB2 associated binding protein 2
chr19_-_8981342 0.36 ENST00000397910.8
mucin 16, cell surface associated
chr5_-_42887392 0.35 ENST00000514218.5
selenoprotein P
chr12_-_122730828 0.34 ENST00000432564.3
hydroxycarboxylic acid receptor 1
chr3_+_131026844 0.34 ENST00000510769.5
ENST00000383366.9
ENST00000510688.5
ENST00000511262.5
NIMA related kinase 11
chr5_+_15500172 0.34 ENST00000504595.2
F-box and leucine rich repeat protein 7
chr1_-_2003780 0.33 ENST00000682832.1
cilia and flagella associated protein 74
chr16_+_20806424 0.33 ENST00000568894.5
RNA exonuclease 5
chr1_+_201739864 0.32 ENST00000367295.5
neuron navigator 1
chr13_+_114179247 0.32 ENST00000635901.2
CFAP97 domain containing 2
chr10_-_87841336 0.32 ENST00000495903.1
ATPase family AAA domain containing 1
chr3_-_71305986 0.32 ENST00000647614.1
forkhead box P1
chr16_+_20806439 0.31 ENST00000568046.5
RNA exonuclease 5
chr5_+_102808057 0.31 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr13_-_98521998 0.31 ENST00000376547.7
serine/threonine kinase 24
chr16_+_20806630 0.30 ENST00000568647.5
RNA exonuclease 5
chr21_-_34511317 0.30 ENST00000611936.1
ENST00000337385.7
potassium voltage-gated channel subfamily E regulatory subunit 1
chr18_+_3449413 0.30 ENST00000549253.5
TGFB induced factor homeobox 1
chr1_+_36156096 0.30 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr11_+_47586678 0.29 ENST00000538490.3
family with sequence similarity 180 member B
chr9_+_132978651 0.29 ENST00000636137.1
growth factor independent 1B transcriptional repressor
chr2_+_227325349 0.29 ENST00000436237.5
ENST00000443428.6
ENST00000418961.5
mitochondrial fission factor
chr8_+_26383043 0.28 ENST00000380629.7
BCL2 interacting protein 3 like
chr6_-_30160880 0.28 ENST00000376704.3
tripartite motif containing 10
chr17_+_60677822 0.27 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr1_-_22143088 0.27 ENST00000290167.11
Wnt family member 4
chr11_-_842508 0.27 ENST00000322028.5
RNA polymerase II, I and III subunit L
chr16_+_20806517 0.26 ENST00000348433.10
ENST00000568501.5
ENST00000261377.11
ENST00000566276.5
RNA exonuclease 5
chr1_-_51325924 0.26 ENST00000532836.5
ENST00000422925.6
tetratricopeptide repeat domain 39A
chr1_+_168280872 0.26 ENST00000367821.8
T-box transcription factor 19
chr17_+_36103819 0.25 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr16_+_20806604 0.25 ENST00000565340.5
RNA exonuclease 5
chr22_+_38656627 0.25 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr17_+_7306975 0.24 ENST00000336452.11
eukaryotic translation initiation factor 5A
chr7_-_142258027 0.24 ENST00000552471.1
ENST00000547058.6
serine protease 58
chr1_-_31798648 0.24 ENST00000528579.1
SPOC domain containing 1
chr19_-_39335999 0.23 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr19_-_49896868 0.23 ENST00000593956.5
ENST00000391826.7
interleukin 4 induced 1
chr2_+_161231078 0.23 ENST00000439442.1
TRAF family member associated NFKB activator
chr19_-_45322867 0.23 ENST00000221476.4
creatine kinase, M-type
chr10_+_28533706 0.23 ENST00000442148.6
ENST00000448193.5
WW domain containing adaptor with coiled-coil
chr3_-_122793772 0.22 ENST00000306103.3
HSPB1 associated protein 1
chr2_+_231592858 0.22 ENST00000313965.4
testis expressed 44
chr3_+_178807293 0.22 ENST00000358316.7
ENST00000617329.1
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr22_+_21015027 0.22 ENST00000413302.6
ENST00000401443.5
purinergic receptor P2X 6
chr3_-_53347512 0.21 ENST00000559748.5
ENST00000294241.10
ENST00000610213.6
ENST00000560624.5
decapping mRNA 1A
chr6_-_30161200 0.21 ENST00000449742.7
tripartite motif containing 10
chr16_+_20806698 0.21 ENST00000564274.5
ENST00000563068.1
RNA exonuclease 5
chr17_+_8413124 0.21 ENST00000582812.5
nudE neurodevelopment protein 1 like 1
chr3_-_71306012 0.20 ENST00000649431.1
ENST00000610810.5
forkhead box P1
chr9_+_93263948 0.18 ENST00000448251.5
WNK lysine deficient protein kinase 2
chr2_+_232406836 0.18 ENST00000295453.8
alkaline phosphatase, germ cell
chrX_+_102307022 0.18 ENST00000604790.2
nuclear RNA export factor 2
chr5_-_16738341 0.18 ENST00000515803.5
myosin X
chr19_-_10116827 0.17 ENST00000593054.5
eukaryotic translation initiation factor 3 subunit G
chr9_-_127778659 0.17 ENST00000314830.13
SH2 domain containing 3C
chr1_-_145885826 0.17 ENST00000544626.2
ENST00000355594.9
ankyrin repeat domain 35
chrX_-_154547546 0.17 ENST00000440967.5
ENST00000369620.6
ENST00000393564.6
glucose-6-phosphate dehydrogenase
chr3_+_182793478 0.17 ENST00000493826.1
ENST00000323116.10
ATPase phospholipid transporting 11B (putative)
chr19_+_5455409 0.16 ENST00000222033.6
zinc and ring finger 4
chr1_-_54406385 0.16 ENST00000610401.5
single stranded DNA binding protein 3
chr17_-_5111836 0.16 ENST00000575898.5
zinc finger protein 232
chr20_-_58515382 0.16 ENST00000371149.8
APC down-regulated 1 like
chr7_+_142740206 0.16 ENST00000422143.2
T cell receptor beta variable 29-1
chr2_+_23927309 0.15 ENST00000404924.5
UBX domain protein 2A
chrX_+_40623423 0.15 ENST00000423387.4
mitochondrial pyruvate carrier 1 like
chr8_-_16567362 0.15 ENST00000518026.5
macrophage scavenger receptor 1
chr17_+_41689862 0.15 ENST00000586699.1
eukaryotic translation initiation factor 1
chr10_-_103452356 0.14 ENST00000260743.10
calcium homeostasis modulator family member 2
chr10_+_102743938 0.14 ENST00000448841.7
WW domain binding protein 1 like
chr15_+_63121818 0.14 ENST00000413507.3
lactamase beta
chr8_+_26383102 0.13 ENST00000523949.5
BCL2 interacting protein 3 like
chr7_+_69967464 0.13 ENST00000664521.1
activator of transcription and developmental regulator AUTS2

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS3_TGIF2LX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.6 3.8 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.3 2.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.2 GO:0070295 renal water absorption(GO:0070295)
0.2 0.9 GO:1903413 cellular response to bile acid(GO:1903413)
0.2 2.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.8 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 3.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.9 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 2.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.8 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 3.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 1.6 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.4 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.7 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.5 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.1 0.4 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 1.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 1.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.2 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.2 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050) positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 2.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 1.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 3.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.4 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.7 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 4.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.5 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740) pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 1.0 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0035853 chromosome passenger complex localization to spindle midzone(GO:0035853)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0090071 rhythmic synaptic transmission(GO:0060024) negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.2 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.7 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.4 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 2.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 0.7 GO:0070701 mucus layer(GO:0070701)
0.2 1.7 GO:0032010 phagolysosome(GO:0032010)
0.1 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 3.5 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.8 GO:0005882 intermediate filament(GO:0005882)
0.0 2.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.0 GO:0005903 brush border(GO:0005903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.6 2.4 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.4 3.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.9 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 1.2 GO:0015254 glycerol channel activity(GO:0015254)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 2.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.9 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 2.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 13.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0016594 glycine binding(GO:0016594)
0.0 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0048185 activin binding(GO:0048185)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 3.5 GO:0051117 ATPase binding(GO:0051117)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 3.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 3.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis