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Illumina Body Map 2 (GSE30611)

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Results for MSX1

Z-value: 1.15

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Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
MSX1
ENSG00000163132.8 msh homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX1hg38_v1_chr4_+_4859658_48596720.383.2e-02Click!

Activity profile of MSX1 motif

Sorted Z-values of MSX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_6588082 5.45 ENST00000379953.6
LY86
lymphocyte antigen 86
chr1_-_167518583 3.74 ENST00000392122.3
CD247
CD247 molecule
chr1_-_167518521 3.60 ENST00000362089.10
CD247
CD247 molecule
chr13_-_37598750 3.42 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
POSTN
periostin
chr2_-_157488829 3.26 ENST00000435117.1
ENST00000439355.5
CYTIP
cytohesin 1 interacting protein
chr12_+_9827472 3.19 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
KLRF1
killer cell lectin like receptor F1
chr1_-_160523204 3.01 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAMF6
SLAM family member 6
chr6_-_32816910 2.81 ENST00000447394.1
ENST00000438763.7
HLA-DOB
major histocompatibility complex, class II, DO beta
chr11_-_104968533 2.69 ENST00000444739.7
CASP4
caspase 4
chr1_+_110873135 2.60 ENST00000271324.6
CD53
CD53 molecule
chr2_-_218166951 2.55 ENST00000295683.3
CXCR1
C-X-C motif chemokine receptor 1
chr7_+_142560423 2.37 ENST00000620569.1
TRBV12-3
T cell receptor beta variable 12-3
chr8_+_24384275 2.18 ENST00000256412.8
ADAMDEC1
ADAM like decysin 1
chr1_+_159015665 2.13 ENST00000567661.5
ENST00000474473.1
IFI16
interferon gamma inducible protein 16
chr14_+_22163226 2.10 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5
chr12_+_55931148 2.07 ENST00000549629.5
ENST00000555218.5
ENST00000331886.10
DGKA
diacylglycerol kinase alpha
chr8_+_24384455 2.03 ENST00000522298.1
ADAMDEC1
ADAM like decysin 1
chr14_-_106791226 2.01 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr14_+_51860632 2.01 ENST00000555472.5
ENST00000556766.5
GNG2
G protein subunit gamma 2
chr5_+_83471668 2.00 ENST00000342785.8
ENST00000343200.9
VCAN
versican
chr3_-_21751189 2.00 ENST00000281523.8
ZNF385D
zinc finger protein 385D
chr19_-_7747511 1.98 ENST00000593660.5
ENST00000204801.12
ENST00000315591.12
ENST00000354397.10
ENST00000394161.9
ENST00000593821.5
ENST00000602261.5
ENST00000601256.1
ENST00000601951.5
ENST00000315599.12
CD209
CD209 molecule
chr3_-_123620496 1.98 ENST00000578202.1
MYLK
myosin light chain kinase
chr12_+_9827517 1.94 ENST00000537723.5
KLRF1
killer cell lectin like receptor F1
chr3_+_114294020 1.91 ENST00000383671.8
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr1_+_158845798 1.91 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr14_+_55129242 1.90 ENST00000254301.14
ENST00000554715.1
LGALS3
galectin 3
chr6_+_130018565 1.89 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr11_+_62270150 1.89 ENST00000525380.1
ENST00000227918.3
SCGB2A2
secretoglobin family 2A member 2
chr18_-_5396265 1.84 ENST00000579951.2
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr5_+_83471764 1.81 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
VCAN
versican
chr3_-_123620571 1.71 ENST00000583087.5
MYLK
myosin light chain kinase
chr1_+_224183197 1.68 ENST00000323699.9
DEGS1
delta 4-desaturase, sphingolipid 1
chr5_+_83471736 1.67 ENST00000265077.8
VCAN
versican
chrX_+_135520616 1.61 ENST00000370752.4
ENST00000639893.2
INTS6L
integrator complex subunit 6 like
chr6_+_96563117 1.56 ENST00000450218.6
FHL5
four and a half LIM domains 5
chr1_+_111229692 1.51 ENST00000466741.5
ENST00000477185.6
CHI3L2
chitinase 3 like 2
chr10_+_17228215 1.47 ENST00000544301.7
VIM
vimentin
chr19_-_7747559 1.40 ENST00000394173.8
CD209
CD209 molecule
chr1_-_150765785 1.37 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
CTSS
cathepsin S
chr2_-_144521042 1.27 ENST00000637267.2
ZEB2
zinc finger E-box binding homeobox 2
chr7_-_29990113 1.23 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
SCRN1
secernin 1
chr1_+_76074698 1.17 ENST00000328299.4
ST6GALNAC3
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr7_-_55552741 1.17 ENST00000418904.5
VOPP1
VOPP1 WW domain binding protein
chr19_-_53159004 1.14 ENST00000599096.1
ENST00000597183.5
ENST00000601804.5
ENST00000334197.12
ENST00000601469.2
ENST00000452676.6
ZNF347
zinc finger protein 347
chr4_+_118888829 1.13 ENST00000448416.6
ENST00000307142.9
ENST00000429713.7
SYNPO2
synaptopodin 2
chr8_-_98045532 1.12 ENST00000396070.6
ENST00000287038.8
ENST00000523172.5
RPL30
ribosomal protein L30
chr2_+_188991663 1.10 ENST00000450867.1
COL3A1
collagen type III alpha 1 chain
chr12_+_8913875 1.08 ENST00000538657.5
PHC1
polyhomeotic homolog 1
chrX_-_123623155 0.97 ENST00000618150.4
THOC2
THO complex 2
chr6_+_28281555 0.96 ENST00000259883.3
ENST00000682144.1
PGBD1
piggyBac transposable element derived 1
chr11_+_7485353 0.93 ENST00000530135.5
OLFML1
olfactomedin like 1
chrX_+_1591590 0.92 ENST00000313871.9
ENST00000381261.8
AKAP17A
A-kinase anchoring protein 17A
chr13_+_48976597 0.91 ENST00000541916.5
FNDC3A
fibronectin type III domain containing 3A
chr8_-_70245343 0.90 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr4_-_163613505 0.90 ENST00000339875.9
MARCHF1
membrane associated ring-CH-type finger 1
chr16_+_28974221 0.89 ENST00000567771.5
ENST00000568388.5
SPNS1
sphingolipid transporter 1 (putative)
chr17_-_39778213 0.88 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3
chr8_-_98045507 0.88 ENST00000521291.5
RPL30
ribosomal protein L30
chr17_-_50707855 0.86 ENST00000285243.7
ANKRD40
ankyrin repeat domain 40
chr21_+_42199686 0.85 ENST00000398457.6
ABCG1
ATP binding cassette subfamily G member 1
chr18_+_63970029 0.84 ENST00000353706.6
ENST00000542677.5
ENST00000397985.7
ENST00000636430.1
ENST00000397988.7
ENST00000448851.5
SERPINB8
serpin family B member 8
chr6_+_28124596 0.83 ENST00000340487.5
ZSCAN16
zinc finger and SCAN domain containing 16
chr19_-_4558417 0.81 ENST00000586965.1
SEMA6B
semaphorin 6B
chr1_-_244859297 0.81 ENST00000483966.3
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr9_+_76459152 0.81 ENST00000444201.6
ENST00000376730.5
GCNT1
glucosaminyl (N-acetyl) transferase 1
chr11_+_101914997 0.81 ENST00000263468.13
CEP126
centrosomal protein 126
chr10_-_32378720 0.78 ENST00000375110.6
EPC1
enhancer of polycomb homolog 1
chr21_+_29130630 0.78 ENST00000399926.5
ENST00000399928.6
MAP3K7CL
MAP3K7 C-terminal like
chr12_+_55931070 0.76 ENST00000555090.5
DGKA
diacylglycerol kinase alpha
chr21_+_32298849 0.75 ENST00000303645.10
MRAP
melanocortin 2 receptor accessory protein
chr6_-_32128191 0.75 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
ATF6B
activating transcription factor 6 beta
chr2_-_88627365 0.74 ENST00000303236.9
EIF2AK3
eukaryotic translation initiation factor 2 alpha kinase 3
chr1_-_72100930 0.74 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr7_-_20217342 0.74 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr15_-_77420135 0.72 ENST00000560626.6
PEAK1
pseudopodium enriched atypical kinase 1
chr3_+_171843337 0.72 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr19_-_53254688 0.69 ENST00000594517.5
ENST00000601413.5
ENST00000594681.5
ZNF677
zinc finger protein 677
chr15_-_77420087 0.69 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
PEAK1
pseudopodium enriched atypical kinase 1
chr11_-_93197932 0.67 ENST00000326402.9
SLC36A4
solute carrier family 36 member 4
chr11_-_114559866 0.67 ENST00000534921.2
NXPE1
neurexophilin and PC-esterase domain family member 1
chr17_-_8210203 0.67 ENST00000578549.5
ENST00000582368.5
AURKB
aurora kinase B
chrX_-_123622809 0.64 ENST00000441692.5
THOC2
THO complex 2
chr6_+_156776020 0.63 ENST00000346085.10
ARID1B
AT-rich interaction domain 1B
chr9_-_15510289 0.63 ENST00000397519.6
PSIP1
PC4 and SFRS1 interacting protein 1
chr21_+_32298945 0.62 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr13_-_52159559 0.60 ENST00000620675.4
ENST00000610828.5
NEK3
NIMA related kinase 3
chr16_-_29923237 0.60 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr19_-_53254841 0.58 ENST00000601828.5
ENST00000599012.5
ENST00000598513.6
ENST00000598806.5
ZNF677
zinc finger protein 677
chr15_+_76336755 0.57 ENST00000290759.9
ISL2
ISL LIM homeobox 2
chr8_-_25424260 0.56 ENST00000421054.7
GNRH1
gonadotropin releasing hormone 1
chr3_-_15440560 0.52 ENST00000595627.5
ENST00000597949.1
ENST00000494875.3
ENST00000595975.1
ENST00000598878.1
EAF1-AS1
METTL6
EAF1 antisense RNA 1
methyltransferase like 6
chr2_+_157257687 0.50 ENST00000259056.5
GALNT5
polypeptide N-acetylgalactosaminyltransferase 5
chrX_-_14873027 0.50 ENST00000452869.1
ENST00000398334.5
ENST00000650831.1
ENST00000324138.7
FANCB
FA complementation group B
chr1_-_149936324 0.49 ENST00000369140.7
MTMR11
myotubularin related protein 11
chr13_-_44474250 0.48 ENST00000472477.1
TSC22D1
TSC22 domain family member 1
chr11_-_114559847 0.46 ENST00000251921.6
NXPE1
neurexophilin and PC-esterase domain family member 1
chr2_-_206718396 0.46 ENST00000452335.2
DYTN
dystrotelin
chr12_-_12684490 0.45 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr11_+_124566660 0.45 ENST00000641670.1
OR8A1
olfactory receptor family 8 subfamily A member 1
chr12_+_14408482 0.44 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr4_+_145680146 0.42 ENST00000438731.7
C4orf51
chromosome 4 open reading frame 51
chr9_+_87497222 0.41 ENST00000358077.9
DAPK1
death associated protein kinase 1
chr15_+_51377247 0.41 ENST00000396399.6
GLDN
gliomedin
chr22_+_50738198 0.41 ENST00000216139.10
ENST00000529621.1
ACR
acrosin
chr14_+_55027576 0.39 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr13_-_52159844 0.39 ENST00000611833.4
NEK3
NIMA related kinase 3
chr17_+_76732978 0.38 ENST00000587459.1
ENSG00000267168.1
novel protein
chr12_+_104986292 0.35 ENST00000552951.7
ENST00000637147.1
ENST00000622317.5
ENST00000280749.5
C12orf45
chromosome 12 open reading frame 45
chr15_+_51377410 0.34 ENST00000612989.1
GLDN
gliomedin
chr1_+_206635521 0.34 ENST00000367109.8
DYRK3
dual specificity tyrosine phosphorylation regulated kinase 3
chr12_-_52517929 0.33 ENST00000548409.5
KRT5
keratin 5
chrX_-_11265975 0.32 ENST00000303025.10
ENST00000657361.1
ARHGAP6
Rho GTPase activating protein 6
chr2_+_95165784 0.29 ENST00000622059.4
ENST00000614034.5
ENST00000611147.1
ZNF2
zinc finger protein 2
chr14_-_63728027 0.28 ENST00000247225.7
SGPP1
sphingosine-1-phosphate phosphatase 1
chr17_-_31901658 0.27 ENST00000261708.9
UTP6
UTP6 small subunit processome component
chr17_+_32350132 0.27 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
ZNF207
zinc finger protein 207
chr4_+_70518583 0.26 ENST00000504451.1
AMTN
amelotin
chr9_-_123184233 0.24 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr20_+_54208072 0.24 ENST00000371419.7
PFDN4
prefoldin subunit 4
chr1_+_74235377 0.24 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr15_+_77420668 0.23 ENST00000381714.7
ENST00000558651.5
HMG20A
high mobility group 20A
chr11_+_55635113 0.22 ENST00000641760.1
OR4P4
olfactory receptor family 4 subfamily P member 4
chr6_-_109483208 0.22 ENST00000230122.4
ZBTB24
zinc finger and BTB domain containing 24
chr1_-_152115443 0.21 ENST00000614923.1
TCHH
trichohyalin
chr6_+_118548289 0.20 ENST00000357525.6
PLN
phospholamban
chr9_+_127264740 0.20 ENST00000373387.9
GARNL3
GTPase activating Rap/RanGAP domain like 3
chr10_+_27532521 0.19 ENST00000683924.1
RAB18
RAB18, member RAS oncogene family
chr11_+_6863057 0.18 ENST00000641461.1
OR10A2
olfactory receptor family 10 subfamily A member 2
chr14_+_30577752 0.18 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr6_+_135851681 0.18 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr14_+_55027200 0.17 ENST00000395472.2
ENST00000555846.2
SOCS4
suppressor of cytokine signaling 4
chr9_-_92482350 0.17 ENST00000375543.2
ASPN
asporin
chr1_-_53940100 0.16 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr4_+_118888918 0.16 ENST00000434046.6
SYNPO2
synaptopodin 2
chr7_+_139133744 0.14 ENST00000430935.5
ENST00000495038.5
ENST00000474035.6
ENST00000478836.6
ENST00000464848.5
ENST00000343187.8
TTC26
tetratricopeptide repeat domain 26
chr14_+_93185304 0.13 ENST00000415050.3
TMEM251
transmembrane protein 251
chr2_-_135530561 0.11 ENST00000536680.5
ENST00000401392.5
ZRANB3
zinc finger RANBP2-type containing 3
chr9_-_92482461 0.11 ENST00000651738.1
ASPN
asporin
chr9_-_83978429 0.11 ENST00000351839.7
HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr2_-_168890368 0.10 ENST00000282074.7
SPC25
SPC25 component of NDC80 kinetochore complex
chr4_-_106238690 0.10 ENST00000503516.1
TBCK
TBC1 domain containing kinase
chr3_-_94062906 0.09 ENST00000314636.3
ENST00000394221.3
DHFR2
dihydrofolate reductase 2
chr15_-_42208153 0.08 ENST00000348544.4
ENST00000318006.10
VPS39
VPS39 subunit of HOPS complex
chr18_-_72865680 0.08 ENST00000397929.5
NETO1
neuropilin and tolloid like 1
chrX_+_70282093 0.08 ENST00000509895.5
ENST00000374473.6
ENST00000276066.4
RAB41
RAB41, member RAS oncogene family
chr7_-_105691637 0.07 ENST00000472195.1
ATXN7L1
ataxin 7 like 1
chr9_-_23779369 0.07 ENST00000440102.1
ELAVL2
ELAV like RNA binding protein 2
chr15_+_51377315 0.05 ENST00000558426.5
GLDN
gliomedin
chr16_+_69311339 0.05 ENST00000254950.13
VPS4A
vacuolar protein sorting 4 homolog A
chr2_-_77522210 0.05 ENST00000409282.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr2_+_188292814 0.05 ENST00000409580.5
ENST00000409637.7
GULP1
GULP PTB domain containing engulfment adaptor 1
chr20_+_35542038 0.03 ENST00000357394.8
ENST00000348547.7
ENST00000416206.5
ENST00000640748.1
ENST00000411577.5
ENST00000413587.5
ERGIC3
ERGIC and golgi 3
chr7_+_141708353 0.03 ENST00000397541.6
WEE2
WEE2 oocyte meiosis inhibiting kinase
chr1_-_158426237 0.02 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr17_+_74935892 0.02 ENST00000328801.6
OTOP3
otopetrin 3
chr13_+_114179272 0.02 ENST00000646158.1
ENST00000636692.1
CFAP97D2
CFAP97 domain containing 2
chr8_+_28891304 0.02 ENST00000355231.9
HMBOX1
homeobox containing 1
chr6_+_138377905 0.00 ENST00000573100.2
SMIM28
small integral membrane protein 28
chr17_-_44363839 0.00 ENST00000293443.12
FAM171A2
family with sequence similarity 171 member A2
chr1_-_247536440 0.00 ENST00000366487.4
ENST00000641802.1
OR2C3
olfactory receptor family 2 subfamily C member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.8 3.4 GO:0046968 peptide antigen transport(GO:0046968)
0.7 3.4 GO:1990523 bone regeneration(GO:1990523)
0.5 5.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.5 4.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.0 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.5 1.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.4 2.5 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.4 1.9 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.3 0.8 GO:0009720 detection of hormone stimulus(GO:0009720)
0.3 2.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 0.9 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 0.6 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 5.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 3.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.6 GO:1990637 response to prolactin(GO:1990637)
0.1 6.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.5 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.8 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 1.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 2.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.6 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 2.6 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 1.0 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 1.9 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.9 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 0.7 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 2.0 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 2.1 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.0 1.2 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.8 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.9 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 1.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 2.4 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 1.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 1.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 1.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 1.4 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 4.5 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.4 2.7 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.2 1.4 GO:0036021 endolysosome lumen(GO:0036021)
0.1 2.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 4.5 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 5.5 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 3.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.4 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.5 1.4 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.4 2.5 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.4 3.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 5.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 2.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 3.4 GO:0046790 virion binding(GO:0046790)
0.2 0.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.9 GO:0019863 IgE binding(GO:0019863)
0.2 1.5 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.7 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 2.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.9 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 2.7 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0004040 amidase activity(GO:0004040)
0.1 2.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.5 GO:0004568 chitinase activity(GO:0004568)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 2.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 7.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.6 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 1.3 GO:0031005 filamin binding(GO:0031005)
0.0 1.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 2.0 GO:0002039 p53 binding(GO:0002039)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 7.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 5.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions