ISMARA results: MSX2

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Illumina Body Map 2 (GSE30611)

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Results for MSX2

Z-value: 0.79

Motif logo

Transcription factors associated with MSX2

Gene Symbol	Gene ID	Gene Info
MSX2 Ensembl NCBI GeneCards UniProt	ENSG00000120149.9	msh homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
MSX2	hg38_v1_chr5_+_174724549_174724607	0.17	3.5e-01	Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_2045037 Show fit	2.71	ENST00000262113.9	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr14_+_32329341 Show fit	2.49	ENST00000557354.5 ENST00000557102.1 ENST00000557272.1	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 6
chr8_+_2045058 Show fit	2.44	ENST00000523438.1	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr14_+_32329256 Show fit	2.30	ENST00000280979.9	AKAP6 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 6
chrX_-_21658324 Show fit	2.15	ENST00000379499.3	KLHL34 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 34
chr11_-_13495984 Show fit	2.13	ENST00000282091.6	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr19_+_50203607 Show fit	2.06	ENST00000642316.2 ENST00000425460.6 ENST00000440075.6 ENST00000376970.6 ENST00000599920.5	MYH14 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 14
chr11_-_13496018 Show fit	2.00	ENST00000529816.1	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr8_+_91249307 Show fit	1.88	ENST00000309536.6 ENST00000276609.8	SLC26A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 7
chrX_-_15314543 Show fit	1.53	ENST00000344384.8	ASB11 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 11
chr15_+_40953463 Show fit	1.27	ENST00000617768.5	CHAC1 Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr5_+_96662046 Show fit	1.25	ENST00000338252.7 ENST00000508830.5	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr19_-_45782479 Show fit	1.12	ENST00000447742.6 ENST00000354227.9 ENST00000291270.9 ENST00000683086.1 ENST00000343373.10	DMPK Ensembl NCBI GeneCards UniProt Show fit	DM1 protein kinase
chr5_+_96662366 Show fit	1.10	ENST00000675179.1 ENST00000421689.6 ENST00000674984.1 ENST00000512620.5	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr5_+_96662314 Show fit	1.03	ENST00000674702.1	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr4_-_145180496 Show fit	0.96	ENST00000447906.8	OTUD4 Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase 4
chr5_+_96662214 Show fit	0.95	ENST00000395812.6	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr7_-_100586119 Show fit	0.93	ENST00000310300.11	LRCH4 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeats and calponin homology domain containing 4
chr19_-_45782388 Show fit	0.90	ENST00000458663.6	DMPK Ensembl NCBI GeneCards UniProt Show fit	DM1 protein kinase
chr20_-_51802509 Show fit	0.84	ENST00000371539.7 ENST00000217086.9	SALL4 Ensembl NCBI GeneCards UniProt Show fit	spalt like transcription factor 4
chr5_+_96662181 Show fit	0.78	ENST00000511097.6	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr10_+_97446194 Show fit	0.78	ENST00000370846.8 ENST00000352634.8 ENST00000353979.7 ENST00000370842.6 ENST00000345745.9	ZDHHC16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 16
chr9_+_121567057 Show fit	0.68	ENST00000394340.7 ENST00000436835.5 ENST00000259371.6	DAB2IP Ensembl NCBI GeneCards UniProt Show fit	DAB2 interacting protein
chr7_-_88795732 Show fit	0.67	ENST00000297203.3	TEX47 Ensembl NCBI GeneCards UniProt Show fit	testis expressed 47
chr8_+_9555900 Show fit	0.67	ENST00000310430.11 ENST00000520408.5 ENST00000522110.1	TNKS Ensembl NCBI GeneCards UniProt Show fit	tankyrase
chr1_+_202348687 Show fit	0.64	ENST00000608999.6 ENST00000391959.5 ENST00000480184.5	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr19_-_45584769 Show fit	0.64	ENST00000263275.5	OPA3 Ensembl NCBI GeneCards UniProt Show fit	outer mitochondrial membrane lipid metabolism regulator OPA3
chr2_-_73233206 Show fit	0.62	ENST00000258083.3	PRADC1 Ensembl NCBI GeneCards UniProt Show fit	protease associated domain containing 1
chr3_-_120682113 Show fit	0.61	ENST00000476082.2	HGD Ensembl NCBI GeneCards UniProt Show fit	homogentisate 1,2-dioxygenase
chr15_+_40952962 Show fit	0.60	ENST00000444189.7	CHAC1 Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr10_+_97446137 Show fit	0.60	ENST00000370854.7 ENST00000393760.6 ENST00000414567.5	ZDHHC16 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 16
chr7_+_100586304 Show fit	0.60	ENST00000241071.11	FBXO24 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 24
chr9_+_34646627 Show fit	0.58	ENST00000556278.1	ENSG00000258728.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein (GALT-IL11RA readthrough)
chr1_+_158461574 Show fit	0.58	ENST00000641432.1 ENST00000641460.1 ENST00000641535.1 ENST00000641971.1	OR10K1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily K member 1
chr1_+_248508073 Show fit	0.57	ENST00000641804.1	OR2G6 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily G member 6
chr17_-_13017590 Show fit	0.57	ENST00000609757.5 ENST00000581499.6 ENST00000580504.5	ELAC2 Ensembl NCBI GeneCards UniProt Show fit	elaC ribonuclease Z 2
chr1_-_151790475 Show fit	0.57	ENST00000368825.7 ENST00000368823.5 ENST00000368824.8 ENST00000458431.6 ENST00000368827.10 ENST00000440583.6	TDRKH Ensembl NCBI GeneCards UniProt Show fit	tudor and KH domain containing
chr1_-_8817633 Show fit	0.56	ENST00000400908.7	RERE Ensembl NCBI GeneCards UniProt Show fit	arginine-glutamic acid dipeptide repeats
chr20_-_56392131 Show fit	0.56	ENST00000422322.5 ENST00000371356.6 ENST00000451915.1 ENST00000347343.6 ENST00000395911.5 ENST00000395915.8 ENST00000395907.5 ENST00000441357.5 ENST00000456249.5 ENST00000420474.5 ENST00000395914.5 ENST00000312783.10 ENST00000395913.7	AURKA Ensembl NCBI GeneCards UniProt Show fit	aurora kinase A
chr19_-_19138442 Show fit	0.56	ENST00000587583.6 ENST00000450333.6 ENST00000587096.5 ENST00000162044.14 ENST00000592369.1 ENST00000587915.1	TMEM161A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 161A
chrX_-_8801337 Show fit	0.52	ENST00000543214.1 ENST00000381003.7	FAM9A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 9 member A
chr17_+_12665882 Show fit	0.52	ENST00000425538.6	MYOCD Ensembl NCBI GeneCards UniProt Show fit	myocardin
chrX_-_140505058 Show fit	0.52	ENST00000370536.5	SOX3 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 3
chr1_+_202348727 Show fit	0.51	ENST00000356764.6	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr6_-_166627244 Show fit	0.49	ENST00000265678.9	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr7_+_99828010 Show fit	0.48	ENST00000631161.2 ENST00000354829.7 ENST00000342499.8 ENST00000417625.5 ENST00000415413.5 ENST00000444905.5 ENST00000222382.5 ENST00000312017.9	CYP3A43 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 3 subfamily A member 43
chr5_+_31532277 Show fit	0.48	ENST00000507818.6 ENST00000325366.14	C5orf22 Ensembl NCBI GeneCards UniProt Show fit	chromosome 5 open reading frame 22
chr3_-_115147237 Show fit	0.48	ENST00000357258.8	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr1_+_152970646 Show fit	0.47	ENST00000328051.3	SPRR4 Ensembl NCBI GeneCards UniProt Show fit	small proline rich protein 4
chr14_-_52069228 Show fit	0.47	ENST00000617139.4	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr7_+_131110087 Show fit	0.47	ENST00000421797.6	MKLN1 Ensembl NCBI GeneCards UniProt Show fit	muskelin 1
chr5_-_31532039 Show fit	0.47	ENST00000511367.6 ENST00000344624.8 ENST00000513349.5	DROSHA Ensembl NCBI GeneCards UniProt Show fit	drosha ribonuclease III
chr14_-_23035223 Show fit	0.45	ENST00000425762.2	PSMB5 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 5
chr19_+_50329637 Show fit	0.45	ENST00000600355.5	NR1H2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group H member 2
chr1_+_151762899 Show fit	0.44	ENST00000635322.1 ENST00000321531.10	OAZ3 Ensembl NCBI GeneCards UniProt Show fit	ornithine decarboxylase antizyme 3
chr20_-_51802433 Show fit	0.44	ENST00000395997.3	SALL4 Ensembl NCBI GeneCards UniProt Show fit	spalt like transcription factor 4
chr3_-_120682215 Show fit	0.43	ENST00000283871.10	HGD Ensembl NCBI GeneCards UniProt Show fit	homogentisate 1,2-dioxygenase
chr16_+_69311339 Show fit	0.43	ENST00000254950.13	VPS4A Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 4 homolog A
chrX_+_77899440 Show fit	0.43	ENST00000373335.4 ENST00000475465.1 ENST00000650309.2 ENST00000647835.1	COX7B Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 7B
chr14_-_52069039 Show fit	0.42	ENST00000216286.10	NID2 Ensembl NCBI GeneCards UniProt Show fit	nidogen 2
chr1_-_21050952 Show fit	0.41	ENST00000264211.12	EIF4G3 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 3
chr3_-_115147277 Show fit	0.40	ENST00000675478.1	ZBTB20 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 20
chr4_+_70195719 Show fit	0.39	ENST00000683306.1	ODAM Ensembl NCBI GeneCards UniProt Show fit	odontogenic, ameloblast associated
chr12_+_52301833 Show fit	0.38	ENST00000293525.5	KRT86 Ensembl NCBI GeneCards UniProt Show fit	keratin 86
chr5_+_141177790 Show fit	0.38	ENST00000239444.4 ENST00000623995.1	PCDHB8 Ensembl NCBI GeneCards UniProt Show fit ENSG00000279472.1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 8 novel transcript
chr19_+_15082211 Show fit	0.38	ENST00000641398.1	OR1I1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 1 subfamily I member 1
chr1_-_23368301 Show fit	0.37	ENST00000374608.3	ZNF436 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 436
chr8_-_12755457 Show fit	0.36	ENST00000398246.8	LONRF1 Ensembl NCBI GeneCards UniProt Show fit	LON peptidase N-terminal domain and ring finger 1
chr19_-_45584810 Show fit	0.36	ENST00000323060.3	OPA3 Ensembl NCBI GeneCards UniProt Show fit	outer mitochondrial membrane lipid metabolism regulator OPA3
chr18_+_36129444 Show fit	0.35	ENST00000543127.5	ELP2 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 2
chr12_-_10802627 Show fit	0.35	ENST00000240687.2	TAS2R7 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 7
chr5_+_163437569 Show fit	0.35	ENST00000512163.5 ENST00000393929.5 ENST00000510097.5 ENST00000340828.7 ENST00000511490.4 ENST00000510664.5	CCNG1 Ensembl NCBI GeneCards UniProt Show fit	cyclin G1
chr21_-_18403754 Show fit	0.35	ENST00000284885.8	TMPRSS15 Ensembl NCBI GeneCards UniProt Show fit	transmembrane serine protease 15
chr7_-_100119317 Show fit	0.34	ENST00000440225.5	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr6_-_111605859 Show fit	0.34	ENST00000651359.1 ENST00000650859.1 ENST00000359831.8 ENST00000368761.11	TRAF3IP2 Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 2
chr19_+_45733429 Show fit	0.33	ENST00000457052.3	MEIOSIN Ensembl NCBI GeneCards UniProt Show fit	meiosis initiator
chr12_+_64405046 Show fit	0.33	ENST00000540203.5	XPOT Ensembl NCBI GeneCards UniProt Show fit	exportin for tRNA
chr7_-_100119840 Show fit	0.33	ENST00000437822.6	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr10_-_97445850 Show fit	0.32	ENST00000477692.6 ENST00000485122.6 ENST00000370886.9 ENST00000370885.8 ENST00000370902.8 ENST00000370884.5	EXOSC1 Ensembl NCBI GeneCards UniProt Show fit	exosome component 1
chr5_-_31532131 Show fit	0.32	ENST00000507438.5	DROSHA Ensembl NCBI GeneCards UniProt Show fit	drosha ribonuclease III
chrX_+_54920796 Show fit	0.32	ENST00000442098.5 ENST00000430420.5 ENST00000453081.5 ENST00000319167.12 ENST00000622017.4 ENST00000375022.8 ENST00000399736.5 ENST00000440072.5 ENST00000173898.12 ENST00000431115.5 ENST00000440759.5 ENST00000375041.6	TRO Ensembl NCBI GeneCards UniProt Show fit	trophinin
chr3_+_140678041 Show fit	0.31	ENST00000286349.4	TRIM42 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 42
chr20_+_56392353 Show fit	0.31	ENST00000415828.5 ENST00000428552.1	CSTF1 Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor subunit 1
chr14_-_21159060 Show fit	0.30	ENST00000641039.1 ENST00000641697.1	OR5AU1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily AU member 1
chr11_-_59426412 Show fit	0.29	ENST00000641361.1 ENST00000641673.1 ENST00000302040.6	OR5A2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily A member 2
chr8_-_42768602 Show fit	0.29	ENST00000534622.5	CHRNA6 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor nicotinic alpha 6 subunit
chr17_-_44968263 Show fit	0.29	ENST00000253407.4	C1QL1 Ensembl NCBI GeneCards UniProt Show fit	complement C1q like 1
chr7_-_100119323 Show fit	0.28	ENST00000523306.5 ENST00000344095.8 ENST00000417349.5 ENST00000493322.5 ENST00000520135.5 ENST00000460673.2 ENST00000453269.7 ENST00000452041.5 ENST00000452438.6 ENST00000451699.5	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr1_-_93585071 Show fit	0.28	ENST00000539242.5	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	BCAR3 adaptor protein, NSP family member
chr7_+_91940851 Show fit	0.27	ENST00000679821.1 ENST00000681722.1 ENST00000680181.1 ENST00000356239.8 ENST00000679521.1 ENST00000680952.1 ENST00000681412.1 ENST00000680766.1	AKAP9 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 9
chr20_+_33217325 Show fit	0.27	ENST00000375452.3 ENST00000375454.8	BPIFA3 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family A member 3
chr16_+_53099100 Show fit	0.27	ENST00000565832.5	CHD9 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 9
chr19_-_55464741 Show fit	0.27	ENST00000635964.2	C19orf85 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 85
chr12_+_28257195 Show fit	0.27	ENST00000381259.5	CCDC91 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 91
chr7_+_131110119 Show fit	0.27	ENST00000416992.6	MKLN1 Ensembl NCBI GeneCards UniProt Show fit	muskelin 1
chr12_-_53336342 Show fit	0.26	ENST00000537210.2 ENST00000536324.4	SP7 Ensembl NCBI GeneCards UniProt Show fit	Sp7 transcription factor
chrX_+_89921903 Show fit	0.26	ENST00000283891.6 ENST00000561129.2	TGIF2LX Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 2 like X-linked
chr3_-_180679468 Show fit	0.26	ENST00000651046.1 ENST00000476379.6	CCDC39 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 39
chr12_-_95003666 Show fit	0.25	ENST00000327772.7 ENST00000547157.1 ENST00000684171.1 ENST00000547986.5	NDUFA12 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit A12
chr10_-_103351074 Show fit	0.25	ENST00000337211.8	PCGF6 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 6
chr12_-_56645955 Show fit	0.25	ENST00000552959.5 ENST00000551020.5 ENST00000553007.2 ENST00000262030.8	ATP5F1B Ensembl NCBI GeneCards UniProt Show fit	ATP synthase F1 subunit beta
chr11_-_7941708 Show fit	0.25	ENST00000642047.1	OR10A3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 10 subfamily A member 3
chr11_+_57667974 Show fit	0.25	ENST00000528177.5 ENST00000287169.8	ZDHHC5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 5
chr8_-_116874386 Show fit	0.24	ENST00000520992.5	RAD21 Ensembl NCBI GeneCards UniProt Show fit	RAD21 cohesin complex component
chr12_+_107318395 Show fit	0.24	ENST00000420571.6 ENST00000280758.10	BTBD11 Ensembl NCBI GeneCards UniProt Show fit	BTB domain containing 11
chr11_-_122116215 Show fit	0.24	ENST00000560104.2	BLID Ensembl NCBI GeneCards UniProt Show fit	BH3-like motif containing, cell death inducer
chr9_-_5339874 Show fit	0.24	ENST00000223862.2	RLN1 Ensembl NCBI GeneCards UniProt Show fit	relaxin 1
chr1_+_244352627 Show fit	0.23	ENST00000366537.5 ENST00000308105.5	C1orf100 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 100
chr14_-_50561119 Show fit	0.23	ENST00000555216.5	MAP4K5 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 5
chr20_-_52105644 Show fit	0.23	ENST00000371523.8	ZFP64 Ensembl NCBI GeneCards UniProt Show fit	ZFP64 zinc finger protein
chr12_+_55549602 Show fit	0.23	ENST00000641569.1 ENST00000641851.1	OR6C4 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 6 subfamily C member 4
chr10_-_15719885 Show fit	0.21	ENST00000378076.4	ITGA8 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 8
chr3_-_165078480 Show fit	0.21	ENST00000264382.8	SI Ensembl NCBI GeneCards UniProt Show fit	sucrase-isomaltase
chr17_-_10469558 Show fit	0.21	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr9_+_34646589 Show fit	0.21	ENST00000450095.6	GALT Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase
chr17_-_31901658 Show fit	0.21	ENST00000261708.9	UTP6 Ensembl NCBI GeneCards UniProt Show fit	UTP6 small subunit processome component
chr9_+_34646654 Show fit	0.20	ENST00000378842.8	GALT Ensembl NCBI GeneCards UniProt Show fit	galactose-1-phosphate uridylyltransferase
chr10_-_103351133 Show fit	0.20	ENST00000369847.4	PCGF6 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 6
chr1_+_160400543 Show fit	0.20	ENST00000368061.3	VANGL2 Ensembl NCBI GeneCards UniProt Show fit	VANGL planar cell polarity protein 2
chr6_+_49499965 Show fit	0.20	ENST00000545705.1	GLYATL3 Ensembl NCBI GeneCards UniProt Show fit	glycine-N-acyltransferase like 3
chr10_-_45672708 Show fit	0.20	ENST00000374366.7 ENST00000374371.6 ENST00000344646.10	ZFAND4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 4
chr11_+_17276795 Show fit	0.20	ENST00000530964.5	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chrX_+_115593570 Show fit	0.20	ENST00000539310.5	PLS3 Ensembl NCBI GeneCards UniProt Show fit	plastin 3
chr11_+_57667747 Show fit	0.19	ENST00000527985.5	ZDHHC5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger DHHC-type palmitoyltransferase 5
chr1_-_228425350 Show fit	0.19	ENST00000366696.2	H3-4 Ensembl NCBI GeneCards UniProt Show fit	H3.4 histone
chr19_+_17267469 Show fit	0.18	ENST00000596335.5 ENST00000601436.5 ENST00000595632.5	BABAM1 Ensembl NCBI GeneCards UniProt Show fit	BRISC and BRCA1 A complex member 1
chr11_-_72112669 Show fit	0.18	ENST00000545944.5 ENST00000502597.2	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr6_-_116545658 Show fit	0.18	ENST00000368602.4	TRAPPC3L Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 3 like
chr1_-_197146620 Show fit	0.17	ENST00000367409.9 ENST00000680265.1	ASPM Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr1_-_153922742 Show fit	0.17	ENST00000634408.1 ENST00000634791.1	GATAD2B Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2B
chr11_+_55723776 Show fit	0.16	ENST00000641440.1	OR5D3P Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily D member 3 pseudogene
chr7_+_48171451 Show fit	0.15	ENST00000435803.6	ABCA13 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 13
chr4_-_106368772 Show fit	0.14	ENST00000638719.4	GIMD1 Ensembl NCBI GeneCards UniProt Show fit	GIMAP family P-loop NTPase domain containing 1
chr1_-_153922901 Show fit	0.14	ENST00000634401.1 ENST00000368655.5	GATAD2B Ensembl NCBI GeneCards UniProt Show fit	GATA zinc finger domain containing 2B
chr1_-_197146688 Show fit	0.13	ENST00000294732.11	ASPM Ensembl NCBI GeneCards UniProt Show fit	assembly factor for spindle microtubules
chr7_+_91940836 Show fit	0.13	ENST00000680534.1 ENST00000680513.1 ENST00000680072.1	AKAP9 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 9
chr4_-_137532452 Show fit	0.12	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr7_-_100119291 Show fit	0.12	ENST00000431404.2	TAF6 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 6
chr11_+_124566660 Show fit	0.12	ENST00000641670.1	OR8A1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 8 subfamily A member 1
chrX_-_70049938 Show fit	0.12	ENST00000276101.7	AWAT2 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA wax alcohol acyltransferase 2
chr19_+_17267376 Show fit	0.12	ENST00000447614.6 ENST00000359435.8 ENST00000599474.5 ENST00000599057.5 ENST00000598188.6 ENST00000601043.5	BABAM1 Ensembl NCBI GeneCards UniProt Show fit	BRISC and BRCA1 A complex member 1
chr11_-_58440173 Show fit	0.11	ENST00000302572.2	OR5B12 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily B member 12
chr6_+_132538290 Show fit	0.11	ENST00000434551.2	TAAR9 Ensembl NCBI GeneCards UniProt Show fit	trace amine associated receptor 9
chr4_-_108762964 Show fit	0.11	ENST00000512646.5 ENST00000411864.6 ENST00000296486.8 ENST00000510706.5	ETNPPL Ensembl NCBI GeneCards UniProt Show fit	ethanolamine-phosphate phospho-lyase
chr19_+_42313374 Show fit	0.10	ENST00000598766.1 ENST00000673187.1	TMEM145 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 145
chr13_+_48037692 Show fit	0.10	ENST00000258662.3	NUDT15 Ensembl NCBI GeneCards UniProt Show fit	nudix hydrolase 15
chr3_-_48635426 Show fit	0.10	ENST00000455886.6 ENST00000431739.5 ENST00000426599.1 ENST00000383733.7 ENST00000395550.7 ENST00000420764.6 ENST00000337000.12	SLC26A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 6
chr20_+_56392607 Show fit	0.09	ENST00000217109.9 ENST00000452950.1	CSTF1 Ensembl NCBI GeneCards UniProt Show fit	cleavage stimulation factor subunit 1
chr16_+_69424634 Show fit	0.09	ENST00000515314.6 ENST00000561792.6 ENST00000568237.1	CYB5B Ensembl NCBI GeneCards UniProt Show fit	cytochrome b5 type B
chr12_-_119877300 Show fit	0.09	ENST00000392521.7	CIT Ensembl NCBI GeneCards UniProt Show fit	citron rho-interacting serine/threonine kinase
chr16_-_46621345 Show fit	0.08	ENST00000303383.8	SHCBP1 Ensembl NCBI GeneCards UniProt Show fit	SHC binding and spindle associated 1
chr1_+_174700413 Show fit	0.08	ENST00000529145.6 ENST00000325589.9	RABGAP1L Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1 like
chr21_-_30881572 Show fit	0.08	ENST00000332378.6	KRTAP11-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 11-1
chr9_-_104536856 Show fit	0.08	ENST00000641090.1	OR13C3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 13 subfamily C member 3
chr15_-_37101205 Show fit	0.07	ENST00000338564.9 ENST00000558313.5 ENST00000340545.9	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr1_-_248562772 Show fit	0.07	ENST00000641069.1	OR2T29 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily T member 29
chr1_+_15236509 Show fit	0.07	ENST00000683790.1	FHAD1 Ensembl NCBI GeneCards UniProt Show fit	forkhead associated phosphopeptide binding domain 1
chr8_+_38974212 Show fit	0.07	ENST00000302495.5	HTRA4 Ensembl NCBI GeneCards UniProt Show fit	HtrA serine peptidase 4
chr4_+_70721953 Show fit	0.07	ENST00000381006.8 ENST00000226328.8	RUFY3 Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 3
chr11_-_124320197 Show fit	0.07	ENST00000624618.2	OR8D2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 8 subfamily D member 2
chr12_-_119877270 Show fit	0.06	ENST00000261833.11 ENST00000612548.4	CIT Ensembl NCBI GeneCards UniProt Show fit	citron rho-interacting serine/threonine kinase
chr6_+_25652272 Show fit	0.06	ENST00000334979.6	SCGN Ensembl NCBI GeneCards UniProt Show fit	secretagogin, EF-hand calcium binding protein
chr4_-_87528619 Show fit	0.06	ENST00000535835.5	SPARCL1 Ensembl NCBI GeneCards UniProt Show fit	SPARC like 1
chr12_+_53268326 Show fit	0.05	ENST00000553219.6	ESPL1 Ensembl NCBI GeneCards UniProt Show fit	extra spindle pole bodies like 1, separase
chr19_+_11374658 Show fit	0.05	ENST00000674460.1 ENST00000312423.4	SWSAP1 Ensembl NCBI GeneCards UniProt Show fit	SWIM-type zinc finger 7 associated protein 1
chr3_-_11643871 Show fit	0.05	ENST00000430365.7	VGLL4 Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 4
chr18_+_41955186 Show fit	0.05	ENST00000639914.1 ENST00000262039.9 ENST00000398870.7 ENST00000586545.5 ENST00000585528.5	PIK3C3 Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol 3-kinase catalytic subunit type 3
chr11_-_72112068 Show fit	0.04	ENST00000537644.5 ENST00000538919.5 ENST00000539395.1 ENST00000542531.5	ANAPC15 Ensembl NCBI GeneCards UniProt Show fit	anaphase promoting complex subunit 15
chr14_+_39267377 Show fit	0.04	ENST00000556148.5 ENST00000348007.7	MIA2 Ensembl NCBI GeneCards UniProt Show fit	MIA SH3 domain ER export factor 2
chr19_-_46634685 Show fit	0.03	ENST00000300873.4	GNG8 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 8
chr1_-_151459198 Show fit	0.03	ENST00000531094.5	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chr3_-_120285215 Show fit	0.02	ENST00000464295.6	GPR156 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 156
chr5_+_141417641 Show fit	0.02	ENST00000612073.1	PCDHGB7 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 7
chr6_-_111606260 Show fit	0.02	ENST00000340026.10	TRAF3IP2 Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 2
chr3_-_142029108 Show fit	0.02	ENST00000497579.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr11_+_17276989 Show fit	0.02	ENST00000533926.5	NUCB2 Ensembl NCBI GeneCards UniProt Show fit	nucleobindin 2
chr21_-_30598902 Show fit	0.01	ENST00000334897.4	KRTAP6-2 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 6-2
chr10_-_54801179 Show fit	0.01	ENST00000373955.5	PCDH15 Ensembl NCBI GeneCards UniProt Show fit	protocadherin related 15
chr17_-_40799939 Show fit	0.01	ENST00000306658.8	KRT28 Ensembl NCBI GeneCards UniProt Show fit	keratin 28
chr7_+_142554828 Show fit	0.01	ENST00000611787.1	TRBV11-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 11-3
chr1_+_43650118 Show fit	0.00	ENST00000372396.4	KDM4A Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 4A

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	4.1	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.6	5.1	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.5	4.8	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2	0.7	GO:0034183	negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.2	0.6	GO:0072684	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.2	5.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	0.6	GO:0007057	spindle assembly involved in female meiosis I(GO:0007057)
0.1	0.4	GO:0090108	positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1	0.4	GO:0015847	putrescine transport(GO:0015847)
0.1	0.4	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1	0.4	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499)
0.1	2.0	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	2.0	GO:0019532	oxalate transport(GO:0019532)
0.1	1.0	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.6	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.1	1.9	GO:0006751	glutathione catabolic process(GO:0006751)
0.1	0.7	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1	0.3	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.4	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	3.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.1	1.3	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.2	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.8	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.3	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.9	GO:0045199	maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.4	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.4	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.3	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.6	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	1.0	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.2	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.9	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.3	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.5	GO:0007530	sex determination(GO:0007530)
0.0	0.4	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0	0.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.4	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.9	GO:0045739	positive regulation of DNA repair(GO:0045739)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.1	GO:0097513	myosin II filament(GO:0097513)
0.3	0.8	GO:1903095	microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.3	4.8	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2	5.4	GO:0032982	myosin filament(GO:0032982)
0.2	0.6	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	1.0	GO:0044301	climbing fiber(GO:0044301)
0.1	0.4	GO:0044307	dendritic branch(GO:0044307)
0.1	0.6	GO:0071547	piP-body(GO:0071547)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.1	2.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.3	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.5	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.0	0.4	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.2	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0000798	nuclear cohesin complex(GO:0000798)
0.0	0.3	GO:0070552	BRISC complex(GO:0070552)
0.0	0.5	GO:0000800	lateral element(GO:0000800)
0.0	0.7	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.4	GO:0000815	ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0	0.3	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.5	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.4	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	1.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.4	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0097196	Shu complex(GO:0097196)
0.0	0.1	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0	1.1	GO:0031672	A band(GO:0031672)
0.0	1.3	GO:0000792	heterochromatin(GO:0000792)
0.0	0.2	GO:0030008	TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.1	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4	1.9	GO:0003839	gamma-glutamylcyclotransferase activity(GO:0003839)
0.3	1.0	GO:0004411	homogentisate 1,2-dioxygenase activity(GO:0004411)
0.2	4.8	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	5.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	0.4	GO:0001133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1	0.4	GO:0015203	polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1	4.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	2.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.6	GO:0042781	3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1	0.6	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.1	0.8	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.7	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.1	2.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.2	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.1	0.6	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.4	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0035539	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0	0.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.3	GO:0033038	bitter taste receptor activity(GO:0033038)
0.0	0.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.4	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.4	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.4	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	2.0	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.8	GO:0005549	odorant binding(GO:0005549)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
2.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
4.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
1.1	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.9	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)

Results for MSX2

Z-value: 0.79

Motif logo

Transcription factors associated with MSX2

Activity-expression correlation:

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: