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Illumina Body Map 2 (GSE30611)

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Results for MYOD1

Z-value: 3.35

Motif logo

Transcription factors associated with MYOD1

Gene Symbol Gene ID Gene Info
ENSG00000129152.4 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYOD1hg38_v1_chr11_+_17719564_177195770.921.0e-13Click!

Activity profile of MYOD1 motif

Sorted Z-values of MYOD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_45322867 25.96 ENST00000221476.4
creatine kinase, M-type
chr17_+_35147807 20.79 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr3_+_42685535 20.15 ENST00000287777.5
kelch like family member 40
chr4_-_176269213 19.65 ENST00000296525.7
ankyrin repeat and SOCS box containing 5
chr20_+_31819348 18.34 ENST00000375985.5
myosin light chain kinase 2
chr20_+_31819302 18.32 ENST00000375994.6
myosin light chain kinase 2
chr11_+_1838970 18.30 ENST00000381911.6
troponin I2, fast skeletal type
chr8_-_41665261 16.75 ENST00000522231.5
ENST00000314214.12
ENST00000348036.8
ENST00000522543.5
ankyrin 1
chr2_-_174764436 16.65 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr16_+_30375820 16.38 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr16_+_30372291 15.89 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_151734467 15.88 ENST00000397345.8
ENST00000427231.7
ENST00000409198.5
nebulin
chr2_+_169509693 15.24 ENST00000284669.2
kelch like family member 41
chr16_+_30374794 14.96 ENST00000322861.12
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_174764407 14.31 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr11_+_1839602 14.14 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr22_-_35622521 13.79 ENST00000419229.1
ENST00000406324.5
myoglobin
chr3_-_39192584 13.64 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr1_-_24112125 13.57 ENST00000374434.4
myomesin 3
chr9_-_35685462 13.07 ENST00000607559.1
tropomyosin 2
chr22_-_35617321 12.89 ENST00000397326.7
ENST00000442617.1
myoglobin
chr8_-_74321532 12.07 ENST00000342232.5
junctophilin 1
chr11_+_1839452 12.03 ENST00000381906.5
troponin I2, fast skeletal type
chr6_+_41053194 12.01 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr3_-_52452828 11.82 ENST00000496590.1
troponin C1, slow skeletal and cardiac type
chr6_+_17281341 11.60 ENST00000379052.10
RNA binding motif protein 24
chr17_-_81835042 11.53 ENST00000330261.5
ENST00000570394.1
protein phosphatase 1 regulatory subunit 27
chr19_+_50432885 11.40 ENST00000357701.6
myosin binding protein C2
chr3_-_155293665 10.91 ENST00000489090.2
small transmembrane regulator of ion transport 1
chr17_+_67044530 10.89 ENST00000226021.5
calcium voltage-gated channel auxiliary subunit gamma 1
chr8_-_41665200 10.75 ENST00000335651.6
ankyrin 1
chr15_-_42457513 10.22 ENST00000565611.5
ENST00000263805.8
zinc finger protein 106
chr15_-_42457556 9.96 ENST00000565948.1
zinc finger protein 106
chr19_-_49155130 9.79 ENST00000595625.1
histidine rich calcium binding protein
chr20_-_45827297 9.65 ENST00000372555.8
troponin C2, fast skeletal type
chr9_-_35689913 9.65 ENST00000329305.6
ENST00000645482.3
ENST00000647435.1
ENST00000378292.9
tropomyosin 2
chr2_+_219418369 9.47 ENST00000373960.4
desmin
chr19_-_49155384 9.44 ENST00000252825.9
histidine rich calcium binding protein
chr2_+_88067818 9.35 ENST00000444564.2
ENST00000419482.7
SET and MYND domain containing 1
chr14_-_64879900 9.22 ENST00000644917.1
ENST00000389720.4
spectrin beta, erythrocytic
chr15_-_34795541 9.22 ENST00000290378.6
actin alpha cardiac muscle 1
chr19_-_2256406 9.13 ENST00000300961.10
junctional sarcoplasmic reticulum protein 1
chr3_-_69122588 8.99 ENST00000420581.7
ENST00000489031.5
leiomodin 3
chr12_-_57251169 8.94 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr12_-_69699285 8.86 ENST00000553096.5
ENST00000330891.10
bestrophin 3
chr11_-_119381629 8.69 ENST00000260187.7
ENST00000455332.6
ubiquitin specific peptidase 2
chr5_+_150660841 8.57 ENST00000297130.4
myozenin 3
chr6_+_150143018 8.52 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr1_-_201112420 8.45 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr2_-_178807415 8.42 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
titin
chr11_-_47449129 8.42 ENST00000298854.7
ENST00000524487.5
ENST00000529341.1
ENST00000352508.7
receptor associated protein of the synapse
chr2_+_232526153 8.26 ENST00000449596.5
ENST00000258385.8
ENST00000543200.5
cholinergic receptor nicotinic delta subunit
chr5_+_150661243 8.08 ENST00000517768.6
myozenin 3
chr9_-_35684766 7.75 ENST00000644325.1
tropomyosin 2
chr19_+_53991630 7.65 ENST00000252729.7
calcium voltage-gated channel auxiliary subunit gamma 6
chr17_-_29622893 7.29 ENST00000345068.9
ENST00000584602.1
ENST00000388767.8
ENST00000580212.6
coronin 6
chr8_-_123541197 7.22 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr10_-_73651013 7.08 ENST00000372873.8
synaptopodin 2 like
chr1_-_201112451 7.08 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr4_+_151409169 7.03 ENST00000435205.6
family with sequence similarity 160 member A1
chr19_+_3933059 6.63 ENST00000616156.4
ENST00000168977.6
ENST00000599576.5
nicotinamide riboside kinase 2
chr1_+_77888490 6.50 ENST00000401035.7
ENST00000330010.12
nexilin F-actin binding protein
chr2_+_88067849 6.45 ENST00000438570.1
SET and MYND domain containing 1
chr8_-_143430727 6.36 ENST00000333480.3
MAF bZIP transcription factor A
chr19_+_16661121 6.33 ENST00000187762.7
ENST00000599479.1
transmembrane protein 38A
chr11_-_111912871 6.28 ENST00000528628.5
crystallin alpha B
chr14_-_64823148 6.23 ENST00000389722.7
spectrin beta, erythrocytic
chr17_+_48054675 6.22 ENST00000582155.5
ENST00000583378.5
ENST00000536222.5
nuclear factor, erythroid 2 like 1
chr15_-_40340900 6.15 ENST00000559313.5
coiled-coil domain containing 9B
chr2_-_218831791 6.11 ENST00000439262.6
ENST00000430489.1
protein kinase AMP-activated non-catalytic subunit gamma 3
chr17_-_29622732 6.11 ENST00000683819.1
ENST00000492276.7
coronin 6
chr4_-_185535498 5.86 ENST00000284767.12
ENST00000284771.7
ENST00000284770.10
ENST00000620787.5
ENST00000629667.2
PDZ and LIM domain 3
chr17_+_48054550 5.73 ENST00000584634.5
ENST00000580050.1
nuclear factor, erythroid 2 like 1
chr1_+_77888645 5.72 ENST00000440324.5
nexilin F-actin binding protein
chr3_+_35679690 5.68 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21
chr1_+_45913583 5.60 ENST00000372008.6
microtubule associated serine/threonine kinase 2
chr6_-_46015607 5.57 ENST00000644878.1
ENST00000644324.1
ENST00000672327.1
chloride intracellular channel 5
chr6_+_133241318 5.41 ENST00000430974.6
ENST00000355286.12
ENST00000355167.8
ENST00000431403.3
EYA transcriptional coactivator and phosphatase 4
chr1_-_114695533 5.41 ENST00000520113.7
adenosine monophosphate deaminase 1
chr21_+_29130961 5.39 ENST00000399925.5
MAP3K7 C-terminal like
chr21_+_29130630 5.36 ENST00000399926.5
ENST00000399928.6
MAP3K7 C-terminal like
chr10_+_103493931 5.35 ENST00000369780.8
neuralized E3 ubiquitin protein ligase 1
chr2_-_178794944 5.32 ENST00000436599.1
titin
chr17_-_29140373 5.30 ENST00000533420.3
myosin XVIIIA
chr1_-_114695613 5.22 ENST00000369538.4
adenosine monophosphate deaminase 1
chr1_+_77888612 5.11 ENST00000334785.12
nexilin F-actin binding protein
chr1_-_32702736 5.05 ENST00000373484.4
ENST00000409190.8
syncoilin, intermediate filament protein
chr17_+_48054481 5.05 ENST00000577411.5
nuclear factor, erythroid 2 like 1
chr1_+_56645299 4.99 ENST00000371244.9
ENST00000610361.1
protein kinase AMP-activated catalytic subunit alpha 2
chr8_-_33597750 4.99 ENST00000522982.1
dual specificity phosphatase 26
chr2_+_173090598 4.97 ENST00000422149.1
mitogen-activated protein kinase kinase kinase 20
chr1_+_45913647 4.95 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chrX_-_107775740 4.94 ENST00000372383.9
TSC22 domain family member 3
chr12_-_69699455 4.93 ENST00000266661.8
bestrophin 3
chr12_-_69699331 4.89 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr12_-_69699353 4.82 ENST00000331471.8
bestrophin 3
chr19_+_35030626 4.75 ENST00000638536.1
sodium voltage-gated channel beta subunit 1
chr3_+_35639515 4.70 ENST00000684406.1
cAMP regulated phosphoprotein 21
chr3_+_35679614 4.68 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr19_+_35030711 4.65 ENST00000595652.5
sodium voltage-gated channel beta subunit 1
chr1_+_167936559 4.65 ENST00000432587.6
ENST00000367843.7
ENST00000312263.10
DDB1 and CUL4 associated factor 6
chr10_+_122192442 4.63 ENST00000514539.5
transforming acidic coiled-coil containing protein 2
chr11_+_10455292 4.59 ENST00000396553.6
adenosine monophosphate deaminase 3
chr3_-_52834901 4.58 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr16_+_7332744 4.53 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr22_+_17369420 4.50 ENST00000262608.13
ENST00000342247.10
CECR2 histone acetyl-lysine reader
chr2_+_232539683 4.43 ENST00000651502.1
cholinergic receptor nicotinic gamma subunit
chr10_+_119029711 4.42 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr10_+_122163672 4.37 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr17_-_82840010 4.35 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr2_+_232539720 4.33 ENST00000389492.3
cholinergic receptor nicotinic gamma subunit
chr5_-_181205182 4.33 ENST00000274773.12
tripartite motif containing 7
chr10_+_122163590 4.30 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr3_-_52835011 4.30 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr9_+_34992849 4.27 ENST00000443266.2
DnaJ heat shock protein family (Hsp40) member B5
chr4_+_3463300 4.22 ENST00000340083.6
ENST00000507039.5
ENST00000643608.1
docking protein 7
chr3_+_159852933 4.17 ENST00000482804.1
schwannomin interacting protein 1
chr3_+_42149222 4.10 ENST00000449246.5
ENST00000613405.4
trafficking kinesin protein 1
chr1_-_154870264 4.07 ENST00000618040.4
ENST00000271915.9
potassium calcium-activated channel subfamily N member 3
chr6_+_30884063 4.04 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
discoidin domain receptor tyrosine kinase 1
chr13_+_75760659 3.97 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr12_-_122422662 3.94 ENST00000620786.5
CAP-Gly domain containing linker protein 1
chr6_-_127459364 3.93 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr11_-_45286265 3.93 ENST00000020926.8
synaptotagmin 13
chr5_-_59039454 3.92 ENST00000358923.10
phosphodiesterase 4D
chr7_+_107660819 3.92 ENST00000644269.2
solute carrier family 26 member 4
chr19_-_48719712 3.89 ENST00000599703.1
ENST00000318083.11
MEF2 activating motif and SAP domain containing transcriptional regulator
chr2_-_113278898 3.89 ENST00000554830.2
ENST00000263335.11
ENST00000348715.9
ENST00000397647.7
ENST00000681162.1
ENST00000263334.9
ENST00000429538.8
paired box 8
chr10_-_60389833 3.86 ENST00000280772.7
ankyrin 3
chr12_-_69699382 3.85 ENST00000551160.5
bestrophin 3
chr1_+_15736251 3.85 ENST00000294454.6
solute carrier family 25 member 34
chr10_+_122163426 3.83 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr12_-_48999363 3.81 ENST00000421952.3
dendrin
chr7_+_107661002 3.80 ENST00000440056.1
solute carrier family 26 member 4
chr12_-_122422544 3.79 ENST00000358808.6
ENST00000361654.8
ENST00000539080.1
ENST00000537178.5
CAP-Gly domain containing linker protein 1
chr2_-_219253909 3.68 ENST00000248437.9
tubulin alpha 4a
chr17_+_78168565 3.55 ENST00000225777.8
ENST00000585591.5
ENST00000589711.1
ENST00000588282.5
ENST00000589168.1
synaptogyrin 2
chr13_+_75760431 3.50 ENST00000321797.12
LIM domain 7
chr6_+_30884353 3.46 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
discoidin domain receptor tyrosine kinase 1
chr10_-_73433550 3.42 ENST00000299432.7
MSS51 mitochondrial translational activator
chr2_-_219571241 3.42 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
obscurin like cytoskeletal adaptor 1
chr1_-_154192058 3.40 ENST00000271850.11
ENST00000368530.7
ENST00000651641.1
tropomyosin 3
chr4_-_44651619 3.34 ENST00000415895.9
ENST00000332990.6
Yip1 domain family member 7
chr9_+_89605004 3.30 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr1_+_99850485 3.23 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chrX_+_131058340 3.20 ENST00000276211.10
ENST00000370922.5
Rho GTPase activating protein 36
chr18_+_7231125 3.20 ENST00000383467.2
leucine rich repeat containing 30
chr5_-_60488055 3.17 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
phosphodiesterase 4D
chr8_-_143943911 3.16 ENST00000354589.7
plectin
chr14_+_24132050 3.16 ENST00000559294.1
fat storage inducing transmembrane protein 1
chr17_+_78169127 3.12 ENST00000590201.1
synaptogyrin 2
chrX_+_150983299 3.11 ENST00000325307.12
high mobility group box 3
chr11_+_111912725 3.10 ENST00000304298.4
heat shock protein family B (small) member 2
chr5_-_181205284 3.07 ENST00000334421.5
tripartite motif containing 7
chrX_-_107775951 3.04 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr1_+_99850348 3.03 ENST00000361915.8
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr17_+_41265339 3.02 ENST00000391355.1
keratin associated protein 9-6
chr5_-_151087660 2.99 ENST00000522226.5
TNFAIP3 interacting protein 1
chr3_+_35639589 2.99 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr8_-_140457719 2.97 ENST00000438773.4
trafficking protein particle complex 9
chr7_+_141074038 2.94 ENST00000565468.6
ENST00000610315.1
transmembrane protein 178B
chr6_+_30880780 2.93 ENST00000460944.6
ENST00000324771.12
discoidin domain receptor tyrosine kinase 1
chr12_-_6375556 2.87 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chr17_-_47957824 2.87 ENST00000300557.3
proline rich 15 like
chr3_+_32106612 2.87 ENST00000282541.10
ENST00000425459.5
ENST00000431009.1
glycerol-3-phosphate dehydrogenase 1 like
chr2_-_219254558 2.83 ENST00000392088.6
tubulin alpha 4a
chr6_-_46015812 2.82 ENST00000544153.3
ENST00000339561.12
chloride intracellular channel 5
chr14_+_67619911 2.82 ENST00000261783.4
arginase 2
chrX_-_33339525 2.82 ENST00000288447.9
dystrophin
chr17_-_42979993 2.79 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chr18_+_58255433 2.75 ENST00000635997.1
NEDD4 like E3 ubiquitin protein ligase
chr11_+_27041313 2.73 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr12_-_46832370 2.72 ENST00000546940.1
solute carrier family 38 member 4
chr19_-_45782479 2.70 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr17_-_7313620 2.70 ENST00000573684.5
G protein pathway suppressor 2
chr6_-_75493773 2.69 ENST00000237172.12
filamin A interacting protein 1
chr1_+_117606040 2.63 ENST00000369448.4
terminal nucleotidyltransferase 5C
chr17_+_47531052 2.60 ENST00000532729.6
ENST00000322157.9
aminopeptidase puromycin sensitive
chr6_-_75493629 2.58 ENST00000393004.6
filamin A interacting protein 1
chr12_+_50104000 2.58 ENST00000548814.1
ENST00000301149.8
glycerol-3-phosphate dehydrogenase 1
chr8_-_22156741 2.56 ENST00000424267.6
leucine rich repeat LGI family member 3
chr17_+_47531144 2.54 ENST00000677120.1
ENST00000677370.1
aminopeptidase puromycin sensitive
chr16_+_7332839 2.49 ENST00000355637.9
RNA binding fox-1 homolog 1
chr11_+_27040826 2.43 ENST00000533566.5
gamma-butyrobetaine hydroxylase 1
chr5_-_151087131 2.41 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNFAIP3 interacting protein 1
chr16_-_46831134 2.40 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr2_-_219253145 2.38 ENST00000456818.5
ENST00000447205.1
tubulin alpha 4a
chr12_-_6375209 2.36 ENST00000360168.7
sodium channel epithelial 1 subunit alpha
chr17_-_35088818 2.35 ENST00000414419.6
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr15_+_85582889 2.30 ENST00000560340.5
A-kinase anchoring protein 13
chr18_+_36297661 2.29 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr17_-_57955242 2.29 ENST00000577840.5
CUE domain containing 1
chr18_+_58045642 2.27 ENST00000676223.1
ENST00000675147.1
NEDD4 like E3 ubiquitin protein ligase
chr1_-_207032749 2.26 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chrX_-_154409246 2.26 ENST00000369807.6
deoxyribonuclease 1 like 1
chr4_+_105895458 2.26 ENST00000379987.7
nephronectin
chr11_+_27040725 2.25 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr5_+_140175205 2.23 ENST00000644078.1
cysteine rich transmembrane module containing 1
chr4_+_105895487 2.23 ENST00000506666.5
ENST00000503451.5
nephronectin
chr8_-_22156789 2.23 ENST00000306317.7
leucine rich repeat LGI family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MYOD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 49.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
6.4 19.2 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
5.3 15.9 GO:0007525 somatic muscle development(GO:0007525)
4.4 39.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
3.4 20.2 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
3.0 26.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
2.4 31.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.0 30.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.6 105.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.6 9.4 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
1.5 25.7 GO:0006600 creatine metabolic process(GO:0006600)
1.4 15.2 GO:0032264 IMP salvage(GO:0032264)
1.4 5.4 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3 6.7 GO:0097195 pilomotor reflex(GO:0097195)
1.3 7.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
1.2 5.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.2 3.7 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.2 27.8 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.1 12.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.1 17.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 17.9 GO:0071313 cellular response to caffeine(GO:0071313)
1.0 3.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.0 4.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
1.0 5.0 GO:1903028 positive regulation of opsonization(GO:1903028)
1.0 3.9 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.9 15.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.9 8.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8 15.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.7 4.5 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7 0.7 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.7 2.9 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) protein localization to basolateral plasma membrane(GO:1903361) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 2.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.7 2.8 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.7 1.3 GO:0010266 response to vitamin B1(GO:0010266)
0.7 21.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.6 11.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.6 7.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 5.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.6 3.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 10.6 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.6 1.8 GO:0003032 detection of oxygen(GO:0003032)
0.6 7.7 GO:0015705 iodide transport(GO:0015705)
0.6 7.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.5 6.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.5 5.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.5 3.9 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 8.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.5 11.6 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.4 3.1 GO:0018032 protein amidation(GO:0018032)
0.4 1.3 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.4 7.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4 1.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 2.6 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.4 1.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 8.4 GO:0045475 locomotor rhythm(GO:0045475)
0.4 2.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.4 1.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.4 21.4 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.4 3.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.4 14.9 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.4 1.5 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.4 4.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.4 17.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.4 0.7 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.4 3.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 1.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.3 1.3 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 3.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 6.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 5.0 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.3 1.0 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 2.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 0.8 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.3 5.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 1.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 4.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.9 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.2 1.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 3.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 6.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 1.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 1.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.2 0.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.2 0.5 GO:0036255 response to methylamine(GO:0036255) response to lipoic acid(GO:1903442)
0.2 1.4 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 1.9 GO:0015840 urea transport(GO:0015840)
0.2 2.8 GO:0000050 urea cycle(GO:0000050)
0.2 1.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 16.6 GO:0030239 myofibril assembly(GO:0030239)
0.2 8.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.1 GO:0032439 endosome localization(GO:0032439)
0.2 0.6 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 1.2 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 8.9 GO:0006308 DNA catabolic process(GO:0006308)
0.1 6.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 19.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 2.6 GO:0050881 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.1 1.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 13.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.4 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 25.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 2.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 4.6 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.5 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 1.4 GO:0051450 myoblast proliferation(GO:0051450)
0.1 4.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 1.2 GO:0060073 micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.1 2.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 1.0 GO:0015811 L-cystine transport(GO:0015811)
0.1 1.5 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 1.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 7.7 GO:0051693 actin filament capping(GO:0051693)
0.1 2.9 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 2.6 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1 1.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 18.8 GO:0043271 negative regulation of ion transport(GO:0043271)
0.1 3.5 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.4 GO:0023021 termination of signal transduction(GO:0023021)
0.1 5.1 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 4.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.0 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 7.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.1 18.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.0 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 10.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 6.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.5 GO:0021678 third ventricle development(GO:0021678)
0.1 2.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 1.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.1 GO:0045213 ERBB3 signaling pathway(GO:0038129) neurotransmitter receptor metabolic process(GO:0045213)
0.1 3.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 8.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 1.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108) negative regulation of mesoderm development(GO:2000381)
0.1 0.6 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 3.0 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 10.8 GO:0021987 cerebral cortex development(GO:0021987)
0.0 2.4 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 1.4 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.7 GO:0015074 DNA integration(GO:0015074)
0.0 1.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.6 GO:0015747 urate transport(GO:0015747)
0.0 0.5 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664)
0.0 0.2 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 1.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 7.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 6.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.8 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0007028 cytoplasm organization(GO:0007028)
0.0 2.4 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.7 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 2.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 6.7 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 3.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 7.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 4.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.7 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.7 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 1.0 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.0 0.8 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.7 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.4 GO:0090179 regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 1.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 2.9 GO:0032392 DNA geometric change(GO:0032392)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 14.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 6.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.4 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.7 GO:0071806 protein transmembrane transport(GO:0071806)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.8 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 1.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.1 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.9 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 66.6 GO:0005861 troponin complex(GO:0005861)
2.0 33.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.9 9.5 GO:0042643 actomyosin, actin portion(GO:0042643)
1.8 91.5 GO:0005859 muscle myosin complex(GO:0005859)
1.5 12.1 GO:0030314 junctional membrane complex(GO:0030314)
1.5 48.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.4 19.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.3 46.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.3 15.8 GO:0097512 cardiac myofibril(GO:0097512)
1.3 3.8 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
1.0 3.1 GO:0018444 translation release factor complex(GO:0018444)
1.0 12.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
1.0 6.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.8 2.4 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.8 5.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 2.0 GO:0097513 myosin II filament(GO:0097513)
0.6 15.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 38.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.5 16.9 GO:0034706 sodium channel complex(GO:0034706)
0.5 10.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 25.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 8.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 131.1 GO:0030017 sarcomere(GO:0030017)
0.3 2.6 GO:1990635 proximal dendrite(GO:1990635)
0.3 6.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.3 30.8 GO:0034707 chloride channel complex(GO:0034707)
0.2 3.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 13.0 GO:0031941 filamentous actin(GO:0031941)
0.2 4.7 GO:0016528 sarcoplasm(GO:0016528)
0.2 2.8 GO:0070187 telosome(GO:0070187)
0.2 4.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 2.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.2 GO:0031417 NatC complex(GO:0031417)
0.2 3.0 GO:0030008 TRAPP complex(GO:0030008)
0.2 5.3 GO:0097440 apical dendrite(GO:0097440)
0.2 2.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 2.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.1 GO:0060091 kinocilium(GO:0060091)
0.1 0.7 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.9 GO:0060171 stereocilium membrane(GO:0060171)
0.1 4.0 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 6.2 GO:0016459 myosin complex(GO:0016459)
0.1 5.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.6 GO:0097487 platelet dense granule membrane(GO:0031088) multivesicular body, internal vesicle(GO:0097487)
0.1 4.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 7.3 GO:0045095 keratin filament(GO:0045095)
0.1 1.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 7.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 5.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 5.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 2.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 3.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 2.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 2.6 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 6.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 56.3 GO:0031014 troponin T binding(GO:0031014)
3.7 36.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
3.2 26.0 GO:0004111 creatine kinase activity(GO:0004111)
2.1 16.7 GO:0051373 FATZ binding(GO:0051373)
1.9 9.4 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.9 7.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.7 5.0 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
1.7 6.6 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
1.6 48.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
1.5 15.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.3 43.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
1.3 7.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
1.3 3.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.2 12.0 GO:0004126 cytidine deaminase activity(GO:0004126)
1.2 26.7 GO:0005344 oxygen transporter activity(GO:0005344)
1.1 139.4 GO:0008307 structural constituent of muscle(GO:0008307)
1.1 27.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.0 2.9 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.9 8.0 GO:0043426 MRF binding(GO:0043426)
0.9 15.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.8 5.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.8 4.6 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.7 2.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.7 3.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 6.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.5 3.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 3.9 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.5 2.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 3.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.4 7.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 15.5 GO:0030506 ankyrin binding(GO:0030506)
0.4 2.6 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.4 1.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.4 34.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.4 3.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.4 8.9 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.3 4.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 6.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.3 1.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 1.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.3 20.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.3 13.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 8.4 GO:0043495 protein anchor(GO:0043495)
0.3 3.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 2.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 5.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 11.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 18.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 7.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 2.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 19.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 5.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 32.3 GO:0005254 chloride channel activity(GO:0005254)
0.2 3.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 6.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.6 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 5.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 0.5 GO:0070279 glycine dehydrogenase (decarboxylating) activity(GO:0004375) oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor(GO:0016642) vitamin B6 binding(GO:0070279) pyridoxal binding(GO:0070280)
0.1 8.8 GO:0030332 cyclin binding(GO:0030332)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.7 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 6.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 2.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 4.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 4.3 GO:0005521 lamin binding(GO:0005521)
0.1 1.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 6.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 3.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.0 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 9.8 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.1 10.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 25.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 2.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.1 60.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 12.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 2.6 GO:0070628 proteasome binding(GO:0070628)
0.1 4.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 19.5 GO:0051015 actin filament binding(GO:0051015)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.9 GO:0017022 myosin binding(GO:0017022)
0.1 1.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 9.0 GO:0051117 ATPase binding(GO:0051117)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 1.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 5.7 GO:0031072 heat shock protein binding(GO:0031072)
0.1 4.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0051431 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 13.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 4.5 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.7 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 6.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 12.3 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 1.1 GO:0005123 death receptor binding(GO:0005123)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 2.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 2.0 GO:0051287 NAD binding(GO:0051287)
0.0 4.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) peptide antigen binding(GO:0042605)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.8 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 40.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 28.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 44.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 22.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 9.4 PID AURORA B PATHWAY Aurora B signaling
0.1 5.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 3.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 5.9 PID FOXO PATHWAY FoxO family signaling
0.1 5.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 2.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.8 PID ATM PATHWAY ATM pathway
0.1 0.6 PID MYC PATHWAY C-MYC pathway
0.1 2.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 3.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 3.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 48.0 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
2.0 145.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.0 57.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 15.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 9.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 3.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.2 6.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 11.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 3.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 6.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 15.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 8.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 5.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 33.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 5.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 27.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.3 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 7.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL