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Illumina Body Map 2 (GSE30611)

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Results for NFAT5

Z-value: 0.70

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Transcription factors associated with NFAT5

Gene Symbol Gene ID Gene Info
NFAT5
ENSG00000102908.22 nuclear factor of activated T cells 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFAT5hg38_v1_chr16_+_69566314_695663450.441.1e-02Click!

Activity profile of NFAT5 motif

Sorted Z-values of NFAT5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111923722 2.54 ENST00000527950.5
CRYAB
crystallin alpha B
chr12_+_101594849 2.34 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
MYBPC1
myosin binding protein C1
chr10_+_3104676 2.08 ENST00000415005.6
ENST00000468050.1
PFKP
phosphofructokinase, platelet
chr11_+_131370478 1.84 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
NTM
neurotrimin
chr1_+_159204860 1.82 ENST00000368122.4
ENST00000368121.6
ACKR1
atypical chemokine receptor 1 (Duffy blood group)
chr13_-_67230377 1.61 ENST00000544246.5
ENST00000377861.4
PCDH9
protocadherin 9
chr22_-_37984534 1.59 ENST00000396884.8
SOX10
SRY-box transcription factor 10
chr13_-_67230313 1.50 ENST00000377865.7
PCDH9
protocadherin 9
chr6_-_53665748 1.45 ENST00000370905.4
KLHL31
kelch like family member 31
chr6_+_152750789 1.44 ENST00000367244.8
ENST00000367243.7
VIP
vasoactive intestinal peptide
chr2_-_160200251 1.27 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
ITGB6
integrin subunit beta 6
chr15_+_43593054 1.24 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr1_-_201377652 1.23 ENST00000455702.6
ENST00000367320.6
ENST00000421663.6
ENST00000412633.3
ENST00000367318.10
ENST00000422165.6
ENST00000656932.1
ENST00000438742.6
ENST00000367322.6
ENST00000458432.6
ENST00000509001.5
ENST00000660295.1
TNNT2
troponin T2, cardiac type
chr19_-_49155130 1.13 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr3_-_116445458 1.10 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr6_+_150143018 1.06 ENST00000361131.5
PPP1R14C
protein phosphatase 1 regulatory inhibitor subunit 14C
chr2_-_160200310 1.03 ENST00000620391.4
ITGB6
integrin subunit beta 6
chr4_+_119027335 1.02 ENST00000627783.2
SYNPO2
synaptopodin 2
chr14_+_91114026 1.01 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
DGLUCY
D-glutamate cyclase
chr11_+_131911396 1.01 ENST00000425719.6
ENST00000374784.5
NTM
neurotrimin
chr3_-_116444983 0.94 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr10_+_6163818 0.93 ENST00000639949.1
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_-_45782479 0.93 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DMPK
DM1 protein kinase
chr5_+_149581368 0.90 ENST00000333677.7
ARHGEF37
Rho guanine nucleotide exchange factor 37
chr11_+_73648674 0.87 ENST00000535129.5
PLEKHB1
pleckstrin homology domain containing B1
chrX_-_45200828 0.85 ENST00000398000.7
DIPK2B
divergent protein kinase domain 2B
chr9_+_68356603 0.84 ENST00000396396.6
PGM5
phosphoglucomutase 5
chr14_-_25010604 0.84 ENST00000550887.5
STXBP6
syntaxin binding protein 6
chr18_-_36122110 0.83 ENST00000586829.1
SLC39A6
solute carrier family 39 member 6
chr20_+_36091409 0.73 ENST00000202028.9
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr17_+_34356472 0.73 ENST00000225844.7
CCL13
C-C motif chemokine ligand 13
chr20_+_34516394 0.73 ENST00000357156.7
ENST00000300469.13
ENST00000374846.3
DYNLRB1
dynein light chain roadblock-type 1
chr19_+_41708585 0.71 ENST00000398599.8
ENST00000221992.11
CEACAM5
CEA cell adhesion molecule 5
chr19_+_859654 0.71 ENST00000592860.2
ENST00000327726.11
CFD
complement factor D
chr5_-_79512794 0.69 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chr17_+_9842469 0.68 ENST00000304773.5
GLP2R
glucagon like peptide 2 receptor
chr7_+_149872955 0.66 ENST00000421974.7
ENST00000456496.7
ATP6V0E2
ATPase H+ transporting V0 subunit e2
chr18_+_10454584 0.66 ENST00000355285.10
APCDD1
APC down-regulated 1
chr12_+_26121984 0.65 ENST00000538142.5
SSPN
sarcospan
chr3_+_69762703 0.64 ENST00000433517.5
MITF
melanocyte inducing transcription factor
chr10_-_67696115 0.63 ENST00000433211.7
CTNNA3
catenin alpha 3
chr14_+_91114431 0.62 ENST00000428926.6
ENST00000517362.5
DGLUCY
D-glutamate cyclase
chr6_+_116511626 0.62 ENST00000368599.4
CALHM5
calcium homeostasis modulator family member 5
chr1_-_114757958 0.61 ENST00000525132.1
CSDE1
cold shock domain containing E1
chr14_-_59630806 0.61 ENST00000342503.8
RTN1
reticulon 1
chr15_+_48878070 0.60 ENST00000530028.3
ENST00000560490.1
EID1
EP300 interacting inhibitor of differentiation 1
chr14_+_91114388 0.60 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
DGLUCY
D-glutamate cyclase
chrX_-_57137523 0.60 ENST00000614076.1
ENST00000374906.3
SPIN2A
spindlin family member 2A
chr14_+_91114667 0.60 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
DGLUCY
D-glutamate cyclase
chr9_+_136807911 0.59 ENST00000371671.9
ENST00000311502.12
ENST00000371663.10
RABL6
RAB, member RAS oncogene family like 6
chr1_+_111346590 0.59 ENST00000369737.4
ENST00000369738.9
PIFO
primary cilia formation
chr1_+_11654368 0.57 ENST00000251546.8
FBXO44
F-box protein 44
chr14_+_91114364 0.56 ENST00000518868.5
DGLUCY
D-glutamate cyclase
chr9_-_27005659 0.56 ENST00000380055.6
LRRC19
leucine rich repeat containing 19
chr17_+_70075215 0.56 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr1_-_114757971 0.56 ENST00000261443.9
ENST00000534699.5
ENST00000339438.10
ENST00000358528.9
ENST00000529046.5
ENST00000525970.5
ENST00000369530.5
ENST00000530886.5
ENST00000610726.4
CSDE1
cold shock domain containing E1
chr11_+_12377524 0.55 ENST00000334956.15
PARVA
parvin alpha
chr16_+_89921851 0.54 ENST00000554444.5
ENST00000556565.5
TUBB3
tubulin beta 3 class III
chr17_+_4950147 0.54 ENST00000522301.5
ENO3
enolase 3
chr3_-_18445565 0.54 ENST00000415069.5
SATB1
SATB homeobox 1
chr3_+_8501807 0.54 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LMCD1
LIM and cysteine rich domains 1
chr2_+_130963642 0.53 ENST00000409303.6
ARHGEF4
Rho guanine nucleotide exchange factor 4
chrX_+_136497586 0.52 ENST00000218364.5
HTATSF1
HIV-1 Tat specific factor 1
chr19_-_45782388 0.51 ENST00000458663.6
DMPK
DM1 protein kinase
chr22_-_29315656 0.51 ENST00000401450.3
ENST00000216101.7
RASL10A
RAS like family 10 member A
chr5_+_140806929 0.50 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
PCDHA4
protocadherin alpha 4
chr2_+_48568981 0.50 ENST00000394754.5
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr19_-_54364908 0.48 ENST00000391742.7
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr2_-_160200289 0.46 ENST00000409872.1
ITGB6
integrin subunit beta 6
chr12_-_75209814 0.44 ENST00000549446.6
KCNC2
potassium voltage-gated channel subfamily C member 2
chr9_-_34589716 0.42 ENST00000378980.8
CNTFR
ciliary neurotrophic factor receptor
chr19_+_17795129 0.42 ENST00000600777.1
ENST00000318683.7
ENST00000595387.1
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr17_+_70075317 0.42 ENST00000589377.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr15_-_48878001 0.41 ENST00000558220.1
ENST00000537958.5
SHC4
SHC adaptor protein 4
chr12_-_75209701 0.40 ENST00000350228.6
ENST00000298972.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr8_-_102238874 0.39 ENST00000519962.5
ENST00000519317.5
ENST00000395912.6
RRM2B
ribonucleotide reductase regulatory TP53 inducible subunit M2B
chr6_+_101393699 0.39 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr8_-_102238769 0.39 ENST00000621845.1
ENST00000522368.5
RRM2B
ribonucleotide reductase regulatory TP53 inducible subunit M2B
chr2_+_108377947 0.38 ENST00000272452.7
SULT1C4
sulfotransferase family 1C member 4
chr7_-_93226449 0.37 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr9_-_34589701 0.37 ENST00000351266.8
CNTFR
ciliary neurotrophic factor receptor
chr8_-_102238903 0.35 ENST00000251810.8
RRM2B
ribonucleotide reductase regulatory TP53 inducible subunit M2B
chr14_-_59630582 0.35 ENST00000395090.5
RTN1
reticulon 1
chr19_+_41708635 0.35 ENST00000617332.4
ENST00000615021.4
ENST00000616453.1
ENST00000405816.5
ENST00000435837.2
CEACAM5
ENSG00000267881.2
CEA cell adhesion molecule 5
novel protein, readthrough between CEACAM5-CEACAM6
chr2_-_206159410 0.34 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr1_-_11654422 0.34 ENST00000354287.5
FBXO2
F-box protein 2
chr12_+_4269771 0.33 ENST00000676411.1
CCND2
cyclin D2
chr5_+_141213919 0.33 ENST00000341948.6
PCDHB13
protocadherin beta 13
chr6_-_46954922 0.31 ENST00000265417.7
ADGRF5
adhesion G protein-coupled receptor F5
chr7_-_101245032 0.31 ENST00000442303.1
FIS1
fission, mitochondrial 1
chr11_+_57181945 0.31 ENST00000497933.3
LRRC55
leucine rich repeat containing 55
chr8_-_27611866 0.30 ENST00000519742.5
CLU
clusterin
chr5_+_151212117 0.28 ENST00000523466.5
GM2A
GM2 ganglioside activator
chrX_-_154354889 0.28 ENST00000438732.2
FLNA
filamin A
chr14_-_21580076 0.27 ENST00000641040.1
ENST00000641185.1
OR10G3
olfactory receptor family 10 subfamily G member 3
chr3_+_48989876 0.27 ENST00000343546.8
P4HTM
prolyl 4-hydroxylase, transmembrane
chr8_+_49911604 0.26 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
SNTG1
syntrophin gamma 1
chr19_-_54364983 0.25 ENST00000434277.6
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr10_+_110207587 0.25 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr2_-_19901624 0.25 ENST00000431392.1
TTC32
tetratricopeptide repeat domain 32
chr3_-_149576203 0.24 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr3_+_8501846 0.24 ENST00000454244.4
LMCD1
LIM and cysteine rich domains 1
chr2_+_241869722 0.24 ENST00000343216.3
RTP5
receptor transporter protein 5 (putative)
chr7_-_101245056 0.24 ENST00000223136.5
FIS1
fission, mitochondrial 1
chr4_-_106238690 0.23 ENST00000503516.1
TBCK
TBC1 domain containing kinase
chr3_+_69763726 0.22 ENST00000448226.9
MITF
melanocyte inducing transcription factor
chr5_-_78549151 0.22 ENST00000515007.6
LHFPL2
LHFPL tetraspan subfamily member 2
chr13_+_45120493 0.22 ENST00000340473.8
GTF2F2
general transcription factor IIF subunit 2
chr19_+_5914202 0.21 ENST00000588776.8
ENST00000588865.2
CAPS
calcyphosine
chr4_+_17577487 0.21 ENST00000606142.5
LAP3
leucine aminopeptidase 3
chr14_-_106389858 0.21 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr3_+_25428233 0.21 ENST00000437042.6
ENST00000330688.9
RARB
retinoic acid receptor beta
chrX_-_45200895 0.21 ENST00000377934.4
DIPK2B
divergent protein kinase domain 2B
chr10_-_27243019 0.20 ENST00000679293.1
ACBD5
acyl-CoA binding domain containing 5
chr6_-_130970428 0.20 ENST00000529208.5
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr2_-_206159509 0.20 ENST00000423725.5
NDUFS1
NADH:ubiquinone oxidoreductase core subunit S1
chr11_-_58844695 0.20 ENST00000287275.6
GLYATL2
glycine-N-acyltransferase like 2
chr19_-_54364807 0.19 ENST00000474878.5
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr4_+_17577190 0.19 ENST00000226299.9
ENST00000618908.4
LAP3
leucine aminopeptidase 3
chr1_-_246507237 0.19 ENST00000490107.6
SMYD3
SET and MYND domain containing 3
chr6_+_4889992 0.18 ENST00000343762.5
CDYL
chromodomain Y like
chr18_-_27185284 0.18 ENST00000580774.2
ENST00000618847.5
CHST9
carbohydrate sulfotransferase 9
chr7_+_148133684 0.18 ENST00000628930.2
CNTNAP2
contactin associated protein 2
chr17_+_41967783 0.18 ENST00000585452.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr5_+_140882116 0.17 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
PCDHA13
protocadherin alpha 13
chr11_-_62689523 0.17 ENST00000317449.5
LRRN4CL
LRRN4 C-terminal like
chr12_-_54981838 0.16 ENST00000316577.12
TESPA1
thymocyte expressed, positive selection associated 1
chr15_+_90902218 0.15 ENST00000558290.5
ENST00000558853.5
ENST00000559999.5
MAN2A2
mannosidase alpha class 2A member 2
chr14_+_99773698 0.15 ENST00000556199.1
EML1
EMAP like 1
chr8_+_49911396 0.14 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr4_+_86936386 0.14 ENST00000511442.1
AFF1
AF4/FMR2 family member 1
chr18_-_77127935 0.13 ENST00000581878.5
MBP
myelin basic protein
chr3_+_40505992 0.13 ENST00000420891.5
ENST00000314529.10
ENST00000418905.1
ZNF620
zinc finger protein 620
chr8_-_51408974 0.13 ENST00000522933.5
PXDNL
peroxidasin like
chr8_-_98942557 0.12 ENST00000523601.5
STK3
serine/threonine kinase 3
chr16_+_68539213 0.12 ENST00000570495.5
ENST00000564323.5
ENST00000562156.5
ENST00000573685.5
ENST00000563169.7
ENST00000611381.4
ZFP90
ZFP90 zinc finger protein
chr16_-_29505820 0.11 ENST00000550665.5
NPIPB12
nuclear pore complex interacting protein family member B12
chr14_-_102240597 0.11 ENST00000523231.5
ENST00000524370.5
ENST00000517966.5
MOK
MOK protein kinase
chr14_+_20138820 0.10 ENST00000641086.1
OR4N5
olfactory receptor family 4 subfamily N member 5
chr11_+_8911280 0.10 ENST00000530281.5
ENST00000396648.6
ENST00000534147.5
ENST00000529942.1
AKIP1
A-kinase interacting protein 1
chr19_-_54364863 0.10 ENST00000348231.8
LAIR1
leukocyte associated immunoglobulin like receptor 1
chr17_-_74592283 0.10 ENST00000375352.1
CD300LD
CD300 molecule like family member d
chr14_-_92121902 0.09 ENST00000329559.8
NDUFB1
NADH:ubiquinone oxidoreductase subunit B1
chrX_-_70931089 0.09 ENST00000374299.8
ENST00000298085.4
SLC7A3
solute carrier family 7 member 3
chr6_-_31958431 0.09 ENST00000625905.1
ENST00000454913.5
ENST00000436289.6
NELFE
negative elongation factor complex member E
chr14_+_100381974 0.09 ENST00000542471.2
WDR25
WD repeat domain 25
chr4_+_154743993 0.08 ENST00000336356.4
LRAT
lecithin retinol acyltransferase
chr10_+_70052806 0.08 ENST00000676609.1
ENST00000679349.1
ENST00000373255.9
ENST00000676608.1
ENST00000455786.1
MACROH2A2
macroH2A.2 histone
chr20_-_10431922 0.08 ENST00000399054.6
ENST00000609375.1
MKKS
ENSG00000285508.1
McKusick-Kaufman syndrome
novel protein
chr17_+_42798857 0.08 ENST00000588408.6
CNTD1
cyclin N-terminal domain containing 1
chr7_-_100100716 0.08 ENST00000354230.7
ENST00000425308.5
MCM7
minichromosome maintenance complex component 7
chr7_+_1086800 0.08 ENST00000413368.5
ENST00000397092.5
ENST00000297469.3
GPER1
G protein-coupled estrogen receptor 1
chr7_+_128758947 0.08 ENST00000493278.1
CALU
calumenin
chr2_+_237968770 0.08 ENST00000434655.5
ENST00000612130.4
UBE2F
ubiquitin conjugating enzyme E2 F (putative)
chr1_-_85404494 0.08 ENST00000633113.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_-_60139733 0.08 ENST00000506635.5
ANK3
ankyrin 3
chr9_-_77648303 0.07 ENST00000341700.7
GNA14
G protein subunit alpha 14
chr19_+_17309531 0.07 ENST00000359866.9
DDA1
DET1 and DDB1 associated 1
chr19_+_17794776 0.07 ENST00000599265.5
B3GNT3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr9_-_6015607 0.06 ENST00000485372.1
ENST00000259569.6
ENST00000623170.1
RANBP6
RAN binding protein 6
chr7_-_92528446 0.06 ENST00000248633.9
PEX1
peroxisomal biogenesis factor 1
chr7_-_92528433 0.06 ENST00000428214.5
ENST00000438045.5
PEX1
peroxisomal biogenesis factor 1
chr12_-_54973547 0.05 ENST00000526532.5
ENST00000532757.5
TESPA1
thymocyte expressed, positive selection associated 1
chr10_+_97849824 0.05 ENST00000370602.6
GOLGA7B
golgin A7 family member B
chr1_-_31919368 0.05 ENST00000457805.6
ENST00000602725.5
ENST00000679970.1
PTP4A2
ENSG00000288678.1
protein tyrosine phosphatase 4A2
novel protein
chr19_-_43596123 0.05 ENST00000422989.6
ENST00000598324.1
IRGQ
immunity related GTPase Q
chr17_+_47651061 0.05 ENST00000540627.5
KPNB1
karyopherin subunit beta 1
chr19_-_46784905 0.04 ENST00000594991.5
SLC1A5
solute carrier family 1 member 5
chr17_+_6755559 0.04 ENST00000574394.5
XAF1
XIAP associated factor 1
chr3_+_185282941 0.04 ENST00000448876.5
ENST00000446828.5
ENST00000447637.1
ENST00000424227.5
ENST00000454237.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr3_+_63819368 0.04 ENST00000616659.1
C3orf49
chromosome 3 open reading frame 49
chr9_+_133376334 0.04 ENST00000371957.4
STKLD1
serine/threonine kinase like domain containing 1
chr2_-_55296361 0.03 ENST00000647547.1
CCDC88A
coiled-coil domain containing 88A
chr22_+_37849437 0.03 ENST00000406934.5
ENST00000451427.1
EIF3L
eukaryotic translation initiation factor 3 subunit L
chr12_-_11062294 0.03 ENST00000533467.1
TAS2R46
taste 2 receptor member 46
chr17_+_27471999 0.03 ENST00000583370.5
ENST00000509603.6
ENST00000268763.10
ENST00000398988.7
KSR1
kinase suppressor of ras 1
chr1_+_173824956 0.03 ENST00000648458.1
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr17_-_42798680 0.03 ENST00000328434.8
COA3
cytochrome c oxidase assembly factor 3
chr10_+_79841358 0.03 ENST00000602967.5
NUTM2E
NUT family member 2E
chr16_+_33009175 0.03 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr2_-_222298974 0.03 ENST00000392069.6
ENST00000392070.7
PAX3
paired box 3
chr20_-_23751256 0.02 ENST00000398402.1
CST1
cystatin SN
chr13_+_101489940 0.01 ENST00000376162.7
ITGBL1
integrin subunit beta like 1
chr1_-_246507312 0.01 ENST00000403792.7
SMYD3
SET and MYND domain containing 3
chr1_-_243254460 0.01 ENST00000522191.5
CEP170
centrosomal protein 170
chr3_+_122680850 0.01 ENST00000494811.2
PARP14
poly(ADP-ribose) polymerase family member 14
chr2_+_74549026 0.01 ENST00000409429.5
DOK1
docking protein 1
chr14_+_51847145 0.01 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr1_-_248682328 0.00 ENST00000342623.5
OR14I1
olfactory receptor family 14 subfamily I member 1
chr15_+_43593601 0.00 ENST00000449946.5
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr22_+_37849372 0.00 ENST00000624234.3
ENST00000381683.10
ENST00000652021.1
ENST00000414316.5
EIF3L
eukaryotic translation initiation factor 3 subunit L

Network of associatons between targets according to the STRING database.

First level regulatory network of NFAT5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.3 1.6 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.3 1.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.7 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) response to cyclosporin A(GO:1905237)
0.2 2.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.8 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 1.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 2.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 2.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.5 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 2.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.7 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.8 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 1.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.8 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 3.0 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.6 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 1.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.7 GO:0015991 vacuolar acidification(GO:0007035) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.8 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.0 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.3 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation(GO:0070145)
0.0 0.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 0.8 GO:0005914 spot adherens junction(GO:0005914)
0.2 3.8 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 1.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 2.3 GO:0032982 myosin filament(GO:0032982)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.6 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 1.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 3.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0008091 spectrin(GO:0008091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 1.2 GO:0030172 troponin C binding(GO:0030172)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 1.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.1 1.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.9 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 1.1 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.3 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 3.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 2.0 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815) aspartate-tRNA(Asn) ligase activity(GO:0050560)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 3.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors