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Illumina Body Map 2 (GSE30611)

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Results for NFE2L1

Z-value: 0.94

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
NFE2L1
ENSG00000082641.16 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg38_v1_chr17_+_48055945_48055986-0.576.6e-04Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_59019397 3.73 ENST00000217133.2
TUBB1
tubulin beta 1 class VI
chr1_+_192158448 3.07 ENST00000367460.4
RGS18
regulator of G protein signaling 18
chr2_-_157488829 2.71 ENST00000435117.1
ENST00000439355.5
CYTIP
cytohesin 1 interacting protein
chr7_+_142352802 2.66 ENST00000634605.1
TRBV7-2
T cell receptor beta variable 7-2
chr7_+_142469521 2.61 ENST00000390371.3
TRBV6-6
T cell receptor beta variable 6-6
chr4_+_73740541 2.39 ENST00000401931.1
ENST00000307407.8
CXCL8
C-X-C motif chemokine ligand 8
chr1_-_183569186 2.34 ENST00000420553.5
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr12_-_122716790 2.23 ENST00000528880.3
HCAR3
hydroxycarboxylic acid receptor 3
chr3_-_27722699 2.06 ENST00000461503.2
EOMES
eomesodermin
chr12_-_14951106 2.02 ENST00000541644.5
ENST00000545895.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr17_-_35880350 1.99 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
CCL5
C-C motif chemokine ligand 5
chr12_-_14950606 1.96 ENST00000536592.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr12_-_122703346 1.86 ENST00000328880.6
HCAR2
hydroxycarboxylic acid receptor 2
chr7_+_80638633 1.82 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr4_-_154590735 1.69 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chr16_+_72056153 1.65 ENST00000576168.6
ENST00000567185.7
ENST00000567612.2
HP
haptoglobin
chr11_+_60455839 1.65 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
MS4A1
membrane spanning 4-domains A1
chr7_+_80638662 1.61 ENST00000394788.7
CD36
CD36 molecule
chr7_+_80646436 1.60 ENST00000419819.2
CD36
CD36 molecule
chrX_+_124346544 1.55 ENST00000371139.9
SH2D1A
SH2 domain containing 1A
chr12_-_52493250 1.54 ENST00000330722.7
KRT6A
keratin 6A
chr9_-_114930508 1.53 ENST00000223795.3
ENST00000618336.4
TNFSF8
TNF superfamily member 8
chr14_+_22147988 1.52 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr7_+_80646347 1.49 ENST00000413265.5
CD36
CD36 molecule
chr7_+_142618821 1.46 ENST00000390393.3
TRBV19
T cell receptor beta variable 19
chr14_+_21887848 1.45 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr6_-_132734692 1.44 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
VNN3
vanin 3
chr19_-_54100792 1.43 ENST00000391761.5
ENST00000356532.7
ENST00000616447.4
ENST00000359649.8
ENST00000358375.8
ENST00000391760.1
ENST00000351806.8
OSCAR
osteoclast associated Ig-like receptor
chr16_+_31355215 1.39 ENST00000562522.2
ITGAX
integrin subunit alpha X
chr6_+_144150492 1.38 ENST00000367568.5
STX11
syntaxin 11
chr14_+_22462932 1.36 ENST00000390477.2
TRDC
T cell receptor delta constant
chr16_+_31355165 1.35 ENST00000562918.5
ENST00000268296.9
ITGAX
integrin subunit alpha X
chr5_+_169695135 1.35 ENST00000523684.5
ENST00000519734.5
DOCK2
dedicator of cytokinesis 2
chr7_+_142313144 1.34 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chrX_+_124346525 1.33 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr10_+_69088096 1.30 ENST00000242465.4
SRGN
serglycin
chr7_+_80646305 1.28 ENST00000426978.5
ENST00000432207.5
CD36
CD36 molecule
chr18_+_3252208 1.27 ENST00000578562.6
MYL12A
myosin light chain 12A
chr2_-_196176467 1.27 ENST00000409228.5
STK17B
serine/threonine kinase 17b
chr20_-_36646146 1.27 ENST00000262866.9
SLA2
Src like adaptor 2
chr6_+_158649997 1.26 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
SYTL3
synaptotagmin like 3
chr14_-_22815421 1.26 ENST00000674313.1
ENST00000555959.1
SLC7A7
solute carrier family 7 member 7
chr5_-_177509814 1.26 ENST00000510898.7
ENST00000502885.5
ENST00000506493.5
DOK3
docking protein 3
chr13_-_99307387 1.24 ENST00000376414.5
GPR183
G protein-coupled receptor 183
chr3_-_115071333 1.20 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_169069537 1.19 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
DHRS9
dehydrogenase/reductase 9
chr11_+_35176696 1.18 ENST00000528455.5
CD44
CD44 molecule (Indian blood group)
chr2_-_196176320 1.18 ENST00000420683.1
STK17B
serine/threonine kinase 17b
chr18_+_3252267 1.15 ENST00000536605.1
ENST00000580887.5
MYL12A
myosin light chain 12A
chr19_-_54242751 1.15 ENST00000245621.6
ENST00000396365.6
LILRA6
leukocyte immunoglobulin like receptor A6
chr4_+_73853290 1.14 ENST00000226524.4
PF4V1
platelet factor 4 variant 1
chr17_-_66220630 1.13 ENST00000585162.1
APOH
apolipoprotein H
chr12_-_9999176 1.13 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr1_+_198638457 1.12 ENST00000367379.6
PTPRC
protein tyrosine phosphatase receptor type C
chr12_-_54419259 1.11 ENST00000293379.9
ITGA5
integrin subunit alpha 5
chr11_+_35176639 1.11 ENST00000527889.6
CD44
CD44 molecule (Indian blood group)
chr15_+_88639009 1.10 ENST00000306072.10
ISG20
interferon stimulated exonuclease gene 20
chr11_+_35180342 1.10 ENST00000639002.1
CD44
CD44 molecule (Indian blood group)
chr14_+_21997531 1.10 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr11_+_35176575 1.07 ENST00000526000.6
CD44
CD44 molecule (Indian blood group)
chr19_-_43656616 1.07 ENST00000593447.5
PLAUR
plasminogen activator, urokinase receptor
chr7_+_142424942 1.05 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr7_+_142615710 1.05 ENST00000611520.1
TRBV18
T cell receptor beta variable 18
chr21_-_14546297 1.04 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_+_35189869 1.04 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44
CD44 molecule (Indian blood group)
chr1_+_198638968 1.02 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
PTPRC
protein tyrosine phosphatase receptor type C
chr19_-_42217667 1.01 ENST00000336034.8
ENST00000596251.6
ENST00000598200.1
ENST00000598727.5
DEDD2
death effector domain containing 2
chr11_+_35176611 1.01 ENST00000279452.10
CD44
CD44 molecule (Indian blood group)
chr15_-_60391127 1.01 ENST00000559350.5
ENST00000558986.5
ENST00000560389.5
ANXA2
annexin A2
chr1_-_173917281 1.01 ENST00000367698.4
SERPINC1
serpin family C member 1
chr4_-_15681454 1.00 ENST00000507899.1
ENST00000510802.5
FBXL5
F-box and leucine rich repeat protein 5
chr14_+_51847116 1.00 ENST00000553560.5
GNG2
G protein subunit gamma 2
chr9_-_125484490 1.00 ENST00000444226.1
MAPKAP1
MAPK associated protein 1
chr14_+_22271921 0.99 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr14_+_22070548 0.98 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr5_-_177509843 0.98 ENST00000510380.5
ENST00000357198.9
DOK3
docking protein 3
chr2_+_218400039 0.98 ENST00000452977.5
CTDSP1
CTD small phosphatase 1
chr2_+_201129483 0.97 ENST00000440180.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr14_+_22226711 0.96 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr17_-_31318818 0.95 ENST00000578584.5
ENSG00000265118.5
novel protein
chr1_+_241532121 0.93 ENST00000366558.7
KMO
kynurenine 3-monooxygenase
chr2_+_169066994 0.92 ENST00000357546.6
ENST00000432060.6
DHRS9
dehydrogenase/reductase 9
chr18_-_69947415 0.92 ENST00000577287.5
CD226
CD226 molecule
chr7_+_142626642 0.92 ENST00000390394.3
TRBV20-1
T cell receptor beta variable 20-1
chr14_+_20781139 0.91 ENST00000304677.3
RNASE6
ribonuclease A family member k6
chr15_+_88638947 0.91 ENST00000559876.2
ISG20
interferon stimulated exonuclease gene 20
chr1_+_198639162 0.91 ENST00000418674.1
PTPRC
protein tyrosine phosphatase receptor type C
chr6_-_2841853 0.90 ENST00000380739.6
SERPINB1
serpin family B member 1
chr11_+_59713403 0.90 ENST00000641815.1
STX3
syntaxin 3
chr2_+_90172802 0.90 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr1_+_28914614 0.89 ENST00000645184.1
EPB41
erythrocyte membrane protein band 4.1
chr16_+_31033092 0.89 ENST00000394998.5
STX4
syntaxin 4
chr7_+_142544199 0.89 ENST00000611462.1
TRBV10-3
T cell receptor beta variable 10-3
chr19_-_54063905 0.89 ENST00000645936.1
ENST00000376626.5
ENST00000366170.6
ENST00000425006.3
VSTM1
V-set and transmembrane domain containing 1
chr1_-_206923183 0.89 ENST00000525793.5
FCMR
Fc fragment of IgM receptor
chr17_+_59707636 0.89 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
VMP1
vacuole membrane protein 1
chr16_+_28985043 0.88 ENST00000395456.7
ENST00000564277.5
ENST00000630764.2
ENST00000354453.7
LAT
linker for activation of T cells
chr1_+_28914597 0.88 ENST00000349460.9
EPB41
erythrocyte membrane protein band 4.1
chr2_+_218245426 0.88 ENST00000456575.1
ARPC2
actin related protein 2/3 complex subunit 2
chr17_+_44004604 0.87 ENST00000293404.8
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr7_+_142592928 0.86 ENST00000616518.1
TRBV15
T cell receptor beta variable 15
chr6_+_41053194 0.85 ENST00000244669.3
APOBEC2
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr17_+_82237134 0.85 ENST00000583025.1
SLC16A3
solute carrier family 16 member 3
chr7_+_142500027 0.85 ENST00000390375.2
TRBV5-6
T cell receptor beta variable 5-6
chr11_+_118883884 0.83 ENST00000292174.5
CXCR5
C-X-C motif chemokine receptor 5
chr2_+_201129318 0.83 ENST00000417748.1
CFLAR
CASP8 and FADD like apoptosis regulator
chr14_+_21712313 0.83 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr11_-_126268810 0.81 ENST00000332118.11
SRPRA
SRP receptor subunit alpha
chr6_-_32816910 0.80 ENST00000447394.1
ENST00000438763.7
HLA-DOB
major histocompatibility complex, class II, DO beta
chr2_+_203936755 0.80 ENST00000316386.11
ENST00000435193.1
ICOS
inducible T cell costimulator
chr7_+_142580911 0.79 ENST00000621184.1
TRBV12-5
T cell receptor beta variable 12-5
chr5_-_180815563 0.79 ENST00000513431.5
ENST00000514438.1
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr9_-_114387973 0.79 ENST00000374088.8
AKNA
AT-hook transcription factor
chr1_-_92486049 0.79 ENST00000427103.5
GFI1
growth factor independent 1 transcriptional repressor
chr19_-_43656540 0.78 ENST00000595038.5
PLAUR
plasminogen activator, urokinase receptor
chr12_-_10409757 0.78 ENST00000309384.2
KLRC4
killer cell lectin like receptor C4
chr3_-_120647018 0.77 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr19_+_41003946 0.77 ENST00000593831.1
CYP2B6
cytochrome P450 family 2 subfamily B member 6
chr13_-_99258366 0.76 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr22_+_22322452 0.76 ENST00000390290.3
IGLV1-51
immunoglobulin lambda variable 1-51
chr8_+_23528995 0.75 ENST00000523930.1
SLC25A37
solute carrier family 25 member 37
chr6_-_55875583 0.75 ENST00000370830.4
BMP5
bone morphogenetic protein 5
chr4_-_40630588 0.75 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr7_-_115968302 0.74 ENST00000457268.5
TFEC
transcription factor EC
chr14_-_22815493 0.74 ENST00000555911.1
SLC7A7
solute carrier family 7 member 7
chrX_-_78327626 0.74 ENST00000614798.1
CYSLTR1
cysteinyl leukotriene receptor 1
chr14_+_21978440 0.74 ENST00000390443.3
TRAV8-6
T cell receptor alpha variable 8-6
chr14_+_21918161 0.73 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chrX_+_124346571 0.73 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr1_+_171090892 0.73 ENST00000367755.9
ENST00000479749.1
FMO3
flavin containing dimethylaniline monoxygenase 3
chr2_-_210315160 0.73 ENST00000352451.4
MYL1
myosin light chain 1
chr1_-_146021724 0.73 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
HJV
hemojuvelin BMP co-receptor
chr15_+_81296913 0.72 ENST00000394652.6
IL16
interleukin 16
chr16_+_21612637 0.72 ENST00000568826.1
METTL9
methyltransferase like 9
chr17_-_7252456 0.72 ENST00000571409.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr9_-_92482461 0.71 ENST00000651738.1
ASPN
asporin
chr21_+_29300111 0.71 ENST00000451655.5
BACH1
BTB domain and CNC homolog 1
chr17_-_7252054 0.71 ENST00000575783.5
ENST00000573600.5
CTDNEP1
CTD nuclear envelope phosphatase 1
chr2_-_160200251 0.71 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
ITGB6
integrin subunit beta 6
chr7_+_142554828 0.70 ENST00000611787.1
TRBV11-3
T cell receptor beta variable 11-3
chr4_-_122621011 0.69 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr21_-_14546351 0.68 ENST00000619120.4
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_-_48114523 0.68 ENST00000506073.1
TXK
TXK tyrosine kinase
chr14_+_51847145 0.67 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr16_+_28984795 0.67 ENST00000395461.7
LAT
linker for activation of T cells
chr17_-_40799939 0.67 ENST00000306658.8
KRT28
keratin 28
chr11_-_26572102 0.65 ENST00000455601.6
MUC15
mucin 15, cell surface associated
chr3_-_155293665 0.65 ENST00000489090.2
STRIT1
small transmembrane regulator of ion transport 1
chr12_+_20810698 0.65 ENST00000540853.5
ENST00000381545.8
SLCO1B3
solute carrier organic anion transporter family member 1B3
chr9_-_35619542 0.65 ENST00000396757.6
CD72
CD72 molecule
chr10_-_6062290 0.65 ENST00000256876.10
ENST00000379954.5
IL2RA
interleukin 2 receptor subunit alpha
chr3_-_52454032 0.65 ENST00000232975.8
TNNC1
troponin C1, slow skeletal and cardiac type
chr5_-_95081858 0.64 ENST00000505465.1
MCTP1
multiple C2 and transmembrane domain containing 1
chr1_-_222712428 0.64 ENST00000355727.3
ENST00000340020.11
AIDA
axin interactor, dorsalization associated
chr2_+_37342816 0.63 ENST00000650442.1
QPCT
glutaminyl-peptide cyclotransferase
chr1_+_206440061 0.63 ENST00000604925.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_6619353 0.63 ENST00000642892.1
ENST00000645620.1
ENST00000533371.6
ENST00000647152.1
ENST00000644810.1
ENST00000299427.12
ENST00000682424.1
ENST00000644218.1
ENST00000528657.2
ENST00000531754.2
TPP1
tripeptidyl peptidase 1
chr1_+_117001744 0.63 ENST00000256652.8
ENST00000682167.1
ENST00000369470.1
CD101
CD101 molecule
chr6_+_63211446 0.63 ENST00000370659.1
FKBP1C
FKBP prolyl isomerase family member 1C
chr3_-_58210961 0.62 ENST00000486455.5
ENST00000394549.7
DNASE1L3
deoxyribonuclease 1 like 3
chr20_+_45363454 0.62 ENST00000453003.1
SYS1
SYS1 golgi trafficking protein
chr5_-_180815528 0.62 ENST00000333055.8
MGAT1
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr19_-_54063882 0.61 ENST00000338372.7
VSTM1
V-set and transmembrane domain containing 1
chr1_-_209802149 0.61 ENST00000456314.1
IRF6
interferon regulatory factor 6
chr1_-_56966006 0.61 ENST00000371237.9
C8B
complement C8 beta chain
chr12_+_51239278 0.61 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr12_-_52814106 0.60 ENST00000551956.2
KRT4
keratin 4
chr4_-_40630826 0.60 ENST00000505414.5
ENST00000511598.5
RBM47
RNA binding motif protein 47
chr11_-_126268913 0.60 ENST00000532259.1
SRPRA
SRP receptor subunit alpha
chr3_-_146528750 0.59 ENST00000483300.5
PLSCR1
phospholipid scramblase 1
chr2_-_160200310 0.59 ENST00000620391.4
ITGB6
integrin subunit beta 6
chr16_+_3018390 0.59 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr3_-_12664101 0.59 ENST00000251849.9
ENST00000442415.7
RAF1
Raf-1 proto-oncogene, serine/threonine kinase
chr3_+_16265160 0.58 ENST00000627468.2
ENST00000605932.5
ENST00000435829.6
ENST00000285083.10
OXNAD1
oxidoreductase NAD binding domain containing 1
chr3_-_27484335 0.58 ENST00000454389.5
ENST00000440156.5
ENST00000437179.5
ENST00000446700.5
ENST00000455077.5
SLC4A7
solute carrier family 4 member 7
chr8_-_123653794 0.58 ENST00000684634.1
KLHL38
kelch like family member 38
chr3_-_27484374 0.58 ENST00000445684.5
ENST00000425128.6
SLC4A7
solute carrier family 4 member 7
chr1_-_99766620 0.57 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr1_-_157841800 0.57 ENST00000368174.5
CD5L
CD5 molecule like
chr9_-_114388020 0.57 ENST00000312033.3
AKNA
AT-hook transcription factor
chr8_+_127735511 0.57 ENST00000517291.2
MYC
MYC proto-oncogene, bHLH transcription factor
chr12_-_102481744 0.56 ENST00000644491.1
IGF1
insulin like growth factor 1
chr4_-_40630739 0.56 ENST00000511902.5
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr10_-_72088504 0.56 ENST00000536168.2
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr2_+_161231078 0.56 ENST00000439442.1
TANK
TRAF family member associated NFKB activator
chr14_+_24310134 0.56 ENST00000533293.2
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr19_+_43596480 0.56 ENST00000533118.5
ZNF576
zinc finger protein 576
chr11_-_26572130 0.56 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr17_+_7252237 0.55 ENST00000570500.5
ELP5
elongator acetyltransferase complex subunit 5
chr8_+_75539893 0.55 ENST00000674002.1
HNF4G
hepatocyte nuclear factor 4 gamma
chr5_+_134371561 0.55 ENST00000265339.7
ENST00000506787.5
ENST00000507277.1
UBE2B
ubiquitin conjugating enzyme E2 B
chr4_+_70518563 0.54 ENST00000339336.9
AMTN
amelotin
chr15_+_80072559 0.54 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
ZFAND6
zinc finger AN1-type containing 6
chr13_+_48256214 0.54 ENST00000650237.1
ITM2B
integral membrane protein 2B
chr1_-_154206327 0.54 ENST00000368525.4
C1orf189
chromosome 1 open reading frame 189
chr5_-_150086511 0.54 ENST00000675795.1
CSF1R
colony stimulating factor 1 receptor
chrX_-_30577759 0.54 ENST00000378962.4
TASL
TLR adaptor interacting with endolysosomal SLC15A4
chr7_+_142645938 0.54 ENST00000390396.1
TRBV23-1
T cell receptor beta variable 23-1 (non-functional)
chr7_+_142399860 0.53 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1
chr10_+_35195843 0.53 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.7 4.0 GO:0071461 cellular response to redox state(GO:0071461)
0.6 3.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.6 7.8 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.6 2.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 1.7 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.5 7.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.5 2.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 1.5 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.4 0.4 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 1.7 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 0.8 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.9 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.3 0.8 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.3 0.8 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.3 1.0 GO:0044145 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 2.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 0.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.2 1.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.7 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.2 2.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.2 2.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.3 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.2 1.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 1.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 1.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.4 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 1.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 1.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 2.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.2 GO:0001777 T cell homeostatic proliferation(GO:0001777)
0.2 1.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 1.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 2.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 0.6 GO:0002086 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.2 1.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.9 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.2 4.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.2 1.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.7 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.4 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.5 GO:0060903 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.4 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758)
0.1 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 1.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.9 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 1.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 0.7 GO:0045007 depurination(GO:0045007)
0.1 0.9 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.3 GO:0060279 negative regulation of B cell differentiation(GO:0045578) positive regulation of ovulation(GO:0060279)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.3 GO:1904882 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.5 GO:1903758 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.4 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 3.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 1.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 2.3 GO:0045730 respiratory burst(GO:0045730)
0.1 0.8 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.2 GO:0060003 copper ion export(GO:0060003)
0.0 0.6 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.0 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.8 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 1.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 1.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.5 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.9 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.5 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.4 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.3 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 1.5 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.7 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 1.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.8 GO:0048535 lymph node development(GO:0048535)
0.0 1.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.0 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 1.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) mammary duct terminal end bud growth(GO:0060763)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) DNA 3' dephosphorylation(GO:0098503) DNA 3' dephosphorylation involved in DNA repair(GO:0098504) polynucleotide 3' dephosphorylation(GO:0098506)
0.0 2.3 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.1 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 2.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.2 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 2.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 3.4 GO:0070268 cornification(GO:0070268)
0.0 3.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0051659 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) maintenance of mitochondrion location(GO:0051659)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 1.1 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.4 GO:0071402 cellular response to lipoprotein particle stimulus(GO:0071402)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 1.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:2000870 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 2.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.9 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.4 GO:0048087 positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 2.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.7 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.1 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0060046 fusion of sperm to egg plasma membrane(GO:0007342) regulation of acrosome reaction(GO:0060046)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4 1.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 1.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 1.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 2.3 GO:0032010 phagolysosome(GO:0032010)
0.2 1.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 0.5 GO:0002141 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.2 7.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.9 GO:0071438 invadopodium membrane(GO:0071438)
0.1 2.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.3 GO:0042588 zymogen granule(GO:0042588)
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 5.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 4.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.8 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 3.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 2.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 3.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 7.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 2.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.4 4.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 1.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.9 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 2.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 0.8 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.2 3.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.7 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 0.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 1.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.7 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 8.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 2.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.5 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 2.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.3 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 3.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 1.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 1.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 3.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.2 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 2.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 4.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.0 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 5.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 1.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 2.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 2.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.0 GO:0005549 odorant binding(GO:0005549)
0.0 2.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 3.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 10.3 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 2.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.3 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 1.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 3.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.7 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 2.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 4.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.4 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 2.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 5.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation