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Illumina Body Map 2 (GSE30611)

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Results for NFIA

Z-value: 1.54

Motif logo

Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
ENSG00000162599.17 nuclear factor I A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg38_v1_chr1_+_61081728_610818620.327.6e-02Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_10518536 13.10 ENST00000226207.6
myosin heavy chain 1
chr17_-_10549612 6.51 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr17_-_10549652 6.17 ENST00000245503.10
myosin heavy chain 2
chr1_-_26067622 5.85 ENST00000374272.4
tripartite motif containing 63
chr11_+_78063851 5.49 ENST00000281030.2
thyroid hormone responsive
chr1_-_146021724 5.42 ENST00000475797.1
ENST00000497365.5
ENST00000336751.11
ENST00000634927.1
ENST00000421822.2
hemojuvelin BMP co-receptor
chr3_-_155293665 5.30 ENST00000489090.2
small transmembrane regulator of ion transport 1
chr10_+_24239181 4.92 ENST00000438429.5
KIAA1217
chr17_-_10549694 4.33 ENST00000622564.4
myosin heavy chain 2
chr13_+_23180960 3.26 ENST00000218867.4
sarcoglycan gamma
chr20_+_31819302 3.18 ENST00000375994.6
myosin light chain kinase 2
chr20_+_31819348 3.16 ENST00000375985.5
myosin light chain kinase 2
chr1_+_160190567 3.06 ENST00000368078.8
calsequestrin 1
chr16_+_30372291 3.06 ENST00000568749.5
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_+_114323098 3.06 ENST00000259396.9
orosomucoid 1
chr12_+_57434778 2.96 ENST00000309668.3
inhibin subunit beta C
chr4_-_44651619 2.88 ENST00000415895.9
ENST00000332990.6
Yip1 domain family member 7
chr10_+_5196831 2.82 ENST00000263126.3
aldo-keto reductase family 1 member C4
chr10_+_24466487 2.51 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr6_-_123636979 2.50 ENST00000662930.1
triadin
chr8_+_66432475 2.46 ENST00000415254.5
ENST00000396623.8
alcohol dehydrogenase iron containing 1
chr3_-_52826834 2.44 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chrX_+_106201724 2.28 ENST00000372552.1
PWWP domain containing 3B
chrX_+_136169891 2.27 ENST00000449474.5
four and a half LIM domains 1
chr12_-_110920568 2.26 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chrX_+_136169833 2.25 ENST00000628032.2
four and a half LIM domains 1
chr11_-_13496018 2.22 ENST00000529816.1
parathyroid hormone
chr10_+_113553039 2.19 ENST00000351270.4
hyaluronan binding protein 2
chr1_-_201112420 2.18 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr11_-_13495984 2.18 ENST00000282091.6
parathyroid hormone
chrX_+_136169624 2.18 ENST00000394153.6
four and a half LIM domains 1
chr4_+_73404255 2.17 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr10_+_100347225 2.15 ENST00000370355.3
stearoyl-CoA desaturase
chr16_+_55324191 2.15 ENST00000290552.8
iroquois homeobox 6
chr4_-_110636963 2.15 ENST00000394595.8
paired like homeodomain 2
chr16_+_82056423 2.12 ENST00000568090.5
hydroxysteroid 17-beta dehydrogenase 2
chrX_+_136169664 2.09 ENST00000456445.5
four and a half LIM domains 1
chr6_-_123636997 2.09 ENST00000546248.5
triadin
chr6_-_123636923 2.07 ENST00000334268.9
triadin
chr17_-_10469558 2.06 ENST00000255381.2
myosin heavy chain 4
chr5_-_151347552 2.04 ENST00000335244.9
ENST00000521967.1
solute carrier family 36 member 2
chr10_+_4963406 2.01 ENST00000380872.9
ENST00000442997.5
aldo-keto reductase family 1 member C1
chr12_+_55720367 2.00 ENST00000547072.5
ENST00000552930.5
ENST00000257895.10
retinol dehydrogenase 5
chr10_+_133527355 1.95 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr8_+_96493803 1.95 ENST00000518385.5
ENST00000302190.9
syndecan 2
chr3_-_69122588 1.94 ENST00000420581.7
ENST00000489031.5
leiomodin 3
chr1_+_201190786 1.88 ENST00000335211.9
ENST00000295591.12
immunoglobulin like and fibronectin type III domain containing 1
chrX_-_15314543 1.87 ENST00000344384.8
ankyrin repeat and SOCS box containing 11
chr19_-_49155130 1.83 ENST00000595625.1
histidine rich calcium binding protein
chr16_-_55833186 1.82 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr1_-_201112451 1.82 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr4_+_39406917 1.79 ENST00000257408.5
klotho beta
chr11_-_16356538 1.78 ENST00000683767.1
SRY-box transcription factor 6
chr12_+_55720405 1.77 ENST00000548082.1
retinol dehydrogenase 5
chr1_-_203175783 1.77 ENST00000621380.1
ENST00000255416.9
myosin binding protein H
chr5_+_42423433 1.76 ENST00000230882.9
growth hormone receptor
chr18_+_31591869 1.72 ENST00000237014.8
transthyretin
chr2_+_173090598 1.71 ENST00000422149.1
mitogen-activated protein kinase kinase kinase 20
chr11_+_10305065 1.70 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr19_-_49155384 1.70 ENST00000252825.9
histidine rich calcium binding protein
chr16_-_10559135 1.69 ENST00000536829.1
epithelial membrane protein 2
chr11_-_2137277 1.69 ENST00000381392.5
ENST00000381395.5
ENST00000418738.2
insulin like growth factor 2
chr19_-_39833615 1.65 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr3_+_184315131 1.62 ENST00000427845.5
ENST00000342981.8
eukaryotic translation initiation factor 4 gamma 1
chr4_+_41360759 1.62 ENST00000508501.5
ENST00000512946.5
ENST00000313860.11
ENST00000512632.5
ENST00000512820.5
LIM and calponin homology domains 1
chr4_-_53652453 1.58 ENST00000507168.5
ENST00000510143.1
ligand of numb-protein X 1
chr12_-_69699285 1.58 ENST00000553096.5
ENST00000330891.10
bestrophin 3
chr2_-_31414694 1.58 ENST00000379416.4
xanthine dehydrogenase
chr7_-_44325421 1.55 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr9_-_34589701 1.54 ENST00000351266.8
ciliary neurotrophic factor receptor
chr17_-_15265230 1.54 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
peripheral myelin protein 22
chr1_-_13513988 1.54 ENST00000376085.4
leucine rich repeat containing 38
chr9_-_34590123 1.53 ENST00000417345.2
ENST00000610543.4
ciliary neurotrophic factor receptor
chr6_+_122779707 1.51 ENST00000368444.8
ENST00000356535.4
fatty acid binding protein 7
chr8_+_40153475 1.49 ENST00000315792.5
transcriptional and immune response regulator
chr9_-_34589716 1.48 ENST00000378980.8
ciliary neurotrophic factor receptor
chr13_-_35476682 1.45 ENST00000379919.6
mab-21 like 1
chr3_+_184315347 1.45 ENST00000424196.5
eukaryotic translation initiation factor 4 gamma 1
chr9_-_127122623 1.43 ENST00000373417.1
ENST00000373425.8
angiopoietin like 2
chr16_+_6483728 1.42 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr6_-_123636906 1.41 ENST00000628709.2
triadin
chr12_-_52517929 1.39 ENST00000548409.5
keratin 5
chr7_+_95485934 1.37 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr3_+_119294337 1.36 ENST00000264245.9
Rho GTPase activating protein 31
chr15_+_86079863 1.36 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr12_-_46832370 1.36 ENST00000546940.1
solute carrier family 38 member 4
chr9_-_19149278 1.35 ENST00000434144.5
perilipin 2
chr1_+_67685342 1.34 ENST00000617962.2
growth arrest and DNA damage inducible alpha
chr12_-_48999363 1.34 ENST00000421952.3
dendrin
chr10_+_72893734 1.34 ENST00000334011.10
oncoprotein induced transcript 3
chr3_+_148791058 1.33 ENST00000491148.5
carboxypeptidase B1
chr8_-_42501224 1.32 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr8_+_132919403 1.32 ENST00000519178.5
thyroglobulin
chr4_+_94489030 1.31 ENST00000510099.5
PDZ and LIM domain 5
chr1_-_209618766 1.30 ENST00000455193.1
laminin subunit beta 3
chr1_+_67685170 1.29 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr10_-_80289647 1.28 ENST00000372213.8
methionine adenosyltransferase 1A
chr5_+_54455661 1.27 ENST00000302005.3
heat shock protein family B (small) member 3
chr1_-_114670018 1.26 ENST00000393274.6
ENST00000393276.7
DENN domain containing 2C
chr20_+_44714835 1.26 ENST00000372868.6
cellular communication network factor 5
chr12_+_110280602 1.23 ENST00000552636.2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr8_-_17895487 1.23 ENST00000427924.5
ENST00000381841.4
fibrinogen like 1
chr1_+_209704836 1.23 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chr3_+_16174628 1.23 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr3_+_148730100 1.22 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr11_-_2149603 1.22 ENST00000643349.1
novel protein
chr5_+_36606355 1.21 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr11_-_61580826 1.20 ENST00000540677.5
ENST00000542836.5
ENST00000542670.5
ENST00000535826.5
ENST00000545053.1
ENST00000539008.6
synaptotagmin 7
chr20_+_44714853 1.17 ENST00000372865.4
cellular communication network factor 5
chr5_-_180591488 1.16 ENST00000292641.4
secretoglobin family 3A member 1
chr11_+_111602380 1.16 ENST00000304987.4
salt inducible kinase 2
chr1_+_15659869 1.16 ENST00000345034.1
regulator of solute carriers 1
chr18_+_63476927 1.15 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr3_-_194351290 1.15 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr6_+_63571702 1.15 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr16_+_6483813 1.15 ENST00000675653.1
RNA binding fox-1 homolog 1
chr19_+_41003946 1.14 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr9_+_470291 1.13 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr2_+_233681877 1.12 ENST00000373426.4
UDP glucuronosyltransferase family 1 member A7
chr12_-_110920710 1.10 ENST00000546404.1
myosin light chain 2
chr1_-_151805419 1.10 ENST00000368820.4
leucine rich repeat and Ig domain containing 4
chr10_-_102837406 1.10 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr15_+_62758585 1.08 ENST00000472902.1
talin 2
chr12_-_52520371 1.07 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr19_-_39834127 1.07 ENST00000601972.1
ENST00000430012.6
ENST00000323039.10
ENST00000348817.7
dual specificity tyrosine phosphorylation regulated kinase 1B
chr6_-_75363003 1.06 ENST00000370020.1
filamin A interacting protein 1
chr10_+_72893572 1.06 ENST00000622652.1
oncoprotein induced transcript 3
chr11_-_64245816 1.06 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr7_-_56092932 1.05 ENST00000446428.5
ENST00000432123.5
ENST00000297373.7
phosphorylase kinase catalytic subunit gamma 1
chr16_+_58249910 1.05 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr10_+_5048748 1.05 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr5_+_43602648 1.05 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr16_-_69356306 1.04 ENST00000563634.1
novel protein
chr21_-_30216047 1.04 ENST00000399899.2
claudin 8
chr6_-_123636966 1.04 ENST00000542443.5
triadin
chr17_-_64230727 1.03 ENST00000583097.5
ENST00000615733.4
testis expressed 2
chr2_+_134838610 1.03 ENST00000356140.10
ENST00000392928.5
aminocarboxymuconate semialdehyde decarboxylase
chr2_-_227714589 1.03 ENST00000258403.8
solute carrier family 19 member 3
chr7_-_44325490 1.02 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr8_+_96584920 1.02 ENST00000521590.5
syndecan 2
chr4_-_100190782 1.02 ENST00000513992.1
DNA damage inducible transcript 4 like
chrX_+_22032427 1.00 ENST00000684143.1
phosphate regulating endopeptidase homolog X-linked
chr14_-_74612021 1.00 ENST00000556690.5
latent transforming growth factor beta binding protein 2
chr15_+_67166019 1.00 ENST00000537194.6
SMAD family member 3
chr19_-_42442938 1.00 ENST00000601181.6
C-X-C motif chemokine ligand 17
chr11_-_61333784 0.98 ENST00000680367.1
ENST00000681803.1
damage specific DNA binding protein 1
chr17_-_41612757 0.98 ENST00000301653.9
ENST00000593067.1
keratin 16
chr17_-_55732074 0.98 ENST00000575734.5
transmembrane protein 100
chr11_-_26572254 0.97 ENST00000529533.6
mucin 15, cell surface associated
chr8_-_120811988 0.97 ENST00000517992.2
syntrophin beta 1
chrX_+_13569593 0.96 ENST00000361306.6
ENST00000380602.3
EGF like domain multiple 6
chr2_+_233636445 0.95 ENST00000344644.9
UDP glucuronosyltransferase family 1 member A10
chr11_-_113773668 0.94 ENST00000200135.8
zw10 kinetochore protein
chr7_-_56092974 0.94 ENST00000452681.6
ENST00000537360.5
phosphorylase kinase catalytic subunit gamma 1
chr19_+_41219235 0.93 ENST00000359092.7
AXL receptor tyrosine kinase
chr1_+_170663134 0.93 ENST00000367760.7
paired related homeobox 1
chr17_+_70104848 0.93 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chr10_-_99430617 0.92 ENST00000370508.7
glutamic-oxaloacetic transaminase 1
chr11_+_27041313 0.92 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr3_+_184315763 0.92 ENST00000456033.5
eukaryotic translation initiation factor 4 gamma 1
chr2_+_233636502 0.92 ENST00000373445.1
UDP glucuronosyltransferase family 1 member A10
chr20_+_6767678 0.90 ENST00000378827.5
bone morphogenetic protein 2
chr7_-_99735093 0.89 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr18_+_61333424 0.88 ENST00000262717.9
cadherin 20
chr13_-_28495079 0.88 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
fms related receptor tyrosine kinase 1
chr1_+_207104226 0.88 ENST00000367070.8
complement component 4 binding protein alpha
chr12_-_69699331 0.87 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr3_-_15797930 0.87 ENST00000683139.1
ankyrin repeat domain 28
chr2_+_26244894 0.87 ENST00000405867.7
ENST00000317799.10
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr22_+_44031345 0.87 ENST00000444029.5
parvin beta
chr2_-_110534010 0.87 ENST00000437167.1
RANBP2 like and GRIP domain containing 6
chr4_-_186596770 0.86 ENST00000512772.5
FAT atypical cadherin 1
chr12_-_69699353 0.86 ENST00000331471.8
bestrophin 3
chr14_-_74612226 0.86 ENST00000261978.9
latent transforming growth factor beta binding protein 2
chr3_+_69763549 0.85 ENST00000472437.5
melanocyte inducing transcription factor
chr19_+_41219177 0.84 ENST00000301178.9
AXL receptor tyrosine kinase
chr2_+_188974364 0.83 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr4_+_186227501 0.83 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chrX_-_30889394 0.82 ENST00000288422.3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3
chr12_+_52056514 0.82 ENST00000550582.2
nuclear receptor subfamily 4 group A member 1
chr1_+_45913583 0.81 ENST00000372008.6
microtubule associated serine/threonine kinase 2
chr6_+_30983710 0.81 ENST00000486149.2
ENST00000376296.3
mucin 21, cell surface associated
chr11_+_10305370 0.81 ENST00000528544.1
adrenomedullin
chr3_+_51977833 0.81 ENST00000637978.1
ABHD14A-ACY1 readthrough
chr12_+_7062583 0.81 ENST00000542978.1
complement C1s
chr3_+_189171948 0.80 ENST00000345063.8
tumor protein p63 regulated 1
chr1_+_61081728 0.80 ENST00000371189.8
nuclear factor I A
chrX_+_131083706 0.79 ENST00000370921.1
Rho GTPase activating protein 36
chr14_+_91114667 0.79 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr1_+_207104287 0.79 ENST00000421786.5
complement component 4 binding protein alpha
chr10_+_102776237 0.79 ENST00000369889.5
WW domain binding protein 1 like
chr9_+_128149447 0.78 ENST00000277480.7
ENST00000372998.1
lipocalin 2
chr2_+_26244731 0.78 ENST00000537713.5
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr3_-_47892743 0.78 ENST00000420772.6
microtubule associated protein 4
chr11_-_26572102 0.77 ENST00000455601.6
mucin 15, cell surface associated
chr2_-_162243375 0.77 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr2_-_241271943 0.76 ENST00000444092.5
high density lipoprotein binding protein
chr1_-_160284205 0.76 ENST00000392220.2
peroxisomal biogenesis factor 19
chr20_+_33007695 0.76 ENST00000170150.4
BPI fold containing family B member 2
chr12_-_69699382 0.75 ENST00000551160.5
bestrophin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
1.2 3.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
1.0 5.9 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.0 5.9 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.0 18.2 GO:0001778 plasma membrane repair(GO:0001778)
0.9 1.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.9 6.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.9 4.4 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.8 2.5 GO:0015993 molecular hydrogen transport(GO:0015993)
0.7 2.2 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.7 2.1 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.6 3.5 GO:0051552 flavone metabolic process(GO:0051552)
0.5 1.6 GO:0046110 xanthine metabolic process(GO:0046110)
0.5 3.0 GO:0008218 bioluminescence(GO:0008218)
0.4 1.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.4 1.2 GO:1904640 response to methionine(GO:1904640)
0.4 2.0 GO:0010193 response to ozone(GO:0010193)
0.4 4.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.4 2.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.4 2.5 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.3 1.0 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.3 1.0 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.3 1.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 2.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.3 0.9 GO:0006532 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.3 1.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 0.9 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.3 1.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.3 0.9 GO:0036323 vascular endothelial growth factor receptor-1 signaling pathway(GO:0036323)
0.3 1.4 GO:1904383 response to sodium phosphate(GO:1904383)
0.3 1.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.7 GO:0006740 NADPH regeneration(GO:0006740)
0.3 4.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.3 1.8 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.2 0.7 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 0.7 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.2 2.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 1.4 GO:0097325 melanocyte proliferation(GO:0097325)
0.2 3.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.2 0.8 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.2 1.0 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 1.2 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868)
0.2 1.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 1.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 3.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.6 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.2 1.7 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 1.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 1.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 1.4 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.7 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2 2.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.2 4.2 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.2 0.8 GO:0001757 somite specification(GO:0001757)
0.2 0.5 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.2 1.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 5.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 0.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 0.8 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 1.1 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.4 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 1.6 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.5 GO:2000196 positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 1.4 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.9 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.4 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.3 GO:0003032 detection of oxygen(GO:0003032)
0.1 1.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 4.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.1 1.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.7 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.5 GO:0060174 limb bud formation(GO:0060174)
0.1 0.3 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 2.8 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.5 GO:0061056 sclerotome development(GO:0061056)
0.1 1.3 GO:0015705 iodide transport(GO:0015705)
0.1 0.7 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 2.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 3.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.3 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 0.7 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.7 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 1.5 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 9.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.5 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.5 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.4 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.1 1.5 GO:0032060 bleb assembly(GO:0032060)
0.1 1.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.8 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.4 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.3 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 3.5 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0098923 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 0.4 GO:0033504 floor plate development(GO:0033504)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.9 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 1.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 1.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.7 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 2.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 2.0 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.4 GO:0072553 terminal button organization(GO:0072553)
0.0 1.0 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.7 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.0 2.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.7 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 2.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 7.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.8 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.7 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 1.0 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 1.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 2.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 3.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 1.7 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 1.3 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 1.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.7 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 2.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.8 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.6 GO:0010039 response to iron ion(GO:0010039)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0038016 insulin receptor internalization(GO:0038016)
0.0 0.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.7 GO:0055001 muscle cell development(GO:0055001)
0.0 8.2 GO:0006936 muscle contraction(GO:0006936)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.6 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 1.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.1 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 1.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826) interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.7 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 17.0 GO:0005826 actomyosin contractile ring(GO:0005826)
1.1 15.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.9 4.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.7 17.8 GO:0032982 myosin filament(GO:0032982)
0.6 1.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 3.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 0.9 GO:0070939 Dsl1p complex(GO:0070939)
0.2 3.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 3.1 GO:0005859 muscle myosin complex(GO:0005859)
0.2 3.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.6 GO:0005602 complement component C1 complex(GO:0005602)
0.1 1.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.3 GO:0005610 laminin-5 complex(GO:0005610)
0.1 3.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 7.1 GO:0031430 M band(GO:0031430)
0.1 1.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.9 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.5 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 1.1 GO:0032009 early phagosome(GO:0032009)
0.1 0.2 GO:0036457 keratohyalin granule(GO:0036457)
0.1 1.2 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 1.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.4 GO:0044308 axonal spine(GO:0044308)
0.1 1.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:1990696 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 4.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.2 GO:0033643 host cell part(GO:0033643)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 6.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 2.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 4.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 1.5 GO:0043218 compact myelin(GO:0043218)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 1.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 2.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.8 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 6.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.7 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.6 1.9 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.6 5.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 1.7 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.5 2.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.5 2.8 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 4.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 1.2 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.4 1.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.4 1.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.4 20.4 GO:0000146 microfilament motor activity(GO:0000146)
0.4 1.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 1.9 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 2.5 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.3 0.9 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 2.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 0.9 GO:0036327 VEGF-A-activated receptor activity(GO:0036326) VEGF-B-activated receptor activity(GO:0036327) placental growth factor-activated receptor activity(GO:0036332)
0.3 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.3 1.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.3 4.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.7 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 5.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 5.9 GO:0031432 titin binding(GO:0031432)
0.2 2.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 2.0 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.2 0.6 GO:0030305 heparanase activity(GO:0030305)
0.2 2.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 1.4 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.6 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.1 3.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.4 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 2.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 4.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.8 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 4.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 4.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.5 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 0.9 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0032190 acrosin binding(GO:0032190)
0.1 3.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 2.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 2.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 12.1 GO:0003774 motor activity(GO:0003774)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.8 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0004615 phosphomannomutase activity(GO:0004615)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.3 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 8.0 GO:0005179 hormone activity(GO:0005179)
0.1 2.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 1.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 4.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.0 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 11.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 2.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 2.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) aromatase activity(GO:0070330)
0.0 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 2.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 2.1 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 1.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 23.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 6.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 5.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 PID BMP PATHWAY BMP receptor signaling
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 4.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.9 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 4.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 3.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 3.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 10.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 3.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors