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Illumina Body Map 2 (GSE30611)

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Results for NFKB1

Z-value: 1.53

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
ENSG00000109320.13 nuclear factor kappa B subunit 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg38_v1_chr4_+_102501298_1025014740.105.9e-01Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_70188967 4.57 ENST00000381269.6
ENST00000357887.7
solute carrier family 8 member A3
chr6_-_31582415 3.80 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr14_-_70188937 3.70 ENST00000356921.7
solute carrier family 8 member A3
chr17_-_63699162 3.47 ENST00000582055.1
LIM domain containing 2
chr16_+_7303245 3.27 ENST00000674626.1
RNA binding fox-1 homolog 1
chr22_-_37244237 3.18 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr12_-_54981838 3.11 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr16_+_50696999 3.10 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr19_+_50418930 3.08 ENST00000439922.6
ENST00000595883.6
ENST00000597855.5
ENST00000596074.5
ENST00000594685.1
ENST00000270632.7
Spi-B transcription factor
chr19_+_45001430 3.04 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr19_+_17527250 2.99 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr17_-_63699730 2.96 ENST00000578061.5
LIM domain containing 2
chr5_+_10564064 2.82 ENST00000296657.7
ankyrin repeat domain 33B
chr14_-_50831046 2.80 ENST00000476352.5
ENST00000324330.13
ENST00000382041.7
ENST00000453401.6
ENST00000530997.7
ninein
chr22_-_37244417 2.78 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr3_-_112133218 2.67 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr7_+_143316105 2.64 ENST00000343257.7
ENST00000650516.1
chloride voltage-gated channel 1
chr19_+_41877267 2.57 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr11_+_102317492 2.57 ENST00000673846.1
baculoviral IAP repeat containing 3
chr14_+_22086401 2.56 ENST00000390451.2
T cell receptor alpha variable 23/delta variable 6
chr16_+_50742037 2.55 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr16_+_50742110 2.54 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr6_+_32637396 2.47 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr4_-_8158689 2.47 ENST00000505872.5
ENST00000341937.9
ENST00000361581.9
ENST00000407564.7
ENST00000361737.9
ENST00000447017.7
ENST00000428004.6
actin binding LIM protein family member 2
chr16_+_50742059 2.42 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr16_+_6019585 2.42 ENST00000547372.5
RNA binding fox-1 homolog 1
chr6_+_31572279 2.41 ENST00000418386.3
lymphotoxin alpha
chr5_+_35852695 2.27 ENST00000508941.5
interleukin 7 receptor
chr11_+_118883884 2.26 ENST00000292174.5
C-X-C motif chemokine receptor 5
chr22_+_36922040 2.23 ENST00000406230.5
colony stimulating factor 2 receptor subunit beta
chr14_+_32329341 2.22 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr19_+_17527232 2.19 ENST00000601861.5
niban apoptosis regulator 3
chr14_-_50830641 2.18 ENST00000453196.6
ENST00000496749.1
ninein
chr15_+_85380672 2.18 ENST00000361243.6
ENST00000560256.1
A-kinase anchoring protein 13
chr17_-_1628808 2.09 ENST00000301335.10
solute carrier family 43 member 2
chr11_+_102317450 2.09 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr4_-_184474037 2.07 ENST00000510814.5
ENST00000507523.5
ENST00000506230.5
interferon regulatory factor 2
chr14_-_50830479 2.07 ENST00000382043.8
ninein
chr15_+_85380565 2.04 ENST00000559362.5
ENST00000394518.7
A-kinase anchoring protein 13
chr20_-_51542658 2.03 ENST00000396009.7
ENST00000371564.8
ENST00000610033.5
nuclear factor of activated T cells 2
chr12_-_57738740 2.03 ENST00000547588.6
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_+_32329256 2.00 ENST00000280979.9
A-kinase anchoring protein 6
chr10_+_102394488 2.00 ENST00000369966.8
nuclear factor kappa B subunit 2
chr19_+_1067493 1.97 ENST00000586866.5
Rho GTPase activating protein 45
chr9_+_79572572 1.95 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chrX_-_21658324 1.95 ENST00000379499.3
kelch like family member 34
chr22_-_38755990 1.93 ENST00000405018.5
ENST00000438058.5
Sad1 and UNC84 domain containing 2
chr1_-_202159977 1.93 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr16_+_6019016 1.92 ENST00000550418.6
RNA binding fox-1 homolog 1
chr19_+_1067144 1.90 ENST00000313093.7
Rho GTPase activating protein 45
chr19_+_1067272 1.89 ENST00000590214.5
Rho GTPase activating protein 45
chr6_+_32637419 1.88 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr19_-_39833615 1.87 ENST00000593685.5
ENST00000600611.5
dual specificity tyrosine phosphorylation regulated kinase 1B
chr11_+_102317542 1.87 ENST00000532808.5
baculoviral IAP repeat containing 3
chr14_+_22105305 1.84 ENST00000390453.1
T cell receptor alpha variable 24
chr6_-_142946312 1.83 ENST00000367604.6
HIVEP zinc finger 2
chr9_-_133479075 1.83 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr11_-_77474041 1.82 ENST00000278568.8
p21 (RAC1) activated kinase 1
chr6_+_106086316 1.82 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr16_+_6019071 1.79 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr2_+_218880844 1.78 ENST00000258411.8
Wnt family member 10A
chr11_-_77474087 1.78 ENST00000356341.8
p21 (RAC1) activated kinase 1
chr14_+_75522531 1.77 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr1_-_202160577 1.77 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
protein tyrosine phosphatase non-receptor type 7
chr19_-_6591103 1.76 ENST00000423145.7
ENST00000245903.4
CD70 molecule
chr11_+_122655712 1.76 ENST00000284273.6
ubiquitin associated and SH3 domain containing B
chr1_-_202161575 1.73 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
protein tyrosine phosphatase non-receptor type 7
chr19_-_4831689 1.71 ENST00000248244.6
toll like receptor adaptor molecule 1
chr19_-_51417619 1.71 ENST00000441969.7
ENST00000339313.10
ENST00000525998.5
ENST00000436984.6
sialic acid binding Ig like lectin 10
chrX_-_30577759 1.70 ENST00000378962.4
TLR adaptor interacting with endolysosomal SLC15A4
chr6_+_117265550 1.69 ENST00000352536.7
ENST00000326274.6
vestigial like family member 2
chr4_-_184474518 1.68 ENST00000393593.8
interferon regulatory factor 2
chr12_+_48105466 1.68 ENST00000549003.5
ENST00000550924.6
phosphofructokinase, muscle
chr22_-_38755458 1.67 ENST00000405510.5
ENST00000433561.5
Sad1 and UNC84 domain containing 2
chr19_+_35449584 1.67 ENST00000246549.2
free fatty acid receptor 2
chr17_+_42567072 1.66 ENST00000246912.8
ENST00000346833.8
ENST00000591024.1
MAX dimerization protein MLX
chr1_-_186680411 1.64 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr1_+_27959943 1.64 ENST00000675575.1
ENST00000373884.6
XK related 8
chr11_-_3840942 1.63 ENST00000351018.5
ras homolog family member G
chr3_-_18425295 1.63 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chrX_-_20266606 1.61 ENST00000643085.1
ENST00000645270.1
ENST00000644368.1
ribosomal protein S6 kinase A3
chr2_-_239309202 1.61 ENST00000446876.1
histone deacetylase 4
chr7_+_101817601 1.61 ENST00000292535.12
ENST00000546411.7
ENST00000549414.6
ENST00000550008.6
ENST00000556210.1
cut like homeobox 1
chr8_-_69834970 1.59 ENST00000260126.9
solute carrier organic anion transporter family member 5A1
chr5_-_150412743 1.59 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr9_+_114323098 1.58 ENST00000259396.9
orosomucoid 1
chr9_+_79572715 1.57 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chr19_-_51417581 1.57 ENST00000442846.7
ENST00000530476.1
sialic acid binding Ig like lectin 10
chr20_+_1135217 1.56 ENST00000381898.5
proteasome inhibitor subunit 1
chr4_+_73869385 1.54 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr6_+_31571957 1.54 ENST00000454783.5
lymphotoxin alpha
chr19_-_2042066 1.52 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chr3_+_57227831 1.52 ENST00000495803.5
ENST00000444459.1
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
chr14_+_24147474 1.52 ENST00000324103.11
ENST00000559260.5
ring finger protein 31
chr13_+_108269880 1.51 ENST00000542136.1
TNF superfamily member 13b
chr6_-_32853813 1.51 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr12_-_9760893 1.50 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr6_-_31645025 1.49 ENST00000438149.5
BAG cochaperone 6
chr17_+_42567084 1.49 ENST00000435881.7
MAX dimerization protein MLX
chr14_+_64503708 1.48 ENST00000553583.1
zinc finger and BTB domain containing 1
chr17_-_4949037 1.48 ENST00000572383.1
profilin 1
chr14_+_51847116 1.47 ENST00000553560.5
G protein subunit gamma 2
chr18_-_75208417 1.46 ENST00000581620.1
ENST00000582437.1
zinc binding alcohol dehydrogenase domain containing 2
chr7_+_121328991 1.45 ENST00000222462.3
Wnt family member 16
chr10_-_124092445 1.44 ENST00000346248.7
carbohydrate sulfotransferase 15
chr5_-_151080978 1.44 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr1_-_64966488 1.44 ENST00000342505.5
ENST00000673254.1
Janus kinase 1
chr18_-_31162849 1.43 ENST00000257197.7
ENST00000257198.6
desmocollin 1
chr2_-_191020960 1.42 ENST00000432058.1
signal transducer and activator of transcription 1
chr16_+_6019663 1.42 ENST00000422070.8
RNA binding fox-1 homolog 1
chr7_+_7567009 1.41 ENST00000433056.5
meiosis regulator for oocyte development
chrX_-_15854791 1.41 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chr12_+_48106094 1.40 ENST00000546755.5
ENST00000549366.5
ENST00000642730.1
ENST00000552792.5
phosphofructokinase, muscle
chr18_+_13218195 1.40 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr1_+_10033180 1.39 ENST00000377153.5
ubiquitination factor E4B
chr6_-_32853618 1.39 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr17_-_60391968 1.39 ENST00000393003.7
ubiquitin specific peptidase 32
chr1_-_7940825 1.38 ENST00000377507.8
TNF receptor superfamily member 9
chr10_-_124092390 1.38 ENST00000628426.1
carbohydrate sulfotransferase 15
chr5_-_151087660 1.38 ENST00000522226.5
TNFAIP3 interacting protein 1
chr7_+_7566974 1.37 ENST00000456533.1
meiosis regulator for oocyte development
chr9_+_79573162 1.37 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr1_-_41662298 1.36 ENST00000643665.1
HIVEP zinc finger 3
chr10_-_29634964 1.36 ENST00000375398.6
ENST00000355867.8
supervillin
chr19_-_51417791 1.36 ENST00000353836.9
sialic acid binding Ig like lectin 10
chr19_-_51417700 1.35 ENST00000529627.1
ENST00000439889.6
sialic acid binding Ig like lectin 10
chr17_+_21288029 1.34 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr19_-_45322867 1.32 ENST00000221476.4
creatine kinase, M-type
chr13_+_108269629 1.32 ENST00000430559.5
ENST00000375887.9
TNF superfamily member 13b
chr11_+_65525067 1.32 ENST00000525364.5
ENST00000270176.10
ENST00000420247.6
ENST00000533862.5
ENST00000524944.5
SCY1 like pseudokinase 1
chr10_+_13099585 1.30 ENST00000378764.6
optineurin
chr17_-_19004727 1.29 ENST00000388995.11
family with sequence similarity 83 member G
chr3_-_187737943 1.29 ENST00000438077.1
BCL6 transcription repressor
chrX_-_132218124 1.29 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr5_-_135895834 1.29 ENST00000274520.2
interleukin 9
chr17_+_40309189 1.29 ENST00000577646.5
retinoic acid receptor alpha
chr19_+_496454 1.28 ENST00000346144.8
ENST00000215637.8
ENST00000382683.8
mucosal vascular addressin cell adhesion molecule 1
chr10_-_71773513 1.27 ENST00000394957.8
V-set immunoregulatory receptor
chr11_+_1839452 1.27 ENST00000381906.5
troponin I2, fast skeletal type
chrX_-_139222777 1.26 ENST00000448673.1
fibroblast growth factor 13
chr11_-_66546228 1.25 ENST00000526986.5
zinc finger DHHC-type containing 24
chr19_-_41353904 1.25 ENST00000221930.6
transforming growth factor beta 1
chr8_-_109974688 1.24 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr11_+_65525413 1.24 ENST00000527009.5
SCY1 like pseudokinase 1
chr20_-_37527723 1.23 ENST00000397135.1
ENST00000397137.5
BLCAP apoptosis inducing factor
chr5_-_151087131 1.22 ENST00000315050.11
ENST00000523338.5
ENST00000522100.5
TNFAIP3 interacting protein 1
chr6_-_31645503 1.22 ENST00000453833.5
BAG cochaperone 6
chr2_-_241508318 1.21 ENST00000439101.5
ENST00000424537.5
ENST00000401869.5
ENST00000436402.5
serine/threonine kinase 25
chr17_+_7687416 1.21 ENST00000457584.6
WD repeat containing antisense to TP53
chr5_+_119268689 1.19 ENST00000274456.6
TNF alpha induced protein 8
chr9_+_131228109 1.19 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
nucleoporin 214
chr5_-_96807899 1.19 ENST00000503921.5
ENST00000508227.5
ENST00000507154.1
ENST00000443439.7
endoplasmic reticulum aminopeptidase 1
chr14_-_35404650 1.18 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr7_-_127392060 1.17 ENST00000436992.5
zinc finger protein 800
chr15_-_44711306 1.17 ENST00000682850.1
PAT1 homolog 2
chr1_+_156153568 1.17 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A
chr19_-_38899800 1.16 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr10_+_13100075 1.16 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr1_-_155688294 1.14 ENST00000311573.9
YY1 associated protein 1
chr7_-_1555473 1.14 ENST00000414730.5
transmembrane protein 184A
chr17_-_7251691 1.13 ENST00000574322.6
CTD nuclear envelope phosphatase 1
chr1_+_37474572 1.12 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr20_+_9514562 1.11 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr17_-_7205116 1.10 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr9_+_132161672 1.10 ENST00000372179.7
netrin G2
chr10_+_12349685 1.09 ENST00000378845.5
calcium/calmodulin dependent protein kinase ID
chr3_+_9649433 1.06 ENST00000353332.9
ENST00000420925.5
ENST00000296003.9
ENST00000351233.9
myotubularin related protein 14
chr14_+_95876430 1.06 ENST00000678517.1
TCL1 upstream neural differentiation-associated RNA
chr2_+_207529892 1.06 ENST00000432329.6
ENST00000445803.5
cAMP responsive element binding protein 1
chr1_+_155687946 1.06 ENST00000471642.6
ENST00000471214.5
death associated protein 3
chr14_+_102777555 1.05 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr19_+_41860236 1.05 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
ribosomal protein S19
chr19_-_38899710 1.05 ENST00000447739.1
ENST00000407552.5
sirtuin 2
chr1_-_155990062 1.04 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr14_+_51847145 1.03 ENST00000615906.4
G protein subunit gamma 2
chr14_+_95876385 1.03 ENST00000504119.1
TCL1 upstream neural differentiation-associated RNA
chr6_+_33410739 1.03 ENST00000428274.5
PHD finger protein 1
chr2_+_162318884 1.02 ENST00000446271.5
ENST00000429691.6
grancalcin
chr20_+_36461747 1.02 ENST00000340491.8
DLG associated protein 4
chr1_+_15526813 1.02 ENST00000375838.5
ENST00000616884.4
ENST00000375849.5
ENST00000375847.8
DnaJ heat shock protein family (Hsp40) member C16
chr20_-_63472505 1.02 ENST00000360480.7
ENST00000344462.8
ENST00000625514.2
ENST00000629241.2
ENST00000629676.2
ENST00000370224.5
ENST00000359125.7
ENST00000344425.8
ENST00000626839.2
potassium voltage-gated channel subfamily Q member 2
chr10_+_122374685 1.02 ENST00000368990.7
ENST00000368989.6
ENST00000463663.6
pleckstrin homology domain containing A1
chr3_+_159839847 1.02 ENST00000445224.6
schwannomin interacting protein 1
chr2_-_152098670 1.02 ENST00000636129.1
ENST00000636785.1
ENST00000636496.1
calcium voltage-gated channel auxiliary subunit beta 4
chr19_-_17847962 1.01 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr12_-_57430778 1.01 ENST00000448732.1
ENST00000634871.1
R3H domain containing 2
chr6_+_29723421 1.01 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr4_-_76023489 1.00 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr12_+_56338873 1.00 ENST00000228534.6
interleukin 23 subunit alpha
chr17_+_42288429 1.00 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr19_+_17952266 0.99 ENST00000609922.2
potassium calcium-activated channel subfamily N member 1
chr12_+_12717359 0.98 ENST00000614874.2
ENST00000228872.9
cyclin dependent kinase inhibitor 1B
chr7_-_106284524 0.97 ENST00000681936.1
ENST00000680786.1
ENST00000681550.1
nicotinamide phosphoribosyltransferase
chr17_-_7251286 0.97 ENST00000576613.5
CTD nuclear envelope phosphatase 1
chr1_+_27234612 0.96 ENST00000319394.8
ENST00000361771.7
WD and tetratricopeptide repeats 1
chr2_-_43226594 0.96 ENST00000282388.4
ZFP36 ring finger protein like 2
chrX_-_21758021 0.96 ENST00000646008.1
small muscle protein X-linked
chrX_-_40097945 0.96 ENST00000378444.9
ENST00000406200.4
BCL6 corepressor
chr14_+_64503943 0.96 ENST00000556965.1
ENST00000554015.5
zinc finger and BTB domain containing 1
chr8_+_72537219 0.95 ENST00000523207.2
potassium voltage-gated channel subfamily B member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
1.9 7.5 GO:1990108 protein linear deubiquitination(GO:1990108)
1.3 4.0 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
1.0 3.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
1.0 4.0 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.0 2.9 GO:0046967 cytosol to ER transport(GO:0046967)
0.8 3.1 GO:0032499 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419)
0.8 8.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 2.8 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.7 2.0 GO:0045062 extrathymic T cell selection(GO:0045062)
0.6 2.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.6 1.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.6 1.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.6 1.7 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.6 1.7 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 1.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.5 1.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 6.0 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.5 1.6 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.5 3.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.5 3.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.5 11.2 GO:0048535 lymph node development(GO:0048535)
0.5 2.4 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.5 1.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.5 4.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 2.2 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.4 2.6 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.4 3.6 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4 3.6 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.4 1.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.4 7.5 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.4 2.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 1.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 1.0 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.3 2.0 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.3 3.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 2.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 2.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 3.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.3 1.8 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 0.9 GO:0060516 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 1.5 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.2 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.3 2.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 0.8 GO:1990697 protein depalmitoleylation(GO:1990697)
0.3 2.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 1.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.3 2.4 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.3 1.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.2 2.7 GO:1904327 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 1.4 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 4.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 2.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.7 GO:0045357 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 0.6 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.2 2.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.7 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.2 2.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 1.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 1.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 0.6 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.2 0.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.2 1.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 1.5 GO:0023035 CD40 signaling pathway(GO:0023035) protein linear polyubiquitination(GO:0097039)
0.2 1.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 1.6 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.2 3.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.2 0.6 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 1.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 2.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.0 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.4 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 1.3 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.6 GO:0033058 directional locomotion(GO:0033058)
0.1 2.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 2.8 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 2.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 11.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.8 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 0.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 1.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 1.8 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 0.8 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.3 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.6 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 1.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.3 GO:0034059 response to anoxia(GO:0034059)
0.1 0.3 GO:1902075 cellular response to salt(GO:1902075)
0.1 1.0 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.1 0.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 2.0 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.0 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.3 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 2.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 1.2 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 4.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 0.7 GO:0072553 terminal button organization(GO:0072553)
0.1 2.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 1.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 2.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 1.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.6 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 7.9 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.6 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 5.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.0 GO:0033327 luteinization(GO:0001553) Leydig cell differentiation(GO:0033327)
0.1 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 2.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.1 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.0 0.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 1.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.3 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 1.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.5 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.4 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 1.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 1.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 1.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 3.8 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 1.8 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.9 GO:0045116 protein neddylation(GO:0045116)
0.0 3.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 7.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 1.3 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 2.1 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 4.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 2.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 3.4 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.6 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 2.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 1.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.4 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 3.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 1.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.5 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.1 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.0 1.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.0 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.8 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.9 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 1.0 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 3.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 2.0 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.7 GO:0001756 somitogenesis(GO:0001756)
0.0 1.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.6 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.6 2.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.5 2.6 GO:0019815 B cell receptor complex(GO:0019815)
0.5 5.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 3.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 2.9 GO:0042825 TAP complex(GO:0042825)
0.4 8.4 GO:0036449 microtubule minus-end(GO:0036449)
0.3 3.1 GO:0072687 meiotic spindle(GO:0072687)
0.3 2.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 1.2 GO:0008537 proteasome activator complex(GO:0008537)
0.3 5.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 1.4 GO:0016938 kinesin I complex(GO:0016938)
0.3 2.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 2.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 1.5 GO:0005927 muscle tendon junction(GO:0005927)
0.2 0.7 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 2.4 GO:0070552 BRISC complex(GO:0070552)
0.2 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 2.1 GO:0042611 MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612)
0.2 3.7 GO:0061700 GATOR2 complex(GO:0061700)
0.2 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.5 GO:0071797 LUBAC complex(GO:0071797)
0.2 3.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 2.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 2.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 7.5 GO:0097542 ciliary tip(GO:0097542)
0.1 2.1 GO:0005861 troponin complex(GO:0005861)
0.1 0.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 3.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 6.1 GO:0008180 COP9 signalosome(GO:0008180)
0.1 4.0 GO:0071437 invadopodium(GO:0071437)
0.1 1.2 GO:0060091 kinocilium(GO:0060091)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 1.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 10.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.9 GO:0097342 ripoptosome(GO:0097342)
0.1 3.2 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.1 0.3 GO:0070993 translation preinitiation complex(GO:0070993)
0.1 6.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.1 17.4 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0001940 male pronucleus(GO:0001940)
0.0 1.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 6.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 2.3 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 3.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.1 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.4 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 5.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 6.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.2 GO:0005657 replication fork(GO:0005657)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 1.9 GO:0034702 ion channel complex(GO:0034702)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.9 8.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.8 2.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.6 4.6 GO:0046979 TAP2 binding(GO:0046979)
0.6 1.7 GO:0035375 zymogen binding(GO:0035375)
0.5 2.0 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.4 2.2 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.4 1.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 8.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 2.8 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.3 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 1.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 2.6 GO:1990763 arrestin family protein binding(GO:1990763)
0.3 1.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 16.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 0.8 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.3 2.4 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 4.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 7.8 GO:0043495 protein anchor(GO:0043495)
0.2 2.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 4.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.8 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.2 1.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.2 1.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 10.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 0.3 GO:0070905 serine binding(GO:0070905)
0.2 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.2 3.1 GO:0050700 CARD domain binding(GO:0050700)
0.2 1.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 1.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 2.7 GO:0045159 myosin II binding(GO:0045159)
0.2 4.4 GO:0043422 protein kinase B binding(GO:0043422)
0.2 2.2 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.1 GO:0031014 troponin T binding(GO:0031014)
0.2 2.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.1 0.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.0 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 12.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 2.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 3.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.5 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 0.2 GO:0035877 death effector domain binding(GO:0035877) cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 3.2 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.1 GO:0048156 tau protein binding(GO:0048156)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 4.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 5.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 7.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 14.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 2.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 1.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.0 GO:0030506 ankyrin binding(GO:0030506)
0.0 15.7 GO:0005525 GTP binding(GO:0005525)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 2.5 GO:0043621 protein self-association(GO:0043621)
0.0 3.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0061598 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 6.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.2 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 4.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 5.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 11.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.2 9.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 8.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 5.5 PID IL5 PATHWAY IL5-mediated signaling events
0.1 8.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 2.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 8.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.8 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 2.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 5.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 2.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.8 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 18.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 8.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 7.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 1.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 8.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 5.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 7.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 4.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 4.5 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 2.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 5.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 7.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 5.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 5.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 2.0 REACTOME KINESINS Genes involved in Kinesins
0.0 4.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 2.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.4 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein