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Illumina Body Map 2 (GSE30611)

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Results for NKX1-1

Z-value: 0.59

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Transcription factors associated with NKX1-1

Gene Symbol Gene ID Gene Info
ENSG00000235608.2 NK1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX1-1hg38_v1_chr4_-_1406442_1406442-0.421.6e-02Click!

Activity profile of NKX1-1 motif

Sorted Z-values of NKX1-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_16347637 3.33 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr12_+_16347665 3.26 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
microsomal glutathione S-transferase 1
chr12_+_16347102 3.07 ENST00000536371.5
ENST00000010404.6
microsomal glutathione S-transferase 1
chr14_+_32329256 1.32 ENST00000280979.9
A-kinase anchoring protein 6
chr10_+_119029711 1.31 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr14_+_32329341 1.28 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr3_+_186842687 1.22 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chrX_+_19343893 1.14 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr12_+_48105466 1.00 ENST00000549003.5
ENST00000550924.6
phosphofructokinase, muscle
chr13_-_109786567 0.94 ENST00000375856.5
insulin receptor substrate 2
chr11_-_2885728 0.82 ENST00000647251.1
ENST00000380725.2
ENST00000430149.3
ENST00000414822.8
ENST00000440480.8
cyclin dependent kinase inhibitor 1C
chr11_+_19712823 0.78 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr6_-_166627244 0.77 ENST00000265678.9
ribosomal protein S6 kinase A2
chr7_+_6009222 0.76 ENST00000400479.6
ENST00000223029.8
ENST00000395236.2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr19_-_14117729 0.72 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr21_+_33025927 0.56 ENST00000430860.1
ENST00000382357.4
ENST00000333337.3
oligodendrocyte transcription factor 2
chr15_-_78234513 0.54 ENST00000558130.1
ENST00000258873.9
acyl-CoA synthetase bubblegum family member 1
chr6_-_82247697 0.50 ENST00000306270.12
ENST00000610980.4
inhibitor of Bruton tyrosine kinase
chr19_+_1261091 0.49 ENST00000588411.5
cold inducible RNA binding protein
chr17_+_47209375 0.48 ENST00000572303.1
myosin light chain 4
chr6_-_84763355 0.44 ENST00000606621.1
T-box transcription factor 18
chr16_-_10942443 0.44 ENST00000570440.2
ENST00000331808.5
Dexi homolog
chr13_-_35476682 0.42 ENST00000379919.6
mab-21 like 1
chr9_+_34646589 0.41 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chr18_+_58221535 0.40 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr9_+_34646654 0.38 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr7_+_26291941 0.38 ENST00000412416.5
sorting nexin 10
chrX_+_152831054 0.38 ENST00000370274.8
NAD(P) dependent steroid dehydrogenase-like
chr7_-_6009072 0.37 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr17_+_1762814 0.36 ENST00000570731.5
serpin family F member 1
chr17_+_47209338 0.36 ENST00000393450.5
myosin light chain 4
chr11_-_2139382 0.36 ENST00000416167.7
insulin like growth factor 2
chr7_-_16420623 0.36 ENST00000676325.1
CDP-L-ribitol pyrophosphorylase A
chr2_+_86720282 0.35 ENST00000283632.5
required for meiotic nuclear division 5 homolog A
chr1_+_240091866 0.34 ENST00000319653.14
formin 2
chr21_-_36542600 0.34 ENST00000399136.5
claudin 14
chr10_+_97446194 0.34 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
zinc finger DHHC-type palmitoyltransferase 16
chr8_+_93916849 0.32 ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_4967790 0.30 ENST00000575142.5
ENST00000206020.8
sperm associated antigen 7
chr19_+_9835292 0.30 ENST00000247970.9
ENST00000587625.5
ENST00000588695.5
peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr9_+_121567057 0.30 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr2_+_62705866 0.30 ENST00000263991.9
EH domain binding protein 1
chr1_-_159862648 0.28 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr3_-_105869387 0.28 ENST00000438603.6
ENST00000443752.2
Cbl proto-oncogene B
chr4_-_145180496 0.28 ENST00000447906.8
OTU deubiquitinase 4
chr9_+_34646627 0.28 ENST00000556278.1
novel protein (GALT-IL11RA readthrough)
chr4_-_53365976 0.28 ENST00000401642.8
ENST00000388940.8
ENST00000503450.1
sec1 family domain containing 2
chr18_+_36129444 0.28 ENST00000543127.5
elongator acetyltransferase complex subunit 2
chr11_-_59615673 0.28 ENST00000263847.6
oxysterol binding protein
chr19_+_10252206 0.27 ENST00000253099.11
ENST00000393733.6
ENST00000588502.5
mitochondrial ribosomal protein L4
chr11_-_47176851 0.27 ENST00000629231.2
ENST00000526342.5
ENST00000528444.5
ENST00000530596.5
ENST00000525398.5
ENST00000524782.6
ENST00000527927.5
ENST00000525314.5
ADP ribosylation factor GTPase activating protein 2
chr17_-_47189176 0.27 ENST00000531206.5
ENST00000527547.5
ENST00000575483.5
ENST00000066544.8
cell division cycle 27
chr10_+_97446137 0.26 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
zinc finger DHHC-type palmitoyltransferase 16
chr12_+_6852115 0.26 ENST00000389231.9
ENST00000229268.13
ENST00000542087.1
ubiquitin specific peptidase 5
chr15_-_64093746 0.25 ENST00000557835.5
ENST00000380290.7
ENST00000300030.8
ENST00000559950.1
cytosolic iron-sulfur assembly component 2A
chr2_+_62705644 0.25 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EH domain binding protein 1
chr19_-_4065732 0.24 ENST00000601588.1
zinc finger and BTB domain containing 7A
chr1_-_51330527 0.24 ENST00000439482.6
tetratricopeptide repeat domain 39A
chr6_+_132538290 0.24 ENST00000434551.2
trace amine associated receptor 9
chr19_-_46634685 0.24 ENST00000300873.4
G protein subunit gamma 8
chr16_+_590200 0.23 ENST00000563109.1
RAB40C, member RAS oncogene family
chr12_-_91058016 0.23 ENST00000266719.4
keratocan
chr2_-_238288600 0.23 ENST00000254657.8
period circadian regulator 2
chr2_-_166375969 0.22 ENST00000454569.6
ENST00000409672.5
sodium voltage-gated channel alpha subunit 9
chr2_-_46915745 0.22 ENST00000649435.1
ENST00000409105.5
ENST00000319466.9
ENST00000409973.5
ENST00000409913.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr11_-_4608138 0.21 ENST00000533021.1
tripartite motif containing 68
chr21_-_31038476 0.21 ENST00000382822.2
keratin associated protein 19-8
chr7_-_6009019 0.20 ENST00000382321.5
ENST00000265849.12
PMS1 homolog 2, mismatch repair system component
chr2_+_216659600 0.20 ENST00000456764.1
insulin like growth factor binding protein 2
chrX_+_155216452 0.20 ENST00000286428.7
VHL binding protein 1
chr17_-_59155235 0.20 ENST00000581068.5
spindle and kinetochore associated complex subunit 2
chr17_-_10469558 0.20 ENST00000255381.2
myosin heavy chain 4
chr11_-_111871530 0.19 ENST00000614444.4
ENST00000616540.5
ALG9 alpha-1,2-mannosyltransferase
chr1_-_51330553 0.19 ENST00000680483.1
ENST00000371747.7
tetratricopeptide repeat domain 39A
chr9_+_72577788 0.18 ENST00000645208.2
transmembrane channel like 1
chr7_+_26291850 0.18 ENST00000338523.9
ENST00000446848.6
sorting nexin 10
chr5_-_116554858 0.18 ENST00000509665.1
semaphorin 6A
chr2_-_46916020 0.18 ENST00000409800.5
ENST00000409218.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr12_-_55296569 0.18 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr7_+_71132123 0.18 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chr13_+_35476740 0.18 ENST00000537702.5
neurobeachin
chr2_+_149330506 0.17 ENST00000334166.9
LY6/PLAUR domain containing 6
chr11_+_73272201 0.17 ENST00000393590.3
pyrimidinergic receptor P2Y6
chr1_-_51331315 0.16 ENST00000262676.9
tetratricopeptide repeat domain 39A
chr7_+_26291898 0.16 ENST00000416246.5
sorting nexin 10
chr17_-_59155164 0.16 ENST00000583380.5
ENST00000580541.1
ENST00000578105.1
ENST00000330137.12
ENST00000437036.6
spindle and kinetochore associated complex subunit 2
chr1_-_221742074 0.15 ENST00000366899.4
dual specificity phosphatase 10
chr1_+_155308930 0.15 ENST00000465559.5
ENST00000612683.1
farnesyl diphosphate synthase
chr11_-_72112750 0.15 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
anaphase promoting complex subunit 15
chr14_+_94174334 0.15 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr3_+_158801926 0.14 ENST00000622669.4
ENST00000392813.8
ENST00000415822.8
ENST00000651862.1
ENST00000264266.12
major facilitator superfamily domain containing 1
chr17_+_47209035 0.13 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr14_+_94174284 0.13 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chr7_-_73842508 0.13 ENST00000297873.9
methyltransferase like 27
chr8_+_93917045 0.13 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_100119291 0.13 ENST00000431404.2
TATA-box binding protein associated factor 6
chr16_+_590056 0.13 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr10_-_97445850 0.12 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr11_-_72112669 0.12 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chr11_-_111871271 0.12 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr12_+_102120240 0.12 ENST00000537257.5
ENST00000392911.6
PARP1 binding protein
chr3_-_105868964 0.11 ENST00000394030.8
Cbl proto-oncogene B
chr10_+_1049476 0.11 ENST00000358220.5
WD repeat domain 37
chr15_-_74906872 0.11 ENST00000562698.5
family with sequence similarity 219 member B
chr9_+_113463697 0.11 ENST00000317613.10
regulator of G protein signaling 3
chr11_-_62754141 0.10 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr3_-_105869035 0.10 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr12_+_64405046 0.10 ENST00000540203.5
exportin for tRNA
chr11_-_4608226 0.10 ENST00000300747.10
ENST00000526337.5
tripartite motif containing 68
chr19_-_8005590 0.09 ENST00000407627.7
ENST00000593807.1
ELAV like RNA binding protein 1
chr19_+_56141317 0.09 ENST00000592949.5
zinc finger protein 444
chr4_-_53365941 0.09 ENST00000611795.1
sec1 family domain containing 2
chr1_+_161721563 0.08 ENST00000367948.6
Fc receptor like B
chr11_+_73272332 0.08 ENST00000540124.6
ENST00000536225.2
pyrimidinergic receptor P2Y6
chr5_+_67004618 0.08 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr13_-_110242694 0.08 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr11_-_106022209 0.08 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr4_+_3074661 0.08 ENST00000355072.11
huntingtin
chr15_+_64094060 0.07 ENST00000560829.5
sorting nexin 1
chrX_-_23743201 0.07 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chr3_+_39387795 0.07 ENST00000642978.1
solute carrier family 25 member 38
chr8_-_167024 0.06 ENST00000320901.4
olfactory receptor family 4 subfamily F member 21
chr1_-_197146688 0.06 ENST00000294732.11
assembly factor for spindle microtubules
chr11_-_125111708 0.06 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr6_-_31862809 0.06 ENST00000375631.5
neuraminidase 1
chr19_+_49766962 0.05 ENST00000354293.10
ENST00000359032.9
adaptor related protein complex 2 subunit alpha 1
chr20_-_41618362 0.05 ENST00000373222.3
ENST00000373233.8
chromodomain helicase DNA binding protein 6
chrX_+_55000329 0.05 ENST00000374987.4
apurinic/apyrimidinic endodeoxyribonuclease 2
chr9_+_72577369 0.05 ENST00000651183.1
transmembrane channel like 1
chr17_-_42185452 0.04 ENST00000293330.1
hypocretin neuropeptide precursor
chr1_+_174874434 0.04 ENST00000478442.5
ENST00000465412.5
RAB GTPase activating protein 1 like
chr19_-_45782388 0.04 ENST00000458663.6
DM1 protein kinase
chrX_+_137566119 0.04 ENST00000287538.10
Zic family member 3
chr10_-_124418912 0.03 ENST00000368845.6
ENST00000539214.5
ornithine aminotransferase
chr22_-_38755458 0.03 ENST00000405510.5
ENST00000433561.5
Sad1 and UNC84 domain containing 2
chr10_-_54801179 0.03 ENST00000373955.5
protocadherin related 15
chr19_-_45782479 0.03 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr6_-_73395133 0.02 ENST00000441145.1
oocyte expressed protein
chr11_+_119334511 0.02 ENST00000311413.5
ring finger protein 26
chr5_+_64505981 0.02 ENST00000334025.3
regulator of G protein signaling 7 binding protein
chr10_-_1049110 0.02 ENST00000381344.8
isopentenyl-diphosphate delta isomerase 1
chr7_+_100049765 0.01 ENST00000456748.6
ENST00000292450.9
ENST00000438937.1
ENST00000543588.2
zinc finger and SCAN domain containing 21
chr14_-_24242567 0.00 ENST00000558476.5
TERF1 interacting nuclear factor 2
chr7_+_120988683 0.00 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.7 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.2 GO:0072244 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 2.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 0.8 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.0 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.2 0.8 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.4 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.8 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.9 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.2 GO:1900920 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 1.3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.3 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 9.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 1.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.3 GO:1990032 parallel fiber(GO:1990032)
0.0 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.7 GO:0043295 glutathione binding(GO:0043295)
0.3 1.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 1.0 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 2.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.8 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.6 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors