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Illumina Body Map 2 (GSE30611)

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Results for NKX1-2_RAX

Z-value: 0.74

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Transcription factors associated with NKX1-2_RAX

Gene Symbol Gene ID Gene Info
ENSG00000229544.9 NK1 homeobox 2
ENSG00000134438.10 retina and anterior neural fold homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAXhg38_v1_chr18_-_59273379_59273429-0.451.0e-02Click!
NKX1-2hg38_v1_chr10_-_124450027_124450043-0.067.6e-01Click!

Activity profile of NKX1-2_RAX motif

Sorted Z-values of NKX1-2_RAX motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_115593570 2.70 ENST00000539310.5
plastin 3
chr12_-_21910853 2.06 ENST00000544039.5
ATP binding cassette subfamily C member 9
chr12_-_91180365 2.01 ENST00000547937.5
decorin
chr1_+_186296267 1.72 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chrX_+_43656289 1.71 ENST00000338702.4
monoamine oxidase A
chr10_+_97446194 1.68 ENST00000370846.8
ENST00000352634.8
ENST00000353979.7
ENST00000370842.6
ENST00000345745.9
zinc finger DHHC-type palmitoyltransferase 16
chrX_-_21658324 1.65 ENST00000379499.3
kelch like family member 34
chr6_+_125153649 1.54 ENST00000304877.17
ENST00000368402.9
ENST00000368388.6
ENST00000534000.6
TPD52 like 1
chr14_+_32329341 1.54 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr14_+_32329256 1.53 ENST00000280979.9
A-kinase anchoring protein 6
chr2_+_216659600 1.40 ENST00000456764.1
insulin like growth factor binding protein 2
chr13_-_110242694 1.37 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr13_-_35476682 1.36 ENST00000379919.6
mab-21 like 1
chr6_+_54099565 1.29 ENST00000511678.5
muscular LMNA interacting protein
chr9_-_92404559 1.27 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr3_-_151316795 1.27 ENST00000260843.5
G protein-coupled receptor 87
chr4_+_76435216 1.26 ENST00000296043.7
shroom family member 3
chr10_+_97446137 1.22 ENST00000370854.7
ENST00000393760.6
ENST00000414567.5
zinc finger DHHC-type palmitoyltransferase 16
chr1_-_151831768 1.21 ENST00000318247.7
RAR related orphan receptor C
chr3_-_105869035 1.21 ENST00000447441.6
ENST00000403724.5
ENST00000405772.5
Cbl proto-oncogene B
chr6_+_54099538 1.19 ENST00000447836.6
muscular LMNA interacting protein
chr3_-_105868964 1.17 ENST00000394030.8
Cbl proto-oncogene B
chr6_+_54018910 1.17 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
muscular LMNA interacting protein
chr20_+_45416551 1.05 ENST00000639292.1
phosphatidylinositol glycan anchor biosynthesis class T
chr17_+_1762814 1.04 ENST00000570731.5
serpin family F member 1
chr1_+_160400543 1.04 ENST00000368061.3
VANGL planar cell polarity protein 2
chr4_-_145180496 1.03 ENST00000447906.8
OTU deubiquitinase 4
chr10_+_24466487 1.01 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr16_-_55833085 0.99 ENST00000360526.8
carboxylesterase 1
chr9_+_121567057 0.98 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2 interacting protein
chr7_+_71132123 0.98 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chr2_-_189582012 0.95 ENST00000427419.5
ENST00000455320.5
solute carrier family 40 member 1
chr1_-_151831837 0.91 ENST00000652040.1
RAR related orphan receptor C
chr7_+_120988683 0.89 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr19_+_49487510 0.88 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
ribosomal protein L13a
chr16_-_55833186 0.82 ENST00000361503.8
ENST00000422046.6
carboxylesterase 1
chr14_+_19719015 0.78 ENST00000557414.1
olfactory receptor family 4 subfamily N member 2
chr6_-_166627244 0.77 ENST00000265678.9
ribosomal protein S6 kinase A2
chr7_+_101127095 0.76 ENST00000223095.5
serpin family E member 1
chr3_+_186842687 0.75 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr3_-_120682113 0.74 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr11_-_18236795 0.74 ENST00000278222.7
serum amyloid A4, constitutive
chr1_+_162366896 0.74 ENST00000420220.1
novel protein
chr2_-_219399981 0.73 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr3_-_105869387 0.70 ENST00000438603.6
ENST00000443752.2
Cbl proto-oncogene B
chr5_+_67004618 0.66 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr7_-_7535863 0.65 ENST00000399429.8
collagen type XXVIII alpha 1 chain
chr6_+_132538290 0.64 ENST00000434551.2
trace amine associated receptor 9
chr5_-_35938572 0.62 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr11_+_112176364 0.62 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr12_+_6904962 0.61 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr17_-_7263959 0.59 ENST00000571932.2
claudin 7
chr12_+_6904733 0.59 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr16_+_82034978 0.59 ENST00000563491.5
hydroxysteroid 17-beta dehydrogenase 2
chr1_-_16978276 0.58 ENST00000375534.7
microfibril associated protein 2
chr19_-_6424772 0.57 ENST00000619396.4
ENST00000398148.7
KH-type splicing regulatory protein
chr3_+_184135343 0.56 ENST00000648915.2
ENST00000432569.2
ENST00000647909.1
eukaryotic translation initiation factor 2B subunit epsilon
chr1_-_159862648 0.52 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr7_-_107803215 0.52 ENST00000340010.10
ENST00000453332.1
solute carrier family 26 member 3
chr1_+_42682388 0.52 ENST00000321358.12
ENST00000332220.10
Y-box binding protein 1
chr5_-_103562775 0.51 ENST00000230792.7
ENST00000507423.1
nudix hydrolase 12
chr19_-_3985451 0.51 ENST00000309311.7
eukaryotic translation elongation factor 2
chr19_+_48445795 0.51 ENST00000598711.1
glutamate rich WD repeat containing 1
chr11_-_125111708 0.51 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chrX_+_19343893 0.50 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr11_-_125111579 0.50 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr11_-_59615673 0.48 ENST00000263847.6
oxysterol binding protein
chr6_+_30720335 0.47 ENST00000327892.13
tubulin beta class I
chr11_+_72189528 0.47 ENST00000312293.9
folate receptor alpha
chr4_-_102827948 0.46 ENST00000394804.6
ENST00000394801.8
ubiquitin conjugating enzyme E2 D3
chr19_-_45782479 0.46 ENST00000447742.6
ENST00000354227.9
ENST00000291270.9
ENST00000683086.1
ENST00000343373.10
DM1 protein kinase
chr7_+_138460238 0.46 ENST00000343526.9
tripartite motif containing 24
chr14_-_99480831 0.45 ENST00000331768.10
ENST00000630307.2
SET domain containing 3, actin histidine methyltransferase
chr5_-_95554944 0.45 ENST00000513823.5
ENST00000649566.1
ENST00000358746.7
ENST00000514952.5
tetratricopeptide repeat domain 37
chr12_+_26195313 0.44 ENST00000422622.3
sarcospan
chr6_-_111606260 0.43 ENST00000340026.10
TRAF3 interacting protein 2
chr8_-_42768602 0.43 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr6_-_31862809 0.42 ENST00000375631.5
neuraminidase 1
chr4_-_102827723 0.42 ENST00000349311.12
ubiquitin conjugating enzyme E2 D3
chr4_-_102828159 0.41 ENST00000394803.9
ubiquitin conjugating enzyme E2 D3
chrX_+_136536099 0.40 ENST00000440515.5
ENST00000456412.1
vestigial like family member 1
chr5_-_83673544 0.39 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr3_+_28349146 0.39 ENST00000420223.5
zinc finger CW-type and PWWP domain containing 2
chr13_-_109786567 0.37 ENST00000375856.5
insulin receptor substrate 2
chr19_-_9107475 0.37 ENST00000641081.1
olfactory receptor family 7 subfamily G member 2
chr16_-_20691256 0.37 ENST00000307493.8
acyl-CoA synthetase medium chain family member 1
chr11_+_72189659 0.37 ENST00000393681.6
folate receptor alpha
chr9_+_116687295 0.37 ENST00000450136.2
ENST00000373983.2
ENST00000411410.1
tripartite motif containing 32
chr2_-_238288600 0.37 ENST00000254657.8
period circadian regulator 2
chr10_-_97445850 0.36 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr1_-_211134135 0.36 ENST00000638983.1
ENST00000271751.10
ENST00000639952.1
novel protein
potassium voltage-gated channel subfamily H member 1
chr6_-_111605859 0.36 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3 interacting protein 2
chr15_-_43589942 0.36 ENST00000429176.5
diphosphoinositol pentakisphosphate kinase 1
chr9_+_122370523 0.35 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chrM_+_9207 0.35 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr17_-_5035418 0.35 ENST00000254853.10
ENST00000424747.1
solute carrier family 52 member 1
chr1_-_211134061 0.34 ENST00000639602.1
ENST00000638498.1
ENST00000367007.5
novel protein
potassium voltage-gated channel subfamily H member 1
chr6_+_160121859 0.33 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr12_-_9869345 0.33 ENST00000228438.3
C-type lectin domain family 2 member B
chr19_-_6424802 0.33 ENST00000600480.2
KH-type splicing regulatory protein
chr4_-_102828022 0.32 ENST00000502690.5
ubiquitin conjugating enzyme E2 D3
chr14_-_52791597 0.31 ENST00000216410.8
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr9_-_5339874 0.31 ENST00000223862.2
relaxin 1
chr11_-_4368386 0.31 ENST00000624801.3
olfactory receptor family 52 subfamily B member 4
chr17_-_10469558 0.31 ENST00000255381.2
myosin heavy chain 4
chr20_+_45420585 0.31 ENST00000639239.1
phosphatidylinositol glycan anchor biosynthesis class T
chr12_+_64405046 0.30 ENST00000540203.5
exportin for tRNA
chr15_+_101812202 0.30 ENST00000332238.5
olfactory receptor family 4 subfamily F member 15
chr14_-_99480784 0.30 ENST00000329331.7
ENST00000436070.6
SET domain containing 3, actin histidine methyltransferase
chr11_-_122116215 0.29 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr18_+_58341038 0.29 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr10_-_104085793 0.29 ENST00000650263.1
collagen type XVII alpha 1 chain
chr19_-_45782388 0.28 ENST00000458663.6
DM1 protein kinase
chr12_+_16347637 0.27 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr11_+_118527463 0.27 ENST00000302783.10
tetratricopeptide repeat domain 36
chr9_+_72577788 0.27 ENST00000645208.2
transmembrane channel like 1
chr10_-_104085847 0.27 ENST00000648076.2
collagen type XVII alpha 1 chain
chr21_-_31038476 0.27 ENST00000382822.2
keratin associated protein 19-8
chr4_-_102828048 0.27 ENST00000508249.1
ubiquitin conjugating enzyme E2 D3
chr17_-_42185452 0.26 ENST00000293330.1
hypocretin neuropeptide precursor
chr11_+_19712823 0.25 ENST00000396085.6
ENST00000349880.9
neuron navigator 2
chr10_-_104085762 0.25 ENST00000393211.3
collagen type XVII alpha 1 chain
chr6_-_82247697 0.25 ENST00000306270.12
ENST00000610980.4
inhibitor of Bruton tyrosine kinase
chr12_+_8157034 0.24 ENST00000396570.7
zinc finger protein 705A
chr11_-_111871530 0.24 ENST00000614444.4
ENST00000616540.5
ALG9 alpha-1,2-mannosyltransferase
chr19_+_35748549 0.23 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr9_+_34646654 0.23 ENST00000378842.8
galactose-1-phosphate uridylyltransferase
chr17_+_7407838 0.23 ENST00000302926.7
neuroligin 2
chr14_+_67364849 0.23 ENST00000555876.1
eukaryotic translation initiation factor 2 subunit alpha
chr13_+_35476740 0.23 ENST00000537702.5
neurobeachin
chr5_-_126595237 0.23 ENST00000637206.1
ENST00000553117.5
aldehyde dehydrogenase 7 family member A1
chr4_-_73620500 0.22 ENST00000335049.5
Ras association domain family member 6
chr11_-_56748696 0.22 ENST00000641581.1
ENST00000641668.1
olfactory receptor family 9 subfamily G member 4
chr6_+_154039333 0.22 ENST00000428397.6
opioid receptor mu 1
chr8_-_96261579 0.22 ENST00000517720.1
ENST00000523821.5
ENST00000287025.4
mitochondrial transcription termination factor 3
chr9_-_21240002 0.22 ENST00000380222.4
interferon alpha 14
chr19_+_49766962 0.22 ENST00000354293.10
ENST00000359032.9
adaptor related protein complex 2 subunit alpha 1
chr4_-_73620629 0.21 ENST00000342081.7
Ras association domain family member 6
chr2_+_90038848 0.21 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr11_+_124183219 0.21 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr9_+_122371036 0.20 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr7_+_100049765 0.20 ENST00000456748.6
ENST00000292450.9
ENST00000438937.1
ENST00000543588.2
zinc finger and SCAN domain containing 21
chr3_+_195720867 0.20 ENST00000436408.6
mucin 20, cell surface associated
chr7_-_100119291 0.20 ENST00000431404.2
TATA-box binding protein associated factor 6
chr9_+_34646589 0.20 ENST00000450095.6
galactose-1-phosphate uridylyltransferase
chrX_+_77899440 0.20 ENST00000373335.4
ENST00000475465.1
ENST00000650309.2
ENST00000647835.1
cytochrome c oxidase subunit 7B
chr1_+_27934980 0.20 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr20_-_1466904 0.20 ENST00000476071.5
NSFL1 cofactor
chr7_-_100119840 0.20 ENST00000437822.6
TATA-box binding protein associated factor 6
chr7_+_21543020 0.19 ENST00000409508.8
ENST00000620169.4
ENST00000328843.10
dynein axonemal heavy chain 11
chr20_-_1466822 0.19 ENST00000353088.6
ENST00000216879.9
NSFL1 cofactor
chr11_-_111871271 0.19 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr4_-_106368772 0.18 ENST00000638719.4
GIMAP family P-loop NTPase domain containing 1
chr17_-_4967790 0.18 ENST00000575142.5
ENST00000206020.8
sperm associated antigen 7
chr12_+_18261511 0.18 ENST00000538779.6
ENST00000433979.6
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr7_-_100119323 0.18 ENST00000523306.5
ENST00000344095.8
ENST00000417349.5
ENST00000493322.5
ENST00000520135.5
ENST00000460673.2
ENST00000453269.7
ENST00000452041.5
ENST00000452438.6
ENST00000451699.5
TATA-box binding protein associated factor 6
chr5_+_132873660 0.17 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr12_-_10807286 0.17 ENST00000240615.3
taste 2 receptor member 8
chr8_-_100559702 0.17 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46
chr7_-_100119317 0.17 ENST00000440225.5
TATA-box binding protein associated factor 6
chr9_+_34646627 0.16 ENST00000556278.1
novel protein (GALT-IL11RA readthrough)
chr9_+_34329545 0.15 ENST00000379158.7
nudix hydrolase 2
chr21_-_7793954 0.15 ENST00000624951.1
small integral membrane protein 34B
chr21_-_36542600 0.15 ENST00000399136.5
claudin 14
chr1_+_54715837 0.15 ENST00000371281.4
tetratricopeptide repeat domain 4
chr19_+_37317929 0.15 ENST00000589801.1
zinc finger protein 875
chr9_+_72577369 0.15 ENST00000651183.1
transmembrane channel like 1
chr4_-_67963441 0.13 ENST00000508048.6
transmembrane serine protease 11A
chr19_+_8630622 0.13 ENST00000671902.1
ENST00000673603.1
NFIL3 like basic leucine zipper
chr9_-_21187671 0.12 ENST00000421715.2
interferon alpha 4
chrX_-_41665766 0.12 ENST00000643043.2
ENST00000486402.1
ENST00000646087.2
calcium/calmodulin dependent serine protein kinase
chr15_+_49170200 0.12 ENST00000396509.6
galactokinase 2
chr11_+_28108248 0.12 ENST00000406787.7
ENST00000403099.5
ENST00000407364.8
methyltransferase like 15
chr8_-_81461574 0.12 ENST00000379071.4
fatty acid binding protein 9
chr12_-_55296569 0.11 ENST00000358433.3
olfactory receptor family 6 subfamily C member 6
chr15_+_49170237 0.11 ENST00000560031.6
ENST00000558145.5
ENST00000544523.5
ENST00000560138.5
galactokinase 2
chr9_+_122371014 0.11 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr3_-_11643871 0.11 ENST00000430365.7
vestigial like family member 4
chr1_-_152414256 0.11 ENST00000271835.3
cornulin
chrX_+_152831054 0.10 ENST00000370274.8
NAD(P) dependent steroid dehydrogenase-like
chr18_+_24460630 0.10 ENST00000256906.5
histamine receptor H4
chr8_+_9555900 0.10 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
tankyrase
chr2_+_74455077 0.10 ENST00000431187.5
ENST00000233331.12
ENST00000409917.5
ENST00000409493.3
INO80 complex subunit B
chr1_+_45688165 0.10 ENST00000372025.5
transmembrane protein 69
chr11_+_92969651 0.09 ENST00000257068.3
ENST00000528076.1
melatonin receptor 1B
chr14_+_55027200 0.09 ENST00000395472.2
ENST00000555846.2
suppressor of cytokine signaling 4
chr6_-_93419545 0.09 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPH receptor A7
chr22_-_28094135 0.08 ENST00000442232.1
tetratricopeptide repeat domain 28
chr1_+_192636121 0.08 ENST00000543215.5
ENST00000391995.7
regulator of G protein signaling 13
chr6_+_49499965 0.08 ENST00000545705.1
glycine-N-acyltransferase like 3
chr13_+_48037692 0.08 ENST00000258662.3
nudix hydrolase 15
chr10_+_18260715 0.07 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr10_+_35605337 0.07 ENST00000321660.2
gap junction protein delta 4
chr17_-_73262352 0.07 ENST00000397671.1
cleavage and polyadenylation specific factor 4 like
chr8_+_104223344 0.07 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chrX_-_152830721 0.06 ENST00000370277.5
centrin 2
chr18_+_24460655 0.06 ENST00000426880.2
histamine receptor H4
chr1_-_158426237 0.06 ENST00000641042.1
olfactory receptor family 10 subfamily K member 2
chr9_-_134068012 0.06 ENST00000303407.12
bromodomain containing 3
chr21_-_34423951 0.06 ENST00000450895.2
small integral membrane protein 34A

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.3 3.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.0 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 0.8 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.3 1.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 1.0 GO:0060448 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 0.8 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.7 GO:0072244 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.6 GO:0046247 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.2 0.5 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 3.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 1.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 2.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.3 GO:0045176 apical protein localization(GO:0045176)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 0.4 GO:0051941 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 2.1 GO:0036315 cellular response to sterol(GO:0036315)
0.1 1.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 2.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.8 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.9 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 1.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 1.4 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.1 GO:1904907 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 2.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 1.9 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0060187 cell pole(GO:0060187)
0.2 1.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.0 GO:1990032 parallel fiber(GO:1990032)
0.2 3.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 2.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.5 GO:0055087 Ski complex(GO:0055087)
0.1 1.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.9 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.0 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 3.6 GO:0016605 PML body(GO:0016605)
0.0 2.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 1.5 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 2.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.0 GO:0097689 iron channel activity(GO:0097689)
0.2 0.7 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.2 0.8 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.6 GO:0008142 oxysterol binding(GO:0008142)
0.2 1.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.3 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.0 3.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 5.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 3.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening