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Illumina Body Map 2 (GSE30611)

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Results for NKX2-2

Z-value: 1.12

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Transcription factors associated with NKX2-2

Gene Symbol Gene ID Gene Info
ENSG00000125820.6 NK2 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-2hg38_v1_chr20_-_21514046_215140700.271.4e-01Click!

Activity profile of NKX2-2 motif

Sorted Z-values of NKX2-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_16600703 2.59 ENST00000616247.4
LIM domain only 3
chr2_+_102337148 2.16 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr3_+_159273235 1.90 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr3_-_33645433 1.65 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chrX_+_136205982 1.48 ENST00000628568.1
four and a half LIM domains 1
chr16_+_23182737 1.47 ENST00000300061.3
sodium channel epithelial 1 subunit gamma
chr2_+_79120474 1.46 ENST00000233735.2
regenerating family member 1 alpha
chr7_+_97732046 1.31 ENST00000350485.8
ENST00000346867.4
ENST00000319273.10
tachykinin precursor 1
chrX_+_106201724 1.28 ENST00000372552.1
PWWP domain containing 3B
chrX_+_153687918 1.26 ENST00000253122.10
solute carrier family 6 member 8
chr1_-_216805367 1.24 ENST00000360012.7
estrogen related receptor gamma
chr11_-_13495984 1.19 ENST00000282091.6
parathyroid hormone
chr4_-_98657635 1.14 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
tetraspanin 5
chr1_-_244859297 1.10 ENST00000483966.3
heterogeneous nuclear ribonucleoprotein U
chr2_-_182522556 1.10 ENST00000435564.5
phosphodiesterase 1A
chr1_-_243843226 1.08 ENST00000336199.9
AKT serine/threonine kinase 3
chr3_-_33645253 1.06 ENST00000333778.10
cytoplasmic linker associated protein 2
chr7_-_77199808 1.03 ENST00000248598.6
fibrinogen like 2
chr2_-_142131004 1.03 ENST00000434794.1
ENST00000389484.8
LDL receptor related protein 1B
chr20_-_57266606 1.01 ENST00000450594.6
ENST00000395863.8
bone morphogenetic protein 7
chr9_-_83267230 1.00 ENST00000328788.5
FERM domain containing 3
chr2_-_182522703 1.00 ENST00000410103.1
phosphodiesterase 1A
chr14_+_64113084 0.99 ENST00000673797.1
spectrin repeat containing nuclear envelope protein 2
chr11_-_26722051 0.93 ENST00000396005.8
solute carrier family 5 member 12
chr1_-_243843164 0.91 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT serine/threonine kinase 3
chr7_-_93226449 0.91 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr22_-_50085378 0.90 ENST00000442311.1
modulator of VRAC current 1
chr22_-_50085331 0.89 ENST00000395876.6
modulator of VRAC current 1
chr1_+_207034366 0.88 ENST00000545806.5
ENST00000618513.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr10_-_119536533 0.86 ENST00000392865.5
regulator of G protein signaling 10
chr7_-_904994 0.86 ENST00000453175.6
ArfGAP with dual PH domains 1
chr5_-_59356962 0.85 ENST00000405755.6
phosphodiesterase 4D
chr10_-_103153609 0.85 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr12_-_262828 0.83 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr2_-_162152239 0.83 ENST00000418842.7
glucagon
chr1_-_72100930 0.82 ENST00000306821.3
neuronal growth regulator 1
chr9_-_94593810 0.82 ENST00000375337.4
fructose-bisphosphatase 2
chr1_+_84164293 0.82 ENST00000370684.5
ENST00000436133.5
protein kinase cAMP-activated catalytic subunit beta
chrX_+_76427666 0.81 ENST00000361470.4
MAGE family member E1
chr2_-_177314907 0.81 ENST00000443132.1
ENST00000625449.2
ENST00000586532.5
novel transcript
nuclear factor, erythroid 2 like 2
chr12_-_10826358 0.81 ENST00000240619.2
taste 2 receptor member 10
chr14_-_51096029 0.81 ENST00000298355.7
tripartite motif containing 9
chr12_-_89656093 0.81 ENST00000359142.7
ATPase plasma membrane Ca2+ transporting 1
chr1_+_84164370 0.80 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
protein kinase cAMP-activated catalytic subunit beta
chr11_-_129024157 0.80 ENST00000392657.7
Rho GTPase activating protein 32
chr3_+_68006224 0.79 ENST00000496687.1
TAFA chemokine like family member 1
chr21_+_15842393 0.79 ENST00000449491.1
ubiquitin specific peptidase 25
chr13_-_44474296 0.78 ENST00000611198.4
TSC22 domain family member 1
chr4_+_87006988 0.78 ENST00000307808.10
AF4/FMR2 family member 1
chr2_+_169798841 0.76 ENST00000260956.9
ENST00000417292.5
small RNA binding exonuclease protection factor La
chrX_+_101488044 0.76 ENST00000423738.4
armadillo repeat containing X-linked 4
chr4_-_40475749 0.75 ENST00000507180.5
RNA binding motif protein 47
chr11_-_790062 0.75 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr9_+_128685062 0.74 ENST00000409104.7
SET nuclear proto-oncogene
chr20_+_58888779 0.74 ENST00000488546.6
ENST00000667293.2
ENST00000481039.6
ENST00000467321.6
GNAS complex locus
chr18_-_3845321 0.74 ENST00000539435.5
ENST00000400147.6
DLG associated protein 1
chr12_-_10723307 0.73 ENST00000279550.11
ENST00000228251.9
Y-box binding protein 3
chr12_+_100357068 0.72 ENST00000323346.10
solute carrier family 17 member 8
chr9_+_127642343 0.72 ENST00000626333.1
syntaxin binding protein 1
chr11_-_128842467 0.71 ENST00000392664.2
potassium inwardly rectifying channel subfamily J member 1
chr7_+_37683847 0.71 ENST00000447769.1
G protein-coupled receptor 141
chr20_-_57266342 0.70 ENST00000395864.7
bone morphogenetic protein 7
chr4_-_46388713 0.70 ENST00000507069.5
gamma-aminobutyric acid type A receptor subunit alpha2
chr5_+_83471764 0.70 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr6_+_31528956 0.69 ENST00000376191.3
mitochondrial coiled-coil domain 1
chr5_-_88884525 0.69 ENST00000502983.5
myocyte enhancer factor 2C
chr1_+_84164669 0.69 ENST00000450730.5
protein kinase cAMP-activated catalytic subunit beta
chr4_+_112818088 0.69 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr1_+_171512032 0.69 ENST00000426496.6
proline rich coiled-coil 2C
chr12_+_40310431 0.68 ENST00000681696.1
leucine rich repeat kinase 2
chr15_+_67067780 0.68 ENST00000679624.1
SMAD family member 3
chr22_-_43171744 0.67 ENST00000494035.1
tubulin tyrosine ligase like 12
chr3_+_151873634 0.67 ENST00000362032.6
succinate receptor 1
chr9_-_15510289 0.66 ENST00000397519.6
PC4 and SFRS1 interacting protein 1
chr7_-_44225893 0.65 ENST00000425809.5
calcium/calmodulin dependent protein kinase II beta
chr1_-_226739271 0.65 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr7_+_37683733 0.64 ENST00000334425.2
ENST00000450180.5
G protein-coupled receptor 141
chr4_+_85778681 0.63 ENST00000395183.6
Rho GTPase activating protein 24
chr2_-_55049184 0.62 ENST00000357376.7
reticulon 4
chr18_+_34978415 0.62 ENST00000588349.6
microtubule associated protein RP/EB family member 2
chr12_-_84911178 0.62 ENST00000681688.1
solute carrier family 6 member 15
chr3_-_69200711 0.62 ENST00000478263.5
ENST00000462512.1
FERM domain containing 4B
chr8_-_100950549 0.62 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr12_-_54295748 0.61 ENST00000540264.2
ENST00000312156.8
nuclear factor, erythroid 2
chr11_-_85627322 0.61 ENST00000376104.7
discs large MAGUK scaffold protein 2
chr18_+_58221535 0.60 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr21_-_44230089 0.60 ENST00000643466.1
inducible T cell costimulator ligand
chr12_+_68809002 0.60 ENST00000539479.6
ENST00000393415.7
ENST00000523991.5
ENST00000543323.5
ENST00000393416.7
MDM2 proto-oncogene
chr4_-_46124046 0.58 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr9_-_28670285 0.58 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr8_+_91249307 0.58 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr12_-_119877300 0.58 ENST00000392521.7
citron rho-interacting serine/threonine kinase
chr1_-_154178174 0.57 ENST00000302206.9
tropomyosin 3
chr12_-_71157872 0.57 ENST00000546561.2
tetraspanin 8
chr13_-_36370171 0.56 ENST00000355182.8
spartin
chr8_-_94208548 0.56 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr13_+_111203052 0.56 ENST00000426768.2
Rho guanine nucleotide exchange factor 7
chr16_-_21278282 0.56 ENST00000572914.2
crystallin mu
chrX_+_123961696 0.56 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr14_+_64113054 0.54 ENST00000673869.1
spectrin repeat containing nuclear envelope protein 2
chrX_-_85379659 0.54 ENST00000262753.9
POF1B actin binding protein
chr15_+_78873030 0.54 ENST00000558502.5
mortality factor 4 like 1
chr11_-_35360050 0.53 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
solute carrier family 1 member 2
chr3_+_178807293 0.53 ENST00000358316.7
ENST00000617329.1
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr13_-_75366973 0.53 ENST00000648194.1
TBC1 domain family member 4
chr2_+_17539964 0.53 ENST00000457525.5
visinin like 1
chr11_-_11353241 0.53 ENST00000528848.3
casein kinase 2 alpha 3
chr19_+_49644830 0.53 ENST00000601038.5
ENST00000595242.3
SR-related CTD associated factor 1
chr4_+_113292925 0.52 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chrX_-_72943837 0.52 ENST00000615063.2
DMRT like family C1
chr8_-_7056729 0.52 ENST00000330590.4
defensin alpha 5
chr21_+_29300111 0.52 ENST00000451655.5
BTB domain and CNC homolog 1
chr6_+_158312459 0.52 ENST00000367097.8
TUB like protein 4
chr7_+_37683817 0.51 ENST00000476620.1
ependymin related 1
chr3_-_197184131 0.51 ENST00000452595.5
discs large MAGUK scaffold protein 1
chrX_-_71255060 0.51 ENST00000373988.5
ENST00000373998.5
zinc finger MYM-type containing 3
chrM_+_12329 0.50 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chrX_+_47232866 0.50 ENST00000218348.7
ENST00000377107.7
ubiquitin specific peptidase 11
chr4_-_23881282 0.49 ENST00000613098.4
PPARG coactivator 1 alpha
chr5_+_83471668 0.49 ENST00000342785.8
ENST00000343200.9
versican
chr6_-_152302132 0.49 ENST00000537033.1
spectrin repeat containing nuclear envelope protein 1
chr4_+_122339221 0.49 ENST00000442707.1
KIAA1109
chr9_+_126335200 0.49 ENST00000402437.2
multivesicular body subunit 12B
chr13_-_98978022 0.49 ENST00000682017.1
ENST00000442173.5
ENST00000627024.2
dedicator of cytokinesis 9
chr6_-_149746497 0.48 ENST00000367404.8
ENST00000340413.7
ENST00000543637.1
nucleoporin 43
chrX_+_123962040 0.48 ENST00000435215.5
stromal antigen 2
chr21_-_15065815 0.48 ENST00000638122.1
nuclear receptor interacting protein 1
chr5_+_126423176 0.48 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr12_+_8513499 0.48 ENST00000299665.3
C-type lectin domain family 4 member D
chrX_-_15315615 0.48 ENST00000380470.7
ENST00000480796.6
ankyrin repeat and SOCS box containing 11
chr11_-_26721999 0.48 ENST00000280467.10
solute carrier family 5 member 12
chr11_-_84273188 0.48 ENST00000330014.11
ENST00000418306.6
ENST00000531015.5
discs large MAGUK scaffold protein 2
chr15_+_78872881 0.48 ENST00000559930.5
ENST00000426013.7
mortality factor 4 like 1
chr10_-_59753388 0.48 ENST00000430431.5
myoregulin
chr21_-_30492008 0.48 ENST00000334063.6
keratin associated protein 19-3
chr12_-_11186937 0.48 ENST00000334266.1
taste 2 receptor member 42
chr14_-_100375457 0.47 ENST00000556295.5
ENST00000554820.5
tryptophanyl-tRNA synthetase 1
chr12_-_119877270 0.47 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chrX_-_11290478 0.46 ENST00000380717.7
Rho GTPase activating protein 6
chr12_-_75209814 0.46 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr3_-_197226351 0.46 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr1_+_53894181 0.45 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
iodothyronine deiodinase 1
chr5_+_126423363 0.45 ENST00000285689.8
GRAM domain containing 2B
chr14_+_32494227 0.45 ENST00000554410.5
A-kinase anchoring protein 6
chr17_+_50746614 0.45 ENST00000513969.5
ENST00000503728.1
LUC7 like 3 pre-mRNA splicing factor
chr2_+_151409878 0.45 ENST00000453091.6
ENST00000428287.6
ENST00000444746.7
ENST00000243326.9
ENST00000414861.6
replication timing regulatory factor 1
chr4_-_110641920 0.44 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr10_-_59753444 0.44 ENST00000594536.5
ENST00000414264.6
myoregulin
chr5_+_108747879 0.44 ENST00000281092.9
FER tyrosine kinase
chr18_-_66604076 0.44 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr5_-_59039454 0.44 ENST00000358923.10
phosphodiesterase 4D
chr7_-_26995237 0.44 ENST00000432747.1
src kinase associated phosphoprotein 2
chr15_-_89893963 0.44 ENST00000560940.5
ENST00000336418.9
ENST00000558011.5
adaptor related protein complex 3 subunit sigma 2
chr15_+_78872954 0.44 ENST00000558746.5
ENST00000558830.5
ENST00000559345.5
mortality factor 4 like 1
chrX_+_72776873 0.43 ENST00000334036.10
DMRT like family C1B
chr19_-_14835162 0.43 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr17_+_68515082 0.43 ENST00000588178.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_+_47130782 0.43 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr1_+_32200587 0.43 ENST00000373602.10
ENST00000421922.6
ENST00000681230.1
coiled-coil domain containing 28B
chr5_+_83471736 0.42 ENST00000265077.8
versican
chr7_+_2354078 0.42 ENST00000431643.5
eukaryotic translation initiation factor 3 subunit B
chr17_+_68525795 0.42 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr5_+_126423122 0.42 ENST00000515200.5
GRAM domain containing 2B
chr1_+_101238090 0.42 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr5_-_59276109 0.41 ENST00000503258.5
phosphodiesterase 4D
chr8_-_140800535 0.41 ENST00000521986.5
ENST00000523539.5
protein tyrosine kinase 2
chr5_-_11588842 0.41 ENST00000503622.5
catenin delta 2
chr9_+_121207774 0.41 ENST00000373823.7
gelsolin
chr4_+_94455245 0.41 ENST00000508216.5
ENST00000514743.5
PDZ and LIM domain 5
chr3_+_69762703 0.41 ENST00000433517.5
melanocyte inducing transcription factor
chr1_-_31065671 0.40 ENST00000440538.6
ENST00000424085.6
ENST00000257075.9
ENST00000373747.7
ENST00000426105.7
ENST00000525843.5
ENST00000373742.6
pumilio RNA binding family member 1
chr14_-_100375592 0.40 ENST00000555031.5
tryptophanyl-tRNA synthetase 1
chr1_+_117420597 0.39 ENST00000449370.6
mannosidase alpha class 1A member 2
chr2_-_144518261 0.39 ENST00000392861.6
zinc finger E-box binding homeobox 2
chr10_+_27532521 0.39 ENST00000683924.1
RAB18, member RAS oncogene family
chr5_+_163503075 0.38 ENST00000280969.9
methionine adenosyltransferase 2B
chr14_-_100375333 0.38 ENST00000557297.5
ENST00000555813.5
ENST00000392882.7
ENST00000557135.5
ENST00000556698.5
ENST00000554509.5
ENST00000555410.5
tryptophanyl-tRNA synthetase 1
chr12_-_75209701 0.38 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr8_-_140764386 0.38 ENST00000520151.5
ENST00000519024.5
ENST00000519465.5
protein tyrosine kinase 2
chr8_-_61646863 0.38 ENST00000519678.5
aspartate beta-hydroxylase
chr18_-_3845292 0.38 ENST00000400145.6
DLG associated protein 1
chr1_-_244862381 0.38 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U
chr2_-_27335403 0.38 ENST00000454704.5
general transcription factor IIIC subunit 2
chr14_-_100375602 0.37 ENST00000553395.5
ENST00000553545.5
ENST00000344102.9
ENST00000556338.5
ENST00000553934.1
tryptophanyl-tRNA synthetase 1
chr7_-_99552092 0.37 ENST00000449309.2
family with sequence similarity 200 member A
chr5_+_83471925 0.37 ENST00000502527.2
versican
chr19_+_13024626 0.37 ENST00000586873.1
nuclear factor I X
chr2_+_151410090 0.36 ENST00000430328.6
replication timing regulatory factor 1
chr11_+_65182413 0.35 ENST00000531068.5
ENST00000527699.5
ENST00000533909.5
ENST00000527323.5
calpain 1
chr3_-_151249114 0.35 ENST00000424796.6
purinergic receptor P2Y14
chr7_-_22194709 0.35 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr16_+_53207981 0.35 ENST00000565803.2
chromodomain helicase DNA binding protein 9
chr5_-_11589019 0.35 ENST00000511377.5
catenin delta 2
chr1_-_246507237 0.35 ENST00000490107.6
SET and MYND domain containing 3
chr10_+_13586933 0.34 ENST00000417658.5
ENST00000378572.8
ENST00000320054.4
pre-mRNA processing factor 18
chr5_+_119476530 0.34 ENST00000645099.1
ENST00000513628.5
hydroxysteroid 17-beta dehydrogenase 4
chr6_-_152302095 0.34 ENST00000540663.5
spectrin repeat containing nuclear envelope protein 1
chr20_+_11890785 0.34 ENST00000399006.6
ENST00000405977.5
BTB domain containing 3
chr2_-_32039776 0.34 ENST00000342166.10
ENST00000295066.3
dpy-30 histone methyltransferase complex regulatory subunit
chr8_+_109540602 0.33 ENST00000530629.5
ENST00000620557.4
estrogen receptor binding site associated antigen 9

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0072134 nephrogenic mesenchyme morphogenesis(GO:0072134)
0.4 1.3 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.3 1.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.3 2.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 2.6 GO:0097338 response to clozapine(GO:0097338)
0.3 1.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.2 1.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 2.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.7 GO:1903124 regulation of thioredoxin peroxidase activity(GO:1903123) negative regulation of thioredoxin peroxidase activity(GO:1903124) negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation(GO:1903125) Wnt signalosome assembly(GO:1904887) negative regulation of peroxidase activity(GO:2000469)
0.2 0.6 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.2 0.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 0.9 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2 1.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 2.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.5 GO:0061567 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.2 1.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 0.5 GO:1903210 cellular response to nitrite(GO:0071250) response to nitrite(GO:0080033) glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) response to resveratrol(GO:1904638) cellular response to resveratrol(GO:1904639) positive regulation of progesterone biosynthetic process(GO:2000184)
0.2 0.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 0.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 1.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.5 GO:0000964 mitochondrial RNA 5'-end processing(GO:0000964)
0.1 0.6 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.4 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.8 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 0.9 GO:0007403 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.8 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.7 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.6 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 2.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.8 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 2.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.5 GO:0019075 virus maturation(GO:0019075)
0.1 0.4 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 1.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.5 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.8 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 2.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.8 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549)
0.1 1.0 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0015820 leucine transport(GO:0015820)
0.0 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.8 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.8 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 1.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.8 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.1 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.0 0.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 1.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 1.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.6 GO:0006972 hyperosmotic response(GO:0006972)
0.0 0.5 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0019323 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.6 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 1.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0099400 cytoplasmic side of mitochondrial outer membrane(GO:0032473) caveola neck(GO:0099400)
0.2 2.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.0 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.5 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.2 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 3.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 2.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 1.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.8 GO:0000322 storage vacuole(GO:0000322)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0044307 dendritic branch(GO:0044307)
0.0 1.0 GO:0043219 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.6 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 2.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 1.8 GO:0031985 Golgi cisterna(GO:0031985)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.4 1.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.3 2.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 0.8 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.2 0.7 GO:0036479 GTP-dependent protein kinase activity(GO:0034211) peroxidase inhibitor activity(GO:0036479)
0.2 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.8 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.6 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.4 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 1.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.3 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.6 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 3.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 1.5 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 1.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.3 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 1.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 2.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 3.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.5 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 1.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.1 ST GAQ PATHWAY G alpha q Pathway
0.0 4.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 1.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 5.6 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 3.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT