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Illumina Body Map 2 (GSE30611)

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Results for NKX2-3

Z-value: 1.26

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Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
ENSG00000119919.11 NK2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-3hg38_v1_chr10_+_99532927_995329530.154.0e-01Click!

Activity profile of NKX2-3 motif

Sorted Z-values of NKX2-3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_101568350 3.94 ENST00000550514.5
myosin binding protein C1
chr4_+_94455245 3.24 ENST00000508216.5
ENST00000514743.5
PDZ and LIM domain 5
chr13_-_44474250 3.20 ENST00000472477.1
TSC22 domain family member 1
chr12_+_101594849 3.18 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr1_-_237945275 2.69 ENST00000604646.1
MT-RNR2 like 11
chr1_-_109389886 2.45 ENST00000493736.5
sortilin 1
chrX_-_21758021 2.27 ENST00000646008.1
small muscle protein X-linked
chr7_+_123655857 2.24 ENST00000458573.3
ENST00000456238.2
leiomodin 2
chrX_-_21758097 2.24 ENST00000379494.4
small muscle protein X-linked
chr4_-_176241671 2.18 ENST00000512254.1
ankyrin repeat and SOCS box containing 5
chr10_-_75109172 1.95 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr6_-_46080332 1.94 ENST00000185206.12
chloride intracellular channel 5
chr3_+_35679690 1.87 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21
chrX_+_103774385 1.87 ENST00000494475.5
proteolipid protein 1
chr16_+_31214088 1.81 ENST00000613872.1
tripartite motif containing 72
chr7_+_55964959 1.81 ENST00000437587.5
nipsnap homolog 2
chr10_+_97572771 1.68 ENST00000370655.6
ENST00000455090.1
ankyrin repeat domain 2
chrX_+_103773709 1.66 ENST00000434483.5
proteolipid protein 1
chr22_+_44031345 1.66 ENST00000444029.5
parvin beta
chr10_+_97572493 1.64 ENST00000307518.9
ENST00000298808.9
ankyrin repeat domain 2
chr3_+_98763331 1.56 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr9_+_128203371 1.52 ENST00000475805.5
ENST00000372923.8
ENST00000341179.11
ENST00000393594.7
dynamin 1
chr11_+_10305370 1.51 ENST00000528544.1
adrenomedullin
chr3_+_63443306 1.45 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr17_+_60149966 1.40 ENST00000300900.9
carbonic anhydrase 4
chr1_+_202348727 1.40 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr18_-_77127935 1.40 ENST00000581878.5
myelin basic protein
chr17_-_82840010 1.40 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr5_+_150671588 1.38 ENST00000523553.1
myozenin 3
chr2_-_157327699 1.38 ENST00000397283.6
ermin
chr10_-_75109085 1.37 ENST00000607131.5
dual specificity phosphatase 13
chrX_-_109733181 1.34 ENST00000673016.1
acyl-CoA synthetase long chain family member 4
chr21_-_44230089 1.33 ENST00000643466.1
inducible T cell costimulator ligand
chr1_+_202462730 1.33 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr14_-_21048431 1.32 ENST00000555026.5
NDRG family member 2
chr10_+_16436943 1.31 ENST00000423462.6
ENST00000378000.5
phosphotriesterase related
chr5_+_36608146 1.28 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr11_+_10305065 1.27 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr10_-_95441015 1.24 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr18_+_34593312 1.24 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr10_+_69278492 1.23 ENST00000643399.2
hexokinase 1
chr15_+_57599411 1.23 ENST00000569089.1
myocardial zonula adherens protein
chr4_+_112818088 1.17 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr17_-_8152429 1.16 ENST00000581703.1
period circadian regulator 1
chr13_-_44474296 1.13 ENST00000611198.4
TSC22 domain family member 1
chr15_-_43879835 1.12 ENST00000636859.1
FERM domain containing 5
chr10_+_16436996 1.12 ENST00000535784.7
phosphotriesterase related
chr5_-_160419059 1.12 ENST00000297151.9
ENST00000519349.5
ENST00000520664.1
SLU7 homolog, splicing factor
chr10_-_75109106 1.11 ENST00000607487.5
dual specificity phosphatase 13
chr18_-_12656716 1.11 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr18_+_58362467 1.10 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr17_+_60149928 1.10 ENST00000591725.1
carbonic anhydrase 4
chr4_-_89837076 1.07 ENST00000506691.1
synuclein alpha
chr3_+_186842687 1.07 ENST00000444204.2
ENST00000320741.7
adiponectin, C1Q and collagen domain containing
chr5_-_59039454 1.06 ENST00000358923.10
phosphodiesterase 4D
chr12_-_47725483 1.05 ENST00000422538.8
endonuclease, poly(U) specific
chrX_-_109733249 1.04 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
acyl-CoA synthetase long chain family member 4
chr11_-_3671367 1.04 ENST00000534359.1
ENST00000250699.2
cholinergic receptor nicotinic alpha 10 subunit
chr18_-_66604076 1.03 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr12_+_71439789 1.03 ENST00000266674.10
leucine rich repeat containing G protein-coupled receptor 5
chr18_-_46104266 1.02 ENST00000592989.1
ENST00000589869.5
ATP synthase F1 subunit alpha
chr22_-_20859389 1.01 ENST00000449120.1
phosphatidylinositol 4-kinase alpha
chr12_-_84911178 1.01 ENST00000681688.1
solute carrier family 6 member 15
chr17_+_70168610 1.01 ENST00000535240.1
potassium inwardly rectifying channel subfamily J member 2
chr2_-_106160106 1.00 ENST00000479774.5
UDP-glucuronate decarboxylase 1
chr1_-_216723437 0.99 ENST00000459955.5
ENST00000366937.5
ENST00000391890.7
estrogen related receptor gamma
chrX_-_109733220 0.99 ENST00000672282.1
ENST00000340800.7
acyl-CoA synthetase long chain family member 4
chr12_+_78977785 0.97 ENST00000551304.5
synaptotagmin 1
chr12_-_47725558 0.95 ENST00000229003.7
endonuclease, poly(U) specific
chr10_-_102502669 0.94 ENST00000487599.1
actin related protein 1A
chr19_+_32691783 0.94 ENST00000397061.4
nudix hydrolase 19
chr3_-_132035004 0.93 ENST00000429747.6
copine 4
chrX_+_153764178 0.93 ENST00000538966.5
plexin B3
chr20_-_33674359 0.93 ENST00000606690.5
ENST00000439478.5
ENST00000246190.11
ENST00000375238.8
N-terminal EF-hand calcium binding protein 3
chr6_-_11382247 0.91 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr12_-_124914108 0.90 ENST00000541645.1
ENST00000540351.1
ubiquitin C
chr9_-_109119915 0.89 ENST00000374586.8
transmembrane protein 245
chr12_-_47725518 0.88 ENST00000545824.2
endonuclease, poly(U) specific
chr20_+_58389197 0.87 ENST00000475243.6
ENST00000395802.7
VAMP associated protein B and C
chr6_+_69232406 0.87 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr10_+_3104676 0.85 ENST00000415005.6
ENST00000468050.1
phosphofructokinase, platelet
chr19_-_45785659 0.84 ENST00000537879.1
ENST00000596586.5
ENST00000595946.1
DM1 locus, WD repeat containing
novel protein
chr1_+_202348687 0.84 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr12_-_14696571 0.83 ENST00000261170.5
guanylate cyclase 2C
chrX_+_153764233 0.83 ENST00000361971.10
plexin B3
chr5_-_176416222 0.83 ENST00000508425.5
clathrin light chain B
chr12_-_124914056 0.82 ENST00000541272.1
ENST00000535131.1
ubiquitin C
chr10_-_75073627 0.82 ENST00000338487.6
dual specificity phosphatase 29
chr19_+_35651245 0.81 ENST00000590618.1
cytochrome c oxidase subunit 6B1
chr18_-_46104217 0.81 ENST00000590406.5
ENST00000282050.6
ENST00000590324.5
ATP synthase F1 subunit alpha
chr6_+_72366730 0.80 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr1_-_151831837 0.80 ENST00000652040.1
RAR related orphan receptor C
chr4_-_89836963 0.80 ENST00000420646.6
ENST00000673718.1
synuclein alpha
chr17_-_8156320 0.80 ENST00000584202.1
ENST00000354903.9
ENST00000577253.5
period circadian regulator 1
chr19_-_18941184 0.79 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr17_+_47941721 0.79 ENST00000641511.1
pyridoxamine 5'-phosphate oxidase
chr18_-_49460630 0.79 ENST00000675505.1
ENST00000442713.6
ENST00000269445.10
dymeclin
chr8_-_17697654 0.78 ENST00000297488.10
microtubule associated scaffold protein 1
chr4_+_112818032 0.78 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chr3_-_151249114 0.78 ENST00000424796.6
purinergic receptor P2Y14
chr17_+_47941694 0.78 ENST00000584061.6
pyridoxamine 5'-phosphate oxidase
chr6_-_111605859 0.78 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3 interacting protein 2
chr16_+_3135121 0.76 ENST00000576416.5
ENST00000416391.6
zinc finger protein 213
chr11_+_99021066 0.76 ENST00000527185.5
ENST00000528682.5
contactin 5
chr16_+_3134923 0.75 ENST00000574902.5
ENST00000396878.8
zinc finger protein 213
chr17_-_8152380 0.74 ENST00000317276.9
period circadian regulator 1
chr4_-_89836213 0.74 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chrX_-_32155462 0.74 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr3_+_121567924 0.74 ENST00000334384.5
arginine-fifty homeobox
chr2_-_96208815 0.74 ENST00000443962.1
ENST00000337288.10
StAR related lipid transfer domain containing 7
chr10_-_32056376 0.73 ENST00000302418.5
kinesin family member 5B
chr19_+_49644830 0.73 ENST00000601038.5
ENST00000595242.3
SR-related CTD associated factor 1
chr1_-_247536440 0.72 ENST00000366487.4
ENST00000641802.1
olfactory receptor family 2 subfamily C member 3
chr2_-_37231369 0.72 ENST00000446769.1
CCAAT enhancer binding protein zeta
chr20_+_58852710 0.71 ENST00000676826.2
ENST00000371100.9
GNAS complex locus
chr4_-_155376767 0.71 ENST00000450097.1
microtubule associated protein 9
chr11_-_72041945 0.71 ENST00000543009.5
nuclear mitotic apparatus protein 1
chrX_+_131083706 0.71 ENST00000370921.1
Rho GTPase activating protein 36
chr5_-_143434677 0.71 ENST00000504572.5
nuclear receptor subfamily 3 group C member 1
chr22_+_45318480 0.70 ENST00000452238.5
family with sequence similarity 118 member A
chr6_+_167997671 0.70 ENST00000643607.3
kinesin family member 25
chr10_-_27240505 0.70 ENST00000375888.5
ENST00000676732.1
acyl-CoA binding domain containing 5
chr10_-_102502702 0.69 ENST00000369905.9
actin related protein 1A
chr16_+_8642375 0.68 ENST00000562973.1
methyltransferase like 22
chr16_+_75656195 0.68 ENST00000564671.2
TERF2 interacting protein
chr12_+_111099423 0.68 ENST00000397643.3
cut like homeobox 2
chr3_+_98763315 0.67 ENST00000468553.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr3_-_122514876 0.67 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
karyopherin subunit alpha 1
chr3_-_51968387 0.66 ENST00000490063.5
ENST00000468324.5
ENST00000497653.5
ENST00000484633.5
poly(rC) binding protein 4
chr22_+_38057371 0.66 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr1_-_114153863 0.66 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
synaptotagmin 6
chr12_-_124914304 0.66 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.2
ENST00000339647.6
ubiquitin C
chr11_-_72041792 0.65 ENST00000537930.5
nuclear mitotic apparatus protein 1
chr20_+_8649391 0.65 ENST00000475958.1
phospholipase C beta 1
chr4_-_89837106 0.64 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr14_-_60169843 0.64 ENST00000536410.6
ENST00000216500.9
dehydrogenase/reductase 7
chr21_+_32298945 0.64 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr12_+_110614027 0.63 ENST00000550703.6
ENST00000551590.5
tectonic family member 1
chr4_+_88379006 0.63 ENST00000502870.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr13_-_49444004 0.63 ENST00000410043.5
ENST00000409308.6
calcium binding protein 39 like
chr17_+_68525795 0.63 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr1_-_151831768 0.62 ENST00000318247.7
RAR related orphan receptor C
chr18_+_34593392 0.61 ENST00000684377.1
dystrobrevin alpha
chr8_+_90940517 0.61 ENST00000521366.1
N-terminal EF-hand calcium binding protein 1
chr6_+_46793379 0.59 ENST00000230588.9
ENST00000611727.2
meprin A subunit alpha
chr4_+_87832917 0.58 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr11_+_11841953 0.57 ENST00000527733.7
ENST00000399455.2
ubiquitin specific peptidase 47
chr22_+_45318791 0.57 ENST00000424557.1
family with sequence similarity 118 member A
chr1_-_33431079 0.57 ENST00000683057.1
polyhomeotic homolog 2
chr19_-_49061997 0.57 ENST00000593537.1
neurotrophin 4
chr19_-_1401487 0.57 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase
chr1_-_216723410 0.56 ENST00000469486.5
ENST00000481543.1
ENST00000408911.8
estrogen related receptor gamma
chr12_-_119877270 0.56 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr7_+_29146558 0.56 ENST00000439384.5
chimerin 2
chr2_+_63842102 0.56 ENST00000626380.2
ENST00000497883.5
UDP-glucose pyrophosphorylase 2
chr20_+_34194569 0.56 ENST00000568305.5
agouti signaling protein
chr7_-_77199808 0.55 ENST00000248598.6
fibrinogen like 2
chr8_-_139654330 0.55 ENST00000647605.1
potassium two pore domain channel subfamily K member 9
chr10_+_27504234 0.55 ENST00000621805.5
ENST00000535776.6
ENST00000684501.1
ENST00000683797.1
ENST00000682389.1
ENST00000356940.11
ENST00000683755.1
ENST00000682963.1
RAB18, member RAS oncogene family
chr15_+_67548992 0.54 ENST00000354498.9
mitogen-activated protein kinase kinase 5
chr15_-_89893963 0.52 ENST00000560940.5
ENST00000336418.9
ENST00000558011.5
adaptor related protein complex 3 subunit sigma 2
chr19_+_33374312 0.52 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr22_+_24806169 0.52 ENST00000610372.4
ENST00000400358.9
small G protein signaling modulator 1
chr22_+_32043253 0.52 ENST00000266088.9
solute carrier family 5 member 1
chr1_+_32200587 0.51 ENST00000373602.10
ENST00000421922.6
ENST00000681230.1
coiled-coil domain containing 28B
chr2_+_69893940 0.51 ENST00000244227.8
ENST00000409116.5
small nuclear ribonucleoprotein U4/U6.U5 subunit 27
chr4_-_185761562 0.51 ENST00000445343.5
sorbin and SH3 domain containing 2
chr8_-_27478980 0.49 ENST00000520933.7
cholinergic receptor nicotinic alpha 2 subunit
chr12_+_8822610 0.49 ENST00000299698.12
alpha-2-macroglobulin like 1
chr4_+_157221598 0.49 ENST00000505888.1
glutamate ionotropic receptor AMPA type subunit 2
chr7_-_37353659 0.47 ENST00000442504.5
engulfment and cell motility 1
chr15_-_33194696 0.47 ENST00000320930.7
ENST00000616417.5
formin 1
chr1_-_152806628 0.46 ENST00000606576.1
ENST00000607093.2
late cornified envelope 1C
chr2_+_218129277 0.46 ENST00000428565.1
C-X-C motif chemokine receptor 2
chr10_+_1074372 0.46 ENST00000436154.1
WD repeat domain 37
chr5_+_150190035 0.46 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr16_-_75251860 0.46 ENST00000564028.1
BCAR1 scaffold protein, Cas family member
chr2_-_2326161 0.46 ENST00000649810.1
ENST00000648318.1
myelin transcription factor 1 like
chr14_-_88551460 0.46 ENST00000555243.1
protein tyrosine phosphatase non-receptor type 21
chr6_+_31586859 0.45 ENST00000433492.5
leukocyte specific transcript 1
chr22_+_38705737 0.45 ENST00000484657.5
GTP binding protein 1
chr2_+_190137760 0.45 ENST00000396974.2
chromosome 2 open reading frame 88
chr11_+_12674397 0.45 ENST00000527636.7
TEA domain transcription factor 1
chr8_+_133113483 0.45 ENST00000521107.1
thyroglobulin
chr3_-_3179674 0.45 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr6_-_111759910 0.45 ENST00000517419.5
FYN proto-oncogene, Src family tyrosine kinase
chr19_+_41376692 0.44 ENST00000447302.6
ENST00000544232.5
ENST00000542945.5
ENST00000540732.3
transmembrane protein 91
novel protein
chr2_-_2326210 0.44 ENST00000647755.1
myelin transcription factor 1 like
chr2_-_70717736 0.44 ENST00000415348.5
adducin 2
chr4_+_112860981 0.44 ENST00000671704.1
ankyrin 2
chr1_+_248013660 0.44 ENST00000355281.2
olfactory receptor family 2 subfamily L member 5
chr3_+_183253230 0.43 ENST00000326505.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_-_31065671 0.43 ENST00000440538.6
ENST00000424085.6
ENST00000257075.9
ENST00000373747.7
ENST00000426105.7
ENST00000525843.5
ENST00000373742.6
pumilio RNA binding family member 1
chr3_-_171809770 0.43 ENST00000331659.2
phospholipase D1
chr18_-_5521373 0.43 ENST00000580989.5
erythrocyte membrane protein band 4.1 like 3
chr6_+_49499965 0.42 ENST00000545705.1
glycine-N-acyltransferase like 3
chr2_-_178108339 0.42 ENST00000358450.8
phosphodiesterase 11A
chr22_+_24806265 0.42 ENST00000400359.4
small G protein signaling modulator 1
chr4_+_112861053 0.42 ENST00000672221.1
ankyrin 2
chr13_-_23433735 0.41 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 1.1 GO:0072248 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.4 1.8 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.3 2.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 7.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 4.0 GO:0070672 response to interleukin-15(GO:0070672)
0.3 1.2 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.3 1.8 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.3 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.3 1.6 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.3 2.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 1.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 2.8 GO:0097647 progesterone biosynthetic process(GO:0006701) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 1.4 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 0.9 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 2.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.6 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 1.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.6 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.2 0.6 GO:0006601 creatine biosynthetic process(GO:0006601)
0.2 3.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.0 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 1.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 1.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.4 GO:0071988 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.9 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 3.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:1904640 response to methionine(GO:1904640)
0.1 0.7 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 1.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 1.3 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 1.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.3 GO:0072034 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.1 2.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 1.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.6 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 0.3 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.3 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 1.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.0 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 3.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 1.0 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.4 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.9 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.2 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 3.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.6 GO:0051013 microtubule severing(GO:0051013)
0.0 2.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 1.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 1.4 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0060283 female pronucleus assembly(GO:0035038) negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.9 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.4 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 2.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 1.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 1.3 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 3.0 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 3.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 5.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.9 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.3 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 4.5 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 1.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.1 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.2 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.0 0.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 4.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0019082 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:0005927 muscle tendon junction(GO:0005927)
0.2 1.2 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.8 GO:0033269 internode region of axon(GO:0033269)
0.2 7.1 GO:0032982 myosin filament(GO:0032982)
0.2 1.6 GO:0002177 manchette(GO:0002177)
0.2 3.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.0 GO:0019034 viral replication complex(GO:0019034)
0.1 1.4 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.0 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0044207 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.1 0.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.4 GO:0032127 dense core granule membrane(GO:0032127)
0.1 8.6 GO:0031672 A band(GO:0031672)
0.1 2.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.1 2.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.7 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 3.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 3.3 GO:0000791 euchromatin(GO:0000791)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:1990037 Lewy body core(GO:1990037)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 4.8 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 5.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 3.7 GO:0042383 sarcolemma(GO:0042383)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.5 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.8 3.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.6 2.5 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.5 3.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 2.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.4 1.6 GO:0004733 pyridoxamine-phosphate oxidase activity(GO:0004733)
0.4 1.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.3 7.1 GO:0031432 titin binding(GO:0031432)
0.3 1.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 4.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 1.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 1.4 GO:0051373 FATZ binding(GO:0051373)
0.2 0.7 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.2 0.6 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 0.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 1.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 2.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.6 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 1.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 0.6 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.8 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.7 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 2.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.5 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.1 2.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.2 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.2 GO:0016436 rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 4.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0015055 secretin receptor activity(GO:0015055)
0.0 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0086008 G-protein activated inward rectifier potassium channel activity(GO:0015467) voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 3.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383) toxic substance binding(GO:0015643)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 2.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 2.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 4.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID INSULIN PATHWAY Insulin Pathway
0.0 2.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 7.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 3.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 4.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 3.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion