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Illumina Body Map 2 (GSE30611)

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Results for NKX2-8

Z-value: 1.13

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
ENSG00000136327.7 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg38_v1_chr14_-_36582593_36582626-0.009.9e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_107719657 4.21 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr14_-_106235582 2.72 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr12_+_13196718 2.51 ENST00000431267.2
ENST00000542474.5
ENST00000544053.5
ENST00000256951.10
epithelial membrane protein 1
chr14_-_106675544 2.46 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr11_-_19201976 2.34 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
cysteine and glycine rich protein 3
chr14_-_106130061 2.34 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr14_-_106593319 2.31 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr14_-_106335613 2.27 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr12_+_13196777 2.14 ENST00000538364.5
ENST00000396301.7
epithelial membrane protein 1
chr2_-_89010515 2.06 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr3_-_52454032 2.03 ENST00000232975.8
troponin C1, slow skeletal and cardiac type
chr14_-_106269133 1.90 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr14_-_106538331 1.87 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr14_-_105626066 1.83 ENST00000641978.1
ENST00000390543.3
immunoglobulin heavy constant gamma 4 (G4m marker)
chr16_-_33845229 1.81 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr14_-_106579223 1.81 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr14_-_106211453 1.79 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr14_-_106360320 1.74 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr14_-_106811131 1.73 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr5_+_81233314 1.67 ENST00000511719.5
ENST00000437669.5
ENST00000254035.9
ENST00000424301.6
ENST00000505060.1
creatine kinase, mitochondrial 2
chr14_-_106088573 1.60 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr14_-_106791226 1.55 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr10_-_73641450 1.53 ENST00000359322.5
myozenin 1
chr16_+_32995048 1.52 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr6_+_96563117 1.41 ENST00000450218.6
four and a half LIM domains 5
chr14_-_106389858 1.40 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_106507476 1.32 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr15_+_51681483 1.23 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
secretogranin III
chr14_-_106875069 1.22 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr11_-_19202004 1.17 ENST00000648719.1
cysteine and glycine rich protein 3
chr16_+_33827140 1.11 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr14_-_106470788 1.10 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr14_-_105856183 1.07 ENST00000637539.2
ENST00000390559.6
immunoglobulin heavy constant mu
chr4_-_175787382 1.05 ENST00000507520.5
glycoprotein M6A
chr6_-_131951364 1.02 ENST00000367976.4
cellular communication network factor 2
chr17_-_3691887 1.01 ENST00000552050.5
purinergic receptor P2X 5
chr10_-_15719885 1.00 ENST00000378076.4
integrin subunit alpha 8
chr17_-_44911281 0.91 ENST00000638304.1
ENST00000591880.2
ENST00000586125.2
ENST00000639921.1
glial fibrillary acidic protein
chr3_+_111998739 0.90 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr12_-_85836372 0.89 ENST00000361228.5
Ras association domain family member 9
chr17_-_15260752 0.88 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr6_-_32763466 0.87 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chr5_-_79512794 0.86 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chrX_+_103774385 0.85 ENST00000494475.5
proteolipid protein 1
chr19_+_48469354 0.85 ENST00000452733.7
ENST00000641098.1
cytohesin 2
chr11_-_72642450 0.84 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr14_+_63204436 0.76 ENST00000316754.8
ras homolog family member J
chr18_-_58629084 0.74 ENST00000361673.4
alpha kinase 2
chr11_-_72642407 0.74 ENST00000376450.7
phosphodiesterase 2A
chr4_-_46993520 0.73 ENST00000264318.4
gamma-aminobutyric acid type A receptor subunit alpha4
chr18_+_45724127 0.73 ENST00000619403.4
ENST00000587601.5
solute carrier family 14 member 1 (Kidd blood group)
chr3_+_111998915 0.72 ENST00000478951.6
transgelin 3
chrX_+_153687918 0.71 ENST00000253122.10
solute carrier family 6 member 8
chr16_+_172869 0.69 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr19_-_4559663 0.69 ENST00000586582.6
semaphorin 6B
chr22_+_22343185 0.66 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr19_-_48993300 0.66 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr5_+_141094595 0.66 ENST00000622947.1
ENST00000194155.7
ENST00000624874.1
ENST00000625033.1
protocadherin beta 2
chr2_-_63588390 0.64 ENST00000272321.12
ENST00000409562.7
WD repeat containing planar cell polarity effector
chr3_-_196515315 0.64 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr12_-_21657831 0.63 ENST00000450584.5
ENST00000350669.5
ENST00000673047.2
lactate dehydrogenase B
chr5_-_176629943 0.63 ENST00000510387.5
ENST00000506696.1
synuclein beta
chr14_+_63204859 0.63 ENST00000555125.1
ras homolog family member J
chr21_+_32298849 0.62 ENST00000303645.10
melanocortin 2 receptor accessory protein
chr1_+_37807762 0.62 ENST00000373042.5
chromosome 1 open reading frame 122
chr12_-_21657792 0.61 ENST00000396076.5
lactate dehydrogenase B
chr16_+_28863812 0.60 ENST00000684370.1
SH2B adaptor protein 1
chr8_+_66493556 0.59 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
vexin
chr16_+_176659 0.57 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr9_+_35909481 0.56 ENST00000443779.3
small regulatory polypeptide of amino acid response
chr17_-_44968263 0.55 ENST00000253407.4
complement C1q like 1
chr21_+_32298945 0.53 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr10_+_17752185 0.53 ENST00000377495.2
transmembrane protein 236
chr16_+_22490337 0.53 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr19_+_48469306 0.53 ENST00000460595.5
cytohesin 2
chr19_-_33225844 0.52 ENST00000253188.8
solute carrier family 7 member 10
chr6_-_56693294 0.52 ENST00000652573.1
dystonin
chr10_-_13972355 0.52 ENST00000264546.10
FERM domain containing 4A
chr6_+_34466059 0.51 ENST00000620693.4
ENST00000244458.7
ENST00000374043.6
protein kinase C and casein kinase substrate in neurons 1
chr8_-_65842051 0.50 ENST00000401827.8
phosphodiesterase 7A
chr3_+_66998297 0.50 ENST00000484414.5
ENST00000460576.5
ENST00000417314.2
kelch repeat and BTB domain containing 8
chr3_-_8769602 0.48 ENST00000316793.8
ENST00000431493.1
oxytocin receptor
chr3_-_180679468 0.47 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr1_-_94541636 0.46 ENST00000370207.4
coagulation factor III, tissue factor
chr2_+_232633551 0.46 ENST00000264059.8
EF-hand domain family member D1
chr11_+_27040725 0.45 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr19_-_11236497 0.45 ENST00000587656.5
dedicator of cytokinesis 6
chr1_-_109389886 0.43 ENST00000493736.5
sortilin 1
chr9_+_35910076 0.43 ENST00000636776.1
small regulatory polypeptide of amino acid response
chr17_+_78214186 0.43 ENST00000301633.8
ENST00000350051.8
ENST00000374948.6
ENST00000590449.1
baculoviral IAP repeat containing 5
chr8_+_66493514 0.42 ENST00000521495.5
vexin
chr2_-_68319887 0.42 ENST00000409862.1
ENST00000263655.4
cannabinoid receptor interacting protein 1
chr12_+_50112167 0.41 ENST00000548468.2
ENST00000552815.1
ENST00000550654.1
ENST00000550487.6
ENST00000548985.1
novel transcript, antisense to CERS5
cytochrome c oxidase assembly factor COX14
chr4_+_71062642 0.41 ENST00000649996.1
solute carrier family 4 member 4
chr2_+_227616998 0.41 ENST00000641801.1
small cysteine and glycine repeat containing 4
chr17_-_69150062 0.40 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr12_+_101568350 0.40 ENST00000550514.5
myosin binding protein C1
chr5_+_157180816 0.39 ENST00000422843.8
IL2 inducible T cell kinase
chr8_-_61646807 0.39 ENST00000522919.5
aspartate beta-hydroxylase
chr1_-_93681829 0.39 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr12_+_50112028 0.38 ENST00000317943.6
cytochrome c oxidase assembly factor COX14
chr2_-_157628852 0.38 ENST00000243349.13
activin A receptor type 1C
chr22_+_38468036 0.36 ENST00000409006.3
ENST00000216014.9
KDEL endoplasmic reticulum protein retention receptor 3
chrX_-_151974668 0.36 ENST00000370328.4
gamma-aminobutyric acid type A receptor subunit epsilon
chr8_-_61646863 0.36 ENST00000519678.5
aspartate beta-hydroxylase
chr5_+_77086682 0.35 ENST00000643365.1
ENST00000645183.1
ENST00000645374.1
ENST00000647364.1
ENST00000643848.1
ENST00000643603.1
ENST00000645459.1
ENST00000643269.1
ENST00000503969.6
ENST00000646262.1
ZBED3 antisense RNA 1
phosphodiesterase 8B
chr12_-_10167591 0.35 ENST00000543993.5
ENST00000339968.6
oxidized low density lipoprotein receptor 1
chr11_-_5249836 0.35 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr7_-_100119291 0.34 ENST00000431404.2
TATA-box binding protein associated factor 6
chr9_-_14300231 0.34 ENST00000636735.1
nuclear factor I B
chr8_+_124539097 0.33 ENST00000606244.2
ENST00000276689.8
ENST00000518008.5
ENST00000517367.1
NADH:ubiquinone oxidoreductase subunit B9
chr9_-_22009272 0.32 ENST00000380142.5
ENST00000276925.7
cyclin dependent kinase inhibitor 2B
chrX_+_630789 0.31 ENST00000381575.6
short stature homeobox
chr2_+_203936755 0.31 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr11_+_124012997 0.31 ENST00000641521.1
ENST00000641722.1
olfactory receptor family 10 subfamily G member 4
chr4_+_140343443 0.31 ENST00000338517.8
ENST00000394203.7
ENST00000506322.5
short coiled-coil protein
chr12_+_7789393 0.30 ENST00000229307.9
Nanog homeobox
chr12_-_102197827 0.30 ENST00000329406.5
pro-melanin concentrating hormone
chr12_-_75209814 0.29 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr11_-_17476801 0.29 ENST00000644772.1
ENST00000642271.1
ENST00000684571.1
ENST00000646902.1
ENST00000647015.1
ENST00000302539.9
ENST00000389817.8
ENST00000643260.1
ENST00000683136.1
ATP binding cassette subfamily C member 8
chr1_+_75786246 0.29 ENST00000319942.8
Rab geranylgeranyltransferase subunit beta
chr17_-_33293247 0.28 ENST00000225823.7
acid sensing ion channel subunit 2
chr15_-_56465130 0.28 ENST00000260453.4
meiosis specific nuclear structural 1
chr4_-_122456725 0.28 ENST00000226730.5
interleukin 2
chr17_+_78231310 0.27 ENST00000374946.7
ENST00000421688.5
ENST00000586400.5
transmembrane protein 235
chr12_+_25052732 0.27 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr12_+_59664677 0.26 ENST00000548610.5
solute carrier family 16 member 7
chr19_-_43754901 0.26 ENST00000270066.11
ENST00000601170.5
SMG9 nonsense mediated mRNA decay factor
chr12_+_56996151 0.26 ENST00000556850.1
G protein-coupled receptor 182
chr17_-_7204502 0.26 ENST00000486626.8
ENST00000648263.1
discs large MAGUK scaffold protein 4
chr11_-_40293102 0.25 ENST00000527150.5
leucine rich repeat containing 4C
chr7_+_142345412 0.25 ENST00000390392.3
T cell receptor beta variable 4-2
chr13_-_51845169 0.25 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr2_-_157628727 0.25 ENST00000335450.7
ENST00000348328.9
activin A receptor type 1C
chr12_-_6493295 0.24 ENST00000540949.1
mitochondrial ribosomal protein L51
chr11_+_75562056 0.24 ENST00000533603.5
serpin family H member 1
chr6_-_32666648 0.24 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr17_-_78782257 0.24 ENST00000591455.5
ENST00000446868.7
ENST00000361101.8
ENST00000589296.5
cytohesin 1
chr3_+_173584433 0.24 ENST00000361589.8
neuroligin 1
chr7_-_99466148 0.23 ENST00000394186.3
ENST00000359832.8
ENST00000449683.5
ENST00000292475.8
ENST00000488775.5
ENST00000523680.1
ENST00000430982.1
ENST00000413834.5
ATP synthase membrane subunit f
pentatricopeptide repeat domain 1
ATP5MF-PTCD1 readthrough
chr5_-_181261078 0.23 ENST00000611618.1
tripartite motif containing 52
chr14_+_24070837 0.23 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr5_+_43602648 0.23 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr8_+_103298836 0.23 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr11_-_132943092 0.23 ENST00000612177.4
ENST00000541867.5
opioid binding protein/cell adhesion molecule like
chr12_+_49265071 0.22 ENST00000549183.1
ENST00000639419.1
ENST00000301072.11
tubulin alpha 1c
chr3_-_179266971 0.22 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr1_+_75786214 0.22 ENST00000370826.3
Rab geranylgeranyltransferase subunit beta
chrM_+_8489 0.22 ENST00000361899.2
mitochondrially encoded ATP synthase membrane subunit 6
chr8_+_97887903 0.22 ENST00000520016.5
matrilin 2
chr4_+_89894846 0.22 ENST00000264790.7
multimerin 1
chr16_+_28863946 0.21 ENST00000395532.8
SH2B adaptor protein 1
chrX_+_116436599 0.21 ENST00000598581.3
solute carrier family 6 member 14
chr16_+_58392391 0.20 ENST00000426538.6
ENST00000328514.11
GINS complex subunit 3
chr6_-_2744126 0.20 ENST00000647417.1
myosin light chain kinase family member 4
chr22_+_29438583 0.20 ENST00000354373.2
ret finger protein like 1
chr17_-_7208325 0.20 ENST00000650120.1
ENST00000648760.1
discs large MAGUK scaffold protein 4
chr1_+_151060357 0.20 ENST00000368921.5
MLLT11 transcription factor 7 cofactor
chr17_+_78214286 0.20 ENST00000592734.5
ENST00000587746.5
baculoviral IAP repeat containing 5
chr12_+_25052512 0.20 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr12_-_10167657 0.20 ENST00000538745.5
oxidized low density lipoprotein receptor 1
chr7_+_100219236 0.19 ENST00000317271.2
PVR related immunoglobulin domain containing
chr1_+_32205657 0.19 ENST00000291358.11
ENST00000537469.2
IQ motif containing C
chrX_-_48919015 0.19 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr5_+_43603163 0.19 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr16_-_75267988 0.19 ENST00000393422.6
BCAR1 scaffold protein, Cas family member
chrX_+_123960859 0.19 ENST00000458700.5
stromal antigen 2
chr6_+_125203639 0.18 ENST00000392482.6
TPD52 like 1
chr22_+_38057200 0.18 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr9_+_93289187 0.18 ENST00000453718.2
WNK lysine deficient protein kinase 2
chr4_+_75556048 0.18 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr6_+_147508645 0.17 ENST00000367474.2
sterile alpha motif domain containing 5
chr15_-_28174423 0.17 ENST00000569772.1
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr9_-_14322320 0.17 ENST00000606230.2
nuclear factor I B
chr5_+_35852695 0.17 ENST00000508941.5
interleukin 7 receptor
chr6_-_31958935 0.16 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr3_-_56468346 0.16 ENST00000288221.11
ELKS/RAB6-interacting/CAST family member 2
chr15_-_34754989 0.16 ENST00000290374.5
gap junction protein delta 2
chr7_-_5959083 0.16 ENST00000539903.5
radial spoke head 10 homolog B
chr10_-_14554141 0.16 ENST00000496330.5
family with sequence similarity 107 member B
chr2_+_135531460 0.16 ENST00000683871.1
ENST00000409478.5
ENST00000264160.8
ENST00000438014.5
R3H domain containing 1
chr8_-_140800535 0.16 ENST00000521986.5
ENST00000523539.5
protein tyrosine kinase 2
chr10_+_122192442 0.16 ENST00000514539.5
transforming acidic coiled-coil containing protein 2
chr2_-_206159509 0.16 ENST00000423725.5
NADH:ubiquinone oxidoreductase core subunit S1
chr11_-_114595750 0.15 ENST00000424261.6
neurexophilin and PC-esterase domain family member 4
chr12_+_25052220 0.15 ENST00000550945.5
inositol 1,4,5-triphosphate receptor associated 2
chr12_+_25052634 0.15 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chrX_+_41689006 0.15 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr5_-_108382080 0.15 ENST00000542267.7
F-box and leucine rich repeat protein 17
chr1_-_66801276 0.15 ENST00000304526.3
insulin like 5
chr12_-_262828 0.15 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr13_-_46390042 0.15 ENST00000389908.7
rubicon like autophagy enhancer
chr12_-_6493718 0.15 ENST00000543959.5
ENST00000543164.5
ENST00000543703.1
ENST00000537701.5
mitochondrial ribosomal protein L51
chr2_-_206159410 0.15 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chr20_+_43514492 0.14 ENST00000373135.8
ENST00000373134.5
L3MBTL histone methyl-lysine binding protein 1
chr12_-_84892120 0.14 ENST00000680379.1
solute carrier family 6 member 15
chr17_-_81683659 0.14 ENST00000574938.5
ENST00000570561.5
ENST00000573392.5
ENST00000576135.5
ENST00000573715.2
ADP ribosylation factor like GTPase 16
chr22_+_31122923 0.14 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr17_+_64507029 0.14 ENST00000553412.5
centrosomal protein 95
chr14_-_24263162 0.13 ENST00000206765.11
ENST00000544573.5
transglutaminase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.5 2.0 GO:0002086 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.4 3.5 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 24.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 0.7 GO:1902598 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.2 0.5 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543)
0.2 1.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.6 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.2 0.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 5.5 GO:0032060 bleb assembly(GO:0032060)
0.2 1.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.5 GO:0034059 response to anoxia(GO:0034059)
0.1 0.6 GO:0016476 regulation of embryonic cell shape(GO:0016476) septin cytoskeleton organization(GO:0032185)
0.1 0.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.7 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 9.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.2 GO:0031104 dendrite regeneration(GO:0031104)
0.1 0.4 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.5 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.7 GO:2001023 regulation of response to drug(GO:2001023)
0.1 0.2 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 1.0 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.9 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.5 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.9 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.9 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.5 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.8 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 1.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 2.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 1.0 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.0 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.6 GO:0044301 climbing fiber(GO:0044301)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 3.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 4.1 GO:0030018 Z disc(GO:0030018)
0.0 5.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 24.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 5.0 GO:0031433 telethonin binding(GO:0031433)
0.2 0.7 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 1.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.6 GO:0038100 nodal binding(GO:0038100)
0.2 1.7 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.6 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.4 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.1 0.7 GO:0015265 urea channel activity(GO:0015265)
0.1 0.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 1.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 12.8 GO:0003823 antigen binding(GO:0003823)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 4.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport