Project
Illumina Body Map 2 (GSE30611)
Navigation
Downloads
Results for NKX2-8
Z-value: 1.13
Motif logo
Transcription factors associated with NKX2-8
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NKX2-8 | hg38_v1_chr14_-_36582593_36582626 | -0.00 | 9.9e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX2-8
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 24.5 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 9.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 5.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 1.4 | 4.2 | GO:1901877 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.4 | 3.5 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.5 | 2.0 | GO:0002086 | diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972) |
| 0.1 | 1.7 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.2 | 1.6 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.0 | 1.6 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 1.5 | GO:0030239 | myofibril assembly(GO:0030239) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 24.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 5.2 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 4.1 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 3.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 2.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.3 | 2.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 1.5 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.1 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 1.1 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 1.1 | GO:0044295 | axonal growth cone(GO:0044295) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 24.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 12.8 | GO:0003823 | antigen binding(GO:0003823) |
| 0.3 | 5.0 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 4.3 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.2 | 1.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.2 | 1.7 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.1 | 1.6 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.1 | 1.4 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.4 | 1.2 | GO:0031780 | corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) |
| 0.1 | 1.1 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.0 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 0.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 0.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 1.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.1 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 1.0 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.9 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 0.9 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.6 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.6 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.6 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 0.5 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |