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Illumina Body Map 2 (GSE30611)

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Results for NKX3-2

Z-value: 0.94

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Transcription factors associated with NKX3-2

Gene Symbol Gene ID Gene Info
ENSG00000109705.8 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX3-2hg38_v1_chr4_-_13544506_13544513-0.105.8e-01Click!

Activity profile of NKX3-2 motif

Sorted Z-values of NKX3-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_22161788 2.91 ENST00000521315.5
ENST00000437090.6
ENST00000679463.1
ENST00000520605.5
ENST00000522109.5
ENST00000524255.5
ENST00000523296.1
surfactant protein C
chr8_+_22161655 2.64 ENST00000318561.7
surfactant protein C
chr14_-_106557465 2.14 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr7_-_120858066 1.94 ENST00000222747.8
tetraspanin 12
chr7_-_99976017 1.94 ENST00000411734.1
ENST00000292401.9
alpha-2-glycoprotein 1, zinc-binding
chr6_-_32763522 1.94 ENST00000435145.6
ENST00000437316.7
major histocompatibility complex, class II, DQ beta 2
chr14_-_106639589 1.90 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr3_+_194136138 1.78 ENST00000232424.4
hes family bHLH transcription factor 1
chr14_-_106579223 1.78 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr5_+_147878703 1.78 ENST00000296694.5
secretoglobin family 3A member 2
chr6_-_30932147 1.77 ENST00000359086.4
surfactant associated 2
chr16_-_1230089 1.71 ENST00000612142.1
ENST00000606293.5
tryptase beta 2
chr7_-_99971845 1.71 ENST00000419575.1
alpha-2-glycoprotein 1, zinc-binding
chr2_+_102311546 1.61 ENST00000233954.6
ENST00000447231.5
interleukin 1 receptor like 1
chr6_-_32763466 1.60 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chr11_-_102530738 1.55 ENST00000260227.5
matrix metallopeptidase 7
chr19_+_16888991 1.55 ENST00000248076.4
F2R like thrombin or trypsin receptor 3
chr14_-_106507476 1.53 ENST00000390621.3
immunoglobulin heavy variable 1-45
chr2_+_102311502 1.48 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr5_+_69415065 1.45 ENST00000647531.1
ENST00000645446.1
ENST00000325631.10
ENST00000454295.6
MARVEL domain containing 2
chr10_+_5048748 1.44 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr11_-_120138104 1.42 ENST00000341846.10
tripartite motif containing 29
chr5_+_79111802 1.39 ENST00000524080.1
ENST00000274353.10
betaine--homocysteine S-methyltransferase
chr4_+_42397473 1.38 ENST00000319234.5
shisa family member 3
chr14_-_106374129 1.30 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr17_+_4498866 1.30 ENST00000329078.8
sphingolipid transporter 2
chr2_-_88861563 1.29 ENST00000624935.3
ENST00000390241.3
novel transcript
immunoglobulin kappa joining 2
chr14_-_106627685 1.28 ENST00000390629.3
immunoglobulin heavy variable 4-59
chr13_-_110242694 1.24 ENST00000648989.1
ENST00000647797.1
ENST00000648966.1
ENST00000649484.1
ENST00000648695.1
ENST00000650115.1
ENST00000650566.1
collagen type IV alpha 1 chain
chr3_-_51974001 1.24 ENST00000489595.6
ENST00000461108.5
ENST00000395008.6
ENST00000361143.10
ENST00000525795.1
ENST00000488257.2
poly(rC) binding protein 4
abhydrolase domain containing 14B
novel transcript
chr10_-_96271508 1.22 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr12_-_50222348 1.15 ENST00000552823.5
ENST00000552909.5
LIM domain and actin binding 1
chr1_-_153544997 1.15 ENST00000368715.5
S100 calcium binding protein A4
chr3_+_132597260 1.13 ENST00000249887.3
atypical chemokine receptor 4
chr10_-_5977492 1.13 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
interleukin 15 receptor subunit alpha
chr10_+_5094405 1.11 ENST00000380554.5
aldo-keto reductase family 1 member C3
chr11_+_60455839 1.09 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr6_-_32589833 1.09 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr7_-_131556602 1.08 ENST00000322985.9
ENST00000378555.8
podocalyxin like
chr12_-_21774688 1.06 ENST00000240662.3
potassium inwardly rectifying channel subfamily J member 8
chr6_-_11382247 1.05 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr5_+_40909490 1.05 ENST00000313164.10
complement C7
chr12_-_21775045 1.04 ENST00000667884.1
potassium inwardly rectifying channel subfamily J member 8
chr16_+_57372481 1.02 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr14_+_22547495 1.00 ENST00000611116.2
T cell receptor alpha constant
chr1_-_149842736 0.98 ENST00000369159.2
H2A clustered histone 18
chr11_-_26572102 0.98 ENST00000455601.6
mucin 15, cell surface associated
chr14_-_105940235 0.98 ENST00000390593.2
immunoglobulin heavy variable 6-1
chr16_+_57372465 0.98 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr8_-_94262308 0.97 ENST00000297596.3
ENST00000396194.6
GTP binding protein overexpressed in skeletal muscle
chr4_+_70637662 0.96 ENST00000472597.1
ENST00000472903.5
enamelin
novel transcript
chr3_+_186996444 0.96 ENST00000676633.1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr14_-_106005574 0.96 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr14_+_61697622 0.96 ENST00000539097.2
hypoxia inducible factor 1 subunit alpha
chrX_-_108438407 0.96 ENST00000334504.12
ENST00000621266.4
ENST00000538570.5
ENST00000394872.6
ENST00000545689.2
collagen type IV alpha 6 chain
chr11_-_5243644 0.96 ENST00000643122.1
hemoglobin subunit delta
chr4_+_155903688 0.95 ENST00000536354.3
tryptophan 2,3-dioxygenase
chr1_-_204213943 0.95 ENST00000308302.4
golgi transport 1A
chr7_+_116210501 0.95 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr10_-_5966327 0.94 ENST00000532039.5
interleukin 15 receptor subunit alpha
chrX_+_106693751 0.94 ENST00000418562.5
ring finger protein 128
chr15_-_43220989 0.94 ENST00000540029.5
ENST00000441366.7
ENST00000648595.1
erythrocyte membrane protein band 4.2
chr19_+_40991274 0.93 ENST00000324071.10
cytochrome P450 family 2 subfamily B member 6
chr11_-_59866478 0.93 ENST00000257264.4
transcobalamin 1
chr14_-_106012390 0.91 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr11_-_76669985 0.90 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr1_-_36482904 0.89 ENST00000373106.6
colony stimulating factor 3 receptor
chr1_-_159925496 0.89 ENST00000368097.9
transgelin 2
chr7_+_116222804 0.88 ENST00000393481.6
testin LIM domain protein
chr9_-_92482499 0.88 ENST00000375544.7
asporin
chr12_+_49961864 0.88 ENST00000293599.7
aquaporin 5
chr17_+_18952158 0.87 ENST00000395647.6
ENST00000417251.6
ENST00000395645.4
solute carrier family 5 member 10
chr11_-_26572254 0.87 ENST00000529533.6
mucin 15, cell surface associated
chr12_+_80099535 0.85 ENST00000646859.1
ENST00000547103.7
otogelin like
chr12_-_14929116 0.85 ENST00000540097.1
endoplasmic reticulum protein 27
chr9_-_129178247 0.84 ENST00000372491.4
immediate early response 5 like
chr4_+_168711416 0.83 ENST00000649826.1
palladin, cytoskeletal associated protein
chr1_+_81800906 0.83 ENST00000674393.1
ENST00000674208.1
adhesion G protein-coupled receptor L2
chr14_-_106324743 0.83 ENST00000390612.3
immunoglobulin heavy variable 4-28
chr15_-_90233902 0.81 ENST00000328649.11
ENST00000650306.1
calcium and integrin binding 1
chr11_-_74697694 0.81 ENST00000529912.5
chordin like 2
chrX_+_106693838 0.81 ENST00000324342.7
ring finger protein 128
chr19_-_46784905 0.81 ENST00000594991.5
solute carrier family 1 member 5
chr11_-_128867364 0.79 ENST00000440599.6
ENST00000324036.7
potassium inwardly rectifying channel subfamily J member 1
chr11_-_128867268 0.79 ENST00000392665.6
ENST00000392666.6
potassium inwardly rectifying channel subfamily J member 1
chr19_+_41877267 0.78 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr10_+_8053604 0.78 ENST00000481743.2
GATA binding protein 3
chr12_-_121858849 0.77 ENST00000289004.8
4-hydroxyphenylpyruvate dioxygenase
chr12_-_21775581 0.77 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr17_-_48430205 0.76 ENST00000336915.11
ENST00000584924.5
src kinase associated phosphoprotein 1
chr9_-_22009272 0.76 ENST00000380142.5
ENST00000276925.7
cyclin dependent kinase inhibitor 2B
chr2_+_79120474 0.76 ENST00000233735.2
regenerating family member 1 alpha
chr1_+_149851053 0.75 ENST00000607355.2
H2A clustered histone 19
chr9_+_113349514 0.75 ENST00000374183.5
B-box and SPRY domain containing
chr14_+_20688756 0.75 ENST00000397990.5
ENST00000555597.1
angiogenin
ribonuclease A family member 4
chr10_-_7666955 0.74 ENST00000397146.7
ENST00000397145.6
inter-alpha-trypsin inhibitor heavy chain 5
chr17_+_70075215 0.73 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr9_-_127847117 0.72 ENST00000480266.5
endoglin
chr4_+_147480917 0.72 ENST00000324300.10
ENST00000358556.8
ENST00000511804.5
ENST00000648866.1
endothelin receptor type A
chr16_+_57372525 0.71 ENST00000564948.1
C-X3-C motif chemokine ligand 1
chr9_-_92482350 0.71 ENST00000375543.2
asporin
chr10_-_47484081 0.71 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr16_-_88785210 0.71 ENST00000301015.14
piezo type mechanosensitive ion channel component 1
chr13_+_110424798 0.69 ENST00000619688.2
collagen type IV alpha 2 chain
chr15_+_81182579 0.69 ENST00000302987.9
interleukin 16
chr8_-_48921419 0.68 ENST00000020945.4
snail family transcriptional repressor 2
chr5_-_176899332 0.68 ENST00000292432.10
hexokinase 3
chr6_-_31729785 0.67 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr20_+_43916142 0.67 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr6_-_31729478 0.67 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr6_-_138572523 0.67 ENST00000427025.6
NHS like 1
chr11_+_34621109 0.67 ENST00000450654.6
ETS homologous factor
chr6_-_47042306 0.66 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr7_+_80638633 0.66 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr1_-_24930263 0.65 ENST00000308873.11
RUNX family transcription factor 3
chr12_-_50222694 0.65 ENST00000552783.5
LIM domain and actin binding 1
chr4_+_88007624 0.65 ENST00000237596.7
polycystin 2, transient receptor potential cation channel
chr11_+_35201083 0.65 ENST00000526553.6
CD44 molecule (Indian blood group)
chr3_-_149670877 0.64 ENST00000475579.1
WW domain containing transcription regulator 1
chr11_-_120123026 0.64 ENST00000533302.5
tripartite motif containing 29
chr1_+_86424154 0.64 ENST00000370565.5
chloride channel accessory 2
chr14_-_106622837 0.63 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr2_+_176151543 0.62 ENST00000306324.4
homeobox D4
chr5_-_150412743 0.62 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr16_+_83953232 0.62 ENST00000565123.5
ENST00000393306.6
oxidative stress induced growth inhibitor 1
chr9_+_109780312 0.62 ENST00000483909.5
ENST00000413420.5
ENST00000302798.7
PALM2 and AKAP2 fusion
chr3_-_100832300 0.62 ENST00000478235.5
ENST00000471901.5
ABI family member 3 binding protein
chr18_+_44680093 0.62 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr6_-_31730198 0.62 ENST00000375787.6
dimethylarginine dimethylaminohydrolase 2
chr7_+_128937917 0.62 ENST00000357234.10
ENST00000613821.4
ENST00000477535.5
ENST00000479582.5
ENST00000464557.5
ENST00000402030.6
interferon regulatory factor 5
chr7_+_150450623 0.61 ENST00000307271.4
GTPase, IMAP family member 8
chr11_-_107018462 0.61 ENST00000526355.7
guanylate cyclase 1 soluble subunit alpha 2
chr12_+_6385119 0.61 ENST00000541102.1
lymphotoxin beta receptor
chr3_-_100840109 0.60 ENST00000533795.5
ABI family member 3 binding protein
chr11_+_34621065 0.60 ENST00000257831.8
ETS homologous factor
chr14_-_106108453 0.60 ENST00000632950.2
immunoglobulin heavy variable 5-10-1
chr19_+_852295 0.58 ENST00000263621.2
elastase, neutrophil expressed
chr1_-_182604379 0.58 ENST00000367558.6
regulator of G protein signaling 16
chr2_+_85584402 0.58 ENST00000306384.5
vesicle associated membrane protein 5
chr7_+_76510528 0.58 ENST00000334348.8
uroplakin 3B
chr4_+_147481085 0.57 ENST00000651419.1
endothelin receptor type A
chr9_-_92482461 0.57 ENST00000651738.1
asporin
chr4_+_108650644 0.56 ENST00000512478.2
oligosaccharyltransferase complex non-catalytic subunit
chr5_+_56815534 0.55 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr1_+_162381703 0.54 ENST00000458626.4
chromosome 1 open reading frame 226
chr7_+_80638662 0.54 ENST00000394788.7
CD36 molecule
chr17_+_7579491 0.53 ENST00000380498.10
ENST00000584502.1
ENST00000250092.11
CD68 molecule
chr2_-_27071628 0.53 ENST00000447619.5
ENST00000429985.1
ENST00000456793.2
oligosaccharyltransferase complex subunit 4, non-catalytic
chr2_-_88860913 0.52 ENST00000390239.2
immunoglobulin kappa joining 4
chr14_-_106875069 0.52 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr15_-_90234046 0.52 ENST00000612800.1
calcium and integrin binding 1
chr5_+_76609091 0.51 ENST00000514001.5
ENST00000396234.7
ENST00000509074.5
ENST00000502745.5
IQ motif containing GTPase activating protein 2
chr17_-_76141240 0.51 ENST00000322957.7
forkhead box J1
chr11_-_26572130 0.50 ENST00000527569.1
mucin 15, cell surface associated
chr15_-_53733103 0.50 ENST00000559418.5
WD repeat domain 72
chr17_+_70075317 0.50 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chr1_-_173917281 0.50 ENST00000367698.4
serpin family C member 1
chr18_+_44680875 0.49 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr3_-_42875871 0.49 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr2_+_237486391 0.49 ENST00000429898.5
ENST00000410032.5
melanophilin
chr14_+_20999255 0.49 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr4_-_118352967 0.49 ENST00000296498.3
serine protease 12
chr8_-_48921735 0.49 ENST00000396822.6
snail family transcriptional repressor 2
chr12_-_57767057 0.48 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr11_-_120138031 0.47 ENST00000627238.1
tripartite motif containing 29
chr6_-_32853813 0.47 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr19_-_49325181 0.47 ENST00000454748.7
ENST00000335875.9
ENST00000598828.1
solute carrier family 6 member 16
chr18_+_23884773 0.46 ENST00000586751.5
laminin subunit alpha 3
chr1_-_8015633 0.45 ENST00000467067.1
ERBB receptor feedback inhibitor 1
chr5_+_69415382 0.45 ENST00000512803.5
MARVEL domain containing 2
chr17_-_81656532 0.45 ENST00000331056.10
phosphodiesterase 6G
chr1_+_23959109 0.45 ENST00000471915.5
proline rich nuclear receptor coactivator 2
chr5_-_1345084 0.45 ENST00000320895.10
CLPTM1 like
chr19_-_46023046 0.44 ENST00000008938.5
peptidoglycan recognition protein 1
chr11_+_13962676 0.43 ENST00000576479.4
spondin 1
chr2_-_38751350 0.43 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
serine and arginine rich splicing factor 7
chr1_-_204494752 0.43 ENST00000684373.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_+_93741591 0.43 ENST00000528288.5
ENST00000617482.4
ENST00000540113.5
chromosome 11 open reading frame 54
chr12_+_49741544 0.43 ENST00000549966.5
ENST00000547832.5
ENST00000547187.5
ENST00000548894.5
ENST00000546914.5
ENST00000552699.5
ENST00000267115.10
transmembrane BAX inhibitor motif containing 6
chr3_-_146544578 0.43 ENST00000342435.9
ENST00000448787.6
phospholipid scramblase 1
chr4_+_48016764 0.42 ENST00000295461.10
NIPA like domain containing 1
chr22_-_37244417 0.42 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr2_-_70553638 0.42 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr6_-_116060859 0.41 ENST00000606080.2
fyn related Src family tyrosine kinase
chr17_-_45410414 0.41 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr11_+_63938971 0.41 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr10_+_100998676 0.41 ENST00000481129.1
leucine zipper tumor suppressor 2
chr4_+_17577487 0.41 ENST00000606142.5
leucine aminopeptidase 3
chr9_+_35161951 0.40 ENST00000617908.4
ENST00000619578.4
unc-13 homolog B
chr5_+_111071710 0.40 ENST00000344895.4
thymic stromal lymphopoietin
chr7_+_142615710 0.40 ENST00000611520.1
T cell receptor beta variable 18
chr1_+_93079264 0.40 ENST00000370298.9
ENST00000370303.4
metal response element binding transcription factor 2
chr3_+_122184233 0.40 ENST00000638421.1
ENST00000498619.4
calcium sensing receptor
chr9_+_35162000 0.39 ENST00000396787.5
ENST00000378495.7
ENST00000635942.1
ENST00000378496.8
unc-13 homolog B
chr3_+_189631373 0.39 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr2_+_157257687 0.39 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr20_-_2840623 0.39 ENST00000360652.7
ENST00000448755.5
PC-esterase domain containing 1A
chr21_-_34887148 0.39 ENST00000399240.5
RUNX family transcription factor 1
chr19_+_40807112 0.38 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia inducible factor 2
chr3_-_146544701 0.38 ENST00000487389.5
phospholipid scramblase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX3-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0051041 positive regulation of calcium-independent cell-cell adhesion(GO:0051041)
0.9 2.6 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.6 1.8 GO:0045608 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.5 1.4 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.4 1.8 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.4 1.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 3.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.3 1.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 1.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.3 1.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.3 1.0 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 1.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.3 0.8 GO:0046967 cytosol to ER transport(GO:0046967)
0.3 2.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 0.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 1.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 0.7 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.2 0.7 GO:0071464 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) cellular response to hydrostatic pressure(GO:0071464)
0.2 0.6 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 0.8 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 0.8 GO:2000701 regulation of cell proliferation involved in mesonephros development(GO:2000606) negative regulation of cell proliferation involved in mesonephros development(GO:2000607) fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000699) glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000701) regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000702) negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation(GO:2000703) regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000733) negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation(GO:2000734)
0.2 1.3 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.2 0.7 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.2 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.5 GO:0070564 positive regulation of vitamin D receptor signaling pathway(GO:0070564)
0.2 1.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.2 13.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.7 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 1.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.7 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.6 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 2.0 GO:0000052 citrulline metabolic process(GO:0000052)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 2.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 1.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 3.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.7 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 1.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 1.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 1.2 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 1.9 GO:0010842 retina layer formation(GO:0010842)
0.0 1.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 1.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 4.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 1.0 GO:0015671 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.6 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 1.2 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.2 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.6 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 4.0 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 2.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 1.8 GO:0031529 ruffle organization(GO:0031529)
0.0 0.5 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 2.1 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.6 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) negative regulation of long term synaptic depression(GO:1900453) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.1 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.5 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 2.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.4 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.1 GO:0019682 fructose catabolic process(GO:0006001) glyceraldehyde-3-phosphate metabolic process(GO:0019682) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.3 5.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.7 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.7 GO:0016590 ACF complex(GO:0016590)
0.2 12.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 2.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 2.1 GO:0061689 tricellular tight junction(GO:0061689)
0.2 0.8 GO:0019814 immunoglobulin complex(GO:0019814)
0.1 0.7 GO:0002133 polycystin complex(GO:0002133)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.8 GO:0044305 early phagosome(GO:0032009) calyx of Held(GO:0044305)
0.1 0.4 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 2.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.6 GO:0032433 filopodium tip(GO:0032433)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.9 2.7 GO:0031737 CX3C chemokine receptor binding(GO:0031737)
0.9 2.6 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.5 2.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.3 1.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 2.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 3.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 1.6 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 4.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 12.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 0.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 1.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 1.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.0 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.8 GO:0023029 MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.1 1.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.7 GO:0005534 galactose binding(GO:0005534)
0.1 0.8 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 2.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.6 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 2.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.9 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.9 GO:0015250 water channel activity(GO:0015250)
0.0 1.0 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.4 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.6 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 1.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 4.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 3.3 GO:0003823 antigen binding(GO:0003823)
0.0 3.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0030553 cGMP binding(GO:0030553)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0018479 androgen binding(GO:0005497) benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 3.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 9.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 6.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 2.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane