ISMARA results: NKX6-2

Project

Illumina Body Map 2 (GSE30611)

Navigation

Downloads

Results for NKX6-2

Z-value: 1.58

Motif logo

Transcription factors associated with NKX6-2

Gene Symbol	Gene ID	Gene Info
NKX6-2 Ensembl NCBI GeneCards UniProt	ENSG00000148826.9	NK6 homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX6-2	hg38_v1_chr10_-_132786146_132786149	0.86	2.2e-10	Click!

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_101594849 Show fit	8.76	ENST00000547405.5 ENST00000452455.6 ENST00000392934.7 ENST00000547509.5 ENST00000361685.6 ENST00000549145.5 ENST00000361466.7 ENST00000553190.5 ENST00000545503.6 ENST00000536007.5 ENST00000541119.5 ENST00000551300.5 ENST00000550270.1	MYBPC1 Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein C1
chr8_+_24440930 Show fit	7.46	ENST00000441335.6 ENST00000175238.10 ENST00000380789.5	ADAM7 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase domain 7
chr4_+_41256921 Show fit	6.88	ENST00000284440.9 ENST00000508768.5 ENST00000512788.1	UCHL1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin C-terminal hydrolase L1
chr3_+_39467598 Show fit	6.11	ENST00000428261.5 ENST00000420739.5 ENST00000415443.5 ENST00000447324.5 ENST00000383754.7	MOBP Ensembl NCBI GeneCards UniProt Show fit	myelin associated oligodendrocyte basic protein
chr2_-_216695540 Show fit	5.99	ENST00000233813.5	IGFBP5 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 5
chrX_-_81201886 Show fit	5.48	ENST00000451455.1 ENST00000358130.7 ENST00000436386.5	HMGN5 Ensembl NCBI GeneCards UniProt Show fit	high mobility group nucleosome binding domain 5
chr6_+_12290353 Show fit	5.33	ENST00000379375.6	EDN1 Ensembl NCBI GeneCards UniProt Show fit	endothelin 1
chr1_+_110451132 Show fit	5.22	ENST00000271331.4	PROK1 Ensembl NCBI GeneCards UniProt Show fit	prokineticin 1
chr3_+_39467672 Show fit	4.96	ENST00000436143.6 ENST00000441980.6 ENST00000682069.1 ENST00000311042.10	MOBP Ensembl NCBI GeneCards UniProt Show fit	myelin associated oligodendrocyte basic protein
chr17_-_44915486 Show fit	4.85	ENST00000638281.1 ENST00000588316.1 ENST00000588735.3 ENST00000639277.1 ENST00000253408.11 ENST00000435360.8 ENST00000586793.6 ENST00000588037.1 ENST00000592320.6	GFAP Ensembl NCBI GeneCards UniProt Show fit	glial fibrillary acidic protein
chrX_+_103585478 Show fit	4.60	ENST00000468024.5 ENST00000415568.2 ENST00000472484.6 ENST00000613326.4 ENST00000490644.5 ENST00000459722.1 ENST00000472745.1 ENST00000494801.5 ENST00000434216.2	TCEAL4 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A like 4
chr2_-_216694794 Show fit	4.54	ENST00000449583.1	IGFBP5 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor binding protein 5
chr4_-_184217854 Show fit	4.40	ENST00000296741.7	ENPP6 Ensembl NCBI GeneCards UniProt Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 6
chr7_-_137343752 Show fit	4.39	ENST00000393083.2	PTN Ensembl NCBI GeneCards UniProt Show fit	pleiotrophin
chr13_-_35855758 Show fit	4.30	ENST00000615680.4	DCLK1 Ensembl NCBI GeneCards UniProt Show fit	doublecortin like kinase 1
chr3_-_98522514 Show fit	4.23	ENST00000503004.5 ENST00000506575.1 ENST00000513452.5 ENST00000515620.5	CLDND1 Ensembl NCBI GeneCards UniProt Show fit	claudin domain containing 1
chr4_+_168497066 Show fit	4.18	ENST00000261509.10	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr14_-_26597430 Show fit	3.74	ENST00000344429.9 ENST00000574031.1 ENST00000465357.6 ENST00000547619.5	NOVA1 Ensembl NCBI GeneCards UniProt Show fit	NOVA alternative splicing regulator 1
chr11_-_5227063 Show fit	3.68	ENST00000335295.4 ENST00000485743.1 ENST00000647020.1	HBB Ensembl NCBI GeneCards UniProt Show fit	hemoglobin subunit beta
chr2_-_174847250 Show fit	3.65	ENST00000409089.7	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr2_-_174847765 Show fit	3.61	ENST00000443238.6	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr5_+_95731300 Show fit	3.58	ENST00000379982.8	RHOBTB3 Ensembl NCBI GeneCards UniProt Show fit	Rho related BTB domain containing 3
chr2_+_209579598 Show fit	3.57	ENST00000445941.5 ENST00000673860.1	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr2_-_174847525 Show fit	3.57	ENST00000295497.12 ENST00000652036.1 ENST00000444394.6 ENST00000650731.1	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr3_-_79767987 Show fit	3.49	ENST00000464233.6	ROBO1 Ensembl NCBI GeneCards UniProt Show fit	roundabout guidance receptor 1
chr2_+_232662733 Show fit	3.35	ENST00000410095.5 ENST00000611312.1	EFHD1 Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family member D1
chr18_+_34710249 Show fit	3.32	ENST00000680346.1 ENST00000348997.9 ENST00000681274.1 ENST00000680822.1 ENST00000680767.2 ENST00000597599.5 ENST00000444659.6	DTNA Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr4_+_168497044 Show fit	3.31	ENST00000505667.6	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr1_-_109393197 Show fit	3.31	ENST00000538502.5 ENST00000482236.5	SORT1 Ensembl NCBI GeneCards UniProt Show fit	sortilin 1
chr4_-_86453075 Show fit	3.19	ENST00000641384.1 ENST00000642009.1 ENST00000641274.1 ENST00000641629.1 ENST00000641718.1 ENST00000641782.1 ENST00000511328.5 ENST00000503911.5 ENST00000641862.1 ENST00000640445.1 ENST00000641675.1 ENST00000361569.8 ENST00000639989.2 ENST00000641120.1 ENST00000642023.1 ENST00000641902.1 ENST00000641016.1 ENST00000509464.7 ENST00000638946.2 ENST00000395160.9 ENST00000512017.7 ENST00000639972.2	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr1_+_170663134 Show fit	3.16	ENST00000367760.7	PRRX1 Ensembl NCBI GeneCards UniProt Show fit	paired related homeobox 1
chr2_+_108378176 Show fit	3.15	ENST00000409309.3	SULT1C4 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1C member 4
chr2_+_209579399 Show fit	3.13	ENST00000360351.8	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr9_-_23826231 Show fit	3.05	ENST00000397312.7	ELAVL2 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 2
chr8_-_81483226 Show fit	3.04	ENST00000256104.5	FABP4 Ensembl NCBI GeneCards UniProt Show fit	fatty acid binding protein 4
chr12_+_6914571 Show fit	3.03	ENST00000229277.6 ENST00000538763.5 ENST00000545045.6	ENO2 Ensembl NCBI GeneCards UniProt Show fit	enolase 2
chrX_-_103832204 Show fit	3.00	ENST00000674363.1 ENST00000674162.1 ENST00000674338.1 ENST00000674274.1 ENST00000674271.1 ENST00000674265.1 ENST00000674212.1 ENST00000674255.1 ENST00000674342.1 ENST00000674430.1 ENST00000243298.3	ENSG00000288597.1 Ensembl NCBI GeneCards UniProt Show fit RAB9B Ensembl NCBI GeneCards UniProt Show fit	novel transcript RAB9B, member RAS oncogene family
chr2_-_210477562 Show fit	2.99	ENST00000448951.5	LANCL1 Ensembl NCBI GeneCards UniProt Show fit	LanC like 1
chr1_-_243163310 Show fit	2.87	ENST00000492145.1 ENST00000490813.5 ENST00000464936.5	CEP170 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 170
chr4_+_87975667 Show fit	2.73	ENST00000237623.11 ENST00000682655.1 ENST00000508233.6 ENST00000360804.4 ENST00000395080.8	SPP1 Ensembl NCBI GeneCards UniProt Show fit	secreted phosphoprotein 1
chrX_+_136148440 Show fit	2.71	ENST00000627383.2 ENST00000630084.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr9_+_127264740 Show fit	2.70	ENST00000373387.9	GARNL3 Ensembl NCBI GeneCards UniProt Show fit	GTPase activating Rap/RanGAP domain like 3
chr18_-_12656716 Show fit	2.68	ENST00000462226.1 ENST00000497844.6 ENST00000309836.9 ENST00000453447.6	SPIRE1 Ensembl NCBI GeneCards UniProt Show fit	spire type actin nucleation factor 1
chr3_+_319683 Show fit	2.67	ENST00000620033.4	CHL1 Ensembl NCBI GeneCards UniProt Show fit	cell adhesion molecule L1 like
chr12_+_40742342 Show fit	2.62	ENST00000548005.5 ENST00000552248.5	CNTN1 Ensembl NCBI GeneCards UniProt Show fit	contactin 1
chr2_-_73293538 Show fit	2.61	ENST00000436467.4 ENST00000545030.1	EGR4 Ensembl NCBI GeneCards UniProt Show fit	early growth response 4
chr5_+_161848314 Show fit	2.59	ENST00000437025.6	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr11_+_122882683 Show fit	2.52	ENST00000307257.10 ENST00000227349.7	JHY Ensembl NCBI GeneCards UniProt Show fit	junctional cadherin complex regulator
chr13_+_53028806 Show fit	2.51	ENST00000219022.3	OLFM4 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 4
chr2_+_108377947 Show fit	2.48	ENST00000272452.7	SULT1C4 Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1C member 4
chr15_-_48963912 Show fit	2.48	ENST00000332408.9	SHC4 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 4
chr5_+_145936554 Show fit	2.48	ENST00000359120.9	SH3RF2 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing ring finger 2
chr15_+_49423233 Show fit	2.47	ENST00000560270.1 ENST00000267843.9 ENST00000560979.1	FGF7 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 7
chrX_+_10156960 Show fit	2.40	ENST00000380833.9	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr4_-_89838289 Show fit	2.38	ENST00000336904.7	SNCA Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha
chr3_+_159839847 Show fit	2.37	ENST00000445224.6	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr4_-_139280179 Show fit	2.36	ENST00000398955.2	MGARP Ensembl NCBI GeneCards UniProt Show fit	mitochondria localized glutamic acid rich protein
chr16_+_56191476 Show fit	2.33	ENST00000262493.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr6_-_130956371 Show fit	2.33	ENST00000639623.1 ENST00000525193.5 ENST00000527659.5	EPB41L2 Ensembl NCBI GeneCards UniProt Show fit	erythrocyte membrane protein band 4.1 like 2
chr1_+_85062304 Show fit	2.28	ENST00000326813.12 ENST00000528899.5 ENST00000294664.11	DNAI3 Ensembl NCBI GeneCards UniProt Show fit	dynein axonemal intermediate chain 3
chr13_-_44474296 Show fit	2.26	ENST00000611198.4	TSC22D1 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 1
chr1_+_114854858 Show fit	2.24	ENST00000369522.8 ENST00000455987.5 ENST00000618516.4 ENST00000613524.4	SYCP1 Ensembl NCBI GeneCards UniProt Show fit	synaptonemal complex protein 1
chr14_-_75063990 Show fit	2.22	ENST00000555135.1 ENST00000357971.7 ENST00000553302.1 ENST00000238618.8 ENST00000555694.5	ACYP1 Ensembl NCBI GeneCards UniProt Show fit	acylphosphatase 1
chr9_+_79571956 Show fit	2.19	ENST00000376552.8	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr3_+_16174628 Show fit	2.19	ENST00000339732.10	GALNT15 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 15
chr1_+_107139996 Show fit	2.19	ENST00000370073.6 ENST00000370074.8	NTNG1 Ensembl NCBI GeneCards UniProt Show fit	netrin G1
chrX_+_55717733 Show fit	2.15	ENST00000414239.5 ENST00000374941.9	RRAGB Ensembl NCBI GeneCards UniProt Show fit	Ras related GTP binding B
chr1_-_110391041 Show fit	2.14	ENST00000369781.8 ENST00000437429.6 ENST00000541986.5	SLC16A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 4
chr1_-_247723764 Show fit	2.13	ENST00000419891.1	ENSG00000239395.2 Ensembl NCBI GeneCards UniProt Show fit	novel protein
chr21_-_35049327 Show fit	2.11	ENST00000300305.7	RUNX1 Ensembl NCBI GeneCards UniProt Show fit	RUNX family transcription factor 1
chr9_-_28670285 Show fit	2.09	ENST00000379992.6 ENST00000308675.5 ENST00000613945.3	LINGO2 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat and Ig domain containing 2
chr1_+_244352627 Show fit	2.08	ENST00000366537.5 ENST00000308105.5	C1orf100 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 100
chr14_-_59630806 Show fit	2.04	ENST00000342503.8	RTN1 Ensembl NCBI GeneCards UniProt Show fit	reticulon 1
chr11_-_7706469 Show fit	2.01	ENST00000533663.6	OVCH2 Ensembl NCBI GeneCards UniProt Show fit	ovochymase 2
chr18_-_500692 Show fit	2.01	ENST00000400256.5	COLEC12 Ensembl NCBI GeneCards UniProt Show fit	collectin subfamily member 12
chr14_-_26598025 Show fit	1.99	ENST00000539517.7	NOVA1 Ensembl NCBI GeneCards UniProt Show fit	NOVA alternative splicing regulator 1
chrX_+_55717796 Show fit	1.97	ENST00000262850.7	RRAGB Ensembl NCBI GeneCards UniProt Show fit	Ras related GTP binding B
chr7_-_108240049 Show fit	1.97	ENST00000379022.8	NRCAM Ensembl NCBI GeneCards UniProt Show fit	neuronal cell adhesion molecule
chrX_+_103585615 Show fit	1.94	ENST00000425011.1	TCEAL4 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A like 4
chr9_-_23826299 Show fit	1.94	ENST00000380117.5	ELAVL2 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 2
chrX_+_154304923 Show fit	1.93	ENST00000426989.5 ENST00000426203.5 ENST00000369912.2	TKTL1 Ensembl NCBI GeneCards UniProt Show fit	transketolase like 1
chr6_-_79537423 Show fit	1.93	ENST00000369846.9 ENST00000392959.5 ENST00000467898.3	LCA5 Ensembl NCBI GeneCards UniProt Show fit	lebercilin LCA5
chr1_-_110390989 Show fit	1.91	ENST00000369779.9 ENST00000472422.6	SLC16A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 4
chr17_-_69060906 Show fit	1.87	ENST00000495634.5 ENST00000453985.6 ENST00000340001.9 ENST00000585714.1	ABCA9 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 9
chr17_+_29941605 Show fit	1.86	ENST00000394835.7	EFCAB5 Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 5
chr7_+_120273129 Show fit	1.81	ENST00000331113.9	KCND2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily D member 2
chr3_+_16174703 Show fit	1.80	ENST00000437509.3	GALNT15 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 15
chr1_+_86547070 Show fit	1.77	ENST00000370563.3	CLCA4 Ensembl NCBI GeneCards UniProt Show fit	chloride channel accessory 4
chr4_+_54229261 Show fit	1.77	ENST00000508170.5 ENST00000512143.1 ENST00000257290.10	PDGFRA Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor receptor alpha
chr14_+_88385643 Show fit	1.75	ENST00000393545.9 ENST00000356583.9 ENST00000555401.5 ENST00000553885.5	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr6_-_56851888 Show fit	1.73	ENST00000312431.10 ENST00000520645.5	DST Ensembl NCBI GeneCards UniProt Show fit	dystonin
chr1_-_190477854 Show fit	1.73	ENST00000367462.5	BRINP3 Ensembl NCBI GeneCards UniProt Show fit	BMP/retinoic acid inducible neural specific 3
chr2_+_209579429 Show fit	1.72	ENST00000361559.8	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chrX_-_135120526 Show fit	1.69	ENST00000423661.1	ETDB Ensembl NCBI GeneCards UniProt Show fit	embryonic testis differentiation homolog B
chr21_-_35049238 Show fit	1.69	ENST00000416754.1 ENST00000437180.5 ENST00000455571.5 ENST00000675419.1	RUNX1 Ensembl NCBI GeneCards UniProt Show fit	RUNX family transcription factor 1
chrX_+_34942790 Show fit	1.68	ENST00000329357.6	FAM47B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 47 member B
chr18_-_36798482 Show fit	1.64	ENST00000590258.2	TPGS2 Ensembl NCBI GeneCards UniProt Show fit	tubulin polyglutamylase complex subunit 2
chr1_-_247724043 Show fit	1.64	ENST00000366485.1	OR14A2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 14 subfamily A member 2
chr5_+_102808057 Show fit	1.63	ENST00000684043.1 ENST00000682407.1	PAM Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr18_-_3219849 Show fit	1.61	ENST00000261606.11	MYOM1 Ensembl NCBI GeneCards UniProt Show fit	myomesin 1
chr5_-_20575850 Show fit	1.58	ENST00000507958.5	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18
chr8_-_42501224 Show fit	1.57	ENST00000520262.6 ENST00000517366.1	SLC20A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 member 2
chr8_+_26293112 Show fit	1.57	ENST00000523925.5 ENST00000315985.7	PPP2R2A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Balpha
chr16_+_14708944 Show fit	1.56	ENST00000526520.5 ENST00000531598.6	NPIPA3 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member A3
chr1_+_77918128 Show fit	1.56	ENST00000342754.5	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin F-actin binding protein
chr18_-_3219961 Show fit	1.53	ENST00000356443.9	MYOM1 Ensembl NCBI GeneCards UniProt Show fit	myomesin 1
chr5_+_167284799 Show fit	1.52	ENST00000518659.5	TENM2 Ensembl NCBI GeneCards UniProt Show fit	teneurin transmembrane protein 2
chr2_+_85429448 Show fit	1.50	ENST00000651736.1	SH2D6 Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 6
chrX_-_135764444 Show fit	1.50	ENST00000597510.6	CT45A3 Ensembl NCBI GeneCards UniProt Show fit	cancer/testis antigen family 45 member A3
chr11_-_7706394 Show fit	1.49	ENST00000612000.1	OVCH2 Ensembl NCBI GeneCards UniProt Show fit	ovochymase 2
chr2_+_172928165 Show fit	1.49	ENST00000535187.5	RAPGEF4 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 4
chrX_-_139205006 Show fit	1.49	ENST00000436198.5 ENST00000626909.2	FGF13 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 13
chrX_-_139204275 Show fit	1.48	ENST00000441825.8	FGF13 Ensembl NCBI GeneCards UniProt Show fit	fibroblast growth factor 13
chr10_-_69409275 Show fit	1.46	ENST00000373307.5	TACR2 Ensembl NCBI GeneCards UniProt Show fit	tachykinin receptor 2
chr16_-_30370396 Show fit	1.45	ENST00000409939.8	TBC1D10B Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 10B
chr1_+_244461386 Show fit	1.45	ENST00000366533.8 ENST00000428042.1	CATSPERE Ensembl NCBI GeneCards UniProt Show fit	catsper channel auxiliary subunit epsilon
chr7_-_22193824 Show fit	1.42	ENST00000401957.6	RAPGEF5 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 5
chr5_-_88824266 Show fit	1.41	ENST00000509373.1 ENST00000636541.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr17_-_42676980 Show fit	1.41	ENST00000587627.1 ENST00000591022.6 ENST00000293349.10	PLEKHH3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology, MyTH4 and FERM domain containing H3
chr19_-_48716827 Show fit	1.41	ENST00000595591.1 ENST00000356751.8 ENST00000594582.1	MAMSTR Ensembl NCBI GeneCards UniProt Show fit	MEF2 activating motif and SAP domain containing transcriptional regulator
chr8_+_78516329 Show fit	1.37	ENST00000396418.7 ENST00000352966.9	PKIA Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor alpha
chr2_-_55334529 Show fit	1.37	ENST00000645860.1 ENST00000642563.1 ENST00000647396.1	CCDC88A Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 88A
chr12_+_6913745 Show fit	1.36	ENST00000537688.5	ENO2 Ensembl NCBI GeneCards UniProt Show fit	enolase 2
chr14_+_63204436 Show fit	1.35	ENST00000316754.8	RHOJ Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member J
chr18_-_33136075 Show fit	1.32	ENST00000581852.5	CCDC178 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 178
chr2_-_174915283 Show fit	1.32	ENST00000490654.1 ENST00000652756.1	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr8_-_108787563 Show fit	1.31	ENST00000297459.4	TMEM74 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 74
chr1_-_48776811 Show fit	1.30	ENST00000371833.4	BEND5 Ensembl NCBI GeneCards UniProt Show fit	BEN domain containing 5
chr12_+_110846960 Show fit	1.30	ENST00000545036.5 ENST00000308208.10	CCDC63 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 63
chr12_-_109021015 Show fit	1.30	ENST00000546618.2 ENST00000610966.5	SVOP Ensembl NCBI GeneCards UniProt Show fit	SV2 related protein
chr5_+_161848112 Show fit	1.28	ENST00000393943.10	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr19_-_57457140 Show fit	1.27	ENST00000321039.5	VN1R1 Ensembl NCBI GeneCards UniProt Show fit	vomeronasal 1 receptor 1
chr2_-_65366650 Show fit	1.25	ENST00000443619.6	SPRED2 Ensembl NCBI GeneCards UniProt Show fit	sprouty related EVH1 domain containing 2
chrX_+_135252061 Show fit	1.25	ENST00000427686.3	ETDA Ensembl NCBI GeneCards UniProt Show fit	embryonic testis differentiation homolog A
chr1_-_21050952 Show fit	1.23	ENST00000264211.12	EIF4G3 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 4 gamma 3
chr6_+_158312459 Show fit	1.23	ENST00000367097.8	TULP4 Ensembl NCBI GeneCards UniProt Show fit	TUB like protein 4
chr10_+_49679637 Show fit	1.23	ENST00000374113.3 ENST00000374111.8 ENST00000374112.7 ENST00000535836.1	C10orf53 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 53
chr14_-_25010604 Show fit	1.19	ENST00000550887.5	STXBP6 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 6
chr21_-_26090035 Show fit	1.19	ENST00000448850.5	APP Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein
chr11_+_60327250 Show fit	1.18	ENST00000684409.1	MS4A6E Ensembl NCBI GeneCards UniProt Show fit	membrane spanning 4-domains A6E
chr16_-_46748337 Show fit	1.17	ENST00000394809.9	MYLK3 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain kinase 3
chr5_-_88824334 Show fit	1.14	ENST00000506716.5	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr15_-_66356672 Show fit	1.14	ENST00000261881.9	TIPIN Ensembl NCBI GeneCards UniProt Show fit	TIMELESS interacting protein
chr9_+_79572572 Show fit	1.13	ENST00000435650.5 ENST00000414465.5 ENST00000376537.8	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr4_-_99657820 Show fit	1.12	ENST00000511828.2	C4orf54 Ensembl NCBI GeneCards UniProt Show fit	chromosome 4 open reading frame 54
chr8_+_103819244 Show fit	1.08	ENST00000262231.14 ENST00000507740.5 ENST00000408894.6	RIMS2 Ensembl NCBI GeneCards UniProt Show fit	regulating synaptic membrane exocytosis 2
chr2_-_74343397 Show fit	1.08	ENST00000394019.6 ENST00000377634.8 ENST00000436454.1	SLC4A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 5
chr3_-_142028617 Show fit	1.08	ENST00000477292.5 ENST00000478006.5 ENST00000495310.5 ENST00000486111.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr13_-_33185994 Show fit	1.08	ENST00000255486.8	STARD13 Ensembl NCBI GeneCards UniProt Show fit	StAR related lipid transfer domain containing 13
chr10_+_122192442 Show fit	1.07	ENST00000514539.5	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr5_+_156326735 Show fit	1.06	ENST00000435422.7	SGCD Ensembl NCBI GeneCards UniProt Show fit	sarcoglycan delta
chr2_+_169584332 Show fit	1.06	ENST00000414307.6 ENST00000433207.6 ENST00000678088.1 ENST00000676508.1 ENST00000260970.8 ENST00000409714.7	PPIG Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase G
chr8_-_90082871 Show fit	1.05	ENST00000265431.7	CALB1 Ensembl NCBI GeneCards UniProt Show fit	calbindin 1
chr15_+_78873723 Show fit	1.05	ENST00000559690.5 ENST00000559158.5	MORF4L1 Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr1_+_160400543 Show fit	1.05	ENST00000368061.3	VANGL2 Ensembl NCBI GeneCards UniProt Show fit	VANGL planar cell polarity protein 2
chr8_+_91102645 Show fit	1.04	ENST00000343709.7 ENST00000448384.2	LRRC69 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 69
chr1_+_156126160 Show fit	1.03	ENST00000448611.6 ENST00000368297.5	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr6_+_41053194 Show fit	1.02	ENST00000244669.3	APOBEC2 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr16_-_67483541 Show fit	1.00	ENST00000290953.3	AGRP Ensembl NCBI GeneCards UniProt Show fit	agouti related neuropeptide
chrX_-_135781729 Show fit	0.98	ENST00000617203.1	CT45A5 Ensembl NCBI GeneCards UniProt Show fit	cancer/testis antigen family 45 member A5
chr8_+_96584920 Show fit	0.97	ENST00000521590.5	SDC2 Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chr14_-_59630582 Show fit	0.97	ENST00000395090.5	RTN1 Ensembl NCBI GeneCards UniProt Show fit	reticulon 1
chr14_+_88385714 Show fit	0.96	ENST00000045347.11	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr1_+_244461270 Show fit	0.96	ENST00000366534.9	CATSPERE Ensembl NCBI GeneCards UniProt Show fit	catsper channel auxiliary subunit epsilon
chr6_-_26043704 Show fit	0.95	ENST00000615966.2	H2BC3 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 3
chr16_+_14748066 Show fit	0.94	ENST00000530328.5 ENST00000529166.5	NPIPA2 Ensembl NCBI GeneCards UniProt Show fit	nuclear pore complex interacting protein family member A2
chr1_-_114153863 Show fit	0.93	ENST00000610222.3 ENST00000369547.6 ENST00000641643.2	SYT6 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 6
chr10_-_99235846 Show fit	0.92	ENST00000370552.8 ENST00000370549.5 ENST00000628193.2	HPSE2 Ensembl NCBI GeneCards UniProt Show fit	heparanase 2 (inactive)
chr1_+_244461370 Show fit	0.90	ENST00000366531.7	CATSPERE Ensembl NCBI GeneCards UniProt Show fit	catsper channel auxiliary subunit epsilon
chr3_+_68004231 Show fit	0.88	ENST00000478136.6	TAFA1 Ensembl NCBI GeneCards UniProt Show fit	TAFA chemokine like family member 1
chr12_+_25052663 Show fit	0.87	ENST00000556887.5	IRAG2 Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-triphosphate receptor associated 2
chr19_+_12064720 Show fit	0.85	ENST00000550826.1 ENST00000439326.8	ZNF844 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 844
chr6_-_87095059 Show fit	0.84	ENST00000369582.6 ENST00000610310.3 ENST00000630630.2 ENST00000627148.3 ENST00000625577.1	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chrX_-_135799001 Show fit	0.82	ENST00000612878.4	CT45A6 Ensembl NCBI GeneCards UniProt Show fit	cancer/testis antigen family 45 member A6
chr3_-_74521140 Show fit	0.82	ENST00000263665.6	CNTN3 Ensembl NCBI GeneCards UniProt Show fit	contactin 3
chr3_-_142028597 Show fit	0.80	ENST00000467667.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr9_+_79572715 Show fit	0.79	ENST00000265284.10	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr1_-_175023408 Show fit	0.79	ENST00000476371.1	MRPS14 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S14
chrX_-_135833541 Show fit	0.78	ENST00000620885.1	CT45A7 Ensembl NCBI GeneCards UniProt Show fit	cancer/testis antigen family 45 member A7
chr16_+_19410723 Show fit	0.78	ENST00000381414.8 ENST00000396229.6	TMC5 Ensembl NCBI GeneCards UniProt Show fit	transmembrane channel like 5
chr12_-_27971970 Show fit	0.77	ENST00000395872.5 ENST00000201015.8	PTHLH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone like hormone
chr20_-_25390776 Show fit	0.76	ENST00000376542.8 ENST00000339157.10	ABHD12 Ensembl NCBI GeneCards UniProt Show fit	abhydrolase domain containing 12, lysophospholipase
chr18_+_34710307 Show fit	0.74	ENST00000679796.1	DTNA Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr9_+_85941121 Show fit	0.73	ENST00000361671.10	NAA35 Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr2_-_206159410 Show fit	0.72	ENST00000457011.5 ENST00000440274.5 ENST00000432169.5 ENST00000233190.11	NDUFS1 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase core subunit S1
chrX_-_31178220 Show fit	0.72	ENST00000681026.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr6_-_159788439 Show fit	0.71	ENST00000539948.5	TCP1 Ensembl NCBI GeneCards UniProt Show fit	t-complex 1
chr5_-_56116946 Show fit	0.71	ENST00000434982.2	ANKRD55 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 55
chr2_+_209579315 Show fit	0.70	ENST00000392193.5	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr7_-_113087720 Show fit	0.70	ENST00000297146.7	GPR85 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 85
chr17_+_75667390 Show fit	0.69	ENST00000583536.5	SAP30BP Ensembl NCBI GeneCards UniProt Show fit	SAP30 binding protein
chr19_+_4402615 Show fit	0.68	ENST00000301280.10	CHAF1A Ensembl NCBI GeneCards UniProt Show fit	chromatin assembly factor 1 subunit A
chr5_-_146878595 Show fit	0.66	ENST00000394409.7	PPP2R2B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Bbeta
chrX_-_31178149 Show fit	0.66	ENST00000679437.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr12_+_110847000 Show fit	0.66	ENST00000552694.1	CCDC63 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 63
chr3_+_141262614 Show fit	0.65	ENST00000504264.5	PXYLP1 Ensembl NCBI GeneCards UniProt Show fit	2-phosphoxylose phosphatase 1
chr18_+_79069385 Show fit	0.65	ENST00000426216.6 ENST00000307671.12 ENST00000586672.5 ENST00000586722.5	ATP9B Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 9B (putative)
chr3_+_178558700 Show fit	0.64	ENST00000432997.5 ENST00000455865.5	KCNMB2 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 2
chrX_-_135868069 Show fit	0.60	ENST00000604569.1	CT45A9 Ensembl NCBI GeneCards UniProt Show fit	cancer/testis antigen family 45 member A9
chr5_+_162068031 Show fit	0.60	ENST00000356592.8	GABRG2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.5	10.5	GO:1904204	regulation of skeletal muscle hypertrophy(GO:1904204)
2.3	9.0	GO:0030185	nitric oxide transport(GO:0030185)
1.5	4.4	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.9	6.9	GO:0007412	axon target recognition(GO:0007412)
0.8	2.5	GO:0061033	secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7	11.1	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.6	1.2	GO:0048769	sarcomerogenesis(GO:0048769)
0.6	3.5	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.6	2.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.5	2.7	GO:2000866	positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5	11.9	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.5	2.4	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5	4.1	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.4	3.0	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4	2.4	GO:0051585	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4	1.8	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.3	4.4	GO:0019695	choline metabolic process(GO:0019695)
0.3	1.9	GO:0006772	thiamine metabolic process(GO:0006772)
0.3	1.5	GO:0035106	operant conditioning(GO:0035106)
0.3	3.3	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.3	1.1	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.3	2.7	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.3	1.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3	2.8	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2	0.7	GO:0044417	translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.2	1.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.2	1.6	GO:0018032	protein amidation(GO:0018032)
0.2	4.9	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.2	1.4	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.2	2.7	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.2	6.0	GO:0003334	keratinocyte development(GO:0003334)
0.2	2.0	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.2	0.7	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2	5.6	GO:0006068	ethanol catabolic process(GO:0006068)
0.2	12.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.2	3.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	3.8	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	3.2	GO:0048664	neuron fate determination(GO:0048664)
0.2	0.8	GO:0052651	monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2	0.6	GO:0061300	cerebellum vasculature development(GO:0061300)
0.2	1.1	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.2	1.0	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2	4.9	GO:0071420	cellular response to histamine(GO:0071420)
0.2	1.0	GO:0008218	bioluminescence(GO:0008218)
0.2	1.3	GO:0019236	response to pheromone(GO:0019236)
0.2	2.5	GO:2000389	regulation of neutrophil extravasation(GO:2000389)
0.2	0.9	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.2	3.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.1	1.3	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	1.1	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.1	1.1	GO:0048478	replication fork protection(GO:0048478)
0.1	0.4	GO:0031247	actin rod assembly(GO:0031247)
0.1	4.3	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.1	1.7	GO:0008090	retrograde axonal transport(GO:0008090)
0.1	2.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	1.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1	1.6	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	1.2	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.1	1.0	GO:0008343	adult feeding behavior(GO:0008343)
0.1	1.8	GO:0045475	locomotor rhythm(GO:0045475)
0.1	2.0	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	0.5	GO:0061760	antifungal innate immune response(GO:0061760)
0.1	1.6	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.6	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.1	1.4	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	12.8	GO:0021954	central nervous system neuron development(GO:0021954)
0.1	2.3	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	0.5	GO:0033029	regulation of neutrophil apoptotic process(GO:0033029)
0.1	0.9	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	4.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.5	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.1	4.4	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1	1.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	8.1	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.1	1.2	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1	2.6	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1	4.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	1.2	GO:0097264	self proteolysis(GO:0097264)
0.0	2.4	GO:0035640	exploration behavior(GO:0035640)
0.0	2.6	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	1.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	4.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.7	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.4	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	2.4	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.7	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.0	2.7	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	1.4	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	1.2	GO:0061512	protein localization to cilium(GO:0061512)
0.0	0.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	3.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.3	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.6	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.7	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	1.3	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	5.7	GO:0007626	locomotory behavior(GO:0007626)
0.0	0.5	GO:1900115	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.6	GO:0045332	phospholipid translocation(GO:0045332)
0.0	3.8	GO:0051781	positive regulation of cell division(GO:0051781)
0.0	1.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	2.5	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	2.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	1.7	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.5	GO:0006833	water transport(GO:0006833)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	1.8	GO:1902476	chloride transmembrane transport(GO:1902476)
0.0	0.8	GO:0016486	peptide hormone processing(GO:0016486)
0.0	0.1	GO:1901377	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0	0.5	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	0.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.3	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.9	3.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.9	10.5	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.8	9.1	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.8	3.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.7	4.1	GO:1990131	Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4	4.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.3	1.0	GO:0060187	cell pole(GO:0060187)
0.3	2.2	GO:0000801	central element(GO:0000801)
0.3	8.4	GO:0032982	myosin filament(GO:0032982)
0.3	3.3	GO:0036128	CatSper complex(GO:0036128)
0.2	1.7	GO:0031673	H zone(GO:0031673)
0.2	0.6	GO:0042720	mitochondrial inner membrane peptidase complex(GO:0042720)
0.1	0.7	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
0.1	9.2	GO:1904115	axon cytoplasm(GO:1904115)
0.1	4.9	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	1.2	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	2.3	GO:0008091	spectrin(GO:0008091)
0.1	0.7	GO:0031417	NatC complex(GO:0031417)
0.1	1.0	GO:0005638	lamin filament(GO:0005638)
0.1	1.1	GO:0031298	replication fork protection complex(GO:0031298)
0.1	6.8	GO:0002102	podosome(GO:0002102)
0.1	11.1	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	1.4	GO:0016013	syntrophin complex(GO:0016013)
0.1	3.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.1	0.5	GO:0071942	XPC complex(GO:0071942)
0.1	2.7	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	2.2	GO:0043194	axon initial segment(GO:0043194)
0.1	1.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.1	1.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.7	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.0	1.1	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.4	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	2.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	2.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.2	GO:0000145	exocyst(GO:0000145)
0.0	10.1	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.8	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.4	GO:0070938	contractile ring(GO:0070938)
0.0	4.1	GO:0005811	lipid particle(GO:0005811)
0.0	3.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	2.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	1.3	GO:0000421	autophagosome membrane(GO:0000421)
0.0	3.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	2.5	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	0.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	3.0	GO:0014704	intercalated disc(GO:0014704)
0.0	2.9	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	2.8	GO:0005796	Golgi lumen(GO:0005796)
0.0	4.1	GO:0042383	sarcolemma(GO:0042383)
0.0	3.5	GO:0005882	intermediate filament(GO:0005882)
0.0	2.0	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	1.1	GO:0043195	terminal bouton(GO:0043195)
0.0	3.0	GO:0005814	centriole(GO:0005814)
0.0	3.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.9	GO:0048786	presynaptic active zone(GO:0048786)
0.0	1.8	GO:0005902	microvillus(GO:0005902)
0.0	8.9	GO:0098794	postsynapse(GO:0098794)
0.0	2.4	GO:0031902	late endosome membrane(GO:0031902)
0.0	1.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	5.9	GO:0030133	transport vesicle(GO:0030133)
0.0	1.6	GO:0030018	Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	6.9	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
1.1	4.4	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.9	5.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.8	3.3	GO:0030379	neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.8	10.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.6	11.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.5	3.7	GO:0030492	hemoglobin binding(GO:0030492)
0.5	4.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5	1.5	GO:0016497	substance K receptor activity(GO:0016497)
0.5	18.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	3.9	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4	1.3	GO:0016503	pheromone receptor activity(GO:0016503)
0.4	2.4	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.4	1.9	GO:0004802	transketolase activity(GO:0004802)
0.4	2.2	GO:0003998	acylphosphatase activity(GO:0003998)
0.4	4.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.3	10.5	GO:0002162	dystroglycan binding(GO:0002162)
0.3	1.8	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3	3.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.3	2.0	GO:0005534	galactose binding(GO:0005534)
0.3	1.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	3.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	5.6	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.2	1.6	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2	1.8	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	2.3	GO:0042731	PH domain binding(GO:0042731)
0.2	12.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.2	1.6	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	3.0	GO:0043295	glutathione binding(GO:0043295)
0.1	2.6	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	1.1	GO:0005499	vitamin D binding(GO:0005499)
0.1	4.0	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	6.0	GO:0071837	HMG box domain binding(GO:0071837)
0.1	1.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0030305	heparanase activity(GO:0030305)
0.1	1.2	GO:0051425	PTB domain binding(GO:0051425)
0.1	1.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	1.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	6.5	GO:0050699	WW domain binding(GO:0050699)
0.1	5.5	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	2.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.4	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1	2.0	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.5	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1	1.2	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	2.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	1.6	GO:0048156	tau protein binding(GO:0048156)
0.1	1.8	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	1.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.5	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	1.4	GO:0043422	protein kinase B binding(GO:0043422)
0.0	2.5	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0032093	SAM domain binding(GO:0032093)
0.0	1.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	3.0	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	1.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein kinase A catalytic subunit binding(GO:0034236)
0.0	1.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	3.5	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.0	6.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	1.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	5.0	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	2.9	GO:0019003	GDP binding(GO:0019003)
0.0	5.0	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.5	GO:0015250	water channel activity(GO:0015250)
0.0	2.5	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	1.0	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	5.5	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.7	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.7	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.7	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.3	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	4.1	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	6.9	GO:0003924	GTPase activity(GO:0003924)
0.0	4.2	GO:0008083	growth factor activity(GO:0008083)
0.0	0.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.7	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	1.9	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.5	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.5	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.9	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	2.4	GO:0005125	cytokine activity(GO:0005125)
0.0	1.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.8	GO:0005179	hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	5.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	9.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	2.6	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	12.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	9.1	PID LKB1 PATHWAY	LKB1 signaling events
0.1	1.8	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	2.7	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	5.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	8.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	3.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	4.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	3.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	2.8	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	3.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	12.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.3	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.8	PID ATR PATHWAY	ATR signaling pathway
0.0	1.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	2.1	PID NOTCH PATHWAY	Notch signaling pathway
0.0	7.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.6	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.8	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	5.6	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	10.5	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	5.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	10.1	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	4.9	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	3.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	2.5	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	3.6	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	3.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	4.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.1	0.8	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.1	2.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	2.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1	4.9	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	1.3	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	2.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	3.3	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	3.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	9.4	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	1.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	2.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	2.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	1.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	4.9	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	6.5	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.7	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	2.1	REACTOME SIGNALING BY NOTCH1	Genes involved in Signaling by NOTCH1
0.0	3.4	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	2.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes

Results for NKX6-2

Z-value: 1.58

Motif logo

Transcription factors associated with NKX6-2

Activity-expression correlation:

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: