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Illumina Body Map 2 (GSE30611)

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Results for NKX6-2

Z-value: 1.58

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Transcription factors associated with NKX6-2

Gene Symbol Gene ID Gene Info
ENSG00000148826.9 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-2hg38_v1_chr10_-_132786146_1327861490.862.2e-10Click!

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_101594849 8.76 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr8_+_24440930 7.46 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr4_+_41256921 6.88 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr3_+_39467598 6.11 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
myelin associated oligodendrocyte basic protein
chr2_-_216695540 5.99 ENST00000233813.5
insulin like growth factor binding protein 5
chrX_-_81201886 5.48 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr6_+_12290353 5.33 ENST00000379375.6
endothelin 1
chr1_+_110451132 5.22 ENST00000271331.4
prokineticin 1
chr3_+_39467672 4.96 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
myelin associated oligodendrocyte basic protein
chr17_-_44915486 4.85 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chrX_+_103585478 4.60 ENST00000468024.5
ENST00000415568.2
ENST00000472484.6
ENST00000613326.4
ENST00000490644.5
ENST00000459722.1
ENST00000472745.1
ENST00000494801.5
ENST00000434216.2
transcription elongation factor A like 4
chr2_-_216694794 4.54 ENST00000449583.1
insulin like growth factor binding protein 5
chr4_-_184217854 4.40 ENST00000296741.7
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr7_-_137343752 4.39 ENST00000393083.2
pleiotrophin
chr13_-_35855758 4.30 ENST00000615680.4
doublecortin like kinase 1
chr3_-_98522514 4.23 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr4_+_168497066 4.18 ENST00000261509.10
palladin, cytoskeletal associated protein
chr14_-_26597430 3.74 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA alternative splicing regulator 1
chr11_-_5227063 3.68 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr2_-_174847250 3.65 ENST00000409089.7
chimerin 1
chr2_-_174847765 3.61 ENST00000443238.6
chimerin 1
chr5_+_95731300 3.58 ENST00000379982.8
Rho related BTB domain containing 3
chr2_+_209579598 3.57 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr2_-_174847525 3.57 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr3_-_79767987 3.49 ENST00000464233.6
roundabout guidance receptor 1
chr2_+_232662733 3.35 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr18_+_34710249 3.32 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr4_+_168497044 3.31 ENST00000505667.6
palladin, cytoskeletal associated protein
chr1_-_109393197 3.31 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr4_-_86453075 3.19 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10
chr1_+_170663134 3.16 ENST00000367760.7
paired related homeobox 1
chr2_+_108378176 3.15 ENST00000409309.3
sulfotransferase family 1C member 4
chr2_+_209579399 3.13 ENST00000360351.8
microtubule associated protein 2
chr9_-_23826231 3.05 ENST00000397312.7
ELAV like RNA binding protein 2
chr8_-_81483226 3.04 ENST00000256104.5
fatty acid binding protein 4
chr12_+_6914571 3.03 ENST00000229277.6
ENST00000538763.5
ENST00000545045.6
enolase 2
chrX_-_103832204 3.00 ENST00000674363.1
ENST00000674162.1
ENST00000674338.1
ENST00000674274.1
ENST00000674271.1
ENST00000674265.1
ENST00000674212.1
ENST00000674255.1
ENST00000674342.1
ENST00000674430.1
ENST00000243298.3
novel transcript
RAB9B, member RAS oncogene family
chr2_-_210477562 2.99 ENST00000448951.5
LanC like 1
chr1_-_243163310 2.87 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr4_+_87975667 2.73 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chrX_+_136148440 2.71 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr9_+_127264740 2.70 ENST00000373387.9
GTPase activating Rap/RanGAP domain like 3
chr18_-_12656716 2.68 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr3_+_319683 2.67 ENST00000620033.4
cell adhesion molecule L1 like
chr12_+_40742342 2.62 ENST00000548005.5
ENST00000552248.5
contactin 1
chr2_-_73293538 2.61 ENST00000436467.4
ENST00000545030.1
early growth response 4
chr5_+_161848314 2.59 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr11_+_122882683 2.52 ENST00000307257.10
ENST00000227349.7
junctional cadherin complex regulator
chr13_+_53028806 2.51 ENST00000219022.3
olfactomedin 4
chr2_+_108377947 2.48 ENST00000272452.7
sulfotransferase family 1C member 4
chr15_-_48963912 2.48 ENST00000332408.9
SHC adaptor protein 4
chr5_+_145936554 2.48 ENST00000359120.9
SH3 domain containing ring finger 2
chr15_+_49423233 2.47 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chrX_+_10156960 2.40 ENST00000380833.9
chloride voltage-gated channel 4
chr4_-_89838289 2.38 ENST00000336904.7
synuclein alpha
chr3_+_159839847 2.37 ENST00000445224.6
schwannomin interacting protein 1
chr4_-_139280179 2.36 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr16_+_56191476 2.33 ENST00000262493.12
G protein subunit alpha o1
chr6_-_130956371 2.33 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr1_+_85062304 2.28 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr13_-_44474296 2.26 ENST00000611198.4
TSC22 domain family member 1
chr1_+_114854858 2.24 ENST00000369522.8
ENST00000455987.5
ENST00000618516.4
ENST00000613524.4
synaptonemal complex protein 1
chr14_-_75063990 2.22 ENST00000555135.1
ENST00000357971.7
ENST00000553302.1
ENST00000238618.8
ENST00000555694.5
acylphosphatase 1
chr9_+_79571956 2.19 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr3_+_16174628 2.19 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr1_+_107139996 2.19 ENST00000370073.6
ENST00000370074.8
netrin G1
chrX_+_55717733 2.15 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr1_-_110391041 2.14 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr1_-_247723764 2.13 ENST00000419891.1
novel protein
chr21_-_35049327 2.11 ENST00000300305.7
RUNX family transcription factor 1
chr9_-_28670285 2.09 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr1_+_244352627 2.08 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr14_-_59630806 2.04 ENST00000342503.8
reticulon 1
chr11_-_7706469 2.01 ENST00000533663.6
ovochymase 2
chr18_-_500692 2.01 ENST00000400256.5
collectin subfamily member 12
chr14_-_26598025 1.99 ENST00000539517.7
NOVA alternative splicing regulator 1
chrX_+_55717796 1.97 ENST00000262850.7
Ras related GTP binding B
chr7_-_108240049 1.97 ENST00000379022.8
neuronal cell adhesion molecule
chrX_+_103585615 1.94 ENST00000425011.1
transcription elongation factor A like 4
chr9_-_23826299 1.94 ENST00000380117.5
ELAV like RNA binding protein 2
chrX_+_154304923 1.93 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
transketolase like 1
chr6_-_79537423 1.93 ENST00000369846.9
ENST00000392959.5
ENST00000467898.3
lebercilin LCA5
chr1_-_110390989 1.91 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr17_-_69060906 1.87 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr17_+_29941605 1.86 ENST00000394835.7
EF-hand calcium binding domain 5
chr7_+_120273129 1.81 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr3_+_16174703 1.80 ENST00000437509.3
polypeptide N-acetylgalactosaminyltransferase 15
chr1_+_86547070 1.77 ENST00000370563.3
chloride channel accessory 4
chr4_+_54229261 1.77 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr14_+_88385643 1.75 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr6_-_56851888 1.73 ENST00000312431.10
ENST00000520645.5
dystonin
chr1_-_190477854 1.73 ENST00000367462.5
BMP/retinoic acid inducible neural specific 3
chr2_+_209579429 1.72 ENST00000361559.8
microtubule associated protein 2
chrX_-_135120526 1.69 ENST00000423661.1
embryonic testis differentiation homolog B
chr21_-_35049238 1.69 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chrX_+_34942790 1.68 ENST00000329357.6
family with sequence similarity 47 member B
chr18_-_36798482 1.64 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr1_-_247724043 1.64 ENST00000366485.1
olfactory receptor family 14 subfamily A member 2
chr5_+_102808057 1.63 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr18_-_3219849 1.61 ENST00000261606.11
myomesin 1
chr5_-_20575850 1.58 ENST00000507958.5
cadherin 18
chr8_-_42501224 1.57 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr8_+_26293112 1.57 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr16_+_14708944 1.56 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chr1_+_77918128 1.56 ENST00000342754.5
nexilin F-actin binding protein
chr18_-_3219961 1.53 ENST00000356443.9
myomesin 1
chr5_+_167284799 1.52 ENST00000518659.5
teneurin transmembrane protein 2
chr2_+_85429448 1.50 ENST00000651736.1
SH2 domain containing 6
chrX_-_135764444 1.50 ENST00000597510.6
cancer/testis antigen family 45 member A3
chr11_-_7706394 1.49 ENST00000612000.1
ovochymase 2
chr2_+_172928165 1.49 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chrX_-_139205006 1.49 ENST00000436198.5
ENST00000626909.2
fibroblast growth factor 13
chrX_-_139204275 1.48 ENST00000441825.8
fibroblast growth factor 13
chr10_-_69409275 1.46 ENST00000373307.5
tachykinin receptor 2
chr16_-_30370396 1.45 ENST00000409939.8
TBC1 domain family member 10B
chr1_+_244461386 1.45 ENST00000366533.8
ENST00000428042.1
catsper channel auxiliary subunit epsilon
chr7_-_22193824 1.42 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr5_-_88824266 1.41 ENST00000509373.1
ENST00000636541.1
myocyte enhancer factor 2C
chr17_-_42676980 1.41 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr19_-_48716827 1.41 ENST00000595591.1
ENST00000356751.8
ENST00000594582.1
MEF2 activating motif and SAP domain containing transcriptional regulator
chr8_+_78516329 1.37 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr2_-_55334529 1.37 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr12_+_6913745 1.36 ENST00000537688.5
enolase 2
chr14_+_63204436 1.35 ENST00000316754.8
ras homolog family member J
chr18_-_33136075 1.32 ENST00000581852.5
coiled-coil domain containing 178
chr2_-_174915283 1.32 ENST00000490654.1
ENST00000652756.1
chimerin 1
chr8_-_108787563 1.31 ENST00000297459.4
transmembrane protein 74
chr1_-_48776811 1.30 ENST00000371833.4
BEN domain containing 5
chr12_+_110846960 1.30 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr12_-_109021015 1.30 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr5_+_161848112 1.28 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr19_-_57457140 1.27 ENST00000321039.5
vomeronasal 1 receptor 1
chr2_-_65366650 1.25 ENST00000443619.6
sprouty related EVH1 domain containing 2
chrX_+_135252061 1.25 ENST00000427686.3
embryonic testis differentiation homolog A
chr1_-_21050952 1.23 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr6_+_158312459 1.23 ENST00000367097.8
TUB like protein 4
chr10_+_49679637 1.23 ENST00000374113.3
ENST00000374111.8
ENST00000374112.7
ENST00000535836.1
chromosome 10 open reading frame 53
chr14_-_25010604 1.19 ENST00000550887.5
syntaxin binding protein 6
chr21_-_26090035 1.19 ENST00000448850.5
amyloid beta precursor protein
chr11_+_60327250 1.18 ENST00000684409.1
membrane spanning 4-domains A6E
chr16_-_46748337 1.17 ENST00000394809.9
myosin light chain kinase 3
chr5_-_88824334 1.14 ENST00000506716.5
myocyte enhancer factor 2C
chr15_-_66356672 1.14 ENST00000261881.9
TIMELESS interacting protein
chr9_+_79572572 1.13 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr4_-_99657820 1.12 ENST00000511828.2
chromosome 4 open reading frame 54
chr8_+_103819244 1.08 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr2_-_74343397 1.08 ENST00000394019.6
ENST00000377634.8
ENST00000436454.1
solute carrier family 4 member 5
chr3_-_142028617 1.08 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
transcription factor Dp-2
chr13_-_33185994 1.08 ENST00000255486.8
StAR related lipid transfer domain containing 13
chr10_+_122192442 1.07 ENST00000514539.5
transforming acidic coiled-coil containing protein 2
chr5_+_156326735 1.06 ENST00000435422.7
sarcoglycan delta
chr2_+_169584332 1.06 ENST00000414307.6
ENST00000433207.6
ENST00000678088.1
ENST00000676508.1
ENST00000260970.8
ENST00000409714.7
peptidylprolyl isomerase G
chr8_-_90082871 1.05 ENST00000265431.7
calbindin 1
chr15_+_78873723 1.05 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr1_+_160400543 1.05 ENST00000368061.3
VANGL planar cell polarity protein 2
chr8_+_91102645 1.04 ENST00000343709.7
ENST00000448384.2
leucine rich repeat containing 69
chr1_+_156126160 1.03 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr6_+_41053194 1.02 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr16_-_67483541 1.00 ENST00000290953.3
agouti related neuropeptide
chrX_-_135781729 0.98 ENST00000617203.1
cancer/testis antigen family 45 member A5
chr8_+_96584920 0.97 ENST00000521590.5
syndecan 2
chr14_-_59630582 0.97 ENST00000395090.5
reticulon 1
chr14_+_88385714 0.96 ENST00000045347.11
spermatogenesis associated 7
chr1_+_244461270 0.96 ENST00000366534.9
catsper channel auxiliary subunit epsilon
chr6_-_26043704 0.95 ENST00000615966.2
H2B clustered histone 3
chr16_+_14748066 0.94 ENST00000530328.5
ENST00000529166.5
nuclear pore complex interacting protein family member A2
chr1_-_114153863 0.93 ENST00000610222.3
ENST00000369547.6
ENST00000641643.2
synaptotagmin 6
chr10_-_99235846 0.92 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr1_+_244461370 0.90 ENST00000366531.7
catsper channel auxiliary subunit epsilon
chr3_+_68004231 0.88 ENST00000478136.6
TAFA chemokine like family member 1
chr12_+_25052663 0.87 ENST00000556887.5
inositol 1,4,5-triphosphate receptor associated 2
chr19_+_12064720 0.85 ENST00000550826.1
ENST00000439326.8
zinc finger protein 844
chr6_-_87095059 0.84 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chrX_-_135799001 0.82 ENST00000612878.4
cancer/testis antigen family 45 member A6
chr3_-_74521140 0.82 ENST00000263665.6
contactin 3
chr3_-_142028597 0.80 ENST00000467667.5
transcription factor Dp-2
chr9_+_79572715 0.79 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chr1_-_175023408 0.79 ENST00000476371.1
mitochondrial ribosomal protein S14
chrX_-_135833541 0.78 ENST00000620885.1
cancer/testis antigen family 45 member A7
chr16_+_19410723 0.78 ENST00000381414.8
ENST00000396229.6
transmembrane channel like 5
chr12_-_27971970 0.77 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr20_-_25390776 0.76 ENST00000376542.8
ENST00000339157.10
abhydrolase domain containing 12, lysophospholipase
chr18_+_34710307 0.74 ENST00000679796.1
dystrobrevin alpha
chr9_+_85941121 0.73 ENST00000361671.10
N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr2_-_206159410 0.72 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chrX_-_31178220 0.72 ENST00000681026.1
dystrophin
chr6_-_159788439 0.71 ENST00000539948.5
t-complex 1
chr5_-_56116946 0.71 ENST00000434982.2
ankyrin repeat domain 55
chr2_+_209579315 0.70 ENST00000392193.5
microtubule associated protein 2
chr7_-_113087720 0.70 ENST00000297146.7
G protein-coupled receptor 85
chr17_+_75667390 0.69 ENST00000583536.5
SAP30 binding protein
chr19_+_4402615 0.68 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr5_-_146878595 0.66 ENST00000394409.7
protein phosphatase 2 regulatory subunit Bbeta
chrX_-_31178149 0.66 ENST00000679437.1
dystrophin
chr12_+_110847000 0.66 ENST00000552694.1
coiled-coil domain containing 63
chr3_+_141262614 0.65 ENST00000504264.5
2-phosphoxylose phosphatase 1
chr18_+_79069385 0.65 ENST00000426216.6
ENST00000307671.12
ENST00000586672.5
ENST00000586722.5
ATPase phospholipid transporting 9B (putative)
chr3_+_178558700 0.64 ENST00000432997.5
ENST00000455865.5
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chrX_-_135868069 0.60 ENST00000604569.1
cancer/testis antigen family 45 member A9
chr5_+_162068031 0.60 ENST00000356592.8
gamma-aminobutyric acid type A receptor subunit gamma2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
2.3 9.0 GO:0030185 nitric oxide transport(GO:0030185)
1.5 4.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.9 6.9 GO:0007412 axon target recognition(GO:0007412)
0.8 2.5 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.7 11.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.6 1.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.6 3.5 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.6 2.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.5 2.7 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5 11.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 2.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5 4.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.4 3.0 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4 2.4 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 1.8 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.3 4.4 GO:0019695 choline metabolic process(GO:0019695)
0.3 1.9 GO:0006772 thiamine metabolic process(GO:0006772)
0.3 1.5 GO:0035106 operant conditioning(GO:0035106)
0.3 3.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 1.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 2.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.3 1.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.3 2.8 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.7 GO:0044417 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.2 1.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 1.6 GO:0018032 protein amidation(GO:0018032)
0.2 4.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 1.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 2.7 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.2 6.0 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.7 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 5.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 12.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 3.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 3.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 3.2 GO:0048664 neuron fate determination(GO:0048664)
0.2 0.8 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.0 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 4.9 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.0 GO:0008218 bioluminescence(GO:0008218)
0.2 1.3 GO:0019236 response to pheromone(GO:0019236)
0.2 2.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.2 0.9 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 3.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.1 GO:0048478 replication fork protection(GO:0048478)
0.1 0.4 GO:0031247 actin rod assembly(GO:0031247)
0.1 4.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 1.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.0 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.8 GO:0045475 locomotor rhythm(GO:0045475)
0.1 2.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 1.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 12.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 2.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.9 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 4.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 4.4 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 8.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.6 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 4.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.2 GO:0097264 self proteolysis(GO:0097264)
0.0 2.4 GO:0035640 exploration behavior(GO:0035640)
0.0 2.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 4.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 2.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 2.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 1.4 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 1.2 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 3.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.3 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 5.7 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.5 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 3.8 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.5 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 1.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.5 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.9 3.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.9 10.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.8 9.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.8 3.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.7 4.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 4.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.3 2.2 GO:0000801 central element(GO:0000801)
0.3 8.4 GO:0032982 myosin filament(GO:0032982)
0.3 3.3 GO:0036128 CatSper complex(GO:0036128)
0.2 1.7 GO:0031673 H zone(GO:0031673)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 9.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 4.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 2.3 GO:0008091 spectrin(GO:0008091)
0.1 0.7 GO:0031417 NatC complex(GO:0031417)
0.1 1.0 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0031298 replication fork protection complex(GO:0031298)
0.1 6.8 GO:0002102 podosome(GO:0002102)
0.1 11.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.4 GO:0016013 syntrophin complex(GO:0016013)
0.1 3.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0071942 XPC complex(GO:0071942)
0.1 2.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.2 GO:0043194 axon initial segment(GO:0043194)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.0 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 10.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 4.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 2.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 3.0 GO:0014704 intercalated disc(GO:0014704)
0.0 2.9 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 4.1 GO:0042383 sarcolemma(GO:0042383)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)
0.0 2.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 3.0 GO:0005814 centriole(GO:0005814)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 8.9 GO:0098794 postsynapse(GO:0098794)
0.0 2.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 5.9 GO:0030133 transport vesicle(GO:0030133)
0.0 1.6 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.1 4.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.9 5.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.8 3.3 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.8 10.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.6 11.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 3.7 GO:0030492 hemoglobin binding(GO:0030492)
0.5 4.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.5 1.5 GO:0016497 substance K receptor activity(GO:0016497)
0.5 18.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 3.9 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.4 1.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.4 2.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 1.9 GO:0004802 transketolase activity(GO:0004802)
0.4 2.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.4 4.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 10.5 GO:0002162 dystroglycan binding(GO:0002162)
0.3 1.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 3.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.0 GO:0005534 galactose binding(GO:0005534)
0.3 1.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 3.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 5.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.6 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 2.3 GO:0042731 PH domain binding(GO:0042731)
0.2 12.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 3.0 GO:0043295 glutathione binding(GO:0043295)
0.1 2.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.1 4.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 6.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0030305 heparanase activity(GO:0030305)
0.1 1.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 6.5 GO:0050699 WW domain binding(GO:0050699)
0.1 5.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 2.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.5 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.6 GO:0048156 tau protein binding(GO:0048156)
0.1 1.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 6.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 5.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.9 GO:0019003 GDP binding(GO:0019003)
0.0 5.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 2.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 5.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 6.9 GO:0003924 GTPase activity(GO:0003924)
0.0 4.2 GO:0008083 growth factor activity(GO:0008083)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.4 GO:0005125 cytokine activity(GO:0005125)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 5.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 9.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 12.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 9.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 5.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 8.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 3.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 4.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 3.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 12.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 5.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 5.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 10.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 4.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 3.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 4.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 2.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 3.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 9.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 1.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 4.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 6.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.1 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 3.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes