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Illumina Body Map 2 (GSE30611)

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.74

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
ENSG00000214513.4 notochord homeobox
ENSG00000119614.3 visual system homeobox 2
ENSG00000115844.11 distal-less homeobox 2
ENSG00000006377.11 distal-less homeobox 6
ENSG00000163623.10 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX6hg38_v1_chr7_+_97005538_97005562-0.251.6e-01Click!
DLX2hg38_v1_chr2_-_172102893_172102909-0.232.0e-01Click!
NOTOhg38_v1_chr2_+_73202570_73202577-0.183.1e-01Click!
VSX2hg38_v1_chr14_+_74239447_74239452-0.134.9e-01Click!
NKX6-1hg38_v1_chr4_-_84499281_844992980.029.4e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_91249307 4.13 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr17_-_10518536 4.00 ENST00000226207.6
myosin heavy chain 1
chr17_-_66229380 3.48 ENST00000205948.11
apolipoprotein H
chr5_+_174724549 3.39 ENST00000239243.7
ENST00000507785.2
msh homeobox 2
chr10_+_47322450 2.83 ENST00000581492.3
growth differentiation factor 2
chr12_+_80716906 2.79 ENST00000228644.4
myogenic factor 5
chr1_+_160190567 2.77 ENST00000368078.8
calsequestrin 1
chr2_+_233917371 2.48 ENST00000324695.9
ENST00000433712.6
transient receptor potential cation channel subfamily M member 8
chr6_-_87095059 2.17 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr6_-_123636979 2.13 ENST00000662930.1
triadin
chr12_-_16608183 1.95 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr10_+_122192442 1.93 ENST00000514539.5
transforming acidic coiled-coil containing protein 2
chr13_-_35476682 1.91 ENST00000379919.6
mab-21 like 1
chr20_+_57561103 1.91 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr6_-_123636923 1.87 ENST00000334268.9
triadin
chr6_-_123636997 1.81 ENST00000546248.5
triadin
chr11_-_13496018 1.79 ENST00000529816.1
parathyroid hormone
chr8_-_42501224 1.79 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr11_-_13495984 1.77 ENST00000282091.6
parathyroid hormone
chr7_-_13989658 1.70 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr17_-_79950828 1.66 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr4_+_154563003 1.66 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chrX_-_21658324 1.65 ENST00000379499.3
kelch like family member 34
chr10_+_24466487 1.65 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr7_-_73624492 1.63 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr10_-_29736956 1.59 ENST00000674475.1
supervillin
chr4_-_185775271 1.53 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr6_-_123636906 1.52 ENST00000628709.2
triadin
chr4_-_110641920 1.46 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr12_-_102950835 1.42 ENST00000546844.1
phenylalanine hydroxylase
chr20_-_51802433 1.36 ENST00000395997.3
spalt like transcription factor 4
chr5_+_132873660 1.24 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr20_-_51802509 1.18 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr6_-_123636966 1.17 ENST00000542443.5
triadin
chr7_+_1232865 1.16 ENST00000316333.9
UNC homeobox
chr9_+_133636355 1.15 ENST00000393056.8
dopamine beta-hydroxylase
chr15_+_58410543 1.15 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr12_-_16608073 1.11 ENST00000441439.6
LIM domain only 3
chr4_-_185775376 1.08 ENST00000456596.5
ENST00000414724.5
sorbin and SH3 domain containing 2
chr5_+_54455661 1.07 ENST00000302005.3
heat shock protein family B (small) member 3
chr3_-_120682215 1.03 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr12_+_101666203 1.01 ENST00000549608.1
myosin binding protein C1
chrM_+_7586 0.98 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr19_-_55464741 0.97 ENST00000635964.2
chromosome 19 open reading frame 85
chr4_+_150582119 0.95 ENST00000317605.6
mab-21 like 2
chr15_-_53733103 0.94 ENST00000559418.5
WD repeat domain 72
chr4_+_168092530 0.93 ENST00000359299.8
annexin A10
chr21_-_34526850 0.92 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr11_-_16356538 0.92 ENST00000683767.1
SRY-box transcription factor 6
chr6_-_75493629 0.91 ENST00000393004.6
filamin A interacting protein 1
chr4_+_76435216 0.91 ENST00000296043.7
shroom family member 3
chr20_-_7940444 0.90 ENST00000378789.4
hydroxyacid oxidase 1
chr1_+_67685170 0.90 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr17_-_9791586 0.90 ENST00000571134.2
dehydrogenase/reductase 7C
chr5_-_57482808 0.90 ENST00000423391.3
actin beta like 2
chr4_-_185775432 0.90 ENST00000457247.5
ENST00000435480.5
ENST00000425679.5
ENST00000457934.5
sorbin and SH3 domain containing 2
chr3_+_148730100 0.89 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr3_-_120682113 0.88 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr7_+_117020191 0.87 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr12_+_77966204 0.87 ENST00000550503.1
neuron navigator 3
chr12_+_53985138 0.86 ENST00000303460.5
homeobox C10
chr6_-_100464912 0.86 ENST00000369208.8
SIM bHLH transcription factor 1
chr5_-_95961830 0.86 ENST00000513343.1
ENST00000237853.9
elongation factor for RNA polymerase II 2
chr1_+_62597510 0.86 ENST00000371129.4
angiopoietin like 3
chr7_+_74028127 0.86 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr12_+_53985065 0.86 ENST00000515593.1
homeobox C10
chr6_+_160702238 0.84 ENST00000366924.6
ENST00000308192.14
ENST00000418964.1
plasminogen
chr19_+_12938598 0.83 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr11_+_35201083 0.83 ENST00000526553.6
CD44 molecule (Indian blood group)
chr8_-_108787563 0.82 ENST00000297459.4
transmembrane protein 74
chr4_-_185775411 0.80 ENST00000445115.5
ENST00000451701.5
sorbin and SH3 domain containing 2
chr12_+_80707625 0.80 ENST00000228641.4
myogenic factor 6
chrX_+_43656289 0.80 ENST00000338702.4
monoamine oxidase A
chrX_-_32412220 0.79 ENST00000619831.5
dystrophin
chr12_+_20810698 0.79 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr17_-_10549612 0.79 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr4_-_99144238 0.78 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
alcohol dehydrogenase 4 (class II), pi polypeptide
chrX_+_106693838 0.78 ENST00000324342.7
ring finger protein 128
chrX_-_106038721 0.77 ENST00000372563.2
serpin family A member 7
chr6_-_75493773 0.77 ENST00000237172.12
filamin A interacting protein 1
chr16_+_53099100 0.76 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr17_-_10549652 0.75 ENST00000245503.10
myosin heavy chain 2
chr11_+_55723776 0.74 ENST00000641440.1
olfactory receptor family 5 subfamily D member 3 pseudogene
chr1_-_159862648 0.73 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr4_+_70592295 0.73 ENST00000449493.2
ameloblastin
chr18_+_34593312 0.72 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr3_+_2892199 0.72 ENST00000397459.6
contactin 4
chr5_-_181130577 0.72 ENST00000641318.1
ENST00000641367.1
ENST00000642036.1
olfactory receptor family 2 subfamily V member 1
chr17_-_41467386 0.71 ENST00000225899.4
keratin 32
chr9_+_133636378 0.71 ENST00000263611.3
dopamine beta-hydroxylase
chr1_-_93681829 0.70 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr2_+_167135901 0.70 ENST00000628543.2
xin actin binding repeat containing 2
chrM_+_8366 0.70 ENST00000361851.1
mitochondrially encoded ATP synthase membrane subunit 8
chr2_+_210556590 0.70 ENST00000233072.10
ENST00000619804.1
carbamoyl-phosphate synthase 1
chr21_-_34526815 0.70 ENST00000492600.1
regulator of calcineurin 1
chr10_+_92691813 0.69 ENST00000472590.6
hematopoietically expressed homeobox
chr12_-_86256267 0.69 ENST00000620241.4
MGAT4 family member C
chr12_-_86256299 0.69 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr4_-_73620391 0.68 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr9_+_470291 0.68 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr2_+_102761963 0.68 ENST00000640575.2
ENST00000412401.3
transmembrane protein 182
chr14_-_91946989 0.67 ENST00000556154.5
fibulin 5
chr15_+_90868580 0.67 ENST00000268171.8
furin, paired basic amino acid cleaving enzyme
chr4_+_70592253 0.66 ENST00000322937.10
ENST00000613447.4
ameloblastin
chr3_+_2511597 0.65 ENST00000434053.5
contactin 4
chr13_-_75366973 0.65 ENST00000648194.1
TBC1 domain family member 4
chr3_-_151316795 0.63 ENST00000260843.5
G protein-coupled receptor 87
chr5_+_177384430 0.63 ENST00000512593.5
ENST00000324417.6
solute carrier family 34 member 1
chr7_-_107803215 0.63 ENST00000340010.10
ENST00000453332.1
solute carrier family 26 member 3
chr20_+_6007245 0.61 ENST00000378868.4
cardiolipin synthase 1
chr18_+_48539017 0.61 ENST00000256413.8
cap binding complex dependent translation initiation factor
chr11_+_124611420 0.60 ENST00000284288.3
pannexin 3
chr17_+_4788926 0.59 ENST00000331264.8
glycolipid transfer protein domain containing 2
chr5_-_88824334 0.59 ENST00000506716.5
myocyte enhancer factor 2C
chrX_+_106693751 0.59 ENST00000418562.5
ring finger protein 128
chr12_-_16277685 0.58 ENST00000344941.3
solute carrier family 15 member 5
chr5_-_181131169 0.58 ENST00000641551.1
olfactory receptor family 2 subfamily V member 1
chr13_-_37598750 0.58 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr4_-_137532452 0.58 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr4_-_73620629 0.58 ENST00000342081.7
Ras association domain family member 6
chr11_-_123977781 0.56 ENST00000641123.1
olfactory receptor family 10 subfamily S member 1
chr10_-_13707536 0.56 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr7_+_74028066 0.55 ENST00000431562.5
ENST00000320492.11
ENST00000438906.5
elastin
chr17_-_48615261 0.55 ENST00000239144.5
homeobox B8
chr12_-_70637405 0.55 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr8_+_76681208 0.55 ENST00000651372.2
zinc finger homeobox 4
chr2_-_182427014 0.55 ENST00000409365.5
ENST00000351439.9
phosphodiesterase 1A
chr17_-_10549694 0.55 ENST00000622564.4
myosin heavy chain 2
chr5_-_127073467 0.55 ENST00000607731.5
ENST00000509733.7
ENST00000296662.10
ENST00000535381.6
chromosome 5 open reading frame 63
chr2_+_87748087 0.55 ENST00000359481.9
plasminogen like B2
chr1_+_213987929 0.54 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr11_-_124320197 0.54 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr20_+_43558968 0.54 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chr5_-_1882902 0.54 ENST00000231357.7
iroquois homeobox 4
chr17_-_40782544 0.53 ENST00000301656.4
keratin 27
chr14_-_91947383 0.53 ENST00000267620.14
fibulin 5
chr8_+_120125093 0.53 ENST00000297848.8
ENST00000309791.8
collagen type XIV alpha 1 chain
chr6_+_131250375 0.53 ENST00000474850.2
A-kinase anchoring protein 7
chr4_-_99657820 0.53 ENST00000511828.2
chromosome 4 open reading frame 54
chr11_-_36598221 0.53 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chrM_+_10759 0.53 ENST00000361381.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
chr1_+_99646025 0.52 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr21_+_46326288 0.52 ENST00000652508.1
novel protein
chr4_-_73620500 0.52 ENST00000335049.5
Ras association domain family member 6
chrM_+_8489 0.52 ENST00000361899.2
mitochondrially encoded ATP synthase membrane subunit 6
chr12_-_86256376 0.51 ENST00000552435.6
MGAT4 family member C
chr22_-_28094135 0.51 ENST00000442232.1
tetratricopeptide repeat domain 28
chr7_-_84492718 0.51 ENST00000424555.5
semaphorin 3A
chr12_+_26195647 0.50 ENST00000535504.1
sarcospan
chrM_+_9207 0.50 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr11_+_65787056 0.50 ENST00000335987.8
ovo like transcriptional repressor 1
chr12_-_102480552 0.50 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr10_-_33334382 0.49 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr1_-_109392893 0.49 ENST00000633956.1
sortilin 1
chr4_-_173530219 0.48 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr17_-_48613468 0.48 ENST00000498634.2
homeobox B8
chr13_-_85799400 0.48 ENST00000647374.2
SLIT and NTRK like family member 6
chr2_-_87021844 0.47 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr6_+_118548289 0.47 ENST00000357525.6
phospholamban
chr10_+_68109433 0.47 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr6_-_75363003 0.47 ENST00000370020.1
filamin A interacting protein 1
chr4_+_70242583 0.46 ENST00000304954.3
casein kappa
chr1_-_26913964 0.46 ENST00000254227.4
nuclear receptor subfamily 0 group B member 2
chr15_+_67098582 0.46 ENST00000559092.1
ENST00000560175.5
SMAD family member 3
chr4_-_115113614 0.46 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr1_+_186296267 0.46 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
proteoglycan 4
chr12_-_101210232 0.46 ENST00000536262.3
solute carrier family 5 member 8
chr7_+_74027770 0.45 ENST00000445912.5
ENST00000621115.4
elastin
chr2_+_170178136 0.45 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr6_+_54099538 0.45 ENST00000447836.6
muscular LMNA interacting protein
chr18_+_78979811 0.45 ENST00000537592.7
spalt like transcription factor 3
chr17_+_50165990 0.45 ENST00000262018.8
ENST00000344627.10
ENST00000682109.1
ENST00000504073.2
sarcoglycan alpha
chr2_-_216081759 0.45 ENST00000265322.8
peroxisomal trans-2-enoyl-CoA reductase
chr3_-_142029108 0.44 ENST00000497579.5
transcription factor Dp-2
chr18_+_78980181 0.44 ENST00000616649.4
ENST00000575389.6
spalt like transcription factor 3
chr4_-_183322426 0.44 ENST00000541814.1
claudin 24
chrX_+_136169891 0.44 ENST00000449474.5
four and a half LIM domains 1
chr4_+_87650277 0.44 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr3_+_159069252 0.44 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chrX_+_136169833 0.44 ENST00000628032.2
four and a half LIM domains 1
chr7_-_13989891 0.43 ENST00000405218.6
ETS variant transcription factor 1
chr22_-_32464440 0.43 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chrX_+_30235894 0.43 ENST00000620842.1
MAGE family member B3
chr14_-_60649449 0.43 ENST00000645694.3
SIX homeobox 1
chr4_+_94489030 0.43 ENST00000510099.5
PDZ and LIM domain 5
chr11_-_26572254 0.42 ENST00000529533.6
mucin 15, cell surface associated
chr11_-_20160473 0.41 ENST00000524983.3
developing brain homeobox 1
chr10_-_73655984 0.41 ENST00000394810.3
synaptopodin 2 like
chr12_-_27970134 0.41 ENST00000534890.1
parathyroid hormone like hormone
chr5_-_135535955 0.41 ENST00000314744.6
neurogenin 1
chr19_-_12778412 0.41 ENST00000589400.5
ENST00000590839.5
ENST00000592079.5
hook microtubule tethering protein 2
chr1_-_56579555 0.40 ENST00000371250.4
phospholipid phosphatase 3
chr14_-_57493827 0.40 ENST00000526336.1
ENST00000216445.8
coiled-coil domain containing 198
chr8_-_71361860 0.40 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr21_+_30440275 0.40 ENST00000334067.4
keratin associated protein 15-1
chr11_+_20599602 0.40 ENST00000525748.6
solute carrier family 6 member 5
chr1_+_225825346 0.40 ENST00000366837.5
epoxide hydrolase 1
chr14_-_36519679 0.40 ENST00000498187.6
NK2 homeobox 1
chr2_+_200308943 0.39 ENST00000619961.4
spermatogenesis associated serine rich 2 like
chr6_+_54099565 0.39 ENST00000511678.5
muscular LMNA interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.5 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.8 3.4 GO:0051795 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.7 3.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.6 1.9 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.6 1.9 GO:0042309 octopamine biosynthetic process(GO:0006589) homoiothermy(GO:0042309) octopamine metabolic process(GO:0046333)
0.5 1.5 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.4 4.5 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.3 3.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 2.5 GO:0050955 thermoception(GO:0050955)
0.3 0.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.3 0.9 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 0.8 GO:0048561 establishment of organ orientation(GO:0048561)
0.3 4.8 GO:0019532 oxalate transport(GO:0019532)
0.3 1.0 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 3.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 0.7 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.2 0.7 GO:0061011 hepatic duct development(GO:0061011)
0.2 3.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.9 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 0.8 GO:0052047 positive regulation of fibrinolysis(GO:0051919) interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.6 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.5 GO:1901876 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.2 0.9 GO:0061551 trigeminal ganglion development(GO:0061551)
0.1 0.7 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.6 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.4 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.4 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 2.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.6 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 1.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.4 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.6 GO:1990523 bone regeneration(GO:1990523)
0.1 1.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 2.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.5 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.3 GO:0034761 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.5 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.1 4.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.6 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.4 GO:0036233 glycine import(GO:0036233)
0.1 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.4 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 2.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.6 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.4 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.5 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.8 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 1.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.0 GO:0045176 apical protein localization(GO:0045176)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.1 0.4 GO:1903758 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.2 GO:2000851 positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0099545 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.9 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.6 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.8 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.6 GO:0034214 protein hexamerization(GO:0034214)
0.0 1.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0010159 specification of organ position(GO:0010159)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.9 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.1 GO:0002076 osteoblast development(GO:0002076)
0.0 2.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.4 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.5 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 1.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 2.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 1.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.5 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.7 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.0 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 1.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 3.0 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 1.3 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 1.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.9 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 3.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 0.7 GO:0003281 ventricular septum development(GO:0003281)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 3.1 GO:0071953 elastic fiber(GO:0071953)
0.3 1.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.2 7.4 GO:0032982 myosin filament(GO:0032982)
0.2 3.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.8 GO:0044279 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 1.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.5 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.8 GO:0005883 neurofilament(GO:0005883)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005602 complement component C1 complex(GO:0005602)
0.0 3.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838) new growing cell tip(GO:0035841)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 8.0 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 3.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6 1.9 GO:0004411 homogentisate 1,2-dioxygenase activity(GO:0004411)
0.6 1.9 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.6 3.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 0.9 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.3 0.9 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 0.8 GO:1904854 proteasome core complex binding(GO:1904854)
0.3 4.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 1.4 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.4 GO:0019166 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.8 GO:0035276 ethanol binding(GO:0035276)
0.1 0.5 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.1 0.6 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 3.6 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 3.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.4 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.4 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.9 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 2.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 1.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 2.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 10.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 3.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.9 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 3.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 6.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 4.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 4.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)