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Illumina Body Map 2 (GSE30611)

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Results for NR0B1

Z-value: 0.85

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Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
NR0B1
ENSG00000169297.8 nuclear receptor subfamily 0 group B member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR0B1hg38_v1_chrX_-_30309387_30309392-0.602.8e-04Click!

Activity profile of NR0B1 motif

Sorted Z-values of NR0B1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_233636445 3.05 ENST00000344644.9
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr4_+_42397473 2.60 ENST00000319234.5
SHISA3
shisa family member 3
chr2_+_233636502 1.96 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase family 1 member A10
chr1_-_46941464 1.90 ENST00000462347.5
ENST00000371905.1
ENST00000310638.9
CYP4A11
cytochrome P450 family 4 subfamily A member 11
chr2_+_233671879 1.84 ENST00000354728.5
UGT1A9
UDP glucuronosyltransferase family 1 member A9
chr2_+_42048012 1.58 ENST00000294964.6
PKDCC
protein kinase domain containing, cytoplasmic
chr3_+_111859796 1.44 ENST00000393925.7
PHLDB2
pleckstrin homology like domain family B member 2
chr1_-_46941425 1.39 ENST00000371904.8
CYP4A11
cytochrome P450 family 4 subfamily A member 11
chr17_-_7252054 1.26 ENST00000575783.5
ENST00000573600.5
CTDNEP1
CTD nuclear envelope phosphatase 1
chr15_-_64775574 1.22 ENST00000300069.5
RBPMS2
RNA binding protein, mRNA processing factor 2
chr3_+_46883337 1.20 ENST00000313049.9
PTH1R
parathyroid hormone 1 receptor
chr22_+_22895368 1.18 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1
chr3_+_111859180 1.12 ENST00000412622.5
ENST00000431670.7
PHLDB2
pleckstrin homology like domain family B member 2
chr6_-_100464912 1.06 ENST00000369208.8
SIM1
SIM bHLH transcription factor 1
chr11_-_111912871 1.00 ENST00000528628.5
CRYAB
crystallin alpha B
chr6_+_29550407 0.97 ENST00000641137.1
OR2I1P
olfactory receptor family 2 subfamily I member 1 pseudogene
chrX_+_106920393 0.96 ENST00000336803.2
CLDN2
claudin 2
chr1_-_93847150 0.95 ENST00000370244.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr1_+_31413806 0.94 ENST00000536384.2
SERINC2
serine incorporator 2
chr3_+_111859736 0.91 ENST00000478922.1
ENST00000477695.5
PHLDB2
pleckstrin homology like domain family B member 2
chr12_+_56080126 0.91 ENST00000411731.6
ERBB3
erb-b2 receptor tyrosine kinase 3
chr10_-_21174187 0.90 ENST00000417816.2
NEBL
nebulette
chr17_+_78169127 0.88 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr17_-_68601357 0.81 ENST00000592554.2
FAM20A
FAM20A golgi associated secretory pathway pseudokinase
chr22_+_22668286 0.81 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr17_-_7251955 0.79 ENST00000318988.10
CTDNEP1
CTD nuclear envelope phosphatase 1
chr5_+_132369908 0.79 ENST00000435065.6
SLC22A5
solute carrier family 22 member 5
chr17_+_47941562 0.79 ENST00000225573.5
ENST00000434554.7
ENST00000642017.2
PNPO
pyridoxamine 5'-phosphate oxidase
chr3_+_111859284 0.79 ENST00000498699.5
PHLDB2
pleckstrin homology like domain family B member 2
chr1_+_155277414 0.79 ENST00000368358.4
HCN3
hyperpolarization activated cyclic nucleotide gated potassium channel 3
chr17_-_3696198 0.76 ENST00000345901.7
P2RX5
purinergic receptor P2X 5
chr5_+_132369691 0.75 ENST00000245407.8
SLC22A5
solute carrier family 22 member 5
chr19_-_14090695 0.73 ENST00000533683.7
SAMD1
sterile alpha motif domain containing 1
chr17_-_3696133 0.72 ENST00000225328.10
P2RX5
purinergic receptor P2X 5
chr7_-_520216 0.71 ENST00000405692.2
PDGFA
platelet derived growth factor subunit A
chr20_+_37179310 0.71 ENST00000373632.8
ENST00000237530.11
RPN2
ribophorin II
chr19_-_15934521 0.71 ENST00000402119.9
CYP4F11
cytochrome P450 family 4 subfamily F member 11
chrX_+_19343893 0.70 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
PDHA1
pyruvate dehydrogenase E1 subunit alpha 1
chr20_+_37179109 0.70 ENST00000373622.9
RPN2
ribophorin II
chr1_-_147773341 0.70 ENST00000430508.1
ENST00000621517.1
GJA5
gap junction protein alpha 5
chr7_+_90211686 0.67 ENST00000287908.7
ENST00000394621.7
ENST00000394626.5
STEAP2
STEAP2 metalloreductase
chr19_-_15934410 0.66 ENST00000326742.12
CYP4F11
cytochrome P450 family 4 subfamily F member 11
chr6_+_33428223 0.65 ENST00000682587.1
SYNGAP1
synaptic Ras GTPase activating protein 1
chr10_+_73911104 0.65 ENST00000446342.5
ENST00000372764.4
PLAU
plasminogen activator, urokinase
chr7_-_120858303 0.64 ENST00000415871.5
ENST00000430985.1
TSPAN12
tetraspanin 12
chr19_-_45406327 0.64 ENST00000593226.5
ENST00000418234.6
PPP1R13L
protein phosphatase 1 regulatory subunit 13 like
chr6_+_7541612 0.64 ENST00000418664.2
DSP
desmoplakin
chr2_+_47369467 0.62 ENST00000419334.1
EPCAM
epithelial cell adhesion molecule
chr6_-_93419545 0.62 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPHA7
EPH receptor A7
chr17_+_57256514 0.62 ENST00000284073.7
ENST00000674964.1
MSI2
musashi RNA binding protein 2
chr6_+_7541662 0.61 ENST00000379802.8
DSP
desmoplakin
chr8_-_42541578 0.59 ENST00000518384.1
SLC20A2
solute carrier family 20 member 2
chr2_-_164841410 0.58 ENST00000342193.8
ENST00000375458.6
COBLL1
cordon-bleu WH2 repeat protein like 1
chr18_-_35344408 0.58 ENST00000261332.11
ENST00000399061.3
ZNF24
zinc finger protein 24
chr12_+_56080155 0.58 ENST00000267101.8
ERBB3
erb-b2 receptor tyrosine kinase 3
chr11_-_64745331 0.58 ENST00000377489.5
ENST00000354024.7
RASGRP2
RAS guanyl releasing protein 2
chr9_+_105694519 0.57 ENST00000374692.8
ENST00000434214.1
TMEM38B
transmembrane protein 38B
chr4_+_158672266 0.57 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
ETFDH
electron transfer flavoprotein dehydrogenase
chr1_+_25819926 0.57 ENST00000533762.5
ENST00000529116.5
ENST00000474295.5
ENST00000488327.6
ENST00000472643.5
ENST00000374303.7
ENST00000526894.5
ENST00000524618.5
ENST00000374307.9
MTFR1L
mitochondrial fission regulator 1 like
chr9_+_134326435 0.57 ENST00000481739.2
RXRA
retinoid X receptor alpha
chr2_+_26970628 0.56 ENST00000233121.7
ENST00000405074.7
MAPRE3
microtubule associated protein RP/EB family member 3
chr6_+_17393576 0.56 ENST00000229922.7
ENST00000611958.4
CAP2
cyclase associated actin cytoskeleton regulatory protein 2
chr17_-_3696033 0.55 ENST00000551178.5
ENST00000552276.5
ENST00000547178.5
P2RX5
purinergic receptor P2X 5
chr21_+_38809596 0.54 ENST00000456966.1
ETS2
ETS proto-oncogene 2, transcription factor
chr1_-_23484171 0.54 ENST00000336689.8
ENST00000437606.6
ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr14_-_106803221 0.53 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr10_+_122112957 0.51 ENST00000369001.5
TACC2
transforming acidic coiled-coil containing protein 2
chr13_-_33285682 0.51 ENST00000336934.10
STARD13
StAR related lipid transfer domain containing 13
chr1_+_61742418 0.51 ENST00000316485.11
ENST00000371158.6
ENST00000642238.2
ENST00000613764.4
PATJ
PATJ crumbs cell polarity complex component
chr19_-_49119092 0.50 ENST00000408991.4
C19orf73
chromosome 19 open reading frame 73
chr5_-_42811884 0.50 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr16_+_1153202 0.50 ENST00000358590.8
ENST00000638323.1
CACNA1H
calcium voltage-gated channel subunit alpha1 H
chr20_+_58891981 0.49 ENST00000488652.6
ENST00000476935.6
ENST00000492907.6
ENST00000603546.2
GNAS
GNAS complex locus
chr7_+_149714769 0.49 ENST00000486744.3
KRBA1
KRAB-A domain containing 1
chr17_+_7252024 0.49 ENST00000573513.5
ENST00000354429.6
ENST00000574255.5
ENST00000356683.6
ENST00000396627.6
ELP5
elongator acetyltransferase complex subunit 5
chr1_+_25820146 0.49 ENST00000525713.5
ENST00000374301.7
MTFR1L
mitochondrial fission regulator 1 like
chr17_-_7252456 0.48 ENST00000571409.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr12_+_56079843 0.48 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
ERBB3
erb-b2 receptor tyrosine kinase 3
chr17_+_47941506 0.48 ENST00000583599.6
PNPO
pyridoxamine 5'-phosphate oxidase
chr3_+_72996842 0.45 ENST00000495566.1
PPP4R2
protein phosphatase 4 regulatory subunit 2
chr4_-_176792913 0.44 ENST00000618562.2
VEGFC
vascular endothelial growth factor C
chr8_+_26291758 0.44 ENST00000522535.5
ENST00000665949.1
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr1_+_32741779 0.44 ENST00000401073.7
KIAA1522
KIAA1522
chr11_-_1763894 0.43 ENST00000637915.1
ENST00000637815.2
ENST00000236671.7
ENST00000636571.1
ENST00000438213.6
ENST00000637387.1
ENST00000636843.1
ENST00000636397.1
ENST00000636615.1
CTSD
ENSG00000250644.3
cathepsin D
novel protein
chr15_+_44537085 0.43 ENST00000424492.7
EIF3J
eukaryotic translation initiation factor 3 subunit J
chr8_+_64580357 0.43 ENST00000321870.3
BHLHE22
basic helix-loop-helix family member e22
chrX_+_47585212 0.43 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr10_-_13707536 0.43 ENST00000632570.1
ENST00000477221.2
FRMD4A
FERM domain containing 4A
chr15_-_50765656 0.43 ENST00000261854.10
SPPL2A
signal peptide peptidase like 2A
chr7_-_50782853 0.42 ENST00000401949.6
GRB10
growth factor receptor bound protein 10
chrX_-_129654946 0.42 ENST00000429967.3
APLN
apelin
chr2_+_72917489 0.42 ENST00000258106.11
EMX1
empty spiracles homeobox 1
chr10_+_84194527 0.42 ENST00000623527.4
CDHR1
cadherin related family member 1
chr6_+_31158518 0.42 ENST00000376255.4
ENST00000376257.8
TCF19
transcription factor 19
chr20_-_3173516 0.41 ENST00000360342.7
ENST00000645462.1
ENST00000337576.7
LZTS3
leucine zipper tumor suppressor family member 3
chr3_+_188154150 0.41 ENST00000617246.5
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_94927079 0.41 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chrX_+_49171918 0.41 ENST00000376322.7
PLP2
proteolipid protein 2
chr15_+_44537136 0.41 ENST00000261868.10
ENST00000535391.5
EIF3J
eukaryotic translation initiation factor 3 subunit J
chr10_-_17454582 0.40 ENST00000377602.5
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr16_+_58464273 0.40 ENST00000567454.5
NDRG4
NDRG family member 4
chr1_+_212285383 0.40 ENST00000261461.7
PPP2R5A
protein phosphatase 2 regulatory subunit B'alpha
chr12_-_57846686 0.40 ENST00000548823.1
ENST00000398073.7
CTDSP2
CTD small phosphatase 2
chr8_+_94641074 0.39 ENST00000423620.6
ESRP1
epithelial splicing regulatory protein 1
chr3_+_23917170 0.39 ENST00000643707.1
RPL15
ribosomal protein L15
chr19_-_50333504 0.39 ENST00000474951.1
KCNC3
potassium voltage-gated channel subfamily C member 3
chr17_+_7252237 0.38 ENST00000570500.5
ELP5
elongator acetyltransferase complex subunit 5
chr1_+_2556361 0.38 ENST00000355716.5
TNFRSF14
TNF receptor superfamily member 14
chr15_-_78620964 0.38 ENST00000326828.6
CHRNA3
cholinergic receptor nicotinic alpha 3 subunit
chr17_+_70104991 0.38 ENST00000587698.5
ENST00000587892.1
KCNJ16
potassium inwardly rectifying channel subfamily J member 16
chr17_+_7252268 0.37 ENST00000396628.6
ENST00000574993.5
ENST00000573657.5
ELP5
elongator acetyltransferase complex subunit 5
chr5_-_58999885 0.37 ENST00000317118.12
PDE4D
phosphodiesterase 4D
chr1_-_196608359 0.37 ENST00000609185.5
ENST00000451324.6
ENST00000367433.9
ENST00000294725.14
KCNT2
potassium sodium-activated channel subfamily T member 2
chr15_+_40844064 0.37 ENST00000568823.5
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_-_127590707 0.37 ENST00000296210.11
ENST00000355552.8
TPRA1
transmembrane protein adipocyte associated 1
chr1_+_15617415 0.36 ENST00000480945.6
DDI2
DNA damage inducible 1 homolog 2
chr19_+_8364146 0.36 ENST00000301455.7
ENST00000393962.6
ANGPTL4
angiopoietin like 4
chr10_-_17617235 0.36 ENST00000466335.1
HACD1
3-hydroxyacyl-CoA dehydratase 1
chr8_-_141000937 0.36 ENST00000520892.5
PTK2
protein tyrosine kinase 2
chr11_-_117232492 0.36 ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr7_-_108456700 0.36 ENST00000418239.1
NRCAM
neuronal cell adhesion molecule
chr11_-_20160473 0.35 ENST00000524983.3
DBX1
developing brain homeobox 1
chr1_+_153728042 0.34 ENST00000318967.7
ENST00000435409.6
INTS3
integrator complex subunit 3
chr19_-_3573629 0.34 ENST00000592652.1
MFSD12
major facilitator superfamily domain containing 12
chr7_+_90211830 0.34 ENST00000394622.6
ENST00000394632.5
ENST00000426158.1
ENST00000402625.6
STEAP2
STEAP2 metalloreductase
chr6_-_10412879 0.34 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha
chr12_+_110280602 0.33 ENST00000552636.2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
chr4_-_113761927 0.33 ENST00000296402.9
CAMK2D
calcium/calmodulin dependent protein kinase II delta
chr15_+_40844506 0.33 ENST00000568580.5
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_+_9091593 0.33 ENST00000327827.12
C16orf72
chromosome 16 open reading frame 72
chr11_+_64035925 0.33 ENST00000682287.1
FLRT1
fibronectin leucine rich transmembrane protein 1
chr6_+_17393657 0.33 ENST00000493172.5
ENST00000465994.5
CAP2
cyclase associated actin cytoskeleton regulatory protein 2
chr13_-_37869723 0.32 ENST00000426868.6
ENST00000379705.8
ENST00000338947.9
ENST00000355779.6
ENST00000358477.6
ENST00000379673.2
TRPC4
transient receptor potential cation channel subfamily C member 4
chr19_+_49157741 0.32 ENST00000598691.5
TRPM4
transient receptor potential cation channel subfamily M member 4
chr17_-_7252482 0.32 ENST00000572043.5
CTDNEP1
CTD nuclear envelope phosphatase 1
chr17_-_3668640 0.32 ENST00000611779.4
TAX1BP3
Tax1 binding protein 3
chr7_-_100896919 0.31 ENST00000445236.3
ENST00000441605.2
ACHE
acetylcholinesterase (Cartwright blood group)
chr19_-_4722691 0.31 ENST00000598360.5
DPP9
dipeptidyl peptidase 9
chr8_-_101205455 0.31 ENST00000520984.5
ZNF706
zinc finger protein 706
chr12_-_27780236 0.31 ENST00000381273.4
MANSC4
MANSC domain containing 4
chr14_+_51651976 0.31 ENST00000554778.1
FRMD6
FERM domain containing 6
chr3_-_45915596 0.31 ENST00000472635.5
ENST00000492333.5
LZTFL1
leucine zipper transcription factor like 1
chr2_+_54115396 0.31 ENST00000406041.5
ACYP2
acylphosphatase 2
chr11_-_119101814 0.31 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
DPAGT1
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr10_-_77637558 0.31 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr3_+_172040554 0.30 ENST00000336824.8
ENST00000423424.5
FNDC3B
fibronectin type III domain containing 3B
chr2_+_85753984 0.30 ENST00000306279.4
ATOH8
atonal bHLH transcription factor 8
chr6_+_17393607 0.30 ENST00000489374.5
ENST00000378990.6
CAP2
cyclase associated actin cytoskeleton regulatory protein 2
chr11_+_67391975 0.30 ENST00000307980.7
RAD9A
RAD9 checkpoint clamp component A
chr12_+_106774630 0.30 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8B
RIC8 guanine nucleotide exchange factor B
chr22_-_23838987 0.29 ENST00000318109.12
ENST00000404056.1
ENST00000406855.7
ENST00000476077.1
DERL3
derlin 3
chr15_+_40844171 0.29 ENST00000563656.5
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr19_-_2051224 0.29 ENST00000309340.11
ENST00000589534.2
ENST00000250896.9
ENST00000589509.5
MKNK2
MAPK interacting serine/threonine kinase 2
chr16_+_4795357 0.29 ENST00000586005.6
SMIM22
small integral membrane protein 22
chr20_+_297553 0.28 ENST00000500893.4
ZCCHC3
zinc finger CCHC-type containing 3
chr6_+_143060853 0.28 ENST00000447498.5
ENST00000646199.1
ENST00000357847.9
ENST00000629020.2
ENST00000367596.5
ENST00000494282.6
ENST00000275235.8
AIG1
androgen induced 1
chr20_+_58891738 0.28 ENST00000682803.1
GNAS
GNAS complex locus
chr16_+_2019777 0.28 ENST00000566435.4
NPW
neuropeptide W
chr5_+_176365455 0.28 ENST00000310389.6
ARL10
ADP ribosylation factor like GTPase 10
chr5_+_93583212 0.28 ENST00000327111.8
NR2F1
nuclear receptor subfamily 2 group F member 1
chr20_+_3046008 0.28 ENST00000380325.4
MRPS26
mitochondrial ribosomal protein S26
chr3_-_122993232 0.27 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
SEMA5B
semaphorin 5B
chr16_+_19168207 0.27 ENST00000355377.7
ENST00000568115.5
SYT17
synaptotagmin 17
chrX_+_129980965 0.27 ENST00000607874.1
BCORL1
BCL6 corepressor like 1
chr15_+_40844018 0.26 ENST00000344051.8
ENST00000562057.6
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr5_+_96702849 0.26 ENST00000508197.1
CAST
calpastatin
chr7_+_143263412 0.26 ENST00000409500.7
ENST00000443571.6
ENST00000358406.10
ENST00000479303.1
GSTK1
glutathione S-transferase kappa 1
chr16_+_1153098 0.26 ENST00000348261.11
CACNA1H
calcium voltage-gated channel subunit alpha1 H
chr2_+_172084728 0.26 ENST00000361609.4
DLX1
distal-less homeobox 1
chr8_+_22165140 0.26 ENST00000397814.7
ENST00000354870.5
BMP1
bone morphogenetic protein 1
chr12_-_42238261 0.26 ENST00000380790.4
YAF2
YY1 associated factor 2
chr19_+_49119531 0.26 ENST00000334186.9
PPFIA3
PTPRF interacting protein alpha 3
chr14_-_106658251 0.26 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr12_-_6375556 0.26 ENST00000228916.7
SCNN1A
sodium channel epithelial 1 subunit alpha
chr4_-_2756288 0.26 ENST00000510267.5
ENST00000315423.12
ENST00000503235.1
TNIP2
TNFAIP3 interacting protein 2
chr19_-_40348510 0.25 ENST00000582006.5
ENST00000582783.5
C19orf47
chromosome 19 open reading frame 47
chr1_-_153986329 0.25 ENST00000368575.5
RAB13
RAB13, member RAS oncogene family
chr1_+_38991239 0.25 ENST00000432648.8
ENST00000446189.6
ENST00000372984.8
AKIRIN1
akirin 1
chr10_+_84194621 0.25 ENST00000332904.7
CDHR1
cadherin related family member 1
chr15_+_90903731 0.25 ENST00000559965.5
MAN2A2
mannosidase alpha class 2A member 2
chr3_+_172039556 0.24 ENST00000415807.7
ENST00000421757.5
FNDC3B
fibronectin type III domain containing 3B
chr8_-_73746830 0.24 ENST00000524300.6
ENST00000523558.5
ENST00000521210.5
ENST00000355780.9
ENST00000524104.5
ENST00000521736.5
ENST00000521447.5
ENST00000517542.5
ENST00000521451.5
ENST00000521419.5
ENST00000518502.5
STAU2
staufen double-stranded RNA binding protein 2
chr4_+_155758990 0.24 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr12_-_42238323 0.24 ENST00000555248.2
YAF2
YY1 associated factor 2
chr2_-_43595963 0.24 ENST00000405006.8
THADA
THADA armadillo repeat containing
chr2_+_48440757 0.24 ENST00000294952.13
ENST00000281394.8
ENST00000449090.6
PPP1R21
protein phosphatase 1 regulatory subunit 21
chr12_+_52037232 0.24 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4 group A member 1
chrX_+_134796758 0.23 ENST00000414371.6
PABIR3
PABIR family member 3
chr2_-_65432591 0.23 ENST00000356388.9
SPRED2
sprouty related EVH1 domain containing 2
chr6_+_12749419 0.23 ENST00000406205.7
PHACTR1
phosphatase and actin regulator 1
chr10_-_689613 0.23 ENST00000280886.12
ENST00000634311.1
DIP2C
disco interacting protein 2 homolog C
chr8_-_141001192 0.23 ENST00000521059.5
PTK2
protein tyrosine kinase 2
chr3_-_184261547 0.22 ENST00000296238.4
CAMK2N2
calcium/calmodulin dependent protein kinase II inhibitor 2
chr17_-_7207340 0.22 ENST00000650301.1
DLG4
discs large MAGUK scaffold protein 4
chr2_+_27078598 0.22 ENST00000380320.9
EMILIN1
elastin microfibril interfacer 1
chr5_+_96702821 0.22 ENST00000675033.1
CAST
calpastatin
chr19_-_4722767 0.22 ENST00000600621.5
DPP9
dipeptidyl peptidase 9
chr1_+_116909869 0.22 ENST00000393203.3
PTGFRN
prostaglandin F2 receptor inhibitor
chr16_-_1964803 0.21 ENST00000526522.5
ENST00000527302.1
ENST00000529806.5
ENST00000343262.9
ENST00000563194.1
RPS2
ribosomal protein S2
chr19_-_40348375 0.21 ENST00000392035.6
ENST00000683109.1
C19orf47
chromosome 19 open reading frame 47

Network of associatons between targets according to the STRING database.

First level regulatory network of NR0B1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0003095 pressure natriuresis(GO:0003095)
0.8 6.9 GO:0051552 flavone metabolic process(GO:0051552)
0.5 1.5 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.5 1.4 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.3 4.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.7 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.7 GO:0098905 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.2 1.3 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.2 0.8 GO:0044691 tooth eruption(GO:0044691)
0.2 0.6 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.2 0.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 1.6 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.2 0.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.9 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.0 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.4 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1 0.3 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.1 3.0 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 1.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.3 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 1.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.3 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.7 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.4 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.8 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.3 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 2.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:1904000 positive regulation of eating behavior(GO:1904000) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) small intestine smooth muscle contraction(GO:1990770)
0.0 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.4 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 1.9 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 1.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0086017 Purkinje myocyte action potential(GO:0086017)
0.0 0.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.2 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.3 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.5 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 1.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 4.3 GO:0045180 basal cortex(GO:0045180)
0.1 1.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.9 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.0 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:1990742 microvesicle(GO:1990742)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 2.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 2.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.3 1.3 GO:0004733 pyridoxamine-phosphate oxidase activity(GO:0004733)
0.2 1.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 1.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.2 0.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.7 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 2.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 1.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 7.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 2.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.7 GO:0055077 gap junction hemi-channel activity(GO:0055077) gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 1.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
0.1 0.3 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 1.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 1.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.0 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004615 phosphomannomutase activity(GO:0004615)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 3.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.9 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 2.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)