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Illumina Body Map 2 (GSE30611)

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Results for NR1I3

Z-value: 0.37

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.12 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg38_v1_chr1_-_161238196_1612382100.193.0e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_154405326 0.80 ENST00000368485.8
IL6R
interleukin 6 receptor
chr1_+_154405193 0.76 ENST00000622330.4
ENST00000344086.8
IL6R
interleukin 6 receptor
chr1_-_205321737 0.70 ENST00000367157.6
NUAK2
NUAK family kinase 2
chr11_-_61356793 0.61 ENST00000539890.1
CYB561A3
cytochrome b561 family member A3
chr1_+_153357846 0.59 ENST00000368738.4
S100A9
S100 calcium binding protein A9
chr1_+_154405573 0.59 ENST00000512471.1
IL6R
interleukin 6 receptor
chr7_-_56092932 0.58 ENST00000446428.5
ENST00000432123.5
ENST00000297373.7
PHKG1
phosphorylase kinase catalytic subunit gamma 1
chr8_+_11494367 0.55 ENST00000259089.9
ENST00000529894.1
BLK
BLK proto-oncogene, Src family tyrosine kinase
chr8_+_32614361 0.54 ENST00000522569.1
NRG1
neuregulin 1
chr7_-_56092974 0.50 ENST00000452681.6
ENST00000537360.5
PHKG1
phosphorylase kinase catalytic subunit gamma 1
chr14_-_102509713 0.45 ENST00000286918.9
ANKRD9
ankyrin repeat domain 9
chr11_+_62789124 0.43 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr6_+_96521796 0.42 ENST00000369278.5
UFL1
UFM1 specific ligase 1
chrX_-_33211312 0.40 ENST00000420596.5
ENST00000448370.5
DMD
dystrophin
chr14_+_24130659 0.39 ENST00000267426.6
FITM1
fat storage inducing transmembrane protein 1
chr11_-_72041945 0.38 ENST00000543009.5
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_64996963 0.37 ENST00000301887.9
ENST00000534177.1
BATF2
basic leucine zipper ATF-like transcription factor 2
chr6_+_32439866 0.37 ENST00000374982.5
ENST00000395388.7
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr5_-_177510348 0.37 ENST00000377112.8
ENST00000501403.6
ENST00000312943.10
DOK3
docking protein 3
chr12_+_53380639 0.36 ENST00000426431.2
SP1
Sp1 transcription factor
chr5_+_139675471 0.36 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr14_-_102509798 0.36 ENST00000560748.5
ANKRD9
ankyrin repeat domain 9
chr8_-_142752510 0.35 ENST00000359228.4
LYPD2
LY6/PLAUR domain containing 2
chr7_-_73738831 0.35 ENST00000395147.9
ENST00000437775.7
ABHD11
abhydrolase domain containing 11
chr7_-_73738792 0.34 ENST00000222800.8
ENST00000458339.6
ABHD11
abhydrolase domain containing 11
chr16_+_67873036 0.32 ENST00000358933.10
EDC4
enhancer of mRNA decapping 4
chr18_-_23586422 0.32 ENST00000269228.10
NPC1
NPC intracellular cholesterol transporter 1
chr15_+_90266317 0.32 ENST00000622269.1
ENST00000411845.3
ENSG00000275674.1
NGRN
novel protein
neugrin, neurite outgrowth associated
chr1_+_56854764 0.31 ENST00000361249.4
C8A
complement C8 alpha chain
chr19_-_50833187 0.31 ENST00000598673.1
KLK15
kallikrein related peptidase 15
chr1_-_145918485 0.31 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr14_+_22281097 0.31 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr5_-_39270623 0.31 ENST00000512138.1
ENST00000646045.2
FYB1
FYN binding protein 1
chr5_-_177509814 0.31 ENST00000510898.7
ENST00000502885.5
ENST00000506493.5
DOK3
docking protein 3
chr10_+_133160401 0.31 ENST00000684739.1
ENST00000682765.1
ENST00000683144.1
ENST00000683259.1
ENST00000682399.1
ENST00000368571.3
KNDC1
kinase non-catalytic C-lobe domain containing 1
chr11_-_72070050 0.29 ENST00000535087.5
ENST00000535838.5
NUMA1
nuclear mitotic apparatus protein 1
chr3_-_108757407 0.29 ENST00000295755.7
RETNLB
resistin like beta
chr11_+_113908983 0.29 ENST00000537778.5
HTR3B
5-hydroxytryptamine receptor 3B
chr1_-_145918685 0.28 ENST00000369306.8
PEX11B
peroxisomal biogenesis factor 11 beta
chr17_-_29294141 0.28 ENST00000225388.9
NUFIP2
nuclear FMR1 interacting protein 2
chr10_-_80173014 0.27 ENST00000437799.1
ANXA11
annexin A11
chr14_+_21057822 0.27 ENST00000308227.2
RNASE8
ribonuclease A family member 8
chr6_+_108166015 0.26 ENST00000368986.9
NR2E1
nuclear receptor subfamily 2 group E member 1
chr7_-_99784175 0.26 ENST00000651514.1
ENST00000336411.7
ENST00000415003.1
ENST00000354593.6
CYP3A4
cytochrome P450 family 3 subfamily A member 4
chr16_-_66934144 0.26 ENST00000568572.5
CIAO2B
cytosolic iron-sulfur assembly component 2B
chrX_-_111412162 0.25 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
DCX
doublecortin
chr3_-_71753582 0.25 ENST00000295612.7
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr17_-_35063648 0.25 ENST00000394597.7
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr1_-_45542726 0.24 ENST00000676549.1
PRDX1
peroxiredoxin 1
chr17_-_29294107 0.24 ENST00000579665.1
NUFIP2
nuclear FMR1 interacting protein 2
chr19_+_58408735 0.23 ENST00000599238.5
ENST00000322834.7
ZNF584
zinc finger protein 584
chr7_-_99735093 0.23 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P
CYP3A7
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr4_+_70028452 0.23 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
HTN3
histatin 3
chr2_-_68952880 0.23 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr16_-_66934362 0.22 ENST00000567511.1
ENST00000422424.7
CIAO2B
cytosolic iron-sulfur assembly component 2B
chr22_-_23974441 0.22 ENST00000398344.9
ENST00000403754.7
ENST00000430101.2
DDT
D-dopachrome tautomerase
chr7_-_99784248 0.22 ENST00000652018.1
CYP3A4
cytochrome P450 family 3 subfamily A member 4
chr7_+_143381561 0.22 ENST00000354434.8
ZYX
zyxin
chr11_-_83682260 0.22 ENST00000398304.5
ENST00000420775.6
DLG2
discs large MAGUK scaffold protein 2
chr1_+_40817190 0.22 ENST00000443478.3
KCNQ4
potassium voltage-gated channel subfamily Q member 4
chr12_-_118372883 0.22 ENST00000542532.5
ENST00000392533.8
TAOK3
TAO kinase 3
chr12_-_53335737 0.21 ENST00000303846.3
SP7
Sp7 transcription factor
chr11_+_63369779 0.21 ENST00000279178.4
SLC22A9
solute carrier family 22 member 9
chr16_+_67246895 0.21 ENST00000566345.6
SLC9A5
solute carrier family 9 member A5
chr2_-_73269483 0.20 ENST00000295133.9
FBXO41
F-box protein 41
chr12_-_75207998 0.20 ENST00000550433.5
ENST00000548513.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr20_+_36461303 0.19 ENST00000475894.5
DLGAP4
DLG associated protein 4
chr19_+_58408633 0.19 ENST00000306910.9
ENST00000598901.1
ENST00000593920.5
ENST00000596281.1
ZNF584
zinc finger protein 584
chr18_-_21703688 0.19 ENST00000584464.1
ENST00000578270.5
ABHD3
abhydrolase domain containing 3, phospholipase
chr8_-_108787563 0.19 ENST00000297459.4
TMEM74
transmembrane protein 74
chr19_+_51478533 0.19 ENST00000396477.4
CEACAM18
CEA cell adhesion molecule 18
chr5_+_139675436 0.19 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr2_+_70087468 0.18 ENST00000303577.7
PCBP1
poly(rC) binding protein 1
chr9_+_34179005 0.18 ENST00000625521.2
ENST00000379186.8
ENST00000297661.9
ENST00000626262.2
UBAP1
ubiquitin associated protein 1
chr7_+_143381907 0.18 ENST00000392910.6
ZYX
zyxin
chr11_-_89065969 0.18 ENST00000305447.5
GRM5
glutamate metabotropic receptor 5
chr9_+_5450503 0.18 ENST00000381573.8
ENST00000381577.4
CD274
CD274 molecule
chr6_+_70566892 0.18 ENST00000370474.4
SDHAF4
succinate dehydrogenase complex assembly factor 4
chrX_+_48786578 0.17 ENST00000376670.9
GATA1
GATA binding protein 1
chr3_+_52316319 0.17 ENST00000420323.7
DNAH1
dynein axonemal heavy chain 1
chr1_+_152947154 0.17 ENST00000636302.1
SPRR5
small proline rich protein 5
chr11_-_47848539 0.17 ENST00000526870.1
NUP160
nucleoporin 160
chr10_-_80172839 0.16 ENST00000265447.8
ANXA11
annexin A11
chr5_-_136193143 0.16 ENST00000607574.2
SMIM32
small integral membrane protein 32
chr15_-_42051190 0.16 ENST00000399518.3
PLA2G4E
phospholipase A2 group IVE
chr1_+_160127672 0.15 ENST00000447527.1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr16_+_2988256 0.15 ENST00000573315.2
LINC00514
long intergenic non-protein coding RNA 514
chr1_-_151146643 0.15 ENST00000613223.1
SEMA6C
semaphorin 6C
chr14_-_77320813 0.15 ENST00000682467.1
POMT2
protein O-mannosyltransferase 2
chr3_-_56468346 0.14 ENST00000288221.11
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr10_+_102503956 0.13 ENST00000369902.8
SUFU
SUFU negative regulator of hedgehog signaling
chr16_+_527698 0.13 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
CAPN15
calpain 15
chr1_+_43935807 0.13 ENST00000438616.3
ARTN
artemin
chr1_+_81699665 0.13 ENST00000359929.7
ADGRL2
adhesion G protein-coupled receptor L2
chr12_-_108598002 0.12 ENST00000549447.1
TMEM119
transmembrane protein 119
chr1_-_225428813 0.12 ENST00000338179.6
ENST00000425080.1
LBR
lamin B receptor
chr14_-_77320741 0.12 ENST00000682795.1
ENST00000682247.1
POMT2
protein O-mannosyltransferase 2
chr19_-_48390847 0.12 ENST00000597017.5
KDELR1
KDEL endoplasmic reticulum protein retention receptor 1
chr1_+_32465046 0.12 ENST00000609129.2
ZBTB8B
zinc finger and BTB domain containing 8B
chr11_-_7963646 0.12 ENST00000328600.3
NLRP10
NLR family pyrin domain containing 10
chr11_+_933553 0.11 ENST00000534485.5
AP2A2
adaptor related protein complex 2 subunit alpha 2
chr14_+_52707192 0.11 ENST00000445930.7
ENST00000555339.5
ENST00000556813.1
PSMC6
proteasome 26S subunit, ATPase 6
chr14_-_21537064 0.11 ENST00000541965.1
SALL2
spalt like transcription factor 2
chr11_-_61357239 0.11 ENST00000536915.5
CYB561A3
cytochrome b561 family member A3
chr1_+_27392612 0.11 ENST00000374024.4
GPR3
G protein-coupled receptor 3
chr7_-_143882808 0.11 ENST00000460532.5
ENST00000491908.1
TCAF1
TRPM8 channel associated factor 1
chr14_-_21536884 0.11 ENST00000546363.5
SALL2
spalt like transcription factor 2
chr6_+_33454543 0.10 ENST00000621915.1
ENST00000395064.3
ZBTB9
zinc finger and BTB domain containing 9
chr10_+_86654581 0.10 ENST00000443292.1
OPN4
opsin 4
chr11_-_57322300 0.10 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1
chr6_-_31541937 0.10 ENST00000456662.5
ENST00000431908.5
ENST00000456976.5
ENST00000428450.5
ENST00000418897.5
ENST00000396172.6
ENST00000419020.1
ENST00000428098.5
DDX39B
DExD-box helicase 39B
chr19_-_6604083 0.10 ENST00000597430.2
CD70
CD70 molecule
chr12_-_21403637 0.10 ENST00000450590.5
ENST00000453443.5
SLCO1A2
solute carrier organic anion transporter family member 1A2
chr8_-_52714414 0.09 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1CC1
RB1 inducible coiled-coil 1
chr1_-_9026386 0.09 ENST00000400906.2
SLC2A7
solute carrier family 2 member 7
chr14_-_77320855 0.09 ENST00000556394.2
ENST00000261534.9
POMT2
protein O-mannosyltransferase 2
chr13_-_94479671 0.09 ENST00000377028.10
ENST00000446125.1
DCT
dopachrome tautomerase
chr11_-_47848313 0.09 ENST00000530326.5
ENST00000528071.5
NUP160
nucleoporin 160
chr11_-_89065945 0.09 ENST00000393294.3
GRM5
glutamate metabotropic receptor 5
chr16_-_74985070 0.09 ENST00000616369.4
ENST00000262144.11
WDR59
WD repeat domain 59
chr2_-_39120383 0.08 ENST00000395038.6
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1
chr1_-_21298988 0.08 ENST00000481130.6
ECE1
endothelin converting enzyme 1
chr1_-_155187272 0.08 ENST00000473363.3
ENSG00000273088.2
novel protein
chr6_-_34146080 0.08 ENST00000538487.7
ENST00000374181.8
GRM4
glutamate metabotropic receptor 4
chr19_+_54200849 0.08 ENST00000626547.2
ENST00000302907.9
ENST00000391752.5
ENST00000402367.5
ENST00000391751.7
RPS9
ribosomal protein S9
chr17_-_58219227 0.07 ENST00000581180.2
ENST00000313863.11
ENST00000393119.7
ENST00000678463.1
ENST00000676787.1
ENST00000580127.6
ENST00000585134.2
ENST00000581761.6
MKS1
MKS transition zone complex subunit 1
chr4_+_37244735 0.07 ENST00000309447.6
NWD2
NACHT and WD repeat domain containing 2
chr2_-_86563349 0.07 ENST00000409727.5
CHMP3
charged multivesicular body protein 3
chr1_-_158426237 0.07 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr11_-_47848467 0.07 ENST00000378460.6
NUP160
nucleoporin 160
chr2_-_86563382 0.07 ENST00000263856.9
CHMP3
charged multivesicular body protein 3
chr11_-_31812171 0.07 ENST00000639409.1
ENST00000640975.1
PAX6
paired box 6
chr17_+_28506233 0.07 ENST00000577936.1
FOXN1
forkhead box N1
chr2_-_227164194 0.07 ENST00000396625.5
COL4A4
collagen type IV alpha 4 chain
chr11_+_197303 0.06 ENST00000342593.6
ODF3
outer dense fiber of sperm tails 3
chr11_-_61357304 0.06 ENST00000542361.5
CYB561A3
cytochrome b561 family member A3
chr19_-_48637338 0.05 ENST00000601104.1
ENST00000222122.10
DBP
D-box binding PAR bZIP transcription factor
chr19_+_54201122 0.05 ENST00000391753.6
ENST00000441429.1
RPS9
ribosomal protein S9
chr4_-_81214960 0.05 ENST00000395578.3
ENST00000628926.1
PRKG2
protein kinase cGMP-dependent 2
chr17_-_40648646 0.05 ENST00000643318.1
SMARCE1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr2_-_68871382 0.04 ENST00000295379.2
BMP10
bone morphogenetic protein 10
chr19_-_45792755 0.04 ENST00000377735.7
ENST00000270223.7
DMWD
DM1 locus, WD repeat containing
chr10_+_18400562 0.04 ENST00000377315.5
ENST00000650685.1
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr1_+_44808482 0.03 ENST00000450269.5
ENST00000409335.6
BTBD19
BTB domain containing 19
chr2_-_86563470 0.03 ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr5_+_53560627 0.03 ENST00000296684.10
ENST00000506765.1
NDUFS4
NADH:ubiquinone oxidoreductase subunit S4
chr9_+_37486006 0.03 ENST00000377792.3
POLR1E
RNA polymerase I subunit E
chr18_-_21704763 0.03 ENST00000580981.5
ENST00000289119.7
ABHD3
abhydrolase domain containing 3, phospholipase
chrX_+_129738942 0.03 ENST00000371106.4
XPNPEP2
X-prolyl aminopeptidase 2
chr14_+_52707178 0.03 ENST00000612399.4
PSMC6
proteasome 26S subunit, ATPase 6
chr14_-_21536928 0.02 ENST00000613414.4
SALL2
spalt like transcription factor 2
chr16_+_30699155 0.02 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chr16_-_46689145 0.02 ENST00000299138.12
VPS35
VPS35 retromer complex component
chr1_+_43337803 0.01 ENST00000372470.9
ENST00000413998.7
MPL
MPL proto-oncogene, thrombopoietin receptor
chr12_+_53300027 0.01 ENST00000549488.5
MYG1
MYG1 exonuclease
chr1_-_151146611 0.01 ENST00000341697.7
ENST00000368914.8
SEMA6C
semaphorin 6C
chr3_+_122384167 0.01 ENST00000232125.9
ENST00000477892.5
ENST00000469967.1
FAM162A
family with sequence similarity 162 member A

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:0100057 regulation of phenotypic switching by transcription from RNA polymerase II promoter(GO:0100057) regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.1 0.5 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.7 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0030221 basophil differentiation(GO:0030221)
0.1 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.4 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 0.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.5 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.3 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.1 GO:0097536 thymus epithelium morphogenesis(GO:0097536)
0.0 0.1 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.4 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.7 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.7 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.2 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.5 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers