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Illumina Body Map 2 (GSE30611)

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Results for NR2C1

Z-value: 1.30

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Transcription factors associated with NR2C1

Gene Symbol Gene ID Gene Info
NR2C1
ENSG00000120798.17 nuclear receptor subfamily 2 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C1hg38_v1_chr12_-_95073580_95073641-0.336.5e-02Click!

Activity profile of NR2C1 motif

Sorted Z-values of NR2C1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_229434086 11.97 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
ACTA1
actin alpha 1, skeletal muscle
chr17_+_39665340 8.69 ENST00000578283.1
ENST00000309889.3
TCAP
titin-cap
chr16_-_4242068 6.20 ENST00000399609.7
SRL
sarcalumenin
chr1_-_982086 5.46 ENST00000341290.6
PERM1
PPARGC1 and ESRR induced regulator, muscle 1
chr17_+_4950147 4.83 ENST00000522301.5
ENO3
enolase 3
chr12_+_48106094 4.80 ENST00000546755.5
ENST00000549366.5
ENST00000642730.1
ENST00000552792.5
PFKM
phosphofructokinase, muscle
chr14_+_104745960 4.74 ENST00000556623.1
ENST00000555674.1
ADSS1
adenylosuccinate synthase 1
chr6_-_159727324 4.57 ENST00000401980.3
ENST00000545162.5
SOD2
superoxide dismutase 2
chr19_+_16661121 4.44 ENST00000187762.7
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr6_-_159726871 4.39 ENST00000535561.5
SOD2
superoxide dismutase 2
chr19_-_48363914 4.27 ENST00000377431.6
ENST00000293261.8
TMEM143
transmembrane protein 143
chr1_+_160127672 3.72 ENST00000447527.1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr9_-_35685462 3.63 ENST00000607559.1
TPM2
tropomyosin 2
chr19_-_48364034 3.59 ENST00000435956.7
TMEM143
transmembrane protein 143
chr22_+_31122923 3.07 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr11_+_10450627 2.93 ENST00000396554.7
ENST00000524866.5
AMPD3
adenosine monophosphate deaminase 3
chr3_+_37243333 2.91 ENST00000431105.1
GOLGA4
golgin A4
chr4_-_110623051 2.66 ENST00000557119.2
ENST00000644743.1
PITX2
paired like homeodomain 2
chr15_-_82806054 2.63 ENST00000541889.1
ENST00000334574.12
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr12_+_109139397 2.54 ENST00000377854.9
ENST00000377848.7
ACACB
acetyl-CoA carboxylase beta
chr11_+_10450289 2.53 ENST00000444303.6
AMPD3
adenosine monophosphate deaminase 3
chr18_+_7231125 2.44 ENST00000383467.2
LRRC30
leucine rich repeat containing 30
chr17_+_14069489 2.37 ENST00000429152.6
ENST00000261643.8
COX10
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
chr6_+_133240587 2.34 ENST00000452339.6
EYA4
EYA transcriptional coactivator and phosphatase 4
chr1_+_43946905 2.04 ENST00000372343.8
IPO13
importin 13
chr11_+_112025367 2.02 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
DLAT
dihydrolipoamide S-acetyltransferase
chr3_+_37243177 2.02 ENST00000361924.6
ENST00000444882.5
ENST00000356847.8
ENST00000617480.4
ENST00000450863.6
ENST00000429018.5
GOLGA4
golgin A4
chr3_+_159839847 2.00 ENST00000445224.6
SCHIP1
schwannomin interacting protein 1
chr10_+_62049211 2.00 ENST00000309334.5
ARID5B
AT-rich interaction domain 5B
chr8_-_143953845 1.81 ENST00000354958.6
PLEC
plectin
chr11_+_64306227 1.76 ENST00000405666.5
ENST00000468670.2
ESRRA
estrogen related receptor alpha
chr2_+_201451711 1.73 ENST00000194530.8
ENST00000392249.6
STRADB
STE20 related adaptor beta
chr8_-_144063951 1.72 ENST00000567871.2
OPLAH
5-oxoprolinase, ATP-hydrolysing
chr10_+_24466487 1.70 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr3_+_155083889 1.69 ENST00000680282.1
MME
membrane metalloendopeptidase
chr11_+_94768331 1.66 ENST00000317829.12
ENST00000433060.3
AMOTL1
angiomotin like 1
chr4_+_158672266 1.54 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
ETFDH
electron transfer flavoprotein dehydrogenase
chr3_+_155083523 1.53 ENST00000680057.1
MME
membrane metalloendopeptidase
chrX_-_112840815 1.52 ENST00000304758.5
ENST00000371959.9
AMOT
angiomotin
chr15_+_90906741 1.45 ENST00000557865.5
MAN2A2
mannosidase alpha class 2A member 2
chr15_+_65076744 1.42 ENST00000432196.5
KBTBD13
kelch repeat and BTB domain containing 13
chrX_+_38561530 1.42 ENST00000378482.7
ENST00000286824.6
TSPAN7
tetraspanin 7
chr16_+_83899079 1.41 ENST00000262430.6
MLYCD
malonyl-CoA decarboxylase
chr9_-_33402449 1.28 ENST00000377425.8
AQP7
aquaporin 7
chr14_-_72894091 1.26 ENST00000556509.6
DPF3
double PHD fingers 3
chr3_-_58627596 1.23 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr8_+_95024977 1.19 ENST00000396124.9
NDUFAF6
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr15_-_43571497 1.18 ENST00000439195.5
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr5_+_1801387 1.16 ENST00000274137.10
ENST00000469176.1
NDUFS6
NADH:ubiquinone oxidoreductase subunit S6
chr14_-_77320741 1.13 ENST00000682795.1
ENST00000682247.1
POMT2
protein O-mannosyltransferase 2
chr8_+_12951583 1.09 ENST00000528753.2
TRMT9B
tRNA methyltransferase 9B (putative)
chr6_+_33204645 1.08 ENST00000374662.4
HSD17B8
hydroxysteroid 17-beta dehydrogenase 8
chr6_+_159727561 1.08 ENST00000631126.2
ENST00000337387.4
WTAP
WT1 associated protein
chr16_-_88686453 1.03 ENST00000332281.6
SNAI3
snail family transcriptional repressor 3
chr6_+_43770202 1.03 ENST00000372067.8
ENST00000672860.2
VEGFA
vascular endothelial growth factor A
chr3_-_58627567 1.01 ENST00000649301.1
FAM107A
family with sequence similarity 107 member A
chr4_+_158672237 0.98 ENST00000682734.1
ETFDH
electron transfer flavoprotein dehydrogenase
chr8_+_12951325 0.97 ENST00000400069.7
TRMT9B
tRNA methyltransferase 9B (putative)
chr9_-_33402551 0.97 ENST00000297988.6
ENST00000624075.3
ENST00000625032.1
ENST00000625109.3
AQP7
aquaporin 7
chr19_-_50786139 0.96 ENST00000562076.2
ENSG00000261341.7
novel protein
chr12_-_124388811 0.90 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr10_-_61001430 0.90 ENST00000357917.4
RHOBTB1
Rho related BTB domain containing 1
chr14_-_77320813 0.87 ENST00000682467.1
POMT2
protein O-mannosyltransferase 2
chr19_-_43198079 0.86 ENST00000597374.5
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr22_-_38455199 0.86 ENST00000303592.3
KCNJ4
potassium inwardly rectifying channel subfamily J member 4
chr14_-_21024092 0.82 ENST00000554398.5
NDRG2
NDRG family member 2
chr2_-_213150236 0.81 ENST00000442445.1
ENST00000342002.6
IKZF2
IKAROS family zinc finger 2
chr12_-_53335737 0.81 ENST00000303846.3
SP7
Sp7 transcription factor
chr20_-_45857196 0.80 ENST00000457981.5
ENST00000426915.1
ENST00000217455.9
ACOT8
acyl-CoA thioesterase 8
chr14_-_77320855 0.79 ENST00000556394.2
ENST00000261534.9
POMT2
protein O-mannosyltransferase 2
chr16_-_11915991 0.77 ENST00000420576.6
GSPT1
G1 to S phase transition 1
chr6_+_31547560 0.76 ENST00000376148.9
ENST00000376145.8
NFKBIL1
NFKB inhibitor like 1
chr11_-_26722051 0.76 ENST00000396005.8
SLC5A12
solute carrier family 5 member 12
chr14_+_73569115 0.75 ENST00000622407.4
ENST00000238651.10
ACOT2
acyl-CoA thioesterase 2
chr22_+_29767351 0.74 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr12_-_53676072 0.74 ENST00000549748.2
ENST00000394349.9
ATP5MC2
ATP synthase membrane subunit c locus 2
chr7_+_143052341 0.73 ENST00000418316.2
OR6V1
olfactory receptor family 6 subfamily V member 1
chr1_+_61082398 0.72 ENST00000664149.1
NFIA
nuclear factor I A
chr3_+_150546765 0.70 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
EIF2A
eukaryotic translation initiation factor 2A
chr5_+_171420016 0.70 ENST00000675071.1
ENSG00000288639.1
novel protein
chr13_-_33185994 0.70 ENST00000255486.8
STARD13
StAR related lipid transfer domain containing 13
chr3_+_172126972 0.70 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr2_+_201071984 0.69 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NDUFB3
NADH:ubiquinone oxidoreductase subunit B3
chr12_-_53676314 0.69 ENST00000549164.5
ATP5MC2
ATP synthase membrane subunit c locus 2
chr3_+_150546671 0.68 ENST00000487799.5
EIF2A
eukaryotic translation initiation factor 2A
chr14_+_73537135 0.67 ENST00000311148.9
ACOT1
acyl-CoA thioesterase 1
chr6_+_159726998 0.66 ENST00000614346.4
WTAP
WT1 associated protein
chr8_-_80030232 0.66 ENST00000518271.1
ENST00000276585.9
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr15_-_82262660 0.62 ENST00000557844.1
ENST00000359445.7
ENST00000268206.12
EFL1
elongation factor like GTPase 1
chr6_+_10585748 0.61 ENST00000265012.5
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr11_-_64245816 0.60 ENST00000542235.1
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr1_+_215081793 0.58 ENST00000478774.5
KCNK2
potassium two pore domain channel subfamily K member 2
chr4_-_185740211 0.58 ENST00000452351.5
SORBS2
sorbin and SH3 domain containing 2
chr12_-_108826161 0.56 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr19_+_50790415 0.55 ENST00000270593.2
ACP4
acid phosphatase 4
chr1_-_54623518 0.55 ENST00000302250.7
ENST00000371304.2
FAM151A
family with sequence similarity 151 member A
chr16_-_11915878 0.55 ENST00000439887.6
ENST00000434724.7
GSPT1
G1 to S phase transition 1
chr17_-_41586887 0.54 ENST00000167586.7
KRT14
keratin 14
chr2_-_213150387 0.54 ENST00000433134.5
IKZF2
IKAROS family zinc finger 2
chr3_+_184186023 0.54 ENST00000429586.6
ENST00000292808.5
ABCF3
ATP binding cassette subfamily F member 3
chr19_-_35812838 0.53 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr2_-_201451446 0.53 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr14_+_77320996 0.52 ENST00000361389.8
ENST00000554279.5
ENST00000557639.5
ENST00000349555.7
ENST00000216465.10
ENST00000556627.5
ENST00000557053.5
GSTZ1
glutathione S-transferase zeta 1
chr11_-_26721999 0.52 ENST00000280467.10
SLC5A12
solute carrier family 5 member 12
chr11_+_65530639 0.51 ENST00000279270.10
SCYL1
SCY1 like pseudokinase 1
chr4_-_84499281 0.49 ENST00000295886.5
NKX6-1
NK6 homeobox 1
chr22_-_31140494 0.48 ENST00000215885.4
PLA2G3
phospholipase A2 group III
chr6_+_54307856 0.48 ENST00000370869.7
TINAG
tubulointerstitial nephritis antigen
chr19_+_11239602 0.47 ENST00000252453.12
ANGPTL8
angiopoietin like 8
chr20_+_19889502 0.47 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr8_-_80029904 0.46 ENST00000521434.5
ENST00000519120.1
ENST00000520946.1
MRPS28
mitochondrial ribosomal protein S28
chr1_+_44674728 0.45 ENST00000453711.1
ARMH1
armadillo like helical domain containing 1
chr18_+_56651335 0.45 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WDR7
WD repeat domain 7
chr1_-_226186673 0.42 ENST00000366812.6
ACBD3
acyl-CoA binding domain containing 3
chr2_+_108621260 0.41 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr14_-_21023954 0.41 ENST00000554094.5
NDRG2
NDRG family member 2
chr1_-_145707345 0.40 ENST00000417171.6
PDZK1
PDZ domain containing 1
chr19_-_4066892 0.39 ENST00000322357.9
ZBTB7A
zinc finger and BTB domain containing 7A
chr19_-_35563653 0.36 ENST00000262623.4
ATP4A
ATPase H+/K+ transporting subunit alpha
chr12_-_42237727 0.36 ENST00000548917.1
YAF2
YY1 associated factor 2
chr3_-_126517764 0.34 ENST00000290868.7
UROC1
urocanate hydratase 1
chr19_-_50968775 0.34 ENST00000391808.5
KLK6
kallikrein related peptidase 6
chrX_-_50470818 0.34 ENST00000611977.2
DGKK
diacylglycerol kinase kappa
chr22_+_46762677 0.33 ENST00000355704.7
TBC1D22A
TBC1 domain family member 22A
chr2_+_209771972 0.33 ENST00000439458.5
ENST00000272845.10
UNC80
unc-80 homolog, NALCN channel complex subunit
chr22_+_46762617 0.33 ENST00000380995.5
ENST00000337137.9
ENST00000407381.7
TBC1D22A
TBC1 domain family member 22A
chr11_+_22668101 0.32 ENST00000630668.2
ENST00000278187.7
GAS2
growth arrest specific 2
chr10_-_102056116 0.31 ENST00000370033.9
ENST00000311122.5
ARMH3
armadillo like helical domain containing 3
chr14_+_21768482 0.31 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6
chr2_-_218269619 0.31 ENST00000447885.1
ENST00000420660.5
AAMP
angio associated migratory cell protein
chr2_+_33476640 0.29 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RASGRP3
RAS guanyl releasing protein 3
chr1_-_22963178 0.29 ENST00000618559.1
LACTBL1
lactamase beta like 1
chr12_-_118372883 0.29 ENST00000542532.5
ENST00000392533.8
TAOK3
TAO kinase 3
chr8_-_80029826 0.29 ENST00000519386.5
MRPS28
mitochondrial ribosomal protein S28
chr13_+_21140514 0.28 ENST00000382533.8
ENST00000621421.4
SAP18
Sin3A associated protein 18
chr3_-_113746059 0.27 ENST00000477813.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr1_+_61082702 0.26 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
NFIA
nuclear factor I A
chr2_-_218568291 0.26 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
USP37
ubiquitin specific peptidase 37
chr1_-_145707387 0.25 ENST00000451928.6
PDZK1
PDZ domain containing 1
chr11_-_134411854 0.25 ENST00000392580.5
B3GAT1
beta-1,3-glucuronyltransferase 1
chr11_-_64246190 0.25 ENST00000392210.6
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr3_-_113746218 0.24 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr11_-_65662419 0.23 ENST00000527874.1
RELA
RELA proto-oncogene, NF-kB subunit
chr2_+_74513441 0.23 ENST00000621092.1
TLX2
T cell leukemia homeobox 2
chr3_-_126517745 0.23 ENST00000383579.3
UROC1
urocanate hydratase 1
chr3_-_50567711 0.23 ENST00000357203.8
C3orf18
chromosome 3 open reading frame 18
chr3_-_113746185 0.22 ENST00000616174.1
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr12_-_42238203 0.21 ENST00000327791.8
ENST00000534854.7
YAF2
YY1 associated factor 2
chr11_-_62672255 0.21 ENST00000528862.2
LBHD1
LBH domain containing 1
chr20_-_59032292 0.20 ENST00000395663.1
ENST00000243997.8
ENST00000395659.1
ATP5F1E
ATP synthase F1 subunit epsilon
chr1_-_19923617 0.20 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr13_+_21140774 0.19 ENST00000450573.5
ENST00000467636.1
SAP18
Sin3A associated protein 18
chr11_+_7573905 0.19 ENST00000529575.5
PPFIBP2
PPFIA binding protein 2
chr22_+_41381923 0.18 ENST00000266304.9
TEF
TEF transcription factor, PAR bZIP family member
chr19_-_40750302 0.17 ENST00000598485.6
ENST00000378313.7
ENST00000470681.5
C19orf54
chromosome 19 open reading frame 54
chr1_-_44141631 0.17 ENST00000634670.1
KLF18
Kruppel like factor 18
chr2_-_42361149 0.15 ENST00000468711.5
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr17_-_41047267 0.15 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr11_-_73976952 0.14 ENST00000545212.1
UCP2
uncoupling protein 2
chr4_-_75673112 0.14 ENST00000395719.7
ENST00000677489.1
G3BP2
G3BP stress granule assembly factor 2
chr4_-_75673139 0.13 ENST00000677566.1
ENST00000503660.5
ENST00000677060.1
ENST00000678552.1
G3BP2
G3BP stress granule assembly factor 2
chr1_-_27366917 0.13 ENST00000357582.3
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr20_+_48921701 0.13 ENST00000371917.5
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2
chr3_+_179347686 0.12 ENST00000471841.6
MFN1
mitofusin 1
chr13_+_21140572 0.12 ENST00000607003.5
ENST00000492245.5
SAP18
Sin3A associated protein 18
chr18_+_56651385 0.11 ENST00000615645.4
WDR7
WD repeat domain 7
chr19_+_6464491 0.08 ENST00000308243.7
CRB3
crumbs cell polarity complex component 3
chr6_-_142147122 0.07 ENST00000258042.2
NMBR
neuromedin B receptor
chrX_-_139204275 0.07 ENST00000441825.8
FGF13
fibroblast growth factor 13
chr21_+_44012296 0.06 ENST00000291574.9
ENST00000380221.7
TRAPPC10
trafficking protein particle complex 10
chr17_+_73193029 0.06 ENST00000299886.9
ENST00000438720.7
COG1
component of oligomeric golgi complex 1
chr3_+_42856021 0.06 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr8_-_92103270 0.06 ENST00000518832.1
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr1_+_61082553 0.05 ENST00000403491.8
ENST00000371187.7
NFIA
nuclear factor I A
chr4_-_75672868 0.05 ENST00000678123.1
ENST00000678578.1
ENST00000677876.1
ENST00000676839.1
ENST00000678265.1
G3BP2
G3BP stress granule assembly factor 2
chr10_-_71719772 0.01 ENST00000441508.4
C10orf105
chromosome 10 open reading frame 105
chr11_-_72703385 0.01 ENST00000452383.2
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr4_-_98143416 0.01 ENST00000295268.4
STPG2
sperm tail PG-rich repeat containing 2
chr12_+_51907478 0.01 ENST00000388922.9
ACVRL1
activin A receptor like type 1
chr5_+_171419635 0.01 ENST00000274625.6
FGF18
fibroblast growth factor 18

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.0 GO:0090131 mesenchyme migration(GO:0090131)
1.8 9.0 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
1.2 3.7 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
1.1 8.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.1 3.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.9 2.7 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.8 4.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.8 5.5 GO:0006196 AMP catabolic process(GO:0006196)
0.5 3.9 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.4 1.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 2.8 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.3 1.0 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 3.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.7 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 2.2 GO:0015793 glycerol transport(GO:0015793)
0.2 0.6 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 0.9 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 1.4 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 4.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 5.5 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 2.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0072560 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) type B pancreatic cell maturation(GO:0072560)
0.1 1.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 2.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 2.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.5 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.6 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 2.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 4.8 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.1 1.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.2 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.7 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 1.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 3.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 3.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 2.0 GO:0016577 histone demethylation(GO:0016577)
0.0 1.0 GO:0072189 ureter development(GO:0072189)
0.0 1.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 1.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.7 GO:0015879 carnitine transport(GO:0015879)
0.0 1.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.5 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 6.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 1.3 GO:0018444 translation release factor complex(GO:0018444)
0.4 4.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 15.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.3 1.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 1.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 3.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 3.1 GO:0070069 cytochrome complex(GO:0070069)
0.1 2.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 4.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 3.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 1.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 9.3 GO:0030018 Z disc(GO:0030018)
0.0 3.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 3.9 GO:0005903 brush border(GO:0005903)
0.0 4.3 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 10.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 3.8 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.7 GO:0051373 FATZ binding(GO:0051373)
0.9 9.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 2.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 5.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 4.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.5 2.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.4 4.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 2.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.4 2.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 1.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.3 2.2 GO:0015254 glycerol channel activity(GO:0015254)
0.3 1.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.3 0.8 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.2 0.7 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.2 3.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.2 2.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 3.7 GO:1990239 steroid hormone binding(GO:1990239)
0.2 1.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 12.0 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 1.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 4.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.7 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.0 6.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 2.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.8 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 2.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.5 GO:0008238 exopeptidase activity(GO:0008238)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.7 PID RHOA PATHWAY RhoA signaling pathway
0.1 7.6 PID FOXO PATHWAY FoxO family signaling
0.1 3.4 ST GAQ PATHWAY G alpha q Pathway
0.1 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 12.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 9.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 3.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 3.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells