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Illumina Body Map 2 (GSE30611)

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Results for NR2E1

Z-value: 0.69

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.12 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg38_v1_chr6_+_108166015_108166034-0.431.4e-02Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_116526277 2.09 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1
chr6_-_46954922 2.03 ENST00000265417.7
ADGRF5
adhesion G protein-coupled receptor F5
chr3_-_64687613 1.64 ENST00000295903.8
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr1_+_185734362 1.63 ENST00000271588.9
HMCN1
hemicentin 1
chr1_+_31576485 1.50 ENST00000457433.6
ENST00000271064.12
TINAGL1
tubulointerstitial nephritis antigen like 1
chr3_-_64687992 1.46 ENST00000498707.5
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr2_+_191276885 1.43 ENST00000392316.5
MYO1B
myosin IB
chr2_-_89143133 1.41 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr11_-_5254741 1.40 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
HBG2
ENSG00000284931.1
hemoglobin subunit gamma 2
novel protein
chr3_-_64687982 1.28 ENST00000459780.1
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr5_-_33891941 1.26 ENST00000352040.7
ENST00000504830.6
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
chr7_+_143132069 1.20 ENST00000291009.4
PIP
prolactin induced protein
chr4_+_70197924 1.17 ENST00000514097.5
ODAM
odontogenic, ameloblast associated
chr1_-_94927079 1.12 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chr5_-_33892013 1.11 ENST00000515401.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
chr17_-_48590231 1.11 ENST00000476342.1
ENST00000460160.5
ENST00000498678.6
ENST00000472863.5
HOXB3
homeobox B3
chrX_-_66040072 1.11 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chr5_-_91383310 1.09 ENST00000265138.4
ARRDC3
arrestin domain containing 3
chr11_+_31812307 1.09 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAUPAR
ENSG00000285283.1
PAX6 upstream antisense RNA
novel protein
chr12_-_91178520 1.08 ENST00000425043.5
ENST00000420120.6
ENST00000441303.6
ENST00000456569.2
DCN
decorin
chr8_-_121641424 1.08 ENST00000303924.5
HAS2
hyaluronan synthase 2
chrX_-_66040057 1.06 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chrX_-_66040107 1.02 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr3_-_58210961 1.02 ENST00000486455.5
ENST00000394549.7
DNASE1L3
deoxyribonuclease 1 like 3
chr5_+_32711313 1.01 ENST00000265074.13
NPR3
natriuretic peptide receptor 3
chr11_-_5249836 1.00 ENST00000632727.1
ENST00000330597.5
HBG1
hemoglobin subunit gamma 1
chr12_-_70637405 0.95 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
PTPRB
protein tyrosine phosphatase receptor type B
chr12_-_52493250 0.94 ENST00000330722.7
KRT6A
keratin 6A
chr5_+_32711723 0.94 ENST00000415167.2
NPR3
natriuretic peptide receptor 3
chr13_+_110305806 0.92 ENST00000400163.7
COL4A2
collagen type IV alpha 2 chain
chr10_+_122560639 0.86 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr12_+_7062583 0.86 ENST00000542978.1
C1S
complement C1s
chr12_-_52949849 0.85 ENST00000619952.2
ENST00000546826.5
KRT8
keratin 8
chr5_-_150137403 0.85 ENST00000517957.1
PDGFRB
platelet derived growth factor receptor beta
chrX_-_66033664 0.84 ENST00000427538.5
VSIG4
V-set and immunoglobulin domain containing 4
chr11_-_13495984 0.84 ENST00000282091.6
PTH
parathyroid hormone
chr6_+_31948956 0.83 ENST00000483004.1
CFB
complement factor B
chr6_+_148342759 0.83 ENST00000367467.8
SASH1
SAM and SH3 domain containing 1
chr18_+_44680093 0.82 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr9_-_92482499 0.79 ENST00000375544.7
ASPN
asporin
chr11_-_13496018 0.79 ENST00000529816.1
PTH
parathyroid hormone
chr3_+_12351470 0.78 ENST00000287820.10
PPARG
peroxisome proliferator activated receptor gamma
chr6_-_41747390 0.78 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
PGC
progastricsin
chr11_+_102112445 0.77 ENST00000524575.5
YAP1
Yes1 associated transcriptional regulator
chr11_-_111923722 0.77 ENST00000527950.5
CRYAB
crystallin alpha B
chr9_-_92482350 0.76 ENST00000375543.2
ASPN
asporin
chr9_-_92482461 0.75 ENST00000651738.1
ASPN
asporin
chr2_+_90038848 0.74 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr3_-_58211212 0.73 ENST00000461914.7
DNASE1L3
deoxyribonuclease 1 like 3
chr19_-_46717076 0.73 ENST00000601806.5
ENST00000593363.1
ENST00000291281.9
ENST00000598633.1
ENST00000595515.5
ENST00000433867.5
PRKD2
protein kinase D2
chr12_+_56521951 0.72 ENST00000552247.6
RBMS2
RNA binding motif single stranded interacting protein 2
chr10_+_11742361 0.72 ENST00000379215.9
ENST00000420401.5
ECHDC3
enoyl-CoA hydratase domain containing 3
chr3_-_112638097 0.72 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr17_-_68955332 0.71 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ABCA8
ATP binding cassette subfamily A member 8
chr10_+_122560751 0.71 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr16_+_3018390 0.71 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr12_+_56521990 0.71 ENST00000550726.5
ENST00000542360.1
RBMS2
RNA binding motif single stranded interacting protein 2
chr5_-_42811884 0.69 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
SELENOP
selenoprotein P
chr4_-_184805752 0.68 ENST00000513317.5
ACSL1
acyl-CoA synthetase long chain family member 1
chrX_+_47585212 0.68 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr2_-_88860913 0.67 ENST00000390239.2
IGKJ4
immunoglobulin kappa joining 4
chr1_+_212565334 0.65 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr1_+_170664121 0.64 ENST00000239461.11
PRRX1
paired related homeobox 1
chr3_+_12351493 0.64 ENST00000683699.1
PPARG
peroxisome proliferator activated receptor gamma
chr20_-_31722854 0.63 ENST00000307677.5
BCL2L1
BCL2 like 1
chr7_+_116672187 0.61 ENST00000318493.11
ENST00000397752.8
MET
MET proto-oncogene, receptor tyrosine kinase
chr12_-_55842950 0.60 ENST00000548629.5
MMP19
matrix metallopeptidase 19
chr9_+_1050330 0.60 ENST00000382255.7
ENST00000382251.7
ENST00000412350.6
ENST00000358146.7
DMRT2
doublesex and mab-3 related transcription factor 2
chr20_-_31722533 0.59 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2L1
BCL2 like 1
chr11_-_128587551 0.58 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr2_+_205682491 0.56 ENST00000360409.7
ENST00000450507.5
ENST00000357785.10
ENST00000417189.5
NRP2
neuropilin 2
chr2_+_88897230 0.56 ENST00000390244.2
IGKV5-2
immunoglobulin kappa variable 5-2
chrX_+_116170742 0.56 ENST00000371906.5
ENST00000681852.1
AGTR2
angiotensin II receptor type 2
chr20_+_44531817 0.56 ENST00000372889.5
ENST00000372887.5
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr20_-_31722949 0.55 ENST00000376055.9
BCL2L1
BCL2 like 1
chr3_-_169146527 0.55 ENST00000475754.5
ENST00000484519.5
MECOM
MDS1 and EVI1 complex locus
chr1_+_170663917 0.53 ENST00000497230.2
PRRX1
paired related homeobox 1
chr3_+_101827982 0.53 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr8_+_103372388 0.52 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr14_+_69398683 0.49 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
SLC39A9
solute carrier family 39 member 9
chr6_+_142302621 0.49 ENST00000541199.5
ENST00000435011.6
ADGRG6
adhesion G protein-coupled receptor G6
chr2_-_157444044 0.49 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr12_+_85874287 0.48 ENST00000551529.5
ENST00000256010.7
NTS
neurotensin
chr18_+_44680875 0.48 ENST00000649279.2
ENST00000677699.1
SETBP1
SET binding protein 1
chr3_-_50322733 0.47 ENST00000428028.1
ENST00000357750.9
HYAL2
hyaluronidase 2
chr1_-_99766620 0.47 ENST00000646001.2
FRRS1
ferric chelate reductase 1
chr3_+_128052390 0.47 ENST00000481210.5
ENST00000243253.8
SEC61A1
SEC61 translocon subunit alpha 1
chr3_-_169146595 0.47 ENST00000468789.5
MECOM
MDS1 and EVI1 complex locus
chr10_+_122560679 0.47 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr15_-_51243011 0.46 ENST00000405913.7
ENST00000559878.5
CYP19A1
cytochrome P450 family 19 subfamily A member 1
chr14_+_61697622 0.45 ENST00000539097.2
HIF1A
hypoxia inducible factor 1 subunit alpha
chr2_-_189580773 0.45 ENST00000261024.7
SLC40A1
solute carrier family 40 member 1
chr3_-_50322759 0.44 ENST00000442581.1
ENST00000447092.5
HYAL2
hyaluronidase 2
chr14_-_91836440 0.43 ENST00000340892.9
ENST00000360594.9
TC2N
tandem C2 domains, nuclear
chr6_-_138499487 0.43 ENST00000343505.9
NHSL1
NHS like 1
chr8_+_24384455 0.43 ENST00000522298.1
ADAMDEC1
ADAM like decysin 1
chr8_+_24384275 0.43 ENST00000256412.8
ADAMDEC1
ADAM like decysin 1
chr11_-_70717994 0.43 ENST00000659264.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr8_-_118111806 0.43 ENST00000378204.7
EXT1
exostosin glycosyltransferase 1
chr11_-_111910830 0.42 ENST00000526167.5
ENST00000651650.1
CRYAB
crystallin alpha B
chr4_-_47981535 0.41 ENST00000402813.9
CNGA1
cyclic nucleotide gated channel subunit alpha 1
chr7_+_107168961 0.41 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HBP1
HMG-box transcription factor 1
chr3_+_136957948 0.41 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr17_-_43546323 0.41 ENST00000545954.5
ENST00000319349.10
ETV4
ETS variant transcription factor 4
chr11_-_63671909 0.40 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr6_-_138545685 0.40 ENST00000342260.9
NHSL1
NHS like 1
chr12_-_91153149 0.40 ENST00000550758.1
DCN
decorin
chr12_-_31326142 0.40 ENST00000337682.9
SINHCAF
SIN3-HDAC complex associated factor
chr12_-_55842927 0.40 ENST00000322569.9
ENST00000409200.7
MMP19
matrix metallopeptidase 19
chr12_-_89352487 0.40 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr7_+_135148041 0.40 ENST00000275767.3
TMEM140
transmembrane protein 140
chr1_+_62597510 0.39 ENST00000371129.4
ANGPTL3
angiopoietin like 3
chr14_+_36661852 0.39 ENST00000361487.7
PAX9
paired box 9
chr9_-_72953047 0.39 ENST00000297785.8
ENST00000376939.5
ALDH1A1
aldehyde dehydrogenase 1 family member A1
chr3_+_69739425 0.39 ENST00000352241.9
ENST00000642352.1
MITF
melanocyte inducing transcription factor
chr1_-_115768702 0.39 ENST00000261448.6
CASQ2
calsequestrin 2
chr17_+_2056073 0.39 ENST00000576444.1
ENST00000322941.3
HIC1
HIC ZBTB transcriptional repressor 1
chrX_+_47218670 0.39 ENST00000357227.9
ENST00000519758.5
ENST00000520893.5
ENST00000622098.4
ENST00000517426.5
CDK16
cyclin dependent kinase 16
chr6_+_158649997 0.38 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
SYTL3
synaptotagmin like 3
chr6_+_143126183 0.38 ENST00000458219.1
AIG1
androgen induced 1
chr12_+_63844758 0.38 ENST00000631006.2
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr12_+_10213417 0.38 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABARAPL1
GABA type A receptor associated protein like 1
chr9_-_92404559 0.37 ENST00000262551.8
ENST00000375561.10
OGN
osteoglycin
chr4_+_77605807 0.36 ENST00000682537.1
CXCL13
C-X-C motif chemokine ligand 13
chr11_-_111910790 0.36 ENST00000533280.6
CRYAB
crystallin alpha B
chr12_+_53990585 0.36 ENST00000504315.1
HOXC6
homeobox C6
chr6_+_12290353 0.36 ENST00000379375.6
EDN1
endothelin 1
chr1_-_243851066 0.36 ENST00000263826.12
AKT3
AKT serine/threonine kinase 3
chr7_-_106285898 0.36 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chr10_+_17752185 0.36 ENST00000377495.2
TMEM236
transmembrane protein 236
chr3_+_52779916 0.36 ENST00000537050.5
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chrX_+_47218232 0.35 ENST00000457458.6
ENST00000522883.1
CDK16
cyclin dependent kinase 16
chr21_-_34888683 0.35 ENST00000344691.8
ENST00000358356.9
RUNX1
RUNX family transcription factor 1
chr2_+_74458400 0.35 ENST00000393972.7
ENST00000233615.7
ENST00000409737.5
ENST00000428943.1
WBP1
WW domain binding protein 1
chr12_-_31326111 0.34 ENST00000539409.5
SINHCAF
SIN3-HDAC complex associated factor
chr12_-_31326171 0.34 ENST00000542983.1
SINHCAF
SIN3-HDAC complex associated factor
chr4_-_110198650 0.34 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr12_-_7936177 0.34 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr1_-_243850216 0.34 ENST00000673466.1
AKT3
AKT serine/threonine kinase 3
chr4_-_69639642 0.34 ENST00000604629.6
ENST00000604021.1
UGT2A2
UDP glucuronosyltransferase family 2 member A2
chr7_-_42152396 0.34 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI3
GLI family zinc finger 3
chr14_-_91836526 0.33 ENST00000556018.5
TC2N
tandem C2 domains, nuclear
chr9_-_92536645 0.33 ENST00000395534.2
ECM2
extracellular matrix protein 2
chr7_-_13986498 0.33 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETV1
ETS variant transcription factor 1
chr12_+_10213624 0.32 ENST00000545290.1
GABARAPL1
GABA type A receptor associated protein like 1
chr2_-_55010348 0.31 ENST00000394609.6
RTN4
reticulon 4
chr20_+_43945677 0.31 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr4_-_40630588 0.31 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr17_+_75979211 0.30 ENST00000397640.6
ENST00000588202.5
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 subunit of CST complex
chr5_-_83673544 0.30 ENST00000503117.1
ENST00000510978.5
HAPLN1
hyaluronan and proteoglycan link protein 1
chr5_+_172834225 0.30 ENST00000393784.8
ERGIC1
endoplasmic reticulum-golgi intermediate compartment 1
chr2_-_175181663 0.30 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP5MC3
ATP synthase membrane subunit c locus 3
chr7_-_16465728 0.30 ENST00000307068.5
SOSTDC1
sclerostin domain containing 1
chr7_+_114414997 0.29 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
FOXP2
forkhead box P2
chr12_-_50249883 0.29 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr3_-_119677346 0.29 ENST00000484810.5
ENST00000497116.1
ENST00000261070.7
COX17
cytochrome c oxidase copper chaperone COX17
chr19_+_35449584 0.29 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr8_-_18084925 0.29 ENST00000637792.1
ENST00000637991.1
ENST00000636537.1
ENST00000636455.1
ENST00000314146.10
ENST00000381733.9
ASAH1
N-acylsphingosine amidohydrolase 1
chr4_-_40629842 0.29 ENST00000295971.12
RBM47
RNA binding motif protein 47
chr3_+_69866217 0.29 ENST00000314589.10
MITF
melanocyte inducing transcription factor
chr11_-_104898670 0.29 ENST00000422698.6
CASP12
caspase 12 (gene/pseudogene)
chr16_-_69754913 0.29 ENST00000268802.10
NOB1
NIN1 (RPN12) binding protein 1 homolog
chr19_+_18001117 0.28 ENST00000379656.7
ARRDC2
arrestin domain containing 2
chr17_-_69060906 0.28 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ABCA9
ATP binding cassette subfamily A member 9
chr2_-_189582012 0.28 ENST00000427419.5
ENST00000455320.5
SLC40A1
solute carrier family 40 member 1
chr3_-_185821092 0.27 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr19_+_11435332 0.27 ENST00000591946.5
PRKCSH
protein kinase C substrate 80K-H
chr1_+_201739864 0.27 ENST00000367295.5
NAV1
neuron navigator 1
chr4_-_110198579 0.27 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr12_-_57826295 0.27 ENST00000549039.5
CTDSP2
CTD small phosphatase 2
chr3_+_122325237 0.26 ENST00000264474.4
ENST00000479204.1
CSTA
cystatin A
chr6_+_106098933 0.26 ENST00000369089.3
PRDM1
PR/SET domain 1
chr3_+_138621225 0.26 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr1_-_85578345 0.26 ENST00000426972.8
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_23949642 0.26 ENST00000537393.5
ENST00000451604.7
ENST00000381381.6
SOX5
SRY-box transcription factor 5
chrX_-_49184789 0.26 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr12_-_29444236 0.26 ENST00000537054.1
OVCH1
ovochymase 1
chr3_+_138621207 0.26 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr3_-_114178698 0.26 ENST00000467632.5
DRD3
dopamine receptor D3
chr14_-_34874887 0.26 ENST00000382422.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr1_-_154183199 0.25 ENST00000323144.12
ENST00000330188.13
ENST00000328159.9
ENST00000611659.4
TPM3
tropomyosin 3
chr9_-_92404690 0.25 ENST00000447356.1
OGN
osteoglycin
chr7_-_42152444 0.25 ENST00000479210.1
GLI3
GLI family zinc finger 3
chr2_+_200308943 0.25 ENST00000619961.4
SPATS2L
spermatogenesis associated serine rich 2 like
chr9_-_21994345 0.25 ENST00000579755.2
ENST00000530628.2
CDKN2A
cyclin dependent kinase inhibitor 2A
chr11_+_35176696 0.25 ENST00000528455.5
CD44
CD44 molecule (Indian blood group)
chr17_+_29568591 0.25 ENST00000581411.6
ENST00000301057.8
TP53I13
tumor protein p53 inducible protein 13
chr11_+_35176639 0.24 ENST00000527889.6
CD44
CD44 molecule (Indian blood group)
chr7_-_113919000 0.24 ENST00000284601.4
PPP1R3A
protein phosphatase 1 regulatory subunit 3A
chr14_+_61187544 0.24 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
PRKCH
protein kinase C eta
chr12_+_119593758 0.23 ENST00000426426.3
TMEM233
transmembrane protein 233
chr2_+_28395511 0.23 ENST00000436647.1
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr15_+_67067780 0.23 ENST00000679624.1
SMAD3
SMAD family member 3
chr11_+_35176611 0.23 ENST00000279452.10
CD44
CD44 molecule (Indian blood group)
chr14_+_51489112 0.22 ENST00000356218.8
FRMD6
FERM domain containing 6
chr17_+_12666154 0.22 ENST00000343344.8
MYOCD
myocardin
chr5_-_16936231 0.22 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
MYO10
myosin X
chrM_+_10055 0.22 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3
chr11_+_35176575 0.22 ENST00000526000.6
CD44
CD44 molecule (Indian blood group)
chr7_+_116672357 0.22 ENST00000456159.1
MET
MET proto-oncogene, receptor tyrosine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 2.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 2.0 GO:0070295 renal water absorption(GO:0070295)
0.3 1.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 2.3 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 0.8 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.2 4.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.7 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2 0.9 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.2 1.8 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.2 4.4 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.2 0.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) negative regulation of icosanoid secretion(GO:0032304)
0.2 1.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 0.4 GO:0030185 nitric oxide transport(GO:0030185)
0.2 1.4 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 2.1 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0060366 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.1 2.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.1 GO:0021546 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.4 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.8 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 2.0 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 1.0 GO:0001554 luteolysis(GO:0001554)
0.1 1.8 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 0.3 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.5 GO:0001922 B-1 B cell homeostasis(GO:0001922) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.8 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 1.2 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.1 1.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.5 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.1 0.3 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.1 0.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 2.1 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:0089700 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700)
0.1 0.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.3 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.1 0.6 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.7 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.1 0.2 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 1.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.6 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.2 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.6 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.8 GO:0072307 contact inhibition(GO:0060242) metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 1.0 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 1.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.1 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.2 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.5 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.0 GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 1.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:1900148 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0043116 arginine catabolic process(GO:0006527) negative regulation of vascular permeability(GO:0043116)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.5 GO:0006958 complement activation, classical pathway(GO:0006958)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.2 0.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 0.4 GO:0016590 ACF complex(GO:0016590)
0.1 1.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 2.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0033018 junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.8 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:1990696 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 12.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035375 zymogen binding(GO:0035375)
0.5 2.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 2.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.7 GO:0097689 iron channel activity(GO:0097689)
0.2 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.8 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.2 0.9 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.4 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.6 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 1.2 GO:0019864 IgG binding(GO:0019864)
0.1 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 0.7 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 7.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 5.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.4 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.8 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 1.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.0 GO:0061598 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 1.2 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 9.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 2.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction