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Illumina Body Map 2 (GSE30611)

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Results for NR6A1

Z-value: 1.03

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
NR6A1
ENSG00000148200.17 nuclear receptor subfamily 6 group A member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg38_v1_chr9_-_124771238_124771297-0.281.3e-01Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106715166 4.99 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr14_-_106762576 4.75 ENST00000624687.1
IGHV1-69D
immunoglobulin heavy variable 1-69D
chr22_+_22720615 4.58 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr14_-_106185387 4.06 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr19_-_7732160 3.65 ENST00000676742.1
ENST00000678118.1
ENST00000328853.10
CLEC4G
C-type lectin domain family 4 member G
chr14_-_105626066 3.52 ENST00000641978.1
ENST00000390543.3
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr22_+_22887780 3.38 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
IGLL5
immunoglobulin lambda like polypeptide 5
chr14_-_105771405 3.27 ENST00000641136.1
ENST00000390551.6
IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106277039 3.21 ENST00000390610.2
IGHV1-24
immunoglobulin heavy variable 1-24
chr5_-_139389905 3.21 ENST00000302125.9
MZB1
marginal zone B and B1 cell specific protein
chr19_-_10335773 2.85 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr15_-_21718245 2.82 ENST00000630556.1
ENSG00000281179.1
novel gene identicle to IGHV1OR15-1
chr1_-_153544997 2.74 ENST00000368715.5
S100A4
S100 calcium binding protein A4
chr14_-_106737547 2.73 ENST00000632209.1
IGHV1-69-2
immunoglobulin heavy variable 1-69-2
chr5_+_157180816 2.58 ENST00000422843.8
ITK
IL2 inducible T cell kinase
chr14_-_106005574 2.52 ENST00000390595.3
IGHV1-3
immunoglobulin heavy variable 1-3
chr14_-_106507476 2.42 ENST00000390621.3
IGHV1-45
immunoglobulin heavy variable 1-45
chr19_+_41877267 2.41 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule
chr11_-_18248632 1.97 ENST00000524555.3
ENST00000528349.5
ENST00000526900.1
ENST00000529528.5
ENST00000414546.6
SAA2-SAA4
SAA2
SAA2-SAA4 readthrough
serum amyloid A2
chr12_+_9827472 1.97 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
KLRF1
killer cell lectin like receptor F1
chr7_-_150341615 1.96 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
RARRES2
retinoic acid receptor responder 2
chr17_+_47733228 1.86 ENST00000177694.2
TBX21
T-box transcription factor 21
chr11_-_18248662 1.84 ENST00000256733.9
SAA2
serum amyloid A2
chr1_-_160647037 1.78 ENST00000302035.11
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_-_203229660 1.76 ENST00000255427.7
ENST00000367229.6
CHIT1
chitinase 1
chr1_-_183569186 1.71 ENST00000420553.5
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chrX_+_100666854 1.70 ENST00000640282.1
SRPX2
sushi repeat containing protein X-linked 2
chr7_-_88306880 1.70 ENST00000414498.1
ENST00000301959.9
ENST00000380079.9
STEAP4
STEAP4 metalloreductase
chr12_+_53990585 1.69 ENST00000504315.1
HOXC6
homeobox C6
chr10_+_87659839 1.65 ENST00000456849.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr21_-_10649835 1.62 ENST00000622028.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr17_+_50634845 1.60 ENST00000427699.5
ENST00000285238.13
ABCC3
ATP binding cassette subfamily C member 3
chr16_+_31355165 1.58 ENST00000562918.5
ENST00000268296.9
ITGAX
integrin subunit alpha X
chr14_-_99272184 1.53 ENST00000357195.8
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr9_-_134917872 1.52 ENST00000616356.4
ENST00000371806.4
FCN1
ficolin 1
chr1_-_160646958 1.48 ENST00000538290.2
SLAMF1
signaling lymphocytic activation molecule family member 1
chr6_+_32038382 1.47 ENST00000478281.5
ENST00000471671.4
ENST00000435122.3
ENST00000644719.2
CYP21A2
cytochrome P450 family 21 subfamily A member 2
chr17_-_48545077 1.42 ENST00000330070.6
HOXB2
homeobox B2
chr1_-_206921867 1.41 ENST00000628511.2
ENST00000367091.8
FCMR
Fc fragment of IgM receptor
chr16_+_31355215 1.41 ENST00000562522.2
ITGAX
integrin subunit alpha X
chr12_-_7109176 1.40 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
C1RL
complement C1r subcomponent like
chr8_+_143558329 1.39 ENST00000262580.9
ENST00000525721.1
ENST00000534018.5
GSDMD
gasdermin D
chr7_+_142626642 1.38 ENST00000390394.3
TRBV20-1
T cell receptor beta variable 20-1
chr11_-_88337722 1.35 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
CTSC
cathepsin C
chr6_+_31946086 1.34 ENST00000425368.7
CFB
complement factor B
chr12_+_54016879 1.33 ENST00000303406.4
HOXC4
homeobox C4
chr6_+_106086316 1.32 ENST00000369091.6
ENST00000369096.9
PRDM1
PR/SET domain 1
chr10_-_14572123 1.29 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
FAM107B
family with sequence similarity 107 member B
chr1_+_78045956 1.28 ENST00000370759.4
GIPC2
GIPC PDZ domain containing family member 2
chrX_-_119693150 1.27 ENST00000394610.7
SEPTIN6
septin 6
chr7_-_27152561 1.25 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
ENSG00000273433.1
HOXA3
ENSG00000272801.1
novel transcript
homeobox A3
novel transcript
chr3_+_114294020 1.25 ENST00000383671.8
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr1_+_110873135 1.22 ENST00000271324.6
CD53
CD53 molecule
chr7_+_100602344 1.22 ENST00000223061.6
PCOLCE
procollagen C-endopeptidase enhancer
chr2_+_90190193 1.20 ENST00000390278.3
IGKV1D-42
immunoglobulin kappa variable 1D-42 (non-functional)
chr5_-_41213505 1.19 ENST00000337836.10
ENST00000433294.1
C6
complement C6
chr10_-_75235917 1.19 ENST00000469299.1
ENST00000372538.8
COMTD1
catechol-O-methyltransferase domain containing 1
chr2_+_68774782 1.17 ENST00000409030.7
ENST00000409220.5
ARHGAP25
Rho GTPase activating protein 25
chr20_+_45174894 1.17 ENST00000243924.4
PI3
peptidase inhibitor 3
chr11_+_112086853 1.14 ENST00000528182.5
ENST00000528048.5
ENST00000375549.8
ENST00000528021.6
ENST00000526592.5
ENST00000525291.5
SDHD
succinate dehydrogenase complex subunit D
chr17_-_48604959 1.13 ENST00000225648.4
ENST00000484302.3
HOXB6
homeobox B6
chr11_-_64744102 1.12 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RASGRP2
RAS guanyl releasing protein 2
chr19_-_14518383 1.11 ENST00000254322.3
ENST00000595139.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr6_+_37005630 1.10 ENST00000274963.13
FGD2
FYVE, RhoGEF and PH domain containing 2
chr14_+_61485391 1.09 ENST00000640011.1
PRKCH
protein kinase C eta
chr15_+_40765620 1.08 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_+_81699665 1.08 ENST00000359929.7
ADGRL2
adhesion G protein-coupled receptor L2
chr19_+_3762705 1.08 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr8_-_23225061 1.08 ENST00000613472.1
ENST00000221132.8
TNFRSF10A
TNF receptor superfamily member 10a
chr7_+_142740206 1.06 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chrX_+_136648138 1.05 ENST00000370629.7
CD40LG
CD40 ligand
chr1_+_159800503 1.05 ENST00000536257.5
ENST00000321935.10
FCRL6
Fc receptor like 6
chr3_-_146528750 1.03 ENST00000483300.5
PLSCR1
phospholipid scramblase 1
chr17_-_19042485 1.03 ENST00000395635.5
GRAP
GRB2 related adaptor protein
chr11_-_64744811 1.02 ENST00000377497.7
ENST00000377487.5
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2
chr1_-_147773341 1.02 ENST00000430508.1
ENST00000621517.1
GJA5
gap junction protein alpha 5
chr1_-_27366917 1.01 ENST00000357582.3
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr12_-_47820562 1.00 ENST00000433685.5
ENST00000447463.5
ENST00000427332.6
HDAC7
histone deacetylase 7
chr16_+_81739027 0.98 ENST00000566191.5
ENST00000565272.5
ENST00000563954.5
ENST00000565054.5
ENSG00000261218.5
PLCG2
novel transcript
phospholipase C gamma 2
chr7_+_143288215 0.98 ENST00000619992.4
ENST00000310447.10
CASP2
caspase 2
chr19_-_14517425 0.97 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr19_-_6720641 0.97 ENST00000245907.11
C3
complement C3
chr1_-_160647287 0.96 ENST00000235739.6
SLAMF1
signaling lymphocytic activation molecule family member 1
chr21_+_33205279 0.96 ENST00000683941.1
IFNAR2
interferon alpha and beta receptor subunit 2
chr8_-_118951876 0.95 ENST00000297350.9
TNFRSF11B
TNF receptor superfamily member 11b
chr17_+_7435416 0.94 ENST00000323206.2
ENST00000396568.1
TMEM102
transmembrane protein 102
chr19_+_49487510 0.94 ENST00000679106.1
ENST00000621674.4
ENST00000391857.9
ENST00000678510.1
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr7_+_142424942 0.92 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr9_-_14314519 0.91 ENST00000397581.6
NFIB
nuclear factor I B
chr11_+_65639860 0.90 ENST00000527525.5
SIPA1
signal-induced proliferation-associated 1
chr2_+_68774921 0.90 ENST00000497079.5
ARHGAP25
Rho GTPase activating protein 25
chr16_-_11629210 0.89 ENST00000576036.5
LITAF
lipopolysaccharide induced TNF factor
chr5_+_96875978 0.89 ENST00000510373.5
ERAP2
endoplasmic reticulum aminopeptidase 2
chr19_+_41576206 0.89 ENST00000187608.13
CEACAM21
CEA cell adhesion molecule 21
chr19_+_49453211 0.88 ENST00000540132.5
ENST00000293350.9
ENST00000455361.6
ALDH16A1
aldehyde dehydrogenase 16 family member A1
chr12_+_12891554 0.88 ENST00000014914.6
GPRC5A
G protein-coupled receptor class C group 5 member A
chr14_+_22202561 0.88 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr14_-_95714114 0.87 ENST00000402399.6
ENST00000555202.1
TCL1A
TCL1 family AKT coactivator A
chr2_+_236569817 0.87 ENST00000272928.4
ACKR3
atypical chemokine receptor 3
chr9_-_127916978 0.87 ENST00000361444.3
ENST00000335791.10
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr9_-_14314132 0.85 ENST00000380953.6
NFIB
nuclear factor I B
chr12_+_9827517 0.85 ENST00000537723.5
KLRF1
killer cell lectin like receptor F1
chr2_-_189179754 0.84 ENST00000374866.9
ENST00000618828.1
COL5A2
collagen type V alpha 2 chain
chr3_+_72996842 0.83 ENST00000495566.1
PPP4R2
protein phosphatase 4 regulatory subunit 2
chr2_-_68952880 0.83 ENST00000481498.1
ENST00000328895.9
GKN2
gastrokine 2
chr21_+_42219123 0.83 ENST00000398449.8
ABCG1
ATP binding cassette subfamily G member 1
chr5_-_181242195 0.82 ENST00000502905.5
RACK1
receptor for activated C kinase 1
chr19_-_14529193 0.82 ENST00000596853.6
ENST00000676515.1
ENST00000678338.1
ENST00000595992.6
ENST00000677848.1
ENST00000677762.1
ENST00000678009.1
ENST00000596075.2
ENST00000601533.6
ENST00000396969.8
ENST00000598692.2
ENST00000678098.1
DNAJB1
DnaJ heat shock protein family (Hsp40) member B1
chr11_-_6440980 0.82 ENST00000265983.8
ENST00000615166.1
HPX
hemopexin
chr16_-_3256587 0.81 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV
MEFV innate immuity regulator, pyrin
chr1_+_159587817 0.81 ENST00000255040.3
APCS
amyloid P component, serum
chr19_+_679894 0.81 ENST00000589185.2
FSTL3
follistatin like 3
chr9_-_14313843 0.78 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
NFIB
nuclear factor I B
chr7_+_80624071 0.78 ENST00000438020.5
CD36
CD36 molecule
chr17_+_76079182 0.78 ENST00000334586.10
ZACN
zinc activated ion channel
chr10_-_14572087 0.78 ENST00000482277.5
ENST00000378462.5
FAM107B
family with sequence similarity 107 member B
chr16_+_726936 0.74 ENST00000549114.5
ENST00000341413.8
ENST00000562187.1
ENST00000564537.5
ENST00000389703.8
HAGHL
hydroxyacylglutathione hydrolase like
chr16_+_30201057 0.74 ENST00000569485.5
SULT1A3
sulfotransferase family 1A member 3
chrX_-_119693370 0.74 ENST00000360156.11
ENST00000354228.8
ENST00000489216.5
ENST00000354416.7
ENST00000343984.5
SEPTIN6
septin 6
chr2_-_85398734 0.74 ENST00000453973.5
CAPG
capping actin protein, gelsolin like
chr7_+_72879349 0.73 ENST00000395270.5
POM121
POM121 transmembrane nucleoporin
chr3_-_129561051 0.72 ENST00000506979.1
PLXND1
plexin D1
chr5_-_181242236 0.72 ENST00000507756.5
RACK1
receptor for activated C kinase 1
chr1_-_16206491 0.72 ENST00000441785.1
ENST00000449495.1
ARHGEF19
Rho guanine nucleotide exchange factor 19
chr14_-_95714146 0.72 ENST00000554012.5
TCL1A
TCL1 family AKT coactivator A
chr16_+_727739 0.71 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase like
chr12_-_53200443 0.71 ENST00000550743.6
ITGB7
integrin subunit beta 7
chr10_+_112375196 0.70 ENST00000393081.6
ACSL5
acyl-CoA synthetase long chain family member 5
chr1_+_28887072 0.69 ENST00000647103.1
ENST00000642937.2
ENST00000646189.1
ENST00000644342.1
ENST00000373800.7
ENST00000649717.1
EPB41
erythrocyte membrane protein band 4.1
chr7_+_18086934 0.69 ENST00000417496.6
HDAC9
histone deacetylase 9
chr6_-_31730198 0.68 ENST00000375787.6
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr11_-_64246907 0.68 ENST00000309318.8
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr8_-_38269157 0.68 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
PLPP5
phospholipid phosphatase 5
chr10_-_14571969 0.68 ENST00000488576.5
ENST00000472095.5
FAM107B
family with sequence similarity 107 member B
chr5_-_181241605 0.67 ENST00000504128.5
RACK1
receptor for activated C kinase 1
chr2_+_233760265 0.67 ENST00000305208.10
ENST00000360418.4
UGT1A1
UDP glucuronosyltransferase family 1 member A1
chr3_-_132684685 0.66 ENST00000512094.5
ENST00000632629.1
NPHP3
NPHP3-ACAD11
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr3_+_152269103 0.65 ENST00000459747.1
MBNL1
muscleblind like splicing regulator 1
chr11_-_64996963 0.65 ENST00000301887.9
ENST00000534177.1
BATF2
basic leucine zipper ATF-like transcription factor 2
chr5_+_52787899 0.64 ENST00000274311.3
ENST00000282588.7
PELO
ITGA1
pelota mRNA surveillance and ribosome rescue factor
integrin subunit alpha 1
chr10_+_58512864 0.63 ENST00000373886.8
BICC1
BicC family RNA binding protein 1
chr19_+_41193230 0.63 ENST00000600561.1
CYP2S1
cytochrome P450 family 2 subfamily S member 1
chr19_+_41193198 0.62 ENST00000597754.1
ENST00000310054.9
CYP2S1
cytochrome P450 family 2 subfamily S member 1
chr15_+_100879822 0.61 ENST00000329841.10
ENST00000557963.1
ENST00000346623.6
ALDH1A3
aldehyde dehydrogenase 1 family member A3
chr9_-_14314067 0.61 ENST00000397575.7
NFIB
nuclear factor I B
chr10_-_70132801 0.61 ENST00000307864.3
ENST00000613322.4
AIFM2
apoptosis inducing factor mitochondria associated 2
chr3_+_171843337 0.61 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
TMEM212
transmembrane protein 212
chr12_+_57229694 0.61 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
SHMT2
serine hydroxymethyltransferase 2
chr5_-_14011743 0.61 ENST00000681290.1
DNAH5
dynein axonemal heavy chain 5
chr6_+_144659814 0.60 ENST00000367525.3
UTRN
utrophin
chr17_+_79034185 0.60 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr14_+_58634055 0.59 ENST00000556859.5
ENST00000421793.5
DACT1
dishevelled binding antagonist of beta catenin 1
chr22_-_30471986 0.59 ENST00000401751.5
ENST00000402286.5
ENST00000403066.5
ENST00000215812.9
SEC14L3
SEC14 like lipid binding 3
chr14_+_19875142 0.59 ENST00000641885.1
OR4K2
olfactory receptor family 4 subfamily K member 2
chr1_-_153608136 0.58 ENST00000368703.6
S100A16
S100 calcium binding protein A16
chr7_-_6484057 0.58 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDELR2
DAGLB
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chrX_+_48786562 0.57 ENST00000651144.1
ENST00000376665.4
GATA1
GATA binding protein 1
chr2_-_60553618 0.57 ENST00000643716.1
ENST00000359629.10
ENST00000642384.2
ENST00000335712.11
BCL11A
BAF chromatin remodeling complex subunit BCL11A
chr19_-_58353482 0.57 ENST00000263100.8
A1BG
alpha-1-B glycoprotein
chr2_-_162074050 0.56 ENST00000676768.1
DPP4
dipeptidyl peptidase 4
chr16_+_22507174 0.56 ENST00000541154.5
NPIPB5
nuclear pore complex interacting protein family member B5
chr14_-_95714088 0.56 ENST00000556450.5
TCL1A
TCL1 family AKT coactivator A
chr9_-_111599813 0.55 ENST00000538962.7
PTGR1
prostaglandin reductase 1
chr3_+_152268920 0.55 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
MBNL1
muscleblind like splicing regulator 1
chr7_+_143288364 0.55 ENST00000392925.6
CASP2
caspase 2
chr17_+_75093287 0.55 ENST00000538213.6
ENST00000584118.1
SLC16A5
solute carrier family 16 member 5
chr11_-_5254741 0.54 ENST00000444587.1
ENST00000336906.6
ENST00000642908.1
ENST00000647543.1
HBG2
ENSG00000284931.1
hemoglobin subunit gamma 2
novel protein
chr5_+_34656446 0.54 ENST00000428746.6
RAI14
retinoic acid induced 14
chr7_+_120989030 0.54 ENST00000428526.5
CPED1
cadherin like and PC-esterase domain containing 1
chr11_-_101583985 0.54 ENST00000344327.8
TRPC6
transient receptor potential cation channel subfamily C member 6
chr3_-_124841410 0.54 ENST00000496703.1
ITGB5
integrin subunit beta 5
chr17_-_40937445 0.54 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr19_+_49496424 0.53 ENST00000596873.1
ENST00000594493.1
ENST00000270625.7
ENST00000599561.1
RPS11
ribosomal protein S11
chr10_-_14572313 0.53 ENST00000479731.5
ENST00000468492.5
FAM107B
family with sequence similarity 107 member B
chr22_-_21629991 0.53 ENST00000292778.11
ENST00000398873.4
YDJC
YdjC chitooligosaccharide deacetylase homolog
chr12_+_12891853 0.52 ENST00000534831.1
GPRC5A
G protein-coupled receptor class C group 5 member A
chr6_-_33580229 0.52 ENST00000374467.4
ENST00000442998.6
ENST00000360661.9
BAK1
BCL2 antagonist/killer 1
chr7_-_151080833 0.52 ENST00000353841.6
ENST00000482571.2
FASTK
Fas activated serine/threonine kinase
chr5_-_177409535 0.52 ENST00000253496.4
F12
coagulation factor XII
chr2_+_237692144 0.52 ENST00000289175.10
ENST00000244815.9
LRRFIP1
LRR binding FLII interacting protein 1
chr5_-_75052546 0.51 ENST00000652361.2
GCNT4
glucosaminyl (N-acetyl) transferase 4
chr19_+_3762665 0.51 ENST00000330133.5
MRPL54
mitochondrial ribosomal protein L54
chr11_-_112086727 0.50 ENST00000504148.3
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B
chr2_-_42361149 0.50 ENST00000468711.5
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr19_-_344786 0.49 ENST00000264819.7
MIER2
MIER family member 2
chr5_-_113294895 0.49 ENST00000514701.5
ENST00000302475.8
MCC
MCC regulator of WNT signaling pathway
chrX_+_48786578 0.48 ENST00000376670.9
GATA1
GATA binding protein 1
chr12_-_54297884 0.48 ENST00000553198.1
NFE2
nuclear factor, erythroid 2
chr1_+_43978913 0.48 ENST00000498543.1
B4GALT2
beta-1,4-galactosyltransferase 2
chr9_-_38069220 0.48 ENST00000377707.4
SHB
SH2 domain containing adaptor protein B
chr22_+_37024137 0.47 ENST00000628507.1
MPST
mercaptopyruvate sulfurtransferase
chr20_+_3071618 0.47 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr16_-_21864103 0.47 ENST00000541674.5
NPIPB4
nuclear pore complex interacting protein family member B4
chr5_+_34656288 0.46 ENST00000265109.8
RAI14
retinoic acid induced 14
chr6_-_25874212 0.46 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr22_-_42640601 0.46 ENST00000505920.1
ATP5MGL
ATP synthase membrane subunit g like
chr8_-_16186270 0.46 ENST00000445506.6
MSR1
macrophage scavenger receptor 1
chr17_+_78214186 0.46 ENST00000301633.8
ENST00000350051.8
ENST00000374948.6
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr19_+_10086787 0.45 ENST00000590378.5
ENST00000397881.7
SHFL
shiftless antiviral inhibitor of ribosomal frameshifting
chr14_-_75981986 0.45 ENST00000238682.8
TGFB3
transforming growth factor beta 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.7 2.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.6 3.2 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.6 1.7 GO:0000103 sulfate assimilation(GO:0000103)
0.5 1.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 1.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.4 1.3 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.4 1.2 GO:0009720 detection of hormone stimulus(GO:0009720)
0.4 1.5 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 30.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 1.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.4 1.1 GO:0030221 basophil differentiation(GO:0030221)
0.3 1.0 GO:0035922 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.3 2.0 GO:0061760 antifungal innate immune response(GO:0061760)
0.3 1.0 GO:0002316 follicular B cell differentiation(GO:0002316)
0.3 3.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.0 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.3 1.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 0.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.3 1.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 2.2 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.2 1.7 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.5 GO:0002125 maternal aggressive behavior(GO:0002125)
0.2 0.9 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 2.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.6 GO:1904863 regulation of beta-catenin-TCF complex assembly(GO:1904863) negative regulation of beta-catenin-TCF complex assembly(GO:1904864)
0.2 0.4 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 1.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 0.5 GO:0002339 B cell selection(GO:0002339)
0.2 0.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 2.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 0.7 GO:0018879 biphenyl metabolic process(GO:0018879)
0.2 0.5 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 0.3 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 1.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.9 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.2 0.6 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 3.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 3.5 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.8 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 1.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0021503 neural fold bending(GO:0021503)
0.1 2.1 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 0.8 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 1.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.3 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 9.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.1 GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production(GO:0071650)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0097327 response to antineoplastic agent(GO:0097327)
0.1 0.3 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.1 0.4 GO:0035962 response to interleukin-13(GO:0035962)
0.1 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.9 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.6 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.2 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.4 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 1.1 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.5 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.3 GO:0019050 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
0.1 1.2 GO:0007620 copulation(GO:0007620)
0.1 3.8 GO:0006953 acute-phase response(GO:0006953)
0.0 1.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.4 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.7 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.4 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 1.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.7 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 2.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.6 GO:0021670 lateral ventricle development(GO:0021670)
0.0 1.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 1.0 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.2 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 2.1 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 2.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.5 GO:0015671 oxygen transport(GO:0015671)
0.0 2.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 2.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.4 GO:0006968 cellular defense response(GO:0006968)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 2.7 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 2.1 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.8 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.1 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.7 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 29.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 2.4 GO:0019814 immunoglobulin complex(GO:0019814)
0.2 1.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.2 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.2 1.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 0.7 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 1.7 GO:0032010 phagolysosome(GO:0032010)
0.2 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 1.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 3.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.9 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 2.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.0 GO:0008305 integrin complex(GO:0008305)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0070552 BRISC complex(GO:0070552)
0.0 0.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.0 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 4.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.6 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 1.7 GO:0035580 specific granule lumen(GO:0035580)
0.0 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0045178 basal part of cell(GO:0045178)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.3 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.4 29.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 1.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 1.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.1 GO:0045569 TRAIL binding(GO:0045569)
0.2 1.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 2.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 1.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.0 GO:0086020 gap junction hemi-channel activity(GO:0055077) gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 1.0 GO:0004905 type I interferon receptor activity(GO:0004905)
0.2 0.6 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 2.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.2 0.5 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 0.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.6 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 3.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 2.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.5 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 1.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 1.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 1.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 3.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.8 GO:0031404 chloride ion binding(GO:0031404)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.6 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.9 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 13.8 GO:0003823 antigen binding(GO:0003823)
0.1 0.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.6 GO:0001848 complement binding(GO:0001848)
0.1 2.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 2.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 2.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 2.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 1.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.8 GO:0051400 BH domain binding(GO:0051400)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 3.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.8 GO:0048185 activin binding(GO:0048185)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 1.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 5.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 4.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 1.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 7.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 3.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 9.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions