ISMARA results: ONECUT1

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Illumina Body Map 2 (GSE30611)

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Results for ONECUT1

Z-value: 2.39

Motif logo

Transcription factors associated with ONECUT1

Gene Symbol	Gene ID	Gene Info
ONECUT1 Ensembl NCBI GeneCards UniProt	ENSG00000169856.9	one cut homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ONECUT1	hg38_v1_chr15_-_52790324_52790352	0.76	3.9e-07	Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_159714581 Show fit	19.52	ENST00000255030.9 ENST00000437342.1 ENST00000368112.5 ENST00000368111.5 ENST00000368110.1	CRP Ensembl NCBI GeneCards UniProt Show fit	C-reactive protein
chr1_+_56854764 Show fit	18.04	ENST00000361249.4	C8A Ensembl NCBI GeneCards UniProt Show fit	complement C8 alpha chain
chr17_-_28370283 Show fit	17.84	ENST00000226218.9	VTN Ensembl NCBI GeneCards UniProt Show fit	vitronectin
chr9_-_114078293 Show fit	16.88	ENST00000265132.8	AMBP Ensembl NCBI GeneCards UniProt Show fit	alpha-1-microglobulin/bikunin precursor
chr1_+_159587817 Show fit	16.82	ENST00000255040.3	APCS Ensembl NCBI GeneCards UniProt Show fit	amyloid P component, serum
chr13_-_46105009 Show fit	16.40	ENST00000439329.5 ENST00000674625.1 ENST00000181383.10	CPB2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B2
chr12_+_111034136 Show fit	14.90	ENST00000261726.11	CUX2 Ensembl NCBI GeneCards UniProt Show fit	cut like homeobox 2
chr3_-_171026709 Show fit	13.57	ENST00000314251.8	SLC2A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 2
chr3_+_186666003 Show fit	13.24	ENST00000232003.5	HRG Ensembl NCBI GeneCards UniProt Show fit	histidine rich glycoprotein
chr3_+_52777580 Show fit	13.14	ENST00000273283.7	ITIH1 Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain 1
chr19_+_44946043 Show fit	10.24	ENST00000252490.7 ENST00000591597.5	APOC2 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C2
chr1_+_207089233 Show fit	9.82	ENST00000243611.9 ENST00000367076.7	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr17_+_42900791 Show fit	9.69	ENST00000592383.5 ENST00000253801.7 ENST00000585489.1	G6PC1 Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphatase catalytic subunit 1
chr17_-_66229380 Show fit	9.66	ENST00000205948.11	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chr16_+_27203480 Show fit	9.27	ENST00000286096.9	KDM8 Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 8
chrX_+_71215156 Show fit	9.02	ENST00000374029.2 ENST00000675209.1 ENST00000647424.1 ENST00000675368.1 ENST00000675609.1 ENST00000646835.1 ENST00000447581.2	GJB1 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein beta 1
chr10_+_113553039 Show fit	8.85	ENST00000351270.4	HABP2 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan binding protein 2
chr19_+_44946009 Show fit	8.50	ENST00000592257.5	APOC2 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C2
chr2_+_234050679 Show fit	8.49	ENST00000373368.5 ENST00000168148.8	SPP2 Ensembl NCBI GeneCards UniProt Show fit	secreted phosphoprotein 2
chr12_-_52903648 Show fit	8.32	ENST00000546900.1	KRT8 Ensembl NCBI GeneCards UniProt Show fit	keratin 8
chr1_+_207089195 Show fit	8.28	ENST00000452902.6	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr5_-_177409535 Show fit	8.25	ENST00000253496.4	F12 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XII
chr1_+_207089283 Show fit	7.48	ENST00000391923.1	C4BPB Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr12_+_56752449 Show fit	7.45	ENST00000554643.5 ENST00000556650.5 ENST00000554150.5 ENST00000554155.1	HSD17B6 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 17-beta dehydrogenase 6
chr19_-_58353482 Show fit	7.33	ENST00000263100.8	A1BG Ensembl NCBI GeneCards UniProt Show fit	alpha-1-B glycoprotein
chr18_-_27990256 Show fit	6.29	ENST00000675173.1	CDH2 Ensembl NCBI GeneCards UniProt Show fit	cadherin 2
chr1_+_196888014 Show fit	5.99	ENST00000367416.6 ENST00000608469.6 ENST00000251424.8 ENST00000367418.2	CFHR4 Ensembl NCBI GeneCards UniProt Show fit	complement factor H related 4
chr12_+_56230043 Show fit	5.91	ENST00000424625.5 ENST00000419753.5 ENST00000454355.7 ENST00000417965.5 ENST00000436633.5	SLC39A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 5
chr20_-_22585451 Show fit	5.72	ENST00000377115.4	FOXA2 Ensembl NCBI GeneCards UniProt Show fit	forkhead box A2
chr2_+_234050732 Show fit	5.61	ENST00000425558.1	SPP2 Ensembl NCBI GeneCards UniProt Show fit	secreted phosphoprotein 2
chr2_+_233691607 Show fit	5.51	ENST00000373424.5 ENST00000441351.1	UGT1A6 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A6
chr3_+_119782094 Show fit	5.51	ENST00000393716.8	NR1I2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 1 group I member 2
chr10_+_47322450 Show fit	5.13	ENST00000581492.3	GDF2 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 2
chr12_+_56230652 Show fit	5.04	ENST00000266980.8 ENST00000437277.1	SLC39A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 5
chr1_-_151831768 Show fit	5.00	ENST00000318247.7	RORC Ensembl NCBI GeneCards UniProt Show fit	RAR related orphan receptor C
chr10_-_92243246 Show fit	4.66	ENST00000412050.8 ENST00000614585.4	CPEB3 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic polyadenylation element binding protein 3
chr5_+_42756811 Show fit	4.58	ENST00000388827.4 ENST00000361970.10	CCDC152 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 152
chr1_-_154194648 Show fit	4.54	ENST00000515609.1	TPM3 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 3
chr7_-_122144231 Show fit	4.51	ENST00000679511.1 ENST00000417368.7 ENST00000473553.5	AASS Ensembl NCBI GeneCards UniProt Show fit	aminoadipate-semialdehyde synthase
chrX_+_123184153 Show fit	4.39	ENST00000616590.4	GRIA3 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 3
chr11_-_19201976 Show fit	4.34	ENST00000647990.1 ENST00000649235.1 ENST00000265968.9 ENST00000649842.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr1_-_151831837 Show fit	4.31	ENST00000652040.1	RORC Ensembl NCBI GeneCards UniProt Show fit	RAR related orphan receptor C
chr13_-_113364141 Show fit	4.21	ENST00000620217.4 ENST00000375430.8	GRTP1 Ensembl NCBI GeneCards UniProt Show fit	growth hormone regulated TBC protein 1
chr4_-_74099187 Show fit	4.18	ENST00000508487.3	CXCL2 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 2
chr18_+_49560684 Show fit	3.91	ENST00000577628.5	LIPG Ensembl NCBI GeneCards UniProt Show fit	lipase G, endothelial type
chr12_+_21526287 Show fit	3.76	ENST00000256969.7	SPX Ensembl NCBI GeneCards UniProt Show fit	spexin hormone
chr3_-_165196689 Show fit	3.63	ENST00000241274.3	SLITRK3 Ensembl NCBI GeneCards UniProt Show fit	SLIT and NTRK like family member 3
chr13_-_113364085 Show fit	3.63	ENST00000375431.9	GRTP1 Ensembl NCBI GeneCards UniProt Show fit	growth hormone regulated TBC protein 1
chr12_-_9115907 Show fit	3.47	ENST00000318602.12	A2M Ensembl NCBI GeneCards UniProt Show fit	alpha-2-macroglobulin
chr10_+_68109433 Show fit	3.42	ENST00000613327.4 ENST00000358913.10 ENST00000373675.3	MYPN Ensembl NCBI GeneCards UniProt Show fit	myopalladin
chr4_+_158806069 Show fit	3.39	ENST00000512986.5	FNIP2 Ensembl NCBI GeneCards UniProt Show fit	folliculin interacting protein 2
chrX_+_123184260 Show fit	3.33	ENST00000620443.2 ENST00000622768.5 ENST00000611689.4	GRIA3 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 3
chr13_+_29428709 Show fit	3.33	ENST00000542829.1	MTUS2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated scaffold protein 2
chr1_-_197067234 Show fit	3.32	ENST00000367412.2	F13B Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XIII B chain
chr22_-_37109703 Show fit	3.22	ENST00000406856.7 ENST00000676104.1	TMPRSS6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane serine protease 6
chr11_-_19202004 Show fit	3.18	ENST00000648719.1	CSRP3 Ensembl NCBI GeneCards UniProt Show fit	cysteine and glycine rich protein 3
chr17_-_17582417 Show fit	3.14	ENST00000395783.5	PEMT Ensembl NCBI GeneCards UniProt Show fit	phosphatidylethanolamine N-methyltransferase
chr11_+_57597563 Show fit	3.13	ENST00000619430.2 ENST00000457869.1 ENST00000340687.10 ENST00000278407.9 ENST00000378323.8 ENST00000378324.6 ENST00000403558.1	SERPING1 Ensembl NCBI GeneCards UniProt Show fit	serpin family G member 1
chr1_-_8015633 Show fit	3.08	ENST00000467067.1	ERRFI1 Ensembl NCBI GeneCards UniProt Show fit	ERBB receptor feedback inhibitor 1
chr14_+_73591873 Show fit	3.06	ENST00000326303.5	ACOT4 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA thioesterase 4
chr2_-_85561513 Show fit	3.05	ENST00000430215.7	GGCX Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl carboxylase
chr13_+_29428603 Show fit	3.04	ENST00000380808.6	MTUS2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated scaffold protein 2
chr3_+_142596385 Show fit	3.00	ENST00000457734.7 ENST00000483373.5 ENST00000475296.5 ENST00000495744.5 ENST00000476044.5 ENST00000461644.5 ENST00000464320.5	PLS1 Ensembl NCBI GeneCards UniProt Show fit	plastin 1
chr20_+_44355692 Show fit	2.95	ENST00000316673.8 ENST00000609795.5 ENST00000457232.5 ENST00000609262.5	HNF4A Ensembl NCBI GeneCards UniProt Show fit	hepatocyte nuclear factor 4 alpha
chr22_-_37109409 Show fit	2.82	ENST00000406725.6	TMPRSS6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane serine protease 6
chr9_-_98708856 Show fit	2.64	ENST00000259455.4	GABBR2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type B receptor subunit 2
chr7_+_55019010 Show fit	2.51	ENST00000344576.7 ENST00000275493.7 ENST00000455089.5	EGFR Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor
chr1_-_209802149 Show fit	2.50	ENST00000456314.1	IRF6 Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 6
chr14_+_73616844 Show fit	2.41	ENST00000381139.1	ACOT6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA thioesterase 6
chr10_-_34815257 Show fit	2.41	ENST00000374789.8 ENST00000374788.8 ENST00000346874.9 ENST00000374794.8 ENST00000350537.9 ENST00000374790.8 ENST00000374776.6 ENST00000374773.6 ENST00000545260.5 ENST00000545693.5 ENST00000340077.9	PARD3 Ensembl NCBI GeneCards UniProt Show fit	par-3 family cell polarity regulator
chr7_+_99828010 Show fit	2.35	ENST00000631161.2 ENST00000354829.7 ENST00000342499.8 ENST00000417625.5 ENST00000415413.5 ENST00000444905.5 ENST00000222382.5 ENST00000312017.9	CYP3A43 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 3 subfamily A member 43
chrX_+_10156960 Show fit	2.34	ENST00000380833.9	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr4_+_158210444 Show fit	2.33	ENST00000512481.5	TMEM144 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 144
chrM_-_14669 Show fit	2.33	ENST00000361681.2	MT-ND6 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr19_-_4535221 Show fit	2.23	ENST00000381848.7 ENST00000586133.1	PLIN5 Ensembl NCBI GeneCards UniProt Show fit	perilipin 5
chr19_-_47512766 Show fit	2.23	ENST00000598615.5 ENST00000597118.1	NAPA Ensembl NCBI GeneCards UniProt Show fit	NSF attachment protein alpha
chr4_-_17511981 Show fit	2.22	ENST00000505710.1	QDPR Ensembl NCBI GeneCards UniProt Show fit	quinoid dihydropteridine reductase
chrX_-_132489954 Show fit	2.20	ENST00000370844.5	MBNL3 Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 3
chr2_-_199851114 Show fit	2.20	ENST00000420128.5 ENST00000416668.5 ENST00000622774.2	FTCDNL1 Ensembl NCBI GeneCards UniProt Show fit	formiminotransferase cyclodeaminase N-terminal like
chr4_+_109912877 Show fit	2.19	ENST00000265171.10 ENST00000509793.5 ENST00000652245.1	EGF Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor
chr2_+_222671651 Show fit	2.18	ENST00000446656.4	MOGAT1 Ensembl NCBI GeneCards UniProt Show fit	monoacylglycerol O-acyltransferase 1
chr5_+_139795795 Show fit	2.13	ENST00000274710.4	PSD2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 2
chr1_+_113390495 Show fit	2.09	ENST00000307546.14	MAGI3 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr9_+_128068172 Show fit	2.05	ENST00000373068.6 ENST00000373069.10	SLC25A25 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 25
chr12_-_118052597 Show fit	2.03	ENST00000535496.5	WSB2 Ensembl NCBI GeneCards UniProt Show fit	WD repeat and SOCS box containing 2
chr7_+_55019032 Show fit	2.02	ENST00000342916.7 ENST00000454757.6 ENST00000420316.6	EGFR Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor
chr19_+_2785481 Show fit	1.99	ENST00000307741.11 ENST00000585338.1	THOP1 Ensembl NCBI GeneCards UniProt Show fit	thimet oligopeptidase 1
chr2_-_196592671 Show fit	1.98	ENST00000260983.8 ENST00000644030.1	HECW2 Ensembl NCBI GeneCards UniProt Show fit	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr10_-_5185104 Show fit	1.95	ENST00000648824.1 ENST00000650030.1	AKR1C8P Ensembl NCBI GeneCards UniProt Show fit	aldo-keto reductase family 1 member C8, pseudogene
chr18_+_49561013 Show fit	1.93	ENST00000583083.1	LIPG Ensembl NCBI GeneCards UniProt Show fit	lipase G, endothelial type
chr3_+_159839847 Show fit	1.92	ENST00000445224.6	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chrM_+_8366 Show fit	1.92	ENST00000361851.1	MT-ATP8 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded ATP synthase membrane subunit 8
chr12_-_10826358 Show fit	1.85	ENST00000240619.2	TAS2R10 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 10
chr4_-_174522315 Show fit	1.83	ENST00000514584.5	HPGD Ensembl NCBI GeneCards UniProt Show fit	15-hydroxyprostaglandin dehydrogenase
chr16_+_7332839 Show fit	1.82	ENST00000355637.9	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr1_+_26169891 Show fit	1.75	ENST00000374266.7 ENST00000270812.6	ZNF593 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 593
chr8_-_18683932 Show fit	1.75	ENST00000615573.4	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr2_-_86623807 Show fit	1.74	ENST00000237455.5	RNF103 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 103
chrM_+_14740 Show fit	1.72	ENST00000361789.2	MT-CYB Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded cytochrome b
chr11_-_35418966 Show fit	1.72	ENST00000531628.2	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr21_-_25735026 Show fit	1.68	ENST00000400099.5 ENST00000457143.6	ATP5PF Ensembl NCBI GeneCards UniProt Show fit	ATP synthase peripheral stalk subunit F6
chr11_+_34977778 Show fit	1.62	ENST00000526309.1	PDHX Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase complex component X
chr21_-_25734887 Show fit	1.62	ENST00000400094.5 ENST00000284971.8	ATP5PF Ensembl NCBI GeneCards UniProt Show fit	ATP synthase peripheral stalk subunit F6
chr11_+_112025968 Show fit	1.59	ENST00000680411.1	DLAT Ensembl NCBI GeneCards UniProt Show fit	dihydrolipoamide S-acetyltransferase
chr11_-_30016945 Show fit	1.59	ENST00000328224.7	KCNA4 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 4
chr1_-_177970213 Show fit	1.56	ENST00000464631.6	SEC16B Ensembl NCBI GeneCards UniProt Show fit	SEC16 homolog B, endoplasmic reticulum export factor
chr1_+_232805384 Show fit	1.55	ENST00000418460.4	MAP10 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 10
chr19_-_6501766 Show fit	1.54	ENST00000596291.1	TUBB4A Ensembl NCBI GeneCards UniProt Show fit	tubulin beta 4A class IVa
chrX_-_33211312 Show fit	1.51	ENST00000420596.5 ENST00000448370.5	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr15_-_85794902 Show fit	1.40	ENST00000337975.6	KLHL25 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 25
chr1_-_115841116 Show fit	1.39	ENST00000320238.3	NHLH2 Ensembl NCBI GeneCards UniProt Show fit	nescient helix-loop-helix 2
chr5_-_61162352 Show fit	1.38	ENST00000339020.8 ENST00000507416.1	SMIM15 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 15
chr4_+_25234003 Show fit	1.35	ENST00000264864.8	PI4K2B Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol 4-kinase type 2 beta
chr12_-_21334858 Show fit	1.32	ENST00000445053.1 ENST00000458504.5 ENST00000422327.5 ENST00000683939.1	SLCO1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 1A2
chr5_-_152405277 Show fit	1.31	ENST00000255262.4	NMUR2 Ensembl NCBI GeneCards UniProt Show fit	neuromedin U receptor 2
chr9_+_125747345 Show fit	1.30	ENST00000342287.9 ENST00000373489.10 ENST00000373487.8	PBX3 Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox 3
chr20_+_21705651 Show fit	1.30	ENST00000398485.6 ENST00000613128.5	PAX1 Ensembl NCBI GeneCards UniProt Show fit	paired box 1
chr1_+_156619406 Show fit	1.29	ENST00000255039.6 ENST00000456112.1	HAPLN2 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 2
chr7_-_6484057 Show fit	1.28	ENST00000490996.1 ENST00000258739.9 ENST00000436575.5	KDELR2 Ensembl NCBI GeneCards UniProt Show fit DAGLB Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 2 diacylglycerol lipase beta
chr8_+_119873710 Show fit	1.28	ENST00000523492.5 ENST00000286234.6	DEPTOR Ensembl NCBI GeneCards UniProt Show fit	DEP domain containing MTOR interacting protein
chr8_-_27611200 Show fit	1.28	ENST00000520796.5 ENST00000520491.5	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chrM_+_8489 Show fit	1.26	ENST00000361899.2	MT-ATP6 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded ATP synthase membrane subunit 6
chr12_-_55966018 Show fit	1.25	ENST00000548803.5 ENST00000449260.6 ENST00000550447.5 ENST00000547137.5 ENST00000546543.5 ENST00000548747.6 ENST00000550464.5	PMEL Ensembl NCBI GeneCards UniProt Show fit	premelanosome protein
chr12_-_10909562 Show fit	1.23	ENST00000390677.2	TAS2R13 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 13
chr4_+_168497113 Show fit	1.22	ENST00000511948.1	PALLD Ensembl NCBI GeneCards UniProt Show fit	palladin, cytoskeletal associated protein
chr4_+_158210479 Show fit	1.22	ENST00000504569.5 ENST00000509278.5 ENST00000514558.5 ENST00000503200.5 ENST00000296529.11	TMEM144 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 144
chr3_+_120908072 Show fit	1.20	ENST00000273666.10 ENST00000471454.6 ENST00000472879.5 ENST00000497029.5 ENST00000492541.5	STXBP5L Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 5 like
chr10_+_96304392 Show fit	1.20	ENST00000630152.1	DNTT Ensembl NCBI GeneCards UniProt Show fit	DNA nucleotidylexotransferase
chr10_+_96304425 Show fit	1.20	ENST00000371174.5	DNTT Ensembl NCBI GeneCards UniProt Show fit	DNA nucleotidylexotransferase
chr9_+_137241277 Show fit	1.19	ENST00000340384.5	TUBB4B Ensembl NCBI GeneCards UniProt Show fit	tubulin beta 4B class IVb
chr12_-_95942592 Show fit	1.18	ENST00000546947.5 ENST00000344280.8 ENST00000546386.1	CCDC38 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 38
chr3_+_32238667 Show fit	1.17	ENST00000458535.6 ENST00000307526.4	CMTM8 Ensembl NCBI GeneCards UniProt Show fit	CKLF like MARVEL transmembrane domain containing 8
chr1_-_202710428 Show fit	1.16	ENST00000367268.5	SYT2 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 2
chr7_+_90403506 Show fit	1.16	ENST00000427904.1	CLDN12 Ensembl NCBI GeneCards UniProt Show fit	claudin 12
chr3_+_58306236 Show fit	1.12	ENST00000295959.10 ENST00000445193.7 ENST00000466547.1 ENST00000475412.5 ENST00000474660.5 ENST00000477305.5 ENST00000481972.5	RPP14 Ensembl NCBI GeneCards UniProt Show fit HTD2 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease P/MRP subunit p14 hydroxyacyl-thioester dehydratase type 2
chr1_+_247948858 Show fit	1.09	ENST00000623922.1	OR2L8 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily L member 8
chr12_+_19236880 Show fit	1.08	ENST00000536974.5	PLEKHA5 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing A5
chr2_+_44941695 Show fit	1.08	ENST00000260653.5	SIX3 Ensembl NCBI GeneCards UniProt Show fit	SIX homeobox 3
chr18_-_27185284 Show fit	1.08	ENST00000580774.2 ENST00000618847.5	CHST9 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 9
chr21_-_7789509 Show fit	1.06	ENST00000646133.1	SMIM34B Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 34B
chr11_+_85647958 Show fit	1.05	ENST00000304511.7 ENST00000528105.5	TMEM126A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 126A
chr7_-_72447061 Show fit	1.04	ENST00000395276.6 ENST00000431984.5	CALN1 Ensembl NCBI GeneCards UniProt Show fit	calneuron 1
chr8_-_27611325 Show fit	1.04	ENST00000523500.5	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr9_-_73038711 Show fit	1.01	ENST00000446946.1	ALDH1A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A1
chr11_+_61228377 Show fit	1.00	ENST00000537932.5	PGA4 Ensembl NCBI GeneCards UniProt Show fit	pepsinogen A4
chrX_-_132128020 Show fit	0.98	ENST00000298542.9	FRMD7 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 7
chr6_+_10694916 Show fit	0.98	ENST00000379568.4	PAK1IP1 Ensembl NCBI GeneCards UniProt Show fit	PAK1 interacting protein 1
chr13_+_110615622 Show fit	0.98	ENST00000309957.3 ENST00000680505.1	NAXD Ensembl NCBI GeneCards UniProt Show fit	NAD(P)HX dehydratase
chr19_-_13599860 Show fit	0.96	ENST00000664864.1	CACNA1A Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel subunit alpha1 A
chr12_+_70366277 Show fit	0.95	ENST00000258111.5	KCNMB4 Ensembl NCBI GeneCards UniProt Show fit	potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr12_+_101475319 Show fit	0.93	ENST00000551346.2	SPIC Ensembl NCBI GeneCards UniProt Show fit	Spi-C transcription factor
chrX_-_111410919 Show fit	0.93	ENST00000496551.2	DCX Ensembl NCBI GeneCards UniProt Show fit	doublecortin
chr1_+_248095184 Show fit	0.91	ENST00000358120.3 ENST00000641893.1	OR2L13 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily L member 13
chr2_-_58241259 Show fit	0.90	ENST00000481670.2 ENST00000403676.5 ENST00000427708.6 ENST00000403295.7 ENST00000233741.9 ENST00000446381.5 ENST00000417361.1 ENST00000402135.7 ENST00000449070.5	FANCL Ensembl NCBI GeneCards UniProt Show fit	FA complementation group L
chr17_-_17591658 Show fit	0.90	ENST00000435340.6 ENST00000255389.10 ENST00000395781.6	PEMT Ensembl NCBI GeneCards UniProt Show fit	phosphatidylethanolamine N-methyltransferase
chrX_-_33211462 Show fit	0.89	ENST00000682071.1 ENST00000684237.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr7_+_141764097 Show fit	0.88	ENST00000247879.2	TAS2R3 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 3
chr11_-_5986985 Show fit	0.87	ENST00000332249.4	OR52L1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 52 subfamily L member 1
chr3_-_191282383 Show fit	0.85	ENST00000427544.6	UTS2B Ensembl NCBI GeneCards UniProt Show fit	urotensin 2B
chr5_-_20575850 Show fit	0.84	ENST00000507958.5	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18
chr7_-_82005790 Show fit	0.84	ENST00000443883.1	CACNA2D1 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr13_+_110615516 Show fit	0.82	ENST00000680254.1 ENST00000424185.7 ENST00000679389.1	NAXD Ensembl NCBI GeneCards UniProt Show fit	NAD(P)HX dehydratase
chr6_-_138218491 Show fit	0.81	ENST00000527246.3	PBOV1 Ensembl NCBI GeneCards UniProt Show fit	prostate and breast cancer overexpressed 1
chr3_+_101827982 Show fit	0.81	ENST00000461724.5 ENST00000483180.5 ENST00000394054.6	NFKBIZ Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor zeta
chr3_-_112974912 Show fit	0.79	ENST00000440122.6 ENST00000490004.1	CD200R1 Ensembl NCBI GeneCards UniProt Show fit	CD200 receptor 1
chr11_-_72674394 Show fit	0.78	ENST00000418754.6 ENST00000334456.10 ENST00000542969.2	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr6_-_154247422 Show fit	0.77	ENST00000519190.1	IPCEF1 Ensembl NCBI GeneCards UniProt Show fit	interaction protein for cytohesin exchange factors 1
chr5_+_127649018 Show fit	0.76	ENST00000379445.7	CTXN3 Ensembl NCBI GeneCards UniProt Show fit	cortexin 3
chr2_-_144518415 Show fit	0.74	ENST00000409211.5	ZEB2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chr9_+_107306459 Show fit	0.74	ENST00000457811.1	RAD23B Ensembl NCBI GeneCards UniProt Show fit	RAD23 homolog B, nucleotide excision repair protein
chr17_+_41712325 Show fit	0.74	ENST00000329402.4	GAST Ensembl NCBI GeneCards UniProt Show fit	gastrin
chr1_+_77779618 Show fit	0.73	ENST00000370791.7 ENST00000443751.3 ENST00000645756.1 ENST00000643390.1 ENST00000642959.1	MIGA1 Ensembl NCBI GeneCards UniProt Show fit	mitoguardin 1
chr11_-_58423313 Show fit	0.72	ENST00000302581.2	OR5B2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily B member 2
chrX_-_72572794 Show fit	0.72	ENST00000421523.6 ENST00000648036.1 ENST00000373559.8 ENST00000648139.1 ENST00000650636.1 ENST00000648962.1 ENST00000373560.7 ENST00000373568.7 ENST00000373573.9 ENST00000647654.1 ENST00000647859.1 ENST00000415409.6 ENST00000648298.1 ENST00000649752.1 ENST00000373571.6 ENST00000647980.1 ENST00000650126.1 ENST00000373554.6 ENST00000648870.1 ENST00000373556.8 ENST00000647886.1 ENST00000648452.1 ENST00000647594.1 ENST00000373583.6 ENST00000648922.1	HDAC8 Ensembl NCBI GeneCards UniProt Show fit ENSG00000285547.1 Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 8 novel protein
chr10_-_125816596 Show fit	0.70	ENST00000368786.5	UROS Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen III synthase
chr6_+_29111560 Show fit	0.69	ENST00000377169.2	OR2J3 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily J member 3
chr12_-_106084023 Show fit	0.68	ENST00000553094.1 ENST00000549704.1	NUAK1 Ensembl NCBI GeneCards UniProt Show fit	NUAK family kinase 1
chr8_-_11475902 Show fit	0.66	ENST00000648766.1	FAM167A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 167 member A
chr15_-_99249523 Show fit	0.66	ENST00000560235.1 ENST00000394132.7 ENST00000560860.5 ENST00000558078.5 ENST00000560772.5	TTC23 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 23
chr8_+_32646838 Show fit	0.64	ENST00000651333.1 ENST00000652592.1	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr13_-_52011337 Show fit	0.64	ENST00000400366.6 ENST00000400370.8 ENST00000634844.1 ENST00000673772.1 ENST00000418097.7 ENST00000242839.10 ENST00000344297.9 ENST00000448424.7	ATP7B Ensembl NCBI GeneCards UniProt Show fit	ATPase copper transporting beta
chr4_+_75724569 Show fit	0.64	ENST00000514213.7 ENST00000264904.8	USO1 Ensembl NCBI GeneCards UniProt Show fit	USO1 vesicle transport factor
chr10_+_117197489 Show fit	0.62	ENST00000334549.1	KCNK18 Ensembl NCBI GeneCards UniProt Show fit	potassium two pore domain channel subfamily K member 18
chr2_-_172102893 Show fit	0.61	ENST00000234198.9 ENST00000466293.2	DLX2 Ensembl NCBI GeneCards UniProt Show fit	distal-less homeobox 2
chr7_+_103297425 Show fit	0.60	ENST00000428154.5 ENST00000249269.9	PMPCB Ensembl NCBI GeneCards UniProt Show fit	peptidase, mitochondrial processing subunit beta
chr13_+_31199959 Show fit	0.60	ENST00000343307.5	B3GLCT Ensembl NCBI GeneCards UniProt Show fit	beta 3-glucosyltransferase
chr10_+_66926028 Show fit	0.60	ENST00000361320.5	LRRTM3 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 3
chr12_+_19129779 Show fit	0.60	ENST00000539256.5 ENST00000299275.10 ENST00000538714.5	PLEKHA5 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing A5
chr15_+_30903849 Show fit	0.59	ENST00000561594.5 ENST00000658773.1 ENST00000657391.1 ENST00000656435.1	FAN1 Ensembl NCBI GeneCards UniProt Show fit	FANCD2 and FANCI associated nuclease 1
chr9_+_65700287 Show fit	0.59	ENST00000489273.1	CBWD5 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 5
chr15_+_74129620 Show fit	0.59	ENST00000565159.5 ENST00000567206.5	ISLR2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily containing leucine rich repeat 2
chr12_+_15322529 Show fit	0.59	ENST00000348962.7	PTPRO Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type O
chr3_+_181711915 Show fit	0.57	ENST00000325404.3	SOX2 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 2
chr10_-_60572599 Show fit	0.57	ENST00000503366.5	ANK3 Ensembl NCBI GeneCards UniProt Show fit	ankyrin 3
chr3_+_58306505 Show fit	0.56	ENST00000461393.7	HTD2 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacyl-thioester dehydratase type 2
chr10_-_46019498 Show fit	0.55	ENST00000583565.5	NCOA4 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 4
chr12_-_54259531 Show fit	0.55	ENST00000550411.5 ENST00000439541.6	CBX5 Ensembl NCBI GeneCards UniProt Show fit	chromobox 5
chr17_+_75543149 Show fit	0.55	ENST00000580925.1	LLGL2 Ensembl NCBI GeneCards UniProt Show fit	LLGL scribble cell polarity complex component 2
chr15_-_88546585 Show fit	0.53	ENST00000649547.1 ENST00000558413.1 ENST00000564406.5 ENST00000268148.13	ENSG00000173867.10 Ensembl NCBI GeneCards UniProt Show fit DET1 Ensembl NCBI GeneCards UniProt Show fit	novel transcript DET1 partner of COP1 E3 ubiquitin ligase
chr2_-_99254281 Show fit	0.52	ENST00000409238.5 ENST00000423800.5	LYG2 Ensembl NCBI GeneCards UniProt Show fit	lysozyme g2

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	16.8	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
4.7	18.7	GO:0010902	positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
4.1	16.4	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
3.3	13.2	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
2.8	25.6	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
2.7	11.0	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
2.7	13.6	GO:0070837	dehydroascorbic acid transport(GO:0070837)
2.1	8.3	GO:0051919	activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
1.6	6.6	GO:0001869	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.6	4.7	GO:0019878	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
1.6	4.7	GO:1900365	positive regulation of mRNA polyadenylation(GO:1900365)
1.5	5.8	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
1.5	5.8	GO:0010983	positive regulation of high-density lipoprotein particle clearance(GO:0010983)
1.4	5.7	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.3	16.9	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
1.1	9.7	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
1.0	19.5	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
1.0	18.0	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.9	17.8	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.9	7.4	GO:0006710	androgen catabolic process(GO:0006710)
0.8	7.5	GO:0035995	detection of muscle stretch(GO:0035995)
0.7	2.2	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.6	5.5	GO:0046618	drug export(GO:0046618)
0.6	3.0	GO:1902896	terminal web assembly(GO:1902896)
0.6	3.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.6	14.9	GO:0007614	short-term memory(GO:0007614)
0.6	6.3	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.6	5.5	GO:0052696	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5	3.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.5	8.3	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.5	3.8	GO:1904304	negative regulation of renal sodium excretion(GO:0035814) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.5	11.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.4	4.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.4	2.2	GO:0035359	negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4	2.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.4	1.3	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.4	9.3	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.4	1.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.3	2.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.3	3.1	GO:0042536	negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.3	9.3	GO:0036315	cellular response to sterol(GO:0036315)
0.3	2.3	GO:1902847	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3	1.3	GO:0007386	compartment pattern specification(GO:0007386)
0.3	1.3	GO:0061056	sclerotome development(GO:0061056)
0.2	2.2	GO:0035494	SNARE complex disassembly(GO:0035494)
0.2	2.9	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.2	6.0	GO:0097264	self proteolysis(GO:0097264)
0.2	1.8	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2	0.6	GO:0060003	copper ion export(GO:0060003)
0.2	0.8	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2	3.4	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.2	13.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.2	0.7	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2	3.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2	0.7	GO:0071418	cellular response to amine stimulus(GO:0071418)
0.2	5.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.6	GO:1902868	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2	3.2	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2	1.8	GO:2001300	lipoxin metabolic process(GO:2001300)
0.2	0.3	GO:0032289	central nervous system myelin formation(GO:0032289)
0.2	0.5	GO:0035038	female pronucleus assembly(GO:0035038)
0.1	2.4	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1	2.3	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1	0.5	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.1	0.8	GO:0086048	membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1	1.3	GO:0006621	protein retention in ER lumen(GO:0006621)
0.1	7.9	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1	0.8	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1	1.7	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	1.0	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	12.4	GO:0046849	bone remodeling(GO:0046849)
0.1	3.3	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.1	4.0	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	1.6	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.3	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	3.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.1	0.2	GO:0071529	cementum mineralization(GO:0071529)
0.1	1.6	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	1.1	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.1	1.8	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	1.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	2.5	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.1	0.6	GO:1900827	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1	2.4	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.9	GO:1902748	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1	4.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.7	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1	0.6	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.1	0.3	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	2.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	4.9	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	1.7	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.1	0.5	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1	0.6	GO:0001714	endodermal cell fate specification(GO:0001714)
0.1	0.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	7.8	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	1.5	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	2.4	GO:0033198	response to ATP(GO:0033198)
0.0	2.6	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.2	GO:0007056	spindle assembly involved in female meiosis(GO:0007056)
0.0	1.5	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.6	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	1.0	GO:0015671	oxygen transport(GO:0015671)
0.0	0.6	GO:0071435	potassium ion export(GO:0071435)
0.0	1.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	1.3	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	1.0	GO:0005513	detection of calcium ion(GO:0005513)
0.0	2.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.4	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.0	1.9	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	1.5	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	0.3	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	1.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	1.8	GO:0046710	GDP metabolic process(GO:0046710)
0.0	1.8	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	5.4	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.7	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0	1.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	2.6	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	1.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	1.2	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:1990258	box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0	0.3	GO:0038129	ERBB3 signaling pathway(GO:0038129)
0.0	1.9	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	1.3	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.7	GO:0032094	response to food(GO:0032094)
0.0	3.0	GO:0006637	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.5	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.7	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.5	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.1	GO:2000465	regulation of glycogen (starch) synthase activity(GO:2000465)
0.0	0.0	GO:0002380	immunoglobulin secretion involved in immune response(GO:0002380)
0.0	1.4	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0	0.9	GO:0001824	blastocyst development(GO:0001824)
0.0	0.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	4.4	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	1.2	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.5	GO:0021591	ventricular system development(GO:0021591)
0.0	1.3	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.5	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	1.0	GO:0086010	membrane depolarization during action potential(GO:0086010)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	17.8	GO:0071062	rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.3	18.7	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
2.0	18.0	GO:0005579	membrane attack complex(GO:0005579)
1.5	4.5	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
1.1	23.8	GO:0031089	platelet dense granule lumen(GO:0031089)
0.8	3.2	GO:0045259	mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.5	2.6	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5	3.0	GO:1990357	terminal web(GO:1990357)
0.4	2.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3	13.2	GO:0036019	endolysosome(GO:0036019)
0.3	4.0	GO:0033269	internode region of axon(GO:0033269)
0.3	9.0	GO:0005922	connexon complex(GO:0005922)
0.3	4.5	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.3	1.6	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2	1.6	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.2	59.2	GO:0072562	blood microparticle(GO:0072562)
0.2	8.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	6.3	GO:0016342	catenin complex(GO:0016342)
0.2	25.6	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	4.7	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	2.3	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1	2.4	GO:0016013	syntrophin complex(GO:0016013)
0.1	1.2	GO:0042584	chromaffin granule membrane(GO:0042584)
0.1	3.8	GO:0031045	dense core granule(GO:0031045)
0.1	7.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	0.7	GO:0071942	XPC complex(GO:0071942)
0.1	1.1	GO:0030681	multimeric ribonuclease P complex(GO:0030681)
0.1	0.3	GO:0071817	MMXD complex(GO:0071817)
0.1	5.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	1.0	GO:0097486	multivesicular body lumen(GO:0097486)
0.1	7.5	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.5	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	14.1	GO:0005903	brush border(GO:0005903)
0.0	0.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	1.8	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	2.4	GO:0000791	euchromatin(GO:0000791)
0.0	0.5	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	1.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	1.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	2.0	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	7.7	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.8	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.5	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	3.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	2.0	GO:0030673	axolemma(GO:0030673)
0.0	0.5	GO:0044754	autolysosome(GO:0044754)
0.0	0.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	6.4	GO:0030018	Z disc(GO:0030018)
0.0	11.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	2.2	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0072687	meiotic spindle(GO:0072687)
0.0	2.3	GO:0070469	respiratory chain(GO:0070469)
0.0	2.4	GO:0072686	mitotic spindle(GO:0072686)
0.0	2.2	GO:0005811	lipid particle(GO:0005811)
0.0	35.9	GO:0005615	extracellular space(GO:0005615)
0.0	2.0	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	3.7	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.6	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	1.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	0.9	GO:0045171	intercellular bridge(GO:0045171)
0.0	2.0	GO:0032587	ruffle membrane(GO:0032587)
0.0	7.7	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	12.8	GO:0000139	Golgi membrane(GO:0000139)
0.0	2.1	GO:0005923	bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.9	19.5	GO:0033265	choline binding(GO:0033265)
4.7	28.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
2.7	13.6	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
2.4	16.9	GO:0019862	IgA binding(GO:0019862)
2.1	16.8	GO:0001849	complement component C1q binding(GO:0001849)
1.3	4.0	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.9	4.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.8	1.6	GO:0016418	S-acetyltransferase activity(GO:0016418)
0.7	9.3	GO:0008142	oxysterol binding(GO:0008142)
0.6	18.0	GO:0001848	complement binding(GO:0001848)
0.6	18.0	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6	3.4	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.6	2.2	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.6	2.2	GO:0070404	NADH binding(GO:0070404)
0.5	7.4	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.5	7.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.4	13.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.4	2.6	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.4	1.8	GO:0031177	acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.4	3.5	GO:0019959	interleukin-8 binding(GO:0019959) tumor necrosis factor binding(GO:0043120)
0.4	9.0	GO:0005243	gap junction channel activity(GO:0005243)
0.4	1.3	GO:0005046	KDEL sequence binding(GO:0005046)
0.4	7.5	GO:0031433	telethonin binding(GO:0031433)
0.4	16.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.4	5.8	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4	2.2	GO:0035473	lipase binding(GO:0035473)
0.4	9.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4	1.8	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3	10.6	GO:0051787	misfolded protein binding(GO:0051787)
0.3	0.9	GO:0070336	flap-structured DNA binding(GO:0070336)
0.3	0.8	GO:0086057	voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.3	2.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.3	4.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.2	11.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	1.6	GO:0034603	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2	0.6	GO:0043682	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2	5.5	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.2	6.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	1.7	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2	1.7	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.2	4.0	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	0.7	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.2	4.7	GO:0035613	RNA stem-loop binding(GO:0035613)
0.2	1.4	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2	0.5	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1	2.1	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1	0.5	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.1	0.5	GO:0005042	netrin receptor activity(GO:0005042)
0.1	1.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	4.5	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1	5.5	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.3	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	1.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.1	1.0	GO:0005497	androgen binding(GO:0005497) benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	2.5	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	16.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	2.2	GO:0005542	folic acid binding(GO:0005542)
0.1	1.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	3.8	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	2.3	GO:0070330	aromatase activity(GO:0070330)
0.1	2.4	GO:0002162	dystroglycan binding(GO:0002162)
0.1	3.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1	8.5	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	0.8	GO:0030911	TPR domain binding(GO:0030911)
0.1	1.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	9.5	GO:0004866	endopeptidase inhibitor activity(GO:0004866)
0.1	0.3	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	8.3	GO:0097110	scaffold protein binding(GO:0097110)
0.1	2.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	1.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	5.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.1	1.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.3	GO:0047273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1	1.3	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	4.0	GO:1901476	carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0	1.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	1.6	GO:0030955	potassium ion binding(GO:0030955)
0.0	12.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	1.0	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	3.0	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	1.3	GO:0042923	neuropeptide binding(GO:0042923)
0.0	2.3	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	2.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	1.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	9.9	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	1.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	1.8	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	10.1	GO:0005539	glycosaminoglycan binding(GO:0005539)
0.0	1.0	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.3	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	4.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.8	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.7	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	1.5	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	3.1	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	1.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.7	GO:0035198	miRNA binding(GO:0035198)
0.0	0.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.3	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	9.6	GO:0008017	microtubule binding(GO:0008017)
0.0	0.1	GO:0036009	protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	2.3	GO:0015078	hydrogen ion transmembrane transporter activity(GO:0015078)
0.0	0.5	GO:0008301	DNA binding, bending(GO:0008301)
0.0	4.4	GO:0017124	SH3 domain binding(GO:0017124)
0.0	3.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	2.4	GO:0005319	lipid transporter activity(GO:0005319)
0.0	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	4.4	GO:0004984	olfactory receptor activity(GO:0004984)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	0.7	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.5	17.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	27.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	16.5	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	20.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	63.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	7.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	8.3	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	2.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	7.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	4.4	PID ALK1 PATHWAY	ALK1 signaling events
0.1	4.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	5.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	1.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	3.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.3	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.6	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.3	PID MTOR 4PATHWAY	mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	19.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.1	43.6	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.9	22.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.5	14.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.4	11.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	9.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.3	11.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.3	3.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	3.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	5.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	7.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	7.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	3.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	8.7	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	6.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	4.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	14.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	7.3	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	15.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	11.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.7	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.1	3.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	4.1	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	1.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	4.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	1.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	2.3	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.9	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	1.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.6	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	1.0	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	1.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.7	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	7.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.4	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.5	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	4.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	1.8	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	2.1	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	2.0	REACTOME L1CAM INTERACTIONS	Genes involved in L1CAM interactions
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport

Results for ONECUT1

Z-value: 2.39

Motif logo

Transcription factors associated with ONECUT1

Activity-expression correlation:

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: