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Illumina Body Map 2 (GSE30611)

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Results for OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Z-value: 0.84

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Transcription factors associated with OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

Gene Symbol Gene ID Gene Info
OTP
ENSG00000171540.8 orthopedia homeobox
PHOX2B
ENSG00000109132.7 paired like homeobox 2B
LHX1
ENSG00000273706.5 LIM homeobox 1
LMX1A
ENSG00000162761.14 LIM homeobox transcription factor 1 alpha
LHX5
ENSG00000089116.4 LIM homeobox 5
HOXC4
ENSG00000198353.8 homeobox C4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PHOX2Bhg38_v1_chr4_-_41748713_417487310.345.5e-02Click!
LMX1Ahg38_v1_chr1_-_165355746_1653557790.336.6e-02Click!
OTPhg38_v1_chr5_-_77638713_776387130.309.2e-02Click!
LHX1hg38_v1_chr17_+_36942198_36942298-0.222.4e-01Click!
HOXC4hg38_v1_chr12_+_54016879_540169310.212.5e-01Click!
LHX5hg38_v1_chr12_-_113471851_1134718760.163.8e-01Click!

Activity profile of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Sorted Z-values of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_168497044 3.96 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chr4_+_168497066 3.91 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr19_+_49513353 3.46 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chrX_+_154304923 3.39 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
TKTL1
transketolase like 1
chr20_-_31390580 3.11 ENST00000339144.3
ENST00000376321.4
DEFB119
defensin beta 119
chr15_+_22015233 2.68 ENST00000639059.1
ENST00000640156.1
ENSG00000285472.1
ENSG00000284500.3
novel protein
novel transcript
chr6_-_49964160 2.59 ENST00000322066.4
DEFB114
defensin beta 114
chr17_+_12665882 2.29 ENST00000425538.6
MYOCD
myocardin
chr1_-_92486916 2.21 ENST00000294702.6
GFI1
growth factor independent 1 transcriptional repressor
chr20_-_31390483 2.06 ENST00000376315.2
DEFB119
defensin beta 119
chr19_+_49513154 2.02 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
FCGRT
Fc fragment of IgG receptor and transporter
chr15_+_21579912 2.00 ENST00000628444.1
LINC02203
long intergenic non-protein coding RNA 2203
chr6_+_130018565 1.85 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr4_+_118888829 1.83 ENST00000448416.6
ENST00000307142.9
ENST00000429713.7
SYNPO2
synaptopodin 2
chr17_+_12666154 1.79 ENST00000343344.8
MYOCD
myocardin
chr6_+_113857333 1.74 ENST00000612661.2
MARCKS
myristoylated alanine rich protein kinase C substrate
chr3_-_165078480 1.68 ENST00000264382.8
SI
sucrase-isomaltase
chr3_-_191282383 1.63 ENST00000427544.6
UTS2B
urotensin 2B
chr7_+_134843884 1.62 ENST00000445569.6
CALD1
caldesmon 1
chr4_+_118888918 1.60 ENST00000434046.6
SYNPO2
synaptopodin 2
chr2_+_181986015 1.58 ENST00000409702.1
PPP1R1C
protein phosphatase 1 regulatory inhibitor subunit 1C
chr10_-_32935511 1.58 ENST00000423113.5
ITGB1
integrin subunit beta 1
chr9_+_122371036 1.50 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr9_+_122371014 1.49 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr2_-_40453438 1.43 ENST00000455476.5
SLC8A1
solute carrier family 8 member A1
chr14_+_19719015 1.42 ENST00000557414.1
OR4N2
olfactory receptor family 4 subfamily N member 2
chr2_+_181985846 1.30 ENST00000682840.1
ENST00000409137.7
ENST00000280295.7
PPP1R1C
protein phosphatase 1 regulatory inhibitor subunit 1C
chr1_-_113871665 1.28 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
PTPN22
protein tyrosine phosphatase non-receptor type 22
chr5_+_67004618 1.23 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr4_-_67963441 1.22 ENST00000508048.6
TMPRSS11A
transmembrane serine protease 11A
chr7_-_84492718 1.21 ENST00000424555.5
SEMA3A
semaphorin 3A
chr7_+_116222804 1.19 ENST00000393481.6
TES
testin LIM domain protein
chr9_+_122370523 1.17 ENST00000643810.1
ENST00000540753.6
PTGS1
prostaglandin-endoperoxide synthase 1
chr15_+_100877714 1.14 ENST00000561338.5
ALDH1A3
aldehyde dehydrogenase 1 family member A3
chr2_-_89085787 1.12 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr14_+_21997531 1.08 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr13_+_45702411 1.03 ENST00000610924.1
CBY2
chibby family member 2
chr2_-_89027700 1.00 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chrX_+_83861126 0.99 ENST00000621735.4
ENST00000329312.5
CYLC1
cylicin 1
chr13_+_45702306 0.98 ENST00000533564.1
ENST00000310521.6
CBY2
chibby family member 2
chr13_-_99258366 0.97 ENST00000397470.5
ENST00000397473.7
GPR18
G protein-coupled receptor 18
chr2_+_90172802 0.94 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chrX_-_139965510 0.93 ENST00000370540.2
CXorf66
chromosome X open reading frame 66
chr6_-_32190170 0.92 ENST00000375050.6
PBX2
PBX homeobox 2
chr3_-_142029108 0.91 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr4_-_48114523 0.91 ENST00000506073.1
TXK
TXK tyrosine kinase
chr11_+_60327250 0.91 ENST00000684409.1
MS4A6E
membrane spanning 4-domains A6E
chr1_-_157700738 0.90 ENST00000368186.9
ENST00000496769.1
ENST00000368184.8
FCRL3
Fc receptor like 3
chr2_+_90038848 0.88 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr17_+_1771688 0.87 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin family F member 1
chrX_+_108045050 0.85 ENST00000458383.1
ENST00000217957.10
VSIG1
V-set and immunoglobulin domain containing 1
chr17_-_55722857 0.83 ENST00000424486.3
TMEM100
transmembrane protein 100
chr4_+_70226116 0.83 ENST00000317987.6
FDCSP
follicular dendritic cell secreted protein
chr2_-_288759 0.83 ENST00000452023.1
ALKAL2
ALK and LTK ligand 2
chr16_+_28553908 0.80 ENST00000317058.8
SGF29
SAGA complex associated factor 29
chr14_+_30577752 0.80 ENST00000547532.5
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr4_-_106368772 0.79 ENST00000638719.4
GIMD1
GIMAP family P-loop NTPase domain containing 1
chr17_-_48610971 0.77 ENST00000239165.9
HOXB7
homeobox B7
chr10_+_52128343 0.77 ENST00000672084.1
PRKG1
protein kinase cGMP-dependent 1
chr22_+_39901075 0.76 ENST00000344138.9
GRAP2
GRB2 related adaptor protein 2
chr10_-_49188380 0.76 ENST00000374153.7
ENST00000374148.1
ENST00000374151.7
TMEM273
transmembrane protein 273
chr10_-_49188312 0.75 ENST00000453436.5
ENST00000474718.5
TMEM273
transmembrane protein 273
chr9_-_26946983 0.73 ENST00000523212.1
PLAA
phospholipase A2 activating protein
chr3_-_142000353 0.73 ENST00000499676.5
TFDP2
transcription factor Dp-2
chrX_+_108044967 0.72 ENST00000415430.7
VSIG1
V-set and immunoglobulin domain containing 1
chr19_+_47608942 0.71 ENST00000594866.2
BICRA
BRD4 interacting chromatin remodeling complex associated protein
chr2_+_151357583 0.70 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr7_-_44541262 0.65 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr3_+_157436842 0.65 ENST00000295927.4
PTX3
pentraxin 3
chr4_-_119322128 0.65 ENST00000274024.4
FABP2
fatty acid binding protein 2
chr12_-_9869345 0.62 ENST00000228438.3
CLEC2B
C-type lectin domain family 2 member B
chr1_+_170663134 0.62 ENST00000367760.7
PRRX1
paired related homeobox 1
chr11_+_72223918 0.62 ENST00000543234.1
INPPL1
inositol polyphosphate phosphatase like 1
chr2_-_25168571 0.62 ENST00000264708.7
ENST00000449220.1
ENST00000395826.7
POMC
proopiomelanocortin
chr12_-_21910853 0.62 ENST00000544039.5
ABCC9
ATP binding cassette subfamily C member 9
chr19_-_13953302 0.61 ENST00000585607.1
ENST00000538517.6
ENST00000587458.1
ENST00000538371.6
PODNL1
podocan like 1
chr7_+_107583919 0.61 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr18_-_49492305 0.61 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
RPL17
RPL17-C18orf32
ribosomal protein L17
RPL17-C18orf32 readthrough
chr9_-_26947222 0.61 ENST00000520884.5
ENST00000397292.8
PLAA
phospholipase A2 activating protein
chr5_+_40841308 0.59 ENST00000381677.4
ENST00000254691.10
CARD6
caspase recruitment domain family member 6
chr4_+_168497113 0.58 ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr7_-_44541318 0.58 ENST00000381160.8
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr9_+_72577369 0.58 ENST00000651183.1
TMC1
transmembrane channel like 1
chr1_+_157993273 0.58 ENST00000360089.8
ENST00000368173.7
KIRREL1
kirre like nephrin family adhesion molecule 1
chr17_-_445939 0.56 ENST00000329099.4
RFLNB
refilin B
chr15_+_94355956 0.55 ENST00000557742.1
MCTP2
multiple C2 and transmembrane domain containing 2
chr15_+_64387828 0.54 ENST00000261884.8
TRIP4
thyroid hormone receptor interactor 4
chr20_-_35147285 0.54 ENST00000374491.3
ENST00000374492.8
EDEM2
ER degradation enhancing alpha-mannosidase like protein 2
chr13_+_53028806 0.54 ENST00000219022.3
OLFM4
olfactomedin 4
chr17_+_18183803 0.54 ENST00000399138.5
ALKBH5
alkB homolog 5, RNA demethylase
chr12_-_111685720 0.53 ENST00000327551.6
BRAP
BRCA1 associated protein
chr10_-_73655984 0.53 ENST00000394810.3
SYNPO2L
synaptopodin 2 like
chr14_-_53958757 0.52 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr3_+_12287859 0.52 ENST00000309576.11
ENST00000397015.7
PPARG
peroxisome proliferator activated receptor gamma
chr8_-_85341659 0.51 ENST00000522389.5
CA1
carbonic anhydrase 1
chr10_-_93482326 0.50 ENST00000359263.9
MYOF
myoferlin
chr17_+_29941605 0.49 ENST00000394835.7
EFCAB5
EF-hand calcium binding domain 5
chr1_+_77918128 0.49 ENST00000342754.5
NEXN
nexilin F-actin binding protein
chr2_+_233917371 0.49 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr10_-_93482194 0.47 ENST00000358334.9
ENST00000371488.3
MYOF
myoferlin
chr3_+_12287899 0.47 ENST00000643888.2
PPARG
peroxisome proliferator activated receptor gamma
chr12_-_63668803 0.47 ENST00000542209.1
DPY19L2
dpy-19 like 2
chr4_+_112647059 0.46 ENST00000511529.1
LARP7
La ribonucleoprotein 7, transcriptional regulator
chr3_+_45886501 0.46 ENST00000395963.2
CCR9
C-C motif chemokine receptor 9
chr7_+_142554828 0.45 ENST00000611787.1
TRBV11-3
T cell receptor beta variable 11-3
chr20_+_33217325 0.45 ENST00000375452.3
ENST00000375454.8
BPIFA3
BPI fold containing family A member 3
chr8_-_85341705 0.45 ENST00000517618.5
CA1
carbonic anhydrase 1
chr2_+_90234809 0.44 ENST00000443397.5
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr11_+_5689691 0.44 ENST00000425490.5
TRIM22
tripartite motif containing 22
chr9_+_108862255 0.44 ENST00000333999.5
ACTL7A
actin like 7A
chr12_+_10010627 0.44 ENST00000338896.11
ENST00000396502.5
CLEC12B
C-type lectin domain family 12 member B
chr13_-_37598750 0.43 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
POSTN
periostin
chr6_+_3258888 0.43 ENST00000380305.4
PSMG4
proteasome assembly chaperone 4
chr2_-_25168903 0.43 ENST00000405623.5
POMC
proopiomelanocortin
chr2_-_25168690 0.42 ENST00000380794.5
POMC
proopiomelanocortin
chr3_-_185821092 0.41 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr3_+_44799187 0.41 ENST00000425755.5
KIF15
kinesin family member 15
chr21_-_14210948 0.40 ENST00000681601.1
LIPI
lipase I
chr10_-_93482287 0.40 ENST00000371489.5
MYOF
myoferlin
chr6_+_26440472 0.40 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
BTN3A3
butyrophilin subfamily 3 member A3
chr11_-_559377 0.40 ENST00000486629.1
LMNTD2
lamin tail domain containing 2
chr21_-_14210884 0.40 ENST00000679868.1
ENST00000400211.3
ENST00000680801.1
ENST00000536861.6
ENST00000614229.5
LIPI
lipase I
chr12_+_130953898 0.40 ENST00000261654.10
ADGRD1
adhesion G protein-coupled receptor D1
chr3_+_186974957 0.39 ENST00000438590.5
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chrX_-_21758021 0.39 ENST00000646008.1
SMPX
small muscle protein X-linked
chr12_+_71667783 0.39 ENST00000551238.1
THAP2
THAP domain containing 2
chr9_-_74952904 0.38 ENST00000376854.6
C9orf40
chromosome 9 open reading frame 40
chr20_+_45416551 0.38 ENST00000639292.1
PIGT
phosphatidylinositol glycan anchor biosynthesis class T
chr4_+_85604146 0.38 ENST00000512201.5
ARHGAP24
Rho GTPase activating protein 24
chr10_-_28282086 0.37 ENST00000375719.7
ENST00000375732.5
MPP7
membrane palmitoylated protein 7
chrY_+_13703893 0.37 ENST00000284856.4
TMSB4Y
thymosin beta 4 Y-linked
chr5_+_151020438 0.36 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr16_-_28623560 0.36 ENST00000350842.8
SULT1A1
sulfotransferase family 1A member 1
chrX_-_143517473 0.36 ENST00000370503.2
SPANXN3
SPANX family member N3
chr7_-_22822829 0.36 ENST00000358435.9
ENST00000621567.1
TOMM7
translocase of outer mitochondrial membrane 7
chr7_-_22822779 0.35 ENST00000372879.8
TOMM7
translocase of outer mitochondrial membrane 7
chrX_+_135893703 0.35 ENST00000370709.4
SAGE1
sarcoma antigen 1
chr17_+_59155726 0.35 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
PRR11
proline rich 11
chr15_-_19988117 0.35 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr1_+_112718880 0.34 ENST00000361886.4
TAFA3
TAFA chemokine like family member 3
chr1_-_91906280 0.34 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr6_+_47781982 0.34 ENST00000489301.6
ENST00000638973.1
ENST00000371211.6
ENST00000393699.2
OPN5
opsin 5
chr12_+_9971402 0.33 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
CLEC12A
C-type lectin domain family 12 member A
chr6_+_106360668 0.33 ENST00000633556.3
CRYBG1
crystallin beta-gamma domain containing 1
chr20_-_51802433 0.33 ENST00000395997.3
SALL4
spalt like transcription factor 4
chr4_+_107824555 0.33 ENST00000394684.8
SGMS2
sphingomyelin synthase 2
chr20_-_51802509 0.33 ENST00000371539.7
ENST00000217086.9
SALL4
spalt like transcription factor 4
chr18_+_79400274 0.32 ENST00000545796.5
ENST00000318065.9
ENST00000592223.5
ENST00000329101.8
ENST00000586434.1
NFATC1
nuclear factor of activated T cells 1
chr14_-_91780688 0.32 ENST00000556661.5
ENST00000553676.1
ENST00000554560.5
CATSPERB
cation channel sperm associated auxiliary subunit beta
chr12_+_53954870 0.32 ENST00000243103.4
HOXC12
homeobox C12
chr4_+_94207596 0.32 ENST00000359052.8
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_+_57597563 0.32 ENST00000619430.2
ENST00000457869.1
ENST00000340687.10
ENST00000278407.9
ENST00000378323.8
ENST00000378324.6
ENST00000403558.1
SERPING1
serpin family G member 1
chr4_+_70242583 0.31 ENST00000304954.3
CSN3
casein kappa
chr17_+_18183052 0.31 ENST00000541285.1
ALKBH5
alkB homolog 5, RNA demethylase
chr19_+_48445795 0.30 ENST00000598711.1
GRWD1
glutamate rich WD repeat containing 1
chr6_+_155013646 0.30 ENST00000538270.5
ENST00000535231.5
TIAM2
TIAM Rac1 associated GEF 2
chr17_-_40885232 0.29 ENST00000167588.4
KRT20
keratin 20
chr3_+_140678041 0.29 ENST00000286349.4
TRIM42
tripartite motif containing 42
chr19_+_48445961 0.29 ENST00000253237.10
GRWD1
glutamate rich WD repeat containing 1
chr3_-_150703965 0.29 ENST00000498386.1
ERICH6
glutamate rich 6
chr9_-_128724088 0.29 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
ZDHHC12
zinc finger DHHC-type palmitoyltransferase 12
chr17_+_76467597 0.27 ENST00000392492.8
AANAT
aralkylamine N-acetyltransferase
chr11_+_60088657 0.27 ENST00000617306.1
ENST00000278888.8
MS4A2
membrane spanning 4-domains A2
chr2_-_162152404 0.27 ENST00000375497.3
GCG
glucagon
chr12_+_8513499 0.27 ENST00000299665.3
CLEC4D
C-type lectin domain family 4 member D
chr10_+_24466487 0.27 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr6_-_41071825 0.26 ENST00000468811.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr14_-_106211453 0.26 ENST00000390606.3
IGHV3-20
immunoglobulin heavy variable 3-20
chr10_-_101229449 0.26 ENST00000370193.4
LBX1
ladybird homeobox 1
chr20_+_57329801 0.26 ENST00000371263.8
ENST00000345868.8
ENST00000371260.8
ENST00000418127.5
SPO11
SPO11 initiator of meiotic double stranded breaks
chr12_+_9971512 0.26 ENST00000350667.4
CLEC12A
C-type lectin domain family 12 member A
chr11_+_60056587 0.26 ENST00000395032.6
ENST00000358152.6
MS4A3
membrane spanning 4-domains A3
chr6_+_26402237 0.26 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
BTN3A1
butyrophilin subfamily 3 member A1
chr17_-_40937445 0.26 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr16_-_1488764 0.25 ENST00000447419.7
ENST00000440447.2
PTX4
pentraxin 4
chr17_-_9791586 0.25 ENST00000571134.2
DHRS7C
dehydrogenase/reductase 7C
chr7_+_142300924 0.25 ENST00000455382.2
TRBV2
T cell receptor beta variable 2
chr11_+_72223688 0.25 ENST00000540973.1
INPPL1
inositol polyphosphate phosphatase like 1
chrY_-_6872608 0.24 ENST00000383036.1
AMELY
amelogenin Y-linked
chr11_+_92969651 0.24 ENST00000257068.3
ENST00000528076.1
MTNR1B
melatonin receptor 1B
chr12_-_56741535 0.24 ENST00000647707.1
ENSG00000285625.1
novel protein
chr5_+_154941063 0.23 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
MRPL22
mitochondrial ribosomal protein L22
chr1_+_180632001 0.23 ENST00000367590.9
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr15_+_41286011 0.23 ENST00000661438.1
ENSG00000285920.2
novel protein
chr12_-_14961559 0.23 ENST00000228945.9
ENST00000541546.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr20_+_59019397 0.22 ENST00000217133.2
TUBB1
tubulin beta 1 class VI
chr17_-_74776323 0.22 ENST00000582870.5
ENST00000581136.5
ENST00000579218.5
ENST00000583476.5
ENST00000580301.5
ENST00000583757.5
ENST00000357814.8
ENST00000582524.5
NAT9
N-acetyltransferase 9 (putative)
chrX_+_80420466 0.22 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chr12_-_14961610 0.22 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor beta
chr17_-_40937641 0.21 ENST00000209718.8
KRT23
keratin 23
chr10_-_97270638 0.21 ENST00000371027.5
ARHGAP19
Rho GTPase activating protein 19
chr2_+_68734861 0.21 ENST00000467265.5
ARHGAP25
Rho GTPase activating protein 25
chr7_-_5425404 0.21 ENST00000399434.2
TNRC18
trinucleotide repeat containing 18
chr16_+_72054477 0.21 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr19_+_52297157 0.21 ENST00000595962.6
ENST00000598016.5
ENST00000334564.11
ENST00000490272.1
ZNF480
zinc finger protein 480
chr16_+_31259922 0.21 ENST00000648685.1
ENST00000544665.9
ITGAM
integrin subunit alpha M
chr8_-_51809414 0.21 ENST00000356297.5
PXDNL
peroxidasin like
chr17_+_70168610 0.20 ENST00000535240.1
KCNJ2
potassium inwardly rectifying channel subfamily J member 2
chr4_-_39977836 0.20 ENST00000303538.13
ENST00000503396.5
PDS5A
PDS5 cohesin associated factor A
chr1_-_247458105 0.20 ENST00000641149.1
ENST00000641527.1
OR2B11
olfactory receptor family 2 subfamily B member 11

Network of associatons between targets according to the STRING database.

First level regulatory network of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.0 4.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.7 2.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.6 3.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.5 1.4 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.4 2.6 GO:0061760 antifungal innate immune response(GO:0061760)
0.3 1.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 8.5 GO:0003334 keratinocyte development(GO:0003334)
0.3 1.1 GO:0060166 olfactory pit development(GO:0060166)
0.3 1.3 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 1.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.7 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.2 1.5 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.2 1.6 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.2 4.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 0.6 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.2 0.5 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.2 0.9 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.4 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 1.0 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.8 GO:0070378 positive regulation of ERK5 cascade(GO:0070378)
0.1 2.2 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.1 1.0 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.8 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.5 GO:2000007 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.9 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.3 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.7 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:0050955 thermoception(GO:0050955)
0.1 1.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.2 GO:2001025 response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
0.1 1.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 2.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 1.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 1.2 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 1.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 1.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.0 0.2 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.4 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 3.4 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 3.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.6 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 5.2 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.1 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.6 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.3 1.0 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 8.5 GO:0002102 podosome(GO:0002102)
0.1 1.6 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 0.5 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.2 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290) translation initiation ternary complex(GO:0044207)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.9 GO:0043203 axon hillock(GO:0043203)
0.0 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 4.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 2.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 2.9 GO:0005903 brush border(GO:0005903)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 2.7 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0019770 IgG receptor activity(GO:0019770)
0.8 4.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.7 3.4 GO:0004802 transketolase activity(GO:0004802)
0.6 1.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.4 1.3 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.3 11.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.4 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 1.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.9 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 2.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.8 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.1 0.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 4.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.9 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.7 GO:0015266 protein channel activity(GO:0015266)
0.0 2.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.2 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 4.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.7 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 3.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import