Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for OTX1

Z-value: 0.77

Motif logo

logo of

Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.10 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg38_v1_chr2_+_63050813_63050839-0.412.1e-02Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_15686671 2.54 ENST00000262041.6
MEOX2
mesenchyme homeobox 2
chr14_-_106675544 2.52 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr9_+_98943705 2.10 ENST00000610452.1
COL15A1
collagen type XV alpha 1 chain
chr3_+_188947199 1.48 ENST00000433971.5
TPRG1
tumor protein p63 regulated 1
chr1_-_91886144 1.40 ENST00000212355.9
TGFBR3
transforming growth factor beta receptor 3
chr21_+_32298945 1.35 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr19_-_47113756 1.30 ENST00000253048.10
ZC3H4
zinc finger CCCH-type containing 4
chr4_-_137532452 1.30 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr9_+_122370523 1.27 ENST00000643810.1
ENST00000540753.6
PTGS1
prostaglandin-endoperoxide synthase 1
chr7_+_121062765 1.23 ENST00000423795.5
CPED1
cadherin like and PC-esterase domain containing 1
chr16_-_15856994 1.21 ENST00000576790.7
ENST00000396324.7
ENST00000300036.6
ENST00000452625.7
MYH11
myosin heavy chain 11
chr16_-_55833186 1.17 ENST00000361503.8
ENST00000422046.6
CES1
carboxylesterase 1
chr9_-_92482499 1.16 ENST00000375544.7
ASPN
asporin
chr19_+_50854910 1.11 ENST00000601503.5
ENST00000326003.7
ENST00000617027.4
ENST00000597286.5
ENST00000597483.5
ENST00000593997.5
KLK3
kallikrein related peptidase 3
chr9_-_92482350 1.00 ENST00000375543.2
ASPN
asporin
chr14_-_106005574 1.00 ENST00000390595.3
IGHV1-3
immunoglobulin heavy variable 1-3
chr6_+_33391805 0.99 ENST00000428849.7
ENST00000450504.1
KIFC1
kinesin family member C1
chr19_+_50854938 0.98 ENST00000595952.5
ENST00000360617.7
ENST00000598145.1
KLK3
kallikrein related peptidase 3
chr14_-_106511856 0.95 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr6_+_35452314 0.95 ENST00000229769.3
FANCE
FA complementation group E
chr22_+_22369601 0.94 ENST00000390295.3
IGLV7-46
immunoglobulin lambda variable 7-46
chr3_-_149377637 0.94 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr19_-_42412347 0.92 ENST00000601189.1
ENST00000599211.1
LIPE
lipase E, hormone sensitive type
chr7_+_120988683 0.92 ENST00000340646.9
ENST00000310396.10
CPED1
cadherin like and PC-esterase domain containing 1
chr9_-_92482461 0.90 ENST00000651738.1
ASPN
asporin
chr1_+_34792990 0.88 ENST00000450137.1
ENST00000342280.5
GJA4
gap junction protein alpha 4
chr13_+_24309565 0.88 ENST00000332018.4
C1QTNF9
C1q and TNF related 9
chr12_-_9115907 0.83 ENST00000318602.12
A2M
alpha-2-macroglobulin
chr6_-_32763466 0.81 ENST00000427449.1
ENST00000411527.5
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr9_-_35563867 0.81 ENST00000399742.7
ENST00000619051.4
FAM166B
family with sequence similarity 166 member B
chr11_+_8683201 0.78 ENST00000526562.5
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr19_-_3761657 0.78 ENST00000316757.4
APBA3
amyloid beta precursor protein binding family A member 3
chrX_+_101390824 0.77 ENST00000427805.6
ENST00000614077.4
RPL36A
ribosomal protein L36a
chr16_+_68085552 0.77 ENST00000329524.8
NFATC3
nuclear factor of activated T cells 3
chr2_-_189583392 0.75 ENST00000440626.1
SLC40A1
solute carrier family 40 member 1
chr14_-_106724093 0.74 ENST00000390634.3
IGHV2-70D
immunoglobulin heavy variable 2-70D
chr17_-_38825303 0.74 ENST00000614790.5
CWC25
CWC25 spliceosome associated protein homolog
chr17_+_59940908 0.73 ENST00000591035.1
ENSG00000267318.1
novel protein
chr3_-_69013639 0.73 ENST00000456376.2
ENST00000383701.8
EOGT
EGF domain specific O-linked N-acetylglucosamine transferase
chr15_-_19988117 0.73 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_+_102104563 0.72 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr16_-_54286763 0.71 ENST00000329734.4
IRX3
iroquois homeobox 3
chr14_-_89412025 0.69 ENST00000553840.5
ENST00000556916.5
FOXN3
forkhead box N3
chr3_-_69013612 0.68 ENST00000295571.9
EOGT
EGF domain specific O-linked N-acetylglucosamine transferase
chr8_-_56074144 0.67 ENST00000618656.2
RPS20
ribosomal protein S20
chr3_+_138621225 0.64 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_138621207 0.63 ENST00000464668.5
FAIM
Fas apoptotic inhibitory molecule
chr1_-_16212598 0.63 ENST00000270747.8
ARHGEF19
Rho guanine nucleotide exchange factor 19
chr5_+_111071710 0.62 ENST00000344895.4
TSLP
thymic stromal lymphopoietin
chr1_+_160739286 0.62 ENST00000359331.8
ENST00000495334.1
SLAMF7
SLAM family member 7
chr16_-_21440719 0.61 ENST00000521589.5
NPIPB3
nuclear pore complex interacting protein family member B3
chr1_+_86993009 0.59 ENST00000370548.3
ENSG00000267561.2
novel protein
chr19_-_38975687 0.57 ENST00000292852.9
FBXO17
F-box protein 17
chr16_-_21652598 0.57 ENST00000569602.1
ENST00000268389.6
IGSF6
immunoglobulin superfamily member 6
chr1_+_24556087 0.56 ENST00000374392.3
NCMAP
non-compact myelin associated protein
chr6_-_130890393 0.56 ENST00000456097.6
EPB41L2
erythrocyte membrane protein band 4.1 like 2
chr14_-_106803221 0.56 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr3_-_71132099 0.55 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
FOXP1
forkhead box P1
chr2_+_169479445 0.55 ENST00000513963.1
ENST00000392663.6
ENST00000295240.8
ENSG00000251569.1
BBS5
novel protein
Bardet-Biedl syndrome 5
chr11_-_67508091 0.54 ENST00000531506.1
CDK2AP2
cyclin dependent kinase 2 associated protein 2
chr5_-_39425187 0.54 ENST00000545653.5
DAB2
DAB adaptor protein 2
chr4_+_99816797 0.51 ENST00000512369.2
ENST00000296414.11
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr14_-_106301848 0.50 ENST00000390611.2
IGHV2-26
immunoglobulin heavy variable 2-26
chr18_-_80247348 0.50 ENST00000470488.2
ENST00000353265.8
PARD6G
par-6 family cell polarity regulator gamma
chr1_-_16156059 0.50 ENST00000358432.8
EPHA2
EPH receptor A2
chr18_+_23689439 0.49 ENST00000313654.14
LAMA3
laminin subunit alpha 3
chr3_+_136930469 0.48 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr4_-_82848843 0.48 ENST00000511338.1
SEC31A
SEC31 homolog A, COPII coat complex component
chr1_-_53142577 0.46 ENST00000620347.5
ENST00000611397.5
SLC1A7
solute carrier family 1 member 7
chr3_+_155083523 0.46 ENST00000680057.1
MME
membrane metalloendopeptidase
chrX_-_135022473 0.46 ENST00000391440.3
RTL8B
retrotransposon Gag like 8B
chr13_+_23180960 0.45 ENST00000218867.4
SGCG
sarcoglycan gamma
chr16_-_29862890 0.45 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr6_+_106098933 0.44 ENST00000369089.3
PRDM1
PR/SET domain 1
chr10_+_24466487 0.44 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr1_+_174875505 0.42 ENST00000486220.5
RABGAP1L
RAB GTPase activating protein 1 like
chr11_-_67508152 0.42 ENST00000301488.8
CDK2AP2
cyclin dependent kinase 2 associated protein 2
chr20_+_3071618 0.41 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr16_+_33802683 0.41 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_+_109898685 0.38 ENST00000480744.2
LIMS3
LIM zinc finger domain containing 3
chr6_-_34426052 0.38 ENST00000344700.8
ENST00000644700.1
ENST00000648437.1
ENST00000644393.1
ENST00000639725.1
RPS10
RPS10-NUDT3
ribosomal protein S10
RPS10-NUDT3 readthrough
chrX_-_15315615 0.37 ENST00000380470.7
ENST00000480796.6
ASB11
ankyrin repeat and SOCS box containing 11
chr10_+_112374110 0.37 ENST00000354655.9
ACSL5
acyl-CoA synthetase long chain family member 5
chr17_-_8867639 0.36 ENST00000619866.5
PIK3R6
phosphoinositide-3-kinase regulatory subunit 6
chr17_-_35560812 0.35 ENST00000674182.1
SLFN14
schlafen family member 14
chr1_-_28643005 0.35 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TAF12
TATA-box binding protein associated factor 12
chr1_+_150321523 0.34 ENST00000324862.7
PRPF3
pre-mRNA processing factor 3
chr2_-_105438503 0.34 ENST00000393352.7
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr6_+_42050876 0.34 ENST00000465926.5
ENST00000482432.1
TAF8
TATA-box binding protein associated factor 8
chr17_-_36001549 0.34 ENST00000617897.2
CCL15
C-C motif chemokine ligand 15
chr14_-_26598025 0.33 ENST00000539517.7
NOVA1
NOVA alternative splicing regulator 1
chr1_-_53142617 0.33 ENST00000371491.4
ENST00000371494.9
SLC1A7
solute carrier family 1 member 7
chr19_+_16197900 0.33 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
AP1M1
adaptor related protein complex 1 subunit mu 1
chr6_-_34426020 0.32 ENST00000621356.3
ENST00000494077.6
ENST00000639877.1
RPS10
RPS10-NUDT3
ribosomal protein S10
RPS10-NUDT3 readthrough
chr17_+_43006740 0.31 ENST00000438323.2
ENST00000415816.7
IFI35
interferon induced protein 35
chr14_+_20110739 0.31 ENST00000641386.2
ENST00000641633.2
OR4K17
olfactory receptor family 4 subfamily K member 17
chr21_+_42653734 0.31 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
PDE9A
phosphodiesterase 9A
chr5_+_136160986 0.30 ENST00000507637.1
SMAD5
SMAD family member 5
chr5_-_55692620 0.30 ENST00000503817.5
ENST00000512595.5
SLC38A9
solute carrier family 38 member 9
chr8_+_22275309 0.30 ENST00000356766.11
ENST00000521356.5
PIWIL2
piwi like RNA-mediated gene silencing 2
chr17_-_73227700 0.30 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104 member A
chr19_+_13151975 0.30 ENST00000588173.1
IER2
immediate early response 2
chr16_-_29404029 0.29 ENST00000524087.5
NPIPB11
nuclear pore complex interacting protein family member B11
chr14_-_26597430 0.27 ENST00000344429.9
ENST00000574031.1
ENST00000465357.6
ENST00000547619.5
NOVA1
NOVA alternative splicing regulator 1
chr19_+_34428353 0.26 ENST00000590048.6
ENST00000246548.9
UBA2
ubiquitin like modifier activating enzyme 2
chr16_-_66549770 0.26 ENST00000677715.1
ENST00000525974.5
TK2
thymidine kinase 2
chr10_-_34815257 0.26 ENST00000374789.8
ENST00000374788.8
ENST00000346874.9
ENST00000374794.8
ENST00000350537.9
ENST00000374790.8
ENST00000374776.6
ENST00000374773.6
ENST00000545260.5
ENST00000545693.5
ENST00000340077.9
PARD3
par-3 family cell polarity regulator
chr2_-_159798234 0.26 ENST00000429078.6
ENST00000553424.5
CD302
CD302 molecule
chr16_-_29863117 0.26 ENST00000566113.5
ENST00000569956.5
ENST00000570016.5
ENST00000219789.11
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr16_-_21857657 0.26 ENST00000341400.11
ENST00000518761.8
ENST00000682606.1
NPIPB4
nuclear pore complex interacting protein family member B4
chr19_+_47113425 0.26 ENST00000594526.5
SAE1
SUMO1 activating enzyme subunit 1
chr19_-_51108365 0.26 ENST00000421832.3
CTU1
cytosolic thiouridylase subunit 1
chr19_+_17337539 0.25 ENST00000324894.13
ENST00000358792.11
ENST00000600625.5
GTPBP3
GTP binding protein 3, mitochondrial
chr1_+_81306096 0.25 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
ADGRL2
adhesion G protein-coupled receptor L2
chr6_-_144095556 0.25 ENST00000367569.4
SF3B5
splicing factor 3b subunit 5
chr1_-_15976114 0.24 ENST00000375733.6
ZBTB17
zinc finger and BTB domain containing 17
chr17_-_7234262 0.24 ENST00000575756.5
ENST00000575458.5
DVL2
dishevelled segment polarity protein 2
chr5_+_96702849 0.24 ENST00000508197.1
CAST
calpastatin
chr19_+_35449584 0.24 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr16_-_21425278 0.23 ENST00000504841.6
ENST00000419180.6
NPIPB3
nuclear pore complex interacting protein family member B3
chr14_+_77116562 0.23 ENST00000557408.5
TMEM63C
transmembrane protein 63C
chr4_-_121823843 0.23 ENST00000274026.10
CCNA2
cyclin A2
chr6_-_31680377 0.23 ENST00000383237.4
LY6G5C
lymphocyte antigen 6 family member G5C
chr19_+_16197848 0.22 ENST00000590263.5
ENST00000590756.5
AP1M1
adaptor related protein complex 1 subunit mu 1
chr16_-_66549839 0.22 ENST00000527800.6
ENST00000677555.1
ENST00000563369.6
TK2
thymidine kinase 2
chr16_-_69339493 0.22 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
COG8
component of oligomeric golgi complex 8
chr4_-_47981535 0.21 ENST00000402813.9
CNGA1
cyclic nucleotide gated channel subunit alpha 1
chr19_-_53159004 0.21 ENST00000599096.1
ENST00000597183.5
ENST00000601804.5
ENST00000334197.12
ENST00000601469.2
ENST00000452676.6
ZNF347
zinc finger protein 347
chr1_+_224356852 0.21 ENST00000366858.7
ENST00000366857.9
ENST00000465271.6
ENST00000366856.3
CNIH4
cornichon family AMPA receptor auxiliary protein 4
chr4_+_74308463 0.21 ENST00000413830.6
EPGN
epithelial mitogen
chr11_+_124012997 0.21 ENST00000641521.1
ENST00000641722.1
OR10G4
olfactory receptor family 10 subfamily G member 4
chr9_+_21802628 0.21 ENST00000644715.2
ENST00000460874.6
ENST00000580900.5
MTAP
methylthioadenosine phosphorylase
chr15_+_42495253 0.20 ENST00000349777.5
SNAP23
synaptosome associated protein 23
chr1_+_184051678 0.20 ENST00000643231.1
TSEN15
tRNA splicing endonuclease subunit 15
chr1_-_216423396 0.20 ENST00000366942.3
ENST00000674083.1
ENST00000307340.8
USH2A
usherin
chr22_+_38656627 0.19 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
CBY1
chibby family member 1, beta catenin antagonist
chr11_+_119334511 0.19 ENST00000311413.5
RNF26
ring finger protein 26
chr1_-_92075441 0.19 ENST00000596516.2
SETSIP
SET like protein
chr11_-_112086727 0.18 ENST00000504148.3
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B
chr1_-_15976070 0.18 ENST00000537142.5
ENST00000375743.9
ZBTB17
zinc finger and BTB domain containing 17
chr15_-_61229297 0.18 ENST00000335670.11
RORA
RAR related orphan receptor A
chr16_-_66550005 0.18 ENST00000527284.6
TK2
thymidine kinase 2
chr11_-_85665077 0.17 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr1_+_247549002 0.17 ENST00000366488.5
GCSAML
germinal center associated signaling and motility like
chr1_-_154956086 0.17 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBXIP1
PBX homeobox interacting protein 1
chr20_+_9166322 0.17 ENST00000416836.5
PLCB4
phospholipase C beta 4
chr5_-_60488055 0.16 ENST00000505507.6
ENST00000515835.2
ENST00000502484.6
PDE4D
phosphodiesterase 4D
chr19_-_10420121 0.16 ENST00000593124.1
CDC37
cell division cycle 37, HSP90 cochaperone
chr19_-_15815664 0.16 ENST00000641419.1
OR10H1
olfactory receptor family 10 subfamily H member 1
chr11_-_67443459 0.16 ENST00000341356.10
ENST00000627576.2
CORO1B
coronin 1B
chr8_-_78805515 0.16 ENST00000379113.6
ENST00000541183.2
IL7
interleukin 7
chr3_-_98901155 0.16 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr2_-_85410336 0.15 ENST00000263867.9
ENST00000409921.5
CAPG
capping actin protein, gelsolin like
chr5_-_82278396 0.14 ENST00000510019.5
RPS23
ribosomal protein S23
chr5_-_82278341 0.14 ENST00000510210.5
ENST00000512493.5
ENST00000296674.13
ENST00000507980.1
ENST00000511844.1
ENST00000651545.1
RPS23
ribosomal protein S23
chr2_-_24084822 0.14 ENST00000238721.9
TP53I3
tumor protein p53 inducible protein 3
chr1_+_243256034 0.13 ENST00000366541.8
SDCCAG8
SHH signaling and ciliogenesis regulator SDCCAG8
chr19_+_10271093 0.13 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
ICAM1
intercellular adhesion molecule 1
chr2_-_159798043 0.13 ENST00000664982.1
ENST00000259053.6
ENSG00000287091.1
CD302
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr12_-_53677397 0.13 ENST00000338662.6
ENST00000552242.5
ATP5MC2
ATP synthase membrane subunit c locus 2
chr6_-_127342398 0.13 ENST00000531582.1
ECHDC1
ethylmalonyl-CoA decarboxylase 1
chr5_+_148063971 0.12 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
SPINK5
serine peptidase inhibitor Kazal type 5
chr4_+_75513885 0.12 ENST00000506261.5
THAP6
THAP domain containing 6
chr14_-_24442241 0.12 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
SDR39U1
short chain dehydrogenase/reductase family 39U member 1
chr8_+_142700095 0.12 ENST00000292430.10
ENST00000518841.5
ENST00000519387.1
LY6K
lymphocyte antigen 6 family member K
chr15_+_101812202 0.12 ENST00000332238.5
OR4F15
olfactory receptor family 4 subfamily F member 15
chr13_+_113548303 0.12 ENST00000620021.4
TMCO3
transmembrane and coiled-coil domains 3
chr13_+_97960192 0.12 ENST00000496368.6
ENST00000421861.7
ENST00000357602.7
IPO5
importin 5
chr17_-_81656532 0.12 ENST00000331056.10
PDE6G
phosphodiesterase 6G
chr12_-_4645150 0.12 ENST00000536414.3
AKAP3
A-kinase anchoring protein 3
chr4_+_1712821 0.11 ENST00000458173.4
TACC3
transforming acidic coiled-coil containing protein 3
chr3_-_142029108 0.11 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr5_-_147906530 0.11 ENST00000318315.5
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr1_-_54887161 0.11 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
DHCR24
24-dehydrocholesterol reductase
chr6_-_132734692 0.11 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
VNN3
vanin 3
chr3_-_11643871 0.10 ENST00000430365.7
VGLL4
vestigial like family member 4
chr4_+_186144824 0.10 ENST00000227065.8
ENST00000502970.5
ENST00000514153.5
FAM149A
family with sequence similarity 149 member A
chr7_-_101252133 0.10 ENST00000435848.1
ENST00000474120.5
FIS1
fission, mitochondrial 1
chr21_-_30755428 0.10 ENST00000335093.5
KRTAP21-1
keratin associated protein 21-1
chr17_-_8376658 0.10 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRBA2
KRAB-A domain containing 2
chr16_+_14708944 0.10 ENST00000526520.5
ENST00000531598.6
NPIPA3
nuclear pore complex interacting protein family member A3
chr14_+_21736136 0.09 ENST00000390426.2
TRAV4
T cell receptor alpha variable 4
chr17_-_41168219 0.09 ENST00000391356.4
KRTAP4-3
keratin associated protein 4-3
chr15_-_68229658 0.09 ENST00000565471.6
ENST00000637494.1
ENST00000636314.1
ENST00000637667.1
ENST00000564752.1
ENST00000566347.5
ENST00000249806.11
ENST00000562767.2
CLN6
ENSG00000260007.3
CLN6 transmembrane ER protein
novel protein
chr14_-_34714579 0.09 ENST00000298159.11
CFL2
cofilin 2
chr6_+_70566892 0.09 ENST00000370474.4
SDHAF4
succinate dehydrogenase complex assembly factor 4
chr17_-_28549333 0.09 ENST00000470125.5
UNC119
unc-119 lipid binding chaperone
chrX_+_80420466 0.08 ENST00000308293.5
TENT5D
terminal nucleotidyltransferase 5D
chrX_+_7219431 0.08 ENST00000674499.1
ENST00000217961.5
STS
steroid sulfatase
chr8_+_54616078 0.08 ENST00000220676.2
RP1
RP1 axonemal microtubule associated
chr1_-_165698863 0.07 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family member A1
chr5_+_134967901 0.07 ENST00000282611.8
CATSPER3
cation channel sperm associated 3
chr16_+_10866199 0.07 ENST00000637439.1
CIITA
class II major histocompatibility complex transactivator
chr12_+_6494087 0.06 ENST00000382457.8
ENST00000315579.10
NCAPD2
non-SMC condensin I complex subunit D2
chr1_-_160862880 0.06 ENST00000368034.9
CD244
CD244 molecule
chr17_-_4786354 0.06 ENST00000328739.6
ENST00000441199.2
ENST00000416307.6
VMO1
vitelline membrane outer layer 1 homolog
chr5_+_111092329 0.05 ENST00000513710.4
WDR36
WD repeat domain 36
chr22_-_38656353 0.05 ENST00000535113.7
FAM227A
family with sequence similarity 227 member A
chr4_-_107283689 0.05 ENST00000513208.5
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr6_+_38722810 0.04 ENST00000449981.6
DNAH8
dynein axonemal heavy chain 8

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0001757 somite specification(GO:0001757)
0.4 3.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 1.2 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.3 1.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 0.7 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2 0.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 2.2 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.2 0.5 GO:1901491 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.5 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.9 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.4 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.4 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 0.7 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 0.5 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 1.0 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.7 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.2 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 6.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.8 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0071287 cellular response to magnesium ion(GO:0071286) cellular response to manganese ion(GO:0071287)
0.0 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 2.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 1.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.9 GO:0048265 response to pain(GO:0048265)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 2.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 6.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:1990696 stereocilia ankle link(GO:0002141) USH2 complex(GO:1990696)
0.1 0.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0043220 paranode region of axon(GO:0033270) Schmidt-Lanterman incisure(GO:0043220)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.5 1.4 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 0.9 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.7 GO:0097689 iron channel activity(GO:0097689)
0.2 1.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.5 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.8 GO:0043120 interleukin-8 binding(GO:0019959) tumor necrosis factor binding(GO:0043120)
0.1 0.7 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 6.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.7 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.7 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:0005139 interleukin-7 receptor binding(GO:0005139)
0.1 0.3 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.6 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 2.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 3.3 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 3.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME KINESINS Genes involved in Kinesins
0.0 3.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters