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Illumina Body Map 2 (GSE30611)

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Results for OTX2_CRX

Z-value: 0.85

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.18 orthodenticle homeobox 2
CRX
ENSG00000105392.16 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX2hg38_v1_chr14_-_56810380_568103980.421.8e-02Click!
CRXhg38_v1_chr19_+_47821907_47821964-0.115.5e-01Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_34710249 4.91 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
DTNA
dystrobrevin alpha
chr7_+_74453790 3.06 ENST00000265755.7
ENST00000424337.7
ENST00000455841.6
GTF2IRD1
GTF2I repeat domain containing 1
chr2_+_219491867 2.87 ENST00000412982.5
ENSG00000286143.1
novel protein
chrX_-_21658324 2.72 ENST00000379499.3
KLHL34
kelch like family member 34
chr2_+_169509693 2.42 ENST00000284669.2
KLHL41
kelch like family member 41
chr15_+_86079863 2.41 ENST00000614907.3
ENST00000441037.7
AGBL1
ATP/GTP binding protein like 1
chr5_-_150289764 2.21 ENST00000671881.1
ENST00000672752.1
ENST00000510347.2
ENST00000672829.1
ENST00000348628.11
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr7_+_123655857 2.11 ENST00000458573.3
ENST00000456238.2
LMOD2
leiomodin 2
chr5_-_88883147 2.04 ENST00000513252.5
ENST00000506554.5
ENST00000508569.5
ENST00000637732.1
ENST00000504921.7
ENST00000637481.1
ENST00000510942.5
MEF2C
myocyte enhancer factor 2C
chr5_-_150289625 2.00 ENST00000683332.1
ENST00000398376.8
ENST00000672785.1
ENST00000672396.1
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr3_-_179974078 1.90 ENST00000464614.5
ENST00000476138.5
ENST00000463761.1
PEX5L
peroxisomal biogenesis factor 5 like
chr12_+_80707625 1.83 ENST00000228641.4
MYF6
myogenic factor 6
chr18_+_34710307 1.82 ENST00000679796.1
DTNA
dystrobrevin alpha
chr10_-_114658268 1.70 ENST00000649363.1
ENST00000277895.9
ABLIM1
actin binding LIM protein 1
chr6_-_139291987 1.65 ENST00000358430.8
TXLNB
taxilin beta
chr6_+_34466059 1.65 ENST00000620693.4
ENST00000244458.7
ENST00000374043.6
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr5_-_88883199 1.64 ENST00000514015.5
ENST00000503075.1
MEF2C
myocyte enhancer factor 2C
chr2_-_174846405 1.60 ENST00000409597.5
ENST00000413882.6
CHN1
chimerin 1
chr3_+_50611871 1.53 ENST00000446044.5
MAPKAPK3
MAPK activated protein kinase 3
chr15_-_26939518 1.50 ENST00000541819.6
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr10_-_75109172 1.48 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
DUSP13
dual specificity phosphatase 13
chrX_+_136197020 1.47 ENST00000370676.7
FHL1
four and a half LIM domains 1
chr5_-_88883420 1.47 ENST00000437473.6
MEF2C
myocyte enhancer factor 2C
chr1_-_165445088 1.41 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr22_-_37984534 1.39 ENST00000396884.8
SOX10
SRY-box transcription factor 10
chr2_+_218607914 1.34 ENST00000417849.5
PLCD4
phospholipase C delta 4
chr1_+_202462730 1.30 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chrX_-_15600953 1.27 ENST00000679212.1
ENST00000679278.1
ENST00000678046.1
ENST00000252519.8
ACE2
angiotensin I converting enzyme 2
chr6_-_42722590 1.26 ENST00000230381.7
PRPH2
peripherin 2
chr3_-_179974254 1.26 ENST00000468741.5
PEX5L
peroxisomal biogenesis factor 5 like
chr11_-_72041945 1.25 ENST00000543009.5
NUMA1
nuclear mitotic apparatus protein 1
chr1_+_18630839 1.23 ENST00000420770.7
PAX7
paired box 7
chr18_-_24311495 1.22 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr2_-_174847015 1.21 ENST00000650938.1
CHN1
chimerin 1
chr18_-_66604076 1.19 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
CDH19
cadherin 19
chr5_-_150289941 1.18 ENST00000682786.1
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr11_-_111923722 1.17 ENST00000527950.5
CRYAB
crystallin alpha B
chrX_-_15601077 1.13 ENST00000680121.1
ACE2
angiotensin I converting enzyme 2
chr10_+_17951906 1.13 ENST00000377371.3
ENST00000377369.7
SLC39A12
solute carrier family 39 member 12
chr5_+_162067458 1.07 ENST00000639975.1
ENST00000639111.2
ENST00000639683.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_-_154247630 1.07 ENST00000519344.5
IPCEF1
interaction protein for cytohesin exchange factors 1
chr10_-_75109085 1.06 ENST00000607131.5
DUSP13
dual specificity phosphatase 13
chr10_+_17951825 1.04 ENST00000539911.5
SLC39A12
solute carrier family 39 member 12
chrX_+_136197039 1.04 ENST00000370683.6
FHL1
four and a half LIM domains 1
chr14_-_93955258 1.04 ENST00000556062.5
ASB2
ankyrin repeat and SOCS box containing 2
chr4_-_110636963 1.03 ENST00000394595.8
PITX2
paired like homeodomain 2
chr9_+_100442271 1.03 ENST00000502978.1
MSANTD3-TMEFF1
MSANTD3-TMEFF1 readthrough
chr5_-_41794211 1.02 ENST00000512084.5
OXCT1
3-oxoacid CoA-transferase 1
chr11_-_72041522 1.01 ENST00000544238.5
NUMA1
nuclear mitotic apparatus protein 1
chr5_-_88883701 1.00 ENST00000636998.1
MEF2C
myocyte enhancer factor 2C
chr7_+_123601815 1.00 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr5_-_150290093 1.00 ENST00000672479.1
CAMK2A
calcium/calmodulin dependent protein kinase II alpha
chr1_-_201112420 0.99 ENST00000362061.4
ENST00000681874.1
CACNA1S
calcium voltage-gated channel subunit alpha1 S
chr10_+_17951885 0.98 ENST00000377374.8
SLC39A12
solute carrier family 39 member 12
chr4_-_101346842 0.98 ENST00000507176.5
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr13_+_35476740 0.96 ENST00000537702.5
NBEA
neurobeachin
chr2_+_218607861 0.95 ENST00000450993.7
PLCD4
phospholipase C delta 4
chr1_-_165445220 0.95 ENST00000619224.1
RXRG
retinoid X receptor gamma
chr7_+_123601836 0.95 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr11_-_111912871 0.94 ENST00000528628.5
CRYAB
crystallin alpha B
chr15_+_33310946 0.94 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
RYR3
ryanodine receptor 3
chrX_+_136196750 0.92 ENST00000539015.5
FHL1
four and a half LIM domains 1
chr12_-_54981838 0.91 ENST00000316577.12
TESPA1
thymocyte expressed, positive selection associated 1
chr1_+_244051275 0.91 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr8_+_53851786 0.90 ENST00000297313.8
ENST00000344277.10
RGS20
regulator of G protein signaling 20
chr13_-_61427849 0.89 ENST00000409186.1
ENST00000472649.2
ENSG00000197991.11
LINC02339
novel protein
long intergenic non-protein coding RNA 2339
chr5_+_162067764 0.88 ENST00000639213.2
ENST00000414552.6
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr4_-_101347551 0.87 ENST00000525819.1
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr3_+_49021071 0.87 ENST00000395458.6
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr1_-_117121692 0.85 ENST00000256649.9
ENST00000369464.7
ENST00000485032.1
TRIM45
tripartite motif containing 45
chrM_+_8366 0.85 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase membrane subunit 8
chr11_-_72041792 0.84 ENST00000537930.5
NUMA1
nuclear mitotic apparatus protein 1
chr5_-_150758497 0.84 ENST00000521533.1
ENST00000424236.5
DCTN4
dynactin subunit 4
chr7_+_30145789 0.84 ENST00000324489.5
MTURN
maturin, neural progenitor differentiation regulator homolog
chr7_-_33040893 0.83 ENST00000643244.1
ENST00000409467.6
ENST00000449201.5
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr10_+_94089067 0.80 ENST00000371375.1
ENST00000675218.1
PLCE1
phospholipase C epsilon 1
chr5_-_96433214 0.79 ENST00000311106.8
PCSK1
proprotein convertase subtilisin/kexin type 1
chr10_+_94089034 0.79 ENST00000676102.1
ENST00000371385.8
PLCE1
phospholipase C epsilon 1
chrX_-_32412220 0.78 ENST00000619831.5
DMD
dystrophin
chr9_+_34992849 0.78 ENST00000443266.2
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5
chr13_-_35476682 0.78 ENST00000379919.6
MAB21L1
mab-21 like 1
chr5_-_88824334 0.77 ENST00000506716.5
MEF2C
myocyte enhancer factor 2C
chr7_+_123601859 0.73 ENST00000437535.5
ASB15
ankyrin repeat and SOCS box containing 15
chr12_+_40393392 0.72 ENST00000676020.1
MUC19
mucin 19, oligomeric
chr10_-_75109106 0.68 ENST00000607487.5
DUSP13
dual specificity phosphatase 13
chr14_-_100568070 0.65 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
BEGAIN
brain enriched guanylate kinase associated
chr5_+_150660841 0.61 ENST00000297130.4
MYOZ3
myozenin 3
chr8_-_42502496 0.61 ENST00000522707.1
SLC20A2
solute carrier family 20 member 2
chr18_-_72865680 0.61 ENST00000397929.5
NETO1
neuropilin and tolloid like 1
chr3_+_69866217 0.61 ENST00000314589.10
MITF
melanocyte inducing transcription factor
chr5_-_24644968 0.60 ENST00000264463.8
CDH10
cadherin 10
chr2_-_224497816 0.60 ENST00000451538.1
CUL3
cullin 3
chrM_+_8489 0.59 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase membrane subunit 6
chr5_+_102864505 0.58 ENST00000511839.5
PAM
peptidylglycine alpha-amidating monooxygenase
chr10_+_24239181 0.57 ENST00000438429.5
KIAA1217
KIAA1217
chr1_+_159171607 0.57 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
CADM3
cell adhesion molecule 3
chrX_+_28587411 0.56 ENST00000378993.6
IL1RAPL1
interleukin 1 receptor accessory protein like 1
chr17_-_45132505 0.55 ENST00000619929.5
PLCD3
phospholipase C delta 3
chr3_+_69866236 0.54 ENST00000451708.5
MITF
melanocyte inducing transcription factor
chr12_-_14696571 0.54 ENST00000261170.5
GUCY2C
guanylate cyclase 2C
chr5_-_88824266 0.53 ENST00000509373.1
ENST00000636541.1
MEF2C
myocyte enhancer factor 2C
chr7_+_136869077 0.52 ENST00000320658.9
ENST00000453373.5
ENST00000401861.1
CHRM2
cholinergic receptor muscarinic 2
chr10_-_67696115 0.51 ENST00000433211.7
CTNNA3
catenin alpha 3
chr9_+_12693327 0.51 ENST00000388918.10
TYRP1
tyrosinase related protein 1
chr4_-_101347327 0.50 ENST00000394853.8
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr8_+_103880412 0.49 ENST00000436393.6
RIMS2
regulating synaptic membrane exocytosis 2
chr16_-_57971121 0.49 ENST00000251102.13
CNGB1
cyclic nucleotide gated channel subunit beta 1
chr11_-_41459592 0.48 ENST00000528697.6
ENST00000530763.5
LRRC4C
leucine rich repeat containing 4C
chr21_-_18403754 0.48 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr11_-_72041054 0.47 ENST00000542977.5
NUMA1
nuclear mitotic apparatus protein 1
chr2_+_161624406 0.47 ENST00000446997.6
ENST00000272716.9
SLC4A10
solute carrier family 4 member 10
chr7_+_28412511 0.47 ENST00000357727.7
CREB5
cAMP responsive element binding protein 5
chr18_-_43277482 0.46 ENST00000255224.8
ENST00000590752.5
ENST00000596867.1
SYT4
synaptotagmin 4
chr18_-_37565628 0.45 ENST00000334919.9
ENST00000591282.5
ENST00000588597.5
CELF4
CUGBP Elav-like family member 4
chr9_-_28670285 0.45 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
LINGO2
leucine rich repeat and Ig domain containing 2
chr11_-_72040694 0.45 ENST00000535947.5
NUMA1
nuclear mitotic apparatus protein 1
chr5_-_11589019 0.45 ENST00000511377.5
CTNND2
catenin delta 2
chr18_-_37565714 0.45 ENST00000591287.5
ENST00000601019.5
ENST00000601392.5
CELF4
CUGBP Elav-like family member 4
chr10_-_114632011 0.44 ENST00000651023.1
ABLIM1
actin binding LIM protein 1
chr14_-_22926413 0.44 ENST00000556043.5
PRMT5
protein arginine methyltransferase 5
chr5_+_162067500 0.44 ENST00000639384.1
ENST00000640985.1
ENST00000638772.1
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chr1_+_164559173 0.44 ENST00000420696.7
PBX1
PBX homeobox 1
chr1_+_205257180 0.44 ENST00000330675.12
TMCC2
transmembrane and coiled-coil domain family 2
chr10_+_50990864 0.44 ENST00000401604.8
PRKG1
protein kinase cGMP-dependent 1
chr3_+_173584433 0.43 ENST00000361589.8
NLGN1
neuroligin 1
chr5_-_11588842 0.43 ENST00000503622.5
CTNND2
catenin delta 2
chr9_+_85941121 0.42 ENST00000361671.10
NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr2_-_212124901 0.42 ENST00000402597.6
ERBB4
erb-b2 receptor tyrosine kinase 4
chr15_+_62758585 0.42 ENST00000472902.1
TLN2
talin 2
chr1_+_164559766 0.42 ENST00000367897.5
ENST00000559240.5
PBX1
PBX homeobox 1
chr10_-_125028061 0.42 ENST00000309035.11
CTBP2
C-terminal binding protein 2
chr11_+_63681573 0.42 ENST00000354497.4
RTN3
reticulon 3
chr11_-_47499757 0.42 ENST00000535982.1
CELF1
CUGBP Elav-like family member 1
chr1_+_164559739 0.42 ENST00000627490.2
PBX1
PBX homeobox 1
chr15_+_33310993 0.41 ENST00000634418.1
ENST00000634750.1
RYR3
ryanodine receptor 3
chr10_-_84241538 0.41 ENST00000372105.4
LRIT1
leucine rich repeat, Ig-like and transmembrane domains 1
chr2_+_56183973 0.41 ENST00000407595.3
CCDC85A
coiled-coil domain containing 85A
chr10_-_87818153 0.41 ENST00000308448.11
ENST00000680024.1
ATAD1
ATPase family AAA domain containing 1
chr11_-_129024157 0.41 ENST00000392657.7
ARHGAP32
Rho GTPase activating protein 32
chr17_-_45133213 0.38 ENST00000538093.1
ENST00000590644.5
PLCD3
phospholipase C delta 3
chr6_-_83708713 0.38 ENST00000519825.5
ENST00000523484.6
SNAP91
synaptosome associated protein 91
chr19_-_55354540 0.38 ENST00000590900.5
COX6B2
cytochrome c oxidase subunit 6B2
chr12_-_13981957 0.38 ENST00000627535.2
ENST00000630791.2
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B
chr17_-_38343810 0.37 ENST00000621958.1
ENST00000616987.5
GPR179
G protein-coupled receptor 179
chr19_-_43619591 0.37 ENST00000598676.1
ENST00000300811.8
ZNF428
zinc finger protein 428
chr1_-_68449927 0.37 ENST00000262340.6
RPE65
retinoid isomerohydrolase RPE65
chr15_+_43593054 0.36 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr3_+_49021605 0.35 ENST00000451378.2
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chrX_-_33339525 0.35 ENST00000288447.9
DMD
dystrophin
chr12_-_13095664 0.35 ENST00000337630.10
ENST00000545699.1
GSG1
germ cell associated 1
chr3_-_32570771 0.34 ENST00000273130.9
ENST00000432458.6
ENST00000424991.1
DYNC1LI1
dynein cytoplasmic 1 light intermediate chain 1
chr14_+_23376786 0.34 ENST00000359320.7
CMTM5
CKLF like MARVEL transmembrane domain containing 5
chr3_-_50567711 0.34 ENST00000357203.8
C3orf18
chromosome 3 open reading frame 18
chr14_+_23376765 0.34 ENST00000649278.1
CMTM5
CKLF like MARVEL transmembrane domain containing 5
chr12_-_86256299 0.33 ENST00000552808.6
ENST00000547225.5
MGAT4C
MGAT4 family member C
chr15_-_34318761 0.33 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr4_+_153204410 0.33 ENST00000675838.1
ENST00000674967.1
ENST00000632856.2
ENST00000441616.6
ENST00000433687.2
ENST00000494872.6
ENST00000460908.2
ENST00000675780.1
ENST00000674976.1
ENST00000338700.10
ENST00000675293.1
ENST00000676172.1
ENST00000675673.1
ENST00000675492.1
ENST00000675425.1
ENST00000675384.1
ENST00000675063.1
ENST00000675340.1
ENST00000675835.1
ENST00000675054.1
ENST00000675710.1
ENST00000502281.3
ENSG00000288637.1
TRIM2
novel protein
tripartite motif containing 2
chr4_-_101347492 0.33 ENST00000394854.8
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr21_-_32727889 0.32 ENST00000630077.3
ENST00000674204.1
SYNJ1
synaptojanin 1
chr5_+_173889337 0.32 ENST00000520867.5
ENST00000334035.9
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_101846957 0.31 ENST00000338858.9
OLFM3
olfactomedin 3
chr5_+_138873990 0.31 ENST00000518381.5
CTNNA1
catenin alpha 1
chr1_+_171970115 0.31 ENST00000523513.1
DNM3
dynamin 3
chr11_-_30586866 0.31 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr22_-_38084093 0.31 ENST00000681075.1
SLC16A8
solute carrier family 16 member 8
chr12_+_14973020 0.31 ENST00000266395.3
PDE6H
phosphodiesterase 6H
chr15_-_34754989 0.31 ENST00000290374.5
GJD2
gap junction protein delta 2
chr16_+_81238682 0.30 ENST00000258168.7
ENST00000564552.1
BCO1
beta-carotene oxygenase 1
chr10_-_102418748 0.30 ENST00000020673.6
PSD
pleckstrin and Sec7 domain containing
chr8_-_113436883 0.30 ENST00000455883.2
ENST00000297405.10
CSMD3
CUB and Sushi multiple domains 3
chr7_+_136868622 0.30 ENST00000680005.1
ENST00000445907.6
CHRM2
cholinergic receptor muscarinic 2
chr10_-_59363176 0.30 ENST00000512919.5
FAM13C
family with sequence similarity 13 member C
chr10_-_125161019 0.30 ENST00000411419.6
CTBP2
C-terminal binding protein 2
chr9_+_34179005 0.30 ENST00000625521.2
ENST00000379186.8
ENST00000297661.9
ENST00000626262.2
UBAP1
ubiquitin associated protein 1
chr3_-_12987036 0.30 ENST00000618604.4
IQSEC1
IQ motif and Sec7 domain ArfGEF 1
chr11_-_130314686 0.29 ENST00000525842.5
ZBTB44
zinc finger and BTB domain containing 44
chr11_-_47176851 0.29 ENST00000629231.2
ENST00000526342.5
ENST00000528444.5
ENST00000530596.5
ENST00000525398.5
ENST00000524782.6
ENST00000527927.5
ENST00000525314.5
ARFGAP2
ADP ribosylation factor GTPase activating protein 2
chr3_-_197226351 0.29 ENST00000656428.1
DLG1
discs large MAGUK scaffold protein 1
chr3_-_98522514 0.29 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
CLDND1
claudin domain containing 1
chr16_+_76277568 0.28 ENST00000622250.4
CNTNAP4
contactin associated protein family member 4
chr9_-_35754256 0.28 ENST00000436428.3
MSMP
microseminoprotein, prostate associated
chr5_-_11588796 0.28 ENST00000513598.5
CTNND2
catenin delta 2
chrX_+_12137409 0.28 ENST00000672010.1
FRMPD4
FERM and PDZ domain containing 4
chr17_+_62458641 0.27 ENST00000582809.5
TLK2
tousled like kinase 2
chr1_+_164559378 0.27 ENST00000340699.7
PBX1
PBX homeobox 1
chr1_-_223845894 0.27 ENST00000391878.6
ENST00000343537.12
TP53BP2
tumor protein p53 binding protein 2
chr16_+_57976435 0.27 ENST00000290871.10
ENST00000441824.4
TEPP
testis, prostate and placenta expressed
chr2_-_229923163 0.26 ENST00000435716.5
TRIP12
thyroid hormone receptor interactor 12
chr12_-_49130113 0.26 ENST00000549870.5
TUBA1B
tubulin alpha 1b
chr11_+_67605488 0.26 ENST00000533876.1
ENST00000647561.1
ENSG00000255119.1
NDUFV1
novel transcript
NADH:ubiquinone oxidoreductase core subunit V1
chr6_+_12716554 0.26 ENST00000676159.1
PHACTR1
phosphatase and actin regulator 1
chr19_+_39498938 0.25 ENST00000356433.10
ENST00000596614.5
ENST00000205143.4
DLL3
delta like canonical Notch ligand 3
chr4_-_101347471 0.25 ENST00000323055.10
ENST00000512215.5
PPP3CA
protein phosphatase 3 catalytic subunit alpha
chr21_-_15002364 0.24 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr2_+_183078736 0.24 ENST00000354221.5
DUSP19
dual specificity phosphatase 19
chr3_+_49022077 0.24 ENST00000326925.11
NDUFAF3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr11_-_130314575 0.24 ENST00000397753.5
ZBTB44
zinc finger and BTB domain containing 44
chr17_-_57745292 0.23 ENST00000299415.3
CCDC182
coiled-coil domain containing 182
chr6_-_154247422 0.23 ENST00000519190.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr5_-_41510623 0.23 ENST00000328457.5
PLCXD3
phosphatidylinositol specific phospholipase C X domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.6 3.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.6 2.9 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.5 1.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.4 1.3 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.4 4.0 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.4 2.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.3 2.4 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 1.0 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.3 3.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.3 6.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 2.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 2.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 0.5 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 1.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 0.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 3.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 4.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 2.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.4 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 6.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.4 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.6 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:1904980 positive regulation of endosome organization(GO:1904980)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0016119 carotene metabolic process(GO:0016119)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.9 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.7 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.9 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 1.5 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.9 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.3 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.0 2.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 2.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 3.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.9 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 2.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:1900045 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.9 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 3.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957) response to chlorate(GO:0010157)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0055028 cortical microtubule(GO:0055028)
0.4 1.4 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.2 2.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.7 GO:0032127 dense core granule membrane(GO:0032127)
0.1 2.1 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.8 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 4.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.5 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 2.4 GO:0031143 pseudopodium(GO:0031143)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 2.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 7.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 3.6 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 7.2 GO:0042383 sarcolemma(GO:0042383)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 7.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0030132 clathrin coat of coated pit(GO:0030132)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 2.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.4 7.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 3.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 7.4 GO:0003680 AT DNA binding(GO:0003680)
0.3 1.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.3 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 2.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.8 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 4.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 2.6 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.3 GO:0042835 BRE binding(GO:0042835)
0.1 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.8 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 4.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.8 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.7 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.6 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 7.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 2.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 9.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 9.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 4.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 6.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 7.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 4.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 2.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 2.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 4.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions