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Illumina Body Map 2 (GSE30611)
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Results for PAX1_PAX9
Z-value: 0.71
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Transcription factors associated with PAX1_PAX9
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PAX1 | hg38_v1_chr20_+_21705651_21705673 | -0.45 | 9.2e-03 | Click! |
| PAX9 | hg38_v1_chr14_+_36657664_36657677 | 0.06 | 7.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of PAX1_PAX9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.0 | GO:0018277 | protein deamination(GO:0018277) |
| 1.3 | 4.0 | GO:0042660 | positive regulation of cell fate specification(GO:0042660) |
| 0.0 | 3.0 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.2 | 2.8 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 2.8 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 2.7 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.3 | 2.6 | GO:0010716 | negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343) |
| 0.0 | 2.2 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.0 | 2.0 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.0 | 1.5 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.0 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 3.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 3.0 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 2.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 2.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.5 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 1.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.0 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.1 | 4.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 3.0 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 2.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 2.6 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.4 | 2.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.0 | 2.0 | GO:0038187 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 1.5 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.0 | 1.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 1.4 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 2.8 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 2.8 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.6 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.2 | 4.0 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 2.8 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 2.6 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 2.3 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.1 | 1.4 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 1.4 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 1.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.6 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 0.3 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |