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Illumina Body Map 2 (GSE30611)

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Results for PAX4

Z-value: 1.48

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
ENSG00000106331.17 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg38_v1_chr7_-_127618137_127618145-0.125.0e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153375591 8.08 ENST00000368737.5
S100 calcium binding protein A12
chr1_+_26317950 7.06 ENST00000374213.3
CD52 molecule
chr4_-_83109843 6.73 ENST00000411416.6
placenta associated 8
chr1_+_101236860 5.50 ENST00000475821.2
sphingosine-1-phosphate receptor 1
chr6_+_31586124 5.49 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr1_+_101237009 4.73 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr6_+_31586269 4.57 ENST00000438075.7
leukocyte specific transcript 1
chr2_-_136118142 4.34 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr1_-_24964984 4.13 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr19_+_54593619 4.12 ENST00000251372.8
ENST00000453777.1
leukocyte immunoglobulin like receptor A1
chr2_-_136116165 4.09 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr6_+_32439866 4.05 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr11_-_59212869 3.80 ENST00000361050.4
macrophage expressed 1
chr22_-_17219424 3.72 ENST00000649540.1
ENST00000399837.8
ENST00000543038.1
adenosine deaminase 2
chr1_-_151059561 3.68 ENST00000357235.6
ENST00000540998.5
CDC42 small effector 1
chr19_-_54281145 3.62 ENST00000434421.5
ENST00000391749.4
leukocyte immunoglobulin like receptor B2
chr7_+_80638633 3.59 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr6_-_25042003 3.53 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr7_+_80638510 3.44 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr6_+_31586680 3.38 ENST00000339530.8
leukocyte specific transcript 1
chr7_+_80638662 3.37 ENST00000394788.7
CD36 molecule
chr17_+_45221854 3.33 ENST00000331495.8
formin like 1
chr5_+_119333151 3.29 ENST00000513374.1
TNF alpha induced protein 8
chr19_+_10848366 3.25 ENST00000397820.5
chromosome 19 open reading frame 38
chr12_-_44875647 3.24 ENST00000395487.6
neural EGFL like 2
chr6_+_31586835 3.23 ENST00000211921.11
leukocyte specific transcript 1
chr16_-_28610032 3.23 ENST00000567512.1
sulfotransferase family 1A member 1
chr19_-_54281082 3.20 ENST00000314446.10
leukocyte immunoglobulin like receptor B2
chr11_+_1853049 3.19 ENST00000311604.8
lymphocyte specific protein 1
chr16_-_28609992 3.16 ENST00000314752.11
sulfotransferase family 1A member 1
chr19_+_41549510 3.12 ENST00000407170.6
ENST00000601116.5
ENST00000595395.1
CEA cell adhesion molecule 21
novel transcript, sense intronic to CEACAM21
chr22_-_17219571 3.11 ENST00000610390.4
adenosine deaminase 2
chr12_-_44875980 3.09 ENST00000548826.5
neural EGFL like 2
chr16_-_28609976 3.08 ENST00000566189.5
sulfotransferase family 1A member 1
chr8_-_21913671 3.08 ENST00000523932.1
ENST00000276420.9
docking protein 2
chr20_-_53593829 3.05 ENST00000371471.7
zinc finger protein 217
chr2_-_86861871 2.99 ENST00000390655.12
ENST00000393759.6
ENST00000349455.7
ENST00000331469.6
ENST00000393761.6
ENST00000431506.3
CD8b molecule
chr22_-_31292445 2.90 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr5_+_147878703 2.85 ENST00000296694.5
secretoglobin family 3A member 2
chr17_+_45221993 2.78 ENST00000328118.7
formin like 1
chr22_+_22887780 2.69 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
immunoglobulin lambda like polypeptide 5
chr6_+_32637396 2.68 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr12_-_44875468 2.62 ENST00000553120.1
neural EGFL like 2
chr7_+_142587857 2.51 ENST00000617639.1
T cell receptor beta variable 14
chr6_+_32637419 2.46 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr19_+_54630410 2.45 ENST00000396327.7
ENST00000324602.12
leukocyte immunoglobulin like receptor B1
chr19_+_54630497 2.44 ENST00000396332.8
ENST00000427581.6
leukocyte immunoglobulin like receptor B1
chrY_+_2841594 2.39 ENST00000250784.13
ribosomal protein S4 Y-linked 1
chr14_-_49586325 2.39 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
ribosomal protein S29
chr8_-_21913661 2.37 ENST00000518197.1
docking protein 2
chrX_-_49264668 2.37 ENST00000455775.7
ENST00000652559.1
ENST00000376207.10
ENST00000557224.6
ENST00000684155.1
ENST00000376199.7
forkhead box P3
chrX_-_132489954 2.34 ENST00000370844.5
muscleblind like splicing regulator 3
chrX_-_132489842 2.20 ENST00000436215.5
muscleblind like splicing regulator 3
chr2_+_102355750 2.17 ENST00000233957.7
interleukin 18 receptor 1
chr6_+_20403679 2.07 ENST00000535432.2
E2F transcription factor 3
chr9_+_131228109 2.05 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
nucleoporin 214
chr9_-_20622479 2.03 ENST00000380338.9
MLLT3 super elongation complex subunit
chr1_+_21551260 2.00 ENST00000374832.5
alkaline phosphatase, biomineralization associated
chr19_-_55325316 1.93 ENST00000591570.5
ENST00000326652.9
transmembrane protein 150B
chr16_+_85555962 1.92 ENST00000635906.1
Gse1 coiled-coil protein
chr16_+_50696999 1.92 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr2_+_102355881 1.88 ENST00000409599.5
interleukin 18 receptor 1
chr6_+_15246054 1.88 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr6_+_31586859 1.84 ENST00000433492.5
leukocyte specific transcript 1
chr12_-_121039204 1.81 ENST00000620239.5
2'-5'-oligoadenylate synthetase like
chr12_-_121039236 1.80 ENST00000257570.9
2'-5'-oligoadenylate synthetase like
chr14_-_91244669 1.74 ENST00000650645.1
G protein-coupled receptor 68
chr12_-_121039156 1.67 ENST00000339275.10
2'-5'-oligoadenylate synthetase like
chr7_-_37449174 1.60 ENST00000445322.1
ENST00000448602.5
engulfment and cell motility 1
chr6_+_31615215 1.60 ENST00000337917.11
ENST00000376059.8
allograft inflammatory factor 1
chr11_+_72114840 1.59 ENST00000622388.4
folate receptor gamma
chrX_+_71910818 1.56 ENST00000633930.1
NHS like 2
chr6_+_132814566 1.56 ENST00000230050.4
ribosomal protein S12
chr15_-_40108861 1.54 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chr8_+_32548210 1.53 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr10_+_112375196 1.45 ENST00000393081.6
acyl-CoA synthetase long chain family member 5
chr18_-_63319987 1.43 ENST00000398117.1
BCL2 apoptosis regulator
chr7_+_26291941 1.42 ENST00000412416.5
sorting nexin 10
chr1_+_206440061 1.42 ENST00000604925.5
SLIT-ROBO Rho GTPase activating protein 2
chr9_-_20621835 1.38 ENST00000630269.2
MLLT3 super elongation complex subunit
chr11_-_65606959 1.38 ENST00000532507.5
mitogen-activated protein kinase kinase kinase 11
chr7_-_23470469 1.37 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr4_-_112285892 1.36 ENST00000361717.4
TRAF interacting protein with forkhead associated domain
chr17_-_79009778 1.31 ENST00000591773.5
ENST00000588611.5
ENST00000586916.6
ENST00000592033.5
ENST00000588075.5
ENST00000302345.6
ENST00000591811.1
calcium activated nucleotidase 1
chr7_+_26152188 1.29 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr16_+_69924984 1.28 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr6_-_32128191 1.28 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr15_-_60398733 1.28 ENST00000559818.6
annexin A2
chr22_-_39244969 1.25 ENST00000331163.11
platelet derived growth factor subunit B
chr12_-_108827384 1.24 ENST00000326470.9
slingshot protein phosphatase 1
chr11_-_124752247 1.24 ENST00000326621.10
V-set and immunoglobulin domain containing 2
chr1_-_85276467 1.23 ENST00000648566.1
BCL10 immune signaling adaptor
chr7_-_138002017 1.23 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr19_-_35900532 1.22 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKB inhibitor delta
chr3_-_142448028 1.20 ENST00000392981.7
5'-3' exoribonuclease 1
chr8_+_32548303 1.18 ENST00000650967.1
neuregulin 1
chr16_+_81779279 1.16 ENST00000564138.6
phospholipase C gamma 2
chr18_-_55588146 1.16 ENST00000627784.2
transcription factor 4
chr3_-_142448060 1.16 ENST00000264951.8
5'-3' exoribonuclease 1
chr16_-_28597042 1.13 ENST00000533150.5
ENST00000335715.9
sulfotransferase family 1A member 2
chr1_+_12063357 1.12 ENST00000417814.3
TNF receptor superfamily member 8
chr18_-_63319729 1.12 ENST00000333681.5
BCL2 apoptosis regulator
chr18_-_55422492 1.09 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr17_-_79009731 1.08 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
calcium activated nucleotidase 1
chr11_-_62601223 1.06 ENST00000527204.5
metastasis associated 1 family member 2
chr18_-_55588184 1.03 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr4_-_140152969 1.02 ENST00000502696.1
mastermind like transcriptional coactivator 3
chr1_+_12063285 1.00 ENST00000263932.7
TNF receptor superfamily member 8
chr11_+_20363685 1.00 ENST00000530266.5
ENST00000451739.7
ENST00000421577.6
ENST00000443524.6
ENST00000419348.6
HIV-1 Tat interactive protein 2
chr4_+_47485268 0.98 ENST00000273859.8
ENST00000504445.1
ATPase phospholipid transporting 10D (putative)
chr2_-_229923163 0.97 ENST00000435716.5
thyroid hormone receptor interactor 12
chr16_-_17470953 0.96 ENST00000261381.7
xylosyltransferase 1
chr6_-_32838727 0.96 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chrX_-_132413567 0.95 ENST00000538204.5
ENST00000370849.7
muscleblind like splicing regulator 3
chr7_-_138001794 0.92 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr2_+_202073282 0.92 ENST00000459709.5
KIAA2012
chr3_-_197749688 0.91 ENST00000273582.9
rubicon autophagy regulator
chr18_+_32091849 0.90 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr2_+_106487349 0.89 ENST00000643224.2
ENST00000416057.2
CD8b2 molecule
chr12_+_64497968 0.89 ENST00000676593.1
ENST00000677093.1
TANK binding kinase 1
novel transcript
chr22_-_37109703 0.89 ENST00000406856.7
ENST00000676104.1
transmembrane serine protease 6
chr8_-_115668609 0.88 ENST00000220888.9
transcriptional repressor GATA binding 1
chr1_-_231241090 0.86 ENST00000451322.1
chromosome 1 open reading frame 131
chr21_-_32279012 0.85 ENST00000290130.4
MIS18 kinetochore protein A
chr18_-_55588535 0.83 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr16_-_84239750 0.82 ENST00000568181.1
potassium voltage-gated channel modifier subfamily G member 4
chr19_+_14433384 0.82 ENST00000586557.5
ENST00000590097.5
protein kinase N1
chr2_-_207624551 0.81 ENST00000272839.7
ENST00000426075.5
methyltransferase like 21A
chr10_+_113126670 0.80 ENST00000369389.6
transcription factor 7 like 2
chr3_-_9880250 0.79 ENST00000423850.5
ENST00000336832.7
ENST00000675828.1
ENST00000618572.4
ENST00000455015.6
cell death inducing DFFA like effector c
chr8_+_32548267 0.79 ENST00000356819.7
neuregulin 1
chr18_-_55422306 0.79 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr11_-_124752187 0.78 ENST00000403470.1
V-set and immunoglobulin domain containing 2
chr3_-_142448004 0.78 ENST00000463916.5
5'-3' exoribonuclease 1
chr8_+_11809135 0.77 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr18_+_3448456 0.75 ENST00000549780.5
TGFB induced factor homeobox 1
chr11_+_12094008 0.74 ENST00000532179.5
ENST00000526065.1
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr15_-_40108704 0.74 ENST00000560430.1
Bcl2 modifying factor
chrX_-_132413597 0.71 ENST00000394311.6
muscleblind like splicing regulator 3
chr2_-_24328113 0.70 ENST00000622089.4
intersectin 2
chr20_-_46364385 0.68 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
solute carrier family 35 member C2
chr5_+_163503075 0.68 ENST00000280969.9
methionine adenosyltransferase 2B
chr7_-_22220226 0.67 ENST00000420196.5
Rap guanine nucleotide exchange factor 5
chr1_-_231241121 0.66 ENST00000318906.6
ENST00000366649.7
ENST00000366651.7
chromosome 1 open reading frame 131
chr2_+_203014721 0.66 ENST00000683091.1
neurobeachin like 1
chr3_+_119579676 0.66 ENST00000357003.7
ADP-ribosylarginine hydrolase
chr8_-_115668896 0.65 ENST00000519674.1
transcriptional repressor GATA binding 1
chr1_-_204494752 0.64 ENST00000684373.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr2_+_202073249 0.63 ENST00000498697.3
KIAA2012
chr5_-_55692620 0.63 ENST00000503817.5
ENST00000512595.5
solute carrier family 38 member 9
chr21_+_42514523 0.63 ENST00000398343.2
solute carrier family 37 member 1
chr18_+_75210755 0.62 ENST00000322038.5
teashirt zinc finger homeobox 1
chr11_-_64777751 0.62 ENST00000433274.6
ENST00000432725.1
splicing factor 1
chr18_+_75210789 0.61 ENST00000580243.3
teashirt zinc finger homeobox 1
chr1_-_228406761 0.61 ENST00000366699.3
ENST00000284551.11
tripartite motif containing 11
chr11_+_46719193 0.60 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
coagulation factor II, thrombin
chr3_-_71583713 0.60 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr14_+_103928432 0.60 ENST00000409874.9
tudor domain containing 9
chr11_+_20363780 0.60 ENST00000532505.1
HIV-1 Tat interactive protein 2
chrX_-_102155790 0.60 ENST00000543160.5
ENST00000333643.4
brain expressed X-linked 5
chr7_+_66921217 0.59 ENST00000341567.8
ENST00000607045.5
transmembrane protein 248
chr1_-_152089062 0.58 ENST00000368806.2
trichohyalin like 1
chr5_+_144205250 0.57 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr17_+_75093287 0.57 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr18_+_32190033 0.57 ENST00000269202.11
meprin A subunit beta
chr17_+_16381083 0.56 ENST00000535788.1
ENST00000302182.8
ubiquitin B
chr15_-_34210073 0.56 ENST00000559515.1
ENST00000560108.5
ENST00000256544.8
ENST00000559462.1
katanin regulatory subunit B1 like 1
chrX_+_16946650 0.56 ENST00000357277.8
RALBP1 associated Eps domain containing 2
chr12_+_861124 0.55 ENST00000676347.1
WNK lysine deficient protein kinase 1
chr9_-_120914549 0.55 ENST00000546084.5
TNF receptor associated factor 1
chr3_+_69084973 0.55 ENST00000478935.1
ADP ribosylation factor like GTPase 6 interacting protein 5
chr8_+_41490396 0.53 ENST00000518270.5
ENST00000520817.5
golgin A7
chr4_+_94207845 0.53 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_-_120926752 0.52 ENST00000373887.8
TNF receptor associated factor 1
chr18_+_32190015 0.51 ENST00000581447.1
meprin A subunit beta
chr10_-_114768061 0.51 ENST00000651092.1
actin binding LIM protein 1
chr18_-_5396265 0.51 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr8_-_673547 0.50 ENST00000522893.1
glutamate rich 1
chr12_+_116559381 0.49 ENST00000556529.4
microtubule associated protein 1 light chain 3 beta 2
chr4_+_108650644 0.49 ENST00000512478.2
oligosaccharyltransferase complex non-catalytic subunit
chr2_-_85612023 0.48 ENST00000409734.3
ENST00000306336.6
chromosome 2 open reading frame 68
chr4_-_175812746 0.48 ENST00000393658.6
glycoprotein M6A
chr12_-_56752311 0.48 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr16_+_53054973 0.47 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr18_+_31447732 0.46 ENST00000257189.5
desmoglein 3
chr5_-_175968280 0.45 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THO complex 3
chr16_-_84240012 0.43 ENST00000308251.6
potassium voltage-gated channel modifier subfamily G member 4
chr15_+_80152978 0.42 ENST00000561421.6
ENST00000684363.1
fumarylacetoacetate hydrolase
chr10_-_68232108 0.41 ENST00000373673.5
atonal bHLH transcription factor 7
chr12_-_16610037 0.41 ENST00000540590.1
LIM domain only 3
chr11_-_62707331 0.40 ENST00000533982.1
BSCL2 lipid droplet biogenesis associated, seipin
chr10_+_72893572 0.39 ENST00000622652.1
oncoprotein induced transcript 3
chr14_-_68793055 0.38 ENST00000439696.3
ZFP36 ring finger protein like 1
chr1_-_151346806 0.37 ENST00000392746.7
regulatory factor X5
chr18_-_55422262 0.37 ENST00000629343.2
transcription factor 4
chr19_+_38289138 0.37 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
serine peptidase inhibitor, Kunitz type 2
novel protein
chr2_-_179264757 0.36 ENST00000428443.8
SEC14 and spectrin domain containing 1
chr5_-_133968578 0.36 ENST00000231512.5
chromosome 5 open reading frame 15
chr2_-_207624983 0.36 ENST00000448007.6
ENST00000432416.5
ENST00000411432.5
ENST00000458426.5
ENST00000406927.6
ENST00000425132.5
methyltransferase like 21A
chr3_-_128153782 0.36 ENST00000464873.5
RuvB like AAA ATPase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.5 11.7 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.4 4.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.0 6.8 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.8 8.4 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.8 10.4 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.8 2.4 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465)
0.7 2.1 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.7 2.0 GO:0071529 cementum mineralization(GO:0071529)
0.7 5.3 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.6 3.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.6 3.5 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.5 2.6 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.5 1.9 GO:0032499 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 8.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 1.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.4 10.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.4 1.2 GO:0002316 follicular B cell differentiation(GO:0002316)
0.3 3.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.0 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.3 1.3 GO:0044035 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 1.2 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.3 1.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.3 6.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.7 GO:0019417 sulfur oxidation(GO:0019417)
0.2 5.8 GO:0051014 actin filament severing(GO:0051014)
0.2 2.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 3.5 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.2 1.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 1.2 GO:0060023 soft palate development(GO:0060023)
0.2 1.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.7 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 3.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 8.3 GO:0050832 defense response to fungus(GO:0050832)
0.2 7.1 GO:0045730 respiratory burst(GO:0045730)
0.2 18.5 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.2 1.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.2 0.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.2 6.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 4.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.8 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.0 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.0 GO:1902527 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.1 1.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.6 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.6 GO:0015884 folic acid transport(GO:0015884)
0.1 1.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.3 GO:0090135 actin filament branching(GO:0090135) protein localization to cell leading edge(GO:1902463)
0.1 0.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 4.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 2.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.2 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.3 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 10.4 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.3 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.7 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 3.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 2.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.9 GO:0097264 self proteolysis(GO:0097264)
0.0 0.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 2.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 1.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 4.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 3.4 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 2.7 GO:0006968 cellular defense response(GO:0006968)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 6.1 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 2.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0021554 optic nerve development(GO:0021554)
0.0 2.1 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 2.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 3.5 GO:0060171 stereocilium membrane(GO:0060171)
0.3 1.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 0.7 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.2 GO:0032449 CBM complex(GO:0032449)
0.2 10.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 3.2 GO:0032059 bleb(GO:0032059)
0.1 1.0 GO:0042825 TAP complex(GO:0042825)
0.1 1.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.6 GO:0071547 piP-body(GO:0071547)
0.1 2.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 2.6 GO:0046930 pore complex(GO:0046930)
0.1 3.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 13.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.4 GO:0044327 dendritic spine head(GO:0044327)
0.1 6.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 3.8 GO:0030673 axolemma(GO:0030673)
0.1 6.8 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 1.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 12.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 7.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.1 GO:0034774 secretory granule lumen(GO:0034774)
0.0 8.8 GO:0005770 late endosome(GO:0005770)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 3.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0097386 glial cell projection(GO:0097386)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 4.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 16.7 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 4.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.3 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 10.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.5 11.7 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
1.4 4.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.9 10.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 8.4 GO:0032027 myosin light chain binding(GO:0032027)
0.6 6.8 GO:0031685 adenosine receptor binding(GO:0031685)
0.6 2.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.5 9.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.5 10.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.5 3.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 8.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 5.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.3 1.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 2.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.3 6.1 GO:0005522 profilin binding(GO:0005522)
0.2 1.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.0 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.2 5.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 5.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.6 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 2.4 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.7 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 3.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 0.8 GO:0003896 DNA primase activity(GO:0003896)
0.2 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.7 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 1.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.8 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.6 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 2.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 3.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 3.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.7 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.1 1.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 3.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.6 GO:0005542 folic acid binding(GO:0005542)
0.1 3.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 1.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 3.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 1.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.9 GO:0045295 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 6.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 4.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 4.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 19.9 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 3.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 8.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 5.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 2.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 6.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 4.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 11.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.4 10.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 8.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 18.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 4.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 11.4 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 3.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 6.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.9 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 5.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 5.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 9.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor