Illumina Body Map 2 (GSE30611)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
PAX5 | hg38_v1_chr9_-_37034261_37034273 | 0.82 | 1.2e-08 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 199.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.4 | 86.2 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.1 | 41.4 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
0.1 | 39.7 | GO:0002250 | adaptive immune response(GO:0002250) |
0.2 | 17.4 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
0.1 | 17.0 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.3 | 16.8 | GO:0071800 | podosome assembly(GO:0071800) |
0.2 | 14.9 | GO:0006968 | cellular defense response(GO:0006968) |
0.1 | 12.7 | GO:0031295 | T cell costimulation(GO:0031295) |
0.1 | 10.4 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 62.9 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.1 | 52.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 40.5 | GO:0005615 | extracellular space(GO:0005615) |
0.1 | 26.0 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 22.7 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.2 | 21.5 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
0.0 | 21.1 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.1 | 20.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.5 | 18.8 | GO:0001891 | phagocytic cup(GO:0001891) |
0.3 | 17.3 | GO:0001772 | immunological synapse(GO:0001772) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 224.5 | GO:0003823 | antigen binding(GO:0003823) |
1.2 | 84.9 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 22.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.2 | 19.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.2 | 12.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 11.6 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.5 | 11.0 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.2 | 10.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.6 | 9.1 | GO:0019864 | IgG binding(GO:0019864) |
0.0 | 9.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 49.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
0.2 | 28.1 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.4 | 17.9 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
0.4 | 15.7 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 15.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.2 | 13.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
0.3 | 11.0 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
0.2 | 10.5 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
0.2 | 10.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.3 | 9.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 41.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.3 | 24.5 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.1 | 18.2 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.3 | 17.9 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.2 | 16.5 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.7 | 15.8 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.4 | 10.8 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.2 | 10.5 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 10.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.3 | 9.7 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |