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Illumina Body Map 2 (GSE30611)

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Results for POU2F1

Z-value: 1.52

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Transcription factors associated with POU2F1

Gene Symbol Gene ID Gene Info
ENSG00000143190.23 POU class 2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F1hg38_v1_chr1_+_167329148_1673291750.096.3e-01Click!

Activity profile of POU2F1 motif

Sorted Z-values of POU2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_89245596 8.54 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr22_+_22686724 7.97 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr14_-_105987068 7.80 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr17_+_36064265 6.81 ENST00000616054.2
C-C motif chemokine ligand 18
chr14_-_106185387 6.37 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr2_-_88992903 5.94 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_-_106277039 5.92 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr14_-_106715166 5.85 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr2_+_89936859 5.73 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr14_-_106579223 5.14 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr11_-_5227063 4.91 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr14_-_106622837 4.56 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr2_-_89222461 4.47 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr15_-_21718245 4.40 ENST00000630556.1
novel gene identicle to IGHV1OR15-1
chr2_-_89330429 4.37 ENST00000620613.1
immunoglobulin kappa variable 2-40
chr14_-_106012390 3.98 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr14_-_106005574 3.93 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr2_+_88897230 3.80 ENST00000390244.2
immunoglobulin kappa variable 5-2
chr12_-_110920568 3.78 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr2_+_90021567 3.50 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr7_+_80638510 3.44 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr1_-_160711803 3.30 ENST00000368045.3
ENST00000368046.8
ENST00000613788.1
CD48 molecule
chr1_+_158831323 3.15 ENST00000368141.5
myeloid cell nuclear differentiation antigen
chr13_-_46142834 3.14 ENST00000674665.1
lymphocyte cytosolic protein 1
chr22_+_22668286 3.14 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr8_-_7018295 3.12 ENST00000327857.7
defensin alpha 3
chrX_+_15500800 3.07 ENST00000348343.11
BMX non-receptor tyrosine kinase
chr14_-_106025628 3.03 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr8_-_85378105 2.90 ENST00000521846.5
ENST00000523022.6
ENST00000524324.5
ENST00000519991.5
ENST00000520663.5
ENST00000517590.5
ENST00000522579.5
ENST00000522814.5
ENST00000522662.5
ENST00000523858.5
ENST00000519129.5
carbonic anhydrase 1
chr8_-_6980092 2.80 ENST00000382692.3
defensin alpha 1
chr8_-_6999198 2.79 ENST00000382689.8
defensin alpha 1B
chr3_+_157436842 2.78 ENST00000295927.4
pentraxin 3
chr11_-_128587551 2.64 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr1_+_158931539 2.57 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
pyrin and HIN domain family member 1
chr22_+_22747383 2.51 ENST00000390311.3
immunoglobulin lambda variable 3-16
chr19_+_14583076 2.50 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr4_+_40192949 2.46 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chr1_-_89270751 2.40 ENST00000370459.7
guanylate binding protein 5
chr12_-_102480552 2.19 ENST00000337514.11
ENST00000307046.8
insulin like growth factor 1
chr11_-_107858777 2.18 ENST00000525815.6
solute carrier family 35 member F2
chr1_-_24964984 2.13 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr4_-_99321362 2.13 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_-_58575846 2.11 ENST00000395074.7
leupaxin
chr14_+_21868822 2.09 ENST00000390436.2
T cell receptor alpha variable 13-1
chr17_+_40015428 1.99 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr22_-_37175049 1.99 ENST00000453962.5
ENST00000429622.5
ENST00000445595.1
interleukin 2 receptor subunit beta
chr4_+_67558719 1.98 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr2_+_36696790 1.98 ENST00000497382.5
ENST00000404084.5
ENST00000379241.7
ENST00000401530.5
vitrin
chr2_+_203706475 1.95 ENST00000374481.7
ENST00000458610.6
CD28 molecule
chr12_+_59664677 1.92 ENST00000548610.5
solute carrier family 16 member 7
chr21_-_10649835 1.92 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr6_+_127577168 1.78 ENST00000329722.8
chromosome 6 open reading frame 58
chr5_+_119333151 1.75 ENST00000513374.1
TNF alpha induced protein 8
chr14_-_106875069 1.74 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr2_+_203706614 1.74 ENST00000324106.9
CD28 molecule
chr16_+_33827140 1.73 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr9_+_110125491 1.73 ENST00000259318.7
PALM2 and AKAP2 fusion
chr18_+_3252208 1.73 ENST00000578562.6
myosin light chain 12A
chr14_-_20802836 1.72 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr14_-_20802402 1.70 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr12_-_102480604 1.68 ENST00000392905.7
insulin like growth factor 1
chr8_+_30387064 1.66 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr1_+_103750406 1.63 ENST00000370079.3
amylase alpha 1C
chr12_-_7444139 1.58 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr4_-_143905529 1.58 ENST00000358615.9
ENST00000437468.2
glycophorin E (MNS blood group)
chr13_-_37598750 1.58 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr12_-_102480638 1.52 ENST00000392904.5
insulin like growth factor 1
chr4_+_119135825 1.39 ENST00000307128.6
myozenin 2
chr12_-_7092484 1.38 ENST00000541042.5
ENST00000540242.2
complement C1r
chr3_+_101827982 1.35 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr12_-_7092422 1.33 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr11_-_107858561 1.29 ENST00000375682.8
solute carrier family 35 member F2
chr2_+_36696686 1.29 ENST00000379242.7
ENST00000389975.7
vitrin
chr2_-_189225175 1.29 ENST00000649966.1
collagen type V alpha 2 chain
chr8_+_103298433 1.24 ENST00000522566.5
frizzled class receptor 6
chr6_-_46954922 1.22 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr4_+_73436198 1.21 ENST00000395792.7
alpha fetoprotein
chr2_+_167187283 1.20 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr14_+_21621801 1.15 ENST00000542354.1
T cell receptor alpha variable 1-1
chr4_+_73436244 1.15 ENST00000226359.2
alpha fetoprotein
chr4_+_74365136 1.15 ENST00000244869.3
epiregulin
chr17_-_43833137 1.13 ENST00000398389.9
membrane palmitoylated protein 3
chr8_-_92095627 1.13 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr1_+_198639162 1.10 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr15_-_51243011 1.09 ENST00000405913.7
ENST00000559878.5
cytochrome P450 family 19 subfamily A member 1
chr7_-_13986498 1.08 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr15_-_55249029 1.06 ENST00000566877.5
RAB27A, member RAS oncogene family
chr3_+_12308729 1.02 ENST00000683749.1
peroxisome proliferator activated receptor gamma
chr2_+_36696758 0.99 ENST00000457137.6
vitrin
chr8_-_116755784 0.97 ENST00000518949.5
ENST00000522453.1
ENST00000518995.5
ENST00000521861.6
ENST00000611080.1
eukaryotic translation initiation factor 3 subunit H
chr17_-_68955332 0.96 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr6_-_26216673 0.95 ENST00000541790.3
H2B clustered histone 8
chr19_+_39412650 0.95 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr7_-_13986439 0.94 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr6_+_135181361 0.89 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chrX_+_155026835 0.88 ENST00000369498.8
FUN14 domain containing 2
chr9_-_14300231 0.88 ENST00000636735.1
nuclear factor I B
chr11_-_8871353 0.86 ENST00000526155.5
ENST00000524757.5
ENST00000527392.5
ENST00000534665.5
ENST00000525169.5
DENN domain containing 2B
chr12_-_7092529 0.86 ENST00000540610.5
complement C1r
chr16_+_14200330 0.83 ENST00000573051.1
myocardin related transcription factor B
chr2_+_172427331 0.83 ENST00000412899.5
ENST00000409532.5
integrin subunit alpha 6
chr17_-_7484205 0.82 ENST00000311403.4
zinc finger and BTB domain containing 4
chr4_+_40192989 0.81 ENST00000508513.5
ras homolog family member H
chr1_-_169734064 0.75 ENST00000333360.12
selectin E
chr4_-_106368772 0.75 ENST00000638719.4
GIMAP family P-loop NTPase domain containing 1
chr3_-_111595339 0.74 ENST00000317012.5
zinc finger BED-type containing 2
chr15_+_85582889 0.74 ENST00000560340.5
A-kinase anchoring protein 13
chr20_+_59123381 0.72 ENST00000637017.1
zinc finger protein 831
chr11_-_101907934 0.72 ENST00000534527.1
angiopoietin like 5
chr7_+_142535763 0.71 ENST00000614171.1
T cell receptor beta variable 13
chr2_+_98245427 0.70 ENST00000614454.1
von Willebrand factor A domain containing 3B
chr4_-_144019287 0.69 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr11_-_101129806 0.69 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr2_+_102418642 0.67 ENST00000264260.6
interleukin 18 receptor accessory protein
chr4_+_69931066 0.66 ENST00000246891.9
casein alpha s1
chr11_-_59212869 0.65 ENST00000361050.4
macrophage expressed 1
chr6_-_123636997 0.65 ENST00000546248.5
triadin
chr18_-_63644250 0.65 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr12_-_71663791 0.65 ENST00000548100.1
zinc finger C3H1-type containing
chr8_-_92095598 0.64 ENST00000520724.5
ENST00000518844.5
RUNX1 partner transcriptional co-repressor 1
chr10_+_78033760 0.63 ENST00000435275.5
ENST00000613865.5
ENST00000645440.1
ENST00000464716.6
ENST00000360830.9
ENST00000372360.9
ENST00000440692.6
ribosomal protein S24
chr18_+_63476927 0.62 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr8_-_48921419 0.62 ENST00000020945.4
snail family transcriptional repressor 2
chr1_+_103749898 0.61 ENST00000622339.5
amylase alpha 1C
chr4_+_69995958 0.61 ENST00000381060.2
ENST00000246895.9
statherin
chr3_-_71306012 0.58 ENST00000649431.1
ENST00000610810.5
forkhead box P1
chr2_+_70978380 0.56 ENST00000272421.10
ENST00000441349.5
ENST00000457410.5
ankyrin repeat domain 53
chr6_+_116511626 0.56 ENST00000368599.4
calcium homeostasis modulator family member 5
chr3_-_108058361 0.55 ENST00000398258.7
CD47 molecule
chr14_-_91780688 0.54 ENST00000556661.5
ENST00000553676.1
ENST00000554560.5
cation channel sperm associated auxiliary subunit beta
chr9_-_35079923 0.54 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr1_-_226739271 0.53 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr2_+_71453538 0.52 ENST00000258104.8
dysferlin
chr17_+_77185210 0.50 ENST00000431431.6
SEC14 like lipid binding 1
chr10_+_124942123 0.49 ENST00000359653.4
zinc finger RANBP2-type containing 1
chr1_-_48400826 0.49 ENST00000371841.1
spermatogenesis associated 6
chr20_+_62796432 0.48 ENST00000370487.5
MRG domain binding protein
chr9_-_83267230 0.45 ENST00000328788.5
FERM domain containing 3
chr6_+_135181268 0.45 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr19_-_42594957 0.44 ENST00000599005.1
CEA cell adhesion molecule 8
chr6_-_123636923 0.44 ENST00000334268.9
triadin
chr2_+_168802610 0.43 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr3_+_136957948 0.41 ENST00000329582.9
interleukin 20 receptor subunit beta
chr13_+_108218366 0.41 ENST00000375898.4
abhydrolase domain containing 13
chr2_-_112836702 0.41 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr4_-_151226427 0.41 ENST00000304527.8
ENST00000409598.8
SH3 domain containing 19
chr2_+_161231078 0.41 ENST00000439442.1
TRAF family member associated NFKB activator
chr6_-_169250825 0.40 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr9_-_137302264 0.40 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr3_-_121660892 0.40 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr19_-_14090963 0.39 ENST00000269724.5
sterile alpha motif domain containing 1
chr9_+_113505256 0.39 ENST00000374136.5
regulator of G protein signaling 3
chr11_-_8871385 0.39 ENST00000527516.5
ENST00000533471.5
DENN domain containing 2B
chr15_+_48331011 0.35 ENST00000559935.5
ENST00000559416.5
deoxyuridine triphosphatase
chr6_-_123636906 0.35 ENST00000628709.2
triadin
chr2_+_70978624 0.34 ENST00000360589.4
ankyrin repeat domain 53
chr10_-_114526897 0.34 ENST00000428430.1
ENST00000392952.7
actin binding LIM protein 1
chr12_-_29444236 0.34 ENST00000537054.1
ovochymase 1
chr1_+_161766347 0.34 ENST00000679833.1
activating transcription factor 6
chr12_-_118359105 0.34 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr11_-_101129706 0.34 ENST00000534013.5
progesterone receptor
chr6_-_123636979 0.33 ENST00000662930.1
triadin
chr3_-_165078480 0.33 ENST00000264382.8
sucrase-isomaltase
chr1_+_161766309 0.32 ENST00000679853.1
ENST00000681492.1
ENST00000679886.1
ENST00000367942.4
ENST00000680462.1
ENST00000680633.1
ENST00000681912.1
activating transcription factor 6
chr19_+_17747698 0.32 ENST00000594202.5
ENST00000252771.11
FCH and mu domain containing endocytic adaptor 1
chr3_+_2511597 0.31 ENST00000434053.5
contactin 4
chr17_+_40015361 0.31 ENST00000583218.5
colony stimulating factor 3
chr2_+_168802563 0.31 ENST00000445023.6
nitric oxide synthase trafficking
chr2_-_206718396 0.31 ENST00000452335.2
dystrotelin
chr3_-_149576203 0.30 ENST00000472417.1
WW domain containing transcription regulator 1
chr4_-_915733 0.30 ENST00000511229.5
cyclin G associated kinase
chr11_+_94567362 0.30 ENST00000299001.11
piwi like RNA-mediated gene silencing 4
chr19_+_54816468 0.29 ENST00000391728.8
ENST00000326542.11
ENST00000358178.4
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
chr2_-_68319887 0.29 ENST00000409862.1
ENST00000263655.4
cannabinoid receptor interacting protein 1
chr6_-_123636966 0.29 ENST00000542443.5
triadin
chr6_-_135103048 0.28 ENST00000529882.5
HBS1 like translational GTPase
chr12_+_112906949 0.28 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr8_-_92095468 0.28 ENST00000520583.5
ENST00000519061.5
RUNX1 partner transcriptional co-repressor 1
chr6_+_167291309 0.27 ENST00000230256.8
unc-93 homolog A
chr2_-_144517506 0.27 ENST00000431672.4
ENST00000558170.6
zinc finger E-box binding homeobox 2
chr10_+_116427839 0.27 ENST00000369230.4
pancreatic lipase related protein 3
chr8_-_92095498 0.26 ENST00000520974.5
RUNX1 partner transcriptional co-repressor 1
chr20_+_37744630 0.26 ENST00000373473.5
catenin beta like 1
chr1_+_25272527 0.25 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr3_-_146222426 0.24 ENST00000481701.5
phospholipid scramblase 4
chr6_+_85449584 0.24 ENST00000369651.7
5'-nucleotidase ecto
chr1_+_161766282 0.24 ENST00000680688.1
activating transcription factor 6
chr20_+_9166322 0.24 ENST00000416836.5
phospholipase C beta 4
chr3_-_167474026 0.22 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr6_+_135181323 0.21 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr11_+_74748831 0.21 ENST00000299563.5
ring finger protein 169
chr7_+_48171451 0.21 ENST00000435803.6
ATP binding cassette subfamily A member 13
chr8_+_18210101 0.20 ENST00000307719.9
ENST00000518029.5
N-acetyltransferase 1
chr9_+_92964272 0.20 ENST00000468206.6
FYVE, RhoGEF and PH domain containing 3
chr12_-_50222694 0.19 ENST00000552783.5
LIM domain and actin binding 1
chr7_+_57450171 0.19 ENST00000420713.2
zinc finger protein 716
chr3_+_196739839 0.19 ENST00000327134.7
p21 (RAC1) activated kinase 2
chr12_-_106086809 0.19 ENST00000548902.1
NUAK family kinase 1
chr1_-_68497030 0.19 ENST00000456315.7
ENST00000525124.1
ENST00000370966.9
DEP domain containing 1
chr6_+_106541111 0.18 ENST00000457437.1
crystallin beta-gamma domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0030185 nitric oxide transport(GO:0030185)
1.1 5.4 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.9 2.8 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.9 2.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.7 2.0 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.5 1.6 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.5 84.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.4 2.1 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.4 1.1 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.3 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.6 GO:1990523 bone regeneration(GO:1990523)
0.3 1.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 5.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.3 3.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.3 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 3.7 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.2 2.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 2.6 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 2.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 1.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 3.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 0.6 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.4 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 1.9 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 3.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 2.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 1.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 4.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0001808 regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.1 3.1 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.1 3.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.0 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 2.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 1.2 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.1 0.4 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.9 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 6.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.5 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.9 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 1.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.3 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 2.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0046541 saliva secretion(GO:0046541)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 3.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.0 0.5 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 18.5 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.1 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 1.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.9 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 1.2 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 1.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 1.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 33.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 5.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.3 0.8 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.2 3.8 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 2.1 GO:0033018 junctional membrane complex(GO:0030314) sarcoplasmic reticulum lumen(GO:0033018)
0.1 4.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 18.0 GO:0072562 blood microparticle(GO:0072562)
0.1 1.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 6.6 GO:0001772 immunological synapse(GO:0001772)
0.1 3.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.2 GO:0002102 podosome(GO:0002102)
0.1 1.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 8.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0071547 piP-body(GO:0071547)
0.0 0.5 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 2.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 4.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.7 GO:0016459 myosin complex(GO:0016459)
0.0 2.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.9 GO:0030492 hemoglobin binding(GO:0030492)
0.6 3.4 GO:0004522 ribonuclease A activity(GO:0004522)
0.5 1.9 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.5 33.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 2.0 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.4 2.5 GO:0042806 fucose binding(GO:0042806)
0.3 66.6 GO:0003823 antigen binding(GO:0003823)
0.3 2.9 GO:0004064 arylesterase activity(GO:0004064)
0.3 3.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 2.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 2.8 GO:0046790 virion binding(GO:0046790)
0.2 0.6 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 1.4 GO:0051373 FATZ binding(GO:0051373)
0.2 3.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 6.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 1.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 3.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 4.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.0 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 3.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 2.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 1.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 2.1 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 3.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 4.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 5.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.9 REACTOME DEFENSINS Genes involved in Defensins
0.2 2.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 3.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 5.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism