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Illumina Body Map 2 (GSE30611)

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Results for POU3F3_POU3F4

Z-value: 1.58

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
ENSG00000198914.5 POU class 3 homeobox 3
ENSG00000196767.9 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F3hg38_v1_chr2_+_104854104_1048541240.494.5e-03Click!
POU3F4hg38_v1_chrX_+_83508284_835083090.096.1e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_167234426 7.22 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_-_46491956 7.16 ENST00000306764.11
regulator of calcineurin 2
chr15_-_45378519 6.64 ENST00000558163.1
ENST00000396659.8
ENST00000675323.1
ENST00000558336.5
glycine amidinotransferase
chr17_+_3475959 6.56 ENST00000263080.3
aspartoacylase
chr4_-_167234579 5.85 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr3_-_58627596 5.53 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr3_+_159069252 5.53 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr12_+_40827992 5.06 ENST00000547849.5
contactin 1
chr14_-_20802836 4.97 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr19_+_735026 4.85 ENST00000592155.5
ENST00000590161.2
paralemmin
chr9_+_74615582 4.77 ENST00000396204.2
RAR related orphan receptor B
chr14_-_20802402 4.71 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr11_-_35420017 4.59 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr5_-_11589019 4.46 ENST00000511377.5
catenin delta 2
chr8_-_144605699 4.09 ENST00000377307.6
ENST00000276826.5
Rho GTPase activating protein 39
chr3_+_35681352 3.96 ENST00000436702.5
ENST00000438071.1
cAMP regulated phosphoprotein 21
chr2_-_182522556 3.89 ENST00000435564.5
phosphodiesterase 1A
chr8_-_90082871 3.74 ENST00000265431.7
calbindin 1
chr3_+_35680994 3.63 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr5_+_126423176 3.62 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_141121793 3.57 ENST00000194152.4
protocadherin beta 4
chr7_-_14841267 3.54 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr5_-_79514127 3.48 ENST00000334082.11
homer scaffold protein 1
chr5_-_161546708 3.43 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr17_-_68955332 3.43 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr5_-_11588842 3.31 ENST00000503622.5
catenin delta 2
chr4_-_21948733 3.26 ENST00000447367.6
ENST00000382152.7
potassium voltage-gated channel interacting protein 4
chr2_-_182522703 3.22 ENST00000410103.1
phosphodiesterase 1A
chr5_+_126423363 3.21 ENST00000285689.8
GRAM domain containing 2B
chr4_-_167234552 3.21 ENST00000512648.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr11_-_35419899 3.21 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
solute carrier family 1 member 2
chr5_-_161546970 3.16 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr12_+_40828173 3.09 ENST00000552913.5
contactin 1
chr5_+_141382702 3.05 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr4_-_86360071 3.03 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr3_-_155293665 2.95 ENST00000489090.2
small transmembrane regulator of ion transport 1
chr17_-_40665121 2.90 ENST00000394052.5
keratin 222
chr2_-_166149120 2.88 ENST00000641575.1
ENST00000641603.1
sodium voltage-gated channel alpha subunit 1
chr2_-_182242031 2.88 ENST00000358139.6
phosphodiesterase 1A
chr19_-_46428869 2.84 ENST00000617053.3
PNMA family member 8C
chrX_-_32155462 2.80 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr5_+_126423122 2.73 ENST00000515200.5
GRAM domain containing 2B
chr4_+_87832917 2.64 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr7_+_120273129 2.60 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr12_+_57610150 2.52 ENST00000333972.11
Rho guanine nucleotide exchange factor 25
chr9_+_35042213 2.45 ENST00000378745.3
ENST00000312292.6
chromosome 9 open reading frame 131
chr5_+_175861628 2.44 ENST00000509837.5
complexin 2
chr19_-_43619591 2.44 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr10_+_24449426 2.43 ENST00000307544.10
KIAA1217
chr5_+_36608146 2.43 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr14_+_66824439 2.42 ENST00000555456.1
gephyrin
chr16_-_695946 2.42 ENST00000562563.1
F-box and leucine rich repeat protein 16
chr1_-_193186599 2.41 ENST00000367434.5
beta-1,3-galactosyltransferase 2
chrX_-_33211462 2.40 ENST00000682071.1
ENST00000684237.1
dystrophin
chrX_-_72877864 2.38 ENST00000596389.5
DMRT like family C1
chr17_+_68515399 2.37 ENST00000588188.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr3_+_35680932 2.36 ENST00000396481.6
cAMP regulated phosphoprotein 21
chr17_-_52158678 2.36 ENST00000451037.7
carbonic anhydrase 10
chr10_-_126670686 2.36 ENST00000488181.3
chromosome 10 open reading frame 90
chr12_+_40692413 2.35 ENST00000551295.7
ENST00000547702.5
ENST00000551424.5
contactin 1
chr3_-_196515315 2.34 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr1_-_151372683 2.34 ENST00000458566.5
ENST00000447402.7
ENST00000426705.6
ENST00000368868.10
selenium binding protein 1
chr2_-_100417608 2.31 ENST00000264249.8
carbohydrate sulfotransferase 10
chr9_-_92536067 2.28 ENST00000444490.6
extracellular matrix protein 2
chr10_+_66926028 2.28 ENST00000361320.5
leucine rich repeat transmembrane neuronal 3
chr2_-_166149204 2.27 ENST00000635750.1
sodium voltage-gated channel alpha subunit 1
chr5_+_150601060 2.22 ENST00000394243.5
synaptopodin
chr16_+_56191476 2.21 ENST00000262493.12
G protein subunit alpha o1
chr2_+_186694007 2.20 ENST00000304698.10
family with sequence similarity 171 member B
chr16_-_21303036 2.13 ENST00000219599.8
ENST00000576703.5
crystallin mu
chrM_+_5824 2.11 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr5_+_141373878 2.04 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr7_+_123601815 1.99 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr4_-_151227881 1.99 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr1_+_77918128 1.98 ENST00000342754.5
nexilin F-actin binding protein
chr3_-_186109067 1.96 ENST00000306376.10
ETS variant transcription factor 5
chr13_+_113044632 1.93 ENST00000397021.5
MCF.2 cell line derived transforming sequence like
chr11_-_57237183 1.91 ENST00000606794.1
apelin receptor
chr13_+_113044714 1.90 ENST00000423251.1
MCF.2 cell line derived transforming sequence like
chr18_-_50819982 1.90 ENST00000398439.8
ENST00000431965.6
ENST00000436348.6
maestro
chr1_+_59310071 1.89 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr9_-_15472732 1.89 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chrX_-_112840815 1.88 ENST00000304758.5
ENST00000371959.9
angiomotin
chr17_+_41966787 1.87 ENST00000393892.8
ENST00000587679.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chrX_-_81201886 1.86 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr12_-_91179472 1.86 ENST00000550099.5
ENST00000546391.5
decorin
chr16_+_7332744 1.86 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr20_+_59628609 1.84 ENST00000541461.5
phosphatase and actin regulator 3
chr19_+_18615976 1.83 ENST00000594709.1
transmembrane protein 59 like
chr8_+_30638562 1.78 ENST00000517349.2
small integral membrane protein 18
chr22_+_30080460 1.78 ENST00000336726.11
HORMA domain containing 2
chr3_-_33645433 1.74 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr5_-_42811884 1.74 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr1_+_27773189 1.72 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr2_+_165239432 1.69 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chr12_+_78964035 1.67 ENST00000547046.5
synaptotagmin 1
chr5_-_41794547 1.66 ENST00000510634.5
3-oxoacid CoA-transferase 1
chr7_+_151956440 1.65 ENST00000392800.7
ENST00000616416.4
polypeptide N-acetylgalactosaminyltransferase like 5
chr7_-_100428657 1.64 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr17_+_62370218 1.64 ENST00000450662.7
EF-hand calcium binding domain 3
chr11_+_8019193 1.62 ENST00000534099.5
TUB bipartite transcription factor
chr6_-_52994248 1.61 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr2_+_167187283 1.60 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr4_-_175787382 1.59 ENST00000507520.5
glycoprotein M6A
chr5_-_41794211 1.58 ENST00000512084.5
3-oxoacid CoA-transferase 1
chr8_-_118621901 1.57 ENST00000409003.5
ENST00000524796.6
ENST00000314727.9
sterile alpha motif domain containing 12
chr5_-_161546671 1.57 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr18_-_36067524 1.57 ENST00000590898.5
ENST00000357384.8
ENST00000399022.9
ENST00000588737.5
regulation of nuclear pre-mRNA domain containing 1A
chr10_-_27243019 1.57 ENST00000679293.1
acyl-CoA binding domain containing 5
chr2_-_174846405 1.57 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr5_+_42756811 1.56 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chr5_-_11588796 1.55 ENST00000513598.5
catenin delta 2
chr12_-_10172117 1.54 ENST00000545927.5
ENST00000309539.8
ENST00000432556.6
ENST00000544577.5
oxidized low density lipoprotein receptor 1
chr19_-_48513161 1.49 ENST00000673139.1
lemur tyrosine kinase 3
chr3_-_74521140 1.49 ENST00000263665.6
contactin 3
chr14_-_80231052 1.48 ENST00000557010.5
iodothyronine deiodinase 2
chr11_-_57324907 1.48 ENST00000358252.8
tankyrase 1 binding protein 1
chr1_-_6554501 1.46 ENST00000377705.6
nucleolar protein 9
chr15_+_70936487 1.45 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chrX_+_10158448 1.44 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr2_+_209579399 1.43 ENST00000360351.8
microtubule associated protein 2
chr5_+_141968886 1.42 ENST00000347642.7
ring finger protein 14
chr3_+_148791058 1.42 ENST00000491148.5
carboxypeptidase B1
chr1_-_109393197 1.42 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr10_-_71737824 1.41 ENST00000398786.2
chromosome 10 open reading frame 105
chr12_+_51590873 1.41 ENST00000667214.1
ENST00000662684.1
ENST00000638820.1
sodium voltage-gated channel alpha subunit 8
chr1_+_248030070 1.41 ENST00000642011.1
ENST00000641771.1
olfactory receptor family 2 subfamily L member 2
chr4_-_185649524 1.40 ENST00000451974.5
sorbin and SH3 domain containing 2
chr1_+_170663134 1.40 ENST00000367760.7
paired related homeobox 1
chr12_-_91180365 1.38 ENST00000547937.5
decorin
chr5_+_141402764 1.38 ENST00000573521.2
ENST00000616887.1
protocadherin gamma subfamily A, 9
chr12_-_121669646 1.35 ENST00000355329.7
MORN repeat containing 3
chr4_-_113517607 1.35 ENST00000509594.1
calcium/calmodulin dependent protein kinase II delta
chr9_-_92536031 1.34 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr4_-_139084191 1.33 ENST00000512627.1
E74 like ETS transcription factor 2
chr7_-_108240049 1.32 ENST00000379022.8
neuronal cell adhesion molecule
chr2_+_165239388 1.32 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr13_+_108596152 1.29 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr11_-_40293102 1.28 ENST00000527150.5
leucine rich repeat containing 4C
chr6_+_125153846 1.27 ENST00000528193.5
TPD52 like 1
chr8_-_13604574 1.27 ENST00000631382.1
DLC1 Rho GTPase activating protein
chr3_-_197184131 1.26 ENST00000452595.5
discs large MAGUK scaffold protein 1
chr2_-_55010348 1.25 ENST00000394609.6
reticulon 4
chr3_-_73433904 1.25 ENST00000479530.5
PDZ domain containing ring finger 3
chr6_+_125153793 1.24 ENST00000527711.5
TPD52 like 1
chr9_-_14322320 1.23 ENST00000606230.2
nuclear factor I B
chr16_-_70801131 1.23 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr9_-_34458533 1.21 ENST00000379089.5
ENST00000379087.5
ENST00000379084.5
ENST00000379081.5
ENST00000379080.5
ENST00000422409.5
ENST00000379078.1
ENST00000651358.1
ENST00000445726.5
ENST00000297620.8
family with sequence similarity 219 member A
chr1_-_79188390 1.20 ENST00000662530.1
adhesion G protein-coupled receptor L4
chr18_-_27143024 1.20 ENST00000581714.5
carbohydrate sulfotransferase 9
chr15_-_74366178 1.18 ENST00000450547.1
ENST00000358632.8
cytochrome P450 family 11 subfamily A member 1
chr12_-_91179355 1.17 ENST00000550563.5
ENST00000546370.5
decorin
chr16_-_31428325 1.16 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr2_+_15591733 1.16 ENST00000678786.1
ENST00000676937.1
ENST00000676916.1
ENST00000617198.5
ENST00000233084.8
ENST00000678137.1
ENST00000678594.1
ENST00000621973.2
ENST00000678391.1
DEAD-box helicase 1
chr17_-_10549612 1.16 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr3_-_73561608 1.15 ENST00000466780.5
PDZ domain containing ring finger 3
chr4_+_157221598 1.12 ENST00000505888.1
glutamate ionotropic receptor AMPA type subunit 2
chr16_+_76277269 1.12 ENST00000377504.8
ENST00000307431.12
contactin associated protein family member 4
chr4_-_184773718 1.12 ENST00000505492.1
acyl-CoA synthetase long chain family member 1
chr2_+_167187364 1.12 ENST00000672671.1
xin actin binding repeat containing 2
chr12_-_84892120 1.11 ENST00000680379.1
solute carrier family 6 member 15
chr1_+_103617427 1.10 ENST00000423678.2
ENST00000414303.7
amylase alpha 2A
chr16_+_83971451 1.10 ENST00000565691.5
N-terminal EF-hand calcium binding protein 2
chr1_+_50108856 1.09 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr1_+_53459391 1.09 ENST00000371445.3
DMRT like family B with proline rich C-terminal 1
chr1_-_179143044 1.07 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr5_-_36151853 1.06 ENST00000296603.5
LMBR1 domain containing 2
chr10_-_125881282 1.06 ENST00000284690.4
DEAH-box helicase 32 (putative)
chr16_-_10559135 1.06 ENST00000536829.1
epithelial membrane protein 2
chr11_+_124954108 1.06 ENST00000529051.5
coiled-coil domain containing 15
chr7_+_151956379 1.04 ENST00000431418.6
polypeptide N-acetylgalactosaminyltransferase like 5
chr6_+_29461440 1.04 ENST00000396792.2
olfactory receptor family 2 subfamily H member 1
chr15_-_29821473 1.02 ENST00000400011.6
tight junction protein 1
chrX_+_28587411 1.00 ENST00000378993.6
interleukin 1 receptor accessory protein like 1
chr8_-_64798725 0.99 ENST00000310193.4
cytochrome P450 family 7 subfamily B member 1
chr12_-_70754631 0.99 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr3_+_40100007 0.99 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr7_-_38909174 0.98 ENST00000395969.6
ENST00000310301.9
ENST00000414632.5
VPS41 subunit of HOPS complex
chr3_+_107377433 0.98 ENST00000261058.3
coiled-coil domain containing 54
chr9_-_14180779 0.98 ENST00000380924.1
ENST00000543693.5
nuclear factor I B
chr11_+_22338333 0.97 ENST00000263160.4
solute carrier family 17 member 6
chr3_-_96618225 0.97 ENST00000600213.3
MT-RNR2 like 12
chr6_+_168017873 0.94 ENST00000351261.4
ENST00000354419.6
kinesin family member 25
chr1_-_79188467 0.94 ENST00000656300.1
adhesion G protein-coupled receptor L4
chr10_+_93757831 0.94 ENST00000629035.2
leucine rich glioma inactivated 1
chr7_-_130441136 0.94 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr21_-_41926680 0.93 ENST00000329623.11
C2 calcium dependent domain containing 2
chr1_+_244969869 0.92 ENST00000366523.5
EF-hand calcium binding domain 2
chr5_+_160009113 0.90 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
tetratricopeptide repeat domain 1
chr3_+_173398438 0.90 ENST00000457714.5
neuroligin 1
chr5_-_134367070 0.90 ENST00000521118.5
cyclin dependent kinase like 3
chr11_-_89065945 0.90 ENST00000393294.3
glutamate metabotropic receptor 5
chr5_+_141330494 0.88 ENST00000517417.3
ENST00000378105.4
protocadherin gamma subfamily A, 1
chr6_-_47309898 0.87 ENST00000296861.2
TNF receptor superfamily member 21
chr10_-_30629741 0.86 ENST00000647634.2
ENST00000375318.4
lysozyme like 2
chrX_-_55182442 0.85 ENST00000545075.3
MT-RNR2 like 10
chr12_-_10909562 0.84 ENST00000390677.2
taste 2 receptor member 13
chr16_+_76277393 0.84 ENST00000611870.5
contactin associated protein family member 4
chr22_+_44752552 0.83 ENST00000389774.6
ENST00000356099.11
ENST00000396119.6
ENST00000336963.8
ENST00000412433.5
Rho GTPase activating protein 8
chr10_-_122699836 0.83 ENST00000329446.5
chromosome 10 open reading frame 120

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0006601 creatine biosynthetic process(GO:0006601)
2.2 6.6 GO:0006533 aspartate catabolic process(GO:0006533)
1.0 21.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.9 4.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.8 2.4 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.6 10.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 1.9 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.6 4.8 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.4 3.7 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.4 3.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.4 10.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.4 2.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 4.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 6.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.0 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.3 5.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 8.2 GO:0071420 cellular response to histamine(GO:0071420)
0.3 1.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 1.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 0.9 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 0.9 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.2 2.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 1.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.2 0.9 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 1.9 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 1.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 3.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 2.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 3.4 GO:0042908 xenobiotic transport(GO:0042908)
0.2 3.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 1.6 GO:0030242 pexophagy(GO:0030242)
0.2 3.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.2 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 1.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.8 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 9.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 2.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 2.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.7 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 1.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 3.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.5 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 2.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 5.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 2.0 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.3 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.5 GO:0045356 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 1.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.6 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.1 9.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 2.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.1 GO:0070836 caveola assembly(GO:0070836)
0.1 1.3 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.1 GO:0015820 leucine transport(GO:0015820)
0.1 1.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 9.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 1.4 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 2.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.8 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 2.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.5 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 1.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.9 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 2.8 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.9 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.6 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.6 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 2.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 9.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 8.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 1.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.6 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 1.7 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 1.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 1.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 2.7 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 2.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.4 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 2.7 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 3.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.7 GO:0060074 synapse maturation(GO:0060074)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.9 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 2.2 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.5 GO:0003407 neural retina development(GO:0003407)
0.0 1.1 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 1.7 GO:0048278 vesicle docking(GO:0048278)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.0 1.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 2.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.8 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 2.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0097444 spine apparatus(GO:0097444)
0.4 5.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 9.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 5.2 GO:0016013 syntrophin complex(GO:0016013)
0.3 2.4 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 1.2 GO:0071920 cleavage body(GO:0071920)
0.2 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 1.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 4.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 1.7 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 3.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 8.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 1.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 3.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 4.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.6 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 9.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.2 GO:0030673 axolemma(GO:0030673)
0.1 2.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 2.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.5 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 4.1 GO:0043034 costamere(GO:0043034)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 5.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 13.3 GO:0043209 myelin sheath(GO:0043209)
0.0 4.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 2.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 5.9 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.8 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 15.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 3.1 GO:0005901 caveola(GO:0005901)
0.0 13.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 2.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.2 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.5 GO:0030017 sarcomere(GO:0030017)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 5.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 7.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.6 9.7 GO:0004522 ribonuclease A activity(GO:0004522)
0.8 6.6 GO:0004046 aminoacylase activity(GO:0004046)
0.8 8.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 3.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.8 4.8 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.8 2.4 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.8 7.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 3.6 GO:0070052 collagen V binding(GO:0070052)
0.7 10.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 16.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.5 2.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 2.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 1.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.5 1.9 GO:0019150 D-ribulokinase activity(GO:0019150)
0.5 1.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.5 3.7 GO:0005499 vitamin D binding(GO:0005499)
0.4 1.4 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.3 2.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 0.9 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.3 1.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.3 9.6 GO:0002162 dystroglycan binding(GO:0002162)
0.3 5.6 GO:0008430 selenium binding(GO:0008430)
0.2 1.5 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 9.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.2 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.2 3.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 1.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 0.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 2.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.6 GO:0032427 GBD domain binding(GO:0032427)
0.2 6.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 3.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.9 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 1.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 3.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 3.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.7 GO:0097016 L27 domain binding(GO:0097016)
0.1 2.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 2.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 5.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 3.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.5 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 2.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 1.0 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.7 GO:0042805 actinin binding(GO:0042805)
0.0 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.9 GO:0003796 lysozyme activity(GO:0003796)
0.0 7.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 7.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 4.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 12.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 1.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 4.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 3.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 18.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 12.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 5.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 4.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 7.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 4.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 4.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.7 PID P73PATHWAY p73 transcription factor network
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 10.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 8.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 1.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 5.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 12.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 5.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 3.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 5.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.0 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 4.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 3.5 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 4.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway