ISMARA results: POU3F3

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Illumina Body Map 2 (GSE30611)

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Results for POU3F3_POU3F4

Z-value: 1.58

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol	Gene ID	Gene Info
POU3F3 Ensembl NCBI GeneCards UniProt	ENSG00000198914.5	POU class 3 homeobox 3
POU3F4 Ensembl NCBI GeneCards UniProt	ENSG00000196767.9	POU class 3 homeobox 4

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
POU3F3	hg38_v1_chr2_+_104854104_104854124	0.49	4.5e-03	Click!
POU3F4	hg38_v1_chrX_+_83508284_83508309	0.09	6.1e-01	Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_167234426 Show fit	7.22	ENST00000541354.5 ENST00000509854.5 ENST00000512681.5 ENST00000357545.9 ENST00000510741.5 ENST00000510403.5	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_-_46491956 Show fit	7.16	ENST00000306764.11	RCAN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of calcineurin 2
chr15_-_45378519 Show fit	6.64	ENST00000558163.1 ENST00000396659.8 ENST00000675323.1 ENST00000558336.5	GATM Ensembl NCBI GeneCards UniProt Show fit	glycine amidinotransferase
chr17_+_3475959 Show fit	6.56	ENST00000263080.3	ASPA Ensembl NCBI GeneCards UniProt Show fit	aspartoacylase
chr4_-_167234579 Show fit	5.85	ENST00000502330.5 ENST00000357154.7 ENST00000421836.6	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr3_-_58627596 Show fit	5.53	ENST00000474531.5 ENST00000465970.1	FAM107A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member A
chr3_+_159069252 Show fit	5.53	ENST00000640015.1 ENST00000476809.7 ENST00000485419.7	IQCJ-SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	IQCJ-SCHIP1 readthrough
chr12_+_40827992 Show fit	5.06	ENST00000547849.5	CNTN1 Ensembl NCBI GeneCards UniProt Show fit	contactin 1
chr14_-_20802836 Show fit	4.97	ENST00000397967.5 ENST00000555698.5 ENST00000397970.4 ENST00000340900.3	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr19_+_735026 Show fit	4.85	ENST00000592155.5 ENST00000590161.2	PALM Ensembl NCBI GeneCards UniProt Show fit	paralemmin
chr9_+_74615582 Show fit	4.77	ENST00000396204.2	RORB Ensembl NCBI GeneCards UniProt Show fit	RAR related orphan receptor B
chr14_-_20802402 Show fit	4.71	ENST00000412779.2	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr11_-_35420017 Show fit	4.59	ENST00000643000.1 ENST00000646099.1 ENST00000647372.1 ENST00000642578.1	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr5_-_11589019 Show fit	4.46	ENST00000511377.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr8_-_144605699 Show fit	4.09	ENST00000377307.6 ENST00000276826.5	ARHGAP39 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 39
chr3_+_35681352 Show fit	3.96	ENST00000436702.5 ENST00000438071.1	ARPP21 Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 21
chr2_-_182522556 Show fit	3.89	ENST00000435564.5	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr8_-_90082871 Show fit	3.74	ENST00000265431.7	CALB1 Ensembl NCBI GeneCards UniProt Show fit	calbindin 1
chr3_+_35680994 Show fit	3.63	ENST00000441454.5	ARPP21 Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 21
chr5_+_126423176 Show fit	3.62	ENST00000542322.5 ENST00000544396.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr5_+_141121793 Show fit	3.57	ENST00000194152.4	PCDHB4 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 4
chr7_-_14841267 Show fit	3.54	ENST00000406247.7 ENST00000399322.7	DGKB Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase beta
chr5_-_79514127 Show fit	3.48	ENST00000334082.11	HOMER1 Ensembl NCBI GeneCards UniProt Show fit	homer scaffold protein 1
chr5_-_161546708 Show fit	3.43	ENST00000393959.6	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr17_-_68955332 Show fit	3.43	ENST00000269080.6 ENST00000615593.4 ENST00000586539.6 ENST00000430352.6	ABCA8 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 8
chr5_-_11588842 Show fit	3.31	ENST00000503622.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr4_-_21948733 Show fit	3.26	ENST00000447367.6 ENST00000382152.7	KCNIP4 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel interacting protein 4
chr2_-_182522703 Show fit	3.22	ENST00000410103.1	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr5_+_126423363 Show fit	3.21	ENST00000285689.8	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr4_-_167234552 Show fit	3.21	ENST00000512648.5	SPOCK3 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr11_-_35419899 Show fit	3.21	ENST00000646847.1 ENST00000449068.2 ENST00000643401.1 ENST00000645966.1 ENST00000647104.1	SLC1A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 2
chr5_-_161546970 Show fit	3.16	ENST00000675303.1	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr12_+_40828173 Show fit	3.09	ENST00000552913.5	CNTN1 Ensembl NCBI GeneCards UniProt Show fit	contactin 1
chr5_+_141382702 Show fit	3.05	ENST00000617050.1 ENST00000518325.2	PCDHGA7 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 7
chr4_-_86360071 Show fit	3.03	ENST00000641677.1 ENST00000639234.1 ENST00000641553.1 ENST00000641826.1 ENST00000641537.1 ENST00000395169.9 ENST00000641408.1 ENST00000638225.1 ENST00000641052.1	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr3_-_155293665 Show fit	2.95	ENST00000489090.2	STRIT1 Ensembl NCBI GeneCards UniProt Show fit	small transmembrane regulator of ion transport 1
chr17_-_40665121 Show fit	2.90	ENST00000394052.5	KRT222 Ensembl NCBI GeneCards UniProt Show fit	keratin 222
chr2_-_166149120 Show fit	2.88	ENST00000641575.1 ENST00000641603.1	SCN1A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 1
chr2_-_182242031 Show fit	2.88	ENST00000358139.6	PDE1A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 1A
chr19_-_46428869 Show fit	2.84	ENST00000617053.3	PNMA8C Ensembl NCBI GeneCards UniProt Show fit	PNMA family member 8C
chrX_-_32155462 Show fit	2.80	ENST00000359836.5 ENST00000378707.7 ENST00000541735.5 ENST00000684130.1 ENST00000682238.1 ENST00000620040.5 ENST00000474231.5	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chr5_+_126423122 Show fit	2.73	ENST00000515200.5	GRAMD2B Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr4_+_87832917 Show fit	2.64	ENST00000395102.8 ENST00000497649.6 ENST00000540395.1 ENST00000560249.5 ENST00000511670.5 ENST00000361056.3	MEPE Ensembl NCBI GeneCards UniProt Show fit	matrix extracellular phosphoglycoprotein
chr7_+_120273129 Show fit	2.60	ENST00000331113.9	KCND2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily D member 2
chr12_+_57610150 Show fit	2.52	ENST00000333972.11	ARHGEF25 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 25
chr9_+_35042213 Show fit	2.45	ENST00000378745.3 ENST00000312292.6	C9orf131 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 131
chr5_+_175861628 Show fit	2.44	ENST00000509837.5	CPLX2 Ensembl NCBI GeneCards UniProt Show fit	complexin 2
chr19_-_43619591 Show fit	2.44	ENST00000598676.1 ENST00000300811.8	ZNF428 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 428
chr10_+_24449426 Show fit	2.43	ENST00000307544.10	KIAA1217 Ensembl NCBI GeneCards UniProt Show fit	KIAA1217
chr5_+_36608146 Show fit	2.43	ENST00000381918.4 ENST00000513646.1	SLC1A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 3
chr14_+_66824439 Show fit	2.42	ENST00000555456.1	GPHN Ensembl NCBI GeneCards UniProt Show fit	gephyrin
chr16_-_695946 Show fit	2.42	ENST00000562563.1	FBXL16 Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine rich repeat protein 16
chr1_-_193186599 Show fit	2.41	ENST00000367434.5	B3GALT2 Ensembl NCBI GeneCards UniProt Show fit	beta-1,3-galactosyltransferase 2
chrX_-_33211462 Show fit	2.40	ENST00000682071.1 ENST00000684237.1	DMD Ensembl NCBI GeneCards UniProt Show fit	dystrophin
chrX_-_72877864 Show fit	2.38	ENST00000596389.5	DMRTC1 Ensembl NCBI GeneCards UniProt Show fit	DMRT like family C1
chr17_+_68515399 Show fit	2.37	ENST00000588188.6	PRKAR1A Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit alpha
chr3_+_35680932 Show fit	2.36	ENST00000396481.6	ARPP21 Ensembl NCBI GeneCards UniProt Show fit	cAMP regulated phosphoprotein 21
chr17_-_52158678 Show fit	2.36	ENST00000451037.7	CA10 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 10
chr10_-_126670686 Show fit	2.36	ENST00000488181.3	C10orf90 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 90
chr12_+_40692413 Show fit	2.35	ENST00000551295.7 ENST00000547702.5 ENST00000551424.5	CNTN1 Ensembl NCBI GeneCards UniProt Show fit	contactin 1
chr3_-_196515315 Show fit	2.34	ENST00000397537.3	SMCO1 Ensembl NCBI GeneCards UniProt Show fit	single-pass membrane protein with coiled-coil domains 1
chr1_-_151372683 Show fit	2.34	ENST00000458566.5 ENST00000447402.7 ENST00000426705.6 ENST00000368868.10	SELENBP1 Ensembl NCBI GeneCards UniProt Show fit	selenium binding protein 1
chr2_-_100417608 Show fit	2.31	ENST00000264249.8	CHST10 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 10
chr9_-_92536067 Show fit	2.28	ENST00000444490.6	ECM2 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 2
chr10_+_66926028 Show fit	2.28	ENST00000361320.5	LRRTM3 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 3
chr2_-_166149204 Show fit	2.27	ENST00000635750.1	SCN1A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 1
chr5_+_150601060 Show fit	2.22	ENST00000394243.5	SYNPO Ensembl NCBI GeneCards UniProt Show fit	synaptopodin
chr16_+_56191476 Show fit	2.21	ENST00000262493.12	GNAO1 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha o1
chr2_+_186694007 Show fit	2.20	ENST00000304698.10	FAM171B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 171 member B
chr16_-_21303036 Show fit	2.13	ENST00000219599.8 ENST00000576703.5	CRYM Ensembl NCBI GeneCards UniProt Show fit	crystallin mu
chrM_+_5824 Show fit	2.11	ENST00000361624.2	MT-CO1 Ensembl NCBI GeneCards UniProt Show fit	mitochondrially encoded cytochrome c oxidase I
chr5_+_141373878 Show fit	2.04	ENST00000517434.3 ENST00000610583.1	PCDHGA6 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 6
chr7_+_123601815 Show fit	1.99	ENST00000451215.6	ASB15 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 15
chr4_-_151227881 Show fit	1.99	ENST00000652233.1 ENST00000514152.5	SH3D19 Ensembl NCBI GeneCards UniProt Show fit	SH3 domain containing 19
chr1_+_77918128 Show fit	1.98	ENST00000342754.5	NEXN Ensembl NCBI GeneCards UniProt Show fit	nexilin F-actin binding protein
chr3_-_186109067 Show fit	1.96	ENST00000306376.10	ETV5 Ensembl NCBI GeneCards UniProt Show fit	ETS variant transcription factor 5
chr13_+_113044632 Show fit	1.93	ENST00000397021.5	MCF2L Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence like
chr11_-_57237183 Show fit	1.91	ENST00000606794.1	APLNR Ensembl NCBI GeneCards UniProt Show fit	apelin receptor
chr13_+_113044714 Show fit	1.90	ENST00000423251.1	MCF2L Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence like
chr18_-_50819982 Show fit	1.90	ENST00000398439.8 ENST00000431965.6 ENST00000436348.6	MRO Ensembl NCBI GeneCards UniProt Show fit	maestro
chr1_+_59310071 Show fit	1.89	ENST00000371212.5	FGGY Ensembl NCBI GeneCards UniProt Show fit	FGGY carbohydrate kinase domain containing
chr9_-_15472732 Show fit	1.89	ENST00000481862.1	PSIP1 Ensembl NCBI GeneCards UniProt Show fit	PC4 and SFRS1 interacting protein 1
chrX_-_112840815 Show fit	1.88	ENST00000304758.5 ENST00000371959.9	AMOT Ensembl NCBI GeneCards UniProt Show fit	angiomotin
chr17_+_41966787 Show fit	1.87	ENST00000393892.8 ENST00000587679.1	CNP Ensembl NCBI GeneCards UniProt Show fit	2',3'-cyclic nucleotide 3' phosphodiesterase
chrX_-_81201886 Show fit	1.86	ENST00000451455.1 ENST00000358130.7 ENST00000436386.5	HMGN5 Ensembl NCBI GeneCards UniProt Show fit	high mobility group nucleosome binding domain 5
chr12_-_91179472 Show fit	1.86	ENST00000550099.5 ENST00000546391.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr16_+_7332744 Show fit	1.86	ENST00000436368.6 ENST00000311745.9 ENST00000340209.8 ENST00000620507.4	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr20_+_59628609 Show fit	1.84	ENST00000541461.5	PHACTR3 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 3
chr19_+_18615976 Show fit	1.83	ENST00000594709.1	TMEM59L Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 59 like
chr8_+_30638562 Show fit	1.78	ENST00000517349.2	SMIM18 Ensembl NCBI GeneCards UniProt Show fit	small integral membrane protein 18
chr22_+_30080460 Show fit	1.78	ENST00000336726.11	HORMAD2 Ensembl NCBI GeneCards UniProt Show fit	HORMA domain containing 2
chr3_-_33645433 Show fit	1.74	ENST00000635664.1 ENST00000485378.6 ENST00000313350.10 ENST00000487200.5	CLASP2 Ensembl NCBI GeneCards UniProt Show fit	cytoplasmic linker associated protein 2
chr5_-_42811884 Show fit	1.74	ENST00000514985.6 ENST00000511224.5 ENST00000507920.5 ENST00000510965.1	SELENOP Ensembl NCBI GeneCards UniProt Show fit	selenoprotein P
chr1_+_27773189 Show fit	1.72	ENST00000373943.9 ENST00000440806.2	STX12 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 12
chr2_+_165239432 Show fit	1.69	ENST00000636071.2 ENST00000636985.2	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr12_+_78964035 Show fit	1.67	ENST00000547046.5	SYT1 Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin 1
chr5_-_41794547 Show fit	1.66	ENST00000510634.5	OXCT1 Ensembl NCBI GeneCards UniProt Show fit	3-oxoacid CoA-transferase 1
chr7_+_151956440 Show fit	1.65	ENST00000392800.7 ENST00000616416.4	GALNTL5 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase like 5
chr7_-_100428657 Show fit	1.64	ENST00000360951.8 ENST00000398027.6 ENST00000684423.1 ENST00000472716.1	ZCWPW1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CW-type and PWWP domain containing 1
chr17_+_62370218 Show fit	1.64	ENST00000450662.7	EFCAB3 Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 3
chr11_+_8019193 Show fit	1.62	ENST00000534099.5	TUB Ensembl NCBI GeneCards UniProt Show fit	TUB bipartite transcription factor
chr6_-_52994248 Show fit	1.61	ENST00000457564.1 ENST00000370960.5	GSTA4 Ensembl NCBI GeneCards UniProt Show fit	glutathione S-transferase alpha 4
chr2_+_167187283 Show fit	1.60	ENST00000409605.1 ENST00000409273.6	XIRP2 Ensembl NCBI GeneCards UniProt Show fit	xin actin binding repeat containing 2
chr4_-_175787382 Show fit	1.59	ENST00000507520.5	GPM6A Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6A
chr5_-_41794211 Show fit	1.58	ENST00000512084.5	OXCT1 Ensembl NCBI GeneCards UniProt Show fit	3-oxoacid CoA-transferase 1
chr8_-_118621901 Show fit	1.57	ENST00000409003.5 ENST00000524796.6 ENST00000314727.9	SAMD12 Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 12
chr5_-_161546671 Show fit	1.57	ENST00000517547.5	GABRB2 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit beta2
chr18_-_36067524 Show fit	1.57	ENST00000590898.5 ENST00000357384.8 ENST00000399022.9 ENST00000588737.5	RPRD1A Ensembl NCBI GeneCards UniProt Show fit	regulation of nuclear pre-mRNA domain containing 1A
chr10_-_27243019 Show fit	1.57	ENST00000679293.1	ACBD5 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA binding domain containing 5
chr2_-_174846405 Show fit	1.57	ENST00000409597.5 ENST00000413882.6	CHN1 Ensembl NCBI GeneCards UniProt Show fit	chimerin 1
chr5_+_42756811 Show fit	1.56	ENST00000388827.4 ENST00000361970.10	CCDC152 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 152
chr5_-_11588796 Show fit	1.55	ENST00000513598.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr12_-_10172117 Show fit	1.54	ENST00000545927.5 ENST00000309539.8 ENST00000432556.6 ENST00000544577.5	OLR1 Ensembl NCBI GeneCards UniProt Show fit	oxidized low density lipoprotein receptor 1
chr19_-_48513161 Show fit	1.49	ENST00000673139.1	LMTK3 Ensembl NCBI GeneCards UniProt Show fit	lemur tyrosine kinase 3
chr3_-_74521140 Show fit	1.49	ENST00000263665.6	CNTN3 Ensembl NCBI GeneCards UniProt Show fit	contactin 3
chr14_-_80231052 Show fit	1.48	ENST00000557010.5	DIO2 Ensembl NCBI GeneCards UniProt Show fit	iodothyronine deiodinase 2
chr11_-_57324907 Show fit	1.48	ENST00000358252.8	TNKS1BP1 Ensembl NCBI GeneCards UniProt Show fit	tankyrase 1 binding protein 1
chr1_-_6554501 Show fit	1.46	ENST00000377705.6	NOL9 Ensembl NCBI GeneCards UniProt Show fit	nucleolar protein 9
chr15_+_70936487 Show fit	1.45	ENST00000558456.5 ENST00000560158.6 ENST00000558808.5 ENST00000559806.5 ENST00000559069.1	LRRC49 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 49
chrX_+_10158448 Show fit	1.44	ENST00000380829.5 ENST00000421085.7 ENST00000674669.1 ENST00000454850.1	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 4
chr2_+_209579399 Show fit	1.43	ENST00000360351.8	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr5_+_141968886 Show fit	1.42	ENST00000347642.7	RNF14 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 14
chr3_+_148791058 Show fit	1.42	ENST00000491148.5	CPB1 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B1
chr1_-_109393197 Show fit	1.42	ENST00000538502.5 ENST00000482236.5	SORT1 Ensembl NCBI GeneCards UniProt Show fit	sortilin 1
chr10_-_71737824 Show fit	1.41	ENST00000398786.2	C10orf105 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 105
chr12_+_51590873 Show fit	1.41	ENST00000667214.1 ENST00000662684.1 ENST00000638820.1	SCN8A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 8
chr1_+_248030070 Show fit	1.41	ENST00000642011.1 ENST00000641771.1	OR2L2 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily L member 2
chr4_-_185649524 Show fit	1.40	ENST00000451974.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr1_+_170663134 Show fit	1.40	ENST00000367760.7	PRRX1 Ensembl NCBI GeneCards UniProt Show fit	paired related homeobox 1
chr12_-_91180365 Show fit	1.38	ENST00000547937.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr5_+_141402764 Show fit	1.38	ENST00000573521.2 ENST00000616887.1	PCDHGA9 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 9
chr12_-_121669646 Show fit	1.35	ENST00000355329.7	MORN3 Ensembl NCBI GeneCards UniProt Show fit	MORN repeat containing 3
chr4_-_113517607 Show fit	1.35	ENST00000509594.1	CAMK2D Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase II delta
chr9_-_92536031 Show fit	1.34	ENST00000344604.9 ENST00000375540.5	ECM2 Ensembl NCBI GeneCards UniProt Show fit	extracellular matrix protein 2
chr4_-_139084191 Show fit	1.33	ENST00000512627.1	ELF2 Ensembl NCBI GeneCards UniProt Show fit	E74 like ETS transcription factor 2
chr7_-_108240049 Show fit	1.32	ENST00000379022.8	NRCAM Ensembl NCBI GeneCards UniProt Show fit	neuronal cell adhesion molecule
chr2_+_165239388 Show fit	1.32	ENST00000424833.5 ENST00000375437.7 ENST00000631182.3	SCN2A Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel alpha subunit 2
chr13_+_108596152 Show fit	1.29	ENST00000356711.7 ENST00000251041.10	MYO16 Ensembl NCBI GeneCards UniProt Show fit	myosin XVI
chr11_-_40293102 Show fit	1.28	ENST00000527150.5	LRRC4C Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat containing 4C
chr6_+_125153846 Show fit	1.27	ENST00000528193.5	TPD52L1 Ensembl NCBI GeneCards UniProt Show fit	TPD52 like 1
chr8_-_13604574 Show fit	1.27	ENST00000631382.1	DLC1 Ensembl NCBI GeneCards UniProt Show fit	DLC1 Rho GTPase activating protein
chr3_-_197184131 Show fit	1.26	ENST00000452595.5	DLG1 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 1
chr2_-_55010348 Show fit	1.25	ENST00000394609.6	RTN4 Ensembl NCBI GeneCards UniProt Show fit	reticulon 4
chr3_-_73433904 Show fit	1.25	ENST00000479530.5	PDZRN3 Ensembl NCBI GeneCards UniProt Show fit	PDZ domain containing ring finger 3
chr6_+_125153793 Show fit	1.24	ENST00000527711.5	TPD52L1 Ensembl NCBI GeneCards UniProt Show fit	TPD52 like 1
chr9_-_14322320 Show fit	1.23	ENST00000606230.2	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr16_-_70801131 Show fit	1.23	ENST00000261776.10	VAC14 Ensembl NCBI GeneCards UniProt Show fit	VAC14 component of PIKFYVE complex
chr9_-_34458533 Show fit	1.21	ENST00000379089.5 ENST00000379087.5 ENST00000379084.5 ENST00000379081.5 ENST00000379080.5 ENST00000422409.5 ENST00000379078.1 ENST00000651358.1 ENST00000445726.5 ENST00000297620.8	FAM219A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 219 member A
chr1_-_79188390 Show fit	1.20	ENST00000662530.1	ADGRL4 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L4
chr18_-_27143024 Show fit	1.20	ENST00000581714.5	CHST9 Ensembl NCBI GeneCards UniProt Show fit	carbohydrate sulfotransferase 9
chr15_-_74366178 Show fit	1.18	ENST00000450547.1 ENST00000358632.8	CYP11A1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 11 subfamily A member 1
chr12_-_91179355 Show fit	1.17	ENST00000550563.5 ENST00000546370.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr16_-_31428325 Show fit	1.16	ENST00000287490.5	COX6A2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 6A2
chr2_+_15591733 Show fit	1.16	ENST00000678786.1 ENST00000676937.1 ENST00000676916.1 ENST00000617198.5 ENST00000233084.8 ENST00000678137.1 ENST00000678594.1 ENST00000621973.2 ENST00000678391.1	DDX1 Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 1
chr17_-_10549612 Show fit	1.16	ENST00000532183.6 ENST00000397183.6 ENST00000420805.1	MYH2 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 2
chr3_-_73561608 Show fit	1.15	ENST00000466780.5	PDZRN3 Ensembl NCBI GeneCards UniProt Show fit	PDZ domain containing ring finger 3
chr4_+_157221598 Show fit	1.12	ENST00000505888.1	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr16_+_76277269 Show fit	1.12	ENST00000377504.8 ENST00000307431.12	CNTNAP4 Ensembl NCBI GeneCards UniProt Show fit	contactin associated protein family member 4
chr4_-_184773718 Show fit	1.12	ENST00000505492.1	ACSL1 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 1
chr2_+_167187364 Show fit	1.12	ENST00000672671.1	XIRP2 Ensembl NCBI GeneCards UniProt Show fit	xin actin binding repeat containing 2
chr12_-_84892120 Show fit	1.11	ENST00000680379.1	SLC6A15 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 15
chr1_+_103617427 Show fit	1.10	ENST00000423678.2 ENST00000414303.7	AMY2A Ensembl NCBI GeneCards UniProt Show fit	amylase alpha 2A
chr16_+_83971451 Show fit	1.10	ENST00000565691.5	NECAB2 Ensembl NCBI GeneCards UniProt Show fit	N-terminal EF-hand calcium binding protein 2
chr1_+_50108856 Show fit	1.09	ENST00000650764.1 ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1	ELAVL4 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr1_+_53459391 Show fit	1.09	ENST00000371445.3	DMRTB1 Ensembl NCBI GeneCards UniProt Show fit	DMRT like family B with proline rich C-terminal 1
chr1_-_179143044 Show fit	1.07	ENST00000504405.5 ENST00000512653.5 ENST00000344730.7	ABL2 Ensembl NCBI GeneCards UniProt Show fit	ABL proto-oncogene 2, non-receptor tyrosine kinase
chr5_-_36151853 Show fit	1.06	ENST00000296603.5	LMBRD2 Ensembl NCBI GeneCards UniProt Show fit	LMBR1 domain containing 2
chr10_-_125881282 Show fit	1.06	ENST00000284690.4	DHX32 Ensembl NCBI GeneCards UniProt Show fit	DEAH-box helicase 32 (putative)
chr16_-_10559135 Show fit	1.06	ENST00000536829.1	EMP2 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 2
chr11_+_124954108 Show fit	1.06	ENST00000529051.5	CCDC15 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 15
chr7_+_151956379 Show fit	1.04	ENST00000431418.6	GALNTL5 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase like 5
chr6_+_29461440 Show fit	1.04	ENST00000396792.2	OR2H1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 2 subfamily H member 1
chr15_-_29821473 Show fit	1.02	ENST00000400011.6	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chrX_+_28587411 Show fit	1.00	ENST00000378993.6	IL1RAPL1 Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor accessory protein like 1
chr8_-_64798725 Show fit	0.99	ENST00000310193.4	CYP7B1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 7 subfamily B member 1
chr12_-_70754631 Show fit	0.99	ENST00000440835.6 ENST00000549308.5 ENST00000550661.1 ENST00000378778.5	PTPRR Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type R
chr3_+_40100007 Show fit	0.99	ENST00000539167.2	MYRIP Ensembl NCBI GeneCards UniProt Show fit	myosin VIIA and Rab interacting protein
chr7_-_38909174 Show fit	0.98	ENST00000395969.6 ENST00000310301.9 ENST00000414632.5	VPS41 Ensembl NCBI GeneCards UniProt Show fit	VPS41 subunit of HOPS complex
chr3_+_107377433 Show fit	0.98	ENST00000261058.3	CCDC54 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 54
chr9_-_14180779 Show fit	0.98	ENST00000380924.1 ENST00000543693.5	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr11_+_22338333 Show fit	0.97	ENST00000263160.4	SLC17A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 17 member 6
chr3_-_96618225 Show fit	0.97	ENST00000600213.3	MTRNR2L12 Ensembl NCBI GeneCards UniProt Show fit	MT-RNR2 like 12
chr6_+_168017873 Show fit	0.94	ENST00000351261.4 ENST00000354419.6	KIF25 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member 25
chr1_-_79188467 Show fit	0.94	ENST00000656300.1	ADGRL4 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L4
chr10_+_93757831 Show fit	0.94	ENST00000629035.2	LGI1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich glioma inactivated 1
chr7_-_130441136 Show fit	0.94	ENST00000675596.1 ENST00000676312.1	CEP41 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 41
chr21_-_41926680 Show fit	0.93	ENST00000329623.11	C2CD2 Ensembl NCBI GeneCards UniProt Show fit	C2 calcium dependent domain containing 2
chr1_+_244969869 Show fit	0.92	ENST00000366523.5	EFCAB2 Ensembl NCBI GeneCards UniProt Show fit	EF-hand calcium binding domain 2
chr5_+_160009113 Show fit	0.90	ENST00000522793.5 ENST00000682719.1 ENST00000684137.1 ENST00000683219.1 ENST00000684018.1 ENST00000231238.10 ENST00000682131.1	TTC1 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 1
chr3_+_173398438 Show fit	0.90	ENST00000457714.5	NLGN1 Ensembl NCBI GeneCards UniProt Show fit	neuroligin 1
chr5_-_134367070 Show fit	0.90	ENST00000521118.5	CDKL3 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase like 3
chr11_-_89065945 Show fit	0.90	ENST00000393294.3	GRM5 Ensembl NCBI GeneCards UniProt Show fit	glutamate metabotropic receptor 5
chr5_+_141330494 Show fit	0.88	ENST00000517417.3 ENST00000378105.4	PCDHGA1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily A, 1
chr6_-_47309898 Show fit	0.87	ENST00000296861.2	TNFRSF21 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 21
chr10_-_30629741 Show fit	0.86	ENST00000647634.2 ENST00000375318.4	LYZL2 Ensembl NCBI GeneCards UniProt Show fit	lysozyme like 2
chrX_-_55182442 Show fit	0.85	ENST00000545075.3	MTRNR2L10 Ensembl NCBI GeneCards UniProt Show fit	MT-RNR2 like 10
chr12_-_10909562 Show fit	0.84	ENST00000390677.2	TAS2R13 Ensembl NCBI GeneCards UniProt Show fit	taste 2 receptor member 13
chr16_+_76277393 Show fit	0.84	ENST00000611870.5	CNTNAP4 Ensembl NCBI GeneCards UniProt Show fit	contactin associated protein family member 4
chr22_+_44752552 Show fit	0.83	ENST00000389774.6 ENST00000356099.11 ENST00000396119.6 ENST00000336963.8 ENST00000412433.5	ARHGAP8 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 8
chr10_-_122699836 Show fit	0.83	ENST00000329446.5	C10orf120 Ensembl NCBI GeneCards UniProt Show fit	chromosome 10 open reading frame 120

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	6.6	GO:0006601	creatine biosynthetic process(GO:0006601)
2.2	6.6	GO:0006533	aspartate catabolic process(GO:0006533)
1.0	21.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.9	4.4	GO:0007206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.8	2.4	GO:0072579	molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.6	10.2	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6	1.9	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.6	4.8	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.4	3.7	GO:0035502	metanephric part of ureteric bud development(GO:0035502)
0.4	3.2	GO:0046952	ketone body catabolic process(GO:0046952)
0.4	10.0	GO:0046069	cGMP catabolic process(GO:0046069)
0.4	2.2	GO:0098886	modification of dendritic spine(GO:0098886)
0.4	4.8	GO:0035881	amacrine cell differentiation(GO:0035881)
0.3	6.5	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3	1.3	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
0.3	1.0	GO:0042144	vacuole fusion, non-autophagic(GO:0042144)
0.3	5.2	GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3	8.2	GO:0071420	cellular response to histamine(GO:0071420)
0.3	1.7	GO:0098746	fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3	1.3	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2	0.9	GO:0046603	negative regulation of mitotic centrosome separation(GO:0046603)
0.2	0.9	GO:0097115	cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.2	2.2	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2	1.1	GO:1904021	negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.2	0.9	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.2	1.9	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.2	1.0	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2	3.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.2	2.2	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2	2.4	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	1.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2	0.6	GO:1901253	negative regulation of intracellular transport of viral material(GO:1901253)
0.2	3.4	GO:0042908	xenobiotic transport(GO:0042908)
0.2	3.0	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2	1.6	GO:0030242	pexophagy(GO:0030242)
0.2	3.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	1.6	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.2	1.9	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.2	1.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.1	1.8	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
0.1	9.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.1	2.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	1.0	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.1	2.6	GO:0045475	locomotor rhythm(GO:0045475)
0.1	1.7	GO:1903286	regulation of potassium ion import(GO:1903286)
0.1	1.7	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	1.7	GO:0001887	selenium compound metabolic process(GO:0001887)
0.1	3.3	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	1.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.1	0.5	GO:2000612	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1	0.5	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	2.3	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004)
0.1	5.8	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	1.5	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.3	GO:0046338	phosphatidylethanolamine catabolic process(GO:0046338)
0.1	2.0	GO:2000821	regulation of grooming behavior(GO:2000821)
0.1	0.3	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	1.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	1.9	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.5	GO:0045356	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	1.3	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.5	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	1.2	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1	0.7	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1	0.6	GO:0048239	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1	1.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211) response to oleic acid(GO:0034201)
0.1	9.7	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	2.4	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	1.0	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	1.1	GO:0070836	caveola assembly(GO:0070836)
0.1	1.3	GO:0048664	neuron fate determination(GO:0048664)
0.1	1.5	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	1.1	GO:0015820	leucine transport(GO:0015820)
0.1	1.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.8	GO:2000124	regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	1.0	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	0.4	GO:0038098	sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1	9.3	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.1	1.4	GO:1901725	regulation of histone deacetylase activity(GO:1901725)
0.1	2.0	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.1	0.8	GO:0014807	regulation of somitogenesis(GO:0014807)
0.1	0.3	GO:0036367	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1	0.7	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1	1.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.9	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.4	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1	1.3	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.1	0.8	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	3.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	2.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.5	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.1	0.6	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.1	0.6	GO:0036371	protein localization to T-tubule(GO:0036371)
0.1	1.6	GO:1901685	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1	0.3	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.1	0.5	GO:0010265	SCF complex assembly(GO:0010265)
0.1	1.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.1	1.2	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1	0.9	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	1.9	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	2.8	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.9	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.6	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.6	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.8	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	2.4	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	9.9	GO:0034605	cellular response to heat(GO:0034605)
0.0	1.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	8.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	1.0	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	1.5	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.3	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	1.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	1.5	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	1.5	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	1.4	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.4	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.6	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.2	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0	1.7	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	1.6	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	1.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.5	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.4	GO:0005513	detection of calcium ion(GO:0005513)
0.0	2.7	GO:0003281	ventricular septum development(GO:0003281)
0.0	0.3	GO:2001288	positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0	2.0	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	1.4	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	1.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	2.7	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	3.3	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.7	GO:0060074	synapse maturation(GO:0060074)
0.0	0.8	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.9	GO:0002323	natural killer cell activation involved in immune response(GO:0002323)
0.0	0.3	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.6	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.4	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.4	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	2.2	GO:0006970	response to osmotic stress(GO:0006970)
0.0	1.5	GO:0003407	neural retina development(GO:0003407)
0.0	1.1	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.3	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.5	GO:0006825	copper ion transport(GO:0006825)
0.0	1.7	GO:0048278	vesicle docking(GO:0048278)
0.0	1.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.7	GO:0090383	phagosome acidification(GO:0090383)
0.0	1.2	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.3	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	2.5	GO:0046330	positive regulation of JNK cascade(GO:0046330)
0.0	0.5	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.4	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.8	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.7	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.3	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.3	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	1.3	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.5	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	2.3	GO:0007286	spermatid development(GO:0007286)
0.0	0.0	GO:0010430	fatty acid omega-oxidation(GO:0010430)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0097444	spine apparatus(GO:0097444)
0.4	5.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	9.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.3	5.2	GO:0016013	syntrophin complex(GO:0016013)
0.3	2.4	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3	1.2	GO:0071920	cleavage body(GO:0071920)
0.2	2.6	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.2	1.3	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.2	4.8	GO:0032591	dendritic spine membrane(GO:0032591)
0.2	1.7	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	3.3	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	8.2	GO:1902711	GABA-A receptor complex(GO:1902711)
0.2	0.8	GO:0070557	PCNA-p21 complex(GO:0070557)
0.1	1.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	1.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	3.0	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	1.0	GO:0033263	CORVET complex(GO:0033263)
0.1	0.3	GO:0097224	sperm connecting piece(GO:0097224)
0.1	1.6	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	4.1	GO:0005614	interstitial matrix(GO:0005614)
0.1	3.6	GO:0035748	myelin sheath abaxonal region(GO:0035748)
0.1	1.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.1	9.6	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	6.2	GO:0030673	axolemma(GO:0030673)
0.1	2.6	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.5	GO:0032437	cuticular plate(GO:0032437)
0.1	2.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	0.5	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	4.1	GO:0043034	costamere(GO:0043034)
0.1	1.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	1.3	GO:0043194	axon initial segment(GO:0043194)
0.0	1.7	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	5.8	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.8	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.5	GO:0036157	outer dynein arm(GO:0036157)
0.0	1.3	GO:0000145	exocyst(GO:0000145)
0.0	0.5	GO:0008278	cohesin complex(GO:0008278)
0.0	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	13.3	GO:0043209	myelin sheath(GO:0043209)
0.0	4.1	GO:0043195	terminal bouton(GO:0043195)
0.0	0.6	GO:0070187	telosome(GO:0070187)
0.0	2.7	GO:0031941	filamentous actin(GO:0031941)
0.0	0.7	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.6	GO:0044295	axonal growth cone(GO:0044295)
0.0	2.3	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	5.9	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.5	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.7	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	1.4	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	1.2	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.8	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	1.8	GO:0000795	synaptonemal complex(GO:0000795)
0.0	1.0	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	15.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.8	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	2.9	GO:0042734	presynaptic membrane(GO:0042734)
0.0	1.0	GO:0005921	gap junction(GO:0005921)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.5	GO:0036020	endolysosome membrane(GO:0036020)
0.0	1.0	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	3.1	GO:0005901	caveola(GO:0005901)
0.0	13.2	GO:0043025	neuronal cell body(GO:0043025)
0.0	2.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	1.8	GO:0005871	kinesin complex(GO:0005871)
0.0	1.4	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	2.2	GO:0005875	microtubule associated complex(GO:0005875)
0.0	2.9	GO:0016363	nuclear matrix(GO:0016363)
0.0	3.3	GO:0031902	late endosome membrane(GO:0031902)
0.0	1.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	3.5	GO:0030017	sarcomere(GO:0030017)
0.0	3.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	1.1	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	1.3	GO:0016459	myosin complex(GO:0016459)
0.0	0.6	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	5.1	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	7.5	GO:0043005	neuron projection(GO:0043005)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	1.2	GO:0070821	tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	10.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.6	9.7	GO:0004522	ribonuclease A activity(GO:0004522)
0.8	6.6	GO:0004046	aminoacylase activity(GO:0004046)
0.8	8.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8	3.2	GO:0008260	3-oxoacid CoA-transferase activity(GO:0008260)
0.8	4.8	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.8	2.4	GO:0008940	nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.8	7.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7	3.6	GO:0070052	collagen V binding(GO:0070052)
0.7	10.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.6	16.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.5	2.1	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5	2.6	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.5	1.5	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.5	1.9	GO:0019150	D-ribulokinase activity(GO:0019150)
0.5	1.9	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.5	3.7	GO:0005499	vitamin D binding(GO:0005499)
0.4	1.4	GO:0030379	neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.3	2.6	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.3	0.9	GO:0099530	G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.3	1.1	GO:0031687	A2A adenosine receptor binding(GO:0031687)
0.3	9.6	GO:0002162	dystroglycan binding(GO:0002162)
0.3	5.6	GO:0008430	selenium binding(GO:0008430)
0.2	1.5	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2	9.6	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2	3.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	1.2	GO:0033677	DNA/RNA helicase activity(GO:0033677)
0.2	3.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.2	1.1	GO:0005298	proline:sodium symporter activity(GO:0005298)
0.2	0.8	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2	1.7	GO:0030348	syntaxin-3 binding(GO:0030348)
0.2	2.8	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.2	0.6	GO:0032427	GBD domain binding(GO:0032427)
0.2	6.6	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.1	3.5	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	1.9	GO:0097100	supercoiled DNA binding(GO:0097100)
0.1	1.3	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	1.5	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	1.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	3.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.1	0.7	GO:0050436	microfibril binding(GO:0050436)
0.1	0.5	GO:0004802	transketolase activity(GO:0004802)
0.1	3.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	1.7	GO:0097016	L27 domain binding(GO:0097016)
0.1	2.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	1.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.5	GO:0004692	cGMP-dependent protein kinase activity(GO:0004692)
0.1	2.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.6	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1	1.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	5.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.1	1.5	GO:0033038	bitter taste receptor activity(GO:0033038)
0.1	0.1	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.1	0.8	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.9	GO:0005132	type I interferon receptor binding(GO:0005132)
0.1	3.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	0.5	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.1	0.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.6	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	1.6	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.1	1.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.3	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	0.5	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	1.0	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	2.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.5	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	1.0	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.7	GO:0042805	actinin binding(GO:0042805)
0.0	1.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	1.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.9	GO:0003796	lysozyme activity(GO:0003796)
0.0	7.6	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.2	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0	7.9	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	1.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.6	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	1.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	4.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	1.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	12.3	GO:0005516	calmodulin binding(GO:0005516)
0.0	1.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	1.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.5	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.3	GO:0032027	myosin light chain binding(GO:0032027)
0.0	1.9	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.4	GO:0042731	PH domain binding(GO:0042731)
0.0	1.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.4	GO:0036122	BMP binding(GO:0036122)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.9	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0	0.8	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.6	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.8	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	2.3	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.9	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	2.7	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	2.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	1.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	1.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	4.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	1.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.9	GO:0051018	protein kinase A binding(GO:0051018)
0.0	1.0	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.7	GO:0030507	spectrin binding(GO:0030507)
0.0	1.6	GO:0003774	motor activity(GO:0003774)
0.0	0.9	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.3	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.4	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.3	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0035276	aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.0	1.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	3.7	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	1.0	GO:0043621	protein self-association(GO:0043621)
0.0	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.0	1.6	GO:0005262	calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	18.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	12.0	PID NOTCH PATHWAY	Notch signaling pathway
0.1	5.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	2.8	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	4.7	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	7.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	4.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	2.8	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	2.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	2.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	2.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	2.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	4.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	1.7	PID P73PATHWAY	p73 transcription factor network
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.9	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2	10.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	8.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.2	1.9	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2	5.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	2.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	12.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	3.0	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	5.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	3.4	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.1	3.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	5.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	3.0	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	3.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	3.0	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	2.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	1.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	4.0	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	3.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	4.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	3.5	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	1.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	2.1	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.9	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	2.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.7	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	1.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	3.6	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway

Results for POU3F3_POU3F4

Z-value: 1.58

Motif logo

Transcription factors associated with POU3F3_POU3F4

Activity-expression correlation:

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: