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Illumina Body Map 2 (GSE30611)

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Results for POU4F1_POU4F3

Z-value: 0.94

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
ENSG00000152192.8 POU class 4 homeobox 1
ENSG00000091010.6 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F3hg38_v1_chr5_+_146338835_1463388460.241.9e-01Click!
POU4F1hg38_v1_chr13_-_78603539_786035950.019.6e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_73404255 6.73 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
albumin
chr4_-_71784046 6.00 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr14_-_64942720 4.64 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chr3_-_52826834 4.33 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain 4
chr14_-_64942783 4.25 ENST00000612794.1
glutathione peroxidase 2
chr12_+_49346885 3.80 ENST00000549441.7
DnaJ heat shock protein family (Hsp40) member C22
chr2_+_86907953 3.77 ENST00000409776.6
RANBP2 like and GRIP domain containing 1
chr11_-_35420017 2.90 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr17_-_40665121 2.89 ENST00000394052.5
keratin 222
chr12_+_51591216 2.75 ENST00000668547.1
ENST00000354534.11
ENST00000627620.5
ENST00000545061.5
sodium voltage-gated channel alpha subunit 8
chr3_-_194351290 2.68 ENST00000429275.1
ENST00000323830.4
carboxypeptidase N subunit 2
chr4_-_99290975 2.59 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr12_+_49346911 2.52 ENST00000395069.3
DnaJ heat shock protein family (Hsp40) member C22
chr9_-_121050264 2.46 ENST00000223642.3
complement C5
chr6_-_136526472 2.45 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr1_+_62597510 2.32 ENST00000371129.4
angiopoietin like 3
chr16_-_51151259 2.18 ENST00000251020.9
spalt like transcription factor 1
chr15_+_58431985 2.16 ENST00000433326.2
ENST00000299022.10
lipase C, hepatic type
chr22_+_30080460 2.06 ENST00000336726.11
HORMA domain containing 2
chr6_-_136525961 2.01 ENST00000438100.6
microtubule associated protein 7
chr6_-_136526177 2.01 ENST00000617204.4
microtubule associated protein 7
chr3_-_186109067 1.92 ENST00000306376.10
ETS variant transcription factor 5
chr12_+_40827992 1.83 ENST00000547849.5
contactin 1
chrX_-_106903331 1.80 ENST00000411805.1
ENST00000276173.5
ripply transcriptional repressor 1
chr12_+_78964035 1.68 ENST00000547046.5
synaptotagmin 1
chr1_+_50108856 1.64 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr19_-_35812838 1.61 ENST00000653904.2
proline dehydrogenase 2
chr18_+_49562049 1.52 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr12_+_40828173 1.46 ENST00000552913.5
contactin 1
chr11_-_35420050 1.40 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
solute carrier family 1 member 2
chr3_+_35680994 1.38 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr3_+_35681352 1.37 ENST00000436702.5
ENST00000438071.1
cAMP regulated phosphoprotein 21
chr2_-_55010348 1.36 ENST00000394609.6
reticulon 4
chr1_+_47137435 1.35 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
cytochrome P450 family 4 subfamily A member 22
chr2_-_208190001 1.34 ENST00000451346.5
ENST00000341287.9
chromosome 2 open reading frame 80
chr11_+_58939471 1.22 ENST00000532726.5
glycine-N-acyltransferase like 1
chr12_-_16600703 1.19 ENST00000616247.4
LIM domain only 3
chr17_+_39626944 1.19 ENST00000582680.5
ENST00000254079.9
protein phosphatase 1 regulatory inhibitor subunit 1B
chr12_+_51590873 1.18 ENST00000667214.1
ENST00000662684.1
ENST00000638820.1
sodium voltage-gated channel alpha subunit 8
chr11_-_35419899 1.15 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
solute carrier family 1 member 2
chr2_-_182522556 1.15 ENST00000435564.5
phosphodiesterase 1A
chr2_-_182522703 1.08 ENST00000410103.1
phosphodiesterase 1A
chr16_-_51151238 1.08 ENST00000566102.1
spalt like transcription factor 1
chr3_-_186108929 1.05 ENST00000413301.5
ENST00000421809.5
ETS variant transcription factor 5
chr3_+_35680932 1.03 ENST00000396481.6
cAMP regulated phosphoprotein 21
chr7_-_108240049 1.03 ENST00000379022.8
neuronal cell adhesion molecule
chr3_+_68006224 1.02 ENST00000496687.1
TAFA chemokine like family member 1
chr6_+_150368892 1.02 ENST00000229447.9
ENST00000392256.6
iodotyrosine deiodinase
chr17_-_10838075 1.01 ENST00000580256.3
ENST00000643787.1
phosphoinositide interacting regulator of transient receptor potential channels
novel transcript
chr6_+_150368997 1.00 ENST00000392255.7
ENST00000500320.7
ENST00000344419.8
iodotyrosine deiodinase
chrX_+_23664251 0.96 ENST00000379349.5
peroxiredoxin 4
chr4_-_21544650 0.96 ENST00000509207.1
potassium voltage-gated channel interacting protein 4
chr21_-_36542600 0.96 ENST00000399136.5
claudin 14
chr3_+_46701385 0.95 ENST00000643606.3
transmembrane inner ear
chr10_-_5003850 0.95 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr22_+_25069819 0.94 ENST00000401395.1
KIAA1671
chr1_-_197067234 0.93 ENST00000367412.2
coagulation factor XIII B chain
chr2_+_190356514 0.84 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr19_+_19528861 0.84 ENST00000436027.9
YjeF N-terminal domain containing 3
chr17_-_74859863 0.80 ENST00000293190.10
glutamate ionotropic receptor NMDA type subunit 2C
chr19_+_19528901 0.78 ENST00000514277.6
YjeF N-terminal domain containing 3
chr9_+_128920966 0.77 ENST00000428610.5
ENST00000372592.8
phytanoyl-CoA dioxygenase domain containing 1
chrX_-_139642889 0.77 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr1_+_100538131 0.77 ENST00000315033.5
G protein-coupled receptor 88
chr4_-_103077282 0.75 ENST00000503230.5
ENST00000503818.1
solute carrier family 9 member B2
chr10_-_77637789 0.75 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr5_+_42756811 0.75 ENST00000388827.4
ENST00000361970.10
coiled-coil domain containing 152
chr1_+_81306096 0.73 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr12_+_109573757 0.73 ENST00000228510.8
ENST00000539696.5
ENST00000392727.7
mevalonate kinase
chr18_-_26863187 0.73 ENST00000440832.7
aquaporin 4
chr17_+_39627200 0.72 ENST00000579000.5
protein phosphatase 1 regulatory inhibitor subunit 1B
chr3_+_151873634 0.72 ENST00000362032.6
succinate receptor 1
chr4_-_99321362 0.71 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr9_+_128921748 0.69 ENST00000426694.5
phytanoyl-CoA dioxygenase domain containing 1
chr12_+_15956585 0.69 ENST00000526530.1
deoxyribose-phosphate aldolase
chr6_-_53510445 0.67 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr19_+_53962925 0.66 ENST00000270458.4
calcium voltage-gated channel auxiliary subunit gamma 8
chr10_+_102854251 0.66 ENST00000339834.10
ENST00000369883.3
BLOC-1 related complex subunit 7
chrX_-_139642835 0.65 ENST00000536274.5
MCF.2 cell line derived transforming sequence
chr2_-_208189985 0.64 ENST00000449053.1
chromosome 2 open reading frame 80
chr20_+_31514410 0.63 ENST00000335574.10
ENST00000340852.9
ENST00000398174.9
ENST00000466766.2
ENST00000498035.5
ENST00000344042.5
histocompatibility minor 13
chr7_+_134527560 0.62 ENST00000359579.5
aldo-keto reductase family 1 member B10
chr17_+_39626702 0.62 ENST00000580825.5
protein phosphatase 1 regulatory inhibitor subunit 1B
chr1_+_59310071 0.61 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr14_-_80231052 0.59 ENST00000557010.5
iodothyronine deiodinase 2
chr10_-_77637721 0.59 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chr6_-_52994248 0.58 ENST00000457564.1
ENST00000370960.5
glutathione S-transferase alpha 4
chr10_+_133394119 0.57 ENST00000317502.11
ENST00000432508.3
mitochondrial ribosome associated GTPase 1
chr17_-_58415628 0.55 ENST00000583753.5
ring finger protein 43
chr10_+_5048748 0.54 ENST00000602997.5
ENST00000439082.7
aldo-keto reductase family 1 member C3
chr2_-_182242031 0.54 ENST00000358139.6
phosphodiesterase 1A
chr11_+_99021066 0.53 ENST00000527185.5
ENST00000528682.5
contactin 5
chr3_+_40100007 0.53 ENST00000539167.2
myosin VIIA and Rab interacting protein
chr11_-_7677222 0.52 ENST00000524608.5
cytochrome b5 reductase 2
chr12_+_109052564 0.51 ENST00000257548.10
ENST00000536723.5
ENST00000536393.5
ubiquitin specific peptidase 30
chr10_-_126670686 0.51 ENST00000488181.3
chromosome 10 open reading frame 90
chr7_-_22194709 0.51 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr9_-_4666347 0.51 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr17_-_52158678 0.51 ENST00000451037.7
carbonic anhydrase 10
chr10_-_22003678 0.50 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr1_-_95072936 0.50 ENST00000370205.6
ALG14 UDP-N-acetylglucosaminyltransferase subunit
chr7_+_151028422 0.50 ENST00000542328.5
ENST00000461373.5
ENST00000297504.10
ENST00000358849.9
ENST00000498578.5
ENST00000477719.5
ENST00000477092.5
ATP binding cassette subfamily B member 8
chr11_+_73647701 0.48 ENST00000543524.5
pleckstrin homology domain containing B1
chr11_+_22674769 0.48 ENST00000532398.1
growth arrest specific 2
chr11_+_99020940 0.47 ENST00000524871.6
contactin 5
chrX_-_72877864 0.47 ENST00000596389.5
DMRT like family C1
chr22_+_41381923 0.46 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr19_-_50637939 0.46 ENST00000338916.8
synaptotagmin 3
chr1_+_107141022 0.45 ENST00000370067.5
ENST00000370068.6
netrin G1
chr8_-_61646807 0.44 ENST00000522919.5
aspartate beta-hydroxylase
chr5_+_126462339 0.44 ENST00000502348.5
GRAM domain containing 2B
chr10_+_133394094 0.44 ENST00000477902.6
mitochondrial ribosome associated GTPase 1
chr6_+_125919210 0.43 ENST00000438495.6
nuclear receptor coactivator 7
chr18_-_72638510 0.43 ENST00000581073.1
cerebellin 2 precursor
chr4_-_99352730 0.43 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr10_-_126521439 0.42 ENST00000284694.11
ENST00000432642.5
chromosome 10 open reading frame 90
chr5_-_11589019 0.42 ENST00000511377.5
catenin delta 2
chr8_-_109974688 0.42 ENST00000297404.1
potassium voltage-gated channel modifier subfamily V member 1
chr20_-_35284745 0.40 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr6_+_125781108 0.39 ENST00000368357.7
nuclear receptor coactivator 7
chr5_-_11588842 0.38 ENST00000503622.5
catenin delta 2
chr8_-_61689768 0.38 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
aspartate beta-hydroxylase
chr8_-_61646863 0.37 ENST00000519678.5
aspartate beta-hydroxylase
chr5_-_11588796 0.37 ENST00000513598.5
catenin delta 2
chr11_-_26572102 0.36 ENST00000455601.6
mucin 15, cell surface associated
chr4_+_140343443 0.35 ENST00000338517.8
ENST00000394203.7
ENST00000506322.5
short coiled-coil protein
chr11_+_73647549 0.35 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr5_+_141387698 0.34 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr6_-_127518875 0.34 ENST00000465909.2
ENST00000467753.1
SOGA family member 3
chr3_-_58627567 0.34 ENST00000649301.1
family with sequence similarity 107 member A
chr8_+_91249307 0.32 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr11_-_83682385 0.32 ENST00000426717.6
discs large MAGUK scaffold protein 2
chr22_+_17369420 0.32 ENST00000262608.13
ENST00000342247.10
CECR2 histone acetyl-lysine reader
chr2_+_186694007 0.32 ENST00000304698.10
family with sequence similarity 171 member B
chr5_+_140360187 0.31 ENST00000506757.7
ENST00000506545.5
ENST00000432095.6
ENST00000507527.1
solute carrier family 4 member 9
chr1_+_160367061 0.31 ENST00000302101.6
nescient helix-loop-helix 1
chr6_-_127519191 0.31 ENST00000525778.5
SOGA family member 3
chr10_-_77637902 0.31 ENST00000286627.10
ENST00000639486.1
ENST00000640523.1
potassium calcium-activated channel subfamily M alpha 1
chr7_-_14841267 0.30 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr6_+_30888730 0.28 ENST00000376575.7
ENST00000513240.5
discoidin domain receptor tyrosine kinase 1
chr6_+_30888672 0.28 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr11_-_89065945 0.28 ENST00000393294.3
glutamate metabotropic receptor 5
chrX_-_103688090 0.28 ENST00000433176.6
mortality factor 4 like 2
chr19_+_55857437 0.28 ENST00000587891.5
NLR family pyrin domain containing 4
chr3_-_74521140 0.27 ENST00000263665.6
contactin 3
chr2_+_184598520 0.27 ENST00000302277.7
zinc finger protein 804A
chr19_-_46077093 0.27 ENST00000601672.5
IGF like family member 4
chr18_+_63949279 0.27 ENST00000408945.5
histocompatibility minor serpin domain containing
chr20_+_59300703 0.26 ENST00000395654.3
endothelin 3
chr13_+_45464901 0.26 ENST00000349995.10
component of oligomeric golgi complex 3
chr10_-_72523936 0.26 ENST00000398763.8
ENST00000418483.6
ENST00000489666.2
mitochondrial calcium uptake 1
chr7_-_14974773 0.25 ENST00000437998.1
diacylglycerol kinase beta
chrX_-_135764444 0.25 ENST00000597510.6
cancer/testis antigen family 45 member A3
chr1_-_155244645 0.24 ENST00000327247.9
glucosylceramidase beta
chr19_+_21020675 0.24 ENST00000595401.1
zinc finger protein 430
chr12_-_23584600 0.23 ENST00000396007.6
SRY-box transcription factor 5
chr6_+_30888744 0.23 ENST00000424544.2
discoidin domain receptor tyrosine kinase 1
chr10_-_11532275 0.22 ENST00000277575.5
USP6 N-terminal like
chr7_-_100827504 0.22 ENST00000616502.4
ENST00000358173.8
EPH receptor B4
chrX_-_143517473 0.22 ENST00000370503.2
SPANX family member N3
chr1_-_155244684 0.22 ENST00000428024.3
glucosylceramidase beta
chr16_-_70801131 0.22 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr16_+_569931 0.22 ENST00000439574.1
ENST00000321878.10
ENST00000422307.6
ENST00000026218.9
ENST00000470411.2
phosphatidylinositol glycan anchor biosynthesis class Q
chr13_+_113044632 0.21 ENST00000397021.5
MCF.2 cell line derived transforming sequence like
chr11_-_26572130 0.20 ENST00000527569.1
mucin 15, cell surface associated
chr1_-_154608140 0.20 ENST00000529168.2
ENST00000368474.9
ENST00000680305.1
ENST00000648231.2
adenosine deaminase RNA specific
chr19_+_20776292 0.20 ENST00000360204.5
ENST00000344519.10
ENST00000594534.5
zinc finger protein 66
chr4_-_121164314 0.20 ENST00000057513.8
TNFAIP3 interacting protein 3
chr11_-_83682414 0.20 ENST00000404783.7
discs large MAGUK scaffold protein 2
chr17_-_51046868 0.19 ENST00000510283.5
ENST00000510855.1
sperm associated antigen 9
chr11_+_56103687 0.18 ENST00000313503.2
ENST00000641311.1
olfactory receptor family 8 subfamily H member 2
chrX_-_66033664 0.18 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr20_+_59300589 0.16 ENST00000337938.7
ENST00000371025.7
endothelin 3
chr19_-_38912177 0.15 ENST00000571838.2
coiled-coil glutamate rich protein 2
chr11_-_57324907 0.15 ENST00000358252.8
tankyrase 1 binding protein 1
chr1_+_205227889 0.15 ENST00000358024.8
transmembrane and coiled-coil domain family 2
chr6_-_161274042 0.15 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_+_8318088 0.14 ENST00000471889.7
solute carrier family 45 member 1
chr9_-_104599413 0.14 ENST00000374779.3
olfactory receptor family 13 subfamily C member 5
chr16_-_75701459 0.14 ENST00000633875.4
double homeobox B
chr9_-_34458533 0.14 ENST00000379089.5
ENST00000379087.5
ENST00000379084.5
ENST00000379081.5
ENST00000379080.5
ENST00000422409.5
ENST00000379078.1
ENST00000651358.1
ENST00000445726.5
ENST00000297620.8
family with sequence similarity 219 member A
chr16_-_67183948 0.13 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr1_-_53838276 0.13 ENST00000371429.4
NDC1 transmembrane nucleoporin
chr22_+_23762990 0.12 ENST00000402217.8
chromosome 22 open reading frame 15
chr18_+_31447732 0.12 ENST00000257189.5
desmoglein 3
chr17_-_38967393 0.12 ENST00000378079.3
F-box protein 47
chr9_-_92536031 0.12 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr10_+_88664439 0.12 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr11_-_4368386 0.12 ENST00000624801.3
olfactory receptor family 52 subfamily B member 4
chr13_+_113044714 0.12 ENST00000423251.1
MCF.2 cell line derived transforming sequence like
chr2_+_196713117 0.12 ENST00000409270.5
coiled-coil domain containing 150
chr11_-_559377 0.12 ENST00000486629.1
lamin tail domain containing 2
chr4_+_158315309 0.11 ENST00000460056.6
relaxin family peptide receptor 1
chr20_+_31968141 0.11 ENST00000562532.3
XK related 7
chr3_+_159069252 0.11 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1 readthrough
chr4_+_145680146 0.11 ENST00000438731.7
chromosome 4 open reading frame 51
chr6_-_161274010 0.11 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_+_76074698 0.11 ENST00000328299.4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr14_-_54441325 0.10 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr21_+_38809596 0.10 ENST00000456966.1
ETS proto-oncogene 2, transcription factor

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.7 3.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 1.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 1.2 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.4 1.5 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.4 2.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 5.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.8 GO:0001757 somite specification(GO:0001757)
0.3 3.0 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 1.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.9 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 2.3 GO:0051005 negative regulation of phospholipase activity(GO:0010519) negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 6.0 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 1.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 3.7 GO:0006069 ethanol oxidation(GO:0006069)
0.2 2.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 2.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 2.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.2 1.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.8 GO:0033058 directional locomotion(GO:0033058)
0.2 0.5 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.7 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 2.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.7 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 1.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 2.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 1.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.8 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 1.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 4.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 3.9 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 1.0 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 7.0 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.0 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.6 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 3.9 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.6 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 3.3 GO:0021549 cerebellum development(GO:0021549)
0.0 0.8 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0098722 asymmetric neuroblast division(GO:0055059) asymmetric stem cell division(GO:0098722)
0.0 0.7 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 2.2 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 3.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0005579 membrane attack complex(GO:0005579)
0.2 4.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 3.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 3.3 GO:0010369 chromocenter(GO:0010369)
0.1 5.4 GO:0030673 axolemma(GO:0030673)
0.1 1.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 13.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.1 GO:0000795 synaptonemal complex(GO:0000795)
0.0 1.0 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 6.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 5.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005816 spindle pole body(GO:0005816)
0.0 0.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:1902271 D3 vitamins binding(GO:1902271)
0.6 2.5 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 1.6 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.5 2.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 3.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.4 2.0 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 1.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.4 5.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 0.9 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.3 1.2 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.3 6.7 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.7 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 8.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.8 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.2 1.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.5 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.2 1.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.6 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.1 0.7 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 1.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.3 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 3.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.6 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 2.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 2.5 GO:0008009 chemokine activity(GO:0008009)
0.0 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 3.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 6.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 4.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 3.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 6.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 5.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 4.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 2.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins