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Illumina Body Map 2 (GSE30611)

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Results for POU4F2

Z-value: 0.95

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Transcription factors associated with POU4F2

Gene Symbol Gene ID Gene Info
ENSG00000151615.3 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F2hg38_v1_chr4_+_146638890_146638894-0.048.2e-01Click!

Activity profile of POU4F2 motif

Sorted Z-values of POU4F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_72088533 4.32 ENST00000373109.7
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr10_-_72088504 3.76 ENST00000536168.2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr14_+_21887848 3.44 ENST00000390437.2
T cell receptor alpha variable 12-2
chr1_+_198638968 2.81 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr9_+_122371014 2.69 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr11_+_31650024 2.68 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr3_+_108822778 2.61 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr11_+_118304721 2.57 ENST00000361763.9
CD3e molecule
chr2_-_157444044 2.56 ENST00000264192.8
cytohesin 1 interacting protein
chr3_+_108822759 2.51 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr9_+_122371036 2.47 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr1_+_198638457 2.43 ENST00000367379.6
protein tyrosine phosphatase receptor type C
chr7_-_81770039 2.39 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
hepatocyte growth factor
chr12_-_89352395 2.38 ENST00000308385.6
dual specificity phosphatase 6
chr9_+_122370523 2.33 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr12_-_89352487 2.31 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr1_+_198638723 2.25 ENST00000643513.1
protein tyrosine phosphatase receptor type C
chr14_+_22422371 2.10 ENST00000390469.2
T cell receptor delta variable 2
chr3_+_122055355 1.92 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr1_+_198639162 1.88 ENST00000418674.1
protein tyrosine phosphatase receptor type C
chr17_-_10026265 1.63 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr6_-_110815152 1.44 ENST00000413605.6
cyclin dependent kinase 19
chr11_-_31509569 1.36 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chr7_-_81770122 1.30 ENST00000423064.7
hepatocyte growth factor
chr6_-_110815096 1.26 ENST00000457688.5
cyclin dependent kinase 19
chr14_+_22096017 1.23 ENST00000390452.2
T cell receptor delta variable 1
chr16_+_28494634 1.22 ENST00000564831.6
ENST00000431282.2
apolipoprotein B receptor
chr6_-_110815408 1.20 ENST00000368911.8
cyclin dependent kinase 19
chr1_+_40040720 1.18 ENST00000414893.5
ENST00000372792.7
ENST00000372805.8
ENST00000414281.5
ENST00000420216.5
ENST00000372798.5
ENST00000340450.7
ENST00000435719.5
ENST00000427843.5
ENST00000417287.5
ENST00000424977.1
cyclase associated actin cytoskeleton regulatory protein 1
chr18_-_28036585 1.10 ENST00000399380.7
cadherin 2
chr17_-_81656532 1.08 ENST00000331056.10
phosphodiesterase 6G
chr2_+_190927649 1.06 ENST00000409428.5
ENST00000409215.5
glutaminase
chr4_-_36243939 1.04 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_40040788 1.02 ENST00000446031.1
cyclase associated actin cytoskeleton regulatory protein 1
chr1_+_50108856 0.98 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr6_+_10521337 0.94 ENST00000495262.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr6_+_12717660 0.93 ENST00000674637.1
phosphatase and actin regulator 1
chr1_+_40040583 0.87 ENST00000421589.5
cyclase associated actin cytoskeleton regulatory protein 1
chr11_+_73787853 0.85 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr2_+_17816458 0.84 ENST00000281047.4
mesogenin 1
chr11_-_107858777 0.83 ENST00000525815.6
solute carrier family 35 member F2
chr5_-_141619049 0.76 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr14_+_94026314 0.75 ENST00000203664.10
ENST00000553723.1
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr4_-_168480477 0.74 ENST00000514748.5
ENST00000512371.1
ENST00000505890.5
ENST00000682922.1
ENST00000511577.5
DExD/H-box 60 like
chr13_+_45464901 0.72 ENST00000349995.10
component of oligomeric golgi complex 3
chr1_+_66354375 0.70 ENST00000480109.2
phosphodiesterase 4B
chr3_-_11568764 0.64 ENST00000424529.6
vestigial like family member 4
chrX_-_134797134 0.63 ENST00000370790.5
ENST00000493333.5
ENST00000611027.2
ENST00000343004.10
ENST00000298090.10
PABIR family member 2
chr2_+_44275457 0.61 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr2_-_69643152 0.59 ENST00000606389.7
AP2 associated kinase 1
chr8_-_48921735 0.57 ENST00000396822.6
snail family transcriptional repressor 2
chr17_-_40799939 0.56 ENST00000306658.8
keratin 28
chr19_-_35812838 0.54 ENST00000653904.2
proline dehydrogenase 2
chr8_-_18683932 0.53 ENST00000615573.4
pleckstrin and Sec7 domain containing 3
chr2_+_171453122 0.53 ENST00000611110.4
ENST00000339506.7
DDB1 and CUL4 associated factor 17
chr4_+_158521714 0.53 ENST00000613319.4
ENST00000423548.5
ENST00000448688.6
relaxin family peptide receptor 1
chr6_+_106461464 0.52 ENST00000651520.1
crystallin beta-gamma domain containing 1
chr17_+_74935892 0.52 ENST00000328801.6
otopetrin 3
chr8_-_18684093 0.52 ENST00000428502.6
pleckstrin and Sec7 domain containing 3
chr12_-_118359105 0.51 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr2_+_44275491 0.51 ENST00000410056.7
ENST00000409741.5
ENST00000409229.7
solute carrier family 3 member 1
chrX_-_40096190 0.51 ENST00000679513.1
BCL6 corepressor
chr19_+_45498439 0.50 ENST00000451287.7
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr4_+_168497113 0.50 ENST00000511948.1
palladin, cytoskeletal associated protein
chr12_+_53954870 0.49 ENST00000243103.4
homeobox C12
chr19_-_7633713 0.48 ENST00000311069.6
Purkinje cell protein 2
chr7_-_81769971 0.47 ENST00000354224.10
ENST00000643024.1
hepatocyte growth factor
chr20_+_6007245 0.47 ENST00000378868.4
cardiolipin synthase 1
chr5_-_141618957 0.46 ENST00000389054.8
diaphanous related formin 1
chr2_-_70553440 0.45 ENST00000450929.5
transforming growth factor alpha
chr11_+_72114840 0.44 ENST00000622388.4
folate receptor gamma
chr11_-_107858561 0.43 ENST00000375682.8
solute carrier family 35 member F2
chr4_+_158521872 0.40 ENST00000307765.10
relaxin family peptide receptor 1
chr6_-_25874212 0.40 ENST00000361703.10
ENST00000397060.8
solute carrier family 17 member 3
chr17_+_75543258 0.39 ENST00000581713.5
LLGL scribble cell polarity complex component 2
chr8_-_18684033 0.39 ENST00000614430.3
pleckstrin and Sec7 domain containing 3
chr12_+_56116623 0.39 ENST00000546591.6
ribosomal protein L41
chr6_-_73521783 0.39 ENST00000331523.7
ENST00000356303.7
eukaryotic translation elongation factor 1 alpha 1
chr5_+_135579193 0.37 ENST00000646290.1
solute carrier family 25 member 48
chr6_+_130018565 0.36 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr2_+_44275473 0.34 ENST00000260649.11
solute carrier family 3 member 1
chr1_-_182672232 0.34 ENST00000508450.5
regulator of G protein signaling 8
chr12_+_56116584 0.32 ENST00000501597.3
ribosomal protein L41
chr1_-_182671853 0.31 ENST00000367556.5
regulator of G protein signaling 8
chr4_+_158521937 0.30 ENST00000343542.9
ENST00000470033.2
relaxin family peptide receptor 1
chr4_-_122621011 0.30 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr12_-_52385649 0.28 ENST00000257951.3
keratin 84
chr7_-_81770013 0.28 ENST00000465234.2
hepatocyte growth factor
chr8_-_48921419 0.27 ENST00000020945.4
snail family transcriptional repressor 2
chr10_+_18260715 0.27 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr10_+_97584347 0.26 ENST00000370649.3
ENST00000370646.9
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr12_-_30735014 0.25 ENST00000433722.6
caprin family member 2
chr2_-_49973939 0.21 ENST00000630656.1
neurexin 1
chr11_-_96343170 0.21 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr11_-_31509588 0.19 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
inner mitochondrial membrane peptidase subunit 1
chr5_-_141618914 0.18 ENST00000518047.5
diaphanous related formin 1
chrX_+_134796758 0.18 ENST00000414371.6
PABIR family member 3
chr15_+_45252228 0.18 ENST00000560438.5
ENST00000347644.8
solute carrier family 28 member 2
chr12_+_53454718 0.17 ENST00000552819.5
ENST00000455667.7
poly(rC) binding protein 2
chr6_-_138987640 0.16 ENST00000529597.5
ENST00000415951.6
ENST00000367663.8
ENST00000409812.6
RALBP1 associated Eps domain containing 1
chr1_+_193059587 0.16 ENST00000400968.7
ENST00000415442.2
ENST00000506303.1
Ro60, Y RNA binding protein
chr12_+_64405046 0.16 ENST00000540203.5
exportin for tRNA
chrX_+_69616067 0.15 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
ectodysplasin A
chr1_+_193059448 0.15 ENST00000432079.5
Ro60, Y RNA binding protein
chr1_-_193059489 0.14 ENST00000367455.8
ENST00000421683.1
ubiquitin C-terminal hydrolase L5
chr12_-_118359166 0.13 ENST00000542902.5
TAO kinase 3
chr9_+_74615582 0.13 ENST00000396204.2
RAR related orphan receptor B
chr6_-_111483700 0.13 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr4_-_175812236 0.13 ENST00000505375.5
glycoprotein M6A
chr1_-_182671902 0.12 ENST00000483095.6
regulator of G protein signaling 8
chr6_-_89217339 0.11 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr12_+_53454764 0.10 ENST00000439930.7
ENST00000548933.5
poly(rC) binding protein 2
chr1_-_44017296 0.10 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
solute carrier family 6 member 9
chr16_-_77431553 0.09 ENST00000562345.1
ADAM metallopeptidase with thrombospondin type 1 motif 18
chr15_-_34583592 0.09 ENST00000683415.1
golgin A8 family member B
chr5_-_58999885 0.08 ENST00000317118.12
phosphodiesterase 4D
chr12_-_118359639 0.08 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr1_-_193059296 0.07 ENST00000367450.7
ENST00000367451.8
ENST00000367454.6
ENST00000367448.5
ENST00000367449.5
ubiquitin C-terminal hydrolase L5
chr19_-_7632971 0.06 ENST00000598935.5
Purkinje cell protein 2
chr7_-_42152444 0.06 ENST00000479210.1
GLI family zinc finger 3
chr5_+_67004618 0.06 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr17_-_41467386 0.05 ENST00000225899.4
keratin 32
chr10_+_93612532 0.04 ENST00000371447.4
phosphodiesterase 6C
chr12_+_78977785 0.04 ENST00000551304.5
synaptotagmin 1
chr1_-_244862381 0.03 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U
chr14_-_70416973 0.02 ENST00000555276.5
ENST00000617124.4
cytochrome c oxidase assembly factor COX16
SYNJ2BP-COX16 readthrough
chr4_+_143433491 0.01 ENST00000512843.1
GRB2 associated binding protein 1
chr1_-_31919093 0.01 ENST00000602683.5
ENST00000470404.5
protein tyrosine phosphatase 4A2

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.9 4.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.7 5.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 1.9 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.5 2.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 4.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 8.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 7.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.5 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.5 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 1.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0007379 segment specification(GO:0007379)
0.0 1.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 4.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 2.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 5.1 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.5 GO:0016592 mediator complex(GO:0016592)
0.1 7.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 11.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 8.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 4.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 9.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 5.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 1.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 2.6 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 4.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 3.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 13.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 4.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 5.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 4.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 5.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 4.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 7.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events