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Illumina Body Map 2 (GSE30611)

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Results for POU4F2

Z-value: 0.95

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Transcription factors associated with POU4F2

Gene Symbol Gene ID Gene Info
POU4F2
ENSG00000151615.3 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F2hg38_v1_chr4_+_146638890_146638894-0.048.2e-01Click!

Activity profile of POU4F2 motif

Sorted Z-values of POU4F2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_72088533 4.32 ENST00000373109.7
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr10_-_72088504 3.76 ENST00000536168.2
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr14_+_21887848 3.44 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr1_+_198638968 2.81 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
PTPRC
protein tyrosine phosphatase receptor type C
chr9_+_122371014 2.69 ENST00000362012.7
PTGS1
prostaglandin-endoperoxide synthase 1
chr11_+_31650024 2.68 ENST00000638317.1
ELP4
elongator acetyltransferase complex subunit 4
chr3_+_108822778 2.61 ENST00000295756.11
TRAT1
T cell receptor associated transmembrane adaptor 1
chr11_+_118304721 2.57 ENST00000361763.9
CD3E
CD3e molecule
chr2_-_157444044 2.56 ENST00000264192.8
CYTIP
cytohesin 1 interacting protein
chr3_+_108822759 2.51 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr9_+_122371036 2.47 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
PTGS1
prostaglandin-endoperoxide synthase 1
chr1_+_198638457 2.43 ENST00000367379.6
PTPRC
protein tyrosine phosphatase receptor type C
chr7_-_81770039 2.39 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr12_-_89352395 2.38 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr9_+_122370523 2.33 ENST00000643810.1
ENST00000540753.6
PTGS1
prostaglandin-endoperoxide synthase 1
chr12_-_89352487 2.31 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr1_+_198638723 2.25 ENST00000643513.1
PTPRC
protein tyrosine phosphatase receptor type C
chr14_+_22422371 2.10 ENST00000390469.2
TRDV2
T cell receptor delta variable 2
chr3_+_122055355 1.92 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr1_+_198639162 1.88 ENST00000418674.1
PTPRC
protein tyrosine phosphatase receptor type C
chr17_-_10026265 1.63 ENST00000437099.6
ENST00000396115.6
GAS7
growth arrest specific 7
chr6_-_110815152 1.44 ENST00000413605.6
CDK19
cyclin dependent kinase 19
chr11_-_31509569 1.36 ENST00000526776.5
IMMP1L
inner mitochondrial membrane peptidase subunit 1
chr7_-_81770122 1.30 ENST00000423064.7
HGF
hepatocyte growth factor
chr6_-_110815096 1.26 ENST00000457688.5
CDK19
cyclin dependent kinase 19
chr14_+_22096017 1.23 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr16_+_28494634 1.22 ENST00000564831.6
ENST00000431282.2
APOBR
apolipoprotein B receptor
chr6_-_110815408 1.20 ENST00000368911.8
CDK19
cyclin dependent kinase 19
chr1_+_40040720 1.18 ENST00000414893.5
ENST00000372792.7
ENST00000372805.8
ENST00000414281.5
ENST00000420216.5
ENST00000372798.5
ENST00000340450.7
ENST00000435719.5
ENST00000427843.5
ENST00000417287.5
ENST00000424977.1
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
chr18_-_28036585 1.10 ENST00000399380.7
CDH2
cadherin 2
chr17_-_81656532 1.08 ENST00000331056.10
PDE6G
phosphodiesterase 6G
chr2_+_190927649 1.06 ENST00000409428.5
ENST00000409215.5
GLS
glutaminase
chr4_-_36243939 1.04 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_40040788 1.02 ENST00000446031.1
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
chr1_+_50108856 0.98 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAVL4
ELAV like RNA binding protein 4
chr6_+_10521337 0.94 ENST00000495262.7
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr6_+_12717660 0.93 ENST00000674637.1
PHACTR1
phosphatase and actin regulator 1
chr1_+_40040583 0.87 ENST00000421589.5
CAP1
cyclase associated actin cytoskeleton regulatory protein 1
chr11_+_73787853 0.85 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
MRPL48
mitochondrial ribosomal protein L48
chr2_+_17816458 0.84 ENST00000281047.4
MSGN1
mesogenin 1
chr11_-_107858777 0.83 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr5_-_141619049 0.76 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
DIAPH1
diaphanous related formin 1
chr14_+_94026314 0.75 ENST00000203664.10
ENST00000553723.1
OTUB2
OTU deubiquitinase, ubiquitin aldehyde binding 2
chr4_-_168480477 0.74 ENST00000514748.5
ENST00000512371.1
ENST00000505890.5
ENST00000682922.1
ENST00000511577.5
DDX60L
DExD/H-box 60 like
chr13_+_45464901 0.72 ENST00000349995.10
COG3
component of oligomeric golgi complex 3
chr1_+_66354375 0.70 ENST00000480109.2
PDE4B
phosphodiesterase 4B
chr3_-_11568764 0.64 ENST00000424529.6
VGLL4
vestigial like family member 4
chrX_-_134797134 0.63 ENST00000370790.5
ENST00000493333.5
ENST00000611027.2
ENST00000343004.10
ENST00000298090.10
PABIR2
PABIR family member 2
chr2_+_44275457 0.61 ENST00000611973.4
ENST00000409387.5
SLC3A1
solute carrier family 3 member 1
chr2_-_69643152 0.59 ENST00000606389.7
AAK1
AP2 associated kinase 1
chr8_-_48921735 0.57 ENST00000396822.6
SNAI2
snail family transcriptional repressor 2
chr17_-_40799939 0.56 ENST00000306658.8
KRT28
keratin 28
chr19_-_35812838 0.54 ENST00000653904.2
PRODH2
proline dehydrogenase 2
chr8_-_18683932 0.53 ENST00000615573.4
PSD3
pleckstrin and Sec7 domain containing 3
chr2_+_171453122 0.53 ENST00000611110.4
ENST00000339506.7
DCAF17
DDB1 and CUL4 associated factor 17
chr4_+_158521714 0.53 ENST00000613319.4
ENST00000423548.5
ENST00000448688.6
RXFP1
relaxin family peptide receptor 1
chr6_+_106461464 0.52 ENST00000651520.1
CRYBG1
crystallin beta-gamma domain containing 1
chr17_+_74935892 0.52 ENST00000328801.6
OTOP3
otopetrin 3
chr8_-_18684093 0.52 ENST00000428502.6
PSD3
pleckstrin and Sec7 domain containing 3
chr12_-_118359105 0.51 ENST00000541186.5
ENST00000539872.5
TAOK3
TAO kinase 3
chr2_+_44275491 0.51 ENST00000410056.7
ENST00000409741.5
ENST00000409229.7
SLC3A1
solute carrier family 3 member 1
chrX_-_40096190 0.51 ENST00000679513.1
BCOR
BCL6 corepressor
chr19_+_45498439 0.50 ENST00000451287.7
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr4_+_168497113 0.50 ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chr12_+_53954870 0.49 ENST00000243103.4
HOXC12
homeobox C12
chr19_-_7633713 0.48 ENST00000311069.6
PCP2
Purkinje cell protein 2
chr7_-_81769971 0.47 ENST00000354224.10
ENST00000643024.1
HGF
hepatocyte growth factor
chr20_+_6007245 0.47 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr5_-_141618957 0.46 ENST00000389054.8
DIAPH1
diaphanous related formin 1
chr2_-_70553440 0.45 ENST00000450929.5
TGFA
transforming growth factor alpha
chr11_+_72114840 0.44 ENST00000622388.4
FOLR3
folate receptor gamma
chr11_-_107858561 0.43 ENST00000375682.8
SLC35F2
solute carrier family 35 member F2
chr4_+_158521872 0.40 ENST00000307765.10
RXFP1
relaxin family peptide receptor 1
chr6_-_25874212 0.40 ENST00000361703.10
ENST00000397060.8
SLC17A3
solute carrier family 17 member 3
chr17_+_75543258 0.39 ENST00000581713.5
LLGL2
LLGL scribble cell polarity complex component 2
chr8_-_18684033 0.39 ENST00000614430.3
PSD3
pleckstrin and Sec7 domain containing 3
chr12_+_56116623 0.39 ENST00000546591.6
RPL41
ribosomal protein L41
chr6_-_73521783 0.39 ENST00000331523.7
ENST00000356303.7
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr5_+_135579193 0.37 ENST00000646290.1
SLC25A48
solute carrier family 25 member 48
chr6_+_130018565 0.36 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr2_+_44275473 0.34 ENST00000260649.11
SLC3A1
solute carrier family 3 member 1
chr1_-_182672232 0.34 ENST00000508450.5
RGS8
regulator of G protein signaling 8
chr12_+_56116584 0.32 ENST00000501597.3
RPL41
ribosomal protein L41
chr1_-_182671853 0.31 ENST00000367556.5
RGS8
regulator of G protein signaling 8
chr4_+_158521937 0.30 ENST00000343542.9
ENST00000470033.2
RXFP1
relaxin family peptide receptor 1
chr4_-_122621011 0.30 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr12_-_52385649 0.28 ENST00000257951.3
KRT84
keratin 84
chr7_-_81770013 0.28 ENST00000465234.2
HGF
hepatocyte growth factor
chr8_-_48921419 0.27 ENST00000020945.4
SNAI2
snail family transcriptional repressor 2
chr10_+_18260715 0.27 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr10_+_97584347 0.26 ENST00000370649.3
ENST00000370646.9
ENSG00000249967.1
HOGA1
novel protein
4-hydroxy-2-oxoglutarate aldolase 1
chr12_-_30735014 0.25 ENST00000433722.6
CAPRIN2
caprin family member 2
chr2_-_49973939 0.21 ENST00000630656.1
NRXN1
neurexin 1
chr11_-_96343170 0.21 ENST00000524717.6
MAML2
mastermind like transcriptional coactivator 2
chr11_-_31509588 0.19 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
IMMP1L
inner mitochondrial membrane peptidase subunit 1
chr5_-_141618914 0.18 ENST00000518047.5
DIAPH1
diaphanous related formin 1
chrX_+_134796758 0.18 ENST00000414371.6
PABIR3
PABIR family member 3
chr15_+_45252228 0.18 ENST00000560438.5
ENST00000347644.8
SLC28A2
solute carrier family 28 member 2
chr12_+_53454718 0.17 ENST00000552819.5
ENST00000455667.7
PCBP2
poly(rC) binding protein 2
chr6_-_138987640 0.16 ENST00000529597.5
ENST00000415951.6
ENST00000367663.8
ENST00000409812.6
REPS1
RALBP1 associated Eps domain containing 1
chr1_+_193059587 0.16 ENST00000400968.7
ENST00000415442.2
ENST00000506303.1
RO60
Ro60, Y RNA binding protein
chr12_+_64405046 0.16 ENST00000540203.5
XPOT
exportin for tRNA
chrX_+_69616067 0.15 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
EDA
ectodysplasin A
chr1_+_193059448 0.15 ENST00000432079.5
RO60
Ro60, Y RNA binding protein
chr1_-_193059489 0.14 ENST00000367455.8
ENST00000421683.1
UCHL5
ubiquitin C-terminal hydrolase L5
chr12_-_118359166 0.13 ENST00000542902.5
TAOK3
TAO kinase 3
chr9_+_74615582 0.13 ENST00000396204.2
RORB
RAR related orphan receptor B
chr6_-_111483700 0.13 ENST00000435970.5
ENST00000358835.7
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit
chr4_-_175812236 0.13 ENST00000505375.5
GPM6A
glycoprotein M6A
chr1_-_182671902 0.12 ENST00000483095.6
RGS8
regulator of G protein signaling 8
chr6_-_89217339 0.11 ENST00000454853.7
GABRR1
gamma-aminobutyric acid type A receptor subunit rho1
chr12_+_53454764 0.10 ENST00000439930.7
ENST00000548933.5
PCBP2
poly(rC) binding protein 2
chr1_-_44017296 0.10 ENST00000357730.6
ENST00000360584.6
ENST00000528803.1
SLC6A9
solute carrier family 6 member 9
chr16_-_77431553 0.09 ENST00000562345.1
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18
chr15_-_34583592 0.09 ENST00000683415.1
GOLGA8B
golgin A8 family member B
chr5_-_58999885 0.08 ENST00000317118.12
PDE4D
phosphodiesterase 4D
chr12_-_118359639 0.08 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAOK3
TAO kinase 3
chr1_-_193059296 0.07 ENST00000367450.7
ENST00000367451.8
ENST00000367454.6
ENST00000367448.5
ENST00000367449.5
UCHL5
ubiquitin C-terminal hydrolase L5
chr19_-_7632971 0.06 ENST00000598935.5
PCP2
Purkinje cell protein 2
chr7_-_42152444 0.06 ENST00000479210.1
GLI3
GLI family zinc finger 3
chr5_+_67004618 0.06 ENST00000261569.11
ENST00000436277.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr17_-_41467386 0.05 ENST00000225899.4
KRT32
keratin 32
chr10_+_93612532 0.04 ENST00000371447.4
PDE6C
phosphodiesterase 6C
chr12_+_78977785 0.04 ENST00000551304.5
SYT1
synaptotagmin 1
chr1_-_244862381 0.03 ENST00000640001.1
ENST00000639628.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr14_-_70416973 0.02 ENST00000555276.5
ENST00000617124.4
COX16
SYNJ2BP-COX16
cytochrome c oxidase assembly factor COX16
SYNJ2BP-COX16 readthrough
chr4_+_143433491 0.01 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr1_-_31919093 0.01 ENST00000602683.5
ENST00000470404.5
PTP4A2
protein tyrosine phosphatase 4A2

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.4 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.9 4.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.7 5.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 1.9 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.5 2.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 4.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4 8.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 7.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 1.5 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.9 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.5 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 1.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0007379 segment specification(GO:0007379)
0.0 1.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 4.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 2.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 5.1 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.5 GO:0016592 mediator complex(GO:0016592)
0.1 7.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 11.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 8.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 4.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 2.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 9.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 5.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 1.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 2.6 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 3.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 4.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 3.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 13.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 4.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 5.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 3.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 4.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 5.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 4.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 7.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events