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Illumina Body Map 2 (GSE30611)

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Results for POU5F1_POU2F3

Z-value: 4.92

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.20 POU class 5 homeobox 1
ENSG00000137709.10 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg38_v1_chr6_-_31170620_311706980.173.6e-01Click!
POU2F3hg38_v1_chr11_+_120236635_1202366420.057.7e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_22720615 38.34 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr14_-_106593319 30.13 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr22_+_22686724 28.88 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr14_-_106117159 27.44 ENST00000390601.3
immunoglobulin heavy variable 3-11
chr22_+_22409755 27.31 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr2_+_89959979 27.22 ENST00000453166.2
immunoglobulin kappa variable 2D-28
chr2_-_88947820 25.86 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr2_-_89100352 25.41 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr14_-_106277039 25.36 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr22_+_22357739 25.11 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr22_+_22758698 24.94 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr2_-_89268506 24.82 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr2_+_89913982 24.50 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr14_-_105987068 24.29 ENST00000390594.3
immunoglobulin heavy variable 1-2
chr2_-_89245596 23.87 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr14_-_106675544 23.43 ENST00000390632.2
immunoglobulin heavy variable 3-66
chr2_+_89936859 23.22 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr14_-_106154113 23.07 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr14_-_106803221 22.77 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr14_-_106715166 22.73 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr2_+_90114838 22.72 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr22_+_22195753 22.35 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr14_-_106579223 22.35 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr2_+_90100235 22.20 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chrX_-_48919015 21.70 ENST00000376509.4
Pim-2 proto-oncogene, serine/threonine kinase
chr2_-_89143133 21.45 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr2_-_89040745 21.27 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_-_89222461 21.25 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr14_-_106762576 21.11 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr2_+_90159840 20.35 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr14_-_106360320 20.29 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr22_+_22098683 20.25 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr2_+_90038848 20.02 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_-_88992903 19.65 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_22030934 19.51 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr14_-_106130061 19.50 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr2_-_89177160 19.20 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr2_+_89947508 19.15 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr14_-_106627685 19.04 ENST00000390629.3
immunoglobulin heavy variable 4-59
chr4_-_70666492 18.85 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr22_+_22792485 18.78 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr22_+_22880706 18.50 ENST00000390319.2
immunoglobulin lambda variable 3-1
chr2_+_88885397 18.36 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr14_-_106538331 18.08 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr2_+_90154073 17.77 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr14_-_106374129 17.74 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr14_-_106012390 17.18 ENST00000455737.2
immunoglobulin heavy variable 4-4
chr22_+_22431949 17.06 ENST00000390301.3
immunoglobulin lambda variable 1-36
chr22_+_22734577 16.61 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr22_+_22747383 16.50 ENST00000390311.3
immunoglobulin lambda variable 3-16
chr16_+_32066065 16.18 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr22_+_22818994 16.02 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr2_-_89320146 15.88 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr14_-_106470788 15.50 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr22_+_22668286 15.39 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr2_+_90004792 15.14 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr14_-_106108453 14.96 ENST00000632950.2
immunoglobulin heavy variable 5-10-1
chr14_-_106088573 14.68 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr2_-_89160329 14.31 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr4_-_70666961 14.19 ENST00000510437.5
joining chain of multimeric IgA and IgM
chr15_-_21742799 14.04 ENST00000622410.2
novel protein, identical to IGHV4-4
chr2_+_90082635 14.03 ENST00000483379.1
immunoglobulin kappa variable 1D-17
chr22_+_22395005 13.75 ENST00000390298.2
immunoglobulin lambda variable 7-43
chr2_+_89851723 13.65 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr22_+_22822658 13.59 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr22_+_22380766 13.37 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr2_+_89862438 13.25 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr2_+_88897230 13.18 ENST00000390244.2
immunoglobulin kappa variable 5-2
chr4_-_70666884 13.09 ENST00000510614.5
joining chain of multimeric IgA and IgM
chr14_-_106622837 12.92 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr6_-_32816910 12.91 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr14_-_106791226 12.65 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr2_-_181657096 12.62 ENST00000410087.8
ENST00000409440.7
ceramide kinase like
chr2_+_90172802 12.50 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr2_-_89117844 12.34 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr2_+_90021567 12.20 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr14_-_106335613 12.12 ENST00000603660.1
immunoglobulin heavy variable 3-30
chr2_-_89085787 11.94 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr2_-_89213917 11.92 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr22_+_22811737 11.86 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr14_-_106062670 11.78 ENST00000390598.2
immunoglobulin heavy variable 3-7
chr22_+_22697789 11.67 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr14_-_106038355 11.37 ENST00000390597.3
immunoglobulin heavy variable 2-5
chr14_-_106422175 11.37 ENST00000390619.2
immunoglobulin heavy variable 4-39
chr2_+_87338511 11.05 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr14_-_106658251 10.59 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr4_+_40192949 10.59 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chr2_+_113406368 10.34 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr2_-_88966767 10.33 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr16_+_23835946 10.32 ENST00000321728.12
ENST00000643927.1
protein kinase C beta
chr2_+_90234809 10.29 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr7_-_3043838 9.79 ENST00000356408.3
ENST00000396946.9
caspase recruitment domain family member 11
chr14_-_106811131 9.76 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr14_-_106557465 9.68 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr2_-_88857582 9.41 ENST00000390237.2
immunoglobulin kappa constant
chr14_-_106771020 9.40 ENST00000617374.2
immunoglobulin heavy variable 2-70
chr9_-_34691204 9.27 ENST00000378800.3
ENST00000311925.7
C-C motif chemokine ligand 19
chr16_+_32995048 9.24 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr14_-_106724093 9.15 ENST00000390634.3
immunoglobulin heavy variable 2-70D
chr6_-_31592992 9.13 ENST00000340027.10
natural cytotoxicity triggering receptor 3
chr2_+_89884740 9.07 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr19_-_38617912 8.99 ENST00000591517.5
mitogen-activated protein kinase kinase kinase kinase 1
chr22_-_23754376 8.95 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr19_+_14583076 8.88 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr13_-_99307387 8.88 ENST00000376414.5
G protein-coupled receptor 183
chr16_+_33827140 8.80 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr6_-_107824294 8.77 ENST00000369020.8
ENST00000369022.6
Scm polycomb group protein like 4
chr22_+_22369601 8.64 ENST00000390295.3
immunoglobulin lambda variable 7-46
chr22_+_22375984 8.60 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr22_+_22343185 8.56 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr12_-_122716790 8.44 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr7_-_142813394 8.42 ENST00000417977.2
T cell receptor beta variable 30
chr22_+_22322452 8.30 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr3_+_46354072 8.28 ENST00000445132.3
ENST00000421659.1
C-C motif chemokine receptor 2
chr14_-_106639589 8.25 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr16_+_33009175 8.23 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr14_-_106389858 8.19 ENST00000390617.2
immunoglobulin heavy variable 3-35 (non-functional)
chr14_+_21712313 8.15 ENST00000390424.2
T cell receptor alpha variable 2
chr19_-_38617928 8.15 ENST00000396857.7
ENST00000586296.5
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_88979016 8.14 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr5_+_157180816 8.03 ENST00000422843.8
IL2 inducible T cell kinase
chr4_+_70226116 8.00 ENST00000317987.6
follicular dendritic cell secreted protein
chr2_+_90209873 7.93 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr14_-_106211453 7.92 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr14_-_106301848 7.88 ENST00000390611.2
immunoglobulin heavy variable 2-26
chr22_+_22162155 7.84 ENST00000390284.2
immunoglobulin lambda variable 4-60
chr2_-_89297785 7.79 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr2_-_89010515 7.63 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr14_-_106025628 7.62 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr17_-_63932261 7.59 ENST00000349817.2
ENST00000006750.8
ENST00000392795.7
CD79b molecule
chr1_+_27342014 7.28 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr2_-_112836702 6.99 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr8_-_133102477 6.97 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr8_+_55879818 6.93 ENST00000520220.6
ENST00000519728.6
LYN proto-oncogene, Src family tyrosine kinase
chr1_+_5992639 6.86 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr21_-_10649835 6.77 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr1_-_157777124 6.68 ENST00000361516.8
ENST00000368181.4
Fc receptor like 2
chr14_-_106235582 6.60 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr14_-_106349792 6.59 ENST00000438142.3
immunoglobulin heavy variable 4-31
chr19_+_35329161 6.56 ENST00000341773.10
ENST00000600131.5
ENST00000595780.5
ENST00000597916.5
ENST00000593867.5
ENST00000600424.5
ENST00000599811.5
ENST00000536635.6
ENST00000085219.10
ENST00000544992.6
ENST00000419549.6
CD22 molecule
chr22_+_22427517 6.48 ENST00000390300.2
immunoglobulin lambda variable 5-37
chr5_-_111756245 6.38 ENST00000447165.6
neuronal regeneration related protein
chr6_-_127900958 6.34 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr6_-_31592952 6.23 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr2_+_90220727 6.18 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr17_-_75844334 6.11 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
unc-13 homolog D
chrX_-_13817027 6.11 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr19_-_18397596 5.92 ENST00000595840.1
ENST00000339007.4
leucine rich repeat containing 25
chr14_-_106165730 5.92 ENST00000390604.2
immunoglobulin heavy variable 3-16 (non-functional)
chr17_+_14301069 5.83 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr9_-_35618367 5.64 ENST00000378431.5
ENST00000378430.3
ENST00000259633.9
CD72 molecule
chr4_-_163613505 5.59 ENST00000339875.9
membrane associated ring-CH-type finger 1
chr2_+_89985922 5.53 ENST00000390268.2
immunoglobulin kappa variable 2D-26
chr1_-_157820060 5.52 ENST00000491942.1
ENST00000358292.7
Fc receptor like 1
chr6_+_35297809 5.52 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr6_+_26124161 5.48 ENST00000377791.4
ENST00000602637.1
H2A clustered histone 6
chr5_-_67196791 5.36 ENST00000256447.5
CD180 molecule
chr7_+_50308672 5.24 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr6_-_154246850 5.21 ENST00000517438.5
interaction protein for cytohesin exchange factors 1
chr8_-_133102623 5.04 ENST00000524345.5
Src like adaptor
chr14_-_106411021 5.02 ENST00000390618.2
immunoglobulin heavy variable 3-38 (non-functional)
chr6_-_27146841 4.98 ENST00000356950.2
H2B clustered histone 12
chr15_-_19988117 4.94 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr5_+_55102635 4.93 ENST00000274306.7
granzyme A
chr3_+_98531965 4.93 ENST00000284311.5
G protein-coupled receptor 15
chr11_-_64744102 4.88 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr1_+_192809031 4.85 ENST00000235382.7
regulator of G protein signaling 2
chr1_-_157820113 4.83 ENST00000368176.8
Fc receptor like 1
chr1_-_157700738 4.82 ENST00000368186.9
ENST00000496769.1
ENST00000368184.8
Fc receptor like 3
chr11_-_64744317 4.79 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr6_-_11778781 4.78 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr16_+_31355215 4.76 ENST00000562522.2
integrin subunit alpha X
chr6_+_12716801 4.76 ENST00000674595.1
phosphatase and actin regulator 1
chr16_+_31355165 4.68 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr12_-_122703346 4.67 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr4_-_89307732 4.64 ENST00000609438.2
GPRIN family member 3
chr3_+_32951636 4.64 ENST00000330953.6
C-C motif chemokine receptor 4
chr14_-_106324743 4.62 ENST00000390612.3
immunoglobulin heavy variable 4-28
chr7_-_84194781 4.59 ENST00000265362.9
semaphorin 3A
chr1_-_153390976 4.58 ENST00000368732.5
ENST00000368733.4
S100 calcium binding protein A8
chr11_-_102874974 4.57 ENST00000571244.3
matrix metallopeptidase 12
chr22_+_22771791 4.51 ENST00000390313.3
immunoglobulin lambda variable 3-12
chr1_+_206557157 4.50 ENST00000577571.5
Ras association domain family member 5
chr8_-_133102874 4.50 ENST00000395352.7
Src like adaptor
chr16_-_21652598 4.50 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr13_-_99258366 4.46 ENST00000397470.5
ENST00000397473.7
G protein-coupled receptor 18
chr11_-_47378479 4.42 ENST00000533968.1
Spi-1 proto-oncogene
chr6_-_26216673 4.41 ENST00000541790.3
H2B clustered histone 8
chr2_-_207165923 4.41 ENST00000309446.11
Kruppel like factor 7
chr11_-_47378527 4.40 ENST00000378538.8
Spi-1 proto-oncogene
chr1_-_228457855 4.38 ENST00000366695.3
H2A.W histone
chr5_-_141651376 4.37 ENST00000522783.5
ENST00000519800.1
ENST00000435817.7
FCH and double SH3 domains 1
chr16_-_88941801 4.35 ENST00000569464.5
ENST00000569443.5
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr15_-_19965101 4.33 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr4_-_38804783 4.28 ENST00000308979.7
ENST00000505940.1
ENST00000515861.5
toll like receptor 1
chr11_-_47378494 4.26 ENST00000533030.1
Spi-1 proto-oncogene
chr12_+_92702983 4.25 ENST00000344636.6
ENST00000544406.2
pleckstrin homology and RhoGEF domain containing G7
chr4_+_40192989 4.18 ENST00000508513.5
ras homolog family member H
chr19_+_21020634 4.17 ENST00000599548.5
ENST00000594110.5
ENST00000261560.10
zinc finger protein 430
chr15_-_82571741 4.17 ENST00000562833.2
ENST00000611163.4
novel protein
cytoplasmic polyadenylation element binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 1285.2 GO:0006958 complement activation, classical pathway(GO:0006958)
5.1 46.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
4.3 12.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
3.1 9.3 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
3.0 9.0 GO:0002432 granuloma formation(GO:0002432)
2.8 8.3 GO:0002436 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.6 15.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
2.5 17.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
2.3 7.0 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
2.3 7.0 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
2.3 6.9 GO:0070662 mast cell proliferation(GO:0070662)
2.0 8.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
1.9 444.6 GO:0002377 immunoglobulin production(GO:0002377)
1.9 5.6 GO:0045608 negative regulation of auditory receptor cell differentiation(GO:0045608)
1.7 5.1 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.5 10.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
1.4 4.3 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
1.2 6.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
1.1 3.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
1.1 4.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
1.0 8.9 GO:0043615 astrocyte cell migration(GO:0043615)
1.0 6.8 GO:0033029 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
1.0 12.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 7.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.9 5.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.8 2.5 GO:0002238 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.8 2.5 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.8 4.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.8 5.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.8 0.8 GO:0061346 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.8 3.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.8 4.9 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.8 2.3 GO:1990709 presynaptic active zone organization(GO:1990709)
0.8 3.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.8 2.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.7 2.9 GO:0030185 nitric oxide transport(GO:0030185)
0.7 2.1 GO:1990751 positive regulation of Schwann cell migration(GO:1900149) regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.7 2.1 GO:1901257 regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.7 6.9 GO:0070995 NADPH oxidation(GO:0070995)
0.7 7.2 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.6 0.6 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.6 2.6 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.6 9.4 GO:0001865 NK T cell differentiation(GO:0001865)
0.6 4.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.6 2.4 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.6 1.2 GO:0043309 regulation of eosinophil degranulation(GO:0043309) regulation of eosinophil activation(GO:1902566)
0.6 2.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.6 3.6 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.6 2.9 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.6 5.3 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.6 2.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.6 2.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.5 3.2 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.5 1.6 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.5 3.6 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.5 1.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.5 2.0 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.5 7.4 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.4 1.8 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.4 2.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 0.9 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 1.7 GO:0018277 protein deamination(GO:0018277)
0.4 2.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.4 2.5 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.4 7.6 GO:0043383 negative T cell selection(GO:0043383)
0.4 8.8 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.4 1.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.4 2.4 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.4 4.9 GO:0021678 third ventricle development(GO:0021678)
0.4 1.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 2.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.4 3.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.4 5.5 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.4 2.0 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.4 0.8 GO:0033084 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 2.7 GO:0060023 soft palate development(GO:0060023)
0.4 7.5 GO:0002544 chronic inflammatory response(GO:0002544)
0.4 3.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.4 1.1 GO:0061011 hepatic duct development(GO:0061011)
0.4 5.8 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.4 1.8 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.4 1.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.4 2.1 GO:0090131 mesenchyme migration(GO:0090131)
0.3 1.7 GO:0061216 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 2.0 GO:0002606 regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.3 5.7 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 18.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.3 0.9 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.3 1.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.3 7.7 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3 1.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.3 2.1 GO:0061743 motor learning(GO:0061743)
0.3 1.2 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 7.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 2.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.3 1.1 GO:0009956 radial pattern formation(GO:0009956)
0.3 1.4 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.3 10.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 5.4 GO:0038203 TORC2 signaling(GO:0038203)
0.3 4.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 0.5 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 1.6 GO:0021825 substrate-dependent cerebral cortex tangential migration(GO:0021825)
0.3 2.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 2.4 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.3 1.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 1.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566)
0.3 1.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.3 1.8 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.3 18.1 GO:0007140 male meiosis(GO:0007140)
0.2 1.5 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 6.9 GO:0015671 oxygen transport(GO:0015671)
0.2 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.2 4.7 GO:0003263 cardioblast proliferation(GO:0003263) regulation of cardioblast proliferation(GO:0003264)
0.2 1.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 0.7 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 0.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 2.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 2.7 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.2 2.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.2 1.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 2.6 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2 0.7 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.2 2.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.2 2.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.2 1.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 2.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 3.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.2 0.8 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 2.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.8 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 1.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 2.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.2 0.4 GO:0031296 B cell costimulation(GO:0031296)
0.2 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 19.0 GO:0045576 mast cell activation(GO:0045576)
0.2 4.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 4.6 GO:0002507 tolerance induction(GO:0002507)
0.2 4.0 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.2 3.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.2 0.9 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 3.5 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 3.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 1.4 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510)
0.2 0.8 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 4.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 0.7 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.7 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 18.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 1.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 1.3 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 0.8 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 3.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 2.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2 0.5 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.2 2.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 0.8 GO:2000691 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.6 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 2.0 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.6 GO:0060596 mammary placode formation(GO:0060596)
0.1 3.9 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 4.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.6 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.7 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.0 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 6.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 1.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 4.9 GO:0072678 T cell migration(GO:0072678)
0.1 2.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.9 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.1 1.9 GO:0009414 response to water deprivation(GO:0009414)
0.1 4.4 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.9 GO:0002705 positive regulation of leukocyte mediated immunity(GO:0002705)
0.1 40.9 GO:0002250 adaptive immune response(GO:0002250)
0.1 0.7 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.4 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 3.9 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 1.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.4 GO:0042756 drinking behavior(GO:0042756)
0.1 1.5 GO:0040016 embryonic cleavage(GO:0040016)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 3.1 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.1 3.8 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 1.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.1 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.1 1.4 GO:0009304 tRNA transcription(GO:0009304)
0.1 1.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 2.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.2 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.1 2.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.9 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 2.6 GO:0021781 glial cell fate commitment(GO:0021781)
0.1 11.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 2.4 GO:0035640 exploration behavior(GO:0035640)
0.1 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.4 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.4 GO:0010260 organ senescence(GO:0010260)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.7 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.1 1.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.0 GO:0003360 brainstem development(GO:0003360)
0.1 4.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 6.4 GO:0006968 cellular defense response(GO:0006968)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 1.2 GO:0097264 self proteolysis(GO:0097264)
0.1 1.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 1.2 GO:0008228 opsonization(GO:0008228)
0.1 7.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 1.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 4.5 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 3.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 3.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.7 GO:0060613 fat pad development(GO:0060613)
0.1 4.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 1.6 GO:0036035 osteoclast development(GO:0036035)
0.1 0.9 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.1 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.9 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.1 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 9.1 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 7.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0015888 thiamine transport(GO:0015888)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.4 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 3.9 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 3.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 2.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.9 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0021542 dentate gyrus development(GO:0021542)
0.0 7.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.5 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 1.0 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.9 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 1.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.5 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 8.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.3 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.8 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0015825 L-serine transport(GO:0015825)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.0 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 3.8 GO:0030098 lymphocyte differentiation(GO:0030098)
0.0 1.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.8 GO:0003407 neural retina development(GO:0003407)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.1 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 2.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.5 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 7.7 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.5 67.6 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
6.7 360.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
2.0 10.1 GO:0019814 immunoglobulin complex(GO:0019814)
1.4 299.2 GO:0072562 blood microparticle(GO:0072562)
1.2 7.0 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.1 4.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.0 6.9 GO:1990031 pinceau fiber(GO:1990031)
0.8 1.6 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.8 15.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.7 2.0 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.7 2.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5 1.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.5 2.6 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.5 3.0 GO:0097441 basilar dendrite(GO:0097441)
0.5 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.5 9.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.4 2.9 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 2.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 4.7 GO:0033269 internode region of axon(GO:0033269)
0.4 3.4 GO:0035976 AP1 complex(GO:0035976)
0.4 31.5 GO:0001772 immunological synapse(GO:0001772)
0.4 1.1 GO:0009346 citrate lyase complex(GO:0009346)
0.4 3.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 1.4 GO:0043293 apoptosome(GO:0043293)
0.3 4.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 2.3 GO:1990037 Lewy body core(GO:1990037)
0.3 5.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 2.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 1.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.3 0.8 GO:0060187 cell pole(GO:0060187)
0.3 8.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 5.4 GO:0061700 GATOR2 complex(GO:0061700)
0.3 0.8 GO:0016590 ACF complex(GO:0016590)
0.2 2.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 2.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 9.1 GO:0031528 microvillus membrane(GO:0031528)
0.2 1.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 506.2 GO:0005615 extracellular space(GO:0005615)
0.2 2.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 1.3 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.2 1.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 9.4 GO:0008305 integrin complex(GO:0008305)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 13.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 6.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 4.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 4.0 GO:0000346 transcription export complex(GO:0000346)
0.1 37.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 3.2 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.8 GO:0044327 dendritic spine head(GO:0044327)
0.1 6.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.5 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 2.6 GO:0046930 pore complex(GO:0046930)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.1 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.8 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0036128 CatSper complex(GO:0036128)
0.1 1.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.7 GO:0042629 mast cell granule(GO:0042629)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.9 GO:0043596 nuclear replication fork(GO:0043596)
0.1 5.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 0.2 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 12.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.2 GO:0001652 granular component(GO:0001652)
0.1 396.3 GO:0005576 extracellular region(GO:0005576)
0.1 0.9 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 3.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.6 GO:0016235 aggresome(GO:0016235)
0.1 4.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.0 10.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 4.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.3 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0031095 platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.0 2.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.0 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 5.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 48.8 GO:0019862 IgA binding(GO:0019862)
6.2 1703.1 GO:0003823 antigen binding(GO:0003823)
2.6 10.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
2.1 8.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.5 9.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.4 26.5 GO:0046625 sphingolipid binding(GO:0046625)
1.3 8.9 GO:0042806 fucose binding(GO:0042806)
1.3 17.6 GO:0051525 NFAT protein binding(GO:0051525)
1.1 3.2 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 4.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.9 8.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.8 2.5 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.8 5.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8 7.0 GO:0045545 syndecan binding(GO:0045545)
0.7 2.9 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.7 17.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 8.9 GO:0008142 oxysterol binding(GO:0008142)
0.6 11.8 GO:0050700 CARD domain binding(GO:0050700)
0.6 2.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 3.2 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.5 2.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.5 2.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.6 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.5 1.6 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.5 4.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 2.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.5 2.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.5 1.4 GO:0042007 interleukin-18 binding(GO:0042007)
0.5 3.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 14.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 9.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 8.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.4 12.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 3.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.4 1.1 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.4 5.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 10.9 GO:0045499 chemorepellent activity(GO:0045499)
0.3 2.8 GO:0004771 sterol esterase activity(GO:0004771)
0.3 10.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 7.0 GO:0051400 BH domain binding(GO:0051400)
0.3 1.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 1.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.3 37.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 11.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 0.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 0.9 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.3 9.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 1.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.3 3.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 2.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.3 1.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.3 0.8 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 1.4 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.3 2.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 2.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 1.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 7.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 3.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 1.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.2 2.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.6 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.0 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.2 1.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 2.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 0.9 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 1.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 6.0 GO:0005112 Notch binding(GO:0005112)
0.2 2.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 4.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 5.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.6 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 0.5 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.2 4.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 6.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 7.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0005522 profilin binding(GO:0005522)
0.1 1.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 2.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.7 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 4.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 5.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.8 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 2.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 6.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.7 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.9 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 4.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 3.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0050509 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 2.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 4.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 2.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 13.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.4 GO:0070628 proteasome binding(GO:0070628)
0.1 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.6 GO:0043422 protein kinase B binding(GO:0043422)
0.1 2.0 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 3.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.4 GO:0019956 chemokine binding(GO:0019956)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 2.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.4 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.7 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.7 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 1.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 2.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 1.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 8.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004040 amidase activity(GO:0004040)
0.0 1.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.3 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 1.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 1.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.9 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 3.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 29.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 12.8 PID IL27 PATHWAY IL27-mediated signaling events
0.3 9.1 PID IL5 PATHWAY IL5-mediated signaling events
0.3 41.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 20.6 PID BCR 5PATHWAY BCR signaling pathway
0.2 8.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 10.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 3.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 10.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 2.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 15.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 11.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.2 6.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 7.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 7.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 10.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 4.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 16.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 6.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 4.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 15.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 3.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 5.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.2 PID IFNG PATHWAY IFN-gamma pathway
0.1 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 19.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 2.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 4.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 5.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 4.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 6.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 3.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 31.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 3.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 10.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 7.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 7.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 3.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 13.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 12.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 9.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 9.8 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.2 9.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 5.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 8.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 8.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 6.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 7.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 2.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 4.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 41.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 16.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 4.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 2.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 4.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 4.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 6.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 3.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 27.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 10.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 7.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.1 4.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 5.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 9.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 2.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 6.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.6 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.9 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 5.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 2.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus