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Illumina Body Map 2 (GSE30611)

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Results for POU6F2

Z-value: 1.27

Motif logo

Transcription factors associated with POU6F2

Gene Symbol Gene ID Gene Info
ENSG00000106536.21 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F2hg38_v1_chr7_+_38977904_389780090.373.9e-02Click!

Activity profile of POU6F2 motif

Sorted Z-values of POU6F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_43656289 5.54 ENST00000338702.4
monoamine oxidase A
chr3_+_159839847 4.34 ENST00000445224.6
schwannomin interacting protein 1
chr7_-_73624492 4.29 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr14_+_32329341 4.23 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr14_+_32329256 3.60 ENST00000280979.9
A-kinase anchoring protein 6
chr10_-_20897288 3.48 ENST00000377122.9
nebulette
chr8_+_91249307 3.35 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr15_-_53733103 3.03 ENST00000559418.5
WD repeat domain 72
chr12_-_16605939 2.99 ENST00000541295.5
ENST00000535535.5
LIM domain only 3
chr10_-_121596117 2.90 ENST00000351936.11
fibroblast growth factor receptor 2
chr20_+_57561103 2.82 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr4_+_109912877 2.76 ENST00000265171.10
ENST00000509793.5
ENST00000652245.1
epidermal growth factor
chr11_+_107591077 2.75 ENST00000531234.5
ENST00000265840.12
ELMO domain containing 1
chr12_-_16606102 2.74 ENST00000537304.6
LIM domain only 3
chr11_-_27472698 2.68 ENST00000389858.4
ENST00000379214.9
leucine rich repeat containing G protein-coupled receptor 4
chr5_-_97142579 2.62 ENST00000274382.9
limb and CNS expressed 1
chr12_-_16609869 2.49 ENST00000534946.5
LIM domain only 3
chr17_-_10518536 2.42 ENST00000226207.6
myosin heavy chain 1
chr7_-_150302980 2.33 ENST00000252071.8
actin related protein 3C
chr3_-_33645433 2.19 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr2_+_44275457 2.09 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr2_+_44275473 2.08 ENST00000260649.11
solute carrier family 3 member 1
chr20_+_43558968 2.06 ENST00000647834.1
ENST00000373100.7
ENST00000648083.1
ENST00000648530.1
serum/glucocorticoid regulated kinase 2
chrX_-_13817027 2.03 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr11_-_129192198 1.96 ENST00000310343.13
Rho GTPase activating protein 32
chr12_-_102950835 1.92 ENST00000546844.1
phenylalanine hydroxylase
chr9_-_76906041 1.91 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr6_+_63521738 1.91 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr2_+_44275491 1.87 ENST00000410056.7
ENST00000409741.5
ENST00000409229.7
solute carrier family 3 member 1
chr10_-_126521439 1.77 ENST00000284694.11
ENST00000432642.5
chromosome 10 open reading frame 90
chr1_-_204359885 1.77 ENST00000414478.1
ENST00000272203.8
pleckstrin homology domain containing A6
chr17_+_39628496 1.76 ENST00000394265.5
ENST00000394267.2
protein phosphatase 1 regulatory inhibitor subunit 1B
chr11_-_129192291 1.75 ENST00000682385.1
Rho GTPase activating protein 32
chr11_-_82733850 1.74 ENST00000329203.5
family with sequence similarity 181 member B
chr3_+_111998739 1.71 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr11_-_26572254 1.65 ENST00000529533.6
mucin 15, cell surface associated
chr18_-_26549402 1.58 ENST00000408011.7
potassium channel tetramerization domain containing 1
chr7_-_13989658 1.56 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr3_+_111998915 1.55 ENST00000478951.6
transgelin 3
chr12_-_86838867 1.53 ENST00000621808.4
MGAT4 family member C
chr13_-_109786567 1.51 ENST00000375856.5
insulin receptor substrate 2
chr8_-_141002072 1.50 ENST00000517453.5
protein tyrosine kinase 2
chr3_+_111999189 1.50 ENST00000455401.6
transgelin 3
chr8_-_42541042 1.49 ENST00000518717.1
solute carrier family 20 member 2
chr5_+_126371306 1.49 ENST00000506445.5
GRAM domain containing 2B
chr3_+_189789734 1.48 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
tumor protein p63
chr9_+_106863121 1.46 ENST00000472574.1
ENST00000277225.10
zinc finger protein 462
chr4_-_22443110 1.44 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr6_+_121437378 1.43 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr5_+_36606355 1.43 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr5_-_135578983 1.42 ENST00000512158.6
C-X-C motif chemokine ligand 14
chr3_+_35643621 1.40 ENST00000419330.5
cAMP regulated phosphoprotein 21
chr1_-_159862648 1.37 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr11_+_45896541 1.35 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr7_-_13988863 1.29 ENST00000405358.8
ETS variant transcription factor 1
chr5_-_97142753 1.28 ENST00000512378.1
limb and CNS expressed 1
chrX_-_23907887 1.28 ENST00000379226.9
apolipoprotein O
chr12_-_16608183 1.25 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr1_+_177170916 1.24 ENST00000361539.5
BMP/retinoic acid inducible neural specific 2
chr8_-_42501224 1.21 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr8_+_42541128 1.19 ENST00000438528.7
small integral membrane protein 19
chrX_-_32412220 1.18 ENST00000619831.5
dystrophin
chrX_+_11822423 1.17 ENST00000656302.1
ENST00000640291.2
FERM and PDZ domain containing 4
chr12_-_16608073 1.16 ENST00000441439.6
LIM domain only 3
chr15_+_67098582 1.16 ENST00000559092.1
ENST00000560175.5
SMAD family member 3
chr9_-_76906090 1.14 ENST00000376718.8
prune homolog 2 with BCH domain
chr6_-_87095059 1.11 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr12_-_99984227 1.11 ENST00000547776.6
ENST00000547010.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_26572102 1.09 ENST00000455601.6
mucin 15, cell surface associated
chr8_+_76681208 1.09 ENST00000651372.2
zinc finger homeobox 4
chr15_+_58410543 1.06 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr11_-_26572130 1.05 ENST00000527569.1
mucin 15, cell surface associated
chr7_+_129375643 1.05 ENST00000490911.5
adenosylhomocysteinase like 2
chr11_-_70826887 1.05 ENST00000656230.1
SH3 and multiple ankyrin repeat domains 2
chr4_-_86360010 1.05 ENST00000641911.1
ENST00000641072.1
ENST00000359221.8
ENST00000640490.1
mitogen-activated protein kinase 10
chr5_+_90640718 1.05 ENST00000640403.1
adhesion G protein-coupled receptor V1
chr7_+_129368123 1.04 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr14_-_36519679 1.04 ENST00000498187.6
NK2 homeobox 1
chr18_+_63702958 1.04 ENST00000544088.6
serpin family B member 11
chr3_+_189789643 1.04 ENST00000354600.10
tumor protein p63
chr2_-_2324323 1.04 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr12_-_70637405 1.03 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr5_-_140346596 1.01 ENST00000230990.7
heparin binding EGF like growth factor
chr3_+_111999326 1.01 ENST00000494932.1
transgelin 3
chr13_+_77741331 0.99 ENST00000462234.5
SLAIN motif family member 1
chrX_-_21658324 0.97 ENST00000379499.3
kelch like family member 34
chr13_+_77741393 0.95 ENST00000496045.5
SLAIN motif family member 1
chr17_+_50165990 0.95 ENST00000262018.8
ENST00000344627.10
ENST00000682109.1
ENST00000504073.2
sarcoglycan alpha
chr5_-_157059109 0.95 ENST00000523175.6
ENST00000522693.5
hepatitis A virus cellular receptor 1
chr12_-_16610037 0.94 ENST00000540590.1
LIM domain only 3
chr14_-_26598025 0.92 ENST00000539517.7
NOVA alternative splicing regulator 1
chr22_+_20550981 0.92 ENST00000457322.5
mediator complex subunit 15
chr6_+_151325665 0.92 ENST00000354675.10
A-kinase anchoring protein 12
chr4_-_99144238 0.88 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
alcohol dehydrogenase 4 (class II), pi polypeptide
chr20_+_43559060 0.86 ENST00000485914.2
serum/glucocorticoid regulated kinase 2
chr1_+_99646025 0.85 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr13_-_44161257 0.83 ENST00000400419.2
small integral membrane protein 2
chr12_+_15546344 0.82 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr12_-_130633825 0.82 ENST00000541840.2
RIMS binding protein 2
chr17_+_7407838 0.81 ENST00000302926.7
neuroligin 2
chrX_-_18672101 0.79 ENST00000379984.4
retinoschisin 1
chr1_-_47190013 0.78 ENST00000294338.7
PDZK1 interacting protein 1
chr2_+_6978624 0.78 ENST00000433456.1
ring finger protein 144A
chr1_-_193059489 0.77 ENST00000367455.8
ENST00000421683.1
ubiquitin C-terminal hydrolase L5
chr21_-_34526850 0.77 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chr1_-_193059296 0.76 ENST00000367450.7
ENST00000367451.8
ENST00000367454.6
ENST00000367448.5
ENST00000367449.5
ubiquitin C-terminal hydrolase L5
chr7_+_117020191 0.72 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr6_+_50818857 0.72 ENST00000393655.4
transcription factor AP-2 beta
chr1_+_50108856 0.71 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr22_+_20551135 0.69 ENST00000424287.5
ENST00000423862.5
mediator complex subunit 15
chr11_+_65787056 0.69 ENST00000335987.8
ovo like transcriptional repressor 1
chr7_+_129375830 0.69 ENST00000466993.5
adenosylhomocysteinase like 2
chr17_+_75543258 0.69 ENST00000581713.5
LLGL scribble cell polarity complex component 2
chr6_-_142946312 0.66 ENST00000367604.6
HIVEP zinc finger 2
chr4_+_112860912 0.66 ENST00000671951.1
ankyrin 2
chr6_-_155314444 0.65 ENST00000367166.5
transcription factor B1, mitochondrial
chr6_-_138545685 0.64 ENST00000342260.9
NHS like 1
chr21_-_30492008 0.64 ENST00000334063.6
keratin associated protein 19-3
chr17_+_12955763 0.63 ENST00000583608.1
Rho GTPase activating protein 44
chr1_+_50105666 0.61 ENST00000651347.1
ELAV like RNA binding protein 4
chr22_+_20551000 0.60 ENST00000428629.5
mediator complex subunit 15
chr4_-_73620391 0.60 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr4_+_87650277 0.59 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr11_-_93850559 0.58 ENST00000409977.2
V-set and transmembrane domain containing 5
chr10_-_73655984 0.58 ENST00000394810.3
synaptopodin 2 like
chr4_+_112861053 0.58 ENST00000672221.1
ankyrin 2
chr4_-_65670478 0.57 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPH receptor A5
chr21_-_31038476 0.57 ENST00000382822.2
keratin associated protein 19-8
chr4_+_112860981 0.57 ENST00000671704.1
ankyrin 2
chr5_+_132873660 0.56 ENST00000296877.3
liver enriched antimicrobial peptide 2
chr4_+_109827963 0.54 ENST00000317735.7
retinal pigment epithelium-derived rhodopsin homolog
chr21_-_34526815 0.54 ENST00000492600.1
regulator of calcineurin 1
chr1_-_153150884 0.53 ENST00000368748.5
small proline rich protein 2G
chr5_-_124746630 0.53 ENST00000513986.2
zinc finger protein 608
chr5_+_127649018 0.52 ENST00000379445.7
cortexin 3
chr3_-_127822455 0.50 ENST00000265052.10
monoglyceride lipase
chr2_+_28778848 0.50 ENST00000418910.1
protein phosphatase 1 catalytic subunit beta
chr6_+_25754699 0.49 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chr1_-_10964201 0.49 ENST00000418570.6
chromosome 1 open reading frame 127
chr4_-_73620629 0.46 ENST00000342081.7
Ras association domain family member 6
chr22_-_50085414 0.46 ENST00000311597.10
modulator of VRAC current 1
chr3_+_189789672 0.45 ENST00000434928.5
tumor protein p63
chr17_-_41424583 0.44 ENST00000225550.4
keratin 37
chr7_+_1232865 0.42 ENST00000316333.9
UNC homeobox
chr13_-_44160855 0.41 ENST00000617002.1
small integral membrane protein 2
chrX_+_30235894 0.41 ENST00000620842.1
MAGE family member B3
chr6_+_75620639 0.40 ENST00000483859.6
SUMO specific peptidase 6
chr19_+_38374549 0.40 ENST00000620216.4
proteasome 26S subunit, non-ATPase 8
chr13_+_97960192 0.40 ENST00000496368.6
ENST00000421861.7
ENST00000357602.7
importin 5
chr12_-_85836372 0.37 ENST00000361228.5
Ras association domain family member 9
chr19_+_38374557 0.37 ENST00000215071.9
proteasome 26S subunit, non-ATPase 8
chr19_-_7632971 0.37 ENST00000598935.5
Purkinje cell protein 2
chr1_+_45913647 0.35 ENST00000674079.1
microtubule associated serine/threonine kinase 2
chr5_+_135579193 0.34 ENST00000646290.1
solute carrier family 25 member 48
chr15_-_37101205 0.34 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
Meis homeobox 2
chr11_-_72112068 0.34 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr1_-_208244375 0.34 ENST00000367033.4
plexin A2
chr2_-_80304700 0.33 ENST00000295057.4
leucine rich repeat transmembrane neuronal 1
chr22_-_50085331 0.33 ENST00000395876.6
modulator of VRAC current 1
chr10_+_18260715 0.32 ENST00000615785.4
ENST00000617363.4
ENST00000396576.6
calcium voltage-gated channel auxiliary subunit beta 2
chr22_-_50085378 0.31 ENST00000442311.1
modulator of VRAC current 1
chr8_+_26293112 0.30 ENST00000523925.5
ENST00000315985.7
protein phosphatase 2 regulatory subunit Balpha
chr6_+_50818701 0.30 ENST00000344788.7
transcription factor AP-2 beta
chr11_-_72112669 0.30 ENST00000545944.5
ENST00000502597.2
anaphase promoting complex subunit 15
chr7_-_143885356 0.30 ENST00000485416.1
TRPM8 channel associated factor 1
chr14_-_20641691 0.29 ENST00000320704.3
olfactory receptor family 6 subfamily S member 1
chr6_+_42155399 0.28 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr11_-_72112750 0.28 ENST00000545680.5
ENST00000543587.5
ENST00000538393.5
ENST00000535234.5
ENST00000227618.8
ENST00000535503.5
anaphase promoting complex subunit 15
chr3_+_2511597 0.28 ENST00000434053.5
contactin 4
chr6_+_158017048 0.26 ENST00000638626.1
synaptojanin 2
chr13_+_57631735 0.26 ENST00000377918.8
protocadherin 17
chr9_-_114806031 0.25 ENST00000374045.5
TNF superfamily member 15
chr3_-_51875597 0.24 ENST00000446461.2
IQ motif containing F5
chr10_+_47322450 0.24 ENST00000581492.3
growth differentiation factor 2
chr17_-_41397600 0.22 ENST00000251645.3
keratin 31
chr5_+_141412979 0.22 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr19_+_9093179 0.21 ENST00000429566.3
olfactory receptor family 1 subfamily M member 1
chrX_+_23908006 0.20 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr1_-_201171545 0.19 ENST00000367333.6
transmembrane protein 9
chr4_-_73620500 0.19 ENST00000335049.5
Ras association domain family member 6
chr1_+_45913583 0.19 ENST00000372008.6
microtubule associated serine/threonine kinase 2
chr1_+_193059448 0.18 ENST00000432079.5
Ro60, Y RNA binding protein
chr11_-_31509569 0.18 ENST00000526776.5
inner mitochondrial membrane peptidase subunit 1
chr11_-_120138104 0.18 ENST00000341846.10
tripartite motif containing 29
chr6_+_150721073 0.17 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr11_-_36598221 0.17 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr6_-_33192454 0.17 ENST00000395194.1
ENST00000341947.7
ENST00000374708.8
collagen type XI alpha 2 chain
chr5_-_141618914 0.16 ENST00000518047.5
diaphanous related formin 1
chr11_-_70826716 0.16 ENST00000468619.6
SH3 and multiple ankyrin repeat domains 2
chr17_+_18183052 0.15 ENST00000541285.1
alkB homolog 5, RNA demethylase
chr2_-_80304274 0.15 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr9_-_13165442 0.14 ENST00000542239.1
ENST00000538841.5
ENST00000433359.6
multiple PDZ domain crumbs cell polarity complex component
chr21_+_32298849 0.13 ENST00000303645.10
melanocortin 2 receptor accessory protein
chr1_+_207325629 0.13 ENST00000618707.2
CD55 molecule (Cromer blood group)
chr4_+_174283699 0.12 ENST00000505124.5
centrosomal protein 44
chr17_+_18183803 0.11 ENST00000399138.5
alkB homolog 5, RNA demethylase
chr3_+_77039836 0.11 ENST00000461745.5
roundabout guidance receptor 2
chr12_-_15662692 0.11 ENST00000540613.5
epidermal growth factor receptor pathway substrate 8
chr15_+_101812202 0.10 ENST00000332238.5
olfactory receptor family 4 subfamily F member 15
chr4_-_174283614 0.09 ENST00000513696.1
ENST00000393674.7
ENST00000503293.5
F-box protein 8

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 11.6 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.9 2.8 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.9 7.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 3.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.7 6.0 GO:0015811 L-cystine transport(GO:0015811)
0.6 2.8 GO:1900127 negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.5 2.7 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5 2.9 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.4 1.4 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3 2.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 1.0 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.3 4.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.3 5.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 2.0 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 1.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.8 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.8 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2 3.3 GO:0019532 oxalate transport(GO:0019532)
0.2 3.6 GO:0070166 enamel mineralization(GO:0070166)
0.2 1.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.5 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 1.0 GO:0051541 elastin metabolic process(GO:0051541)
0.1 1.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.4 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 1.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.0 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 2.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.9 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 3.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.3 GO:1990709 presynaptic active zone organization(GO:1990709)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.5 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 1.3 GO:0042407 cristae formation(GO:0042407)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 3.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.0 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.1 GO:0071397 regulation of response to osmotic stress(GO:0047484) cellular response to cholesterol(GO:0071397)
0.0 0.9 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.0 2.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.9 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 3.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 1.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 2.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 1.2 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0031167 rRNA methylation(GO:0031167)
0.0 2.7 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.3 GO:0061617 MICOS complex(GO:0061617)
0.2 2.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.3 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.4 GO:0032982 myosin filament(GO:0032982)
0.1 1.2 GO:0005883 neurofilament(GO:0005883)
0.1 1.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 6.0 GO:0031526 brush border membrane(GO:0031526)
0.1 0.2 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 1.4 GO:0005922 connexon complex(GO:0005922)
0.0 4.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 4.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.8 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.9 GO:0043209 myelin sheath(GO:0043209)
0.0 5.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.7 6.0 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 5.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 1.8 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.4 2.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 8.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.9 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.3 2.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 3.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 3.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 2.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.9 GO:0035276 ethanol binding(GO:0035276)
0.1 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 3.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.8 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 3.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 1.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 1.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 1.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.9 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 5.8 GO:0051015 actin filament binding(GO:0051015)
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 4.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 1.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.4 PID IGF1 PATHWAY IGF1 pathway
0.0 1.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 1.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 5.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 2.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.9 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 2.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 3.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 6.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 7.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 1.0 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 4.6 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6