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Illumina Body Map 2 (GSE30611)
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Results for PPARG
Z-value: 1.71
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Transcription factors associated with PPARG
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PPARG
|
ENSG00000132170.24 | peroxisome proliferator activated receptor gamma |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PPARG | hg38_v1_chr3_+_12287899_12287943 | 0.37 | 3.9e-02 | Click! |
Activity profile of PPARG motif
Sorted Z-values of PPARG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of PPARG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.9 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 2.2 | 11.0 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 1.7 | 5.2 | GO:0010933 | macrophage tolerance induction(GO:0010931) regulation of macrophage tolerance induction(GO:0010932) positive regulation of macrophage tolerance induction(GO:0010933) |
| 1.6 | 6.4 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 1.0 | 4.1 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.9 | 2.6 | GO:0002818 | intracellular defense response(GO:0002818) |
| 0.8 | 1.6 | GO:0071661 | granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) |
| 0.7 | 2.8 | GO:0070434 | positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434) |
| 0.7 | 2.0 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.6 | 3.8 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
| 0.6 | 1.9 | GO:1900154 | regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155) |
| 0.6 | 1.8 | GO:0002436 | immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439) |
| 0.6 | 4.6 | GO:0046642 | negative regulation of alpha-beta T cell proliferation(GO:0046642) |
| 0.6 | 1.1 | GO:0044691 | tooth eruption(GO:0044691) |
| 0.5 | 3.3 | GO:0038112 | interleukin-8-mediated signaling pathway(GO:0038112) |
| 0.5 | 2.5 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.5 | 6.3 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 0.5 | 0.9 | GO:0035419 | activation of MAPK activity involved in innate immune response(GO:0035419) |
| 0.5 | 4.2 | GO:0002353 | kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
| 0.4 | 74.2 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.4 | 3.4 | GO:0050689 | negative regulation of defense response to virus by host(GO:0050689) |
| 0.4 | 3.0 | GO:1903923 | protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923) |
| 0.4 | 9.0 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.4 | 2.1 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
| 0.3 | 3.7 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.3 | 1.3 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.3 | 9.4 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.3 | 9.7 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.3 | 2.1 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.3 | 1.7 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.3 | 1.4 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.3 | 0.8 | GO:0045554 | TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556) |
| 0.3 | 0.5 | GO:0001300 | chronological cell aging(GO:0001300) |
| 0.3 | 1.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
| 0.3 | 1.5 | GO:1903238 | positive regulation of leukocyte tethering or rolling(GO:1903238) |
| 0.2 | 2.7 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.2 | 3.2 | GO:0070543 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.2 | 1.0 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
| 0.2 | 1.4 | GO:0070221 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 0.2 | 0.6 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.2 | 1.2 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 0.2 | 2.3 | GO:0033629 | negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.2 | 1.3 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.2 | 1.1 | GO:0036079 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.2 | 1.6 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.2 | 2.3 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.2 | 2.2 | GO:1903944 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.2 | 2.0 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.2 | 0.8 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.2 | 0.5 | GO:0036510 | trimming of terminal mannose on C branch(GO:0036510) |
| 0.2 | 3.5 | GO:0015816 | glycine transport(GO:0015816) |
| 0.2 | 0.6 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 0.2 | 2.6 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.1 | 0.4 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
| 0.1 | 0.7 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.1 | 1.1 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
| 0.1 | 0.7 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.1 | 0.7 | GO:0018057 | peptidyl-lysine oxidation(GO:0018057) |
| 0.1 | 2.3 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 1.1 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
| 0.1 | 0.7 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.1 | 1.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 2.0 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 2.0 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.1 | 1.4 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.1 | 0.6 | GO:0030581 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.1 | 5.3 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 0.6 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.1 | 3.4 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.1 | 4.4 | GO:0034755 | iron ion transmembrane transport(GO:0034755) |
| 0.1 | 1.0 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.1 | 0.8 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.1 | 3.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.1 | 1.0 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.1 | 0.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.1 | 2.2 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) |
| 0.1 | 0.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 0.4 | GO:1902463 | protein localization to cell leading edge(GO:1902463) |
| 0.1 | 2.1 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
| 0.1 | 11.2 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 0.1 | 1.3 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
| 0.1 | 1.0 | GO:1900084 | regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086) |
| 0.1 | 1.0 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 0.9 | GO:0048007 | antigen processing and presentation via MHC class Ib(GO:0002475) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.1 | 2.3 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.1 | 16.2 | GO:0002377 | immunoglobulin production(GO:0002377) |
| 0.1 | 0.5 | GO:0019557 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.1 | 1.2 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.1 | 3.8 | GO:2001044 | regulation of integrin-mediated signaling pathway(GO:2001044) |
| 0.1 | 2.7 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.1 | 1.2 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 1.4 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 2.9 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 2.0 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.1 | 0.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.1 | 0.5 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 0.5 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.1 | 1.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 0.8 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 0.9 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.1 | 1.3 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.1 | 0.8 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 1.6 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.1 | 2.7 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.1 | 0.6 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 0.2 | GO:0072287 | metanephric distal tubule morphogenesis(GO:0072287) |
| 0.0 | 2.6 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.0 | 0.9 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 0.5 | GO:1902019 | regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019) |
| 0.0 | 1.2 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.0 | 5.5 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.0 | 2.1 | GO:0001893 | maternal placenta development(GO:0001893) |
| 0.0 | 0.2 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.0 | 0.3 | GO:1902045 | negative regulation of Fas signaling pathway(GO:1902045) |
| 0.0 | 0.5 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
| 0.0 | 0.2 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.0 | 0.0 | GO:0002458 | peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) tolerance induction to self antigen(GO:0002513) regulation of thymocyte migration(GO:2000410) |
| 0.0 | 0.6 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
| 0.0 | 0.5 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 0.3 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.0 | 0.4 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 1.3 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.0 | 7.9 | GO:0045995 | regulation of embryonic development(GO:0045995) |
| 0.0 | 0.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
| 0.0 | 1.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 2.4 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 2.0 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.0 | 0.2 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.0 | 1.0 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.0 | 0.5 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 1.0 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.0 | 0.2 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.0 | 1.3 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.0 | 0.1 | GO:0046292 | formaldehyde metabolic process(GO:0046292) |
| 0.0 | 0.3 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.0 | 0.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 3.4 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 1.4 | GO:0097503 | sialylation(GO:0097503) |
| 0.0 | 1.6 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.2 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.4 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 0.4 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.2 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.0 | 1.6 | GO:1902475 | L-alpha-amino acid transmembrane transport(GO:1902475) |
| 0.0 | 0.7 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.0 | 2.3 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.8 | GO:0006298 | mismatch repair(GO:0006298) |
| 0.0 | 0.1 | GO:0033504 | floor plate development(GO:0033504) |
| 0.0 | 2.9 | GO:0007498 | mesoderm development(GO:0007498) |
| 0.0 | 0.8 | GO:0042531 | positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531) |
| 0.0 | 2.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.2 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.0 | 0.8 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 0.0 | 0.1 | GO:0071486 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.0 | 0.7 | GO:0031663 | lipopolysaccharide-mediated signaling pathway(GO:0031663) |
| 0.0 | 2.0 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
| 0.0 | 0.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.4 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.3 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.2 | GO:0060992 | response to fungicide(GO:0060992) |
| 0.0 | 0.6 | GO:0010043 | response to zinc ion(GO:0010043) |
| 0.0 | 0.2 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 0.1 | GO:0050916 | sensory perception of sweet taste(GO:0050916) |
| 0.0 | 0.3 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.0 | 0.5 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.6 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 8.2 | GO:0002283 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.0 | 0.6 | GO:0006270 | DNA replication initiation(GO:0006270) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 9.0 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 1.4 | 13.6 | GO:0044194 | cytolytic granule(GO:0044194) |
| 1.1 | 5.6 | GO:0071754 | IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756) |
| 0.4 | 21.9 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.4 | 3.6 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.4 | 1.1 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
| 0.3 | 2.1 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.3 | 1.7 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.3 | 2.7 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.3 | 8.6 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.3 | 0.8 | GO:0005600 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
| 0.2 | 1.3 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 0.2 | 1.2 | GO:0032449 | CBM complex(GO:0032449) |
| 0.2 | 0.5 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 0.2 | 1.9 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.2 | 1.1 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.1 | 7.0 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 1.8 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 18.5 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 2.2 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 1.6 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.1 | 10.9 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 0.4 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 3.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.8 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.1 | 0.7 | GO:0097487 | multivesicular body, internal vesicle(GO:0097487) |
| 0.1 | 0.8 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 6.0 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 1.8 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 8.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.5 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 1.9 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.2 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.0 | 0.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 0.2 | GO:0002133 | polycystin complex(GO:0002133) |
| 0.0 | 1.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.0 | 0.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 4.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.6 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
| 0.0 | 2.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 7.0 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 8.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.0 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 2.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 1.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.9 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 2.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.4 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.6 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 2.0 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 0.9 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 1.6 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 6.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.1 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 4.4 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 1.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 25.9 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 1.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.2 | GO:0005845 | mRNA cap binding complex(GO:0005845) |
| 0.0 | 0.8 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 1.8 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 6.7 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.5 | GO:0005604 | basement membrane(GO:0005604) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 7.9 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.8 | 4.1 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.8 | 3.1 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.8 | 2.3 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 0.6 | 3.8 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.5 | 3.3 | GO:0004918 | interleukin-8 receptor activity(GO:0004918) |
| 0.5 | 2.8 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.5 | 1.9 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.5 | 1.8 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.4 | 2.1 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.4 | 2.7 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.4 | 1.1 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.3 | 9.0 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.3 | 9.4 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.3 | 91.6 | GO:0003823 | antigen binding(GO:0003823) |
| 0.3 | 3.1 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.3 | 6.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.3 | 9.7 | GO:0022829 | wide pore channel activity(GO:0022829) |
| 0.3 | 1.4 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.3 | 1.9 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 0.3 | 3.2 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.3 | 3.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.3 | 3.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 1.1 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) |
| 0.2 | 0.9 | GO:0050253 | retinyl-palmitate esterase activity(GO:0050253) |
| 0.2 | 3.0 | GO:0036122 | BMP binding(GO:0036122) |
| 0.2 | 0.6 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.2 | 0.6 | GO:0005046 | KDEL sequence binding(GO:0005046) |
| 0.2 | 7.0 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 2.0 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 2.4 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.2 | 3.5 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.2 | 1.1 | GO:0036080 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.2 | 1.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.2 | 0.8 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.2 | 0.6 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 0.1 | 4.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 1.2 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.1 | 1.0 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.8 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.1 | 1.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 1.6 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.1 | 1.1 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.1 | 0.8 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 1.1 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 1.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.1 | 6.4 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 1.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 0.9 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 7.6 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.1 | 0.5 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.1 | 0.5 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 1.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 2.6 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 0.7 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.1 | 9.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 2.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 7.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.7 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 2.2 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 1.9 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 0.5 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.1 | 1.3 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 2.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 1.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 2.0 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.5 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 1.6 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 0.9 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.1 | 4.1 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 2.1 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.0 | 0.6 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
| 0.0 | 1.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 1.1 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 2.2 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.2 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 0.2 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.0 | 7.9 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 1.3 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.6 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.0 | 0.4 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.6 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 0.0 | 8.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.6 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.0 | 0.3 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.2 | GO:0016803 | ether hydrolase activity(GO:0016803) |
| 0.0 | 1.2 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.7 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.6 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.5 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.4 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 2.6 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.2 | GO:1901567 | icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567) |
| 0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.0 | 2.8 | GO:0019209 | kinase activator activity(GO:0019209) |
| 0.0 | 4.6 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.7 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.6 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 5.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 5.4 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 1.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.0 | 0.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.4 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 0.7 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 1.6 | GO:0015179 | L-amino acid transmembrane transporter activity(GO:0015179) |
| 0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 1.4 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.7 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.0 | 0.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 7.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 3.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.7 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 3.1 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.3 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.3 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.2 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 11.0 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.2 | 9.8 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.2 | 11.1 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.1 | 9.4 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 7.7 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 3.3 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 2.2 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.1 | 4.6 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 3.5 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 2.1 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 1.5 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 1.5 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 4.3 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 3.3 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.9 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.3 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 2.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.1 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 1.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.8 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 4.2 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 1.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 3.7 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 5.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 1.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.5 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.8 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.6 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.6 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.5 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.6 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 3.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.2 | 2.7 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 9.1 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 9.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 5.2 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 3.2 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.1 | 3.0 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.1 | 12.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.3 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 2.0 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 2.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.1 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.1 | 0.8 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.1 | 7.4 | REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | Genes involved in Antigen processing-Cross presentation |
| 0.1 | 1.1 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 5.1 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.2 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 4.3 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 1.2 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.1 | 2.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.1 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 1.0 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 4.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 2.6 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 5.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 4.6 | REACTOME COSTIMULATION BY THE CD28 FAMILY | Genes involved in Costimulation by the CD28 family |
| 0.0 | 2.3 | REACTOME PKB MEDIATED EVENTS | Genes involved in PKB-mediated events |
| 0.0 | 1.6 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.0 | 1.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 3.6 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 2.8 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.0 | 1.0 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.0 | 0.5 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 1.0 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.4 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 1.1 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.4 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 2.6 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 2.5 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.0 | 0.2 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 0.2 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.7 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.8 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 0.7 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.1 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |