ISMARA results: PRDM1

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Illumina Body Map 2 (GSE30611)

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Results for PRDM1

Z-value: 1.93

Motif logo

Transcription factors associated with PRDM1

Gene Symbol	Gene ID	Gene Info
PRDM1 Ensembl NCBI GeneCards UniProt	ENSG00000057657.17	PR/SET domain 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
PRDM1	hg38_v1_chr6_+_106086316_106086349	0.35	5.0e-02	Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr9_-_34710069 Show fit	11.85	ENST00000378792.1 ENST00000259607.7	CCL21 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 21
chr10_-_44385043 Show fit	8.90	ENST00000374426.6 ENST00000395794.2 ENST00000374429.6 ENST00000395793.7 ENST00000343575.10 ENST00000395795.5	CXCL12 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 12
chr4_-_99321362 Show fit	8.25	ENST00000625860.2 ENST00000305046.13 ENST00000506651.5	ADH1B Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_+_46380746 Show fit	5.44	ENST00000405308.6	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr9_+_134641768 Show fit	5.30	ENST00000371817.8 ENST00000618395.4	COL5A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type V alpha 1 chain
chr22_-_30246739 Show fit	5.30	ENST00000403987.3 ENST00000249075.4	LIF Ensembl NCBI GeneCards UniProt Show fit	LIF interleukin 6 family cytokine
chr11_+_46381033 Show fit	5.05	ENST00000359803.7	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr15_-_37101205 Show fit	4.92	ENST00000338564.9 ENST00000558313.5 ENST00000340545.9	MEIS2 Ensembl NCBI GeneCards UniProt Show fit	Meis homeobox 2
chr3_+_8501846 Show fit	4.90	ENST00000454244.4	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine rich domains 1
chr3_+_8501807 Show fit	4.83	ENST00000426878.2 ENST00000397386.7 ENST00000415597.5 ENST00000157600.8	LMCD1 Ensembl NCBI GeneCards UniProt Show fit	LIM and cysteine rich domains 1
chr7_+_134779663 Show fit	4.35	ENST00000361901.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr7_+_134779625 Show fit	4.25	ENST00000454108.5 ENST00000361675.7	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr8_+_133191029 Show fit	4.08	ENST00000250160.11	CCN4 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 4
chr6_-_29559724 Show fit	4.08	ENST00000377050.5	UBD Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr11_+_46381194 Show fit	4.05	ENST00000533952.5	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr17_-_43018045 Show fit	3.99	ENST00000587147.1	VAT1 Ensembl NCBI GeneCards UniProt Show fit	vesicle amine transport 1
chr2_+_238848029 Show fit	3.91	ENST00000448943.2 ENST00000612363.2	TWIST2 Ensembl NCBI GeneCards UniProt Show fit	twist family bHLH transcription factor 2
chr12_-_57111338 Show fit	3.82	ENST00000538913.6 ENST00000537215.6 ENST00000300134.8 ENST00000454075.7 ENST00000640254.2 ENST00000553275.1 ENST00000553533.2	STAT6 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr5_+_93583212 Show fit	3.79	ENST00000327111.8	NR2F1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 1
chr19_-_42528380 Show fit	3.76	ENST00000403461.5 ENST00000352591.9 ENST00000358394.7 ENST00000403444.7 ENST00000161559.11 ENST00000599389.1	CEACAM1 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 1
chr14_-_68793055 Show fit	3.60	ENST00000439696.3	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr10_-_5977589 Show fit	3.43	ENST00000620345.4 ENST00000397251.7 ENST00000397248.6 ENST00000622442.4 ENST00000620865.4	IL15RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor subunit alpha
chr8_+_96493803 Show fit	3.43	ENST00000518385.5 ENST00000302190.9	SDC2 Ensembl NCBI GeneCards UniProt Show fit	syndecan 2
chrX_-_155334580 Show fit	3.42	ENST00000369449.7 ENST00000321926.4	CLIC2 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 2
chr3_-_86991135 Show fit	3.37	ENST00000398399.7	VGLL3 Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 3
chr1_-_44031446 Show fit	3.36	ENST00000372310.8 ENST00000466926.1	SLC6A9 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 9
chr10_-_5978022 Show fit	3.36	ENST00000525219.6	IL15RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor subunit alpha
chr1_+_109910840 Show fit	3.36	ENST00000329608.11 ENST00000488198.5	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr21_-_38661694 Show fit	3.31	ENST00000417133.6 ENST00000398910.5 ENST00000442448.5 ENST00000429727.6	ERG Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ERG
chr4_-_137532452 Show fit	3.06	ENST00000412923.6 ENST00000511115.5 ENST00000344876.9 ENST00000507846.5 ENST00000510305.5 ENST00000611581.1	PCDH18 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 18
chr10_-_5977535 Show fit	3.02	ENST00000379977.8	IL15RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor subunit alpha
chr1_-_111204343 Show fit	2.95	ENST00000369752.5	DENND2D Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 2D
chr1_+_212608628 Show fit	2.93	ENST00000613954.4 ENST00000341491.9 ENST00000366985.5	ATF3 Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr3_-_49813880 Show fit	2.92	ENST00000333486.4	UBA7 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 7
chr16_-_88785210 Show fit	2.90	ENST00000301015.14	PIEZO1 Ensembl NCBI GeneCards UniProt Show fit	piezo type mechanosensitive ion channel component 1
chr3_-_169146595 Show fit	2.89	ENST00000468789.5	MECOM Ensembl NCBI GeneCards UniProt Show fit	MDS1 and EVI1 complex locus
chr6_+_127118657 Show fit	2.88	ENST00000356698.9	RSPO3 Ensembl NCBI GeneCards UniProt Show fit	R-spondin 3
chr4_+_186069144 Show fit	2.79	ENST00000513189.1 ENST00000296795.8	TLR3 Ensembl NCBI GeneCards UniProt Show fit	toll like receptor 3
chr22_-_36160773 Show fit	2.77	ENST00000531095.1 ENST00000349314.6 ENST00000397293.6	APOL3 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L3
chr9_+_18474100 Show fit	2.76	ENST00000327883.11 ENST00000431052.6 ENST00000380570.8 ENST00000380548.9	ADAMTSL1 Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 1
chr14_-_68796230 Show fit	2.73	ENST00000557086.1	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr1_+_109910986 Show fit	2.64	ENST00000369801.1	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr19_-_48752628 Show fit	2.62	ENST00000645652.2	FUT1 Ensembl NCBI GeneCards UniProt Show fit	fucosyltransferase 1 (H blood group)
chr6_+_151690492 Show fit	2.62	ENST00000404742.5 ENST00000440973.5	ESR1 Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor 1
chr11_+_71998892 Show fit	2.61	ENST00000393705.8 ENST00000393703.9 ENST00000337131.9 ENST00000620017.4 ENST00000531053.5 ENST00000404792.5	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr14_-_68796199 Show fit	2.57	ENST00000553375.1	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr2_+_69013170 Show fit	2.56	ENST00000303714.9	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr14_-_68796054 Show fit	2.56	ENST00000557022.1	ZFP36L1 Ensembl NCBI GeneCards UniProt Show fit	ZFP36 ring finger protein like 1
chr1_+_200027702 Show fit	2.42	ENST00000367362.8	NR5A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 5 group A member 2
chr17_-_40364722 Show fit	2.40	ENST00000578689.2	GJD3 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein delta 3
chr17_+_43006740 Show fit	2.38	ENST00000438323.2 ENST00000415816.7	IFI35 Ensembl NCBI GeneCards UniProt Show fit	interferon induced protein 35
chr7_-_41703062 Show fit	2.37	ENST00000242208.5	INHBA Ensembl NCBI GeneCards UniProt Show fit	inhibin subunit beta A
chr10_-_5977492 Show fit	2.37	ENST00000530685.5 ENST00000397255.7 ENST00000379971.5 ENST00000528354.5 ENST00000397250.6 ENST00000429135.2	IL15RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 15 receptor subunit alpha
chr7_+_114416286 Show fit	2.36	ENST00000635534.1	FOXP2 Ensembl NCBI GeneCards UniProt Show fit	forkhead box P2
chr12_-_57111192 Show fit	2.35	ENST00000553397.5 ENST00000556259.5	STAT6 Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr12_-_70609788 Show fit	2.31	ENST00000547715.1 ENST00000538708.5 ENST00000550857.5 ENST00000261266.9	PTPRB Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type B
chr1_+_109910892 Show fit	2.30	ENST00000369802.7 ENST00000420111.6	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr13_+_101452629 Show fit	2.26	ENST00000622834.4 ENST00000545560.6 ENST00000376180.8	ITGBL1 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta like 1
chr1_+_200027605 Show fit	2.23	ENST00000236914.7	NR5A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 5 group A member 2
chr22_+_39077264 Show fit	2.21	ENST00000407997.4	APOBEC3G Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr11_+_32091065 Show fit	2.16	ENST00000054950.4	RCN1 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 1
chr8_+_133191060 Show fit	2.10	ENST00000519433.1 ENST00000517423.5 ENST00000220856.6	CCN4 Ensembl NCBI GeneCards UniProt Show fit	cellular communication network factor 4
chr11_+_46380932 Show fit	2.10	ENST00000441869.5	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr4_+_125314918 Show fit	2.09	ENST00000674496.2 ENST00000394329.9	FAT4 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 4
chr22_+_39040857 Show fit	2.04	ENST00000381565.2 ENST00000308521.10	APOBEC3F Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3F
chr4_+_151099637 Show fit	2.02	ENST00000512690.5 ENST00000508783.5 ENST00000512797.5 ENST00000507327.5 ENST00000515792.5 ENST00000506126.5	RPS3A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S3A
chr2_+_230327218 Show fit	2.02	ENST00000243810.10 ENST00000396563.8	SP140L Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein like
chr19_+_33796846 Show fit	2.01	ENST00000590771.5 ENST00000589786.5 ENST00000284006.10 ENST00000683859.1 ENST00000588881.5	KCTD15 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 15
chr2_+_230327160 Show fit	2.00	ENST00000444636.5 ENST00000415673.7	SP140L Ensembl NCBI GeneCards UniProt Show fit	SP140 nuclear body protein like
chr11_+_63536801 Show fit	1.99	ENST00000255688.8 ENST00000439013.6	PLAAT4 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A and acyltransferase 4
chr11_+_71999603 Show fit	1.99	ENST00000260049.9	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr12_-_50167292 Show fit	1.97	ENST00000547800.2 ENST00000317551.12 ENST00000422340.6	CERS5 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 5
chr12_+_93572664 Show fit	1.96	ENST00000551556.2	SOCS2 Ensembl NCBI GeneCards UniProt Show fit	suppressor of cytokine signaling 2
chr6_+_130018565 Show fit	1.91	ENST00000361794.7 ENST00000526087.5 ENST00000533560.5	L3MBTL3 Ensembl NCBI GeneCards UniProt Show fit	L3MBTL histone methyl-lysine binding protein 3
chr4_+_151099584 Show fit	1.87	ENST00000509736.5 ENST00000505243.5 ENST00000274065.9 ENST00000514682.5 ENST00000503002.5	RPS3A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S3A
chr2_+_230416239 Show fit	1.87	ENST00000409824.5 ENST00000409341.5 ENST00000409112.5	SP100 Ensembl NCBI GeneCards UniProt Show fit	SP100 nuclear antigen
chr11_+_71999927 Show fit	1.82	ENST00000393707.4	IL18BP Ensembl NCBI GeneCards UniProt Show fit	interleukin 18 binding protein
chr2_+_230416156 Show fit	1.81	ENST00000427101.6	SP100 Ensembl NCBI GeneCards UniProt Show fit	SP100 nuclear antigen
chr22_+_39021113 Show fit	1.79	ENST00000427494.6 ENST00000216099.13	APOBEC3D Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 3D
chr4_+_145482761 Show fit	1.77	ENST00000507367.1 ENST00000394092.6 ENST00000515385.1	SMAD1 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 1
chr17_-_81860478 Show fit	1.70	ENST00000681693.1 ENST00000680226.1 ENST00000679439.1 ENST00000576390.6 ENST00000570907.6 ENST00000680191.1 ENST00000681020.1 ENST00000571617.2 ENST00000415593.6 ENST00000331483.9 ENST00000680914.1 ENST00000680593.1 ENST00000439918.7 ENST00000574914.2 ENST00000681161.1 ENST00000680884.1	P4HB Ensembl NCBI GeneCards UniProt Show fit	prolyl 4-hydroxylase subunit beta
chr1_-_44031352 Show fit	1.68	ENST00000372306.7 ENST00000475075.6	SLC6A9 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 9
chr2_-_223837553 Show fit	1.64	ENST00000396654.7 ENST00000396653.2 ENST00000443700.5	AP1S3 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 3
chr1_+_2556222 Show fit	1.64	ENST00000409119.5	TNFRSF14 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 14
chr4_-_99219230 Show fit	1.63	ENST00000394897.5 ENST00000508558.1 ENST00000394899.6	ADH6 Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase 6 (class V)
chr2_-_64019072 Show fit	1.60	ENST00000409558.8	VPS54 Ensembl NCBI GeneCards UniProt Show fit	VPS54 subunit of GARP complex
chr13_+_23570370 Show fit	1.59	ENST00000403372.6 ENST00000248484.9	TNFRSF19 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 19
chr5_+_134525649 Show fit	1.57	ENST00000282605.8 ENST00000681547.2 ENST00000361895.6 ENST00000402835.5	JADE2 Ensembl NCBI GeneCards UniProt Show fit	jade family PHD finger 2
chr4_+_15374541 Show fit	1.56	ENST00000382383.7 ENST00000429690.5	C1QTNF7 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 7
chr7_-_3043838 Show fit	1.56	ENST00000356408.3 ENST00000396946.9	CARD11 Ensembl NCBI GeneCards UniProt Show fit	caspase recruitment domain family member 11
chr9_+_132582581 Show fit	1.54	ENST00000263610.7	BARHL1 Ensembl NCBI GeneCards UniProt Show fit	BarH like homeobox 1
chr2_+_69013282 Show fit	1.53	ENST00000409829.7	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr10_+_113125536 Show fit	1.52	ENST00000349937.7	TCF7L2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr2_+_69013337 Show fit	1.51	ENST00000463335.2	ANTXR1 Ensembl NCBI GeneCards UniProt Show fit	ANTXR cell adhesion molecule 1
chr12_+_6452024 Show fit	1.50	ENST00000266556.8 ENST00000544021.5	TAPBPL Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein like
chr1_+_109910485 Show fit	1.49	ENST00000525659.5	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr6_-_166862502 Show fit	1.49	ENST00000510118.5 ENST00000503859.5 ENST00000506565.1	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr12_+_57522801 Show fit	1.48	ENST00000355673.8 ENST00000546632.1 ENST00000549623.1	MBD6 Ensembl NCBI GeneCards UniProt Show fit	methyl-CpG binding domain protein 6
chr3_-_45958572 Show fit	1.47	ENST00000433878.5	FYCO1 Ensembl NCBI GeneCards UniProt Show fit	FYVE and coiled-coil domain autophagy adaptor 1
chr12_-_106247950 Show fit	1.44	ENST00000378026.5	CKAP4 Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton associated protein 4
chr2_-_70248454 Show fit	1.36	ENST00000416149.6 ENST00000282574.8	TIA1 Ensembl NCBI GeneCards UniProt Show fit	TIA1 cytotoxic granule associated RNA binding protein
chr16_+_20674493 Show fit	1.31	ENST00000561584.5	ACSM3 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 3
chr2_+_230416190 Show fit	1.27	ENST00000340126.9 ENST00000432979.5	SP100 Ensembl NCBI GeneCards UniProt Show fit	SP100 nuclear antigen
chr6_+_118548289 Show fit	1.26	ENST00000357525.6	PLN Ensembl NCBI GeneCards UniProt Show fit	phospholamban
chr6_+_26383090 Show fit	1.21	ENST00000469230.5 ENST00000490025.5 ENST00000352867.6 ENST00000356709.9 ENST00000493275.5 ENST00000472507.5 ENST00000482536.5 ENST00000432533.6 ENST00000482842.1	BTN2A2 Ensembl NCBI GeneCards UniProt Show fit	butyrophilin subfamily 2 member A2
chr10_-_13707536 Show fit	1.20	ENST00000632570.1 ENST00000477221.2	FRMD4A Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 4A
chr6_+_106087580 Show fit	1.19	ENST00000424894.1 ENST00000648754.1	PRDM1 Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr18_-_49491586 Show fit	1.18	ENST00000584895.5 ENST00000580210.5 ENST00000579408.5	RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit RPL17 Ensembl NCBI GeneCards UniProt Show fit	RPL17-C18orf32 readthrough ribosomal protein L17
chr6_-_32843994 Show fit	1.17	ENST00000395339.7 ENST00000374882.8	PSMB8 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 8
chrX_-_139932994 Show fit	1.16	ENST00000682941.1 ENST00000370557.5	ATP11C Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 11C
chr14_-_24146596 Show fit	1.16	ENST00000560410.5 ENST00000216802.10 ENST00000615264.4 ENST00000630027.1	PSME2 Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chr1_+_109910581 Show fit	1.16	ENST00000357302.8	CSF1 Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr6_+_26156323 Show fit	1.13	ENST00000304218.6	H1-4 Ensembl NCBI GeneCards UniProt Show fit	H1.4 linker histone, cluster member
chrX_+_630789 Show fit	1.13	ENST00000381575.6	SHOX Ensembl NCBI GeneCards UniProt Show fit	short stature homeobox
chr5_+_96876480 Show fit	1.10	ENST00000437043.8 ENST00000379904.8	ERAP2 Ensembl NCBI GeneCards UniProt Show fit	endoplasmic reticulum aminopeptidase 2
chr11_+_64241053 Show fit	1.07	ENST00000309366.9 ENST00000449942.6 ENST00000652762.2	FKBP2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000286264.2 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 2 novel protein
chr14_-_24146314 Show fit	1.05	ENST00000559056.5	PSME2 Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 2
chr1_-_205356894 Show fit	1.03	ENST00000367155.8	KLHDC8A Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 8A
chr6_-_154510675 Show fit	1.01	ENST00000607772.6	CNKSR3 Ensembl NCBI GeneCards UniProt Show fit	CNKSR family member 3
chr1_+_215573775 Show fit	1.00	ENST00000448333.1	KCTD3 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 3
chrX_-_119693150 Show fit	0.95	ENST00000394610.7	SEPTIN6 Ensembl NCBI GeneCards UniProt Show fit	septin 6
chr12_-_120325936 Show fit	0.94	ENST00000549767.1	PLA2G1B Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IB
chr2_+_233681877 Show fit	0.94	ENST00000373426.4	UGT1A7 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A7
chr4_+_141636923 Show fit	0.91	ENST00000529613.5	IL15 Ensembl NCBI GeneCards UniProt Show fit	interleukin 15
chr14_-_24442662 Show fit	0.90	ENST00000554698.5	SDR39U1 Ensembl NCBI GeneCards UniProt Show fit	short chain dehydrogenase/reductase family 39U member 1
chr3_-_64445396 Show fit	0.90	ENST00000295902.11	PRICKLE2 Ensembl NCBI GeneCards UniProt Show fit	prickle planar cell polarity protein 2
chr20_+_32358303 Show fit	0.89	ENST00000651418.1 ENST00000375687.10 ENST00000542461.5 ENST00000613218.4 ENST00000646367.1 ENST00000620121.4	ASXL1 Ensembl NCBI GeneCards UniProt Show fit	ASXL transcriptional regulator 1
chr1_-_205356568 Show fit	0.89	ENST00000460687.5	KLHDC8A Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 8A
chr10_-_34815257 Show fit	0.89	ENST00000374789.8 ENST00000374788.8 ENST00000346874.9 ENST00000374794.8 ENST00000350537.9 ENST00000374790.8 ENST00000374776.6 ENST00000374773.6 ENST00000545260.5 ENST00000545693.5 ENST00000340077.9	PARD3 Ensembl NCBI GeneCards UniProt Show fit	par-3 family cell polarity regulator
chr17_+_76376581 Show fit	0.88	ENST00000591651.5 ENST00000545180.5	SPHK1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr2_+_233617626 Show fit	0.86	ENST00000373450.5	UGT1A8 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A8
chr19_+_49474561 Show fit	0.85	ENST00000594009.5 ENST00000595510.1 ENST00000595815.1	FLT3LG Ensembl NCBI GeneCards UniProt Show fit ENSG00000273189.1 Ensembl NCBI GeneCards UniProt Show fit	fms related receptor tyrosine kinase 3 ligand novel transcript
chr3_-_45958654 Show fit	0.84	ENST00000438446.1	FYCO1 Ensembl NCBI GeneCards UniProt Show fit	FYVE and coiled-coil domain autophagy adaptor 1
chr3_-_44510602 Show fit	0.84	ENST00000436261.6	ZNF852 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 852
chr11_+_128693887 Show fit	0.83	ENST00000281428.12	FLI1 Ensembl NCBI GeneCards UniProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr1_+_181033887 Show fit	0.83	ENST00000684662.1 ENST00000434571.7 ENST00000367580.6 ENST00000617803.5 ENST00000683652.1 ENST00000367579.7 ENST00000282990.10	MR1 Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I-related
chr14_+_24136152 Show fit	0.83	ENST00000559123.5 ENST00000206451.11 ENST00000382708.7 ENST00000561435.5	PSME1 Ensembl NCBI GeneCards UniProt Show fit	proteasome activator subunit 1
chr7_-_41700583 Show fit	0.82	ENST00000442711.1	INHBA Ensembl NCBI GeneCards UniProt Show fit	inhibin subunit beta A
chr18_-_55423757 Show fit	0.82	ENST00000675707.1	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr1_-_205356864 Show fit	0.81	ENST00000491471.5	KLHDC8A Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 8A
chr5_+_73813518 Show fit	0.80	ENST00000296799.8	ARHGEF28 Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 28
chr4_+_141636563 Show fit	0.79	ENST00000320650.9 ENST00000296545.11	IL15 Ensembl NCBI GeneCards UniProt Show fit	interleukin 15
chr11_+_128694052 Show fit	0.76	ENST00000527786.7 ENST00000534087.3	FLI1 Ensembl NCBI GeneCards UniProt Show fit	Fli-1 proto-oncogene, ETS transcription factor
chr22_+_41301514 Show fit	0.75	ENST00000352645.5	ZC3H7B Ensembl NCBI GeneCards UniProt Show fit	zinc finger CCCH-type containing 7B
chr16_-_67936808 Show fit	0.75	ENST00000358514.9	PSMB10 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 10
chr1_-_161044941 Show fit	0.74	ENST00000368020.5	USF1 Ensembl NCBI GeneCards UniProt Show fit	upstream transcription factor 1
chr11_-_47715344 Show fit	0.73	ENST00000525123.6 ENST00000528244.5 ENST00000532595.5 ENST00000529154.5 ENST00000530969.1	AGBL2 Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein like 2
chr9_-_146140 Show fit	0.73	ENST00000475990.5	CBWD1 Ensembl NCBI GeneCards UniProt Show fit	COBW domain containing 1
chr9_+_137618986 Show fit	0.72	ENST00000462484.5 ENST00000630754.2 ENST00000460843.6 ENST00000626216.2 ENST00000629335.2	EHMT1 Ensembl NCBI GeneCards UniProt Show fit	euchromatic histone lysine methyltransferase 1
chr4_-_145938775 Show fit	0.69	ENST00000508784.6	ZNF827 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 827
chr1_-_205357033 Show fit	0.68	ENST00000367156.7 ENST00000606887.5 ENST00000539253.5 ENST00000607173.5	KLHDC8A Ensembl NCBI GeneCards UniProt Show fit	kelch domain containing 8A
chr10_+_120851341 Show fit	0.68	ENST00000263461.11	WDR11 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 11
chr10_+_60778331 Show fit	0.64	ENST00000519078.6 ENST00000316629.8 ENST00000395284.8	CDK1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr14_-_23010122 Show fit	0.64	ENST00000397377.5 ENST00000397379.7 ENST00000341470.8 ENST00000555998.5 ENST00000299088.11 ENST00000397376.6 ENST00000553675.5 ENST00000553931.5 ENST00000555575.5 ENST00000553958.5 ENST00000555098.5 ENST00000556419.5 ENST00000553606.5 ENST00000554179.5 ENST00000397382.8	C14orf93 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 93
chr10_+_60778490 Show fit	0.63	ENST00000448257.6 ENST00000614696.4	CDK1 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 1
chr3_-_71493500 Show fit	0.62	ENST00000648380.1 ENST00000650295.1	FOXP1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box P1
chr6_+_57317602 Show fit	0.61	ENST00000274891.10 ENST00000671770.1 ENST00000672107.1 ENST00000615550.5	PRIM2 Ensembl NCBI GeneCards UniProt Show fit	DNA primase subunit 2
chr8_-_56074144 Show fit	0.60	ENST00000618656.2	RPS20 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S20
chr7_-_122886706 Show fit	0.58	ENST00000313070.11 ENST00000334010.11 ENST00000615869.4	CADPS2 Ensembl NCBI GeneCards UniProt Show fit	calcium dependent secretion activator 2
chr4_+_141636611 Show fit	0.56	ENST00000514653.5	IL15 Ensembl NCBI GeneCards UniProt Show fit	interleukin 15
chr2_-_230219944 Show fit	0.56	ENST00000455674.2 ENST00000392048.7 ENST00000258381.11 ENST00000358662.9 ENST00000258382.10	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr6_+_32844108 Show fit	0.52	ENST00000458296.2 ENST00000413039.6 ENST00000412095.1 ENST00000395330.5	PSMB8-AS1 Ensembl NCBI GeneCards UniProt Show fit PSMB9 Ensembl NCBI GeneCards UniProt Show fit	PSMB8 antisense RNA 1 (head to head) proteasome 20S subunit beta 9
chr5_+_50666950 Show fit	0.50	ENST00000513738.5 ENST00000503665.5 ENST00000514067.6 ENST00000503046.5	PARP8 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr7_-_111784448 Show fit	0.49	ENST00000450156.6	DOCK4 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 4
chr9_+_2159672 Show fit	0.49	ENST00000634343.1	SMARCA2 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_223837484 Show fit	0.49	ENST00000446015.6 ENST00000409375.1	AP1S3 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 1 subunit sigma 3
chr20_+_58651785 Show fit	0.48	ENST00000358029.8	STX16 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 16
chr6_-_32838727 Show fit	0.46	ENST00000652259.1 ENST00000374897.4 ENST00000620123.4 ENST00000452392.2	TAP2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000250264.1 Ensembl NCBI GeneCards UniProt Show fit	transporter 2, ATP binding cassette subfamily B member novel protein, TAP2-HLA-DOB readthrough
chr8_+_39913881 Show fit	0.45	ENST00000518237.6	IDO1 Ensembl NCBI GeneCards UniProt Show fit	indoleamine 2,3-dioxygenase 1
chr10_-_80289647 Show fit	0.45	ENST00000372213.8	MAT1A Ensembl NCBI GeneCards UniProt Show fit	methionine adenosyltransferase 1A
chr9_-_114806031 Show fit	0.44	ENST00000374045.5	TNFSF15 Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 15
chr6_+_32854179 Show fit	0.44	ENST00000374859.3	PSMB9 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr13_+_108269629 Show fit	0.43	ENST00000430559.5 ENST00000375887.9	TNFSF13B Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 13b
chr8_-_23682889 Show fit	0.43	ENST00000523261.1 ENST00000380871.5	NKX3-1 Ensembl NCBI GeneCards UniProt Show fit	NK3 homeobox 1
chr8_+_95133746 Show fit	0.43	ENST00000315367.4	PLEKHF2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and FYVE domain containing 2
chr7_-_111784406 Show fit	0.42	ENST00000664131.1 ENST00000437129.5	DOCK4 Ensembl NCBI GeneCards UniProt Show fit	dedicator of cytokinesis 4
chr2_+_157257687 Show fit	0.41	ENST00000259056.5	GALNT5 Ensembl NCBI GeneCards UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 5
chr7_-_78771108 Show fit	0.41	ENST00000626691.2	MAGI2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_24442241 Show fit	0.39	ENST00000555355.5 ENST00000553343.5 ENST00000556523.1 ENST00000556249.1 ENST00000538105.6 ENST00000555225.5	SDR39U1 Ensembl NCBI GeneCards UniProt Show fit	short chain dehydrogenase/reductase family 39U member 1
chr19_-_6670151 Show fit	0.37	ENST00000675206.1	TNFSF14 Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 14
chrX_-_134796256 Show fit	0.35	ENST00000486347.5	PABIR2 Ensembl NCBI GeneCards UniProt Show fit	PABIR family member 2
chr5_+_77210667 Show fit	0.35	ENST00000264917.10	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr20_+_408030 Show fit	0.34	ENST00000640614.1 ENST00000475269.5	RBCK1 Ensembl NCBI GeneCards UniProt Show fit	RANBP2-type and C3HC4-type zinc finger containing 1
chr17_+_6756035 Show fit	0.33	ENST00000361842.8 ENST00000574907.5	XAF1 Ensembl NCBI GeneCards UniProt Show fit	XIAP associated factor 1
chr5_+_108924585 Show fit	0.33	ENST00000618353.1	FER Ensembl NCBI GeneCards UniProt Show fit	FER tyrosine kinase
chr12_+_50924005 Show fit	0.32	ENST00000550502.1	METTL7A Ensembl NCBI GeneCards UniProt Show fit	methyltransferase like 7A
chr2_-_201643448 Show fit	0.32	ENST00000409883.7	TMEM237 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 237
chr5_+_50666612 Show fit	0.31	ENST00000281631.10	PARP8 Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr14_-_24442765 Show fit	0.31	ENST00000555365.5 ENST00000399395.8 ENST00000553930.5	SDR39U1 Ensembl NCBI GeneCards UniProt Show fit	short chain dehydrogenase/reductase family 39U member 1
chr2_+_233636445 Show fit	0.31	ENST00000344644.9	UGT1A10 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 1 member A10
chr1_+_164630946 Show fit	0.30	ENST00000482110.5	PBX1 Ensembl NCBI GeneCards UniProt Show fit	PBX homeobox 1
chr18_-_55403682 Show fit	0.30	ENST00000564228.5 ENST00000630828.2	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr17_-_4739866 Show fit	0.28	ENST00000574412.6 ENST00000293778.12	CXCL16 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 16
chr6_-_33314202 Show fit	0.28	ENST00000426633.6 ENST00000467025.1	TAPBP Ensembl NCBI GeneCards UniProt Show fit	TAP binding protein
chr5_+_77210881 Show fit	0.28	ENST00000340978.7 ENST00000346042.7 ENST00000342343.8 ENST00000333194.8	PDE8B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 8B
chr7_-_78771058 Show fit	0.27	ENST00000628781.1	MAGI2 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_-_6670117 Show fit	0.27	ENST00000245912.7	TNFSF14 Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 14
chr15_+_75198866 Show fit	0.27	ENST00000562637.1 ENST00000360639.6	C15orf39 Ensembl NCBI GeneCards UniProt Show fit	chromosome 15 open reading frame 39
chr13_+_30735523 Show fit	0.26	ENST00000380490.5	ALOX5AP Ensembl NCBI GeneCards UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr17_-_59155235 Show fit	0.26	ENST00000581068.5	SKA2 Ensembl NCBI GeneCards UniProt Show fit	spindle and kinetochore associated complex subunit 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.8	GO:0035759	mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
2.4	16.6	GO:0030421	defecation(GO:0030421)
2.3	11.5	GO:0097403	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
2.2	11.0	GO:1902228	mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.7	5.0	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.3	5.3	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
1.3	5.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.3	8.9	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
1.3	3.8	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
1.2	6.2	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
1.1	5.6	GO:1901202	negative regulation of extracellular matrix assembly(GO:1901202)
1.1	3.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.8	2.4	GO:0021757	caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.8	6.0	GO:0070383	DNA cytosine deamination(GO:0070383)
0.8	2.3	GO:0045062	extrathymic T cell selection(GO:0045062)
0.7	2.9	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7	2.9	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6	4.7	GO:0061113	pancreas morphogenesis(GO:0061113)
0.6	3.4	GO:0008218	bioluminescence(GO:0008218)
0.6	2.8	GO:0034344	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.6	3.3	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5	4.9	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.5	2.1	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.5	1.5	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.5	9.9	GO:0006069	ethanol oxidation(GO:0006069)
0.4	1.3	GO:1901877	regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.4	4.1	GO:0070842	aggresome assembly(GO:0070842)
0.4	1.2	GO:1990654	sebum secreting cell proliferation(GO:1990654)
0.4	4.0	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.3	0.9	GO:0046521	sphingoid catabolic process(GO:0046521)
0.3	1.8	GO:0009804	coumarin metabolic process(GO:0009804)
0.2	8.7	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2	6.4	GO:1900116	extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	2.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.2	0.9	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2	2.6	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.2	1.6	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.9	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.2	3.4	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.2	0.9	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.2	1.7	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.2	1.8	GO:0002051	osteoblast fate commitment(GO:0002051)
0.2	1.3	GO:0090166	Golgi disassembly(GO:0090166)
0.2	2.8	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.2	2.6	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2	0.5	GO:0002428	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.1	2.9	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.9	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	1.6	GO:0070970	interleukin-2 secretion(GO:0070970)
0.1	0.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	1.7	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.1	1.9	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	1.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.1	0.5	GO:0036269	swimming behavior(GO:0036269)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	1.6	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	0.7	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1	0.7	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.1	1.6	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.1	1.4	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.1	2.4	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.6	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.4	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.1	0.3	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1	2.9	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	0.8	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.1	2.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	1.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.7	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.7	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	1.6	GO:0035855	megakaryocyte development(GO:0035855)
0.1	3.9	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.7	GO:0060992	response to fungicide(GO:0060992)
0.0	5.0	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.6	GO:1990504	dense core granule exocytosis(GO:1990504)
0.0	2.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.5	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	4.9	GO:0045638	negative regulation of myeloid cell differentiation(GO:0045638)
0.0	5.7	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.6	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0	1.9	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	1.0	GO:2000651	positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0	0.3	GO:2001300	lipoxin metabolic process(GO:2001300)
0.0	0.4	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	2.0	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	2.3	GO:0071357	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	1.1	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.6	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.1	GO:0050822	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	3.4	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.0	8.6	GO:0006936	muscle contraction(GO:0006936)
0.0	0.9	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	1.3	GO:0042632	cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0	0.9	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	1.6	GO:0001942	hair follicle development(GO:0001942)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	11.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
1.3	5.3	GO:0005588	collagen type V trimer(GO:0005588)
1.1	3.2	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.1	4.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.0	2.9	GO:1990622	CHOP-ATF3 complex(GO:1990622)
0.8	3.0	GO:0008537	proteasome activator complex(GO:0008537)
0.6	8.6	GO:0030478	actin cap(GO:0030478)
0.6	1.7	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4	2.9	GO:1990111	spermatoproteasome complex(GO:1990111)
0.3	1.3	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.3	4.9	GO:0030870	Mre11 complex(GO:0030870)
0.2	0.9	GO:0035517	PR-DUB complex(GO:0035517)
0.2	2.6	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.2	1.6	GO:0000938	GARP complex(GO:0000938)
0.2	1.4	GO:0097165	nuclear stress granule(GO:0097165)
0.1	5.3	GO:0042101	T cell receptor complex(GO:0042101)
0.1	8.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	2.3	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	2.8	GO:0036020	endolysosome membrane(GO:0036020)
0.1	0.6	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.8	GO:0071797	LUBAC complex(GO:0071797)
0.1	2.4	GO:0005922	connexon complex(GO:0005922)
0.1	0.8	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.9	GO:0033269	internode region of axon(GO:0033269)
0.1	0.5	GO:0042825	TAP complex(GO:0042825)
0.1	14.2	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	0.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.1	0.7	GO:0016589	NURF complex(GO:0016589)
0.1	0.2	GO:0016590	ACF complex(GO:0016590)
0.1	1.8	GO:0071141	SMAD protein complex(GO:0071141)
0.1	4.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	1.6	GO:0005581	collagen trimer(GO:0005581)
0.0	0.7	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	3.0	GO:0016235	aggresome(GO:0016235)
0.0	1.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.7	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	20.4	GO:0031965	nuclear membrane(GO:0031965)
0.0	3.4	GO:0034707	chloride channel complex(GO:0034707)
0.0	3.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	4.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	1.9	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	3.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	5.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	5.0	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.3	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.6	GO:0010369	chromocenter(GO:0010369)
0.0	2.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	34.5	GO:0005615	extracellular space(GO:0005615)
0.0	6.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	2.3	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.5	GO:0071564	npBAF complex(GO:0071564)
0.0	1.8	GO:0000123	histone acetyltransferase complex(GO:0000123)
0.0	0.9	GO:0032420	stereocilium(GO:0032420)
0.0	1.6	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.5	GO:0031985	Golgi cisterna(GO:0031985)
0.0	1.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.4	GO:0042007	interleukin-18 binding(GO:0042007)
1.4	11.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
1.3	5.0	GO:0015375	glycine:sodium symporter activity(GO:0015375)
1.1	9.9	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.6	8.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.4	2.2	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.4	11.5	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.4	4.9	GO:0070087	chromo shadow domain binding(GO:0070087)
0.4	2.6	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4	3.2	GO:0034711	inhibin binding(GO:0034711)
0.4	5.3	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3	3.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.3	2.9	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.3	3.8	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.3	2.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.3	12.1	GO:0008009	chemokine activity(GO:0008009)
0.3	8.6	GO:0005523	tropomyosin binding(GO:0005523)
0.3	2.4	GO:0086075	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.3	5.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	2.0	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.2	1.7	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2	1.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.2	2.9	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2	3.8	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.1	2.0	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.1	2.6	GO:0008417	fucosyltransferase activity(GO:0008417)
0.1	0.6	GO:0003896	DNA primase activity(GO:0003896)
0.1	4.1	GO:0070628	proteasome binding(GO:0070628)
0.1	0.5	GO:0033754	indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1	0.9	GO:0008481	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	0.5	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.1	3.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.8	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.3	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	3.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.6	GO:0050700	CARD domain binding(GO:0050700)
0.1	3.9	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.9	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.7	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	0.7	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.4	GO:0004882	androgen receptor activity(GO:0004882)
0.1	19.5	GO:0008201	heparin binding(GO:0008201)
0.1	1.9	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	1.4	GO:0017091	AU-rich element binding(GO:0017091)
0.1	11.7	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	0.8	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	2.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	1.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	2.3	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	1.7	GO:0001972	retinoic acid binding(GO:0001972)
0.0	5.6	GO:0005518	collagen binding(GO:0005518)
0.0	0.9	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	3.0	GO:0050681	androgen receptor binding(GO:0050681)
0.0	3.3	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	1.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	1.8	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	16.1	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	2.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	5.0	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	1.1	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	1.8	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	1.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	1.0	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.7	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	3.4	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	2.8	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	2.7	GO:0005319	lipid transporter activity(GO:0005319)
0.0	2.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.5	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	2.1	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.6	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	1.9	GO:0008565	protein transporter activity(GO:0008565)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	25.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	11.0	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	5.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	5.0	PID ALK1 PATHWAY	ALK1 signaling events
0.1	5.6	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	1.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	3.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	5.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	5.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.1	2.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	6.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.9	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	1.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	10.8	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	2.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	1.6	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.8	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.9	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	1.7	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	9.9	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.4	11.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3	20.5	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	3.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	2.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2	2.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	5.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	8.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	3.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	2.9	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.1	1.3	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.1	1.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	9.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	5.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	1.8	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	2.9	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	4.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	5.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.5	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	1.6	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	1.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.0	2.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	4.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	2.4	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	1.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	5.2	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	2.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.7	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	1.2	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	1.2	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism

Results for PRDM1

Z-value: 1.93

Motif logo

Transcription factors associated with PRDM1

Activity-expression correlation:

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: