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Illumina Body Map 2 (GSE30611)

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Results for PRDM14

Z-value: 0.53

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
ENSG00000147596.4 PR/SET domain 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM14hg38_v1_chr8_-_70071226_700712580.621.3e-04Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_43847142 1.75 ENST00000377203.8
ENST00000539718.5
ENST00000588884.1
ENST00000293396.12
ENST00000586233.5
CD300 molecule like family member g
chr17_+_43847168 1.69 ENST00000317310.5
CD300 molecule like family member g
chr12_+_54008961 1.07 ENST00000040584.6
homeobox C8
chr17_+_41837817 1.03 ENST00000438813.1
ENST00000293303.5
kelch like family member 10
chrX_-_120077690 0.96 ENST00000371402.5
Rhox homeobox family member 2B
chr5_-_168883333 0.87 ENST00000404867.7
slit guidance ligand 3
chr9_+_84668485 0.87 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chrX_+_120158600 0.80 ENST00000371388.5
Rhox homeobox family member 2
chr1_-_153113507 0.75 ENST00000468739.2
small proline rich protein 2F
chr17_-_48615261 0.73 ENST00000239144.5
homeobox B8
chr17_+_49575828 0.70 ENST00000328741.6
neurexophilin 3
chr17_-_17582417 0.69 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr1_+_155033824 0.67 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DC-STAMP domain containing 1
chr1_+_145927105 0.64 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr1_-_153094521 0.62 ENST00000368750.8
small proline rich protein 2E
chr13_+_108629605 0.58 ENST00000457511.7
myosin XVI
chr1_+_108560031 0.58 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr11_+_85855377 0.57 ENST00000342404.8
coiled-coil domain containing 83
chr11_+_65111845 0.52 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chr11_+_62707668 0.50 ENST00000294117.6
G protein subunit gamma 3
chr1_-_155033778 0.46 ENST00000368424.4
DC-STAMP domain containing 2
chr3_-_134373719 0.43 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
angiomotin like 2
chr1_-_167914089 0.42 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr3_+_156120572 0.39 ENST00000389636.9
ENST00000490337.6
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr16_-_53703810 0.39 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr11_-_62707413 0.36 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr11_-_62707581 0.36 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr3_-_143848442 0.35 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr1_+_26787926 0.33 ENST00000674202.1
ENST00000674222.1
phosphatidylinositol glycan anchor biosynthesis class V
chr7_-_30026617 0.32 ENST00000222803.10
FKBP prolyl isomerase 14
chrX_+_15507302 0.32 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr17_-_2214306 0.31 ENST00000572369.5
SMG6 nonsense mediated mRNA decay factor
chr2_-_144520315 0.31 ENST00000465070.5
ENST00000465308.5
ENST00000636471.1
ENST00000629520.2
ENST00000675069.1
ENST00000636026.2
ENST00000444559.5
zinc finger E-box binding homeobox 2
chr1_+_21570303 0.27 ENST00000374830.2
alkaline phosphatase, biomineralization associated
chr5_-_160685379 0.26 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chr1_+_26788166 0.25 ENST00000374145.6
ENST00000431541.6
ENST00000674273.1
phosphatidylinositol glycan anchor biosynthesis class V
chr7_-_124765753 0.22 ENST00000303921.3
G protein-coupled receptor 37
chr17_-_48614628 0.22 ENST00000576562.1
homeobox B8
chr12_-_48957445 0.21 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ADP ribosylation factor 3
chr22_+_31093358 0.21 ENST00000404574.5
smoothelin
chr16_-_67483541 0.21 ENST00000290953.3
agouti related neuropeptide
chr16_-_53703883 0.18 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr17_-_19748355 0.17 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr19_+_42284483 0.17 ENST00000575354.6
capicua transcriptional repressor
chr15_+_74788542 0.16 ENST00000567571.5
C-terminal Src kinase
chr4_+_4859658 0.16 ENST00000382723.5
msh homeobox 1
chr12_+_55932028 0.16 ENST00000394147.5
ENST00000551156.5
ENST00000553783.5
ENST00000557080.5
ENST00000432422.7
ENST00000556001.5
diacylglycerol kinase alpha
chr9_+_129835442 0.16 ENST00000372429.8
ENST00000315480.9
ENST00000358355.5
ubiquitin specific peptidase 20
chr17_-_19748285 0.15 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr17_-_75779758 0.15 ENST00000592643.5
ENST00000591890.5
ENST00000587171.1
ENST00000254810.8
ENST00000589599.5
H3.3 histone B
chr9_+_97633845 0.15 ENST00000629069.1
nuclear cap binding protein subunit 1
chrX_+_51893533 0.14 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr17_-_17823593 0.13 ENST00000423161.3
sterol regulatory element binding transcription factor 1
chr8_+_109334317 0.13 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr11_-_106022209 0.13 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr11_-_62707331 0.13 ENST00000533982.1
BSCL2 lipid droplet biogenesis associated, seipin
chr4_-_10457385 0.12 ENST00000507515.1
ENST00000326756.4
zinc finger protein 518B
chr10_+_88664439 0.12 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr1_-_6261053 0.12 ENST00000377893.3
G protein-coupled receptor 153
chr2_+_112275588 0.12 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr12_-_48957365 0.10 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr2_-_144521042 0.10 ENST00000637267.2
zinc finger E-box binding homeobox 2
chr1_-_40097216 0.09 ENST00000641083.1
ENST00000641471.1
ENST00000642050.2
ENST00000433473.8
ENST00000439754.6
ENST00000527311.7
ENST00000641319.1
ENST00000449045.7
palmitoyl-protein thioesterase 1
chr19_+_3572777 0.09 ENST00000416526.5
high mobility group 20B
chr12_-_76348404 0.08 ENST00000650064.2
Bardet-Biedl syndrome 10
chr1_+_65264694 0.08 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr11_-_62672255 0.08 ENST00000528862.2
LBH domain containing 1
chr2_-_227379297 0.07 ENST00000304568.4
transmembrane 4 L six family member 20
chr17_+_38717424 0.07 ENST00000615858.1
MLLT6, PHD finger containing
chr1_+_23959109 0.06 ENST00000471915.5
proline rich nuclear receptor coactivator 2
chr5_+_32710630 0.05 ENST00000326958.5
natriuretic peptide receptor 3
chr1_+_50105666 0.05 ENST00000651347.1
ELAV like RNA binding protein 4
chr17_-_19748341 0.04 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr1_+_44808482 0.04 ENST00000450269.5
ENST00000409335.6
BTB domain containing 19
chr11_-_65856944 0.04 ENST00000524553.5
cofilin 1
chr1_+_93079234 0.03 ENST00000540243.5
ENST00000545708.5
metal response element binding transcription factor 2
chr7_+_39950187 0.03 ENST00000181839.10
cyclin dependent kinase 13
chr18_+_59899988 0.03 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr17_+_77453993 0.03 ENST00000592951.5
septin 9
chr3_-_71132099 0.01 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr16_+_53703963 0.01 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr12_-_52573816 0.01 ENST00000549343.5
ENST00000305620.3
keratin 74
chr14_-_53958757 0.01 ENST00000559642.1
bone morphogenetic protein 4
chr1_-_26890237 0.01 ENST00000431781.2
ENST00000374135.9
GPN-loop GTPase 2
chr3_+_36993798 0.01 ENST00000455445.6
ENST00000539477.6
ENST00000435176.5
ENST00000429117.5
ENST00000441265.6
mutL homolog 1
chr3_-_155676363 0.00 ENST00000494598.5
phospholipase C eta 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.3 0.9 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2 1.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1 0.9 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.3 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.7 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.6 GO:0043584 nose development(GO:0043584)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 1.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.6 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 0.7 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.2 0.6 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 0.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 3.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane