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Illumina Body Map 2 (GSE30611)

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Results for PROX1

Z-value: 1.08

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Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
ENSG00000117707.16 prospero homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROX1hg38_v1_chr1_+_213989691_2139897300.057.8e-01Click!

Activity profile of PROX1 motif

Sorted Z-values of PROX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_21712313 2.69 ENST00000390424.2
T cell receptor alpha variable 2
chr14_+_21941122 2.60 ENST00000390441.2
T cell receptor alpha variable 9-2
chr12_+_112791933 2.28 ENST00000551052.5
ENST00000415485.7
rabphilin 3A
chr7_+_142313144 2.22 ENST00000390357.3
T cell receptor beta variable 4-1
chr1_-_160862880 2.09 ENST00000368034.9
CD244 molecule
chr12_+_112791738 1.95 ENST00000389385.9
rabphilin 3A
chr14_+_22320128 1.94 ENST00000390468.1
T cell receptor alpha variable 41
chr1_-_160862700 1.88 ENST00000322302.7
ENST00000368033.7
CD244 molecule
chr5_+_157142933 1.71 ENST00000521769.5
IL2 inducible T cell kinase
chr12_+_57583101 1.66 ENST00000674858.1
ENST00000675433.1
ENST00000674980.1
kinesin family member 5A
chr4_-_170026371 1.58 ENST00000361618.4
ENST00000506764.1
microfibril associated protein 3 like
chr19_+_54850436 1.57 ENST00000326321.7
ENST00000270442.5
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
chr13_-_36214521 1.51 ENST00000379881.8
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr2_-_224569782 1.47 ENST00000409096.5
cullin 3
chr5_-_157575767 1.42 ENST00000257527.9
ADAM metallopeptidase domain 19
chr4_-_170026295 1.37 ENST00000507601.1
ENST00000512698.1
microfibril associated protein 3 like
chr2_-_233013228 1.30 ENST00000264051.8
neuronal guanine nucleotide exchange factor
chr4_-_153759957 1.26 ENST00000508248.1
ENST00000347063.9
ring finger protein 175
chr2_+_230759918 1.22 ENST00000614925.1
calcium binding protein 39
chr2_+_162318884 1.21 ENST00000446271.5
ENST00000429691.6
grancalcin
chr3_-_18445565 1.19 ENST00000415069.5
SATB homeobox 1
chr3_+_9797651 1.17 ENST00000453882.1
ARPC4-TTLL3 readthrough
chr3_+_52410635 1.17 ENST00000327906.8
PHD finger protein 7
chr11_+_73648979 1.16 ENST00000540431.1
pleckstrin homology domain containing B1
chr5_-_157575741 1.14 ENST00000517905.1
ADAM metallopeptidase domain 19
chr14_+_21852457 1.13 ENST00000390435.1
T cell receptor alpha variable 8-3
chr1_+_159800503 1.13 ENST00000536257.5
ENST00000321935.10
Fc receptor like 6
chr7_+_142345412 1.10 ENST00000390392.3
T cell receptor beta variable 4-2
chr3_-_112499457 1.10 ENST00000334529.10
B and T lymphocyte associated
chr4_-_170026333 1.07 ENST00000504999.1
microfibril associated protein 3 like
chr20_+_21126074 1.07 ENST00000619189.5
kizuna centrosomal protein
chr1_-_75932392 1.05 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr1_-_182400660 1.04 ENST00000367565.2
transmembrane epididymal protein 1
chr14_+_21846534 1.03 ENST00000390434.3
T cell receptor alpha variable 8-2
chr10_+_92689946 1.02 ENST00000282728.10
hematopoietically expressed homeobox
chr3_-_131026726 0.98 ENST00000514044.5
ENST00000264992.8
asteroid homolog 1
chr14_+_45135917 0.98 ENST00000267430.10
ENST00000556036.5
ENST00000542564.6
FA complementation group M
chr14_+_73136418 0.97 ENST00000557356.5
ENST00000556864.5
ENST00000556533.5
ENST00000556951.5
ENST00000557293.5
ENST00000553719.5
ENST00000553599.5
ENST00000556011.5
ENST00000394157.7
ENST00000357710.8
ENST00000560005.6
ENST00000555254.5
ENST00000554131.5
ENST00000324501.10
ENST00000557037.5
presenilin 1
chr8_-_144950813 0.96 ENST00000532351.5
ENST00000394909.7
ENST00000276816.8
ENST00000611477.1
zinc finger protein 16
chr16_+_50266530 0.96 ENST00000566433.6
ENST00000394697.7
ENST00000673801.1
adenylate cyclase 7
chr9_+_93058684 0.96 ENST00000617293.4
ENST00000375472.8
ENST00000465709.5
sushi domain containing 3
chr11_-_45286265 0.96 ENST00000020926.8
synaptotagmin 13
chr2_-_151973780 0.95 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
calcium voltage-gated channel auxiliary subunit beta 4
chr1_-_159076742 0.94 ENST00000368130.9
absent in melanoma 2
chr1_-_173207322 0.93 ENST00000281834.4
TNF superfamily member 4
chr2_-_53859929 0.91 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr19_+_51752009 0.90 ENST00000600258.1
formyl peptide receptor 2
chr10_+_32446102 0.90 ENST00000277657.12
ENST00000362006.11
coiled-coil domain containing 7
chr10_+_88759997 0.89 ENST00000404459.2
lipase family member N
chr11_+_65879791 0.89 ENST00000528419.6
ENST00000307886.8
ENST00000526034.2
ENST00000679584.1
ENST00000680443.1
ENST00000680670.1
cathepsin W
chr5_-_157142839 0.89 ENST00000286317.6
ENST00000524219.1
mediator complex subunit 7
hepatitis A virus cellular receptor 2
chr11_-_111879154 0.89 ENST00000260257.9
ferredoxin-fold anticodon binding domain containing 1
chr5_+_174046659 0.88 ENST00000519717.1
neuronal vesicle trafficking associated 2
chr10_-_119536533 0.88 ENST00000392865.5
regulator of G protein signaling 10
chr7_+_66629078 0.88 ENST00000449064.6
ENST00000638540.1
ENST00000640234.1
potassium channel tetramerization domain containing 7
chr3_-_112499358 0.86 ENST00000383680.4
B and T lymphocyte associated
chr1_+_207496229 0.86 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
complement C3b/C4b receptor 1 (Knops blood group)
chr13_-_36214584 0.85 ENST00000317764.6
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr20_+_21125981 0.84 ENST00000619574.4
kizuna centrosomal protein
chr9_+_128504655 0.84 ENST00000683748.1
ENST00000684314.1
ENST00000684331.1
ENST00000684646.1
ENST00000309971.9
ENST00000684139.1
ENST00000372770.4
GLE1 RNA export mediator
chr20_+_21126037 0.84 ENST00000611685.4
ENST00000616848.4
kizuna centrosomal protein
chr3_-_52770856 0.82 ENST00000461689.5
ENST00000535191.5
ENST00000383721.8
ENST00000233027.10
NIMA related kinase 4
chr11_+_73648889 0.82 ENST00000542389.5
pleckstrin homology domain containing B1
chr7_-_91880672 0.80 ENST00000456229.1
ENST00000442961.1
ENST00000406735.6
ENST00000419292.1
ENST00000351870.8
mitochondrial transcription termination factor 1
chr10_-_67696115 0.80 ENST00000433211.7
catenin alpha 3
chr19_+_53395125 0.80 ENST00000396408.8
ENST00000505866.1
ENST00000594030.2
zinc finger protein 765
chr2_+_131105326 0.79 ENST00000438882.6
ENST00000404460.5
pleckstrin homology domain containing B2
chr10_+_35336702 0.79 ENST00000265375.13
ENST00000339497.7
cyclin Y
chr18_-_51218311 0.78 ENST00000591040.2
mex-3 RNA binding family member C
chr18_-_63161848 0.78 ENST00000590515.1
BCL2 apoptosis regulator
chr20_+_21125999 0.77 ENST00000620891.4
kizuna centrosomal protein
chr10_+_110567666 0.77 ENST00000361804.5
structural maintenance of chromosomes 3
chr6_-_25042003 0.76 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr22_-_44498179 0.75 ENST00000341255.4
retrotransposon Gag like 6
chr11_-_83724922 0.74 ENST00000434967.1
ENST00000530800.5
discs large MAGUK scaffold protein 2
chr5_+_146203544 0.73 ENST00000506502.2
novel readthrough transcript
chr6_-_36024493 0.73 ENST00000394602.6
ENST00000355574.6
solute carrier family 26 member 8
chr21_-_25607474 0.72 ENST00000352957.9
ENST00000419219.1
ENST00000307301.11
mitochondrial ribosomal protein L39
chr19_+_9178979 0.71 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr2_+_131105296 0.69 ENST00000628582.2
pleckstrin homology domain containing B2
chr9_+_122371014 0.69 ENST00000362012.7
prostaglandin-endoperoxide synthase 1
chr7_-_143408848 0.69 ENST00000275815.4
EPH receptor A1
chr16_+_11976709 0.69 ENST00000566228.6
sorting nexin 29
chr11_+_1853049 0.67 ENST00000311604.8
lymphocyte specific protein 1
chr10_+_14878848 0.67 ENST00000433779.5
ENST00000378325.7
ENST00000354919.11
ENST00000313519.9
ENST00000420416.1
suppressor of variegation 3-9 homolog 2
chr21_+_34364003 0.67 ENST00000290310.4
potassium voltage-gated channel subfamily E regulatory subunit 2
chr7_+_66629023 0.66 ENST00000639879.1
ENST00000640851.1
potassium channel tetramerization domain containing 7
chr20_+_31440626 0.65 ENST00000376309.4
defensin beta 123
chr22_+_24594781 0.65 ENST00000456869.5
ENST00000411974.5
gamma-glutamyltransferase 1
chr1_+_207496147 0.64 ENST00000400960.7
ENST00000367049.9
complement C3b/C4b receptor 1 (Knops blood group)
chr19_+_52570268 0.64 ENST00000596514.5
ENST00000391785.8
ENST00000301093.6
zinc finger protein 701
chr10_+_45374235 0.63 ENST00000612635.4
arachidonate 5-lipoxygenase
chr10_+_45374204 0.63 ENST00000374391.7
arachidonate 5-lipoxygenase
chr15_+_43517590 0.62 ENST00000300231.6
microtubule associated protein 1A
chr10_+_35336486 0.62 ENST00000374704.8
cyclin Y
chr7_+_66628864 0.62 ENST00000639828.2
ENST00000275532.8
ENST00000640385.1
potassium channel tetramerization domain containing 7
chr3_-_33097100 0.62 ENST00000415454.1
galactosidase beta 1
chr13_-_19782923 0.61 ENST00000338910.9
paraspeckle component 1
chr7_+_23105747 0.60 ENST00000322275.9
ENST00000339077.10
kelch like family member 7
chr3_-_47513677 0.60 ENST00000296149.9
elongator acetyltransferase complex subunit 6
chr4_-_165279679 0.60 ENST00000505354.2
glycerol kinase 3 pseudogene
chr11_+_61955157 0.59 ENST00000526988.1
bestrophin 1
chr19_+_4007714 0.59 ENST00000262971.3
protein inhibitor of activated STAT 4
chr19_-_52857600 0.58 ENST00000596559.5
ENST00000594602.5
ENST00000595646.6
ENST00000597924.5
ENST00000243639.8
zinc finger protein 28
zinc finger protein 468
chrX_+_153179276 0.57 ENST00000356661.7
MAGE family member A1
chr4_+_6782674 0.57 ENST00000307659.6
ENST00000425103.5
KIAA0232
chr4_-_173333672 0.57 ENST00000438704.6
high mobility group box 2
chr5_-_22853320 0.56 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr10_-_30999469 0.56 ENST00000538351.6
zinc finger protein 438
chr19_+_15641280 0.56 ENST00000585846.1
cytochrome P450 family 4 subfamily F member 3
chr5_-_157142745 0.55 ENST00000420343.1
mediator complex subunit 7
chr12_-_117190456 0.55 ENST00000330622.9
ENST00000622495.5
ENST00000427718.6
F-box protein 21
chr7_+_64794415 0.55 ENST00000494380.5
ENST00000440155.6
ENST00000440598.2
ENST00000437743.1
ENST00000307355.12
zinc finger protein 138
chr5_+_50665899 0.54 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr1_+_241532370 0.54 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr3_-_33097132 0.54 ENST00000307363.10
ENST00000307377.12
ENST00000440656.1
ENST00000436768.1
ENST00000342462.5
galactosidase beta 1
transmembrane protein with metallophosphoesterase domain
chr6_+_88047822 0.54 ENST00000237201.2
sperm acrosome associated 1
chr1_+_173868350 0.54 ENST00000427304.5
ENST00000367702.1
zinc finger and BTB domain containing 37
chrX_+_151396566 0.54 ENST00000370361.5
vacuolar ATPase assembly factor VMA21
chr1_+_222644247 0.54 ENST00000340535.11
MIA SH3 domain ER export factor 3
chr2_+_29118195 0.53 ENST00000449202.5
CAP-Gly domain containing linker protein family member 4
chr7_-_102616692 0.53 ENST00000521076.5
ENST00000462172.5
ENST00000522801.5
ENST00000262940.12
ENST00000449970.6
RAS p21 protein activator 4
chr10_-_49762276 0.53 ENST00000374103.9
oxoglutarate dehydrogenase L
chr1_-_54764482 0.53 ENST00000371279.4
prolyl-tRNA synthetase 2, mitochondrial
chr5_+_163503075 0.52 ENST00000280969.9
methionine adenosyltransferase 2B
chr5_+_132556911 0.52 ENST00000651541.1
ENST00000378823.8
ENST00000652485.1
RAD50 double strand break repair protein
chr16_+_31873772 0.52 ENST00000394846.7
ENST00000300870.15
zinc finger protein 267
chr4_-_170027209 0.52 ENST00000393702.7
microfibril associated protein 3 like
chr16_-_66873233 0.51 ENST00000561579.6
NEDD8 activating enzyme E1 subunit 1
chr3_-_33096794 0.51 ENST00000416695.6
ENST00000399402.7
transmembrane protein with metallophosphoesterase domain
galactosidase beta 1
chr6_-_134174853 0.51 ENST00000475719.6
ENST00000367857.9
ENST00000237305.11
serum/glucocorticoid regulated kinase 1
chr12_-_10939263 0.51 ENST00000537503.2
taste 2 receptor member 14
chr11_+_4482646 0.51 ENST00000641528.1
ENST00000642020.1
olfactory receptor family 52 subfamily K member 1
chr6_+_34757473 0.50 ENST00000244520.10
ENST00000374018.5
ENST00000374017.3
small nuclear ribonucleoprotein polypeptide C
chr10_-_43574555 0.50 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr3_-_197298092 0.49 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr11_-_72434330 0.48 ENST00000542555.2
ENST00000535990.5
ENST00000294053.9
ENST00000538039.6
ENST00000340729.9
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr9_+_122371036 0.48 ENST00000619306.5
ENST00000426608.6
ENST00000223423.8
prostaglandin-endoperoxide synthase 1
chr1_+_207053229 0.47 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr1_-_27914513 0.47 ENST00000313433.11
ENST00000373912.8
ENST00000444045.1
replication protein A2
chr13_+_113044632 0.47 ENST00000397021.5
MCF.2 cell line derived transforming sequence like
chr5_+_146203593 0.46 ENST00000265271.7
RNA binding motif protein 27
chr17_+_16690223 0.46 ENST00000340621.9
ENST00000399273.5
ENST00000456009.4
ENST00000360524.12
coiled-coil domain containing 144A
chr15_+_38454103 0.45 ENST00000397609.6
ENST00000491535.5
family with sequence similarity 98 member B
chr3_-_132035004 0.44 ENST00000429747.6
copine 4
chr14_+_22314435 0.44 ENST00000390467.3
T cell receptor alpha variable 40
chrX_-_52517213 0.44 ENST00000375616.5
X antigen family member 1B
chr19_-_19643597 0.44 ENST00000587205.1
ENST00000203556.9
GEM interacting protein
chr11_-_30016945 0.44 ENST00000328224.7
potassium voltage-gated channel subfamily A member 4
chr6_-_8102046 0.44 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr1_-_202341926 0.43 ENST00000646651.1
ubiquitin conjugating enzyme E2 T
chr7_+_64794388 0.43 ENST00000359735.7
zinc finger protein 138
chrY_+_20756103 0.43 ENST00000629237.2
ribosomal protein S4 Y-linked 2
chr13_-_77027181 0.43 ENST00000417323.1
F-box and leucine rich repeat protein 3
chr10_+_16436943 0.43 ENST00000423462.6
ENST00000378000.5
phosphotriesterase related
chr1_+_10399376 0.43 ENST00000465632.5
ENST00000460189.1
phosphogluconate dehydrogenase
chr7_-_102517755 0.42 ENST00000306682.6
ENST00000465829.6
ENST00000541662.5
RAS p21 protein activator 4B
chr3_-_196287649 0.42 ENST00000441879.5
ENST00000292823.6
ENST00000431016.6
ENST00000411591.5
phosphate cytidylyltransferase 1, choline, alpha
chr11_-_83286328 0.42 ENST00000525503.5
coiled-coil domain containing 90B
chr7_+_92528769 0.41 ENST00000481551.5
ENST00000265732.10
ENST00000496410.1
RNA binding motif protein 48
chr19_-_56824314 0.41 ENST00000593931.1
zinc finger imprinted 2
chr6_-_89819699 0.41 ENST00000439638.1
ENST00000629399.2
ENST00000369393.8
midasin AAA ATPase 1
chrX_+_147981324 0.41 ENST00000370467.8
FMR1 neighbor
chr19_-_44304968 0.41 ENST00000591609.1
ENST00000589799.5
ENST00000291182.9
ENST00000650576.1
ENST00000589248.5
zinc finger protein 235
chr1_-_27914717 0.41 ENST00000373909.7
replication protein A2
chr2_+_86942118 0.40 ENST00000641458.2
RANBP2 like and GRIP domain containing 1
chr1_+_161749762 0.40 ENST00000367943.5
dual specificity phosphatase 12
chr11_-_36289408 0.40 ENST00000263401.10
ENST00000532705.1
ENST00000452374.6
COMM domain containing 9
chr6_+_116877236 0.40 ENST00000332958.3
regulatory factor X6
chr2_-_106468326 0.39 ENST00000304514.11
ENST00000409886.4
RANBP2 like and GRIP domain containing 3
chr3_-_11846772 0.38 ENST00000455809.5
ENST00000444133.6
ENST00000273037.9
ENST00000630288.1
TAM41 mitochondrial translocator assembly and maintenance homolog
chr11_-_127000762 0.38 ENST00000525144.7
kirre like nephrin family adhesion molecule 3
chr11_+_28110275 0.38 ENST00000303459.10
ENST00000634762.1
ENST00000634721.1
methyltransferase like 15
chr7_+_100177897 0.38 ENST00000317296.9
ENST00000615138.5
ENST00000620100.5
ENST00000422690.5
ENST00000439782.1
stromal antigen 3
chr13_+_43023577 0.38 ENST00000379221.4
DnaJ heat shock protein family (Hsp40) member C15
chr2_-_151973991 0.37 ENST00000534999.6
ENST00000637217.1
ENST00000360283.11
calcium voltage-gated channel auxiliary subunit beta 4
chr4_-_127965930 0.37 ENST00000641447.1
ENST00000296468.8
ENST00000641134.1
ENST00000641147.1
ENST00000641178.1
major facilitator superfamily domain containing 8
chr8_-_144605699 0.37 ENST00000377307.6
ENST00000276826.5
Rho GTPase activating protein 39
chr2_+_17754116 0.37 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chrX_+_12137409 0.37 ENST00000672010.1
FERM and PDZ domain containing 4
chr10_+_16436996 0.37 ENST00000535784.7
phosphotriesterase related
chr1_+_241532121 0.36 ENST00000366558.7
kynurenine 3-monooxygenase
chr16_+_31713231 0.36 ENST00000539915.5
ENST00000316491.13
ENST00000398696.3
ENST00000534369.1
ENST00000530881.5
ENST00000529515.1
zinc finger protein 720
chr18_+_13465009 0.36 ENST00000593236.1
ENST00000678400.1
low density lipoprotein receptor class A domain containing 4
chr17_-_81959769 0.36 ENST00000477214.5
notum, palmitoleoyl-protein carboxylesterase
chr10_-_97185507 0.35 ENST00000314867.9
slit guidance ligand 1
chr11_-_72434626 0.35 ENST00000646117.1
ENST00000437826.6
caseinolytic mitochondrial matrix peptidase chaperone subunit B
chr19_+_41376560 0.35 ENST00000436170.6
transmembrane protein 91
chr7_-_37448845 0.35 ENST00000310758.9
engulfment and cell motility 1
chr11_+_93661641 0.35 ENST00000325212.11
centrosomal protein 295
chr16_-_23596277 0.34 ENST00000562133.5
ENST00000570319.5
ENST00000007516.8
NADH:ubiquinone oxidoreductase subunit AB1
chr3_+_196712298 0.34 ENST00000392391.9
ENST00000296333.10
phosphatidylinositol glycan anchor biosynthesis class X
chr9_+_122370523 0.34 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr5_+_172958729 0.34 ENST00000519974.5
ENST00000521476.5
ribosomal protein L26 like 1
chr9_-_83921405 0.33 ENST00000297814.7
ENST00000334204.6
ENST00000413982.5
kinesin family member 27
chr12_+_123458092 0.33 ENST00000526639.3
small nuclear ribonucleoprotein U11/U12 subunit 35
chr1_+_179293714 0.33 ENST00000540564.5
ENST00000539888.5
sterol O-acyltransferase 1
chr4_-_68349750 0.33 ENST00000579690.5
YTH domain containing 1
chr8_-_134639808 0.32 ENST00000522257.5
zinc finger and AT-hook domain containing
chrX_-_152753840 0.32 ENST00000617505.1
ENST00000684311.1
ENST00000617846.4
ENST00000595583.5
ENST00000620710.4
ENST00000611557.4
ENST00000623806.3
ENST00000623438.3
ENST00000598543.5
ENST00000611674.4
MAGE family member A2

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.5 1.5 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.4 1.7 GO:0051413 response to cortisone(GO:0051413)
0.4 1.7 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.4 1.5 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 1.0 GO:0061011 hepatic duct development(GO:0061011)
0.3 1.3 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.3 0.9 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.3 1.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.3 0.9 GO:1901257 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.2 0.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 1.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.2 0.8 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.7 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.9 GO:0070269 pyroptosis(GO:0070269)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.8 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.1 0.4 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.6 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.8 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.8 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.4 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.1 0.3 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 1.2 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.6 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.1 0.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.3 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 6.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 1.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.8 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.3 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.1 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.4 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 1.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.0 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 2.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.5 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 4.8 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.0 GO:0007602 phototransduction(GO:0007602)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 2.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 2.4 GO:0048477 oogenesis(GO:0048477)
0.0 1.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.0 1.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0050915 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 4.0 GO:0007051 spindle organization(GO:0007051)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.2 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 0.9 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.2 1.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 0.9 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.5 GO:0005827 polar microtubule(GO:0005827)
0.1 2.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.8 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 1.0 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 0.9 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 2.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.4 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 1.3 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.4 1.5 GO:0031208 POZ domain binding(GO:0031208)
0.3 1.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 5.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.7 GO:0016936 galactoside binding(GO:0016936)
0.2 0.8 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 0.6 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.6 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.8 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.6 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.4 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.6 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 4.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.7 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.3 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.6 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.4 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 2.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0030379 neurotensin receptor activity, non-G-protein coupled(GO:0030379)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 1.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 1.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 1.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 1.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 2.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis