Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for PRRX1_ALX4_PHOX2A

Z-value: 0.89

Motif logo

logo of logo of logo of

Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
PRRX1
ENSG00000116132.12 paired related homeobox 1
ALX4
ENSG00000052850.8 ALX homeobox 4
PHOX2A
ENSG00000165462.5 paired like homeobox 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PHOX2Ahg38_v1_chr11_-_72244166_72244184-0.494.4e-03Click!
PRRX1hg38_v1_chr1_+_170663917_170663943-0.115.7e-01Click!
ALX4hg38_v1_chr11_-_44310126_44310152-0.096.4e-01Click!

Activity profile of PRRX1_ALX4_PHOX2A motif

Sorted Z-values of PRRX1_ALX4_PHOX2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_36606355 6.16 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr6_+_121437378 6.11 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr8_-_26867267 3.47 ENST00000380573.4
ADRA1A
adrenoceptor alpha 1A
chr3_-_195583931 3.46 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
APOD
apolipoprotein D
chr10_+_68106109 3.37 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr15_+_51377247 3.27 ENST00000396399.6
GLDN
gliomedin
chr6_+_54099538 3.17 ENST00000447836.6
MLIP
muscular LMNA interacting protein
chr6_+_54099565 2.93 ENST00000511678.5
MLIP
muscular LMNA interacting protein
chr15_+_51377410 2.90 ENST00000612989.1
GLDN
gliomedin
chr3_-_165196369 2.90 ENST00000475390.2
SLITRK3
SLIT and NTRK like family member 3
chr14_+_94612383 2.75 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
SERPINA3
serpin family A member 3
chr11_+_108116688 2.64 ENST00000672284.1
ACAT1
acetyl-CoA acetyltransferase 1
chr3_-_165196689 2.56 ENST00000241274.3
SLITRK3
SLIT and NTRK like family member 3
chr4_-_175891691 2.37 ENST00000507540.1
GPM6A
glycoprotein M6A
chr2_+_161416273 2.35 ENST00000389554.8
TBR1
T-box brain transcription factor 1
chr4_+_154563003 2.30 ENST00000302068.9
ENST00000509493.1
FGB
fibrinogen beta chain
chr15_+_51377315 2.25 ENST00000558426.5
GLDN
gliomedin
chr6_-_75363003 1.91 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr2_+_165294031 1.84 ENST00000283256.10
SCN2A
sodium voltage-gated channel alpha subunit 2
chr17_+_55264952 1.80 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr13_-_101416441 1.71 ENST00000675332.1
ENST00000676315.1
ENST00000251127.11
NALCN
sodium leak channel, non-selective
chr18_-_24311495 1.65 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr4_-_175812746 1.63 ENST00000393658.6
GPM6A
glycoprotein M6A
chr10_-_20897288 1.59 ENST00000377122.9
NEBL
nebulette
chr11_+_75100531 1.56 ENST00000531713.5
SLCO2B1
solute carrier organic anion transporter family member 2B1
chr6_+_63576864 1.56 ENST00000627002.1
PTP4A1
protein tyrosine phosphatase 4A1
chrX_-_15314543 1.50 ENST00000344384.8
ASB11
ankyrin repeat and SOCS box containing 11
chr7_-_83162857 1.50 ENST00000333891.14
PCLO
piccolo presynaptic cytomatrix protein
chr1_-_93681829 1.45 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr2_-_174764436 1.40 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr9_+_121567057 1.39 ENST00000394340.7
ENST00000436835.5
ENST00000259371.6
DAB2IP
DAB2 interacting protein
chr12_+_12725897 1.39 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr18_+_23134561 1.37 ENST00000400473.6
CABLES1
Cdk5 and Abl enzyme substrate 1
chr5_+_141364153 1.37 ENST00000518069.2
PCDHGA5
protocadherin gamma subfamily A, 5
chr16_-_75726490 1.32 ENST00000640559.2
CPHXL
cytoplasmic polyadenylated homeobox like
chr16_-_57946602 1.31 ENST00000564654.1
CNGB1
cyclic nucleotide gated channel subunit beta 1
chr6_+_54018910 1.28 ENST00000514921.5
ENST00000274897.9
ENST00000370877.6
MLIP
muscular LMNA interacting protein
chr7_-_108243234 1.25 ENST00000417701.5
NRCAM
neuronal cell adhesion molecule
chr5_-_116536458 1.25 ENST00000510263.5
SEMA6A
semaphorin 6A
chr1_+_207325629 1.24 ENST00000618707.2
CD55
CD55 molecule (Cromer blood group)
chr21_-_34526850 1.24 ENST00000481448.5
ENST00000381132.6
RCAN1
regulator of calcineurin 1
chr2_-_201739205 1.23 ENST00000681558.1
ENST00000681495.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr8_-_85341705 1.23 ENST00000517618.5
CA1
carbonic anhydrase 1
chr11_-_40294089 1.22 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr5_-_116536428 1.21 ENST00000515009.5
SEMA6A
semaphorin 6A
chr1_+_177170916 1.18 ENST00000361539.5
BRINP2
BMP/retinoic acid inducible neural specific 2
chr5_+_141343818 1.18 ENST00000619750.1
ENST00000253812.8
PCDHGA3
protocadherin gamma subfamily A, 3
chr6_+_55327469 1.18 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr5_+_141338753 1.17 ENST00000528330.2
ENST00000394576.3
PCDHGA2
protocadherin gamma subfamily A, 2
chr1_+_50103903 1.16 ENST00000371827.5
ELAVL4
ELAV like RNA binding protein 4
chr16_-_71577082 1.15 ENST00000355962.5
TAT
tyrosine aminotransferase
chr18_-_55322215 1.13 ENST00000457482.7
TCF4
transcription factor 4
chr3_+_160225409 1.11 ENST00000326474.5
C3orf80
chromosome 3 open reading frame 80
chr13_-_46897021 1.09 ENST00000542664.4
ENST00000543956.5
HTR2A
5-hydroxytryptamine receptor 2A
chr3_-_12545499 1.06 ENST00000564146.4
MKRN2OS
MKRN2 opposite strand
chr7_-_83162899 1.06 ENST00000423517.6
PCLO
piccolo presynaptic cytomatrix protein
chr14_+_20239286 1.04 ENST00000641082.1
OR11H4
olfactory receptor family 11 subfamily H member 4
chr2_-_174764407 1.03 ENST00000409219.5
ENST00000409542.5
CHRNA1
cholinergic receptor nicotinic alpha 1 subunit
chr6_-_134317905 1.01 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_9791586 0.98 ENST00000571134.2
DHRS7C
dehydrogenase/reductase 7C
chrX_+_77910656 0.98 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr16_+_7332744 0.95 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RBFOX1
RNA binding fox-1 homolog 1
chr3_-_196515315 0.94 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr19_-_7021431 0.94 ENST00000636986.2
ENST00000637800.1
MBD3L2B
methyl-CpG binding domain protein 3 like 2B
chr18_-_55321986 0.93 ENST00000570287.6
TCF4
transcription factor 4
chr6_-_138512493 0.92 ENST00000533765.1
NHSL1
NHS like 1
chr11_+_49028823 0.91 ENST00000332682.9
TRIM49B
tripartite motif containing 49B
chr1_+_42380772 0.90 ENST00000431473.4
ENST00000410070.6
RIMKLA
ribosomal modification protein rimK like family member A
chr8_-_17895403 0.89 ENST00000381840.5
ENST00000398054.5
FGL1
fibrinogen like 1
chr7_-_111392915 0.89 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr2_-_55269038 0.88 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr16_+_6483728 0.88 ENST00000675459.1
ENST00000551752.5
RBFOX1
RNA binding fox-1 homolog 1
chr19_-_11346228 0.88 ENST00000588560.5
ENST00000592952.5
TMEM205
transmembrane protein 205
chr21_-_34526815 0.88 ENST00000492600.1
RCAN1
regulator of calcineurin 1
chr7_+_90709530 0.87 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr4_-_99435134 0.84 ENST00000476959.5
ENST00000482593.5
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr12_-_7503744 0.82 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr1_+_109213887 0.82 ENST00000234677.7
ENST00000369923.4
SARS1
seryl-tRNA synthetase 1
chr11_+_89924064 0.81 ENST00000623787.3
TRIM49D2
tripartite motif containing 49D2
chr2_+_28778848 0.81 ENST00000418910.1
PPP1CB
protein phosphatase 1 catalytic subunit beta
chr12_-_21775581 0.81 ENST00000537950.1
ENST00000665145.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr12_-_118359166 0.81 ENST00000542902.5
TAOK3
TAO kinase 3
chr12_+_20815672 0.81 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
SLCO1B3
SLCO1B3-SLCO1B7
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr6_+_54018992 0.80 ENST00000509997.5
MLIP
muscular LMNA interacting protein
chr5_+_141364231 0.79 ENST00000611914.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr5_+_173918186 0.79 ENST00000657000.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr5_+_42548043 0.78 ENST00000618088.4
ENST00000612382.4
GHR
growth hormone receptor
chr16_+_6483813 0.78 ENST00000675653.1
RBFOX1
RNA binding fox-1 homolog 1
chr5_+_161850597 0.78 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr8_-_85341659 0.75 ENST00000522389.5
CA1
carbonic anhydrase 1
chr4_+_94995796 0.75 ENST00000506363.5
BMPR1B
bone morphogenetic protein receptor type 1B
chr6_+_3258888 0.74 ENST00000380305.4
PSMG4
proteasome assembly chaperone 4
chrX_+_120604199 0.74 ENST00000371315.3
MCTS1
MCTS1 re-initiation and release factor
chr3_+_69936629 0.74 ENST00000394348.2
ENST00000531774.1
MITF
melanocyte inducing transcription factor
chr20_+_33235987 0.72 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr7_+_80626148 0.71 ENST00000428497.5
CD36
CD36 molecule
chr15_+_43800586 0.71 ENST00000442995.4
ENST00000458412.2
HYPK
huntingtin interacting protein K
chr3_+_154121366 0.71 ENST00000465093.6
ENST00000496710.5
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor 26
chr1_+_183805105 0.71 ENST00000360851.4
RGL1
ral guanine nucleotide dissociation stimulator like 1
chr12_-_46825949 0.71 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
SLC38A4
solute carrier family 38 member 4
chr2_+_222860942 0.70 ENST00000392066.7
ENST00000680251.1
ENST00000679541.1
ENST00000679545.1
ENST00000680395.1
ACSL3
acyl-CoA synthetase long chain family member 3
chr8_-_17895487 0.69 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr2_+_222861005 0.69 ENST00000680147.1
ENST00000681009.1
ENST00000679514.1
ENST00000357430.8
ACSL3
acyl-CoA synthetase long chain family member 3
chr19_-_11346259 0.69 ENST00000590788.1
ENST00000354882.10
ENST00000586590.5
ENST00000589555.5
ENST00000586956.5
ENST00000593256.6
ENST00000447337.5
ENST00000591677.5
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr12_-_16608183 0.68 ENST00000354662.5
ENST00000538051.5
LMO3
LIM domain only 3
chr8_-_61689768 0.68 ENST00000517847.6
ENST00000389204.8
ENST00000517661.5
ENST00000517903.5
ENST00000522603.5
ENST00000541428.5
ENST00000522349.5
ENST00000522835.5
ENST00000518306.5
ASPH
aspartate beta-hydroxylase
chr17_+_46624036 0.67 ENST00000575068.5
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
chr5_+_173918216 0.67 ENST00000519467.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr5_-_11589019 0.67 ENST00000511377.5
CTNND2
catenin delta 2
chr6_-_136550407 0.67 ENST00000354570.8
MAP7
microtubule associated protein 7
chr7_+_23299306 0.67 ENST00000466681.2
MALSU1
mitochondrial assembly of ribosomal large subunit 1
chr12_-_7503841 0.66 ENST00000359156.8
CD163
CD163 molecule
chr18_-_66604076 0.66 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
CDH19
cadherin 19
chr5_-_88884525 0.66 ENST00000502983.5
MEF2C
myocyte enhancer factor 2C
chr5_+_98773651 0.65 ENST00000513185.3
RGMB
repulsive guidance molecule BMP co-receptor b
chr5_+_142770367 0.65 ENST00000645722.2
ENST00000274498.9
ARHGAP26
Rho GTPase activating protein 26
chr2_+_233691607 0.65 ENST00000373424.5
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr11_+_6921002 0.65 ENST00000317834.5
OR2D3
olfactory receptor family 2 subfamily D member 3
chr4_+_159267154 0.65 ENST00000510510.5
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr2_+_178320228 0.65 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr5_-_11588842 0.65 ENST00000503622.5
CTNND2
catenin delta 2
chrY_-_6874027 0.65 ENST00000215479.10
AMELY
amelogenin Y-linked
chr18_+_58196736 0.64 ENST00000675221.1
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr19_-_11346196 0.64 ENST00000586218.5
TMEM205
transmembrane protein 205
chr1_-_241999091 0.63 ENST00000357246.4
MAP1LC3C
microtubule associated protein 1 light chain 3 gamma
chr12_-_81598360 0.63 ENST00000333447.11
ENST00000407050.8
PPFIA2
PTPRF interacting protein alpha 2
chr10_+_70093626 0.62 ENST00000678195.1
MACROH2A2
macroH2A.2 histone
chr11_-_58731968 0.62 ENST00000278400.3
GLYAT
glycine-N-acyltransferase
chr4_+_94974984 0.62 ENST00000672698.1
BMPR1B
bone morphogenetic protein receptor type 1B
chr7_-_117872209 0.62 ENST00000454375.5
CTTNBP2
cortactin binding protein 2
chr12_+_55492378 0.62 ENST00000548615.1
OR6C68
olfactory receptor family 6 subfamily C member 68
chr8_+_66126896 0.62 ENST00000353317.9
TRIM55
tripartite motif containing 55
chr5_+_137867868 0.60 ENST00000515645.1
MYOT
myotilin
chr11_-_4288083 0.60 ENST00000638166.1
SSU72P4
SSU72 pseudogene 4
chr11_+_55262152 0.60 ENST00000417545.5
TRIM48
tripartite motif containing 48
chr10_-_45315608 0.60 ENST00000553795.6
OR13A1
olfactory receptor family 13 subfamily A member 1
chr15_-_26629083 0.59 ENST00000400188.7
GABRB3
gamma-aminobutyric acid type A receptor subunit beta3
chr11_-_58268260 0.59 ENST00000395079.2
OR10W1
olfactory receptor family 10 subfamily W member 1
chr12_-_16608073 0.59 ENST00000441439.6
LMO3
LIM domain only 3
chr3_-_9249623 0.58 ENST00000383836.8
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr6_+_3258914 0.58 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome assembly chaperone 4
chr4_+_94995919 0.58 ENST00000509540.6
BMPR1B
bone morphogenetic protein receptor type 1B
chr16_-_75701459 0.58 ENST00000633875.4
DUXB
double homeobox B
chr3_+_69936583 0.57 ENST00000314557.10
ENST00000394351.9
MITF
melanocyte inducing transcription factor
chrX_+_11293411 0.56 ENST00000348912.4
ENST00000380714.7
ENST00000380712.7
AMELX
amelogenin X-linked
chr2_+_75646775 0.56 ENST00000393909.7
ENST00000358788.10
ENST00000409374.5
MRPL19
mitochondrial ribosomal protein L19
chr4_+_75724569 0.56 ENST00000514213.7
ENST00000264904.8
USO1
USO1 vesicle transport factor
chr18_-_55322334 0.56 ENST00000630720.3
TCF4
transcription factor 4
chr6_-_27867581 0.55 ENST00000331442.5
H1-5
H1.5 linker histone, cluster member
chr12_-_81598332 0.55 ENST00000443686.7
PPFIA2
PTPRF interacting protein alpha 2
chr2_-_172102893 0.54 ENST00000234198.9
ENST00000466293.2
DLX2
distal-less homeobox 2
chr6_+_30914360 0.54 ENST00000421263.1
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr12_-_10807286 0.54 ENST00000240615.3
TAS2R8
taste 2 receptor member 8
chr11_-_58731936 0.54 ENST00000344743.8
GLYAT
glycine-N-acyltransferase
chr7_+_90709231 0.53 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr1_+_12857086 0.53 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr9_+_27524285 0.53 ENST00000276943.3
IFNK
interferon kappa
chr5_+_151020438 0.52 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr21_-_41926680 0.51 ENST00000329623.11
C2CD2
C2 calcium dependent domain containing 2
chr1_+_186296267 0.51 ENST00000533951.5
ENST00000367482.8
ENST00000635041.1
ENST00000367483.8
ENST00000367485.4
ENST00000445192.7
PRG4
proteoglycan 4
chr16_+_7332839 0.51 ENST00000355637.9
RBFOX1
RNA binding fox-1 homolog 1
chr4_+_159267737 0.50 ENST00000264431.8
RAPGEF2
Rap guanine nucleotide exchange factor 2
chr14_-_81427390 0.50 ENST00000555447.5
STON2
stonin 2
chr5_-_11588796 0.50 ENST00000513598.5
CTNND2
catenin delta 2
chr7_+_123601815 0.50 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr4_-_99435396 0.49 ENST00000209665.8
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_169250825 0.48 ENST00000676869.1
ENST00000676760.1
THBS2
thrombospondin 2
chr2_+_186694007 0.48 ENST00000304698.10
FAM171B
family with sequence similarity 171 member B
chr4_-_99435336 0.47 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr4_+_168654724 0.47 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr16_+_6483379 0.46 ENST00000552089.5
RBFOX1
RNA binding fox-1 homolog 1
chr4_-_46388713 0.46 ENST00000507069.5
GABRA2
gamma-aminobutyric acid type A receptor subunit alpha2
chr4_-_71784046 0.46 ENST00000513476.5
ENST00000273951.13
GC
GC vitamin D binding protein
chr8_-_10655137 0.46 ENST00000382483.4
RP1L1
RP1 like 1
chr8_-_101790934 0.45 ENST00000523645.5
ENST00000520346.1
ENST00000220931.11
ENST00000522448.5
ENST00000522951.5
ENST00000522252.5
ENST00000519098.5
NCALD
neurocalcin delta
chr1_-_157099798 0.45 ENST00000454449.3
ETV3L
ETS variant transcription factor 3 like
chr11_+_24496988 0.45 ENST00000336930.11
LUZP2
leucine zipper protein 2
chr9_+_74615582 0.45 ENST00000396204.2
RORB
RAR related orphan receptor B
chr4_-_89029881 0.44 ENST00000506913.1
FAM13A
family with sequence similarity 13 member A
chr7_-_93890744 0.44 ENST00000650573.1
ENST00000222543.11
ENST00000649913.1
ENST00000647793.1
TFPI2
tissue factor pathway inhibitor 2
chr9_-_92536645 0.44 ENST00000395534.2
ECM2
extracellular matrix protein 2
chr7_+_123601836 0.44 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr16_-_21864103 0.44 ENST00000541674.5
NPIPB4
nuclear pore complex interacting protein family member B4
chr5_+_141402764 0.43 ENST00000573521.2
ENST00000616887.1
PCDHGA9
protocadherin gamma subfamily A, 9
chr3_-_87276577 0.43 ENST00000344265.8
ENST00000350375.7
POU1F1
POU class 1 homeobox 1
chr7_+_138460238 0.42 ENST00000343526.9
TRIM24
tripartite motif containing 24
chr1_+_248095184 0.42 ENST00000358120.3
ENST00000641893.1
OR2L13
olfactory receptor family 2 subfamily L member 13
chr4_+_87832917 0.42 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr1_+_12916610 0.42 ENST00000616979.4
PRAMEF7
PRAME family member 7
chr12_-_10826358 0.42 ENST00000240619.2
TAS2R10
taste 2 receptor member 10
chr3_+_35642159 0.41 ENST00000187397.8
ARPP21
cAMP regulated phosphoprotein 21
chr11_-_82997394 0.41 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chr3_-_33718207 0.41 ENST00000359576.9
ENST00000682230.1
ENST00000399362.8
CLASP2
cytoplasmic linker associated protein 2
chr11_+_113908983 0.41 ENST00000537778.5
HTR3B
5-hydroxytryptamine receptor 3B
chr2_-_182427014 0.40 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr6_+_30163541 0.39 ENST00000376694.9
TRIM15
tripartite motif containing 15
chr7_+_123601859 0.39 ENST00000437535.5
ASB15
ankyrin repeat and SOCS box containing 15
chr4_+_87650277 0.39 ENST00000339673.11
ENST00000282479.8
DMP1
dentin matrix acidic phosphoprotein 1
chr12_-_75390890 0.39 ENST00000552497.5
ENST00000551829.5
ENST00000436898.5
CAPS2
calcyphosine 2
chr10_+_24466487 0.38 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217

Network of associatons between targets according to the STRING database.

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
1.2 3.5 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.9 3.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.9 2.6 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.7 2.6 GO:0006550 isoleucine catabolic process(GO:0006550) acetyl-CoA catabolic process(GO:0046356) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.5 6.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.5 1.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.4 1.8 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.4 9.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 1.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 2.3 GO:0021764 amygdala development(GO:0021764)
0.3 1.0 GO:0060003 copper ion export(GO:0060003)
0.3 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 2.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 1.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 2.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.2 0.7 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.2 0.9 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.2 0.9 GO:0002188 translation reinitiation(GO:0002188)
0.2 1.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 1.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 0.7 GO:0044407 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.2 1.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.7 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.2 0.7 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 1.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 2.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 3.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 1.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 1.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0021622 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.8 GO:0006549 isoleucine metabolic process(GO:0006549)
0.1 1.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 2.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.7 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.1 0.9 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.2 GO:0034758 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.4 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.5 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.6 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.5 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.7 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.2 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 2.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 2.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 4.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 4.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 6.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 2.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 1.2 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 3.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.9 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 2.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 7.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 1.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 8.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.3 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 1.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.4 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.0 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.5 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.2 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.8 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.4 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.3 1.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 3.9 GO:0005577 fibrinogen complex(GO:0005577)
0.3 0.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.4 GO:1990032 parallel fiber(GO:1990032)
0.2 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 1.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 6.1 GO:0005922 connexon complex(GO:0005922)
0.1 2.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.3 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.1 GO:0070852 cell body fiber(GO:0070852)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 2.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.1 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.0 8.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 6.8 GO:0016605 PML body(GO:0016605)
0.0 3.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 6.0 GO:0030018 Z disc(GO:0030018)
0.0 2.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 4.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.0 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 10.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 6.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.7 2.6 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.5 1.8 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.4 1.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 6.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.2 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 9.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.0 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.2 2.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.0 GO:0004064 arylesterase activity(GO:0004064)
0.2 0.6 GO:0046848 hydroxyapatite binding(GO:0046848)
0.2 0.9 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.2 1.3 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.8 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.2 1.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 2.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.8 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 2.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 2.6 GO:0005522 profilin binding(GO:0005522)
0.1 1.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.5 GO:0070052 collagen V binding(GO:0070052)
0.1 3.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0008431 vitamin E binding(GO:0008431)
0.1 1.1 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 2.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 1.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 3.5 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 1.9 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 2.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 2.1 GO:0005549 odorant binding(GO:0005549)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.5 GO:0030332 cyclin binding(GO:0030332)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0008430 selenium binding(GO:0008430)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 5.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 2.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.6 PID BMP PATHWAY BMP receptor signaling
0.0 10.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID INSULIN PATHWAY Insulin Pathway
0.0 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 3.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 4.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 6.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 3.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 2.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 2.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 4.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D