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Illumina Body Map 2 (GSE30611)

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Results for PTF1A

Z-value: 0.76

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
ENSG00000168267.7 pancreas associated transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PTF1Ahg38_v1_chr10_+_23192306_23192320-0.115.6e-01Click!

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_57251169 1.61 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr8_+_11494367 1.58 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr3_+_35679690 1.56 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21
chr3_+_35679614 1.50 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
cAMP regulated phosphoprotein 21
chr1_-_9069608 1.44 ENST00000377424.9
solute carrier family 2 member 5
chr2_-_89213917 1.28 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr17_+_69502397 1.28 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr14_-_106875069 1.18 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr4_+_40196907 1.17 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr3_-_155293665 1.17 ENST00000489090.2
small transmembrane regulator of ion transport 1
chr6_-_159045010 1.15 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr14_-_106025628 1.10 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr3_+_35639515 1.08 ENST00000684406.1
cAMP regulated phosphoprotein 21
chr2_+_88897230 1.06 ENST00000390244.2
immunoglobulin kappa variable 5-2
chr6_-_159044980 1.06 ENST00000367066.8
T cell activation RhoGTPase activating protein
chr6_-_159045104 1.01 ENST00000326965.7
T cell activation RhoGTPase activating protein
chr3_+_35639589 0.97 ENST00000428373.5
cAMP regulated phosphoprotein 21
chr1_-_9069572 0.97 ENST00000377414.7
solute carrier family 2 member 5
chr14_-_106470788 0.96 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr11_-_1598294 0.92 ENST00000412090.2
keratin associated protein 5-2
chr11_+_73646558 0.92 ENST00000536527.5
ENST00000354190.10
pleckstrin homology domain containing B1
chr11_-_45665578 0.90 ENST00000308064.7
carbohydrate sulfotransferase 1
chr6_-_24877262 0.85 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr1_-_9069797 0.84 ENST00000473209.1
solute carrier family 2 member 5
chr1_-_230978796 0.84 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
tetratricopeptide repeat domain 13
chr2_-_70768175 0.80 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
adducin 2
chr17_+_69502154 0.79 ENST00000589295.5
mitogen-activated protein kinase kinase 6
chr22_-_50085378 0.79 ENST00000442311.1
modulator of VRAC current 1
chr4_+_40197023 0.78 ENST00000381799.10
ras homolog family member H
chr17_+_69502255 0.76 ENST00000588110.5
mitogen-activated protein kinase kinase 6
chr22_-_50085331 0.76 ENST00000395876.6
modulator of VRAC current 1
chr17_-_75896911 0.73 ENST00000540128.1
ENST00000269383.8
tripartite motif containing 65
chr19_+_29665444 0.69 ENST00000592810.1
ENST00000436066.4
pleckstrin homology and FYVE domain containing 1
chr3_+_35679638 0.67 ENST00000432450.5
cAMP regulated phosphoprotein 21
chr8_-_22232020 0.63 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr22_+_22668286 0.58 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr3_+_167735238 0.58 ENST00000472941.5
serpin family I member 1
chr12_-_75209814 0.57 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chr12_-_75209701 0.56 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr1_+_26529745 0.55 ENST00000374168.7
ENST00000374166.8
ribosomal protein S6 kinase A1
chr15_+_90903731 0.54 ENST00000559965.5
mannosidase alpha class 2A member 2
chr1_-_113905020 0.54 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
adaptor related protein complex 4 subunit beta 1
chr19_+_29665493 0.53 ENST00000588833.1
pleckstrin homology and FYVE domain containing 1
chr3_+_167735704 0.50 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr3_+_35638847 0.49 ENST00000450234.5
cAMP regulated phosphoprotein 21
chrX_-_21658324 0.48 ENST00000379499.3
kelch like family member 34
chr13_-_31162341 0.48 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chr6_-_62286161 0.48 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr10_+_48684859 0.47 ENST00000360890.6
ENST00000325239.11
WDFY family member 4
chr2_+_85695368 0.47 ENST00000526018.1
granulysin
chr3_-_112133218 0.47 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr15_-_89221558 0.47 ENST00000268125.10
retinaldehyde binding protein 1
chr20_-_63216102 0.46 ENST00000370339.8
ENST00000370334.4
YTH N6-methyladenosine RNA binding protein 1
chr7_+_142380781 0.45 ENST00000390360.3
T cell receptor beta variable 6-4
chr17_-_3557798 0.44 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
transient receptor potential cation channel subfamily V member 3
chr6_-_127459364 0.44 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr2_+_172735838 0.42 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr3_-_69200711 0.42 ENST00000478263.5
ENST00000462512.1
FERM domain containing 4B
chr2_-_71227055 0.41 ENST00000244221.9
poly(A) binding protein interacting protein 2B
chr19_-_7700074 0.41 ENST00000593418.1
Fc fragment of IgE receptor II
chr17_+_42844573 0.40 ENST00000253799.8
ENST00000452774.2
amine oxidase copper containing 2
chr11_+_64340191 0.40 ENST00000356786.10
coiled-coil domain containing 88B
chr15_+_80933358 0.39 ENST00000560027.1
cell migration inducing hyaluronidase 1
chr1_+_113905156 0.39 ENST00000650596.1
DNA cross-link repair 1B
chr10_+_122980448 0.38 ENST00000405485.2
phosphoseryl-tRNA kinase
chr20_+_46008900 0.36 ENST00000372330.3
matrix metallopeptidase 9
chr1_-_45491150 0.36 ENST00000372086.4
testis associated actin remodelling kinase 2
chr16_+_46884675 0.36 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chr3_+_48989876 0.36 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr4_-_82798735 0.35 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr8_-_109648825 0.34 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr13_-_31161890 0.34 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr10_-_122845850 0.33 ENST00000392790.6
CUB and zona pellucida like domains 1
chr2_+_218880844 0.33 ENST00000258411.8
Wnt family member 10A
chr2_+_218125276 0.32 ENST00000453237.5
C-X-C motif chemokine receptor 2
chr3_-_12841527 0.32 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
ribosomal protein L32
chr19_-_10380454 0.32 ENST00000530829.1
ENST00000529370.5
tyrosine kinase 2
chr8_-_109648746 0.31 ENST00000528045.5
syntabulin
chr2_-_159904668 0.30 ENST00000504764.5
ENST00000505052.1
ENST00000263636.5
LY75-CD302 readthrough
lymphocyte antigen 75
chr10_+_122980392 0.29 ENST00000406217.8
phosphoseryl-tRNA kinase
chr11_-_84166998 0.28 ENST00000398299.1
discs large MAGUK scaffold protein 2
chr16_-_1954682 0.28 ENST00000268661.8
ribosomal protein L3 like
chr3_+_48990338 0.28 ENST00000475629.5
ENST00000444213.5
prolyl 4-hydroxylase, transmembrane
chr8_-_38269157 0.28 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
phospholipid phosphatase 5
chr10_+_75111595 0.27 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
sterile alpha motif domain containing 8
chr1_-_113904789 0.27 ENST00000369569.6
ENST00000369567.5
adaptor related protein complex 4 subunit beta 1
chr11_+_57181945 0.27 ENST00000497933.3
leucine rich repeat containing 55
chr12_+_1820558 0.26 ENST00000299194.6
leucine rich repeats and transmembrane domains 2
chr14_-_23572975 0.26 ENST00000544177.1
junctophilin 4
chr19_+_17952266 0.26 ENST00000609922.2
potassium calcium-activated channel subfamily N member 1
chr3_+_101827982 0.25 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr3_-_52834901 0.25 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr12_+_50057548 0.25 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chr2_+_201258103 0.25 ENST00000413726.5
caspase 8
chr17_-_38343810 0.25 ENST00000621958.1
ENST00000616987.5
G protein-coupled receptor 179
chr16_+_89630263 0.25 ENST00000261615.5
dipeptidase 1
chr7_-_5513738 0.24 ENST00000453700.7
ENST00000382368.8
F-box and leucine rich repeat protein 18
chr9_-_111036207 0.24 ENST00000541779.5
lysophosphatidic acid receptor 1
chr19_-_9219589 0.24 ENST00000641244.1
ENST00000641669.1
olfactory receptor family 7 subfamily D member 4
chr20_+_18145083 0.24 ENST00000489634.2
lysine acetyltransferase 14
chr8_-_134712962 0.24 ENST00000523399.5
ENST00000377838.8
zinc finger and AT-hook domain containing
chr12_+_1820255 0.22 ENST00000543818.5
leucine rich repeats and transmembrane domains 2
chr1_+_113905290 0.22 ENST00000650450.2
DNA cross-link repair 1B
chr3_+_48990219 0.22 ENST00000383729.9
prolyl 4-hydroxylase, transmembrane
chr9_+_33795551 0.21 ENST00000379405.4
serine protease 3
chr5_+_132813283 0.21 ENST00000378693.4
sosondowah ankyrin repeat domain family member A
chr8_+_49911396 0.21 ENST00000642720.2
syntrophin gamma 1
chr2_-_106160376 0.20 ENST00000479621.5
UDP-glucuronate decarboxylase 1
chr7_-_22356914 0.20 ENST00000344041.10
Rap guanine nucleotide exchange factor 5
chr7_-_22357112 0.20 ENST00000405243.1
ENST00000665637.1
Rap guanine nucleotide exchange factor 5
chr8_+_32548303 0.20 ENST00000650967.1
neuregulin 1
chr8_-_38269116 0.20 ENST00000529359.5
phospholipid phosphatase 5
chr5_+_126465144 0.20 ENST00000511134.1
GRAM domain containing 2B
chr12_+_120446418 0.19 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C
chr14_+_69879408 0.19 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr19_+_17215716 0.19 ENST00000593597.1
unconventional SNARE in the ER 1
chr16_-_75535247 0.18 ENST00000565039.1
carbohydrate sulfotransferase 5
chr4_-_174829212 0.18 ENST00000340217.5
ENST00000274093.8
glycine receptor alpha 3
chr7_+_143052341 0.18 ENST00000418316.2
olfactory receptor family 6 subfamily V member 1
chrX_+_15790446 0.18 ENST00000380308.7
ENST00000307771.8
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
chr6_-_2962123 0.18 ENST00000644875.1
serpin family B member 6
chr2_+_201257980 0.17 ENST00000447616.5
ENST00000358485.8
ENST00000392266.7
caspase 8
chr3_-_52835011 0.17 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr2_-_27211742 0.16 ENST00000408041.5
ENST00000401463.5
solute carrier family 5 member 6
chr19_+_9178979 0.16 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr12_-_57846686 0.15 ENST00000548823.1
ENST00000398073.7
CTD small phosphatase 2
chr12_-_121534651 0.15 ENST00000545022.5
lysine demethylase 2B
chr19_+_15082211 0.15 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr2_-_236503688 0.15 ENST00000418802.2
ENST00000431676.6
IQ motif containing with AAA domain 1
chr11_+_96389985 0.15 ENST00000332349.5
JRK like
chr15_-_72231583 0.15 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
pyruvate kinase M1/2
chr12_+_109154661 0.15 ENST00000544726.2
acetyl-CoA carboxylase beta
chr20_+_43916142 0.14 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr2_-_106160106 0.13 ENST00000479774.5
UDP-glucuronate decarboxylase 1
chr9_+_104504263 0.13 ENST00000334726.3
olfactory receptor family 13 subfamily F member 1
chr7_+_142760398 0.13 ENST00000632998.1
serine protease 2
chr8_+_32548210 0.13 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr5_-_163460067 0.13 ENST00000302764.9
NudC domain containing 2
chr11_-_102705737 0.13 ENST00000260229.5
matrix metallopeptidase 27
chr19_+_54573781 0.13 ENST00000391738.8
ENST00000251376.7
ENST00000391737.3
ENST00000629481.1
leukocyte immunoglobulin like receptor A2
chrX_+_155881306 0.12 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr11_+_8683201 0.12 ENST00000526562.5
ENST00000525981.1
ribosomal protein L27a
chr15_-_72231113 0.12 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
pyruvate kinase M1/2
chr3_-_56977354 0.12 ENST00000473779.5
Rho guanine nucleotide exchange factor 3
chr12_-_120446372 0.11 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr11_-_61967127 0.11 ENST00000532601.1
ferritin heavy chain 1
chr11_+_6863057 0.11 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr1_-_20119527 0.11 ENST00000375105.8
ENST00000617227.1
phospholipase A2 group IID
chr7_-_101200912 0.11 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr11_+_64291285 0.11 ENST00000422670.7
ENST00000538767.1
potassium two pore domain channel subfamily K member 4
chr19_-_39840671 0.11 ENST00000597224.5
fibrillarin
chr2_+_43838963 0.11 ENST00000272286.4
ATP binding cassette subfamily G member 8
chr17_+_51165435 0.11 ENST00000514264.6
NME/NM23 nucleoside diphosphate kinase 2
chr16_-_85112390 0.10 ENST00000629253.1
ENST00000539556.6
CBY1 interacting BAR domain containing 2
chr1_+_12125892 0.10 ENST00000413146.6
TNF receptor superfamily member 8
chr3_+_40477107 0.10 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr12_+_2803197 0.09 ENST00000544366.1
FKBP prolyl isomerase 4
chr13_+_112979306 0.09 ENST00000421756.5
MCF.2 cell line derived transforming sequence like
chr12_+_56996151 0.09 ENST00000556850.1
G protein-coupled receptor 182
chr13_-_79405784 0.08 ENST00000267229.11
RNA binding motif protein 26
chr10_-_27243019 0.08 ENST00000679293.1
acyl-CoA binding domain containing 5
chr6_-_159788439 0.08 ENST00000539948.5
t-complex 1
chr2_-_27211888 0.08 ENST00000426119.5
ENST00000412471.5
solute carrier family 5 member 6
chr1_-_204685700 0.08 ENST00000367177.4
leucine rich repeat neuronal 2
chr11_-_96389857 0.07 ENST00000680532.1
ENST00000681014.1
ENST00000679708.1
ENST00000645439.1
ENST00000645366.1
ENST00000680728.1
ENST00000680859.1
ENST00000679788.1
ENST00000681164.1
ENST00000646818.2
ENST00000680171.1
ENST00000679696.1
ENST00000681200.1
ENST00000679960.1
ENST00000647080.1
ENST00000646050.1
ENST00000681451.1
ENST00000644686.1
ENST00000680052.1
ENST00000679616.1
ENST00000530203.2
coiled-coil domain containing 82
chr10_-_73096974 0.07 ENST00000440381.5
ENST00000263556.3
prolyl 4-hydroxylase subunit alpha 1
chr18_-_26546990 0.07 ENST00000578973.1
potassium channel tetramerization domain containing 1
chr12_+_53295506 0.06 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr7_+_142111739 0.06 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr17_+_12789697 0.06 ENST00000262444.13
Rho GTPase activating protein 44
chr3_-_50359480 0.06 ENST00000266025.4
transmembrane protein 115
chr3_+_130929998 0.06 ENST00000508297.2
ATPase secretory pathway Ca2+ transporting 1
chr14_-_58427114 0.05 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr8_-_124565699 0.05 ENST00000519168.5
MTSS I-BAR domain containing 1
chr11_-_1585283 0.05 ENST00000382171.2
keratin associated protein 5-1
chr20_-_3663399 0.05 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr15_+_68631988 0.05 ENST00000543950.3
coronin 2B
chr2_+_3389681 0.05 ENST00000457845.4
ENST00000441983.5
trafficking protein particle complex 12
chr14_-_58427134 0.04 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr15_+_51341648 0.04 ENST00000335449.11
ENST00000560215.5
gliomedin
chr2_+_96760857 0.04 ENST00000377075.3
cyclin and CBS domain divalent metal cation transport mediator 4
chr16_+_71358713 0.04 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr11_-_96389936 0.04 ENST00000680763.1
ENST00000679856.1
ENST00000643839.1
ENST00000645500.1
ENST00000530106.2
coiled-coil domain containing 82
chr5_-_75717368 0.04 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5 centriolar protein
chr6_-_24489565 0.04 ENST00000230036.2
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_61829281 0.04 ENST00000448607.1
ENST00000421879.5
fatty acid desaturase 1
chr17_-_7211808 0.04 ENST00000648658.1
discs large MAGUK scaffold protein 4
chr8_+_32548267 0.04 ENST00000356819.7
neuregulin 1
chr2_+_227728335 0.03 ENST00000641700.1
small cysteine and glycine repeat containing 7
chr19_-_1169138 0.03 ENST00000587655.2
strawberry notch homolog 2
chr20_+_56248732 0.03 ENST00000243911.2
melanocortin 3 receptor
chr9_-_101383558 0.03 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr11_-_89876017 0.03 ENST00000329862.6
tripartite motif containing 64B
chr12_+_30926428 0.03 ENST00000545802.1
tetraspanin 11
chr1_+_39738866 0.03 ENST00000324379.10
ENST00000356511.6
ENST00000497370.5
ENST00000470213.5
ENST00000372835.9
ENST00000372830.5
peptidylprolyl isomerase E
chr21_+_33205279 0.03 ENST00000683941.1
interferon alpha and beta receptor subunit 2
chr6_+_167271163 0.03 ENST00000503433.5
unc-93 homolog A
chr10_-_73096850 0.03 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr11_+_193078 0.02 ENST00000342878.3
secretoglobin family 1C member 1
chr12_+_51238724 0.02 ENST00000449723.7
ENST00000549555.5
ENST00000439799.6
ENST00000412716.8
ENST00000425012.6
DAZ associated protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 3.3 GO:0097319 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3 1.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.5 GO:0002818 intracellular defense response(GO:0002818)
0.1 0.8 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.7 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.8 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.6 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.4 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 0.4 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 1.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.4 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 1.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.1 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.0 1.6 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0051836 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 2.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 6.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 2.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.0 GO:0042309 homoiothermy(GO:0042309)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.9 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.5 GO:0044194 cytolytic granule(GO:0044194)
0.0 2.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 2.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.4 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 6.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.0 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling