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Illumina Body Map 2 (GSE30611)

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Results for PTF1A

Z-value: 0.76

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.7 pancreas associated transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PTF1Ahg38_v1_chr10_+_23192306_23192320-0.115.6e-01Click!

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_57251169 1.61 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
STAC3
SH3 and cysteine rich domain 3
chr8_+_11494367 1.58 ENST00000259089.9
ENST00000529894.1
BLK
BLK proto-oncogene, Src family tyrosine kinase
chr3_+_35679690 1.56 ENST00000413378.5
ENST00000417925.5
ARPP21
cAMP regulated phosphoprotein 21
chr3_+_35679614 1.50 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
ARPP21
cAMP regulated phosphoprotein 21
chr1_-_9069608 1.44 ENST00000377424.9
SLC2A5
solute carrier family 2 member 5
chr2_-_89213917 1.28 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr17_+_69502397 1.28 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr14_-_106875069 1.18 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr4_+_40196907 1.17 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
RHOH
ras homolog family member H
chr3_-_155293665 1.17 ENST00000489090.2
STRIT1
small transmembrane regulator of ion transport 1
chr6_-_159045010 1.15 ENST00000338313.5
TAGAP
T cell activation RhoGTPase activating protein
chr14_-_106025628 1.10 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr3_+_35639515 1.08 ENST00000684406.1
ARPP21
cAMP regulated phosphoprotein 21
chr2_+_88897230 1.06 ENST00000390244.2
IGKV5-2
immunoglobulin kappa variable 5-2
chr6_-_159044980 1.06 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr6_-_159045104 1.01 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr3_+_35639589 0.97 ENST00000428373.5
ARPP21
cAMP regulated phosphoprotein 21
chr1_-_9069572 0.97 ENST00000377414.7
SLC2A5
solute carrier family 2 member 5
chr14_-_106470788 0.96 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr11_-_1598294 0.92 ENST00000412090.2
KRTAP5-2
keratin associated protein 5-2
chr11_+_73646558 0.92 ENST00000536527.5
ENST00000354190.10
PLEKHB1
pleckstrin homology domain containing B1
chr11_-_45665578 0.90 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr6_-_24877262 0.85 ENST00000378023.8
ENST00000540914.5
RIPOR2
RHO family interacting cell polarization regulator 2
chr1_-_9069797 0.84 ENST00000473209.1
SLC2A5
solute carrier family 2 member 5
chr1_-_230978796 0.84 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
TTC13
tetratricopeptide repeat domain 13
chr2_-_70768175 0.80 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
ADD2
adducin 2
chr17_+_69502154 0.79 ENST00000589295.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr22_-_50085378 0.79 ENST00000442311.1
MLC1
modulator of VRAC current 1
chr4_+_40197023 0.78 ENST00000381799.10
RHOH
ras homolog family member H
chr17_+_69502255 0.76 ENST00000588110.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr22_-_50085331 0.76 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr17_-_75896911 0.73 ENST00000540128.1
ENST00000269383.8
TRIM65
tripartite motif containing 65
chr19_+_29665444 0.69 ENST00000592810.1
ENST00000436066.4
PLEKHF1
pleckstrin homology and FYVE domain containing 1
chr3_+_35679638 0.67 ENST00000432450.5
ARPP21
cAMP regulated phosphoprotein 21
chr8_-_22232020 0.63 ENST00000454243.7
ENST00000321613.7
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr22_+_22668286 0.58 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr3_+_167735238 0.58 ENST00000472941.5
SERPINI1
serpin family I member 1
chr12_-_75209814 0.57 ENST00000549446.6
KCNC2
potassium voltage-gated channel subfamily C member 2
chr12_-_75209701 0.56 ENST00000350228.6
ENST00000298972.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr1_+_26529745 0.55 ENST00000374168.7
ENST00000374166.8
RPS6KA1
ribosomal protein S6 kinase A1
chr15_+_90903731 0.54 ENST00000559965.5
MAN2A2
mannosidase alpha class 2A member 2
chr1_-_113905020 0.54 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
AP4B1
adaptor related protein complex 4 subunit beta 1
chr19_+_29665493 0.53 ENST00000588833.1
PLEKHF1
pleckstrin homology and FYVE domain containing 1
chr3_+_167735704 0.50 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
SERPINI1
serpin family I member 1
chr3_+_35638847 0.49 ENST00000450234.5
ARPP21
cAMP regulated phosphoprotein 21
chrX_-_21658324 0.48 ENST00000379499.3
KLHL34
kelch like family member 34
chr13_-_31162341 0.48 ENST00000445273.6
ENST00000630972.2
HSPH1
heat shock protein family H (Hsp110) member 1
chr6_-_62286161 0.48 ENST00000281156.5
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2
chr10_+_48684859 0.47 ENST00000360890.6
ENST00000325239.11
WDFY4
WDFY family member 4
chr2_+_85695368 0.47 ENST00000526018.1
GNLY
granulysin
chr3_-_112133218 0.47 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
GCSAM
germinal center associated signaling and motility
chr15_-_89221558 0.47 ENST00000268125.10
RLBP1
retinaldehyde binding protein 1
chr20_-_63216102 0.46 ENST00000370339.8
ENST00000370334.4
YTHDF1
YTH N6-methyladenosine RNA binding protein 1
chr7_+_142380781 0.45 ENST00000390360.3
TRBV6-4
T cell receptor beta variable 6-4
chr17_-_3557798 0.44 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
TRPV3
transient receptor potential cation channel subfamily V member 3
chr6_-_127459364 0.44 ENST00000487331.2
ENST00000483725.8
KIAA0408
KIAA0408
chr2_+_172735838 0.42 ENST00000397081.8
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr3_-_69200711 0.42 ENST00000478263.5
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr2_-_71227055 0.41 ENST00000244221.9
PAIP2B
poly(A) binding protein interacting protein 2B
chr19_-_7700074 0.41 ENST00000593418.1
FCER2
Fc fragment of IgE receptor II
chr17_+_42844573 0.40 ENST00000253799.8
ENST00000452774.2
AOC2
amine oxidase copper containing 2
chr11_+_64340191 0.40 ENST00000356786.10
CCDC88B
coiled-coil domain containing 88B
chr15_+_80933358 0.39 ENST00000560027.1
CEMIP
cell migration inducing hyaluronidase 1
chr1_+_113905156 0.39 ENST00000650596.1
DCLRE1B
DNA cross-link repair 1B
chr10_+_122980448 0.38 ENST00000405485.2
PSTK
phosphoseryl-tRNA kinase
chr20_+_46008900 0.36 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr1_-_45491150 0.36 ENST00000372086.4
TESK2
testis associated actin remodelling kinase 2
chr16_+_46884675 0.36 ENST00000562132.5
ENST00000440783.2
GPT2
glutamic--pyruvic transaminase 2
chr3_+_48989876 0.36 ENST00000343546.8
P4HTM
prolyl 4-hydroxylase, transmembrane
chr4_-_82798735 0.35 ENST00000273908.4
ENST00000319540.9
SCD5
stearoyl-CoA desaturase 5
chr8_-_109648825 0.34 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
SYBU
syntabulin
chr13_-_31161890 0.34 ENST00000320027.10
HSPH1
heat shock protein family H (Hsp110) member 1
chr10_-_122845850 0.33 ENST00000392790.6
CUZD1
CUB and zona pellucida like domains 1
chr2_+_218880844 0.33 ENST00000258411.8
WNT10A
Wnt family member 10A
chr2_+_218125276 0.32 ENST00000453237.5
CXCR2
C-X-C motif chemokine receptor 2
chr3_-_12841527 0.32 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
RPL32
ribosomal protein L32
chr19_-_10380454 0.32 ENST00000530829.1
ENST00000529370.5
TYK2
tyrosine kinase 2
chr8_-_109648746 0.31 ENST00000528045.5
SYBU
syntabulin
chr2_-_159904668 0.30 ENST00000504764.5
ENST00000505052.1
ENST00000263636.5
LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chr10_+_122980392 0.29 ENST00000406217.8
PSTK
phosphoseryl-tRNA kinase
chr11_-_84166998 0.28 ENST00000398299.1
DLG2
discs large MAGUK scaffold protein 2
chr16_-_1954682 0.28 ENST00000268661.8
RPL3L
ribosomal protein L3 like
chr3_+_48990338 0.28 ENST00000475629.5
ENST00000444213.5
P4HTM
prolyl 4-hydroxylase, transmembrane
chr8_-_38269157 0.28 ENST00000531823.5
ENST00000534339.5
ENST00000524616.5
ENST00000422581.6
ENST00000424479.7
ENST00000419686.2
PLPP5
phospholipid phosphatase 5
chr10_+_75111595 0.27 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr1_-_113904789 0.27 ENST00000369569.6
ENST00000369567.5
AP4B1
adaptor related protein complex 4 subunit beta 1
chr11_+_57181945 0.27 ENST00000497933.3
LRRC55
leucine rich repeat containing 55
chr12_+_1820558 0.26 ENST00000299194.6
LRTM2
leucine rich repeats and transmembrane domains 2
chr14_-_23572975 0.26 ENST00000544177.1
JPH4
junctophilin 4
chr19_+_17952266 0.26 ENST00000609922.2
KCNN1
potassium calcium-activated channel subfamily N member 1
chr3_+_101827982 0.25 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr3_-_52834901 0.25 ENST00000486659.5
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr12_+_50057548 0.25 ENST00000228468.8
ENST00000447966.7
ASIC1
acid sensing ion channel subunit 1
chr2_+_201258103 0.25 ENST00000413726.5
CASP8
caspase 8
chr17_-_38343810 0.25 ENST00000621958.1
ENST00000616987.5
GPR179
G protein-coupled receptor 179
chr16_+_89630263 0.25 ENST00000261615.5
DPEP1
dipeptidase 1
chr7_-_5513738 0.24 ENST00000453700.7
ENST00000382368.8
FBXL18
F-box and leucine rich repeat protein 18
chr9_-_111036207 0.24 ENST00000541779.5
LPAR1
lysophosphatidic acid receptor 1
chr19_-_9219589 0.24 ENST00000641244.1
ENST00000641669.1
OR7D4
olfactory receptor family 7 subfamily D member 4
chr20_+_18145083 0.24 ENST00000489634.2
KAT14
lysine acetyltransferase 14
chr8_-_134712962 0.24 ENST00000523399.5
ENST00000377838.8
ZFAT
zinc finger and AT-hook domain containing
chr12_+_1820255 0.22 ENST00000543818.5
LRTM2
leucine rich repeats and transmembrane domains 2
chr1_+_113905290 0.22 ENST00000650450.2
DCLRE1B
DNA cross-link repair 1B
chr3_+_48990219 0.22 ENST00000383729.9
P4HTM
prolyl 4-hydroxylase, transmembrane
chr9_+_33795551 0.21 ENST00000379405.4
PRSS3
serine protease 3
chr5_+_132813283 0.21 ENST00000378693.4
SOWAHA
sosondowah ankyrin repeat domain family member A
chr8_+_49911396 0.21 ENST00000642720.2
SNTG1
syntrophin gamma 1
chr2_-_106160376 0.20 ENST00000479621.5
UXS1
UDP-glucuronate decarboxylase 1
chr7_-_22356914 0.20 ENST00000344041.10
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr7_-_22357112 0.20 ENST00000405243.1
ENST00000665637.1
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr8_+_32548303 0.20 ENST00000650967.1
NRG1
neuregulin 1
chr8_-_38269116 0.20 ENST00000529359.5
PLPP5
phospholipid phosphatase 5
chr5_+_126465144 0.20 ENST00000511134.1
GRAMD2B
GRAM domain containing 2B
chr12_+_120446418 0.19 ENST00000551765.6
ENST00000229384.5
GATC
glutamyl-tRNA amidotransferase subunit C
chr14_+_69879408 0.19 ENST00000361956.8
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr19_+_17215716 0.19 ENST00000593597.1
USE1
unconventional SNARE in the ER 1
chr16_-_75535247 0.18 ENST00000565039.1
CHST5
carbohydrate sulfotransferase 5
chr4_-_174829212 0.18 ENST00000340217.5
ENST00000274093.8
GLRA3
glycine receptor alpha 3
chr7_+_143052341 0.18 ENST00000418316.2
OR6V1
olfactory receptor family 6 subfamily V member 1
chrX_+_15790446 0.18 ENST00000380308.7
ENST00000307771.8
ZRSR2
zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
chr6_-_2962123 0.18 ENST00000644875.1
SERPINB6
serpin family B member 6
chr2_+_201257980 0.17 ENST00000447616.5
ENST00000358485.8
ENST00000392266.7
CASP8
caspase 8
chr3_-_52835011 0.17 ENST00000446157.3
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr2_-_27211742 0.16 ENST00000408041.5
ENST00000401463.5
SLC5A6
solute carrier family 5 member 6
chr19_+_9178979 0.16 ENST00000642043.1
ENST00000641288.2
OR7D2
olfactory receptor family 7 subfamily D member 2
chr12_-_57846686 0.15 ENST00000548823.1
ENST00000398073.7
CTDSP2
CTD small phosphatase 2
chr12_-_121534651 0.15 ENST00000545022.5
KDM2B
lysine demethylase 2B
chr19_+_15082211 0.15 ENST00000641398.1
OR1I1
olfactory receptor family 1 subfamily I member 1
chr2_-_236503688 0.15 ENST00000418802.2
ENST00000431676.6
IQCA1
IQ motif containing with AAA domain 1
chr11_+_96389985 0.15 ENST00000332349.5
JRKL
JRK like
chr15_-_72231583 0.15 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
PKM
pyruvate kinase M1/2
chr12_+_109154661 0.15 ENST00000544726.2
ACACB
acetyl-CoA carboxylase beta
chr20_+_43916142 0.14 ENST00000423191.6
ENST00000372999.5
TOX2
TOX high mobility group box family member 2
chr2_-_106160106 0.13 ENST00000479774.5
UXS1
UDP-glucuronate decarboxylase 1
chr9_+_104504263 0.13 ENST00000334726.3
OR13F1
olfactory receptor family 13 subfamily F member 1
chr7_+_142760398 0.13 ENST00000632998.1
PRSS2
serine protease 2
chr8_+_32548210 0.13 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr5_-_163460067 0.13 ENST00000302764.9
NUDCD2
NudC domain containing 2
chr11_-_102705737 0.13 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr19_+_54573781 0.13 ENST00000391738.8
ENST00000251376.7
ENST00000391737.3
ENST00000629481.1
LILRA2
leukocyte immunoglobulin like receptor A2
chrX_+_155881306 0.12 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
VAMP7
vesicle associated membrane protein 7
chr11_+_8683201 0.12 ENST00000526562.5
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr15_-_72231113 0.12 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
PKM
pyruvate kinase M1/2
chr3_-_56977354 0.12 ENST00000473779.5
ARHGEF3
Rho guanine nucleotide exchange factor 3
chr12_-_120446372 0.11 ENST00000546954.2
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr11_-_61967127 0.11 ENST00000532601.1
FTH1
ferritin heavy chain 1
chr11_+_6863057 0.11 ENST00000641461.1
OR10A2
olfactory receptor family 10 subfamily A member 2
chr1_-_20119527 0.11 ENST00000375105.8
ENST00000617227.1
PLA2G2D
phospholipase A2 group IID
chr7_-_101200912 0.11 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
MOGAT3
monoacylglycerol O-acyltransferase 3
chr11_+_64291285 0.11 ENST00000422670.7
ENST00000538767.1
KCNK4
potassium two pore domain channel subfamily K member 4
chr19_-_39840671 0.11 ENST00000597224.5
FBL
fibrillarin
chr2_+_43838963 0.11 ENST00000272286.4
ABCG8
ATP binding cassette subfamily G member 8
chr17_+_51165435 0.11 ENST00000514264.6
NME2
NME/NM23 nucleoside diphosphate kinase 2
chr16_-_85112390 0.10 ENST00000629253.1
ENST00000539556.6
CIBAR2
CBY1 interacting BAR domain containing 2
chr1_+_12125892 0.10 ENST00000413146.6
TNFRSF8
TNF receptor superfamily member 8
chr3_+_40477107 0.10 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
ZNF619
zinc finger protein 619
chr12_+_2803197 0.09 ENST00000544366.1
FKBP4
FKBP prolyl isomerase 4
chr13_+_112979306 0.09 ENST00000421756.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr12_+_56996151 0.09 ENST00000556850.1
GPR182
G protein-coupled receptor 182
chr13_-_79405784 0.08 ENST00000267229.11
RBM26
RNA binding motif protein 26
chr10_-_27243019 0.08 ENST00000679293.1
ACBD5
acyl-CoA binding domain containing 5
chr6_-_159788439 0.08 ENST00000539948.5
TCP1
t-complex 1
chr2_-_27211888 0.08 ENST00000426119.5
ENST00000412471.5
SLC5A6
solute carrier family 5 member 6
chr1_-_204685700 0.08 ENST00000367177.4
LRRN2
leucine rich repeat neuronal 2
chr11_-_96389857 0.07 ENST00000680532.1
ENST00000681014.1
ENST00000679708.1
ENST00000645439.1
ENST00000645366.1
ENST00000680728.1
ENST00000680859.1
ENST00000679788.1
ENST00000681164.1
ENST00000646818.2
ENST00000680171.1
ENST00000679696.1
ENST00000681200.1
ENST00000679960.1
ENST00000647080.1
ENST00000646050.1
ENST00000681451.1
ENST00000644686.1
ENST00000680052.1
ENST00000679616.1
ENST00000530203.2
CCDC82
coiled-coil domain containing 82
chr10_-_73096974 0.07 ENST00000440381.5
ENST00000263556.3
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr18_-_26546990 0.07 ENST00000578973.1
KCTD1
potassium channel tetramerization domain containing 1
chr12_+_53295506 0.06 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
PFDN5
prefoldin subunit 5
chr7_+_142111739 0.06 ENST00000550469.6
ENST00000477922.3
MGAM2
maltase-glucoamylase 2 (putative)
chr17_+_12789697 0.06 ENST00000262444.13
ARHGAP44
Rho GTPase activating protein 44
chr3_-_50359480 0.06 ENST00000266025.4
TMEM115
transmembrane protein 115
chr3_+_130929998 0.06 ENST00000508297.2
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr14_-_58427114 0.05 ENST00000556007.6
TIMM9
translocase of inner mitochondrial membrane 9
chr8_-_124565699 0.05 ENST00000519168.5
MTSS1
MTSS I-BAR domain containing 1
chr11_-_1585283 0.05 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr20_-_3663399 0.05 ENST00000290417.7
ENST00000319242.8
GFRA4
GDNF family receptor alpha 4
chr15_+_68631988 0.05 ENST00000543950.3
CORO2B
coronin 2B
chr2_+_3389681 0.05 ENST00000457845.4
ENST00000441983.5
TRAPPC12
trafficking protein particle complex 12
chr14_-_58427134 0.04 ENST00000555930.6
TIMM9
translocase of inner mitochondrial membrane 9
chr15_+_51341648 0.04 ENST00000335449.11
ENST00000560215.5
GLDN
gliomedin
chr2_+_96760857 0.04 ENST00000377075.3
CNNM4
cyclin and CBS domain divalent metal cation transport mediator 4
chr16_+_71358713 0.04 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
CALB2
calbindin 2
chr11_-_96389936 0.04 ENST00000680763.1
ENST00000679856.1
ENST00000643839.1
ENST00000645500.1
ENST00000530106.2
CCDC82
coiled-coil domain containing 82
chr5_-_75717368 0.04 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5
POC5 centriolar protein
chr6_-_24489565 0.04 ENST00000230036.2
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_61829281 0.04 ENST00000448607.1
ENST00000421879.5
FADS1
fatty acid desaturase 1
chr17_-_7211808 0.04 ENST00000648658.1
DLG4
discs large MAGUK scaffold protein 4
chr8_+_32548267 0.04 ENST00000356819.7
NRG1
neuregulin 1
chr2_+_227728335 0.03 ENST00000641700.1
SCYGR7
small cysteine and glycine repeat containing 7
chr19_-_1169138 0.03 ENST00000587655.2
SBNO2
strawberry notch homolog 2
chr20_+_56248732 0.03 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr9_-_101383558 0.03 ENST00000674556.1
BAAT
bile acid-CoA:amino acid N-acyltransferase
chr11_-_89876017 0.03 ENST00000329862.6
TRIM64B
tripartite motif containing 64B
chr12_+_30926428 0.03 ENST00000545802.1
TSPAN11
tetraspanin 11
chr1_+_39738866 0.03 ENST00000324379.10
ENST00000356511.6
ENST00000497370.5
ENST00000470213.5
ENST00000372835.9
ENST00000372830.5
PPIE
peptidylprolyl isomerase E
chr21_+_33205279 0.03 ENST00000683941.1
IFNAR2
interferon alpha and beta receptor subunit 2
chr6_+_167271163 0.03 ENST00000503433.5
UNC93A
unc-93 homolog A
chr10_-_73096850 0.03 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr11_+_193078 0.02 ENST00000342878.3
SCGB1C1
secretoglobin family 1C member 1
chr12_+_51238724 0.02 ENST00000449723.7
ENST00000549555.5
ENST00000439799.6
ENST00000412716.8
ENST00000425012.6
DAZAP2
DAZ associated protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 3.3 GO:0097319 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.3 1.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 0.5 GO:0002818 intracellular defense response(GO:0002818)
0.1 0.8 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.7 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.8 GO:1903750 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.6 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.4 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.1 0.4 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 1.6 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.4 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.1 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.9 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 1.6 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.1 GO:0006463 steroid hormone receptor complex assembly(GO:0006463)
0.0 1.6 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0051836 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 2.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 6.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 2.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.0 GO:0042309 homoiothermy(GO:0042309)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.9 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.5 GO:0044194 cytolytic granule(GO:0044194)
0.0 2.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.5 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 2.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.4 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.5 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 4.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 6.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.0 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.8 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling