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Illumina Body Map 2 (GSE30611)

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Results for RARA

Z-value: 1.19

Motif logo

Transcription factors associated with RARA

Gene Symbol Gene ID Gene Info
ENSG00000131759.18 retinoic acid receptor alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARAhg38_v1_chr17_+_40342342_403424100.594.0e-04Click!

Activity profile of RARA motif

Sorted Z-values of RARA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_133276855 3.98 ENST00000486609.1
ENST00000445355.8
ENST00000485491.6
ADAM metallopeptidase domain 8
chr2_-_207166818 3.58 ENST00000423015.5
Kruppel like factor 7
chr22_+_22322452 3.38 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr22_+_22409755 3.33 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr10_-_133276836 3.22 ENST00000415217.7
ADAM metallopeptidase domain 8
chr22_+_22380766 3.11 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr8_-_7018295 3.04 ENST00000327857.7
defensin alpha 3
chr22_+_50185894 3.00 ENST00000380909.9
ENST00000303434.8
TraB domain containing
chr3_-_112499457 2.94 ENST00000334529.10
B and T lymphocyte associated
chr15_+_32717994 2.70 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr19_-_54281145 2.70 ENST00000434421.5
ENST00000391749.4
leukocyte immunoglobulin like receptor B2
chr19_-_4540028 2.66 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chr9_-_37025733 2.51 ENST00000651550.1
paired box 5
chr22_+_44180915 2.45 ENST00000444313.8
ENST00000416291.5
parvin gamma
chrX_+_48676596 2.38 ENST00000450772.5
WASP actin nucleation promoting factor
chr19_-_54281082 2.35 ENST00000314446.10
leukocyte immunoglobulin like receptor B2
chr17_-_63700100 2.33 ENST00000578993.5
ENST00000259006.8
ENST00000583211.5
LIM domain containing 2
chr3_+_38138478 2.29 ENST00000396334.8
ENST00000417037.8
ENST00000652213.1
ENST00000650112.2
ENST00000651800.2
ENST00000421516.3
ENST00000650905.2
MYD88 innate immune signal transduction adaptor
chr19_-_7699466 2.24 ENST00000360067.8
Fc fragment of IgE receptor II
chr15_+_32718476 2.20 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr17_-_8965674 2.16 ENST00000447110.6
ENST00000611902.4
ENST00000616147.4
ENST00000623421.3
phosphoinositide-3-kinase regulatory subunit 5
chr2_-_234497035 2.16 ENST00000390645.2
ENST00000339728.6
ADP ribosylation factor like GTPase 4C
chr21_+_33229883 2.12 ENST00000382264.7
ENST00000342136.9
ENST00000404220.7
interferon alpha and beta receptor subunit 2
chr17_-_63699730 2.10 ENST00000578061.5
LIM domain containing 2
chr3_-_112499358 2.06 ENST00000383680.4
B and T lymphocyte associated
chr16_+_66579448 2.06 ENST00000379486.6
ENST00000268595.3
CKLF like MARVEL transmembrane domain containing 2
chr14_-_106557465 2.02 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr20_-_47785439 2.01 ENST00000437955.1
sulfatase 2
chr16_-_11586903 1.98 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr11_-_59212869 1.96 ENST00000361050.4
macrophage expressed 1
chr1_+_26280059 1.92 ENST00000270792.10
SH3 domain binding glutamate rich protein like 3
chr11_-_88337722 1.92 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr1_+_26280117 1.85 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr4_-_48080172 1.79 ENST00000507351.1
TXK tyrosine kinase
chr22_+_44677044 1.79 ENST00000006251.11
proline rich 5
chr9_+_136886490 1.79 ENST00000247668.7
TNF receptor associated factor 2
chr10_+_17228806 1.76 ENST00000497849.1
vimentin
chr1_-_156816841 1.75 ENST00000368199.8
ENST00000392306.2
SH2 domain containing 2A
chr22_+_44677077 1.73 ENST00000403581.5
proline rich 5
chr6_+_29942523 1.72 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr6_-_30686624 1.72 ENST00000274853.8
protein phosphatase 1 regulatory subunit 18
chr22_-_50529990 1.70 ENST00000425169.1
ENST00000487577.5
ENST00000651401.1
ENST00000252029.8
ENST00000395680.6
ENST00000395681.6
ENST00000651196.1
ENST00000650719.1
ENST00000395678.7
thymidine phosphorylase
chr6_-_30687200 1.70 ENST00000399199.7
protein phosphatase 1 regulatory subunit 18
chr4_-_42152642 1.69 ENST00000502486.6
BEN domain containing 4
chr4_-_25862979 1.64 ENST00000399878.8
SEL1L family member 3
chr3_-_151203201 1.63 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr20_+_45891370 1.62 ENST00000607482.6
ENST00000372459.7
cathepsin A
chr1_+_28914515 1.61 ENST00000644600.1
ENST00000643173.1
ENST00000648181.1
ENST00000650265.1
ENST00000644780.1
ENST00000343067.9
ENST00000643604.1
ENST00000373797.2
erythrocyte membrane protein band 4.1
chr19_+_7669080 1.59 ENST00000629642.1
resistin
chr5_+_175658008 1.58 ENST00000377291.2
histamine receptor H2
chr20_+_45891348 1.57 ENST00000419493.3
cathepsin A
chr11_+_67266437 1.57 ENST00000308595.10
ENST00000526285.1
G protein-coupled receptor kinase 2
chr7_+_143381561 1.56 ENST00000354434.8
zyxin
chr5_+_119354771 1.54 ENST00000503646.1
TNF alpha induced protein 8
chr17_+_14301069 1.54 ENST00000360954.3
heparan sulfate-glucosamine 3-sulfotransferase 3B1
chr6_+_106360668 1.53 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr20_+_45891309 1.53 ENST00000354880.9
ENST00000646241.3
ENST00000191018.9
cathepsin A
chr14_-_24576240 1.52 ENST00000216336.3
cathepsin G
chr17_+_44350437 1.48 ENST00000586443.1
granulin precursor
chr7_+_143381907 1.47 ENST00000392910.6
zyxin
chr17_-_82333942 1.47 ENST00000581691.5
secreted and transmembrane 1
chr5_+_119355313 1.47 ENST00000504642.1
TNF alpha induced protein 8
chr1_+_160739265 1.46 ENST00000368042.7
SLAM family member 7
chr2_+_191678152 1.46 ENST00000409510.5
nucleic acid binding protein 1
chr14_-_106622837 1.46 ENST00000390628.3
immunoglobulin heavy variable 1-58
chr14_-_106108453 1.44 ENST00000632950.2
immunoglobulin heavy variable 5-10-1
chr16_+_527698 1.43 ENST00000219611.7
ENST00000562370.5
ENST00000568988.5
calpain 15
chr6_+_32741382 1.43 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr1_+_11736120 1.38 ENST00000400895.6
ENST00000314340.10
ENST00000376629.8
ENST00000376627.6
ENST00000452018.6
ENST00000510878.1
angiotensin II receptor associated protein
chr17_+_7572818 1.37 ENST00000293831.13
ENST00000582169.5
ENST00000578754.5
ENST00000578495.5
ENST00000585024.5
ENST00000583802.5
ENST00000577269.5
ENST00000584784.5
ENST00000582746.5
ENST00000581621.1
eukaryotic translation initiation factor 4A1
novel transcript
chr11_+_10305065 1.37 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr2_+_191678122 1.36 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr1_+_28914614 1.32 ENST00000645184.1
erythrocyte membrane protein band 4.1
chr10_+_17228515 1.31 ENST00000478746.1
vimentin
chr19_-_1174227 1.31 ENST00000587024.5
ENST00000361757.8
strawberry notch homolog 2
chr2_-_207166159 1.31 ENST00000426163.5
Kruppel like factor 7
chr17_+_38870050 1.30 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr22_+_44676808 1.29 ENST00000624862.3
proline rich 5
chr19_+_17555615 1.28 ENST00000252599.9
collagen beta(1-O)galactosyltransferase 1
chr19_+_827823 1.27 ENST00000233997.4
azurocidin 1
chr1_-_39901996 1.27 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr7_+_139829153 1.24 ENST00000652056.1
thromboxane A synthase 1
chr7_-_143647646 1.24 ENST00000636941.1
TRPM8 channel associated factor 2C
chr1_-_145995713 1.23 ENST00000425134.2
thioredoxin interacting protein
chr2_+_218568809 1.23 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr9_-_127916978 1.22 ENST00000361444.3
ENST00000335791.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr6_+_31571957 1.21 ENST00000454783.5
lymphotoxin alpha
chr1_-_39901861 1.21 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chr22_-_28741783 1.20 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr15_-_90234046 1.19 ENST00000612800.1
calcium and integrin binding 1
chr6_+_31572279 1.19 ENST00000418386.3
lymphotoxin alpha
chr1_+_28914597 1.18 ENST00000349460.9
erythrocyte membrane protein band 4.1
chr8_+_38030496 1.18 ENST00000338825.5
eukaryotic translation initiation factor 4E binding protein 1
chr19_+_7637099 1.17 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
syntaxin binding protein 2
chr16_-_11256192 1.16 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chr1_-_161069666 1.15 ENST00000368016.7
Rho GTPase activating protein 30
chr15_-_90233902 1.14 ENST00000328649.11
ENST00000650306.1
calcium and integrin binding 1
chr7_+_102433519 1.13 ENST00000356387.6
ENST00000478730.7
ENST00000495936.7
ENST00000611770.5
ENST00000403646.8
ORAI calcium release-activated calcium modulator 2
chr6_-_73520441 1.13 ENST00000615060.5
eukaryotic translation elongation factor 1 alpha 1
chr1_-_156816738 1.13 ENST00000368198.7
SH2 domain containing 2A
chr16_-_88686453 1.10 ENST00000332281.6
snail family transcriptional repressor 3
chr11_-_65859282 1.06 ENST00000526975.1
ENST00000531413.5
ENST00000525451.6
cofilin 1
chr2_-_159798234 1.06 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr2_+_218568558 1.05 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr1_-_159925496 1.04 ENST00000368097.9
transgelin 2
chr1_+_206406377 1.04 ENST00000605476.5
SLIT-ROBO Rho GTPase activating protein 2
chr7_-_149028452 1.03 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr17_+_80101562 1.03 ENST00000302262.8
ENST00000577106.5
ENST00000390015.7
alpha glucosidase
chr1_-_161069962 1.03 ENST00000368015.1
Rho GTPase activating protein 30
chrX_-_101407893 1.03 ENST00000676156.1
ENST00000675592.1
ENST00000674634.2
ENST00000649178.1
ENST00000218516.4
galactosidase alpha
chr19_-_49423441 1.03 ENST00000270631.2
parathyroid hormone 2
chr18_-_46072244 1.00 ENST00000589328.5
ENST00000409746.5
proline-serine-threonine phosphatase interacting protein 2
chr1_-_21279520 1.00 ENST00000357071.8
endothelin converting enzyme 1
chr17_-_81512671 0.99 ENST00000679480.1
ENST00000644774.2
ENST00000571721.6
ENST00000575842.5
ENST00000575087.5
ENST00000573283.7
ENST00000571691.6
ENST00000570382.2
actin gamma 1
chr22_+_46762617 0.98 ENST00000380995.5
ENST00000337137.9
ENST00000407381.7
TBC1 domain family member 22A
chr14_+_20469399 0.98 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr3_-_48561114 0.97 ENST00000452531.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr10_+_17228215 0.97 ENST00000544301.7
vimentin
chr11_-_9091589 0.96 ENST00000649792.2
ENST00000520467.5
ENST00000309263.7
signal peptide, CUB domain and EGF like domain containing 2
chr7_+_100148890 0.95 ENST00000341942.9
ENST00000474141.5
ENST00000460732.5
ENST00000441173.1
ENST00000468582.5
ENST00000488241.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr4_-_2934790 0.95 ENST00000508221.5
ENST00000355443.9
ENST00000507555.1
major facilitator superfamily domain containing 10
chr22_+_46577078 0.95 ENST00000431155.1
GRAM domain containing 4
chr22_-_50251210 0.94 ENST00000448072.5
ENST00000216271.10
histone deacetylase 10
chr12_+_53985138 0.93 ENST00000303460.5
homeobox C10
chr1_-_144461647 0.92 ENST00000488031.6
NBPF member 15
chr12_+_51238854 0.90 ENST00000549732.6
ENST00000604900.5
DAZ associated protein 2
chr17_-_37609361 0.90 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr9_+_137277698 0.90 ENST00000357503.3
torsin family 4 member A
chr19_-_18438120 0.90 ENST00000338128.13
ENST00000578352.5
inositol-3-phosphate synthase 1
chr9_+_6757633 0.90 ENST00000401787.7
ENST00000381306.7
lysine demethylase 4C
chr1_+_101236860 0.90 ENST00000475821.2
sphingosine-1-phosphate receptor 1
chr11_-_125111708 0.89 ENST00000531909.5
ENST00000529530.1
transmembrane protein 218
chr10_+_113679159 0.89 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr6_-_110476388 0.89 ENST00000424139.1
ENST00000437378.5
solute carrier family 22 member 16
chr17_+_40341388 0.89 ENST00000394086.7
retinoic acid receptor alpha
chr22_-_31662180 0.88 ENST00000435900.5
phosphatidylserine decarboxylase
chr7_+_98281669 0.88 ENST00000297290.4
brain protein I3
chr22_-_30667795 0.88 ENST00000404885.5
ENST00000403268.1
ENST00000407308.1
ENST00000334679.4
ENST00000342474.4
dual specificity phosphatase 18
chr1_+_171257930 0.88 ENST00000354841.4
flavin containing dimethylaniline monoxygenase 1
chr22_-_31662430 0.87 ENST00000439502.6
phosphatidylserine decarboxylase
chr3_+_43690961 0.87 ENST00000454293.2
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
chr20_-_45891200 0.87 ENST00000372518.5
neuralized E3 ubiquitin protein ligase 2
chr6_-_73520985 0.87 ENST00000676710.1
ENST00000316292.13
ENST00000309268.11
ENST00000610520.5
ENST00000678515.1
ENST00000678703.1
eukaryotic translation elongation factor 1 alpha 1
chr1_-_149103539 0.85 ENST00000615421.4
ENST00000621645.4
NBPF member 9
chr3_-_101513175 0.85 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr19_+_48965304 0.85 ENST00000331825.11
ferritin light chain
chr7_-_5423543 0.84 ENST00000399537.8
trinucleotide repeat containing 18
chr11_-_9091546 0.84 ENST00000450649.6
signal peptide, CUB domain and EGF like domain containing 2
chr6_-_73523757 0.83 ENST00000455918.2
ENST00000677236.1
eukaryotic translation elongation factor 1 alpha 1
chr1_-_161069857 0.83 ENST00000368013.8
Rho GTPase activating protein 30
chr16_+_88453260 0.83 ENST00000319555.8
zinc finger protein, FOG family member 1
chr19_-_4581755 0.83 ENST00000676793.1
semaphorin 6B
chr16_+_68085552 0.82 ENST00000329524.8
nuclear factor of activated T cells 3
chrX_-_49186328 0.81 ENST00000599218.6
ENST00000376317.4
prickle planar cell polarity protein 3
chr1_+_2555639 0.81 ENST00000426449.5
ENST00000434817.5
ENST00000435221.6
TNF receptor superfamily member 14
chr6_+_151036912 0.81 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr17_-_49230728 0.81 ENST00000503902.1
ENST00000512250.1
ENST00000413580.5
ENST00000511066.5
phosphoethanolamine/phosphocholine phosphatase 1
chr13_+_102799322 0.80 ENST00000639132.1
BIVM-ERCC5 readthrough
chr17_+_49210699 0.80 ENST00000225941.6
ABI family member 3
chr3_-_88059042 0.79 ENST00000309534.10
CGG triplet repeat binding protein 1
chr5_+_177304571 0.79 ENST00000503853.1
PRELI domain containing 1
chrX_+_100644183 0.78 ENST00000640889.1
ENST00000373004.5
sushi repeat containing protein X-linked 2
chr19_+_13906255 0.77 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chr5_-_135452318 0.77 ENST00000537858.2
TIFA inhibitor
chr5_-_1801284 0.76 ENST00000505818.1
mitochondrial ribosomal protein L36
chr14_-_91253925 0.76 ENST00000531499.2
G protein-coupled receptor 68
chr2_-_96145431 0.76 ENST00000288943.5
dual specificity phosphatase 2
chr17_-_11997372 0.76 ENST00000322748.7
ENST00000454073.7
ENST00000580306.7
ENST00000580903.1
zinc finger protein 18
chr17_-_49230770 0.76 ENST00000310544.9
phosphoethanolamine/phosphocholine phosphatase 1
chr11_+_65572349 0.76 ENST00000316409.2
ENST00000449319.2
ENST00000530349.2
family with sequence similarity 89 member B
chr1_-_225999312 0.76 ENST00000272091.8
SDE2 telomere maintenance homolog
chr21_-_45542414 0.75 ENST00000311124.9
solute carrier family 19 member 1
chr19_-_48044037 0.74 ENST00000293255.3
calcium binding protein 5
chr16_+_68085861 0.74 ENST00000570212.5
ENST00000562926.5
nuclear factor of activated T cells 3
chr22_+_22668286 0.74 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr19_+_48954850 0.74 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BCL2 associated X, apoptosis regulator
chr7_+_30028357 0.73 ENST00000622102.4
ENST00000258679.11
ENST00000449726.6
ENST00000396257.6
ENST00000396259.5
pleckstrin homology domain containing A8
chr11_-_125111579 0.72 ENST00000532156.5
ENST00000532407.5
ENST00000279968.8
ENST00000527766.5
ENST00000529583.5
ENST00000524373.5
ENST00000527271.5
ENST00000526175.5
ENST00000529609.5
ENST00000682305.1
ENST00000533273.1
transmembrane protein 218
chr10_+_87659839 0.72 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_+_32222415 0.72 ENST00000678420.1
ENST00000678162.1
ENST00000678711.1
ENST00000678883.1
ENST00000677353.1
ENST00000355082.10
eukaryotic translation initiation factor 3 subunit I
chr22_-_19178402 0.72 ENST00000451283.5
solute carrier family 25 member 1
chr11_-_45917867 0.71 ENST00000378750.10
peroxisomal biogenesis factor 16
chr2_-_207167220 0.70 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr17_+_21284701 0.70 ENST00000529517.1
ENST00000627447.1
ENST00000342679.9
mitogen-activated protein kinase kinase 3
chr19_-_12881460 0.70 ENST00000592506.1
deoxyribonuclease 2, lysosomal
chr22_-_21629991 0.70 ENST00000292778.11
ENST00000398873.4
YdjC chitooligosaccharide deacetylase homolog
chr15_+_90872162 0.70 ENST00000680053.1
furin, paired basic amino acid cleaving enzyme
chr19_-_12881429 0.69 ENST00000222219.8
deoxyribonuclease 2, lysosomal
chr1_-_32222322 0.69 ENST00000344461.7
ENST00000373593.5
ENST00000309777.11
transmembrane protein 234
chr16_-_381935 0.68 ENST00000431232.7
ENST00000250930.7
post-glycosylphosphatidylinositol attachment to proteins 6
chr7_-_45921264 0.68 ENST00000613132.5
ENST00000381083.9
ENST00000381086.9
insulin like growth factor binding protein 3
chr1_+_32222393 0.68 ENST00000676679.1
ENST00000678689.1
ENST00000373586.2
ENST00000679290.1
ENST00000677378.1
ENST00000678534.1
ENST00000678968.1
ENST00000678063.1
ENST00000678150.1
ENST00000677198.1
ENST00000677540.1
eukaryotic translation initiation factor 3 subunit I
chr6_-_88166339 0.68 ENST00000369501.3
ENST00000551417.2
cannabinoid receptor 1
chr7_-_81770362 0.68 ENST00000412881.5
hepatocyte growth factor
chr19_+_18571730 0.67 ENST00000596304.5
ENST00000430157.6
ENST00000596273.5
ENST00000442744.7
ENST00000595683.5
ENST00000599256.5
ENST00000595158.5
ENST00000598780.5
ubiquitin A-52 residue ribosomal protein fusion product 1
chr12_-_57846686 0.67 ENST00000548823.1
ENST00000398073.7
CTD small phosphatase 2
chr7_-_151082908 0.66 ENST00000462940.1
ENST00000492838.1
ENST00000392818.7
ENST00000488752.5
ENST00000476627.5
transmembrane and ubiquitin like domain containing 1
chr7_+_107169720 0.66 ENST00000468401.1
ENST00000497535.5
ENST00000485846.5
HMG-box transcription factor 1
chr17_+_80101525 0.66 ENST00000570803.5
alpha glucosidase
chr3_+_43690880 0.66 ENST00000458276.7
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of RARA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:2000309 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000309) positive regulation of thymocyte migration(GO:2000412)
1.6 4.9 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.8 2.4 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.8 2.4 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.6 5.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.6 2.4 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.6 2.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.6 2.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.6 2.8 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 2.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.3 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.4 0.8 GO:0003192 mitral valve formation(GO:0003192)
0.4 1.2 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.4 1.6 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.3 1.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.3 4.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.3 2.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.3 1.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.8 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 0.9 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 1.7 GO:0005985 sucrose metabolic process(GO:0005985)
0.3 0.8 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.3 0.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.7 GO:0002339 B cell selection(GO:0002339) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.2 1.2 GO:0035627 ceramide transport(GO:0035627)
0.2 4.8 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.7 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.7 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.2 0.7 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 4.0 GO:0070307 lens fiber cell development(GO:0070307)
0.2 1.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.5 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.2 2.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 0.6 GO:0036245 cellular response to menadione(GO:0036245)
0.2 0.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.8 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 0.4 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.2 0.6 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.5 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.6 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.2 0.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 3.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 0.7 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 0.7 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 1.7 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.5 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2 0.8 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 1.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 1.1 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 0.6 GO:0051413 response to cortisone(GO:0051413)
0.1 1.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.1 0.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 3.4 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 4.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.4 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 1.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.4 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.8 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 1.0 GO:0046102 inosine metabolic process(GO:0046102) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.6 GO:0009196 dUDP biosynthetic process(GO:0006227) dTDP biosynthetic process(GO:0006233) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dTDP metabolic process(GO:0046072) dUDP metabolic process(GO:0046077)
0.1 1.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 0.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.9 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.6 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 1.2 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.2 GO:0002347 response to tumor cell(GO:0002347)
0.1 1.0 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.8 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.4 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 1.6 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of vitamin D receptor signaling pathway(GO:0070564)
0.1 0.5 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 13.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.3 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.4 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 1.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.7 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.1 0.5 GO:0009624 response to nematode(GO:0009624)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 2.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 1.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.4 GO:0097350 neutrophil clearance(GO:0097350)
0.1 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.5 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.8 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 2.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.1 0.2 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.3 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.1 0.3 GO:0046874 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 2.2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.7 GO:0017085 response to insecticide(GO:0017085)
0.0 1.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.2 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 1.6 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.4 GO:0009838 abscission(GO:0009838)
0.0 5.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.5 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 2.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 5.2 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
0.0 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.5 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 4.8 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.4 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.9 GO:1902603 carnitine transmembrane transport(GO:1902603)
0.0 0.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 3.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 1.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 2.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.5 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 1.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0051464 positive regulation of cortisol secretion(GO:0051464) positive regulation of glucocorticoid secretion(GO:2000851)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 2.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 2.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.5 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 3.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.6 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.5 2.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5 4.7 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.4 1.8 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.4 2.8 GO:0070876 SOSS complex(GO:0070876)
0.2 4.8 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.2 1.5 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.2 0.8 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 0.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 4.8 GO:0031932 TORC2 complex(GO:0031932)
0.2 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.2 2.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 1.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.6 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 4.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.2 GO:0044194 cytolytic granule(GO:0044194)
0.1 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 13.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 0.9 GO:0070449 elongin complex(GO:0070449)
0.1 2.0 GO:0032433 filopodium tip(GO:0032433)
0.1 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.1 3.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 1.0 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 6.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 3.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 2.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.6 GO:0030175 filopodium(GO:0030175)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.0 GO:0032396 MHC class Ib protein binding(GO:0023029) inhibitory MHC class I receptor activity(GO:0032396)
0.6 1.8 GO:0005174 CD40 receptor binding(GO:0005174)
0.6 2.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.6 1.7 GO:0016154 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.6 1.7 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.5 1.6 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.5 4.0 GO:1990254 keratin filament binding(GO:1990254)
0.5 1.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 2.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.4 1.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.4 4.9 GO:0016015 morphogen activity(GO:0016015)
0.3 1.0 GO:0016936 galactoside binding(GO:0016936)
0.3 5.3 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3 1.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.2 1.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.2 2.2 GO:0019863 IgE binding(GO:0019863)
0.2 0.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.8 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.2 0.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.2 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.4 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.2 0.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 4.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.5 GO:0004615 phosphomannomutase activity(GO:0004615)
0.2 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.9 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 2.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:0090541 MIT domain binding(GO:0090541)
0.1 1.6 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.8 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 1.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0004798 thymidylate kinase activity(GO:0004798)
0.1 0.7 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 12.5 GO:0043621 protein self-association(GO:0043621)
0.1 0.3 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 1.2 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.6 GO:0047238 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 15.0 GO:0003823 antigen binding(GO:0003823)
0.1 0.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.2 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.7 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.2 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.6 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0070181 polyol transmembrane transporter activity(GO:0015166) small ribosomal subunit rRNA binding(GO:0070181)
0.0 3.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.4 GO:0050699 WW domain binding(GO:0050699)
0.0 1.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.5 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 4.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 3.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 15.4 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 4.4 GO:0005125 cytokine activity(GO:0005125)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 4.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.8 PID BMP PATHWAY BMP receptor signaling
0.1 4.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 5.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 5.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 5.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID ATM PATHWAY ATM pathway
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 3.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 6.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 1.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 4.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 6.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.7 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 3.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.0 REACTOME DEFENSINS Genes involved in Defensins
0.1 5.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 5.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex