ISMARA results: RBPJ

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Illumina Body Map 2 (GSE30611)

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Results for RBPJ

Z-value: 1.57

Motif logo

Transcription factors associated with RBPJ

Gene Symbol	Gene ID	Gene Info
RBPJ Ensembl NCBI GeneCards UniProt	ENSG00000168214.21	recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RBPJ	hg38_v1_chr4_+_26343132_26343151	0.49	4.7e-03	Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_-_52950992 Show fit	9.49	ENST00000343279.8 ENST00000399304.7 ENST00000395631.6 ENST00000341590.8	FERMT2 Ensembl NCBI GeneCards UniProt Show fit	fermitin family member 2
chr8_-_79767462 Show fit	8.48	ENST00000674295.1 ENST00000518733.1 ENST00000674418.1 ENST00000674358.1 ENST00000354724.8	HEY1 Ensembl NCBI GeneCards UniProt Show fit	hes related family bHLH transcription factor with YRPW motif 1
chr3_-_100993507 Show fit	6.68	ENST00000284322.10	ABI3BP Ensembl NCBI GeneCards UniProt Show fit	ABI family member 3 binding protein
chr3_-_100993409 Show fit	6.17	ENST00000471714.6	ABI3BP Ensembl NCBI GeneCards UniProt Show fit	ABI family member 3 binding protein
chr3_-_100993448 Show fit	6.17	ENST00000495063.6 ENST00000486770.7 ENST00000530539.2	ABI3BP Ensembl NCBI GeneCards UniProt Show fit	ABI family member 3 binding protein
chr3_+_142723999 Show fit	6.13	ENST00000476941.6 ENST00000273482.10	TRPC1 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 1
chr12_+_12785652 Show fit	5.30	ENST00000356591.5	APOLD1 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein L domain containing 1
chr11_+_118607598 Show fit	5.02	ENST00000600882.6 ENST00000356063.9	PHLDB1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 1
chr20_+_31637905 Show fit	4.93	ENST00000376075.4	COX4I2 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase subunit 4I2
chr6_+_125749623 Show fit	4.75	ENST00000368364.4	HEY2 Ensembl NCBI GeneCards UniProt Show fit	hes related family bHLH transcription factor with YRPW motif 2
chr20_+_44582549 Show fit	4.09	ENST00000372886.6	PKIG Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor gamma
chr7_-_120858066 Show fit	4.01	ENST00000222747.8	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr7_+_94394886 Show fit	4.00	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr9_+_70043840 Show fit	3.98	ENST00000377182.5	MAMDC2 Ensembl NCBI GeneCards UniProt Show fit	MAM domain containing 2
chr6_-_93419545 Show fit	3.84	ENST00000369297.1 ENST00000369303.9 ENST00000680224.1 ENST00000681532.1 ENST00000679565.1	EPHA7 Ensembl NCBI GeneCards UniProt Show fit	EPH receptor A7
chr17_-_41624541 Show fit	3.79	ENST00000540235.5 ENST00000311208.13	KRT17 Ensembl NCBI GeneCards UniProt Show fit	keratin 17
chr11_+_112961247 Show fit	3.64	ENST00000621518.4 ENST00000618266.4 ENST00000615112.4 ENST00000615285.4 ENST00000619839.4 ENST00000401611.6 ENST00000621128.4	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr8_+_67952028 Show fit	3.56	ENST00000288368.5	PREX2 Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr10_-_95441015 Show fit	3.38	ENST00000371241.5 ENST00000354106.7 ENST00000371239.5 ENST00000361941.7 ENST00000277982.9 ENST00000371245.7	SORBS1 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 1
chr9_+_99821846 Show fit	3.30	ENST00000338488.8 ENST00000618101.4	NR4A3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4 group A member 3
chr12_+_65278919 Show fit	3.30	ENST00000538045.5 ENST00000642411.1 ENST00000535239.5 ENST00000614640.4	MSRB3 Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase B3
chr12_+_65279092 Show fit	3.23	ENST00000646299.1	MSRB3 Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase B3
chr12_+_65279445 Show fit	3.20	ENST00000642404.1	MSRB3 Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase B3
chr8_-_22232020 Show fit	3.19	ENST00000454243.7 ENST00000321613.7	PHYHIP Ensembl NCBI GeneCards UniProt Show fit	phytanoyl-CoA 2-hydroxylase interacting protein
chr6_+_30884353 Show fit	3.07	ENST00000428153.6 ENST00000376568.8 ENST00000452441.5 ENST00000515219.5	DDR1 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 1
chr6_-_75493629 Show fit	3.04	ENST00000393004.6	FILIP1 Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr17_-_58529344 Show fit	3.04	ENST00000317268.7	SEPTIN4 Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr9_+_99821876 Show fit	3.01	ENST00000395097.7	NR4A3 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 4 group A member 3
chr11_+_112961402 Show fit	3.00	ENST00000613217.4 ENST00000316851.12 ENST00000620046.4 ENST00000531044.5 ENST00000529356.5	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr8_-_79767843 Show fit	3.00	ENST00000337919.9	HEY1 Ensembl NCBI GeneCards UniProt Show fit	hes related family bHLH transcription factor with YRPW motif 1
chr6_-_75493773 Show fit	2.99	ENST00000237172.12	FILIP1 Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1
chr6_+_30884063 Show fit	2.90	ENST00000511510.5 ENST00000376569.7 ENST00000376570.8 ENST00000504927.5	DDR1 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 1
chr17_-_58529303 Show fit	2.83	ENST00000580844.5	SEPTIN4 Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr10_-_37857582 Show fit	2.82	ENST00000395867.8 ENST00000611278.4	ZNF248 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 248
chr1_-_39639626 Show fit	2.79	ENST00000372852.4	HEYL Ensembl NCBI GeneCards UniProt Show fit	hes related family bHLH transcription factor with YRPW motif like
chr12_+_6200759 Show fit	2.74	ENST00000645565.1 ENST00000382515.7	CD9 Ensembl NCBI GeneCards UniProt Show fit	CD9 molecule
chr17_-_58529277 Show fit	2.56	ENST00000579371.5	SEPTIN4 Ensembl NCBI GeneCards UniProt Show fit	septin 4
chr12_+_6828377 Show fit	2.50	ENST00000290510.10	P3H3 Ensembl NCBI GeneCards UniProt Show fit	prolyl 3-hydroxylase 3
chr12_-_16606795 Show fit	2.50	ENST00000447609.5	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr11_+_111541326 Show fit	2.47	ENST00000530962.5 ENST00000528924.4	LAYN Ensembl NCBI GeneCards UniProt Show fit	layilin
chr3_-_45915698 Show fit	2.45	ENST00000539217.5	LZTFL1 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper transcription factor like 1
chr11_-_119340816 Show fit	2.45	ENST00000528368.3	C1QTNF5 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 5
chr19_+_3094348 Show fit	2.36	ENST00000078429.9	GNA11 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha 11
chr19_+_50203607 Show fit	2.35	ENST00000642316.2 ENST00000425460.6 ENST00000440075.6 ENST00000376970.6 ENST00000599920.5	MYH14 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 14
chr11_+_112961480 Show fit	2.35	ENST00000621850.4	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr4_-_86594037 Show fit	2.32	ENST00000641050.1 ENST00000641831.1 ENST00000515400.3 ENST00000641391.1 ENST00000641157.1 ENST00000641737.1 ENST00000502302.6 ENST00000640527.1 ENST00000512046.2 ENST00000513186.7	MAPK10 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 10
chr2_+_48568981 Show fit	2.32	ENST00000394754.5	STON1-GTF2A1L Ensembl NCBI GeneCards UniProt Show fit	STON1-GTF2A1L readthrough
chr4_-_185657520 Show fit	2.31	ENST00000438278.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr3_+_159852933 Show fit	2.31	ENST00000482804.1	SCHIP1 Ensembl NCBI GeneCards UniProt Show fit	schwannomin interacting protein 1
chr16_-_70685975 Show fit	2.31	ENST00000338779.11	MTSS2 Ensembl NCBI GeneCards UniProt Show fit	MTSS I-BAR domain containing 2
chr2_+_43774033 Show fit	2.29	ENST00000260605.12 ENST00000406852.7 ENST00000398823.6 ENST00000605786.5	DYNC2LI1 Ensembl NCBI GeneCards UniProt Show fit	dynein cytoplasmic 2 light intermediate chain 1
chr4_+_155667198 Show fit	2.28	ENST00000296518.11	GUCY1A1 Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr7_-_16465728 Show fit	2.24	ENST00000307068.5	SOSTDC1 Ensembl NCBI GeneCards UniProt Show fit	sclerostin domain containing 1
chr7_-_120858303 Show fit	2.12	ENST00000415871.5 ENST00000430985.1	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr16_-_70685791 Show fit	2.08	ENST00000616026.4	MTSS2 Ensembl NCBI GeneCards UniProt Show fit	MTSS I-BAR domain containing 2
chr1_-_84893166 Show fit	2.06	ENST00000370611.4	LPAR3 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 3
chr16_-_57797764 Show fit	2.02	ENST00000465878.6 ENST00000561524.5	KIFC3 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C3
chr4_+_155667096 Show fit	1.99	ENST00000393832.7	GUCY1A1 Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr11_+_118607579 Show fit	1.98	ENST00000530708.4	PHLDB1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 1
chr10_+_31319125 Show fit	1.93	ENST00000320985.14 ENST00000560721.6 ENST00000558440.5 ENST00000424869.6 ENST00000542815.7	ZEB1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 1
chr14_+_51489112 Show fit	1.90	ENST00000356218.8	FRMD6 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 6
chr10_-_33334898 Show fit	1.87	ENST00000395995.5	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr10_-_33334625 Show fit	1.86	ENST00000374875.5 ENST00000374822.8 ENST00000374867.7	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr14_-_92748570 Show fit	1.85	ENST00000553918.1 ENST00000555699.5 ENST00000334869.9 ENST00000553802.5 ENST00000554397.5 ENST00000554919.5 ENST00000554080.5 ENST00000553371.1 ENST00000557434.5 ENST00000393218.6	LGMN Ensembl NCBI GeneCards UniProt Show fit	legumain
chr7_-_22220226 Show fit	1.85	ENST00000420196.5	RAPGEF5 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 5
chr10_+_122560639 Show fit	1.85	ENST00000344338.7 ENST00000330163.8 ENST00000652446.2 ENST00000666315.1 ENST00000368955.7 ENST00000368909.7 ENST00000368956.6 ENST00000619379.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr16_+_23302292 Show fit	1.83	ENST00000343070.7	SCNN1B Ensembl NCBI GeneCards UniProt Show fit	sodium channel epithelial 1 subunit beta
chr17_-_28726186 Show fit	1.81	ENST00000292090.8	TLCD1 Ensembl NCBI GeneCards UniProt Show fit	TLC domain containing 1
chr12_-_16607087 Show fit	1.80	ENST00000540445.5	LMO3 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 3
chr15_+_57599411 Show fit	1.80	ENST00000569089.1	MYZAP Ensembl NCBI GeneCards UniProt Show fit	myocardial zonula adherens protein
chr10_-_33334382 Show fit	1.78	ENST00000374823.9 ENST00000374821.9 ENST00000374816.7	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr10_-_107164692 Show fit	1.76	ENST00000263054.11	SORCS1 Ensembl NCBI GeneCards UniProt Show fit	sortilin related VPS10 domain containing receptor 1
chr3_+_194136138 Show fit	1.74	ENST00000232424.4	HES1 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 1
chr3_-_19934189 Show fit	1.74	ENST00000295824.14	EFHB Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain family member B
chr11_-_119340544 Show fit	1.71	ENST00000530681.2	C1QTNF5 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 5
chr16_-_1611985 Show fit	1.71	ENST00000426508.7	IFT140 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 140
chr3_+_156142962 Show fit	1.70	ENST00000471742.5	KCNAB1 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr10_+_111077021 Show fit	1.69	ENST00000280155.4	ADRA2A Ensembl NCBI GeneCards UniProt Show fit	adrenoceptor alpha 2A
chr2_+_149330506 Show fit	1.69	ENST00000334166.9	LYPD6 Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 6
chr10_-_37858037 Show fit	1.68	ENST00000395873.7 ENST00000357328.8 ENST00000395874.2	ZNF248 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 248
chr15_+_59438149 Show fit	1.61	ENST00000288228.10 ENST00000559628.5 ENST00000557914.5 ENST00000560474.5	FAM81A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 81 member A
chr18_+_68715191 Show fit	1.59	ENST00000578970.5 ENST00000582371.5 ENST00000584775.5	CCDC102B Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 102B
chr4_+_155667654 Show fit	1.58	ENST00000513574.1	GUCY1A1 Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr5_-_116536458 Show fit	1.55	ENST00000510263.5	SEMA6A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chr12_-_48865863 Show fit	1.52	ENST00000309739.6	RND1 Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 1
chr1_+_61404076 Show fit	1.49	ENST00000357977.5	NFIA Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I A
chr5_-_140564245 Show fit	1.49	ENST00000412920.7 ENST00000511201.2 ENST00000354402.9 ENST00000356738.6	APBB3 Ensembl NCBI GeneCards UniProt Show fit	amyloid beta precursor protein binding family B member 3
chr16_-_57798008 Show fit	1.46	ENST00000421376.6	KIFC3 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C3
chr5_+_38445539 Show fit	1.45	ENST00000397210.7 ENST00000506135.5 ENST00000508131.5	EGFLAM Ensembl NCBI GeneCards UniProt Show fit	EGF like, fibronectin type III and laminin G domains
chr1_-_85404494 Show fit	1.44	ENST00000633113.1	DDAH1 Ensembl NCBI GeneCards UniProt Show fit	dimethylarginine dimethylaminohydrolase 1
chr9_-_137028878 Show fit	1.41	ENST00000625103.1 ENST00000614293.4	ABCA2 Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily A member 2
chr5_+_178895892 Show fit	1.38	ENST00000520660.5 ENST00000361362.7 ENST00000520805.5	ZFP2 Ensembl NCBI GeneCards UniProt Show fit	ZFP2 zinc finger protein
chr4_+_183905266 Show fit	1.33	ENST00000308497.9	STOX2 Ensembl NCBI GeneCards UniProt Show fit	storkhead box 2
chr10_+_100999287 Show fit	1.33	ENST00000370220.1	LZTS2 Ensembl NCBI GeneCards UniProt Show fit	leucine zipper tumor suppressor 2
chr10_-_33335074 Show fit	1.32	ENST00000432372.6	NRP1 Ensembl NCBI GeneCards UniProt Show fit	neuropilin 1
chr2_+_169733811 Show fit	1.31	ENST00000392647.7	KLHL23 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 23
chrX_+_106802660 Show fit	1.26	ENST00000357242.10 ENST00000310452.6 ENST00000481617.6 ENST00000276175.7	TBC1D8B Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family member 8B
chr17_-_41624803 Show fit	1.25	ENST00000463128.5	KRT17 Ensembl NCBI GeneCards UniProt Show fit	keratin 17
chr6_-_134052594 Show fit	1.25	ENST00000275230.6	SLC2A12 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 12
chr16_-_10182754 Show fit	1.21	ENST00000396573.6 ENST00000675398.1	GRIN2A Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor NMDA type subunit 2A
chr5_+_147878703 Show fit	1.19	ENST00000296694.5	SCGB3A2 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 3A member 2
chr10_+_122560751 Show fit	1.18	ENST00000338354.10 ENST00000664692.1 ENST00000653442.1 ENST00000664974.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr17_-_38735577 Show fit	1.17	ENST00000610747.1	PCGF2 Ensembl NCBI GeneCards UniProt Show fit	polycomb group ring finger 2
chr11_-_32430811 Show fit	1.16	ENST00000379079.8 ENST00000530998.5	WT1 Ensembl NCBI GeneCards UniProt Show fit	WT1 transcription factor
chr19_-_45792755 Show fit	1.14	ENST00000377735.7 ENST00000270223.7	DMWD Ensembl NCBI GeneCards UniProt Show fit	DM1 locus, WD repeat containing
chr4_-_119628007 Show fit	1.12	ENST00000420633.1 ENST00000394439.5	PDE5A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 5A
chr1_-_1000139 Show fit	1.11	ENST00000428771.6	HES4 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 4
chr10_+_113679523 Show fit	1.09	ENST00000345633.8 ENST00000614447.4 ENST00000369321.6	CASP7 Ensembl NCBI GeneCards UniProt Show fit	caspase 7
chr2_+_218959635 Show fit	1.09	ENST00000302625.6	CDK5R2 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 5 regulatory subunit 2
chr7_+_128862841 Show fit	1.07	ENST00000249289.5 ENST00000492758.1	ATP6V1F Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit F
chr10_+_113679839 Show fit	1.07	ENST00000369318.8 ENST00000369315.5	CASP7 Ensembl NCBI GeneCards UniProt Show fit	caspase 7
chr3_-_100840109 Show fit	1.06	ENST00000533795.5	ABI3BP Ensembl NCBI GeneCards UniProt Show fit	ABI family member 3 binding protein
chr8_-_100336184 Show fit	1.05	ENST00000519527.5 ENST00000522369.5	RNF19A Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr4_-_175812236 Show fit	1.03	ENST00000505375.5	GPM6A Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6A
chr16_+_53703963 Show fit	1.00	ENST00000636218.1 ENST00000637001.1 ENST00000471389.6 ENST00000637969.1 ENST00000640179.1	FTO Ensembl NCBI GeneCards UniProt Show fit	FTO alpha-ketoglutarate dependent dioxygenase
chr20_+_31475278 Show fit	1.00	ENST00000201979.3	REM1 Ensembl NCBI GeneCards UniProt Show fit	RRAD and GEM like GTPase 1
chr11_+_66744618 Show fit	1.00	ENST00000524551.5 ENST00000525908.6 ENST00000540737.7 ENST00000527634.5	C11orf80 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 80
chr16_-_57798091 Show fit	0.99	ENST00000562503.5	KIFC3 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C3
chr4_-_175812746 Show fit	0.99	ENST00000393658.6	GPM6A Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6A
chr7_-_120857124 Show fit	0.98	ENST00000441017.5 ENST00000424710.5 ENST00000433758.5	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr15_-_43879835 Show fit	0.95	ENST00000636859.1	FRMD5 Ensembl NCBI GeneCards UniProt Show fit	FERM domain containing 5
chr1_+_43389874 Show fit	0.95	ENST00000372450.8	SZT2 Ensembl NCBI GeneCards UniProt Show fit	SZT2 subunit of KICSTOR complex
chr1_-_1000088 Show fit	0.95	ENST00000304952.11	HES4 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 4
chr19_-_40218339 Show fit	0.93	ENST00000311308.6	TTC9B Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 9B
chr7_+_30771388 Show fit	0.93	ENST00000265299.6	MINDY4 Ensembl NCBI GeneCards UniProt Show fit	MINDY lysine 48 deubiquitinase 4
chr4_+_26319636 Show fit	0.92	ENST00000342295.6 ENST00000506956.5 ENST00000512671.6 ENST00000345843.8	RBPJ Ensembl NCBI GeneCards UniProt Show fit	recombination signal binding protein for immunoglobulin kappa J region
chr6_-_32224060 Show fit	0.89	ENST00000375023.3	NOTCH4 Ensembl NCBI GeneCards UniProt Show fit	notch receptor 4
chr11_-_119340914 Show fit	0.89	ENST00000634633.1	C1QTNF5 Ensembl NCBI GeneCards UniProt Show fit	C1q and TNF related 5
chr16_-_10182394 Show fit	0.88	ENST00000330684.4	GRIN2A Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor NMDA type subunit 2A
chr5_+_178941186 Show fit	0.88	ENST00000320129.7 ENST00000519564.2	ZNF454 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 454
chr16_-_53703810 Show fit	0.87	ENST00000569716.1 ENST00000562588.5 ENST00000621565.5 ENST00000562230.5 ENST00000563746.5 ENST00000568653.7 ENST00000647211.2	RPGRIP1L Ensembl NCBI GeneCards UniProt Show fit	RPGRIP1 like
chr1_+_43389889 Show fit	0.87	ENST00000562955.2 ENST00000634258.3	SZT2 Ensembl NCBI GeneCards UniProt Show fit	SZT2 subunit of KICSTOR complex
chr5_-_88877967 Show fit	0.86	ENST00000508610.5 ENST00000636294.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr5_-_124744513 Show fit	0.84	ENST00000504926.5	ZNF608 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 608
chr1_+_14945775 Show fit	0.84	ENST00000400797.3	KAZN Ensembl NCBI GeneCards UniProt Show fit	kazrin, periplakin interacting protein
chr11_-_83682385 Show fit	0.83	ENST00000426717.6	DLG2 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 2
chr9_+_706841 Show fit	0.82	ENST00000382293.7	KANK1 Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 1
chrX_+_147911910 Show fit	0.82	ENST00000370475.9	FMR1 Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr17_+_50274447 Show fit	0.81	ENST00000507382.2	TMEM92 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 92
chr8_-_126557691 Show fit	0.80	ENST00000652209.1	LRATD2 Ensembl NCBI GeneCards UniProt Show fit	LRAT domain containing 2
chr2_-_40430257 Show fit	0.79	ENST00000408028.6 ENST00000332839.8 ENST00000406391.2 ENST00000405901.7	SLC8A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 8 member A1
chr3_-_132037800 Show fit	0.79	ENST00000617767.4	CPNE4 Ensembl NCBI GeneCards UniProt Show fit	copine 4
chr12_-_31792290 Show fit	0.77	ENST00000340398.5	H3-5 Ensembl NCBI GeneCards UniProt Show fit	H3.5 histone
chr8_-_86230360 Show fit	0.76	ENST00000419776.2 ENST00000297524.8	SLC7A13 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 13
chr5_-_116536428 Show fit	0.76	ENST00000515009.5	SEMA6A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chr20_-_46308485 Show fit	0.75	ENST00000537909.4	CDH22 Ensembl NCBI GeneCards UniProt Show fit	cadherin 22
chr1_-_999981 Show fit	0.75	ENST00000484667.2	HES4 Ensembl NCBI GeneCards UniProt Show fit	hes family bHLH transcription factor 4
chr2_-_218270099 Show fit	0.73	ENST00000248450.9 ENST00000444053.5	AAMP Ensembl NCBI GeneCards UniProt Show fit	angio associated migratory cell protein
chr11_-_101583985 Show fit	0.72	ENST00000344327.8	TRPC6 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 6
chr2_+_37950476 Show fit	0.71	ENST00000402091.3	RMDN2 Ensembl NCBI GeneCards UniProt Show fit	regulator of microtubule dynamics 2
chr1_-_43389768 Show fit	0.71	ENST00000372455.4 ENST00000372457.9 ENST00000290663.10	MED8 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 8
chr2_+_218270392 Show fit	0.70	ENST00000248451.7 ENST00000273077.9	PNKD Ensembl NCBI GeneCards UniProt Show fit	PNKD metallo-beta-lactamase domain containing
chr3_-_171771295 Show fit	0.70	ENST00000418087.1	PLD1 Ensembl NCBI GeneCards UniProt Show fit	phospholipase D1
chr12_+_106582996 Show fit	0.69	ENST00000392842.6	RFX4 Ensembl NCBI GeneCards UniProt Show fit	regulatory factor X4
chr1_+_113390495 Show fit	0.69	ENST00000307546.14	MAGI3 Ensembl NCBI GeneCards UniProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr1_-_180502536 Show fit	0.66	ENST00000367595.4	ACBD6 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA binding domain containing 6
chr17_+_2796404 Show fit	0.65	ENST00000366401.8 ENST00000254695.13 ENST00000542807.1	RAP1GAP2 Ensembl NCBI GeneCards UniProt Show fit	RAP1 GTPase activating protein 2
chr13_-_24922788 Show fit	0.65	ENST00000381884.9	CENPJ Ensembl NCBI GeneCards UniProt Show fit	centromere protein J
chr1_-_147172456 Show fit	0.65	ENST00000254101.4	PRKAB2 Ensembl NCBI GeneCards UniProt Show fit	protein kinase AMP-activated non-catalytic subunit beta 2
chr8_+_22056966 Show fit	0.65	ENST00000517804.5	DMTN Ensembl NCBI GeneCards UniProt Show fit	dematin actin binding protein
chr11_+_66744831 Show fit	0.63	ENST00000642265.1 ENST00000532565.6	C11orf80 Ensembl NCBI GeneCards UniProt Show fit	chromosome 11 open reading frame 80
chr19_+_34926892 Show fit	0.63	ENST00000303586.11 ENST00000601142.2 ENST00000439785.5 ENST00000601540.5 ENST00000601957.5	ZNF30 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 30
chr13_-_20230970 Show fit	0.63	ENST00000644667.1 ENST00000646108.1	GJB6 Ensembl NCBI GeneCards UniProt Show fit	gap junction protein beta 6
chrX_+_147911943 Show fit	0.62	ENST00000621453.4 ENST00000218200.12 ENST00000370471.7 ENST00000440235.6 ENST00000370477.5 ENST00000621987.4	FMR1 Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1
chr1_+_239719542 Show fit	0.62	ENST00000448020.1	CHRM3 Ensembl NCBI GeneCards UniProt Show fit	cholinergic receptor muscarinic 3
chr1_-_223364059 Show fit	0.62	ENST00000343846.7 ENST00000484758.6 ENST00000344029.6 ENST00000366878.9 ENST00000494793.6 ENST00000681285.1 ENST00000680429.1 ENST00000681669.1 ENST00000681305.1	SUSD4 Ensembl NCBI GeneCards UniProt Show fit	sushi domain containing 4
chrX_-_153830527 Show fit	0.62	ENST00000393758.7 ENST00000544474.5	PDZD4 Ensembl NCBI GeneCards UniProt Show fit	PDZ domain containing 4
chr16_-_53703883 Show fit	0.61	ENST00000262135.9 ENST00000564374.5 ENST00000566096.5	RPGRIP1L Ensembl NCBI GeneCards UniProt Show fit	RPGRIP1 like
chr19_+_39997031 Show fit	0.61	ENST00000599504.5 ENST00000596894.5 ENST00000601138.5 ENST00000347077.9 ENST00000600094.5	ZNF546 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 546
chr3_+_37975773 Show fit	0.59	ENST00000436654.1	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr19_-_38899800 Show fit	0.59	ENST00000414941.5 ENST00000358931.9 ENST00000392081.6	SIRT2 Ensembl NCBI GeneCards UniProt Show fit	sirtuin 2
chr6_-_41163182 Show fit	0.57	ENST00000338469.3	TREM2 Ensembl NCBI GeneCards UniProt Show fit	triggering receptor expressed on myeloid cells 2
chr1_-_23369813 Show fit	0.56	ENST00000314011.9	ZNF436 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 436
chr21_-_6499202 Show fit	0.56	ENST00000619610.2 ENST00000610664.5 ENST00000639996.1	U2AF1L5 Ensembl NCBI GeneCards UniProt Show fit	U2 small nuclear RNA auxiliary factor 1 like 5
chr6_-_31542339 Show fit	0.55	ENST00000458640.5	DDX39B Ensembl NCBI GeneCards UniProt Show fit	DExD-box helicase 39B
chr8_+_106726012 Show fit	0.53	ENST00000449762.6 ENST00000297447.10	OXR1 Ensembl NCBI GeneCards UniProt Show fit	oxidation resistance 1
chr10_+_122560679 Show fit	0.52	ENST00000657942.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr16_-_57802401 Show fit	0.51	ENST00000569112.5 ENST00000445690.7 ENST00000562311.5 ENST00000379655.8	KIFC3 Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C3
chr11_+_64285839 Show fit	0.50	ENST00000438980.7 ENST00000540370.1	GPR137 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 137
chr17_-_81128873 Show fit	0.49	ENST00000572339.5	AATK Ensembl NCBI GeneCards UniProt Show fit	apoptosis associated tyrosine kinase
chr5_-_138178599 Show fit	0.49	ENST00000454473.5 ENST00000418329.5 ENST00000254900.10 ENST00000230901.9 ENST00000402931.5 ENST00000411594.6 ENST00000430331.1	BRD8 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 8
chr4_-_119627631 Show fit	0.48	ENST00000264805.9	PDE5A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 5A
chr11_+_64285219 Show fit	0.45	ENST00000377702.8	GPR137 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 137
chr18_-_72638510 Show fit	0.45	ENST00000581073.1	CBLN2 Ensembl NCBI GeneCards UniProt Show fit	cerebellin 2 precursor
chr15_+_67125707 Show fit	0.44	ENST00000540846.6	SMAD3 Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr8_+_66432475 Show fit	0.43	ENST00000415254.5 ENST00000396623.8	ADHFE1 Ensembl NCBI GeneCards UniProt Show fit	alcohol dehydrogenase iron containing 1
chr15_-_77696142 Show fit	0.42	ENST00000561030.5	LINGO1 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat and Ig domain containing 1
chrX_+_153411472 Show fit	0.42	ENST00000338647.7	ZFP92 Ensembl NCBI GeneCards UniProt Show fit	ZFP92 zinc finger protein
chr7_+_90709530 Show fit	0.41	ENST00000406263.5	CDK14 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 14
chr3_-_151249114 Show fit	0.41	ENST00000424796.6	P2RY14 Ensembl NCBI GeneCards UniProt Show fit	purinergic receptor P2Y14
chr12_-_4649043 Show fit	0.40	ENST00000545990.6 ENST00000228850.6	AKAP3 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 3
chr3_+_46407558 Show fit	0.39	ENST00000357392.4 ENST00000400880.3 ENST00000433848.1	CCRL2 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor like 2
chr9_-_133609325 Show fit	0.39	ENST00000673969.1	FAM163B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 163 member B
chr1_+_81699665 Show fit	0.39	ENST00000359929.7	ADGRL2 Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L2
chr8_+_106726115 Show fit	0.38	ENST00000521592.5	OXR1 Ensembl NCBI GeneCards UniProt Show fit	oxidation resistance 1
chr10_-_48251757 Show fit	0.38	ENST00000305531.3	FRMPD2 Ensembl NCBI GeneCards UniProt Show fit	FERM and PDZ domain containing 2
chr2_-_144430934 Show fit	0.38	ENST00000638087.1 ENST00000638007.1	ZEB2 Ensembl NCBI GeneCards UniProt Show fit	zinc finger E-box binding homeobox 2
chrX_-_74614612 Show fit	0.37	ENST00000349225.2 ENST00000332687.11	RLIM Ensembl NCBI GeneCards UniProt Show fit	ring finger protein, LIM domain interacting
chr1_-_204166334 Show fit	0.37	ENST00000272190.9	REN Ensembl NCBI GeneCards UniProt Show fit	renin
chr17_+_31094880 Show fit	0.37	ENST00000487476.5 ENST00000356175.7	NF1 Ensembl NCBI GeneCards UniProt Show fit	neurofibromin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.4	16.2	GO:0061027	umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
1.7	6.8	GO:0021649	vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
1.3	6.3	GO:0032765	positive regulation of mast cell cytokine production(GO:0032765)
0.7	9.7	GO:0030091	protein repair(GO:0030091)
0.6	1.7	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.5	5.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.4	1.3	GO:0070446	cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.4	1.7	GO:0035625	negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4	2.1	GO:0033058	directional locomotion(GO:0033058)
0.4	4.3	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4	1.1	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.4	6.9	GO:0006828	manganese ion transport(GO:0006828)
0.4	7.0	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.3	1.0	GO:0042245	RNA repair(GO:0042245)
0.3	1.6	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.3	6.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.3	3.0	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.3	1.2	GO:0072302	negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.3	1.4	GO:0044830	modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.3	2.8	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.3	0.8	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3	1.9	GO:0003383	apical constriction(GO:0003383)
0.3	9.5	GO:0033622	integrin activation(GO:0033622)
0.3	2.2	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3	1.8	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.3	3.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.3	1.0	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	2.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.2	4.0	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.2	0.7	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2	3.8	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.2	3.6	GO:0043589	skin morphogenesis(GO:0043589)
0.2	1.4	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2	0.6	GO:0002588	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2	4.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2	2.7	GO:0009414	response to water deprivation(GO:0009414)
0.2	5.0	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.2	4.5	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2	5.3	GO:0042118	endothelial cell activation(GO:0042118)
0.2	2.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.4	GO:0015993	molecular hydrogen transport(GO:0015993)
0.1	7.1	GO:0010842	retina layer formation(GO:0010842)
0.1	2.4	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	2.1	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	0.7	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1	3.4	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.1	0.4	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	2.5	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.1	22.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	1.7	GO:0060539	diaphragm development(GO:0060539)
0.1	1.6	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.3	GO:1903567	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1	0.7	GO:0061511	centriole elongation(GO:0061511)
0.1	2.3	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.1	0.8	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.1	0.6	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1	0.7	GO:0003138	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	1.4	GO:0000052	citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.1	1.5	GO:0043584	nose development(GO:0043584)
0.1	0.7	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.1	0.9	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	1.9	GO:0010447	response to acidic pH(GO:0010447)
0.0	9.0	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	4.0	GO:0070206	protein trimerization(GO:0070206)
0.0	0.4	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	1.5	GO:0072189	ureter development(GO:0072189)
0.0	2.1	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.4	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	1.7	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.0	2.4	GO:0071625	vocalization behavior(GO:0071625)
0.0	1.6	GO:0046710	GDP metabolic process(GO:0046710)
0.0	1.3	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	1.1	GO:0015988	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0	0.3	GO:0048539	bone marrow development(GO:0048539)
0.0	3.6	GO:0008344	adult locomotory behavior(GO:0008344)
0.0	1.8	GO:0055078	sodium ion homeostasis(GO:0055078)
0.0	0.3	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	1.2	GO:0003407	neural retina development(GO:0003407)
0.0	0.2	GO:1905068	arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) regulation of ephrin receptor signaling pathway(GO:1901187) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0	0.8	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.2	GO:1902748	positive regulation of lens fiber cell differentiation(GO:1902748)
0.0	0.1	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	0.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.3	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0	0.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.8	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.0	0.3	GO:0006853	carnitine shuttle(GO:0006853)
0.0	0.1	GO:0072156	distal tubule morphogenesis(GO:0072156)
0.0	0.0	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.6	GO:0051602	response to electrical stimulus(GO:0051602)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	4.0	GO:0005584	collagen type I trimer(GO:0005584)
0.7	6.8	GO:0097443	sorting endosome(GO:0097443)
0.7	3.4	GO:0005899	insulin receptor complex(GO:0005899)
0.6	21.5	GO:0005614	interstitial matrix(GO:0005614)
0.4	7.0	GO:0045180	basal cortex(GO:0045180)
0.3	2.4	GO:0097513	myosin II filament(GO:0097513)
0.3	1.4	GO:1902737	dendritic filopodium(GO:1902737)
0.3	1.9	GO:0036021	endolysosome lumen(GO:0036021)
0.3	5.3	GO:0005915	zonula adherens(GO:0005915)
0.2	4.3	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.2	1.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	1.8	GO:1990130	Iml1 complex(GO:1990130)
0.2	1.7	GO:1990635	proximal dendrite(GO:1990635)
0.2	3.6	GO:0042589	zymogen granule membrane(GO:0042589)
0.2	9.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.2	1.1	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1	1.5	GO:0005879	axonemal microtubule(GO:0005879)
0.1	3.6	GO:0016580	Sin3 complex(GO:0016580)
0.1	1.7	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	0.7	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.1	1.3	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.6	GO:0032279	asymmetric synapse(GO:0032279)
0.1	2.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.6	GO:0089701	U2AF(GO:0089701)
0.1	0.7	GO:0001739	sex chromatin(GO:0001739)
0.1	1.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	2.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	2.8	GO:0042629	mast cell granule(GO:0042629)
0.1	0.8	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	2.7	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.8	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.6	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.0	10.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.2	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	4.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	3.5	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.4	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	2.4	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.7	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.5	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.8	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	12.6	GO:0043235	receptor complex(GO:0043235)
0.0	0.3	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	3.5	GO:0005882	intermediate filament(GO:0005882)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	4.9	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	2.0	GO:0030175	filopodium(GO:0030175)
0.0	2.8	GO:0043296	apical junction complex(GO:0043296)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.8	19.0	GO:0035939	microsatellite binding(GO:0035939)
1.2	3.6	GO:0035375	zymogen binding(GO:0035375)
1.1	9.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.6	6.8	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.6	2.4	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.6	1.7	GO:0031696	alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
0.6	5.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.5	6.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.5	2.5	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.5	1.5	GO:0031862	prostanoid receptor binding(GO:0031862)
0.4	1.3	GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.4	1.7	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.4	1.1	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3	6.0	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3	3.8	GO:0008046	axon guidance receptor activity(GO:0008046)
0.3	4.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	7.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.3	1.0	GO:0035514	DNA demethylase activity(GO:0035514)
0.2	2.2	GO:0098821	BMP receptor activity(GO:0098821)
0.2	0.7	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2	7.3	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2	4.9	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	1.4	GO:0016403	dimethylargininase activity(GO:0016403)
0.2	2.3	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	2.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.2	1.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.1	1.4	GO:0034046	poly(G) binding(GO:0034046)
0.1	2.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.1	4.5	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1	9.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	3.8	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	18.1	GO:0005518	collagen binding(GO:0005518)
0.1	2.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	1.8	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	1.9	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.8	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1	0.4	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.1	0.6	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	2.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.6	GO:0050733	RS domain binding(GO:0050733)
0.1	0.6	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1	0.3	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1	0.6	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.1	1.7	GO:0070402	NADPH binding(GO:0070402)
0.1	2.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	8.5	GO:0001618	virus receptor activity(GO:0001618)
0.1	0.7	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	1.3	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.4	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.1	2.8	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	1.6	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	2.0	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	2.7	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532) cupric ion binding(GO:1903135)
0.0	1.0	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	1.1	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.7	GO:0003680	AT DNA binding(GO:0003680)
0.0	1.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.4	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	1.1	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	3.7	GO:0005178	integrin binding(GO:0005178)
0.0	1.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	1.9	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	1.1	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.4	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	15.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	2.4	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	7.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	3.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	4.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	23.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	6.5	PID FGF PATHWAY	FGF signaling pathway
0.1	4.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	3.4	PID INSULIN PATHWAY	Insulin Pathway
0.1	2.7	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	4.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	2.1	PID REELIN PATHWAY	Reelin signaling pathway
0.0	2.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	1.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	2.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	1.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	1.4	PID BMP PATHWAY	BMP receptor signaling
0.0	6.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.3	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	1.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.7	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	6.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	8.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.9	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	13.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	8.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	2.9	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	5.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	2.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	2.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	2.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	3.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	2.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	1.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	1.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	2.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	11.1	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	2.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	1.3	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation

Results for RBPJ

Z-value: 1.57

Motif logo

Transcription factors associated with RBPJ

Activity-expression correlation:

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: