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Illumina Body Map 2 (GSE30611)

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Results for RELA

Z-value: 2.49

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
ENSG00000173039.19 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg38_v1_chr11_-_65662931_656629720.631.1e-04Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_9760893 16.92 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr4_-_76023489 14.79 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_-_31582415 12.39 ENST00000429299.3
ENST00000446745.2
lymphotoxin beta
chr2_-_89143133 12.36 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr6_+_137867241 11.78 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr6_+_137867414 10.30 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr11_+_102317450 9.81 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr6_+_144150492 9.65 ENST00000367568.5
syntaxin 11
chr11_+_102317542 9.23 ENST00000532808.5
baculoviral IAP repeat containing 3
chr1_-_186680411 9.09 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr4_+_73869385 9.02 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr22_-_37149900 8.91 ENST00000216223.10
interleukin 2 receptor subunit beta
chr3_+_101827982 8.74 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKB inhibitor zeta
chr17_-_35880350 8.65 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr5_-_150412743 8.57 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr11_+_102317492 8.54 ENST00000673846.1
baculoviral IAP repeat containing 3
chr10_+_30434021 7.83 ENST00000542547.5
mitogen-activated protein kinase kinase kinase 8
chr17_+_42288464 7.78 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr12_+_52051402 7.75 ENST00000243050.5
ENST00000550763.1
ENST00000394825.6
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
nuclear receptor subfamily 4 group A member 1
chr6_+_29723340 7.64 ENST00000334668.8
major histocompatibility complex, class I, F
chr1_+_202010575 7.62 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr19_+_45001430 7.50 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr6_+_29723421 7.36 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr10_+_30434176 7.30 ENST00000263056.6
ENST00000375322.2
mitogen-activated protein kinase kinase kinase 8
chr14_+_103123452 7.07 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr10_+_102394488 7.06 ENST00000369966.8
nuclear factor kappa B subunit 2
chr6_+_32637396 7.03 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr2_+_227813834 7.01 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr6_+_32637419 6.96 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr4_-_73998669 6.93 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr4_-_74099187 6.89 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr17_+_42288429 6.74 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr4_-_74038681 6.66 ENST00000296026.4
C-X-C motif chemokine ligand 3
chr19_-_17847962 6.51 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr19_+_41877267 6.51 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79a molecule
chr14_-_35404650 6.38 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr22_-_37244237 6.38 ENST00000401529.3
ENST00000249071.11
Rac family small GTPase 2
chr11_-_128522189 6.37 ENST00000526145.6
ETS proto-oncogene 1, transcription factor
chr19_-_46625037 6.16 ENST00000596260.1
ENST00000594275.1
ENST00000597185.1
ENST00000598865.5
ENST00000291294.7
prostaglandin I2 receptor
chr1_+_202010615 6.13 ENST00000446188.1
E74 like ETS transcription factor 3
chr4_-_76007501 6.10 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr10_+_30434116 5.92 ENST00000415139.5
mitogen-activated protein kinase kinase kinase 8
chr7_+_22727147 5.91 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr11_-_5249836 5.84 ENST00000632727.1
ENST00000330597.5
hemoglobin subunit gamma 1
chr17_+_16415553 5.62 ENST00000338560.12
transient receptor potential cation channel subfamily V member 2
chr11_-_128522285 5.58 ENST00000319397.6
ENST00000535549.5
ETS proto-oncogene 1, transcription factor
chr14_+_75522427 5.55 ENST00000286639.8
basic leucine zipper ATF-like transcription factor
chr17_-_63699730 5.31 ENST00000578061.5
LIM domain containing 2
chr5_+_119268689 5.25 ENST00000274456.6
TNF alpha induced protein 8
chr4_-_76036060 4.94 ENST00000306621.8
C-X-C motif chemokine ligand 11
chr11_+_130159773 4.90 ENST00000278742.6
ST14 transmembrane serine protease matriptase
chr11_-_58578096 4.87 ENST00000528954.5
ENST00000528489.1
leupaxin
chr3_+_157436842 4.77 ENST00000295927.4
pentraxin 3
chr22_-_37244417 4.68 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr7_-_16804987 4.63 ENST00000401412.5
ENST00000419304.7
anterior gradient 2, protein disulphide isomerase family member
chr6_+_106086316 4.62 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr22_-_19525369 4.60 ENST00000403084.1
ENST00000413119.2
claudin 5
chr6_-_32668368 4.52 ENST00000399084.5
major histocompatibility complex, class II, DQ beta 1
chr7_+_17299234 4.49 ENST00000637807.1
novel protein
chr9_-_133479075 4.48 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr17_-_63699162 4.45 ENST00000582055.1
LIM domain containing 2
chr19_+_35449584 4.44 ENST00000246549.2
free fatty acid receptor 2
chr7_+_17298642 4.42 ENST00000242057.9
aryl hydrocarbon receptor
chr11_-_128522264 4.38 ENST00000531611.5
ETS proto-oncogene 1, transcription factor
chr3_-_157160751 4.38 ENST00000461804.5
cyclin L1
chr3_-_158672612 4.36 ENST00000264265.4
latexin
chr11_-_75351686 4.35 ENST00000360025.7
arrestin beta 1
chr7_+_143381286 4.34 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
zyxin
chr9_+_124291935 4.32 ENST00000546191.5
NIMA related kinase 6
chr22_+_36922040 4.26 ENST00000406230.5
colony stimulating factor 2 receptor subunit beta
chr6_-_29559724 4.25 ENST00000377050.5
ubiquitin D
chr3_+_137998735 4.17 ENST00000343735.8
claudin 18
chr19_+_10271093 4.07 ENST00000423829.2
ENST00000588645.1
ENST00000264832.8
intercellular adhesion molecule 1
chr1_-_159925496 4.04 ENST00000368097.9
transgelin 2
chr2_-_43226594 3.90 ENST00000282388.4
ZFP36 ring finger protein like 2
chrX_-_30577759 3.89 ENST00000378962.4
TLR adaptor interacting with endolysosomal SLC15A4
chr3_+_111859180 3.87 ENST00000412622.5
ENST00000431670.7
pleckstrin homology like domain family B member 2
chr7_-_93890744 3.80 ENST00000650573.1
ENST00000222543.11
ENST00000649913.1
ENST00000647793.1
tissue factor pathway inhibitor 2
chr10_-_71773513 3.80 ENST00000394957.8
V-set immunoregulatory receptor
chr21_+_33403466 3.79 ENST00000405436.5
interferon gamma receptor 2
chr7_+_143381561 3.78 ENST00000354434.8
zyxin
chr19_-_6591103 3.75 ENST00000423145.7
ENST00000245903.4
CD70 molecule
chr10_+_30434602 3.70 ENST00000413724.5
mitogen-activated protein kinase kinase kinase 8
chr11_+_118883884 3.66 ENST00000292174.5
C-X-C motif chemokine receptor 5
chr6_-_30744537 3.60 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr11_-_75351609 3.57 ENST00000420843.7
arrestin beta 1
chr3_-_112133218 3.56 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr13_+_108269629 3.56 ENST00000430559.5
ENST00000375887.9
TNF superfamily member 13b
chr1_+_203305510 3.53 ENST00000290551.5
BTG anti-proliferation factor 2
chr5_-_139462701 3.52 ENST00000618155.3
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr10_+_102395693 3.49 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr19_-_11577632 3.44 ENST00000590420.1
ENST00000648477.1
acid phosphatase 5, tartrate resistant
chr21_+_33403391 3.38 ENST00000290219.11
ENST00000381995.5
interferon gamma receptor 2
chr12_-_57110284 3.35 ENST00000543873.6
ENST00000554663.5
ENST00000557635.5
signal transducer and activator of transcription 6
chr19_+_17527250 3.29 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
niban apoptosis regulator 3
chr11_-_96343170 3.25 ENST00000524717.6
mastermind like transcriptional coactivator 2
chr1_+_46175079 3.20 ENST00000372003.6
tetraspanin 1
chr1_-_209652329 3.14 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr12_+_6946468 3.13 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr1_+_26543106 3.10 ENST00000530003.5
ribosomal protein S6 kinase A1
chr6_-_73520985 3.09 ENST00000676710.1
ENST00000316292.13
ENST00000309268.11
ENST00000610520.5
ENST00000678515.1
ENST00000678703.1
eukaryotic translation elongation factor 1 alpha 1
chr19_-_11577434 3.09 ENST00000590832.1
acid phosphatase 5, tartrate resistant
chr11_+_122655712 3.09 ENST00000284273.6
ubiquitin associated and SH3 domain containing B
chr4_-_184474037 3.08 ENST00000510814.5
ENST00000507523.5
ENST00000506230.5
interferon regulatory factor 2
chr4_-_40629842 3.08 ENST00000295971.12
RNA binding motif protein 47
chr3_+_53161120 3.07 ENST00000394729.6
ENST00000330452.8
ENST00000652449.1
protein kinase C delta
chr14_-_68979436 3.06 ENST00000193403.10
actinin alpha 1
chr1_+_100352451 3.05 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
cell division cycle 14A
chr3_+_53161241 3.04 ENST00000477794.2
ENST00000650739.1
protein kinase C delta
chr1_-_204467216 2.99 ENST00000367184.2
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_-_73142308 2.98 ENST00000409418.9
FCH and double SH3 domains 2
chr17_+_78169127 2.97 ENST00000590201.1
synaptogyrin 2
chr6_-_32853618 2.97 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr6_-_32853813 2.96 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr18_+_3252267 2.94 ENST00000536605.1
ENST00000580887.5
myosin light chain 12A
chr6_-_73521549 2.91 ENST00000676547.1
eukaryotic translation elongation factor 1 alpha 1
chr17_+_42288076 2.90 ENST00000546010.6
signal transducer and activator of transcription 5A
chr2_+_236569817 2.89 ENST00000272928.4
atypical chemokine receptor 3
chr2_+_218880844 2.87 ENST00000258411.8
Wnt family member 10A
chr1_-_202159977 2.85 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr17_+_40318237 2.85 ENST00000394089.6
ENST00000425707.7
retinoic acid receptor alpha
chr1_-_155990062 2.82 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr5_+_119268744 2.80 ENST00000388882.5
TNF alpha induced protein 8
chr1_-_153963462 2.80 ENST00000368621.5
ENST00000368623.7
ENST00000621013.4
solute carrier family 39 member 1
chr3_+_111859284 2.78 ENST00000498699.5
pleckstrin homology like domain family B member 2
chr1_-_155978144 2.77 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chr17_-_4949037 2.76 ENST00000572383.1
profilin 1
chr17_+_78168565 2.76 ENST00000225777.8
ENST00000585591.5
ENST00000589711.1
ENST00000588282.5
ENST00000589168.1
synaptogyrin 2
chr1_-_153963505 2.73 ENST00000356205.9
ENST00000537590.5
solute carrier family 39 member 1
chr8_+_38901757 2.70 ENST00000616834.1
pleckstrin homology domain containing A2
chr10_-_6062349 2.69 ENST00000379959.8
interleukin 2 receptor subunit alpha
chr12_+_93572664 2.66 ENST00000551556.2
suppressor of cytokine signaling 2
chr1_-_161199044 2.65 ENST00000367995.3
ENST00000367996.6
ADAM metallopeptidase with thrombospondin type 1 motif 4
chr2_+_161136901 2.59 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr14_+_51847145 2.57 ENST00000615906.4
G protein subunit gamma 2
chr19_+_51225059 2.54 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr3_+_141487008 2.51 ENST00000286364.9
ENST00000452898.2
RAS p21 protein activator 2
chr1_+_111227699 2.50 ENST00000369748.9
chitinase 3 like 2
chr19_+_2476118 2.46 ENST00000215631.9
ENST00000587345.1
growth arrest and DNA damage inducible beta
chr14_+_75522531 2.45 ENST00000555504.1
basic leucine zipper ATF-like transcription factor
chr20_-_4815100 2.41 ENST00000379376.2
Ras association domain family member 2
chr17_-_7687427 2.40 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr19_-_47231191 2.39 ENST00000439096.3
BCL2 binding component 3
chr2_+_96536743 2.37 ENST00000673792.1
ENST00000357485.8
AT-rich interaction domain 5A
chr1_+_111227610 2.36 ENST00000369744.6
chitinase 3 like 2
chr4_+_73836667 2.35 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr18_-_12884151 2.34 ENST00000591115.5
ENST00000309660.10
ENST00000353319.8
ENST00000327283.7
protein tyrosine phosphatase non-receptor type 2
chr11_-_73142032 2.34 ENST00000311172.11
ENST00000409314.5
FCH and double SH3 domains 2
chr10_-_124092445 2.31 ENST00000346248.7
carbohydrate sulfotransferase 15
chr3_-_177197157 2.29 ENST00000630833.2
ENST00000450267.5
ENST00000431674.5
TBL1X receptor 1
chr2_+_201122477 2.28 ENST00000425030.1
CASP8 and FADD like apoptosis regulator
chr6_+_135181268 2.27 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr4_-_184474518 2.26 ENST00000393593.8
interferon regulatory factor 2
chr10_-_124092390 2.26 ENST00000628426.1
carbohydrate sulfotransferase 15
chr19_+_41860236 2.23 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
ribosomal protein S19
chr19_-_7702139 2.22 ENST00000346664.9
Fc fragment of IgE receptor II
chr1_-_202160577 2.20 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
protein tyrosine phosphatase non-receptor type 7
chr2_+_201183120 2.18 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr5_-_159099684 2.16 ENST00000380654.8
EBF transcription factor 1
chr7_-_101237791 2.15 ENST00000308344.10
claudin 15
chr9_+_124291975 2.15 ENST00000422297.5
NIMA related kinase 6
chr21_+_42403874 2.14 ENST00000319294.11
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chrX_-_132219473 2.13 ENST00000620646.4
RAP2C, member of RAS oncogene family
chrX_-_132219439 2.13 ENST00000370874.2
RAP2C, member of RAS oncogene family
chr19_-_7702124 2.13 ENST00000597921.6
Fc fragment of IgE receptor II
chr14_-_68979076 2.13 ENST00000538545.6
ENST00000684639.1
actinin alpha 1
chr1_-_235866867 2.12 ENST00000389793.7
lysosomal trafficking regulator
chr1_+_100719734 2.12 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
vascular cell adhesion molecule 1
chr1_+_66354375 2.12 ENST00000480109.2
phosphodiesterase 4B
chr16_+_50696999 2.10 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr5_-_159099745 2.08 ENST00000517373.1
EBF transcription factor 1
chr17_+_7834200 2.07 ENST00000448097.7
lysine demethylase 6B
chr1_+_156153568 2.06 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A
chr14_-_68979251 2.03 ENST00000438964.6
ENST00000679147.1
actinin alpha 1
chr14_-_68796054 2.03 ENST00000557022.1
ZFP36 ring finger protein like 1
chr12_-_48865863 2.02 ENST00000309739.6
Rho family GTPase 1
chr1_+_26545833 2.02 ENST00000531382.5
ribosomal protein S6 kinase A1
chr4_-_119628007 1.98 ENST00000420633.1
ENST00000394439.5
phosphodiesterase 5A
chr19_+_40717091 1.97 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr8_+_38901327 1.96 ENST00000519640.5
ENST00000617275.5
pleckstrin homology domain containing A2
chr19_+_40775154 1.94 ENST00000594436.5
ENST00000597784.5
MIA SH3 domain containing
chr1_-_41484680 1.93 ENST00000372587.5
endothelin 2
chr8_-_102655707 1.93 ENST00000285407.11
Kruppel like factor 10
chr10_-_43408787 1.93 ENST00000356053.7
heterogeneous nuclear ribonucleoprotein F
chr4_-_119628791 1.92 ENST00000354960.8
phosphodiesterase 5A
chr1_-_64966284 1.92 ENST00000671929.1
ENST00000673046.1
ENST00000672247.1
Janus kinase 1
chr2_+_161160420 1.89 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr1_-_155188351 1.87 ENST00000462317.5
mucin 1, cell surface associated
chr1_+_206470463 1.85 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr6_+_137867214 1.85 ENST00000421450.1
TNF alpha induced protein 3
chr1_-_153963262 1.84 ENST00000417348.2
solute carrier family 39 member 1
chr7_-_101237827 1.83 ENST00000611078.4
claudin 15
chr12_+_65278643 1.75 ENST00000355192.8
ENST00000308259.10
ENST00000540804.5
ENST00000535664.5
ENST00000541189.5
methionine sulfoxide reductase B3
chr11_-_3840942 1.73 ENST00000351018.5
ras homolog family member G
chr15_+_43792305 1.72 ENST00000249786.9
ENST00000409960.6
ENST00000409646.5
ENST00000339624.9
ENST00000409291.5
ENST00000402131.5
ENST00000403425.5
ENST00000430901.1
small EDRK-rich factor 2
chr1_-_112707056 1.72 ENST00000369633.6
ENST00000425265.6
ENST00000369632.6
ENST00000436685.6
ENST00000484054.3
ENST00000369636.6
ENST00000369637.5
ENST00000339083.12
ENST00000285735.6
ENST00000369638.6
ras homolog family member C
chr4_+_168497044 1.72 ENST00000505667.6
palladin, cytoskeletal associated protein
chr22_-_20437785 1.72 ENST00000622235.5
ENST00000623402.1
scavenger receptor class F member 2
chr12_+_65279092 1.71 ENST00000646299.1
methionine sulfoxide reductase B3
chr15_+_57591891 1.71 ENST00000267853.10
ENST00000380569.6
myocardial zonula adherens protein
GRINL1A complex locus 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 23.9 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
3.2 6.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
3.0 9.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
2.9 8.6 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
2.6 10.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
2.2 8.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.1 32.0 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
2.0 5.9 GO:0046967 cytosol to ER transport(GO:0046967)
1.9 17.4 GO:0000255 allantoin metabolic process(GO:0000255)
1.9 1.9 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.8 7.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
1.7 8.6 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
1.7 17.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.7 20.4 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.6 27.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
1.6 4.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
1.5 4.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
1.5 6.1 GO:2000753 regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
1.5 15.0 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.5 4.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.5 5.9 GO:1990637 response to prolactin(GO:1990637)
1.3 5.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
1.2 12.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.2 2.4 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
1.2 41.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
1.0 3.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.0 7.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.9 4.6 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.9 4.6 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.9 8.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.9 4.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.9 3.5 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.9 4.3 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.8 7.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.8 4.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.8 3.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.7 4.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.7 2.2 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.7 5.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.7 13.7 GO:0060056 mammary gland involution(GO:0060056)
0.7 2.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.7 5.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.7 2.0 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.7 3.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.6 2.4 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.6 7.8 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.6 2.9 GO:0033590 response to cobalamin(GO:0033590)
0.5 2.5 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.5 19.8 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.5 2.9 GO:0048733 sebaceous gland development(GO:0048733)
0.5 2.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 7.3 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.4 1.3 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.4 6.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.4 0.9 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.4 7.1 GO:0051601 exocyst localization(GO:0051601)
0.4 1.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.4 2.4 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.4 3.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 5.2 GO:0030091 protein repair(GO:0030091)
0.4 1.2 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.4 3.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.4 6.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 4.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.4 1.1 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 3.9 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.4 4.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4 2.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.3 1.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.3 10.5 GO:0051639 actin filament network formation(GO:0051639)
0.3 12.4 GO:0003094 glomerular filtration(GO:0003094)
0.3 1.3 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.3 1.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 2.4 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.3 9.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.3 27.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 0.9 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 3.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 3.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 5.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 4.0 GO:0060613 fat pad development(GO:0060613)
0.2 6.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 4.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.2 1.5 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 5.8 GO:0015671 oxygen transport(GO:0015671)
0.2 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.2 7.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 1.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 2.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 23.7 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.2 2.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 1.7 GO:0036343 psychomotor behavior(GO:0036343)
0.2 2.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.3 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.2 0.2 GO:2000152 negative regulation of protein deubiquitination(GO:0090086) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of ubiquitin-specific protease activity(GO:2000152) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.8 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.2 3.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 3.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 5.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 2.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 3.3 GO:0048535 lymph node development(GO:0048535)
0.1 3.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 1.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 6.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 1.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 6.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 3.5 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.1 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) positive regulation of chemokine biosynthetic process(GO:0045080) interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.6 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 4.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.9 GO:0060751 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1 13.3 GO:0035690 cellular response to drug(GO:0035690)
0.1 3.5 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 1.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 3.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 4.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 1.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 2.1 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 9.2 GO:0042100 B cell proliferation(GO:0042100)
0.1 3.7 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0060154 response to cycloheximide(GO:0046898) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.6 GO:0006828 manganese ion transport(GO:0006828)
0.1 4.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.0 GO:0016322 neuron remodeling(GO:0016322)
0.1 4.0 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 2.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 1.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.9 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 8.1 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 0.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 2.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.5 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 5.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 6.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 1.3 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 4.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.8 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 2.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.4 GO:0034349 glial cell apoptotic process(GO:0034349)
0.0 0.8 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0032625 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 1.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.0 0.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 1.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.5 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 3.0 GO:1905037 autophagosome organization(GO:1905037)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 1.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 6.0 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 1.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 2.0 GO:0006901 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.7 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 3.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0070671 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 3.6 GO:2001020 regulation of response to DNA damage stimulus(GO:2001020)
0.0 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 2.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 2.2 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:2000543 primitive streak formation(GO:0090009) positive regulation of gastrulation(GO:2000543)
0.0 0.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
2.5 12.4 GO:0071754 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.8 17.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.4 4.3 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
1.4 15.0 GO:0042612 MHC class I protein complex(GO:0042612)
1.4 27.1 GO:0042611 MHC protein complex(GO:0042611) MHC class II protein complex(GO:0042613)
1.3 6.5 GO:0019815 B cell receptor complex(GO:0019815)
1.0 6.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.9 4.4 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.8 5.9 GO:0042825 TAP complex(GO:0042825)
0.7 2.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.5 2.5 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.5 18.4 GO:0031143 pseudopodium(GO:0031143)
0.5 4.8 GO:0005610 laminin-5 complex(GO:0005610)
0.4 6.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 5.8 GO:0005833 hemoglobin complex(GO:0005833)
0.4 2.9 GO:0043196 varicosity(GO:0043196)
0.3 1.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.3 2.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 1.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.3 2.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 6.9 GO:0097342 ripoptosome(GO:0097342)
0.3 3.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 4.8 GO:0045180 basal cortex(GO:0045180)
0.2 2.7 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 7.1 GO:0000145 exocyst(GO:0000145)
0.2 12.7 GO:0002102 podosome(GO:0002102)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 2.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 0.8 GO:0043291 RAVE complex(GO:0043291)
0.1 11.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 2.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 5.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 59.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 11.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 1.8 GO:0030008 TRAPP complex(GO:0030008)
0.1 4.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0000125 PCAF complex(GO:0000125)
0.1 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 8.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 2.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 12.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 4.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 11.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 4.3 GO:0016235 aggresome(GO:0016235)
0.1 4.3 GO:0031201 SNARE complex(GO:0031201)
0.0 11.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.6 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 5.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0033643 host cell part(GO:0033643)
0.0 3.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 18.9 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 2.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 1.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 2.9 GO:0016459 myosin complex(GO:0016459)
0.0 27.6 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 54.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 4.8 GO:0000922 spindle pole(GO:0000922)
0.0 5.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 8.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 25.8 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.9 32.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.6 7.9 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
2.6 20.9 GO:0046979 TAP2 binding(GO:0046979)
2.3 11.6 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.8 9.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
1.8 7.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.7 8.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.7 8.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.5 4.4 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
1.4 7.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
1.1 18.5 GO:0032395 MHC class II receptor activity(GO:0032395)
1.1 22.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.9 4.3 GO:0004914 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.7 4.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.7 41.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.7 6.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 4.6 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.6 2.3 GO:0097677 STAT family protein binding(GO:0097677)
0.6 5.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.6 6.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.6 26.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.5 4.8 GO:0001849 complement component C1q binding(GO:0001849)
0.5 3.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 24.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.5 3.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4 4.3 GO:0019863 IgE binding(GO:0019863)
0.4 1.3 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.4 6.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.4 7.5 GO:0008199 ferric iron binding(GO:0008199)
0.4 6.4 GO:0004568 chitinase activity(GO:0004568)
0.3 1.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 2.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.3 2.4 GO:1990763 arrestin family protein binding(GO:1990763)
0.3 2.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 8.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 6.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.3 5.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 10.5 GO:0017166 vinculin binding(GO:0017166)
0.2 6.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 1.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 3.0 GO:0001727 lipid kinase activity(GO:0001727)
0.2 3.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 2.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 4.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 4.6 GO:0002162 dystroglycan binding(GO:0002162)
0.2 3.6 GO:0045159 myosin II binding(GO:0045159)
0.2 2.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 4.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 2.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 2.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 12.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 2.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.9 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.2 1.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 9.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 2.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 6.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 6.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 4.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 5.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 6.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 6.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.9 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 4.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 2.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 3.9 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 5.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 4.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 7.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 3.1 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 7.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 6.1 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 1.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 28.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 2.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 6.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 11.5 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 1.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 4.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 8.0 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 4.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.2 GO:0042805 actinin binding(GO:0042805)
0.0 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 5.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.4 GO:0000149 SNARE binding(GO:0000149)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 3.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 5.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 24.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.1 86.0 PID CD40 PATHWAY CD40/CD40L signaling
0.5 8.7 PID IL23 PATHWAY IL23-mediated signaling events
0.5 5.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 9.0 ST STAT3 PATHWAY STAT3 Pathway
0.4 7.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.4 4.3 PID IL5 PATHWAY IL5-mediated signaling events
0.4 36.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 9.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 31.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 2.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.3 23.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 29.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 4.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 11.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 9.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 6.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 13.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.2 4.8 ST ADRENERGIC Adrenergic Pathway
0.1 11.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 6.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 4.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 2.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 2.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 17.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 34.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 3.4 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 5.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 ST GAQ PATHWAY G alpha q Pathway
0.0 3.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 2.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 4.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 15.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.0 77.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.9 55.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.8 27.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.7 3.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6 14.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.6 14.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.6 14.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.6 6.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.5 24.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.5 6.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 9.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 16.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 10.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.3 12.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 14.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 5.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 10.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 2.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 5.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 8.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 6.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 7.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 4.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 2.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 1.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 6.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 5.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 12.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 4.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 7.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 3.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 6.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 4.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 5.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 8.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 5.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 2.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.2 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 3.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.4 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 1.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.3 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres