Project

Illumina Body Map 2 (GSE30611)

Navigation
Downloads

Results for RELB

Z-value: 0.99

Motif logo

logo of

Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
RELB
ENSG00000104856.14 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg38_v1_chr19_+_45001430_450015250.144.5e-01Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74099187 3.56 ENST00000508487.3
CXCL2
C-X-C motif chemokine ligand 2
chr4_+_77605807 3.09 ENST00000682537.1
CXCL13
C-X-C motif chemokine ligand 13
chr19_+_41877267 2.66 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule
chr11_+_18266254 2.64 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
SAA1
serum amyloid A1
chr2_-_88947820 2.38 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr6_-_29559724 2.26 ENST00000377050.5
UBD
ubiquitin D
chr2_-_89320146 2.19 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39
chr2_+_89913982 2.01 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr16_+_85899121 1.75 ENST00000268638.10
ENST00000565552.1
IRF8
interferon regulatory factor 8
chr2_-_89100352 1.69 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr2_+_90159840 1.68 ENST00000377032.5
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr19_-_4540028 1.63 ENST00000306390.7
LRG1
leucine rich alpha-2-glycoprotein 1
chr17_-_7114813 1.60 ENST00000254850.11
ASGR2
asialoglycoprotein receptor 2
chr1_+_116754422 1.56 ENST00000369478.4
ENST00000369477.1
CD2
CD2 molecule
chr2_-_89010515 1.55 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr1_-_173917281 1.54 ENST00000367698.4
SERPINC1
serpin family C member 1
chr15_+_32717994 1.49 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
GREM1
gremlin 1, DAN family BMP antagonist
chr22_+_22720615 1.48 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr6_+_32741382 1.43 ENST00000374940.4
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr9_-_133479075 1.43 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
SLC2A6
solute carrier family 2 member 6
chr3_-_194351290 1.41 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr22_-_37244237 1.41 ENST00000401529.3
ENST00000249071.11
RAC2
Rac family small GTPase 2
chr19_+_17527250 1.37 ENST00000599164.6
ENST00000449408.6
ENST00000600871.5
ENST00000599124.1
NIBAN3
niban apoptosis regulator 3
chr9_-_127755243 1.36 ENST00000629203.2
ENST00000420366.5
SH2D3C
SH2 domain containing 3C
chr12_-_92145838 1.29 ENST00000256015.5
BTG1
BTG anti-proliferation factor 1
chr1_+_207496229 1.21 ENST00000367051.6
ENST00000367053.6
ENST00000367052.6
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr3_+_52495330 1.19 ENST00000321725.10
STAB1
stabilin 1
chr7_+_22727147 1.18 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
IL6
interleukin 6
chr2_+_218880844 1.17 ENST00000258411.8
WNT10A
Wnt family member 10A
chr4_-_73998669 1.16 ENST00000296027.5
CXCL5
C-X-C motif chemokine ligand 5
chr1_+_37474572 1.11 ENST00000373087.7
ZC3H12A
zinc finger CCCH-type containing 12A
chr19_+_14031746 1.10 ENST00000263379.4
IL27RA
interleukin 27 receptor subunit alpha
chr19_-_17847962 1.09 ENST00000458235.7
ENST00000534444.1
JAK3
Janus kinase 3
chr15_-_40307825 1.08 ENST00000456256.6
ENST00000557821.5
PLCB2
phospholipase C beta 2
chrX_-_66033664 1.07 ENST00000427538.5
VSIG4
V-set and immunoglobulin domain containing 4
chr19_-_46625037 1.06 ENST00000596260.1
ENST00000594275.1
ENST00000597185.1
ENST00000598865.5
ENST00000291294.7
PTGIR
prostaglandin I2 receptor
chr10_+_12349533 1.04 ENST00000619168.5
CAMK1D
calcium/calmodulin dependent protein kinase ID
chr22_+_22343185 1.03 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr2_+_233693659 1.03 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase family 1 member A6
chr12_+_6946468 1.03 ENST00000543115.5
ENST00000399448.5
PTPN6
protein tyrosine phosphatase non-receptor type 6
chr19_+_17527232 1.02 ENST00000601861.5
NIBAN3
niban apoptosis regulator 3
chrX_-_153926757 1.02 ENST00000461052.5
ENST00000422091.1
ARHGAP4
Rho GTPase activating protein 4
chr13_-_77918820 1.00 ENST00000646607.2
EDNRB
endothelin receptor type B
chr22_-_37244417 1.00 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
RAC2
Rac family small GTPase 2
chr7_+_142715314 0.98 ENST00000390399.3
TRBV27
T cell receptor beta variable 27
chr1_-_7940825 0.97 ENST00000377507.8
TNFRSF9
TNF receptor superfamily member 9
chr19_-_6591103 0.96 ENST00000423145.7
ENST00000245903.4
CD70
CD70 molecule
chr15_-_40307910 0.95 ENST00000543785.3
ENST00000260402.8
PLCB2
phospholipase C beta 2
chr6_+_29723421 0.93 ENST00000259951.12
ENST00000434407.6
HLA-F
major histocompatibility complex, class I, F
chr13_-_77918788 0.93 ENST00000626030.1
EDNRB
endothelin receptor type B
chr18_-_72867945 0.92 ENST00000327305.11
NETO1
neuropilin and tolloid like 1
chr14_+_102777461 0.90 ENST00000560371.5
ENST00000347662.8
TRAF3
TNF receptor associated factor 3
chr14_-_106005574 0.90 ENST00000390595.3
IGHV1-3
immunoglobulin heavy variable 1-3
chr1_-_202159977 0.90 ENST00000367279.8
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr14_+_102777433 0.89 ENST00000392745.8
TRAF3
TNF receptor associated factor 3
chr12_-_48924919 0.87 ENST00000444214.6
FKBP11
FKBP prolyl isomerase 11
chr16_+_2019777 0.87 ENST00000566435.4
NPW
neuropeptide W
chr14_-_24576240 0.83 ENST00000216336.3
CTSG
cathepsin G
chr22_+_22427517 0.83 ENST00000390300.2
IGLV5-37
immunoglobulin lambda variable 5-37
chr1_-_204467216 0.83 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr11_+_75717811 0.82 ENST00000198801.10
MOGAT2
monoacylglycerol O-acyltransferase 2
chr6_+_29723340 0.81 ENST00000334668.8
HLA-F
major histocompatibility complex, class I, F
chr22_+_37282464 0.79 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
CYTH4
cytohesin 4
chr12_-_102917203 0.79 ENST00000553106.6
ENST00000307000.7
PAH
phenylalanine hydroxylase
chr12_+_103930332 0.77 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
HSP90B1
heat shock protein 90 beta family member 1
chr1_+_207496268 0.76 ENST00000529814.1
CR1
complement C3b/C4b receptor 1 (Knops blood group)
chr1_-_202161575 0.76 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr12_-_54588516 0.76 ENST00000547431.5
PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
chrX_+_68693629 0.76 ENST00000374597.3
STARD8
StAR related lipid transfer domain containing 8
chr15_-_44711306 0.74 ENST00000682850.1
PATL2
PAT1 homolog 2
chr4_+_165874833 0.73 ENST00000506144.1
TLL1
tolloid like 1
chr12_-_54984667 0.73 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
TESPA1
thymocyte expressed, positive selection associated 1
chr11_-_124935973 0.73 ENST00000298251.5
HEPACAM
hepatic and glial cell adhesion molecule
chr21_+_42403856 0.72 ENST00000291535.11
UBASH3A
ubiquitin associated and SH3 domain containing A
chr12_+_57230086 0.72 ENST00000414700.7
ENST00000557703.5
SHMT2
serine hydroxymethyltransferase 2
chr12_-_14961256 0.71 ENST00000541380.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr14_+_102777555 0.71 ENST00000539721.5
ENST00000560463.5
TRAF3
TNF receptor associated factor 3
chr19_+_45001430 0.71 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB
RELB proto-oncogene, NF-kB subunit
chr15_+_57599411 0.70 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr14_+_52267683 0.70 ENST00000306051.3
ENST00000553372.1
PTGDR
prostaglandin D2 receptor
chr2_-_100105339 0.69 ENST00000424600.5
ENST00000441400.5
ENST00000673328.1
AFF3
AF4/FMR2 family member 3
chr16_+_57358775 0.69 ENST00000219235.5
CCL22
C-C motif chemokine ligand 22
chr12_+_57229694 0.69 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
SHMT2
serine hydroxymethyltransferase 2
chr4_+_61200318 0.67 ENST00000683033.1
ADGRL3
adhesion G protein-coupled receptor L3
chr1_-_202160577 0.66 ENST00000629151.2
ENST00000476061.5
ENST00000464870.5
ENST00000467283.5
ENST00000435759.6
ENST00000486116.5
ENST00000477625.5
PTPN7
protein tyrosine phosphatase non-receptor type 7
chr12_-_54981838 0.66 ENST00000316577.12
TESPA1
thymocyte expressed, positive selection associated 1
chr7_-_22500152 0.66 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP1B
STEAP family member 1B
chr14_+_75522531 0.64 ENST00000555504.1
BATF
basic leucine zipper ATF-like transcription factor
chr4_+_73869385 0.62 ENST00000395761.4
CXCL1
C-X-C motif chemokine ligand 1
chr9_-_95317671 0.62 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FANCC
FA complementation group C
chr2_-_100104530 0.62 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AFF3
AF4/FMR2 family member 3
chrX_+_15500800 0.62 ENST00000348343.11
BMX
BMX non-receptor tyrosine kinase
chr2_+_158968608 0.61 ENST00000263635.8
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr6_+_116461364 0.61 ENST00000368606.7
ENST00000368605.3
CALHM6
calcium homeostasis modulator family member 6
chr14_+_75522427 0.60 ENST00000286639.8
BATF
basic leucine zipper ATF-like transcription factor
chr10_+_94762673 0.59 ENST00000480405.2
ENST00000371321.9
CYP2C19
cytochrome P450 family 2 subfamily C member 19
chr22_+_36922040 0.59 ENST00000406230.5
CSF2RB
colony stimulating factor 2 receptor subunit beta
chr17_-_40665121 0.59 ENST00000394052.5
KRT222
keratin 222
chr1_-_186680411 0.58 ENST00000367468.10
PTGS2
prostaglandin-endoperoxide synthase 2
chr11_+_278398 0.58 ENST00000534750.6
NLRP6
NLR family pyrin domain containing 6
chr2_+_113406368 0.57 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr1_-_160070150 0.57 ENST00000644903.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr5_-_151141631 0.57 ENST00000523714.5
ENST00000521749.5
ANXA6
annexin A6
chr5_-_180072086 0.55 ENST00000261947.4
RNF130
ring finger protein 130
chr2_+_233917371 0.55 ENST00000324695.9
ENST00000433712.6
TRPM8
transient receptor potential cation channel subfamily M member 8
chr12_+_100473875 0.55 ENST00000649582.1
NR1H4
nuclear receptor subfamily 1 group H member 4
chr14_+_103123452 0.54 ENST00000558056.1
ENST00000560869.6
TNFAIP2
TNF alpha induced protein 2
chr12_+_2053311 0.54 ENST00000399617.6
ENST00000683482.1
CACNA1C
calcium voltage-gated channel subunit alpha1 C
chr13_+_32031300 0.53 ENST00000642040.1
FRY
FRY microtubule binding protein
chr3_+_50205240 0.52 ENST00000610458.4
SLC38A3
solute carrier family 38 member 3
chr13_+_31945826 0.52 ENST00000647500.1
FRY
FRY microtubule binding protein
chr1_-_19288764 0.52 ENST00000361640.5
AKR7A3
aldo-keto reductase family 7 member A3
chr14_+_22086401 0.52 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr14_+_23969874 0.52 ENST00000534993.5
ENST00000543805.6
ENST00000558293.7
DHRS4L2
ENSG00000285467.1
dehydrogenase/reductase 4 like 2
novel transcript
chr6_+_32637419 0.52 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr21_-_41953997 0.51 ENST00000380486.4
C2CD2
C2 calcium dependent domain containing 2
chr7_+_90154442 0.51 ENST00000297205.7
STEAP1
STEAP family member 1
chr15_+_90184912 0.51 ENST00000561085.1
ENST00000332496.10
SEMA4B
semaphorin 4B
chr8_+_72537219 0.50 ENST00000523207.2
KCNB2
potassium voltage-gated channel subfamily B member 2
chr14_-_64503775 0.50 ENST00000608382.6
ZBTB25
zinc finger and BTB domain containing 25
chr16_+_2009870 0.50 ENST00000567649.1
NPW
neuropeptide W
chr12_+_2053545 0.50 ENST00000682336.1
ENST00000344100.7
ENST00000399591.5
ENST00000399595.5
ENST00000399597.5
ENST00000399601.5
ENST00000399606.5
ENST00000399621.5
ENST00000399629.5
ENST00000399637.5
ENST00000399638.5
ENST00000399644.5
ENST00000399649.5
ENST00000402845.7
ENST00000682686.1
CACNA1C
calcium voltage-gated channel subunit alpha1 C
chr11_+_102317542 0.50 ENST00000532808.5
BIRC3
baculoviral IAP repeat containing 3
chr12_-_8662703 0.50 ENST00000535336.5
MFAP5
microfibril associated protein 5
chr12_+_57230301 0.50 ENST00000553474.5
SHMT2
serine hydroxymethyltransferase 2
chr1_-_205775449 0.49 ENST00000235932.8
ENST00000437324.6
ENST00000414729.1
ENST00000367139.8
RAB29
RAB29, member RAS oncogene family
chr5_-_150412743 0.49 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74
CD74 molecule
chrX_-_132218124 0.49 ENST00000342983.6
RAP2C
RAP2C, member of RAS oncogene family
chr7_+_1232865 0.49 ENST00000316333.9
UNCX
UNC homeobox
chr20_-_59032292 0.48 ENST00000395663.1
ENST00000243997.8
ENST00000395659.1
ATP5F1E
ATP synthase F1 subunit epsilon
chr1_-_160070102 0.48 ENST00000638728.1
ENST00000637644.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr3_-_186544377 0.48 ENST00000307944.6
CRYGS
crystallin gamma S
chr9_+_4490388 0.48 ENST00000262352.8
SLC1A1
solute carrier family 1 member 1
chr14_+_51847145 0.48 ENST00000615906.4
GNG2
G protein subunit gamma 2
chr11_+_308188 0.48 ENST00000680619.1
ENST00000681833.1
ENST00000680261.1
IFITM2
interferon induced transmembrane protein 2
chr3_+_188153870 0.48 ENST00000416784.5
ENST00000430340.5
ENST00000414139.5
ENST00000454789.5
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_78944985 0.48 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
CTSH
cathepsin H
chr9_-_133703700 0.47 ENST00000371868.5
SARDH
sarcosine dehydrogenase
chr6_-_32668368 0.47 ENST00000399084.5
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr14_-_22829779 0.46 ENST00000488800.5
SLC7A7
solute carrier family 7 member 7
chr8_-_80171106 0.46 ENST00000519303.6
TPD52
tumor protein D52
chr22_-_50270353 0.45 ENST00000330651.11
MAPK11
mitogen-activated protein kinase 11
chr14_+_22829879 0.45 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr2_+_210556590 0.45 ENST00000233072.10
ENST00000619804.1
CPS1
carbamoyl-phosphate synthase 1
chr11_+_102317492 0.45 ENST00000673846.1
BIRC3
baculoviral IAP repeat containing 3
chr12_+_57230124 0.45 ENST00000553529.5
ENST00000554310.5
SHMT2
serine hydroxymethyltransferase 2
chr4_-_48681171 0.45 ENST00000505759.1
FRYL
FRY like transcription coactivator
chr14_-_24232332 0.45 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1
NEDD8
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr3_-_39153512 0.44 ENST00000273153.10
CSRNP1
cysteine and serine rich nuclear protein 1
chr7_+_86643902 0.44 ENST00000361669.7
GRM3
glutamate metabotropic receptor 3
chr18_-_55401026 0.44 ENST00000562607.5
TCF4
transcription factor 4
chr20_-_44651683 0.44 ENST00000537820.1
ENST00000372874.9
ADA
adenosine deaminase
chr12_+_100473708 0.44 ENST00000548884.5
ENST00000392986.8
NR1H4
nuclear receptor subfamily 1 group H member 4
chr5_+_119268689 0.43 ENST00000274456.6
TNFAIP8
TNF alpha induced protein 8
chr9_-_120926752 0.43 ENST00000373887.8
TRAF1
TNF receptor associated factor 1
chr21_+_33403466 0.43 ENST00000405436.5
IFNGR2
interferon gamma receptor 2
chr2_-_96857984 0.42 ENST00000393537.5
ANKRD39
ankyrin repeat domain 39
chr12_+_57230336 0.42 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
SHMT2
serine hydroxymethyltransferase 2
chr12_+_100473916 0.42 ENST00000549996.5
NR1H4
nuclear receptor subfamily 1 group H member 4
chr6_+_132570322 0.42 ENST00000275198.1
TAAR6
trace amine associated receptor 6
chr1_+_100538131 0.41 ENST00000315033.5
GPR88
G protein-coupled receptor 88
chr12_-_108598002 0.41 ENST00000549447.1
TMEM119
transmembrane protein 119
chr4_+_39044995 0.41 ENST00000261425.7
ENST00000508137.6
KLHL5
kelch like family member 5
chr8_+_53880867 0.41 ENST00000522225.5
RGS20
regulator of G protein signaling 20
chr11_+_102317450 0.40 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
BIRC3
baculoviral IAP repeat containing 3
chr12_-_48865863 0.40 ENST00000309739.6
RND1
Rho family GTPase 1
chr1_-_204411804 0.40 ENST00000367188.5
PPP1R15B
protein phosphatase 1 regulatory subunit 15B
chr12_-_54588636 0.40 ENST00000257905.13
PPP1R1A
protein phosphatase 1 regulatory inhibitor subunit 1A
chr8_-_65842051 0.39 ENST00000401827.8
PDE7A
phosphodiesterase 7A
chr3_-_138329839 0.39 ENST00000333911.9
ENST00000383180.6
NME9
NME/NM23 family member 9
chr17_+_4731410 0.39 ENST00000575284.5
ENST00000293777.6
ENST00000674339.1
ENST00000573708.1
MED11
mediator complex subunit 11
chr1_+_23791962 0.38 ENST00000421070.1
LYPLA2
lysophospholipase 2
chr10_+_87659839 0.38 ENST00000456849.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_-_67054100 0.37 ENST00000235345.6
SLC35D1
solute carrier family 35 member D1
chr22_-_19525369 0.37 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr1_+_24502894 0.37 ENST00000436717.6
ENST00000616511.4
RCAN3
RCAN family member 3
chr6_-_36387736 0.36 ENST00000373737.8
ENST00000373738.4
ENST00000538992.3
ENST00000615781.4
ENST00000620358.4
ETV7
ETS variant transcription factor 7
chr11_-_5154757 0.36 ENST00000380367.3
OR52A1
olfactory receptor family 52 subfamily A member 1
chr19_+_1261091 0.36 ENST00000588411.5
CIRBP
cold inducible RNA binding protein
chr1_+_11189347 0.36 ENST00000376819.4
ANGPTL7
angiopoietin like 7
chr8_+_53880894 0.36 ENST00000276500.4
RGS20
regulator of G protein signaling 20
chr1_+_112619824 0.35 ENST00000263168.4
CAPZA1
capping actin protein of muscle Z-line subunit alpha 1
chr19_+_15082211 0.35 ENST00000641398.1
OR1I1
olfactory receptor family 1 subfamily I member 1
chr15_+_34102037 0.35 ENST00000397766.4
PGBD4
piggyBac transposable element derived 4
chr13_+_32031706 0.35 ENST00000542859.6
FRY
FRY microtubule binding protein
chr13_+_108269629 0.35 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr1_-_24187246 0.35 ENST00000374421.7
ENST00000374418.3
ENST00000327575.6
ENST00000327535.6
IFNLR1
interferon lambda receptor 1
chr14_+_64504719 0.35 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_-_205775182 0.34 ENST00000446390.6
RAB29
RAB29, member RAS oncogene family
chr1_-_6261053 0.34 ENST00000377893.3
GPR153
G protein-coupled receptor 153
chr14_+_24232422 0.33 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
GMPR2
guanosine monophosphate reductase 2
chr17_-_42388360 0.33 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
STAT3
signal transducer and activator of transcription 3
chr6_+_29942523 0.33 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
HLA-A
major histocompatibility complex, class I, A
chr2_+_60881553 0.33 ENST00000394479.4
REL
REL proto-oncogene, NF-kB subunit
chrX_-_20266606 0.33 ENST00000643085.1
ENST00000645270.1
ENST00000644368.1
RPS6KA3
ribosomal protein S6 kinase A3
chr2_+_26346086 0.33 ENST00000613142.4
ENST00000260585.12
ENST00000447170.1
SELENOI
selenoprotein I
chr14_-_72894091 0.33 ENST00000556509.6
DPF3
double PHD fingers 3
chr1_-_89175997 0.33 ENST00000294671.3
ENST00000650452.1
GBP7
guanylate binding protein 7
chr15_+_85380625 0.32 ENST00000560302.5
AKAP13
A-kinase anchoring protein 13
chr14_+_64503708 0.32 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.7 2.0 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.5 1.5 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.4 1.9 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.4 1.1 GO:2000627 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 3.0 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.3 1.2 GO:1990637 response to prolactin(GO:1990637)
0.3 1.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 0.8 GO:0031247 actin rod assembly(GO:0031247)
0.3 9.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 1.3 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.3 2.5 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 1.4 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 1.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 0.7 GO:0061402 asparagine transport(GO:0006867) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402) regulation of glutamine transport(GO:2000485)
0.2 1.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.2 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 2.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.6 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.2 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.8 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.2 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 1.3 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.5 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 1.6 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.2 0.5 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 1.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.4 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.7 GO:0071461 cellular response to redox state(GO:0071461)
0.1 3.0 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.5 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 1.4 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.8 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 14.4 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 0.3 GO:0097187 dentinogenesis(GO:0097187)
0.1 1.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.0 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.6 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.3 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 1.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 1.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 2.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.7 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.6 GO:0050955 thermoception(GO:0050955)
0.1 1.2 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.1 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.1 1.3 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.0 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0030221 basophil differentiation(GO:0030221)
0.0 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.5 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 2.3 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.4 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.4 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.8 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0050915 detection of chemical stimulus involved in sensory perception of taste(GO:0050912) sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.8 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 1.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.8 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.3 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.3 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 3.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 3.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 2.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0019815 B cell receptor complex(GO:0019815)
0.2 3.0 GO:0070552 BRISC complex(GO:0070552)
0.2 0.6 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.2 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.8 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 3.2 GO:0042611 MHC protein complex(GO:0042611)
0.1 2.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 3.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.8 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 11.9 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 2.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.6 3.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.5 5.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 3.0 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.3 1.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.7 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.2 1.7 GO:0046979 TAP2 binding(GO:0046979)
0.2 1.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.2 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.8 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 2.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.5 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.2 2.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 1.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 1.5 GO:0016015 morphogen activity(GO:0016015)
0.1 0.5 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.8 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.3 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.8 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.2 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 1.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.8 GO:0001727 lipid kinase activity(GO:0001727)
0.1 16.1 GO:0003823 antigen binding(GO:0003823)
0.1 2.3 GO:0070628 proteasome binding(GO:0070628)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 2.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.5 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 1.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 1.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393) thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 1.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 2.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 4.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 3.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 9.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 2.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 2.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells