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Illumina Body Map 2 (GSE30611)

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Results for RFX3_RFX2

Z-value: 7.14

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.16 regulatory factor X3
ENSG00000087903.13 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg38_v1_chr19_-_6199510_61995640.655.5e-05Click!
RFX3hg38_v1_chr9_-_3489426_34894870.631.3e-04Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_42496186 37.16 ENST00000398352.3
ENST00000291536.8
radial spoke head component 1
chr1_-_109113818 28.46 ENST00000369949.8
chromosome 1 open reading frame 194
chr1_-_169427428 27.31 ENST00000456107.1
ENST00000367805.7
ENST00000491570.2
coiled-coil domain containing 181
chr1_-_159900112 23.55 ENST00000479940.2
ENST00000368099.9
cilia and flagella associated protein 45
chr1_-_169427408 22.31 ENST00000367806.7
coiled-coil domain containing 181
chr19_-_56840661 21.37 ENST00000649735.1
ENST00000593695.5
ENST00000599577.5
ENST00000594389.1
ENST00000648694.1
ENST00000326441.15
ENST00000649680.1
ENST00000649876.1
ENST00000650632.1
ENST00000650102.1
ENST00000647621.1
ENST00000598410.5
ENST00000649233.1
ENST00000593711.6
ENST00000629319.2
ENST00000599935.5
paternally expressed 3
zinc finger imprinted 2
chr12_+_48183602 21.35 ENST00000316554.5
coiled-coil domain containing 184
chr15_+_43510945 20.80 ENST00000382031.5
microtubule associated protein 1A
chrX_-_48835553 19.48 ENST00000218230.6
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_-_75668566 19.47 ENST00000526740.3
microtubule associated protein 6
chr1_+_42463221 18.99 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr5_-_150289764 18.93 ENST00000671881.1
ENST00000672752.1
ENST00000510347.2
ENST00000672829.1
ENST00000348628.11
calcium/calmodulin dependent protein kinase II alpha
chr5_-_150289625 18.76 ENST00000683332.1
ENST00000398376.8
ENST00000672785.1
ENST00000672396.1
calcium/calmodulin dependent protein kinase II alpha
chr17_-_7205116 18.35 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr15_+_70892443 18.14 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr10_+_61662921 17.59 ENST00000648843.3
ENST00000330194.2
ENST00000389639.3
ciliary associated calcium binding coiled-coil 1
chr8_-_48735248 17.00 ENST00000262103.8
ENST00000523092.5
ENST00000433756.1
EF-hand calcium binding domain 1
chr17_-_76141240 16.85 ENST00000322957.7
forkhead box J1
chr2_+_227871618 16.67 ENST00000309931.3
ENST00000440997.1
dynein assembly factor with WD repeats 1
chr3_-_50345665 16.38 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr11_+_111514772 15.98 ENST00000375618.9
ENST00000529167.5
ENST00000332814.6
HOATZ cilia and flagella associated protein
chr19_-_46471484 15.88 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr11_-_75668434 15.84 ENST00000434603.2
microtubule associated protein 6
chr19_-_46471407 15.61 ENST00000438932.2
PNMA family member 8A
chr9_+_122159886 15.28 ENST00000373764.8
ENST00000536616.5
MORN repeat containing 5
chr1_+_161098320 15.15 ENST00000368011.9
ENST00000392192.6
kelch domain containing 9
chr4_+_153152163 15.12 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
tripartite motif containing 2
novel protein
chr6_-_109440504 15.07 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr17_+_9576627 14.94 ENST00000396219.7
ENST00000352665.10
cilia and flagella associated protein 52
chr5_+_34839154 14.60 ENST00000505624.5
ENST00000638320.2
tetratricopeptide repeat domain 23 like
chr1_-_154206327 14.52 ENST00000368525.4
chromosome 1 open reading frame 189
chr6_+_112087576 14.52 ENST00000368656.7
ENST00000604268.1
family with sequence similarity 229 member B
chr13_+_36432487 14.47 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr5_-_115169894 14.33 ENST00000513154.6
ENST00000508894.1
tripartite motif containing 36
chr18_-_50266481 14.10 ENST00000398545.5
cilia and flagella associated protein 53
chr16_+_84145256 14.09 ENST00000378553.10
dynein axonemal assembly factor 1
chr2_+_119544420 13.95 ENST00000413369.8
cilia and flagella associated protein 221
chr1_+_37556913 13.88 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr11_-_8593940 13.88 ENST00000315204.5
ENST00000396672.5
ENST00000431279.6
ENST00000418597.5
serine/threonine kinase 33
chr17_-_6831716 13.59 ENST00000338694.7
tektin 1
chr3_-_167380270 13.58 ENST00000392764.5
ENST00000675490.1
ENST00000474464.5
ENST00000392766.6
ENST00000485651.5
zinc finger B-box domain containing
chr4_-_176195563 13.57 ENST00000280191.7
spermatogenesis associated 4
chr17_-_5500997 13.44 ENST00000568641.2
novel protein
chr16_+_57694788 13.31 ENST00000569375.5
ENST00000569167.1
ENST00000394337.8
ENST00000360716.8
ENST00000563126.5
ENST00000336825.12
dynein regulatory complex subunit 7
chr1_+_43172324 13.07 ENST00000528956.5
ENST00000610710.4
ENST00000372492.9
ENST00000529956.5
cilia and flagella associated protein 57
chr1_-_173669835 13.01 ENST00000333279.3
ankyrin repeat domain 45
chr2_-_130144994 12.88 ENST00000457413.1
ENST00000409128.5
ENST00000441670.1
ENST00000409234.3
ENST00000409943.8
ENST00000392984.7
ENST00000310463.10
coiled-coil domain containing 74B
chr21_-_39445719 12.82 ENST00000438404.5
ENST00000358268.6
ENST00000411566.5
ENST00000451131.1
ENST00000418018.5
ENST00000415863.5
ENST00000426783.5
ENST00000485895.6
ENST00000288350.8
ENST00000448288.6
ENST00000456017.5
ENST00000434281.5
lebercilin LCA5 like
chr11_-_119381629 12.57 ENST00000260187.7
ENST00000455332.6
ubiquitin specific peptidase 2
chr4_-_75630473 12.56 ENST00000307465.9
cyclin dependent kinase like 2
chr2_+_79512993 12.56 ENST00000496558.5
ENST00000451966.5
ENST00000402739.9
ENST00000629316.2
catenin alpha 2
chr10_+_125896549 12.56 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr8_-_100106034 12.54 ENST00000360863.11
ENST00000617334.1
regulator of G protein signaling 22
chr12_+_85036310 12.52 ENST00000393212.7
ENST00000393217.7
leucine rich repeats and IQ motif containing 1
chr3_-_27369355 12.50 ENST00000429845.6
ENST00000341435.9
ENST00000435750.1
NIMA related kinase 10
chr16_+_58249910 12.49 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr1_+_151721508 12.09 ENST00000479191.2
regulatory subunit of type II PKA R-subunit domain containing 1
chr3_+_158571171 12.00 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr20_-_3781440 11.97 ENST00000379756.3
sperm flagellar 1
chr1_+_20186076 11.90 ENST00000375099.4
UBX domain protein 10
chr11_-_8594181 11.79 ENST00000358872.7
ENST00000454443.2
serine/threonine kinase 33
chr8_-_132675533 11.77 ENST00000620350.5
ENST00000518642.5
ENST00000250173.5
leucine rich repeat containing 6
chr13_+_36431898 11.77 ENST00000440264.5
cyclin A1
chr5_-_11589019 11.76 ENST00000511377.5
catenin delta 2
chr11_-_8594140 11.72 ENST00000534493.5
ENST00000422559.6
serine/threonine kinase 33
chr19_-_7926106 11.53 ENST00000318978.6
cortexin 1
chr1_-_36450410 11.40 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr6_-_32151899 11.39 ENST00000211413.10
proline rich transmembrane protein 1
chr17_+_58755821 11.37 ENST00000308249.4
protein phosphatase, Mg2+/Mn2+ dependent 1E
chr3_+_119703001 11.37 ENST00000273390.9
ENST00000463700.1
ENST00000648112.1
cilia and flagella associated protein 91
novel protein
chr11_-_112073980 11.26 ENST00000532211.5
ENST00000528775.6
ENST00000280350.10
ENST00000431456.6
PIH1 domain containing 2
chr11_+_134069060 11.14 ENST00000534549.5
ENST00000441717.3
ENST00000299106.9
junctional adhesion molecule 3
chr1_-_66924791 11.01 ENST00000371023.7
ENST00000371022.3
ENST00000371026.8
dynein axonemal intermediate chain 4
chr15_+_82262781 10.99 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000682753.1
ENST00000566861.5
ENST00000565432.1
stabilizer of axonemal microtubules 2
chr5_-_132737518 10.98 ENST00000403231.6
ENST00000378735.5
ENST00000618515.4
ENST00000378746.8
kinesin family member 3A
chr12_+_106601137 10.96 ENST00000357881.8
regulatory factor X4
chr3_-_149971200 10.96 ENST00000498307.5
ENST00000489155.1
profilin 2
chr6_-_165309598 10.90 ENST00000230301.9
chromosome 6 open reading frame 118
chr2_-_175005357 10.87 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr10_+_101588274 10.86 ENST00000626968.2
ENST00000370151.9
ENST00000370147.5
deleted in primary ciliary dyskinesia homolog (mouse)
chr11_+_94512452 10.82 ENST00000542198.3
chromosome 11 open reading frame 97
chr20_+_20052506 10.74 ENST00000340348.10
ENST00000245957.10
ENST00000674269.1
ENST00000377306.5
ENST00000377303.6
ENST00000475466.5
cilia and flagella associated protein 61
chr15_-_70892412 10.73 ENST00000249861.9
THAP domain containing 10
chr19_-_50786139 10.72 ENST00000562076.2
novel protein
chr2_+_131527833 10.70 ENST00000295171.10
ENST00000467992.6
ENST00000409856.8
coiled-coil domain containing 74A
chr16_+_27066919 10.53 ENST00000505035.3
chromosome 16 open reading frame 82
chr10_+_133160194 10.52 ENST00000478074.6
ENST00000684248.1
ENST00000304613.8
kinase non-catalytic C-lobe domain containing 1
chr2_-_232928127 10.44 ENST00000373552.8
ENST00000409079.1
neuronal guanine nucleotide exchange factor
chr2_+_38875962 10.44 ENST00000340556.11
ENST00000410014.5
ENST00000644631.3
ENST00000409665.5
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr1_+_160081529 10.43 ENST00000368088.4
potassium inwardly rectifying channel subfamily J member 9
chr1_+_240123121 10.27 ENST00000681210.1
formin 2
chr6_-_43510686 10.05 ENST00000372441.1
leucine rich repeat containing 73
chr19_+_53882186 10.04 ENST00000682028.1
ENST00000683513.1
ENST00000263431.4
ENST00000419486.1
protein kinase C gamma
chr1_+_217631337 10.01 ENST00000366933.5
spermatogenesis associated 17
chr6_-_24646021 9.96 ENST00000430948.6
ENST00000535378.5
ENST00000537886.5
ENST00000378214.8
KIAA0319
chr3_-_47282518 9.96 ENST00000425853.5
ENST00000452770.6
kinesin family member 9
chr4_-_86360039 9.93 ENST00000515650.2
ENST00000641724.1
ENST00000641607.1
ENST00000641324.1
ENST00000641903.1
ENST00000395157.9
ENST00000641823.1
ENST00000641873.1
ENST00000641102.1
ENST00000641462.2
ENST00000641217.1
ENST00000642006.1
ENST00000641020.1
ENST00000641110.1
ENST00000639175.1
ENST00000641485.1
ENST00000641864.1
ENST00000641954.1
ENST00000641647.1
ENST00000641459.1
ENST00000641762.1
ENST00000641777.1
ENST00000641208.1
ENST00000642015.1
ENST00000641493.1
ENST00000642032.1
ENST00000641010.1
ENST00000641287.1
ENST00000641943.1
ENST00000642103.1
ENST00000641047.1
ENST00000641166.1
ENST00000641207.1
mitogen-activated protein kinase 10
chr1_-_39691450 9.82 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr3_-_149971109 9.75 ENST00000239940.11
profilin 2
chr5_-_11588842 9.72 ENST00000503622.5
catenin delta 2
chr1_+_33081145 9.70 ENST00000294517.11
ENST00000373443.7
antizyme inhibitor 2
chr12_+_121918581 9.56 ENST00000397454.2
ENST00000288912.9
cilia and flagella associated protein 251
chr12_-_63668461 9.54 ENST00000324472.9
ENST00000538147.1
dpy-19 like 2
chr1_-_118185157 9.47 ENST00000336338.10
sperm associated antigen 17
chrX_+_118823762 9.46 ENST00000310164.3
zinc finger CCHC-type containing 12
chr7_+_129502517 9.46 ENST00000462322.3
small lysine rich protein 1
chr7_-_45088888 9.44 ENST00000490531.3
NAC alpha domain containing
chr1_-_6180265 9.36 ENST00000262450.8
chromodomain helicase DNA binding protein 5
chr3_-_47282752 9.36 ENST00000456548.5
ENST00000432493.5
ENST00000684063.1
ENST00000444589.6
kinesin family member 9
chr16_+_67807082 9.36 ENST00000567852.5
ENST00000565148.5
ENST00000388833.7
ENST00000561654.5
ENST00000431934.2
translin associated factor X interacting protein 1
chr16_-_67393486 9.27 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr13_+_30932638 9.18 ENST00000380473.8
testis expressed 26
chr10_+_22345445 9.17 ENST00000376603.6
ENST00000456231.6
ENST00000376624.8
ENST00000313311.10
ENST00000435326.5
sperm associated antigen 6
chr1_+_240123148 9.12 ENST00000681824.1
formin 2
chr11_+_102047422 9.10 ENST00000434758.7
ENST00000526781.5
ENST00000534360.1
cilia and flagella associated protein 300
chr3_-_58577648 9.08 ENST00000394481.5
family with sequence similarity 107 member A
chr4_+_86594301 8.97 ENST00000427191.6
ENST00000411767.7
ENST00000436978.5
ENST00000502971.5
protein tyrosine phosphatase non-receptor type 13
chr16_+_89657740 8.97 ENST00000566204.2
ENST00000301031.8
ENST00000579310.6
spermatogenesis associated 33
chr3_-_119034779 8.95 ENST00000489689.5
immunoglobulin superfamily member 11
chr16_+_29812150 8.93 ENST00000647876.1
ENST00000567551.2
ENST00000567659.3
ENST00000637565.1
ENST00000358758.12
ENST00000636619.1
proline rich transmembrane protein 2
chr3_-_197949869 8.89 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr2_+_55519610 8.88 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr9_+_132410183 8.86 ENST00000393216.3
ENST00000343036.6
cilia and flagella associated protein 77
chr3_-_58577367 8.82 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr7_+_77122609 8.82 ENST00000285871.5
coiled-coil domain containing 146
chr3_-_169812866 8.81 ENST00000446859.7
ENST00000522830.5
ENST00000522526.6
leucine rich repeat containing 34
chr3_+_158571215 8.75 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr12_+_6904962 8.74 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr3_+_158571153 8.71 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr7_-_101321723 8.68 ENST00000498704.6
ENST00000517481.5
ENST00000437644.2
ENST00000315322.10
ENST00000621899.4
intraflagellar transport 22
chr2_+_43774033 8.64 ENST00000260605.12
ENST00000406852.7
ENST00000398823.6
ENST00000605786.5
dynein cytoplasmic 2 light intermediate chain 1
chr16_-_71230676 8.50 ENST00000321489.9
ENST00000539973.5
ENST00000288168.14
ENST00000545267.1
ENST00000541601.5
ENST00000393567.7
ENST00000538248.5
HYDIN axonemal central pair apparatus protein
chr3_-_119034810 8.47 ENST00000393775.7
immunoglobulin superfamily member 11
chr2_+_55519586 8.43 ENST00000339012.7
cilia and flagella associated protein 36
chr10_+_122271292 8.39 ENST00000260723.6
BTB domain containing 16
chr5_-_55233586 8.35 ENST00000282572.5
cyclin O
chr8_-_97277890 8.34 ENST00000322128.5
TSPY like 5
chr12_+_6904733 8.33 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr3_-_196318170 8.33 ENST00000325318.10
dynein light chain Tctex-type 2B
chr11_+_134331874 8.31 ENST00000339772.9
ENST00000535456.7
galactosidase beta 1 like 2
chr14_+_32329341 8.30 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr16_+_29812230 8.27 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr2_+_213284379 8.17 ENST00000272898.11
ENST00000432529.6
ENST00000413312.5
ENST00000331683.10
ENST00000447990.1
sperm associated antigen 16
chr19_-_46428869 8.15 ENST00000617053.3
PNMA family member 8C
chr10_-_25016105 8.14 ENST00000376363.5
ENST00000331161.9
enkurin, TRPC channel interacting protein
chr19_-_46495857 8.12 ENST00000599531.2
PNMA family member 8B
chr21_+_17513003 8.11 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr8_+_143716318 8.10 ENST00000338033.9
ENST00000395107.8
ENST00000395108.2
mitogen-activated protein kinase 15
chr8_-_132675567 8.08 ENST00000519595.5
leucine rich repeat containing 6
chr1_+_111346590 8.08 ENST00000369737.4
ENST00000369738.9
primary cilia formation
chr18_+_34710249 8.06 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr6_+_116616467 8.00 ENST00000229554.10
ENST00000368581.8
ENST00000368580.4
radial spoke head component 4A
chr9_-_35812238 7.97 ENST00000396638.7
ENST00000340291.6
sperm associated antigen 8
chr1_-_183653307 7.86 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr4_-_86594037 7.83 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
mitogen-activated protein kinase 10
chr1_-_39691393 7.82 ENST00000372844.8
hippocalcin like 4
chr8_+_93700524 7.80 ENST00000522324.5
ENST00000518322.6
ENST00000522803.5
ENST00000423990.6
ENST00000620645.1
CBY1 interacting BAR domain containing 1
chr4_-_86360071 7.80 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
mitogen-activated protein kinase 10
chr21_+_39445824 7.78 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr12_-_62935117 7.77 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr2_-_110204967 7.77 ENST00000355301.8
ENST00000676053.1
ENST00000675067.1
ENST00000676028.1
ENST00000417665.5
ENST00000418527.1
ENST00000445609.7
ENST00000316534.8
ENST00000393272.7
nephrocystin 1
chr2_+_231198546 7.71 ENST00000349938.8
ENST00000682334.1
ENST00000682002.1
ENST00000683275.1
ENST00000611582.5
ENST00000436339.6
ENST00000683271.1
ENST00000440107.6
ENST00000684432.1
ENST00000682100.1
ENST00000682367.1
ENST00000683112.1
ENST00000682030.1
ENST00000684718.1
ENST00000683553.1
ENST00000683966.1
ENST00000683575.1
armadillo repeat containing 9
chr6_+_52420332 7.63 ENST00000636107.1
ENST00000371068.11
ENST00000636702.1
ENST00000635996.1
ENST00000636379.1
EF-hand domain containing 1
chr17_+_11598456 7.63 ENST00000579828.5
ENST00000262442.9
ENST00000454412.6
dynein axonemal heavy chain 9
chr1_-_109042093 7.62 ENST00000369962.8
ENST00000357672.7
ENST00000531337.1
ENST00000529074.1
ENST00000369965.8
WD repeat domain 47
chr17_+_43025203 7.61 ENST00000587250.4
Rho family GTPase 2
chr16_-_75556214 7.61 ENST00000568377.5
ENST00000565067.5
ENST00000258173.11
transmembrane protein 231
chr12_-_54259531 7.58 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr14_-_73714361 7.58 ENST00000316836.5
PNMA family member 1
chr15_+_70892809 7.56 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr1_-_36450279 7.56 ENST00000445843.7
organic solute carrier partner 1
chr11_-_27363190 7.53 ENST00000328697.11
ENST00000317945.6
coiled-coil domain containing 34
chr8_-_100105955 7.51 ENST00000523437.5
regulator of G protein signaling 22
chr4_-_152779710 7.48 ENST00000304337.3
tigger transposable element derived 4
chr16_+_67806765 7.47 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr6_+_108848387 7.40 ENST00000368972.7
ENST00000392644.9
armadillo repeat containing 2
chr2_-_2331225 7.40 ENST00000648627.1
ENST00000649663.1
ENST00000650560.1
ENST00000428368.7
ENST00000648316.1
ENST00000648665.1
ENST00000649313.1
ENST00000399161.7
ENST00000647738.2
myelin transcription factor 1 like
chr12_-_25195074 7.35 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr4_-_155376797 7.32 ENST00000650955.1
ENST00000515654.5
microtubule associated protein 9
chr1_-_21651819 7.31 ENST00000495204.5
RAP1 GTPase activating protein
chr1_-_24413717 7.31 ENST00000003583.12
ENST00000337248.9
sperm tail PG-rich repeat containing 1
chr16_+_8712943 7.27 ENST00000561870.5
ENST00000396600.6
4-aminobutyrate aminotransferase
chr22_-_37953541 7.21 ENST00000422191.1
ENST00000249079.6
ENST00000403305.6
ENST00000418863.5
ENST00000619227.4
ENST00000403026.5
chromosome 22 open reading frame 23
chr4_+_40749909 7.18 ENST00000316607.5
ENST00000381782.7
NOP2/Sun RNA methyltransferase family member 7
chr14_-_73950393 7.17 ENST00000651776.1
FAM161 centrosomal protein B
chr17_-_7204502 7.14 ENST00000486626.8
ENST00000648263.1
discs large MAGUK scaffold protein 4
chr19_+_2096873 7.12 ENST00000395307.6
ENST00000395301.8
ENST00000620263.4
IZUMO family member 4
chr10_-_133336862 7.08 ENST00000368555.3
ENST00000252939.9
ENST00000368558.1
calcyon neuron specific vesicular protein
chr9_+_97307645 7.05 ENST00000529487.3
coiled-coil domain containing 180
chr17_-_15341577 7.02 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
tektin 3
chr20_+_63554142 6.96 ENST00000370097.2
fibronectin type III domain containing 11
chr16_+_19718264 6.96 ENST00000564186.5
IQ motif containing K
chr5_-_134367144 6.93 ENST00000265334.9
cyclin dependent kinase like 3
chr9_-_35812142 6.93 ENST00000497810.1
ENST00000484764.5
sperm associated antigen 8
chrX_+_86714623 6.93 ENST00000484479.1
dachshund family transcription factor 2
chr11_-_115504389 6.90 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr2_-_44361555 6.88 ENST00000409957.5
prolyl endopeptidase like
chr1_+_109114097 6.86 ENST00000457623.6
ENST00000369939.8
ENST00000529753.5
endosome-lysosome associated apoptosis and autophagy regulator 1
chr3_+_50269140 6.86 ENST00000616701.5
ENST00000433753.4
ENST00000611067.4
semaphorin 3B
chr2_+_158795309 6.83 ENST00000309950.8
ENST00000621326.4
ENST00000409042.5
death associated protein like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 18.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
4.1 32.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
3.9 19.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
3.5 146.7 GO:0044458 motile cilium assembly(GO:0044458)
3.2 9.7 GO:0015847 putrescine transport(GO:0015847)
3.0 9.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
3.0 8.9 GO:1902490 regulation of sperm capacitation(GO:1902490)
2.9 11.5 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
2.7 13.4 GO:0098904 regulation of AV node cell action potential(GO:0098904)
2.4 7.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
2.1 8.4 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
2.0 10.0 GO:0032425 positive regulation of mismatch repair(GO:0032425)
2.0 29.9 GO:0007258 JUN phosphorylation(GO:0007258)
1.8 27.4 GO:0007288 sperm axoneme assembly(GO:0007288)
1.8 7.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.8 7.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
1.8 3.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
1.7 15.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.6 22.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
1.6 14.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.6 11.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.6 9.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.6 29.6 GO:0003341 cilium movement(GO:0003341)
1.5 65.6 GO:0035082 axoneme assembly(GO:0035082)
1.5 7.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.5 31.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
1.5 14.6 GO:0097338 response to clozapine(GO:0097338)
1.4 20.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.4 15.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.3 5.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.3 24.9 GO:0060294 cilium movement involved in cell motility(GO:0060294)
1.2 3.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.2 3.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
1.2 14.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.1 9.1 GO:0018095 protein polyglutamylation(GO:0018095)
1.1 7.9 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
1.1 7.6 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
1.1 8.6 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
1.1 9.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.0 3.1 GO:0051041 positive regulation of calcium-independent cell-cell adhesion(GO:0051041)
1.0 10.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.0 6.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
1.0 20.1 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.0 11.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
1.0 4.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.0 5.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.9 16.5 GO:0045475 locomotor rhythm(GO:0045475)
0.9 6.0 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.8 5.7 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.8 13.0 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.8 0.8 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.8 4.8 GO:0033504 somite specification(GO:0001757) floor plate development(GO:0033504)
0.8 11.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.8 6.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.8 6.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.7 5.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7 8.2 GO:0036371 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.7 17.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.6 1.9 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.6 5.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.6 26.2 GO:0007141 male meiosis I(GO:0007141)
0.6 7.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 1.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.5 2.2 GO:0060166 olfactory pit development(GO:0060166)
0.5 4.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.5 1.6 GO:0034092 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.5 5.9 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.5 5.5 GO:0044782 cilium organization(GO:0044782)
0.5 1.5 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.5 27.2 GO:0007340 acrosome reaction(GO:0007340)
0.5 26.9 GO:0042073 intraciliary transport(GO:0042073)
0.5 19.5 GO:0002021 response to dietary excess(GO:0002021)
0.5 1.0 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.5 2.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.5 3.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.5 11.4 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.5 3.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.5 1.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 18.1 GO:0071801 regulation of podosome assembly(GO:0071801)
0.4 9.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.4 3.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.4 4.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.4 2.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.4 3.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 7.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.4 1.1 GO:0014028 notochord formation(GO:0014028)
0.4 1.1 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.4 7.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.4 19.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.4 1.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.3 1.0 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.3 7.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 3.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.3 4.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 2.0 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.3 1.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 4.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 32.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 3.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 17.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 3.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.3 1.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 5.8 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.3 3.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 1.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.3 0.8 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 1.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 2.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 4.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 13.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 0.8 GO:0042245 RNA repair(GO:0042245)
0.3 11.3 GO:0048665 neuron fate specification(GO:0048665)
0.2 0.7 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 6.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 31.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 1.0 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 4.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 5.6 GO:0043584 nose development(GO:0043584)
0.2 16.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 34.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 1.8 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.2 7.1 GO:0034389 lipid particle organization(GO:0034389)
0.2 0.4 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 4.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 4.2 GO:0007220 Notch receptor processing(GO:0007220)
0.2 6.0 GO:0097320 membrane tubulation(GO:0097320)
0.2 4.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 4.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 15.8 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.2 2.8 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2 13.6 GO:0010107 potassium ion import(GO:0010107)
0.2 0.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 1.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 33.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 4.7 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.2 1.0 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.2 12.4 GO:0014047 glutamate secretion(GO:0014047)
0.2 4.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 39.8 GO:0060271 cilium morphogenesis(GO:0060271)
0.2 2.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 23.0 GO:0007286 spermatid development(GO:0007286)
0.2 9.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 16.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 8.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 4.6 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 8.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 8.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 19.7 GO:0007338 single fertilization(GO:0007338)
0.1 6.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 6.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 9.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.1 3.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 3.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 10.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 1.9 GO:0021522 ventral spinal cord development(GO:0021517) spinal cord motor neuron differentiation(GO:0021522)
0.1 6.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 4.7 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 3.1 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.1 4.3 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.1 3.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 3.8 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 4.1 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 6.0 GO:0006739 NADP metabolic process(GO:0006739)
0.1 5.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 8.2 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.8 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.5 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.4 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 3.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 5.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 1.1 GO:0001302 replicative cell aging(GO:0001302)
0.1 0.2 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 3.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 3.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 1.3 GO:0008038 neuron recognition(GO:0008038)
0.1 3.5 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 3.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 3.6 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.1 2.6 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 2.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 6.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 3.7 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.1 3.3 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.1 0.4 GO:0038016 insulin receptor internalization(GO:0038016)
0.1 1.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.3 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 4.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 5.6 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.4 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 2.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 16.3 GO:0007411 axon guidance(GO:0007411)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 1.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 1.8 GO:0048255 mRNA stabilization(GO:0048255)
0.0 4.1 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 19.3 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 6.4 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 1.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 1.1 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 4.4 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 4.1 GO:0022900 electron transport chain(GO:0022900)
0.0 2.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.8 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 3.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 2.8 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.8 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.6 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 2.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.3 GO:0042308 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.0 0.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 8.0 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 1.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.6 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.7 GO:0030042 actin filament depolymerization(GO:0030042)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 26.1 GO:1990716 axonemal central apparatus(GO:1990716)
7.8 62.2 GO:0002177 manchette(GO:0002177)
6.6 26.2 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
6.2 18.7 GO:0001534 radial spoke(GO:0001534)
3.7 11.0 GO:0016939 kinesin II complex(GO:0016939)
3.4 37.2 GO:0072687 meiotic spindle(GO:0072687)
3.0 9.0 GO:0097224 sperm connecting piece(GO:0097224)
2.0 6.0 GO:0097545 axonemal outer doublet(GO:0097545)
1.9 9.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.4 48.5 GO:0030992 intraciliary transport particle B(GO:0030992)
1.4 14.1 GO:0005879 axonemal microtubule(GO:0005879)
1.3 25.5 GO:0098839 postsynaptic density membrane(GO:0098839)
1.2 7.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.1 131.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
1.0 6.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.0 5.7 GO:1990769 proximal neuron projection(GO:1990769)
0.9 9.3 GO:0097427 microtubule bundle(GO:0097427)
0.9 6.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.8 5.7 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.8 15.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.8 39.3 GO:0034451 centriolar satellite(GO:0034451)
0.8 5.3 GO:0097149 centralspindlin complex(GO:0097149)
0.7 13.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.7 4.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.7 20.3 GO:0035869 ciliary transition zone(GO:0035869)
0.7 16.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 3.8 GO:0043291 RAVE complex(GO:0043291)
0.6 112.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.6 11.1 GO:0033010 paranodal junction(GO:0033010)
0.6 6.8 GO:0032433 filopodium tip(GO:0032433)
0.5 6.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.5 14.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 8.5 GO:0001520 outer dense fiber(GO:0001520)
0.5 4.8 GO:0036128 CatSper complex(GO:0036128)
0.5 11.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 4.8 GO:0044294 dendritic growth cone(GO:0044294)
0.4 6.3 GO:0097542 ciliary tip(GO:0097542)
0.4 5.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 7.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 9.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 6.3 GO:0097546 ciliary base(GO:0097546)
0.4 2.6 GO:0034464 BBSome(GO:0034464)
0.4 29.7 GO:0036064 ciliary basal body(GO:0036064)
0.4 3.2 GO:0098536 deuterosome(GO:0098536)
0.3 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 3.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 31.2 GO:0005871 kinesin complex(GO:0005871)
0.3 4.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 2.6 GO:0070847 core mediator complex(GO:0070847)
0.3 123.2 GO:0005929 cilium(GO:0005929)
0.3 19.0 GO:0009925 basal plasma membrane(GO:0009925)
0.3 7.0 GO:0048786 presynaptic active zone(GO:0048786)
0.2 22.6 GO:0043195 terminal bouton(GO:0043195)
0.2 0.7 GO:0070939 Dsl1p complex(GO:0070939)
0.2 9.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 2.5 GO:0000242 pericentriolar material(GO:0000242)
0.2 36.6 GO:0042734 presynaptic membrane(GO:0042734)
0.2 126.2 GO:0005874 microtubule(GO:0005874)
0.2 16.2 GO:0005801 cis-Golgi network(GO:0005801)
0.2 6.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 4.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 1.5 GO:0032021 NELF complex(GO:0032021)
0.2 3.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 7.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.6 GO:0071920 cleavage body(GO:0071920)
0.2 1.1 GO:0043196 varicosity(GO:0043196)
0.2 19.4 GO:0005902 microvillus(GO:0005902)
0.2 6.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 12.0 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 22.0 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0032797 SMN complex(GO:0032797)
0.1 7.7 GO:0016235 aggresome(GO:0016235)
0.1 13.3 GO:0005776 autophagosome(GO:0005776)
0.1 12.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 17.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 7.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 5.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 3.0 GO:0031201 SNARE complex(GO:0031201)
0.1 3.5 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.6 GO:0031417 NatC complex(GO:0031417)
0.1 15.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 11.1 GO:0030496 midbody(GO:0030496)
0.1 3.5 GO:0035861 site of double-strand break(GO:0035861)
0.1 3.8 GO:0005814 centriole(GO:0005814)
0.1 67.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 24.4 GO:0043025 neuronal cell body(GO:0043025)
0.1 3.1 GO:0005581 collagen trimer(GO:0005581)
0.1 8.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 4.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 2.0 GO:0032420 stereocilium(GO:0032420)
0.0 6.5 GO:1902911 protein kinase complex(GO:1902911)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 15.7 GO:0045202 synapse(GO:0045202)
0.0 2.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 11.1 GO:0005813 centrosome(GO:0005813)
0.0 3.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 5.4 GO:0098793 presynapse(GO:0098793)
0.0 3.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 4.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.4 GO:0015030 Cajal body(GO:0015030)
0.0 13.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 19.4 GO:0043005 neuron projection(GO:0043005)
0.0 4.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0097451 astrocyte projection(GO:0097449) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 2.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 4.1 GO:0005119 smoothened binding(GO:0005119)
3.2 9.7 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
2.5 25.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.5 10.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
2.3 7.0 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
2.3 9.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.3 29.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.9 5.6 GO:0031862 prostanoid receptor binding(GO:0031862)
1.8 31.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.8 5.3 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.6 6.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.5 22.5 GO:0045504 dynein heavy chain binding(GO:0045504)
1.4 5.8 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.2 13.4 GO:0071253 connexin binding(GO:0071253)
1.2 3.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
1.1 8.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.1 5.3 GO:0004802 transketolase activity(GO:0004802)
1.1 10.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
1.0 3.1 GO:0031737 CX3C chemokine receptor binding(GO:0031737)
1.0 6.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.0 3.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.9 6.6 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.9 2.8 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.9 3.7 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.9 20.1 GO:0070840 dynein complex binding(GO:0070840)
0.8 8.4 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.8 5.7 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.8 21.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.8 7.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.7 5.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.7 2.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.7 9.0 GO:0032027 myosin light chain binding(GO:0032027)
0.7 6.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 4.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.6 15.4 GO:0045503 dynein light chain binding(GO:0045503)
0.6 8.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.6 15.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 16.5 GO:0030332 cyclin binding(GO:0030332)
0.6 4.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.6 19.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.6 2.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.5 13.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 7.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 42.1 GO:0003777 microtubule motor activity(GO:0003777)
0.5 17.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.5 6.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 25.4 GO:0003785 actin monomer binding(GO:0003785)
0.4 5.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 2.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.4 7.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.4 1.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.4 1.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.4 1.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.4 9.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.4 1.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 27.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 5.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 10.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 8.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 146.8 GO:0008017 microtubule binding(GO:0008017)
0.3 11.1 GO:0044548 S100 protein binding(GO:0044548)
0.3 6.8 GO:0070513 death domain binding(GO:0070513)
0.3 7.4 GO:0004707 MAP kinase activity(GO:0004707)
0.3 11.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 2.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.3 1.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 4.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 2.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.3 3.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 6.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 1.0 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 5.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 14.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 3.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 5.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 15.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 4.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 6.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.8 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 14.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 33.3 GO:0030165 PDZ domain binding(GO:0030165)
0.2 2.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 0.8 GO:0035514 DNA demethylase activity(GO:0035514)
0.2 13.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 4.1 GO:0031432 titin binding(GO:0031432)
0.2 7.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 9.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.2 11.8 GO:0030507 spectrin binding(GO:0030507)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 2.9 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 19.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 4.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 4.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 44.3 GO:0005516 calmodulin binding(GO:0005516)
0.1 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 26.1 GO:0008013 beta-catenin binding(GO:0008013)
0.1 22.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 3.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 5.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 8.1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 6.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 10.0 GO:0015631 tubulin binding(GO:0015631)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 5.6 GO:0030552 cAMP binding(GO:0030552)
0.1 4.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 5.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 9.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 5.3 GO:0051018 protein kinase A binding(GO:0051018)
0.1 3.1 GO:0005521 lamin binding(GO:0005521)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 6.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 13.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 29.6 GO:0003924 GTPase activity(GO:0003924)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 5.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 9.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 6.6 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.1 4.9 GO:0045182 translation regulator activity(GO:0045182)
0.1 18.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 9.9 GO:0005496 steroid binding(GO:0005496)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 9.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 6.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 3.3 GO:0043022 ribosome binding(GO:0043022)
0.0 3.5 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 4.9 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459)
0.0 5.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 16.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 9.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 11.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 3.4 GO:0005178 integrin binding(GO:0005178)
0.0 16.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 4.6 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 8.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.0 GO:0002020 protease binding(GO:0002020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 21.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.7 35.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7 36.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.6 25.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 29.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 25.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 11.1 PID ATM PATHWAY ATM pathway
0.2 12.9 PID AURORA B PATHWAY Aurora B signaling
0.2 9.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 9.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 8.8 PID IL3 PATHWAY IL3-mediated signaling events
0.1 10.0 PID FGF PATHWAY FGF signaling pathway
0.1 6.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 7.2 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 5.0 PID PLK1 PATHWAY PLK1 signaling events
0.1 4.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 9.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target  Total log-likelihood Term