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Illumina Body Map 2 (GSE30611)

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Results for RORC

Z-value: 0.52

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Transcription factors associated with RORC

Gene Symbol Gene ID Gene Info
ENSG00000143365.19 RAR related orphan receptor C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORChg38_v1_chr1_-_151831768_1518318330.106.0e-01Click!

Activity profile of RORC motif

Sorted Z-values of RORC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_7060676 7.59 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
complement C1s
chr12_+_7061206 2.66 ENST00000423384.5
ENST00000413211.5
complement C1s
chr11_-_64759967 2.23 ENST00000377432.7
ENST00000164139.4
glycogen phosphorylase, muscle associated
chrX_-_103276741 2.04 ENST00000372680.2
transcription elongation factor A like 5
chr20_-_23452857 1.68 ENST00000377007.3
ENST00000377009.8
cystatin 11
chr19_-_42423100 1.19 ENST00000597001.1
lipase E, hormone sensitive type
chr11_+_31816266 1.14 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr20_+_38581186 1.14 ENST00000373348.4
ENST00000537425.2
ENST00000416116.2
adipogenin
chrX_+_70282093 1.13 ENST00000509895.5
ENST00000374473.6
ENST00000276066.4
RAB41, member RAS oncogene family
chr1_-_235649734 1.04 ENST00000391854.7
G protein subunit gamma 4
chr19_-_7633713 0.96 ENST00000311069.6
Purkinje cell protein 2
chr19_-_7632971 0.94 ENST00000598935.5
Purkinje cell protein 2
chr7_-_141841473 0.93 ENST00000350549.8
ENST00000438520.1
serine protease 37
chr6_-_46954922 0.92 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr11_-_47594399 0.82 ENST00000302514.4
C1q and TNF related 4
chr3_-_42410558 0.77 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr3_-_50322759 0.72 ENST00000442581.1
ENST00000447092.5
hyaluronidase 2
chr4_+_168712159 0.71 ENST00000510998.5
palladin, cytoskeletal associated protein
chr17_-_10804092 0.71 ENST00000581851.1
transmembrane protein 238 like
chr6_-_119078642 0.69 ENST00000621231.4
ENST00000338891.12
family with sequence similarity 184 member A
chr20_+_46894581 0.69 ENST00000357410.7
ENST00000611592.4
EYA transcriptional coactivator and phosphatase 2
chr3_-_50322733 0.66 ENST00000428028.1
ENST00000357750.9
hyaluronidase 2
chr7_-_712940 0.62 ENST00000544935.5
ENST00000430040.5
ENST00000456696.2
ENST00000406797.5
protein kinase cAMP-dependent type I regulatory subunit beta
chr8_-_94436926 0.53 ENST00000481490.3
fibrinogen silencer binding protein
chr8_+_39913881 0.51 ENST00000518237.6
indoleamine 2,3-dioxygenase 1
chr10_-_104085847 0.50 ENST00000648076.2
collagen type XVII alpha 1 chain
chr3_-_65597886 0.50 ENST00000460329.6
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_-_101818425 0.49 ENST00000361464.8
ENST00000439817.5
O-GlcNAcase
chr14_+_21317547 0.47 ENST00000557351.1
RPGR interacting protein 1
chr12_+_93570381 0.44 ENST00000549206.5
suppressor of cytokine signaling 2
chr12_+_93569814 0.42 ENST00000340600.6
suppressor of cytokine signaling 2
chr10_-_101818405 0.40 ENST00000357797.9
ENST00000370094.7
O-GlcNAcase
chr8_+_66043413 0.39 ENST00000522619.1
DnaJ heat shock protein family (Hsp40) member C5 beta
chr6_-_136526654 0.38 ENST00000611373.1
microtubule associated protein 7
chr8_-_126557691 0.35 ENST00000652209.1
LRAT domain containing 2
chr14_+_21317535 0.35 ENST00000382933.8
RPGR interacting protein 1
chr20_-_41317602 0.34 ENST00000559234.5
ENST00000683867.1
zinc fingers and homeoboxes 3
chr20_+_31637905 0.34 ENST00000376075.4
cytochrome c oxidase subunit 4I2
chr6_-_111605859 0.34 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3 interacting protein 2
chr1_-_157099798 0.31 ENST00000454449.3
ETS variant transcription factor 3 like
chr3_-_45915698 0.28 ENST00000539217.5
leucine zipper transcription factor like 1
chr3_+_185586270 0.28 ENST00000296257.10
SUMO specific peptidase 2
chr1_+_103655760 0.27 ENST00000370083.9
amylase alpha 1A
chr19_-_39245006 0.26 ENST00000413851.3
ENST00000613087.4
interferon lambda 3
chr4_-_86849366 0.25 ENST00000273905.7
solute carrier family 10 member 6
chr17_-_61863327 0.25 ENST00000584322.2
ENST00000682369.1
ENST00000683039.1
ENST00000683381.1
BRCA1 interacting protein C-terminal helicase 1
chr16_+_1782940 0.24 ENST00000262302.14
ENST00000563136.5
ENST00000565987.5
ENST00000568287.5
ENST00000565134.5
nucleotide binding protein 2
chr14_-_23286038 0.24 ENST00000673724.1
homeobox and leucine zipper encoding
chr11_+_67605488 0.23 ENST00000533876.1
ENST00000647561.1
novel transcript
NADH:ubiquinone oxidoreductase core subunit V1
chr19_-_46077093 0.23 ENST00000601672.5
IGF like family member 4
chr5_+_178130996 0.23 ENST00000515098.5
ENST00000502814.5
ENST00000313386.9
ENST00000507457.5
ENST00000508647.5
required for meiotic nuclear division 5 homolog B
chr6_+_43770707 0.22 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr19_+_39268394 0.21 ENST00000331982.6
interferon lambda 2
chr6_+_43770202 0.21 ENST00000372067.8
ENST00000672860.2
vascular endothelial growth factor A
chr13_+_108596152 0.20 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr2_-_148020689 0.16 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
origin recognition complex subunit 4
chr3_-_165196689 0.16 ENST00000241274.3
SLIT and NTRK like family member 3
chr1_+_159826799 0.16 ENST00000368104.4
SLAM family member 8
chr3_-_184378136 0.16 ENST00000445696.6
thrombopoietin
chr1_+_154567770 0.16 ENST00000368476.4
cholinergic receptor nicotinic beta 2 subunit
chr19_+_1269266 0.16 ENST00000585630.5
ENST00000589710.5
ENST00000628979.2
ENST00000586773.5
ENST00000587323.5
ENST00000589686.5
ENST00000588230.5
ENST00000413636.6
ENST00000587896.6
ENST00000320936.9
ENST00000589235.5
ENST00000591659.5
cold inducible RNA binding protein
chr2_-_29921580 0.16 ENST00000389048.8
ALK receptor tyrosine kinase
chr2_-_148020754 0.15 ENST00000440042.1
ENST00000536575.5
origin recognition complex subunit 4
chr12_+_56021005 0.14 ENST00000547167.6
IKAROS family zinc finger 4
chr14_-_23286082 0.14 ENST00000357460.7
homeobox and leucine zipper encoding
chr1_-_61725121 0.13 ENST00000371177.2
ENST00000606498.5
TM2 domain containing 1
chr3_-_165196369 0.13 ENST00000475390.2
SLIT and NTRK like family member 3
chr14_-_53951880 0.12 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chr22_-_32464440 0.11 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr2_+_148021083 0.11 ENST00000642680.2
methyl-CpG binding domain protein 5
chr7_-_128775793 0.10 ENST00000249389.3
opsin 1, short wave sensitive
chr1_+_159826860 0.10 ENST00000289707.10
SLAM family member 8
chr12_+_4562192 0.08 ENST00000543431.5
dual specificity tyrosine phosphorylation regulated kinase 4
chr3_+_187743654 0.08 ENST00000648485.1
BCL6 antisense 1
chr10_+_100535927 0.07 ENST00000299163.7
hypoxia inducible factor 1 subunit alpha inhibitor
chr10_-_104085793 0.04 ENST00000650263.1
collagen type XVII alpha 1 chain
chr16_-_69351778 0.03 ENST00000288025.4
transmembrane p24 trafficking protein 6
chr7_-_30550761 0.01 ENST00000598361.4
ENST00000440438.6
novel protein
GARS1 divergent transcript
chr12_+_12908961 0.01 ENST00000540125.1
G protein-coupled receptor class C group 5 member A

Network of associatons between targets according to the STRING database.

First level regulatory network of RORC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 1.4 GO:0019087 transformation of host cell by virus(GO:0019087)
0.2 1.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.7 GO:0036269 swimming behavior(GO:0036269)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.9 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.2 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 2.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.7 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 10.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.5 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 1.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.3 1.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 11.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.9 GO:0051393 alpha-actinin binding(GO:0051393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters